#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y5X4 uniprotkb:Q9UNY5 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-749023|ensembl:ENSP00000250076 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:zn232_human(display_long)|uniprotkb:Zinc finger and SCAN domain-containing protein 11(gene name synonym)|uniprotkb:ZNF232(gene name)|psi-mi:ZNF232(display_short)|uniprotkb:ZSCAN11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665807|imex:IM-28774-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) refseq:NP_055334.2|refseq:NP_001307882.1|refseq:NP_001307883.1|ensembl:ENSG00000167840(gene)|ensembl:ENST00000250076(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016880510.1|entrezgene/locuslink:7775(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:18jIzxhG0JCfrQpWx8F7FkmYnQ09606 rigid:fxAaeNzUIQNec6ebNFwrw5lC8Bs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:Q16533 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-11915024|ensembl:ENSP00000216294 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:snpc1_human(display_long)|uniprotkb:SNAPC1(gene name)|psi-mi:SNAPC1(display_short)|uniprotkb:Proximal sequence element-binding transcription factor subunit gamma(gene name synonym)|uniprotkb:SNAP43(gene name synonym)|uniprotkb:Small nuclear RNA-activating complex polypeptide 1(gene name synonym)|uniprotkb:snRNA-activating protein complex 43 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665799|imex:IM-28774-1403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) ensembl:ENSG00000023608(gene)|ensembl:ENST00000216294(transcript)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR019188|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|refseq:NP_003073.1|dip:DIP-504N|entrezgene/locuslink:6617(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:xXCySYpmgoo2VmzFtT1iRFFUkj49606 rigid:8Xd7EJZGu9fCN+h+hjeQls6DVXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:P37231 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665783|imex:IM-28774-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:05B0BKDbXqVTR2ANMwqQXsqiCzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:P31276 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-2293590|uniprotkb:Q5BL02|uniprotkb:Q96J32|uniprotkb:Q9NR24|uniprotkb:Q9NYD5|ensembl:ENSP00000243056 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:hxc13_human(display_long)|uniprotkb:HOXC13(gene name)|psi-mi:HOXC13(display_short)|uniprotkb:HOX3G(gene name synonym)|uniprotkb:Homeobox protein Hox-3G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665775|imex:IM-28774-2721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) refseq:NP_059106.2|ensembl:ENSG00000123364(gene)|ensembl:ENST00000243056(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:3229(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:sGnVE8V9ZSPBuUnE8vdLLosrIa49606 rigid:ckZCMqTaJ9V68zrfxd2QNsISKwI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQL6 uniprotkb:Q06413 intact:EBI-715576|uniprotkb:O60340|uniprotkb:O60528|uniprotkb:Q96DY4|intact:EBI-28970762|uniprotkb:C9JFV9|ensembl:ENSP00000468004|ensembl:ENSP00000507606 intact:EBI-2684075|uniprotkb:D7F7N5|uniprotkb:F8W7V7|uniprotkb:C9JMZ0|ensembl:ENSP00000396219|ensembl:ENSP00000421925|ensembl:ENSP00000490473 psi-mi:hdac5_human(display_long)|uniprotkb:Antigen NY-CO-9(gene name synonym)|uniprotkb:HDAC5(gene name)|psi-mi:HDAC5(display_short)|uniprotkb:KIAA0600(gene name synonym) psi-mi:mef2c_human(display_long)|uniprotkb:MEF2C(gene name)|psi-mi:MEF2C(display_short)|uniprotkb:Myocyte enhancer factor 2C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665823|imex:IM-28774-941 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015053.1|refseq:NP_005465.2|refseq:XP_005256963.1|ensembl:ENST00000225983|ensembl:ENSP00000225983|ensembl:ENST00000336057|ensembl:ENSP00000337290|ensembl:ENSP00000468004|ensembl:ENSP00000507606|dip:DIP-38260N|rcsb pdb:5UWI|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8943724|mint:Q9UQL6|ensembl:ENSG00000108840(gene)|ensembl:ENST00000586802(transcript)|ensembl:ENST00000682912(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR030703|interpro:IPR037138|entrezgene/locuslink:10014(identity) refseq:XP_011541702.1|refseq:XP_011541698.1|refseq:NP_001294931.1|refseq:NP_001124477.1|refseq:NP_001180276.1|refseq:NP_001180277.1|refseq:NP_001180278.1|refseq:NP_001180279.1|refseq:NP_002388.2|refseq:XP_005248568.1|refseq:XP_006714682.1|refseq:XP_006714688.1|refseq:XP_016864967.1|refseq:XP_016864968.1|refseq:XP_016864969.1|refseq:XP_016864970.1|dip:DIP-40857N|refseq:XP_016864965.1|refseq:XP_016864966.1|ensembl:ENSG00000081189(gene)|ensembl:ENST00000437473(transcript)|ensembl:ENST00000504921(transcript)|ensembl:ENST00000636294(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003185"(sinoatrial valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048666"(neuron development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007611"(learning or memory)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q06413|reactome:R-HSA-198753|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9022707|reactome:R-HSA-9707616|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|entrezgene/locuslink:4208(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fI8A5VuOawGthBb/65R47AEGZ/Y9606 rogid:vZxaYdzMYwHDAZZItu8N7SWZPic9606 rigid:8DbrOGyMhJEm0hKB4x5snK3xdcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:P05423 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665791|imex:IM-28774-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:zV218PJj7BQkjkJ8HwXi1BfFOYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQL6 uniprotkb:O43248 intact:EBI-715576|uniprotkb:O60340|uniprotkb:O60528|uniprotkb:Q96DY4|intact:EBI-28970762|uniprotkb:C9JFV9|ensembl:ENSP00000468004|ensembl:ENSP00000507606 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:hdac5_human(display_long)|uniprotkb:Antigen NY-CO-9(gene name synonym)|uniprotkb:HDAC5(gene name)|psi-mi:HDAC5(display_short)|uniprotkb:KIAA0600(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665815|imex:IM-28774-1405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015053.1|refseq:NP_005465.2|refseq:XP_005256963.1|ensembl:ENST00000225983|ensembl:ENSP00000225983|ensembl:ENST00000336057|ensembl:ENSP00000337290|ensembl:ENSP00000468004|ensembl:ENSP00000507606|dip:DIP-38260N|rcsb pdb:5UWI|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8943724|mint:Q9UQL6|ensembl:ENSG00000108840(gene)|ensembl:ENST00000586802(transcript)|ensembl:ENST00000682912(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR030703|interpro:IPR037138|entrezgene/locuslink:10014(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fI8A5VuOawGthBb/65R47AEGZ/Y9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:Vp6c4T5++BByy5q0Er2BWCZa700 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q9Y5X4 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665767|imex:IM-28774-1401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) - - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rigid:k1M6HwfEyZFcyFa1qzJo2MIOoDI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:Q12926 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-11285353|uniprotkb:D3DRK3|uniprotkb:Q13235|uniprotkb:Q59G15|uniprotkb:Q8NEM4|uniprotkb:Q9H1Q8|ensembl:ENSP00000369460|ensembl:ENSP00000380479|ensembl:ENSP00000440998 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:elav2_human(display_long)|uniprotkb:ELAVL2(gene name)|psi-mi:ELAVL2(display_short)|uniprotkb:ELAV-like neuronal protein 1(gene name synonym)|uniprotkb:HUB(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)|uniprotkb:Nervous system-specific RNA-binding protein Hel-N1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665759|imex:IM-28774-3141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) refseq:NP_001164666.1|refseq:NP_001164668.1|refseq:NP_004423.2|ensembl:ENSG00000107105(gene)|ensembl:ENST00000380117(transcript)|ensembl:ENST00000397312(transcript)|ensembl:ENST00000544538(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034914|interpro:IPR034999|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016869908.1|refseq:XP_016869909.1|refseq:XP_016869910.1|refseq:XP_016869911.1|refseq:XP_016869912.1|refseq:XP_016869913.1|refseq:XP_016869914.1|entrezgene/locuslink:1993(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:Z17PDyoxDFJbfrFlvD3xS91rtLk9606 rigid:B75WTVWF9fnZNImnKv3mDWxOG6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03701 uniprotkb:P61457 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665958|imex:IM-28774-1409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701|entrezgene/locuslink:10153(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:7Cl58R+Ksm39b+RWga6ExVpbZr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03701 uniprotkb:P48443 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665966|imex:IM-28774-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701|entrezgene/locuslink:10153(identity) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rigid:n8aKVmsYoXxZlRyk3aIfc+zmLWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03701 uniprotkb:P42226 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665974|imex:IM-28774-949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701|entrezgene/locuslink:10153(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:rDo127PxBO53URdVof9mSK8VyQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03701 uniprotkb:Q8N653 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665982|imex:IM-28774-951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701|entrezgene/locuslink:10153(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:NwC1q5tj8wrTJQoU/bPKsosWURw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQL6 uniprotkb:Q06413 intact:EBI-715576|uniprotkb:O60340|uniprotkb:O60528|uniprotkb:Q96DY4|intact:EBI-28970762|uniprotkb:C9JFV9|ensembl:ENSP00000468004|ensembl:ENSP00000507606 intact:EBI-2684075|uniprotkb:D7F7N5|uniprotkb:F8W7V7|uniprotkb:C9JMZ0|ensembl:ENSP00000396219|ensembl:ENSP00000421925|ensembl:ENSP00000490473 psi-mi:hdac5_human(display_long)|uniprotkb:Antigen NY-CO-9(gene name synonym)|uniprotkb:HDAC5(gene name)|psi-mi:HDAC5(display_short)|uniprotkb:KIAA0600(gene name synonym) psi-mi:mef2c_human(display_long)|uniprotkb:MEF2C(gene name)|psi-mi:MEF2C(display_short)|uniprotkb:Myocyte enhancer factor 2C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665831|imex:IM-28774-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015053.1|refseq:NP_005465.2|refseq:XP_005256963.1|ensembl:ENST00000225983|ensembl:ENSP00000225983|ensembl:ENST00000336057|ensembl:ENSP00000337290|ensembl:ENSP00000468004|ensembl:ENSP00000507606|dip:DIP-38260N|rcsb pdb:5UWI|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8943724|mint:Q9UQL6|ensembl:ENSG00000108840(gene)|ensembl:ENST00000586802(transcript)|ensembl:ENST00000682912(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR030703|interpro:IPR037138|entrezgene/locuslink:10014(identity) refseq:XP_011541702.1|refseq:XP_011541698.1|refseq:NP_001294931.1|refseq:NP_001124477.1|refseq:NP_001180276.1|refseq:NP_001180277.1|refseq:NP_001180278.1|refseq:NP_001180279.1|refseq:NP_002388.2|refseq:XP_005248568.1|refseq:XP_006714682.1|refseq:XP_006714688.1|refseq:XP_016864967.1|refseq:XP_016864968.1|refseq:XP_016864969.1|refseq:XP_016864970.1|dip:DIP-40857N|refseq:XP_016864965.1|refseq:XP_016864966.1|ensembl:ENSG00000081189(gene)|ensembl:ENST00000437473(transcript)|ensembl:ENST00000504921(transcript)|ensembl:ENST00000636294(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003185"(sinoatrial valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048666"(neuron development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007611"(learning or memory)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q06413|reactome:R-HSA-198753|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9022707|reactome:R-HSA-9707616|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|entrezgene/locuslink:4208(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fI8A5VuOawGthBb/65R47AEGZ/Y9606 rogid:vZxaYdzMYwHDAZZItu8N7SWZPic9606 rigid:8DbrOGyMhJEm0hKB4x5snK3xdcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQL6 uniprotkb:Q14814 intact:EBI-715576|uniprotkb:O60340|uniprotkb:O60528|uniprotkb:Q96DY4|intact:EBI-28970762|uniprotkb:C9JFV9|ensembl:ENSP00000468004|ensembl:ENSP00000507606 intact:EBI-2829828|uniprotkb:Q5T9U5|uniprotkb:Q14815|uniprotkb:Q5T9U6|uniprotkb:D3DVC0|ensembl:ENSP00000271555 psi-mi:hdac5_human(display_long)|uniprotkb:Antigen NY-CO-9(gene name synonym)|uniprotkb:HDAC5(gene name)|psi-mi:HDAC5(display_short)|uniprotkb:KIAA0600(gene name synonym) psi-mi:mef2d_human(display_long)|uniprotkb:MEF2D(gene name)|psi-mi:MEF2D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665839|imex:IM-28774-943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015053.1|refseq:NP_005465.2|refseq:XP_005256963.1|ensembl:ENST00000225983|ensembl:ENSP00000225983|ensembl:ENST00000336057|ensembl:ENSP00000337290|ensembl:ENSP00000468004|ensembl:ENSP00000507606|dip:DIP-38260N|rcsb pdb:5UWI|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8943724|mint:Q9UQL6|ensembl:ENSG00000108840(gene)|ensembl:ENST00000586802(transcript)|ensembl:ENST00000682912(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR030703|interpro:IPR037138|entrezgene/locuslink:10014(identity) refseq:XP_011507871.1|refseq:NP_005911.1|refseq:XP_016856803.1|refseq:XP_016856804.1|refseq:NP_001258558.1|refseq:XP_005245226.1|refseq:XP_005245227.1|refseq:XP_006711393.1|refseq:XP_006711395.1|refseq:XP_006711396.1|refseq:XP_006711397.1|ensembl:ENSG00000116604(gene)|ensembl:ENST00000348159(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9031628|reactome:R-HSA-9707616|go:"GO:0003700"(DNA-binding transcription factor activity)|entrezgene/locuslink:4209(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fI8A5VuOawGthBb/65R47AEGZ/Y9606 rogid:jedvDf/fMyonSO9j1epfMUuj86Y9606 rigid:OMuHh2tmn934Xml1UGjXiu+cXCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IX01 uniprotkb:Q8N653 intact:EBI-949116|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286|uniprotkb:O15071|uniprotkb:O60369|uniprotkb:Q5JPH7|uniprotkb:Q8WUF7|uniprotkb:C9JI71 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:sugp2_human(display_long)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665950|imex:IM-28774-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IX01|rcsb pdb:1X4P|refseq:NP_001017392.2|refseq:NP_055699.2|refseq:XP_016881626.1|refseq:NP_001308626.1|entrezgene/locuslink:10147(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:jR+BeUOvPjL36iBJVAFj+NN3LgY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14978 uniprotkb:P61457 intact:EBI-744493|uniprotkb:O43387|uniprotkb:Q96H95|uniprotkb:B2R634|ensembl:ENSP00000219069 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zn263_human(display_long)|uniprotkb:Zinc finger protein FPM315(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 12(gene name synonym)|uniprotkb:ZNF263(gene name)|psi-mi:ZNF263(display_short)|uniprotkb:FPM315(gene name synonym)|uniprotkb:ZKSCAN12(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665942|imex:IM-28774-2723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005732.2|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030752|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|ensembl:ENSG00000006194(gene)|ensembl:ENST00000219069(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:10127(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6W8A+hmUjdSzgIWT6wSAcwPaMLU9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:Dlg1EulRkRfrUUnC/jGCdewQSB4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VE28 uniprotkb:Q6PD29 intact:EBI-1538490|uniprotkb:Q3TYU5|uniprotkb:Q3UM34|uniprotkb:Q8C4J8|uniprotkb:Q91Y45|uniprotkb:Q9D7U9|ensembl:ENSMUSP00000022051 intact:EBI-3044009|ensembl:ENSMUSP00000110238|uniprotkb:Q3U4K1|uniprotkb:Q8BWH6 psi-mi:nkd2_mouse(display_long)|uniprotkb:Nkd2(gene name)|psi-mi:Nkd2(display_short) psi-mi:zn513_mouse(display_long)|uniprotkb:Znf513(gene name)|psi-mi:Znf513(display_short)|uniprotkb:Zfp513(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665934|imex:IM-28774-2305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082462.3|refseq:NP_001334464.1|ensembl:ENSMUSG00000021567(gene)|ensembl:ENSMUST00000022051(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140|entrezgene/locuslink:72293(identity) ensembl:ENSMUSG00000043059(gene)|ensembl:ENSMUST00000114590(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001171372.1|refseq:NP_780520.3|refseq:XP_006503720.2|entrezgene/locuslink:101023(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YahIfIwWuxWNCTmkeFs9nSf8UWc10090 rogid:Uv2jsMClXB89tOJP1vn8uzWMQUw10090 rigid:GX/JPOBrhH8Q2stmmAVpSShZiE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PD29 uniprotkb:Q07230 intact:EBI-3044009|ensembl:ENSMUSP00000110238|uniprotkb:Q3U4K1|uniprotkb:Q8BWH6 intact:EBI-26665895|ensembl:ENSMUSP00000042321 psi-mi:zn513_mouse(display_long)|uniprotkb:Znf513(gene name)|psi-mi:Znf513(display_short)|uniprotkb:Zfp513(gene name synonym) psi-mi:zsca2_mouse(display_long)|uniprotkb:Zinc finger protein 29(gene name synonym)|uniprotkb:Zscan2(gene name)|psi-mi:Zscan2(display_short)|uniprotkb:Zfp-29(gene name synonym)|uniprotkb:Zfp29(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665926|imex:IM-28774-2303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043059(gene)|ensembl:ENSMUST00000114590(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001171372.1|refseq:NP_780520.3|refseq:XP_006503720.2|entrezgene/locuslink:101023(identity) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|rcsb pdb:2I13|ensembl:ENSMUSG00000038797(gene)|ensembl:ENSMUST00000044115(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|refseq:NP_033579.1|refseq:XP_006540868.1|refseq:XP_006540869.1|refseq:XP_006540870.1|refseq:XP_006540871.1|refseq:XP_006540872.1|refseq:XP_006540873.1|refseq:XP_006540874.1|refseq:XP_006540875.1|entrezgene/locuslink:22691(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Uv2jsMClXB89tOJP1vn8uzWMQUw10090 rogid:TKkA1qeOjBvBBvqNNMoIA8zG87w10090 rigid:b19zmY9iR2nljjVhk8PYSAw/YGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13133 uniprotkb:Q8N653 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665887|imex:IM-28774-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|entrezgene/locuslink:10062(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:QM4ZKc7WC6ZPgF7mtNlEiyZz1gU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13111 uniprotkb:Q8N653 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665879|imex:IM-28774-1407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|entrezgene/locuslink:10036(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:w+rpZNgbdXW1Pa0DPMuOUp4m6ys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13111 uniprotkb:Q8N653 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665871|imex:IM-28774-2301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|entrezgene/locuslink:10036(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:w+rpZNgbdXW1Pa0DPMuOUp4m6ys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2X0 uniprotkb:Q8N653 intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665863|imex:IM-28774-947 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N|entrezgene/locuslink:10025(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:804kikoLxGDRgMpf5224KWdqU8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQL6 uniprotkb:Q14814 intact:EBI-715576|uniprotkb:O60340|uniprotkb:O60528|uniprotkb:Q96DY4|intact:EBI-28970762|uniprotkb:C9JFV9|ensembl:ENSP00000468004|ensembl:ENSP00000507606 intact:EBI-2829828|uniprotkb:Q5T9U5|uniprotkb:Q14815|uniprotkb:Q5T9U6|uniprotkb:D3DVC0|ensembl:ENSP00000271555 psi-mi:hdac5_human(display_long)|uniprotkb:Antigen NY-CO-9(gene name synonym)|uniprotkb:HDAC5(gene name)|psi-mi:HDAC5(display_short)|uniprotkb:KIAA0600(gene name synonym) psi-mi:mef2d_human(display_long)|uniprotkb:MEF2D(gene name)|psi-mi:MEF2D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665847|imex:IM-28774-945 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001015053.1|refseq:NP_005465.2|refseq:XP_005256963.1|ensembl:ENST00000225983|ensembl:ENSP00000225983|ensembl:ENST00000336057|ensembl:ENSP00000337290|ensembl:ENSP00000468004|ensembl:ENSP00000507606|dip:DIP-38260N|rcsb pdb:5UWI|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8943724|mint:Q9UQL6|ensembl:ENSG00000108840(gene)|ensembl:ENST00000586802(transcript)|ensembl:ENST00000682912(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR030703|interpro:IPR037138|entrezgene/locuslink:10014(identity) refseq:XP_011507871.1|refseq:NP_005911.1|refseq:XP_016856803.1|refseq:XP_016856804.1|refseq:NP_001258558.1|refseq:XP_005245226.1|refseq:XP_005245227.1|refseq:XP_006711393.1|refseq:XP_006711395.1|refseq:XP_006711396.1|refseq:XP_006711397.1|ensembl:ENSG00000116604(gene)|ensembl:ENST00000348159(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9031628|reactome:R-HSA-9707616|go:"GO:0003700"(DNA-binding transcription factor activity)|entrezgene/locuslink:4209(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fI8A5VuOawGthBb/65R47AEGZ/Y9606 rogid:jedvDf/fMyonSO9j1epfMUuj86Y9606 rigid:OMuHh2tmn934Xml1UGjXiu+cXCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2X0 uniprotkb:Q15744 intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665855|imex:IM-28774-1861 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N|entrezgene/locuslink:10025(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:BF7ra4aYSZSnA9eBQ2KqXMO90cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99909 uniprotkb:P24278 intact:EBI-10295431|uniprotkb:O60223|uniprotkb:Q9BRW7|uniprotkb:Q5JQZ3|ensembl:ENSP00000298396 intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746 psi-mi:ssx3_human(display_long)|uniprotkb:SSX3(gene name)|psi-mi:SSX3(display_short)|uniprotkb:Cancer/testis antigen 5.3(gene name synonym) psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665998|imex:IM-28774-3145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066294.1|refseq:XP_011542187.1|ensembl:ENSG00000165584(gene)|ensembl:ENST00000298396(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:10214(identity) refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jSB31TCCfnAP7jshF00a7bTb/sA9606 rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606 rigid:MSh2/Oupl4eSBSTt/OwGXsuyU+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z401 uniprotkb:Q15744 intact:EBI-1046479|ensembl:ENSP00000396830|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|uniprotkb:E7EPL3 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666006|imex:IM-28774-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000431932(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|ensembl:ENSG00000174485(gene)|mint:Q7Z401|reactome:R-HSA-8876198|refseq:NP_001138295.1|refseq:NP_005839.3|refseq:XP_005254178.1|refseq:XP_016877352.1|entrezgene/locuslink:10260(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:iEt4SEOGxR+S7GvC2iWA7JC+DvU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z401 uniprotkb:P61457 intact:EBI-1046479|ensembl:ENSP00000396830|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|uniprotkb:E7EPL3 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666014|imex:IM-28774-1863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000431932(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|ensembl:ENSG00000174485(gene)|mint:Q7Z401|reactome:R-HSA-8876198|refseq:NP_001138295.1|refseq:NP_005839.3|refseq:XP_005254178.1|refseq:XP_016877352.1|entrezgene/locuslink:10260(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:jQasOeMmagcFXFyHunLR04mB8dc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99LL5 uniprotkb:Q61545 intact:EBI-4285021|uniprotkb:Q9D6T6|ensembl:ENSMUSP00000001836 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:pwp1_mouse(display_long)|uniprotkb:Pwp1(gene name)|psi-mi:Pwp1(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666022|imex:IM-28774-1881 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598754.2|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q99LL5|ensembl:ENSMUSG00000001785(gene)|ensembl:ENSMUST00000001836(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|entrezgene/locuslink:103136(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+p9Zt4WaArKLsgVszp/FIYBjhUU10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:d02bk1Bu1Uhj1InJrurPUEVfnRg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q99LL5 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-4285021|uniprotkb:Q9D6T6|ensembl:ENSMUSP00000001836 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:pwp1_mouse(display_long)|uniprotkb:Pwp1(gene name)|psi-mi:Pwp1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666030|imex:IM-28774-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_598754.2|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q99LL5|ensembl:ENSMUSG00000001785(gene)|ensembl:ENSMUST00000001836(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|entrezgene/locuslink:103136(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:+p9Zt4WaArKLsgVszp/FIYBjhUU10090 rigid:s2p4TL0jNWMrv3NAut9YoWbKB4w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYM9 uniprotkb:Q15545 intact:EBI-954123|ensembl:ENSP00000369299|uniprotkb:Q15521|uniprotkb:Q05CQ0 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 psi-mi:tri22_human(display_long)|uniprotkb:RING finger protein 94(gene name synonym)|uniprotkb:50 kDa-stimulated trans-acting factor(gene name synonym)|uniprotkb:Staf-50(gene name synonym)|uniprotkb:Tripartite motif-containing protein 22(gene name synonym)|uniprotkb:TRIM22(gene name)|psi-mi:TRIM22(display_short)|uniprotkb:RNF94(gene name synonym)|uniprotkb:STAF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM22(gene name synonym) psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666046|imex:IM-28774-3147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132274(gene)|ensembl:ENST00000379965(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035827|interpro:IPR043136|mint:Q8IYM9|reactome:R-HSA-877300|go:"GO:0051607"(defense response to virus)|refseq:NP_001186502.1|refseq:NP_006065.2|entrezgene/locuslink:10346(identity) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:6879(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8CNTleevg3ll6+eu/3p28ysv1M09606 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rigid:IyjcGg8/bc+u+zmvrD3953BD4wE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NP66 uniprotkb:Q9NP66 intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78 intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78 psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym) psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666054|imex:IM-28774-1411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity) refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606 rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606 rigid:XZRYFGiJOQq1OwR6EMYLgxv1tX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:Q9Y5X4 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666070|imex:IM-28774-953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) - - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rigid:6MjGD81xTwGMCp7qvSzKPy683PA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:O43763 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666078|imex:IM-28774-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:Nb6chjJJozrK4dnhYh+gIrJIPfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:P31274 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666086|imex:IM-28774-955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:Y3g8jCNSYYp6EmSrupmwc00KX/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYM9 uniprotkb:P16220 intact:EBI-954123|ensembl:ENSP00000369299|uniprotkb:Q15521|uniprotkb:Q05CQ0 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:tri22_human(display_long)|uniprotkb:RING finger protein 94(gene name synonym)|uniprotkb:50 kDa-stimulated trans-acting factor(gene name synonym)|uniprotkb:Staf-50(gene name synonym)|uniprotkb:Tripartite motif-containing protein 22(gene name synonym)|uniprotkb:TRIM22(gene name)|psi-mi:TRIM22(display_short)|uniprotkb:RNF94(gene name synonym)|uniprotkb:STAF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM22(gene name synonym) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666038|imex:IM-28774-2321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132274(gene)|ensembl:ENST00000379965(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035827|interpro:IPR043136|mint:Q8IYM9|reactome:R-HSA-877300|go:"GO:0051607"(defense response to virus)|refseq:NP_001186502.1|refseq:NP_006065.2|entrezgene/locuslink:10346(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8CNTleevg3ll6+eu/3p28ysv1M09606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:Afo/SWPAMwTd7tffmcbbfG1yYFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:P10914 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-1055781|uniprotkb:Q96GG7|ensembl:ENSP00000245414|ensembl:ENSP00000384406 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:irf1_human(display_long)|uniprotkb:IRF1(gene name)|psi-mi:IRF1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666094|imex:IM-28774-2725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) refseq:NP_002189.1|ensembl:ENSG00000125347(gene)|ensembl:ENST00000245414(transcript)|ensembl:ENST00000405885(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043374"(CD8-positive, alpha-beta T cell differentiation)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR017431(Interferon regulatory factor, 1/2)|interpro:IPR019817|interpro:IPR031215|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5620971|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983231|dip:DIP-40988N|entrezgene/locuslink:3659(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:ToPrN31Dt6/EQuaX8gkxFBDJp5Q9606 rigid:4s/Qh050kDyNNylrB07YUtzIgig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:P14859 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666102|imex:IM-28774-961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rigid:1A/HvJt5XTHNVswsh1svmfmHjvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6T264 uniprotkb:O88522 intact:EBI-7650924|ensembl:ENSMUSP00000059210|uniprotkb:Q8BIU5|uniprotkb:Q505D8|uniprotkb:Q6PDK3|uniprotkb:Q5SUC2|uniprotkb:Q6ZQG5|uniprotkb:Q8R3T0|intact:MINT-8375705 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:maml1_mouse(display_long)|uniprotkb:Maml1(gene name)|psi-mi:Maml1(display_short)|uniprotkb:Kiaa0200(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666110|imex:IM-28774-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050567(gene)|ensembl:ENSMUST00000059458(transcript)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0060928"(atrioventricular node cell development)|interpro:IPR019082|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0010831"(positive regulation of myotube differentiation)|refseq:NP_780543.2|entrezgene/locuslink:103806(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Us4w80GoyIJvEFn21oB6J1MqGHg10090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:bpi3kbw1zBWZVoPDpGm8wW7Cicg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99909 uniprotkb:P35638 intact:EBI-10295431|uniprotkb:O60223|uniprotkb:Q9BRW7|uniprotkb:Q5JQZ3|ensembl:ENSP00000298396 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:ssx3_human(display_long)|uniprotkb:SSX3(gene name)|psi-mi:SSX3(display_short)|uniprotkb:Cancer/testis antigen 5.3(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26665990|imex:IM-28774-3143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066294.1|refseq:XP_011542187.1|ensembl:ENSG00000165584(gene)|ensembl:ENST00000298396(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:10214(identity) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) - - crc64:31905293FB1FBBE2 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jSB31TCCfnAP7jshF00a7bTb/sA9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:o2rK9h1RjIsDWdxx7K4O98uHD0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6T264 uniprotkb:Q924Z4 intact:EBI-7650924|ensembl:ENSMUSP00000059210|uniprotkb:Q8BIU5|uniprotkb:Q505D8|uniprotkb:Q6PDK3|uniprotkb:Q5SUC2|uniprotkb:Q6ZQG5|uniprotkb:Q8R3T0|intact:MINT-8375705 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 psi-mi:maml1_mouse(display_long)|uniprotkb:Maml1(gene name)|psi-mi:Maml1(display_short)|uniprotkb:Kiaa0200(gene name synonym) psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666126|imex:IM-28774-963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050567(gene)|ensembl:ENSMUST00000059458(transcript)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0060928"(atrioventricular node cell development)|interpro:IPR019082|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0010831"(positive regulation of myotube differentiation)|refseq:NP_780543.2|entrezgene/locuslink:103806(identity) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) - comment:mint comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Us4w80GoyIJvEFn21oB6J1MqGHg10090 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rigid:OfivmxkPe7/yhKIJ34GI6SANB7M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q96PK6 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666134|imex:IM-28774-965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|entrezgene/locuslink:10432(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 rigid:Kw5dhUF/zpM+hhR2RwPcncPtAR8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:P70662 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666168|imex:IM-28774-2309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:sQuKkrzGlK9AxC/WzbDUmuRYrVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:P70662 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666176|imex:IM-28774-3149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:sQuKkrzGlK9AxC/WzbDUmuRYrVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6T264 uniprotkb:Q9WTU0 intact:EBI-7650924|ensembl:ENSMUSP00000059210|uniprotkb:Q8BIU5|uniprotkb:Q505D8|uniprotkb:Q6PDK3|uniprotkb:Q5SUC2|uniprotkb:Q6ZQG5|uniprotkb:Q8R3T0|intact:MINT-8375705 intact:EBI-8339791|intact:MINT-4107441|uniprotkb:Q6A023|uniprotkb:Q80WA8|ensembl:ENSMUSP00000047308 psi-mi:maml1_mouse(display_long)|uniprotkb:Maml1(gene name)|psi-mi:Maml1(display_short)|uniprotkb:Kiaa0200(gene name synonym) psi-mi:phf2_mouse(display_long)|uniprotkb:Phf2(gene name)|psi-mi:Phf2(display_short)|uniprotkb:GRC5(gene name synonym)|uniprotkb:Kiaa0662(gene name synonym)|uniprotkb:PHD finger protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666118|imex:IM-28774-1883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050567(gene)|ensembl:ENSMUST00000059458(transcript)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0060928"(atrioventricular node cell development)|interpro:IPR019082|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0010831"(positive regulation of myotube differentiation)|refseq:NP_780543.2|entrezgene/locuslink:103806(identity) refseq:NP_035208.2|ensembl:ENSMUSG00000038025(gene)|ensembl:ENSMUST00000035540(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035574"(histone H4-K20 demethylation)|go:"GO:0035575"(histone H4-methyl-lysine-20 demethylase activity)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|mint:Q9WTU0|reactome:R-MMU-3214842|entrezgene/locuslink:18676(identity) - comment:mint comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Us4w80GoyIJvEFn21oB6J1MqGHg10090 rogid:2RoS6FXstspu+TN1DwCkVySJlUI10090 rigid:CVNL+9zy6BqoAdOMQ3BYPYL6xs4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:O55203 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666192|imex:IM-28774-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:Ik2+OZDj4djLBtVFgrxZRmA4MZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53776 uniprotkb:Q9CXV0 intact:EBI-26666200|ensembl:ENSMUSP00000027740|uniprotkb:O08916|uniprotkb:Q810K7|uniprotkb:Q9R280 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 psi-mi:lhx4_mouse(display_long)|uniprotkb:Lhx4(gene name)|psi-mi:Lhx4(display_short)|uniprotkb:Gsh-4(gene name synonym)|uniprotkb:Gsh4(gene name synonym) psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666236|imex:IM-28774-2727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026468(gene)|ensembl:ENSMUST00000027740(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|refseq:NP_034842.2|entrezgene/locuslink:16872(identity) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MK0SaLTxxzZ6TgZlXnEk1+pDECU10090 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rigid:bK3p/Ox2c0i5VWpELXLgCdL6onA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:Q9CYZ8 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666244|imex:IM-28774-967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:suUccmb3Kka0t7ZyflTBoPftMOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:O55203 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666184|imex:IM-28774-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:Ik2+OZDj4djLBtVFgrxZRmA4MZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92826 uniprotkb:Q15306 intact:EBI-11317274|uniprotkb:Q96QM4|uniprotkb:Q99810|uniprotkb:B2R878|ensembl:ENSP00000290295 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 psi-mi:hxb13_human(display_long)|uniprotkb:HOXB13(gene name)|psi-mi:HOXB13(display_short) psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666325|imex:IM-28774-2313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006352.2|ensembl:ENSG00000159184(gene)|ensembl:ENST00000290295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2CRA|rcsb pdb:5EDN|rcsb pdb:5EEA|rcsb pdb:5EF6|rcsb pdb:5EG0|rcsb pdb:5EGO|rcsb pdb:5NO6|entrezgene/locuslink:10481(identity) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1SnzRAM4GtQSqYfsGf209weqvyw9606 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rigid:8nl6YDWhqP58ce2xZRd694otNCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92826 uniprotkb:P09016 intact:EBI-11317274|uniprotkb:Q96QM4|uniprotkb:Q99810|uniprotkb:B2R878|ensembl:ENSP00000290295 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:hxb13_human(display_long)|uniprotkb:HOXB13(gene name)|psi-mi:HOXB13(display_short) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666317|imex:IM-28774-3161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006352.2|ensembl:ENSG00000159184(gene)|ensembl:ENST00000290295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2CRA|rcsb pdb:5EDN|rcsb pdb:5EEA|rcsb pdb:5EF6|rcsb pdb:5EG0|rcsb pdb:5EGO|rcsb pdb:5NO6|entrezgene/locuslink:10481(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1SnzRAM4GtQSqYfsGf209weqvyw9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:VgBKGCWe6cERHbmpKXgNqcpFVzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92826 uniprotkb:P19419 intact:EBI-11317274|uniprotkb:Q96QM4|uniprotkb:Q99810|uniprotkb:B2R878|ensembl:ENSP00000290295 intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4 psi-mi:hxb13_human(display_long)|uniprotkb:HOXB13(gene name)|psi-mi:HOXB13(display_short) psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666309|imex:IM-28774-1421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006352.2|ensembl:ENSG00000159184(gene)|ensembl:ENST00000290295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2CRA|rcsb pdb:5EDN|rcsb pdb:5EEA|rcsb pdb:5EF6|rcsb pdb:5EG0|rcsb pdb:5EGO|rcsb pdb:5NO6|entrezgene/locuslink:10481(identity) ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N|entrezgene/locuslink:2002(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1SnzRAM4GtQSqYfsGf209weqvyw9606 rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606 rigid:4yXQEpjP78WPbpxysHnbgZwZdSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00479 uniprotkb:Q01844 intact:EBI-2867693|uniprotkb:Q53XL9|uniprotkb:B2R4I6|ensembl:ENSP00000366798 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:hmgn4_human(display_long)|uniprotkb:HMGN4(gene name)|psi-mi:HMGN4(display_short)|uniprotkb:HMG17L3(gene name synonym)|uniprotkb:NHC(gene name synonym)|uniprotkb:Non-histone chromosomal protein HMG-17-like 3(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666301|imex:IM-28774-1413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006344.1|refseq:XP_016865660.1|refseq:XP_016865661.1|refseq:XP_016865662.1|ensembl:ENSG00000182952(gene)|ensembl:ENST00000377575(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:O00479|entrezgene/locuslink:10473(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S+sGfUyPi8TfoLIBhSfTTAK9bfA9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:rB/nmiDW2AI9fjU9KGdEGAg2N5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9CXV0 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666272|imex:IM-28774-3151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rigid:54eYRKsqZddzY8H9WD2bcAoE0qU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQG0 uniprotkb:P17482 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666341|imex:IM-28774-1423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|entrezgene/locuslink:10514(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:Ik/ZvxCvE4R/yyULxm4irNbAfA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:Q9CYZ8 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666256|imex:IM-28774-2311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:suUccmb3Kka0t7ZyflTBoPftMOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92826 uniprotkb:P14859 intact:EBI-11317274|uniprotkb:Q96QM4|uniprotkb:Q99810|uniprotkb:B2R878|ensembl:ENSP00000290295 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 psi-mi:hxb13_human(display_long)|uniprotkb:HOXB13(gene name)|psi-mi:HOXB13(display_short) psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666333|imex:IM-28774-1885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006352.2|ensembl:ENSG00000159184(gene)|ensembl:ENST00000290295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2CRA|rcsb pdb:5EDN|rcsb pdb:5EEA|rcsb pdb:5EF6|rcsb pdb:5EG0|rcsb pdb:5EGO|rcsb pdb:5NO6|entrezgene/locuslink:10481(identity) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1SnzRAM4GtQSqYfsGf209weqvyw9606 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rigid:TOur4mJR1iEHtyA0nqgjKO2Tp5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0P5 uniprotkb:Q9CXV0 intact:EBI-8607760|ensembl:ENSMUSP00000044368|intact:MINT-8177753 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 psi-mi:pygo1_mouse(display_long)|uniprotkb:Pygo1(gene name)|psi-mi:Pygo1(display_short) psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666264|imex:IM-28774-969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034910(gene)|ensembl:ENSMUST00000038489(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|rcsb pdb:2DX8|rcsb pdb:2YYR|reactome:R-MMU-201722|interpro:IPR019786|refseq:NP_082392.1|entrezgene/locuslink:72135(identity) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcuyU94M5VkU3ooZ8t9278flbd410090 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rigid:bhmW/yhaG5zFUAjzrTdp0HyUVIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXV0 uniprotkb:Q3U4B1 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666293|imex:IM-28774-3153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:HALSfypa3ljFLESZerlTImDGzE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R3P9 uniprotkb:Q3U4B1 intact:EBI-26666349|ensembl:ENSMUSP00000118312|uniprotkb:Q497V2|uniprotkb:Q5XK30|uniprotkb:Q8BHY5|uniprotkb:Q8BQM6|uniprotkb:Q921Y9 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:slf1_mouse(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 32(gene name synonym)|uniprotkb:BRCT domain-containing protein 1(gene name synonym)|uniprotkb:Protein BRCTx(gene name synonym)|uniprotkb:Slf1(gene name)|psi-mi:Slf1(display_short)|uniprotkb:Ankrd32(gene name synonym)|uniprotkb:Brctd1(gene name synonym)|uniprotkb:Brctx(gene name synonym) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666404|imex:IM-28774-1887 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001357(BRCT)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036420|interpro:IPR036770|interpro:IPR042479|ensembl:ENSMUSG00000021597(gene)|ensembl:ENSMUST00000151524(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_598832.3|refseq:XP_017170840.1|entrezgene/locuslink:105377(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QYHcSM/B1bl5X55rfIcULXJpNzg10090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:DI4f4U29DynR9JX3tXmAlg2cseo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16520 uniprotkb:Q15306 intact:EBI-749503|ensembl:ENSP00000286639 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 psi-mi:batf_human(display_long)|uniprotkb:SF-HT-activated gene 2 protein(gene name synonym)|uniprotkb:BATF(gene name)|psi-mi:BATF(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666412|imex:IM-28774-1425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006390.1|dip:DIP-52482N|ensembl:ENSG00000156127(gene)|ensembl:ENST00000286639(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|mint:Q16520|reactome:R-HSA-6785807|entrezgene/locuslink:10538(identity) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) - crc64:7FD633C6F1963DF4 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rZdG+kauGaMPmB9bp0fV2W0t4lk9606 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rigid:5jG3Ka0xBLoyBNpAYSpV2oXreoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53567 uniprotkb:P18847 intact:EBI-740209|uniprotkb:Q5U052|ensembl:ENSP00000284000|ensembl:ENSP00000466022|ensembl:ENSP00000499062|uniprotkb:B2R946 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:cebpg_human(display_long)|uniprotkb:CEBPG(gene name)|psi-mi:CEBPG(display_short) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666420|imex:IM-28774-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|ensembl:ENSG00000153879(gene)|ensembl:ENST00000284000(transcript)|ensembl:ENST00000585933(transcript)|ensembl:ENST00000652630(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001797.1|refseq:NP_001239225.1|entrezgene/locuslink:1054(identity) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N|entrezgene/locuslink:467(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UneEv6RijykMEaPgr/apEUYxnJI9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rigid:jIg1kStswH+6SJfNVTtr+lfG3w4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53567 uniprotkb:P18848 intact:EBI-740209|uniprotkb:Q5U052|ensembl:ENSP00000284000|ensembl:ENSP00000466022|ensembl:ENSP00000499062|uniprotkb:B2R946 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:cebpg_human(display_long)|uniprotkb:CEBPG(gene name)|psi-mi:CEBPG(display_short) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666428|imex:IM-28774-1889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|ensembl:ENSG00000153879(gene)|ensembl:ENST00000284000(transcript)|ensembl:ENST00000585933(transcript)|ensembl:ENST00000652630(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001797.1|refseq:NP_001239225.1|entrezgene/locuslink:1054(identity) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity) - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UneEv6RijykMEaPgr/apEUYxnJI9606 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:MqEELvWb8k34rsQVeLDUOLVCc8c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8R3P9 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26666349|ensembl:ENSMUSP00000118312|uniprotkb:Q497V2|uniprotkb:Q5XK30|uniprotkb:Q8BHY5|uniprotkb:Q8BQM6|uniprotkb:Q921Y9 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:slf1_mouse(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 32(gene name synonym)|uniprotkb:BRCT domain-containing protein 1(gene name synonym)|uniprotkb:Protein BRCTx(gene name synonym)|uniprotkb:Slf1(gene name)|psi-mi:Slf1(display_short)|uniprotkb:Ankrd32(gene name synonym)|uniprotkb:Brctd1(gene name synonym)|uniprotkb:Brctx(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666396|imex:IM-28774-3165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001357(BRCT)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036420|interpro:IPR036770|interpro:IPR042479|ensembl:ENSMUSG00000021597(gene)|ensembl:ENSMUST00000151524(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_598832.3|refseq:XP_017170840.1|entrezgene/locuslink:105377(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:QYHcSM/B1bl5X55rfIcULXJpNzg10090 rigid:C1D2cvh5v+dW6UtvqHwNpYvq/YM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R3P9 uniprotkb:Q9CYZ8 intact:EBI-26666349|ensembl:ENSMUSP00000118312|uniprotkb:Q497V2|uniprotkb:Q5XK30|uniprotkb:Q8BHY5|uniprotkb:Q8BQM6|uniprotkb:Q921Y9 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:slf1_mouse(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 32(gene name synonym)|uniprotkb:BRCT domain-containing protein 1(gene name synonym)|uniprotkb:Protein BRCTx(gene name synonym)|uniprotkb:Slf1(gene name)|psi-mi:Slf1(display_short)|uniprotkb:Ankrd32(gene name synonym)|uniprotkb:Brctd1(gene name synonym)|uniprotkb:Brctx(gene name synonym) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666388|imex:IM-28774-3163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001357(BRCT)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036420|interpro:IPR036770|interpro:IPR042479|ensembl:ENSMUSG00000021597(gene)|ensembl:ENSMUST00000151524(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_598832.3|refseq:XP_017170840.1|entrezgene/locuslink:105377(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QYHcSM/B1bl5X55rfIcULXJpNzg10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:kTB8PQGw8bHAFnovT/IVl4k9Ing false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91YQ3 uniprotkb:P70662 intact:EBI-26666436|ensembl:ENSMUSP00000044441|uniprotkb:Q3V1F0 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:csdc2_mouse(display_long)|uniprotkb:RNA-binding protein PIPPin(gene name synonym)|uniprotkb:Csdc2(gene name)|psi-mi:Csdc2(display_short)|uniprotkb:Pippin(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666457|imex:IM-28774-971 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019844|ensembl:ENSMUSG00000042109(gene)|ensembl:ENSMUST00000038757(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_663448.2|entrezgene/locuslink:105859(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3RDMDQNwdlrdPdoz0T3SkUCKu/Y10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:JU86wgfgfOfg48GVc6jSIbtOqsY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91YQ3 uniprotkb:Q07279 intact:EBI-26666436|ensembl:ENSMUSP00000044441|uniprotkb:Q3V1F0 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:csdc2_mouse(display_long)|uniprotkb:RNA-binding protein PIPPin(gene name synonym)|uniprotkb:Csdc2(gene name)|psi-mi:Csdc2(display_short)|uniprotkb:Pippin(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666465|imex:IM-28774-973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019844|ensembl:ENSMUSG00000042109(gene)|ensembl:ENSMUST00000038757(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_663448.2|entrezgene/locuslink:105859(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3RDMDQNwdlrdPdoz0T3SkUCKu/Y10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:lUJOaoWjP2BXFhSaHGyo9leg8FI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6NZP6 uniprotkb:P31311 intact:EBI-26666481 intact:EBI-445941|uniprotkb:Q3V026|ensembl:ENSMUSP00000040920 psi-mi:q6nzp6_mouse(display_long)|uniprotkb:Hmgxb3(gene name)|psi-mi:Hmgxb3(display_short) psi-mi:hxa11_mouse(display_long)|uniprotkb:Hoxa11(gene name)|psi-mi:Hoxa11(display_short)|uniprotkb:Hox-1.9(gene name synonym)|uniprotkb:Hoxa-11(gene name synonym)|uniprotkb:Homeobox protein Hox-1.9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666489|imex:IM-28774-2323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598895.2|refseq:XP_017173268.1|interpro:IPR039598|interpro:IPR040648|entrezgene/locuslink:106894(identity) refseq:NP_034580.1|ensembl:ENSMUSG00000038210(gene)|ensembl:ENSMUST00000048026(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010720"(positive regulation of cell development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048589"(developmental growth)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060065"(uterus development)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:15396(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fOy8osi6L3VoXKX4aXIVEdy4+eA10090 rogid:xmuaYwHq6mzn6Qbx/zJIcMkoNsk10090 rigid:JDe/286I3a0GC8QBHdaM6zK0ZDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:Q8IVW6 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-5458329|uniprotkb:O95443|uniprotkb:Q59HC9|uniprotkb:Q6P9C9|ensembl:ENSP00000477878 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:ari3b_human(display_long)|uniprotkb:ARID3B(gene name)|psi-mi:ARID3B(display_short)|uniprotkb:BDP(gene name synonym)|uniprotkb:DRIL2(gene name synonym)|uniprotkb:Bright and dead ringer protein(gene name synonym)|uniprotkb:Bright-like protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666473|imex:IM-28774-2315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) refseq:NP_001294868.1|refseq:NP_006456.1|ensembl:ENSG00000179361(gene)|ensembl:ENST00000622429(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|mint:Q8IVW6|interpro:IPR036431|entrezgene/locuslink:10620(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:wlZYnH9qjM7VzFUtrNLlqJhRXx49606 rigid:1+JW/RN2NYxyu1pg9eb7TV+EXsM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z5J4 uniprotkb:P35638 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666497|imex:IM-28774-2729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:10743(identity) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) - - crc64:31905293FB1FBBE2 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:KQdtqyzWyEbawPIcKpjLvGNQ8vM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z5J4 uniprotkb:P15976 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666505|imex:IM-28774-1891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:10743(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:R1+bC23TefqHR15/bhjmRjNHH90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z5J4 uniprotkb:P08151 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666513|imex:IM-28774-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:10743(identity) refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N|entrezgene/locuslink:2735(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 rigid:V0WmfrYl6V62SGck+lvLcmUOd+4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z5J4 uniprotkb:Q8N653 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666521|imex:IM-28774-1427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:10743(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:TVbX9WzL/QSgTwJg+ZLgKM+QPOs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UMS5 uniprotkb:P17482 intact:EBI-11733241|uniprotkb:Q5VWP7|uniprotkb:Q5VWP8|uniprotkb:Q9BUP2|uniprotkb:Q9H1X8|ensembl:ENSP00000358617|ensembl:ENSP00000377025 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:phtf1_human(display_long)|uniprotkb:PHTF1(gene name)|psi-mi:PHTF1(display_short)|uniprotkb:PHTF(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666529|imex:IM-28774-975 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309971.1|refseq:NP_001309972.1|refseq:NP_001309976.1|refseq:NP_001309977.1|refseq:NP_001309978.1|refseq:NP_001309970.1|refseq:NP_006599.2|ensembl:ENSG00000116793(gene)|ensembl:ENST00000369604(transcript)|ensembl:ENST00000393357(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0016021"(integral component of membrane)|interpro:IPR021980|interpro:IPR039775|entrezgene/locuslink:10745(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XhBJsIuEUeTkTKlP/hbQc6M3v9A9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:mxZLC7jddqYfMdxgoOa+jHtPsiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70191 uniprotkb:P53568 intact:EBI-26666572|ensembl:ENSMUSP00000047771|ensembl:ENSMUSP00000103525|uniprotkb:Q58E51|uniprotkb:Q99NH6 intact:EBI-26666537|ensembl:ENSMUSP00000064963|ensembl:ENSMUSP00000118588 psi-mi:atf5_mouse(display_long)|uniprotkb:Activating transcription factor 5-alpha/beta(gene name synonym)|uniprotkb:BZIP protein ATF7(gene name synonym)|uniprotkb:NAP1(gene name synonym)|uniprotkb:NRIF3-associated protein(gene name synonym)|uniprotkb:Transcription factor ATFx(gene name synonym)|uniprotkb:Transcription factor-like protein ODA-10(gene name synonym)|uniprotkb:Atf5(gene name)|psi-mi:Atf5(display_short)|uniprotkb:Atfx(gene name synonym)|uniprotkb:Nap1(gene name synonym) psi-mi:cebpg_mouse(display_long)|uniprotkb:Granulocyte colony-stimulating factor promoter element 1-binding protein(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding protein 1(gene name synonym)|uniprotkb:Cebpg(gene name)|psi-mi:Cebpg(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666622|imex:IM-28774-2731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021891"(olfactory bulb interneuron development)|ensembl:ENSMUSG00000038539(gene)|ensembl:ENSMUST00000047356(transcript)|ensembl:ENSMUST00000107893(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029855|go:"GO:0021988"(olfactory lobe development)|refseq:NP_109618.1|entrezgene/locuslink:107503(identity) go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSMUSG00000056216(gene)|ensembl:ENSMUST00000070191(transcript)|ensembl:ENSMUST00000130491(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_034014.1|entrezgene/locuslink:12611(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W5N57MdGg9KYWwZP4Ngv4dphL3w10090 rogid:Kl4vhpKHcGIVXh3W05HrerMTCs010090 rigid:G8AXHc55t0BqwV6SeRJ42fAZQEg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZZ3 uniprotkb:P23812 intact:EBI-2255545|uniprotkb:Q8BIV9|uniprotkb:Q8VDP8|ensembl:ENSMUSP00000041627|ensembl:ENSMUSP00000103881 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:wwp1_mouse(display_long)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Wwp1(gene name)|psi-mi:Wwp1(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666630|imex:IM-28774-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796301.2|refseq:NP_001263221.1|ensembl:ENSMUSG00000041058(gene)|ensembl:ENSMUST00000035982(transcript)|ensembl:ENSMUST00000108246(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|reactome:R-MMU-1253288|reactome:R-MMU-2672351|reactome:R-MMU-983168|entrezgene/locuslink:107568(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QIyGeg2WafDTey/CzzDSCZd7rqg10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:poqgxI4BmSTvYCkVFsUN/Sp+H8s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDQ2 uniprotkb:P31245 intact:EBI-3043852|ensembl:ENSMUSP00000060054 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666678|imex:IM-28774-3167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|entrezgene/locuslink:107932(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:KljSe7FsdLo7AGPDStDcn+HkRvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58462 uniprotkb:P97471 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 intact:EBI-5259270|uniprotkb:Q6GTP6|uniprotkb:Q9CW56|ensembl:ENSMUSP00000025393|ensembl:ENSMUSP00000110589 psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:smad4_mouse(display_long)|uniprotkb:Smad4(gene name)|psi-mi:Smad4(display_short)|uniprotkb:Dpc4(gene name synonym)|uniprotkb:Madh4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4 homolog(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666836|imex:IM-28774-3171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) refseq:NP_032566.2|dip:DIP-29718N|ensembl:ENSMUSG00000024515(gene)|ensembl:ENSMUST00000025393(transcript)|ensembl:ENSMUST00000114939(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001822"(kidney development)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003360"(brainstem development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007369"(gastrulation)|go:"GO:0007411"(axon guidance)|go:"GO:0007492"(endoderm development)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031005"(filamin binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042060"(wound healing)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P97471|rcsb pdb:3QSV|reactome:R-MMU-1181150|reactome:R-MMU-1502540|reactome:R-MMU-201451|reactome:R-MMU-2173789|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-5689880|reactome:R-MMU-8941326|reactome:R-MMU-8941855|reactome:R-MMU-9617828|entrezgene/locuslink:17128(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rogid:IJFXHvSWr9ahHMgHAekwlFtH57w10090 rigid:ILKWAW8VPE4uklLewvUm/6Aqak0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q6PDQ2 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666662|imex:IM-28774-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|entrezgene/locuslink:107932(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rigid:QI5pFSOygiTivfzwo+irxY/6XhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15916 uniprotkb:Q15916 intact:EBI-7227791|uniprotkb:A8K8N6|intact:MINT-1193121|ensembl:ENSP00000362763 intact:EBI-7227791|uniprotkb:A8K8N6|intact:MINT-1193121|ensembl:ENSP00000362763 psi-mi:zbtb6_human(display_long)|uniprotkb:ZBTB6(gene name)|psi-mi:ZBTB6(display_short)|uniprotkb:ZNF482(gene name synonym)|uniprotkb:ZID(gene name synonym)|uniprotkb:Zinc finger protein 482(gene name synonym)|uniprotkb:Zinc finger protein with interaction domain(gene name synonym) psi-mi:zbtb6_human(display_long)|uniprotkb:ZBTB6(gene name)|psi-mi:ZBTB6(display_short)|uniprotkb:ZNF482(gene name synonym)|uniprotkb:ZID(gene name synonym)|uniprotkb:Zinc finger protein 482(gene name synonym)|uniprotkb:Zinc finger protein with interaction domain(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666646|imex:IM-28774-2325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006617.1|ensembl:ENSG00000186130(gene)|ensembl:ENST00000373659(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|dip:DIP-2653N|entrezgene/locuslink:10773(identity) refseq:NP_006617.1|ensembl:ENSG00000186130(gene)|ensembl:ENST00000373659(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|dip:DIP-2653N|entrezgene/locuslink:10773(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint function:May be involved in transcriptional regulation|comment:mint|comment:homomint figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LsCfAlD/AsjdyctUz6+jM/ZEZhk9606 rogid:LsCfAlD/AsjdyctUz6+jM/ZEZhk9606 rigid:6K/1CEI4CG7DJBJrdqWG+3DaK6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15326 uniprotkb:P09016 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666638|imex:IM-28774-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1|entrezgene/locuslink:10771(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:uZGSaE28OCFbER6BA3++DJT6QAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDQ2 uniprotkb:Q61545 intact:EBI-3043852|ensembl:ENSMUSP00000060054 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666670|imex:IM-28774-977 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|entrezgene/locuslink:107932(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:udBdGtrXm77QZu7HmEn8CYa7Qf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58462 uniprotkb:P58462 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666820|imex:IM-28774-2329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rigid:ez+z6lSrns/G+Pt2G9J8qD2rsCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y230 uniprotkb:Q9Y265 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666726|imex:IM-28774-1429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N|entrezgene/locuslink:10856(identity) refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N|entrezgene/locuslink:8607(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 rigid:h8BIpL9TZU79niZGIfjVCvZPFq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y230 uniprotkb:Q9Y265 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666718|imex:IM-28774-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N|entrezgene/locuslink:10856(identity) refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N|entrezgene/locuslink:8607(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 rigid:h8BIpL9TZU79niZGIfjVCvZPFq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CQ39 uniprotkb:Q07279 intact:EBI-6260960|ensembl:ENSMUSP00000032429|ensembl:ENSMUSP00000145512|uniprotkb:Q921I5 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:med21_mouse(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:Srb7(gene name synonym)|uniprotkb:Surb7(gene name synonym)|uniprotkb:Med21(gene name)|psi-mi:Med21(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666710|imex:IM-28774-3169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030291(gene)|ensembl:ENSMUST00000032429(transcript)|ensembl:ENSMUST00000204040(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:6W1S|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_079591.1|dip:DIP-59522N|entrezgene/locuslink:108098(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4a1HoRbOTd2Nm/gDGbidH5rrMbg10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:Kw9cNRUpDv2pZKx6c6fwadLB9gw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDQ2 uniprotkb:Q3U4B1 intact:EBI-3043852|ensembl:ENSMUSP00000060054 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666702|imex:IM-28774-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|entrezgene/locuslink:107932(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:FV/2k0bripaQ5cGr9iU1TIPN4cs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDQ2 uniprotkb:Q3UA06 intact:EBI-3043852|ensembl:ENSMUSP00000060054 intact:EBI-308990|uniprotkb:A0JNT8|uniprotkb:Q05CL4|uniprotkb:Q3UQG6|uniprotkb:Q9CWW8|ensembl:ENSMUSP00000022053 psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:pch2_mouse(display_long)|uniprotkb:Trip13(gene name)|psi-mi:Trip13(display_short)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Pch2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666694|imex:IM-28774-2327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|entrezgene/locuslink:107932(identity) refseq:NP_081458.1|ensembl:ENSMUSG00000021569(gene)|ensembl:ENSMUST00000022053(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|entrezgene/locuslink:69716(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rogid:VyTQoaPmHJT2nvfJdg00WZVnhkI10090 rigid:fwJ9nErd/cTtVRoEWenrQlp36+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58462 uniprotkb:O35973 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666844|imex:IM-28774-1431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rigid:3RJ/XL5Kbv2ToVfnm8sAezlhstw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58462 uniprotkb:O54943 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 intact:EBI-1266779|uniprotkb:O54954 psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666852|imex:IM-28774-2733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rigid:M6vbQSZVzUyFHXMKPFyn3zr452s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTU0 uniprotkb:P58462 intact:EBI-8339791|intact:MINT-4107441|uniprotkb:Q6A023|uniprotkb:Q80WA8|ensembl:ENSMUSP00000047308 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 psi-mi:phf2_mouse(display_long)|uniprotkb:Phf2(gene name)|psi-mi:Phf2(display_short)|uniprotkb:GRC5(gene name synonym)|uniprotkb:Kiaa0662(gene name synonym)|uniprotkb:PHD finger protein 2(gene name synonym) psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666860|imex:IM-28774-1433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035208.2|ensembl:ENSMUSG00000038025(gene)|ensembl:ENSMUST00000035540(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035574"(histone H4-K20 demethylation)|go:"GO:0035575"(histone H4-methyl-lysine-20 demethylase activity)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|mint:Q9WTU0|reactome:R-MMU-3214842|entrezgene/locuslink:18676(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2RoS6FXstspu+TN1DwCkVySJlUI10090 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rigid:MC85Vhe1P/whLkTwk81Yd1837j4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58462 uniprotkb:P15806 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666868|imex:IM-28774-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:rUaTTuDrC0XZvDKg3fTwCcAd9EU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDQ2 uniprotkb:Q07279 intact:EBI-3043852|ensembl:ENSMUSP00000060054 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666686|imex:IM-28774-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N|entrezgene/locuslink:107932(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:akQu7U2sjzgHcHQ8Brd4i4MSYb0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZL8 uniprotkb:O55203 intact:EBI-16728185|ensembl:ENSMUSP00000124862|ensembl:ENSMUSP00000125335|ensembl:ENSMUSP00000125589|ensembl:ENSMUSP00000145048 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lmo3_mouse(display_long)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Lmo3(gene name)|psi-mi:Lmo3(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666932|imex:IM-28774-981 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030226(gene)|ensembl:ENSMUST00000161450(transcript)|ensembl:ENSMUST00000162772(transcript)|ensembl:ENSMUST00000163024(transcript)|ensembl:ENSMUST00000203435(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_997105.1|refseq:XP_006505403.1|refseq:XP_006505404.1|refseq:XP_006505405.1|refseq:XP_006505407.1|refseq:XP_011239433.1|refseq:XP_011239434.1|refseq:XP_011239435.1|refseq:XP_017176802.1|entrezgene/locuslink:109593(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:9q47R+sOVCuxjc3GOqe/1sRzY7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZL8 uniprotkb:P70662 intact:EBI-16728185|ensembl:ENSMUSP00000124862|ensembl:ENSMUSP00000125335|ensembl:ENSMUSP00000125589|ensembl:ENSMUSP00000145048 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lmo3_mouse(display_long)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Lmo3(gene name)|psi-mi:Lmo3(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666924|imex:IM-28774-1437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030226(gene)|ensembl:ENSMUST00000161450(transcript)|ensembl:ENSMUST00000162772(transcript)|ensembl:ENSMUST00000163024(transcript)|ensembl:ENSMUST00000203435(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_997105.1|refseq:XP_006505403.1|refseq:XP_006505404.1|refseq:XP_006505405.1|refseq:XP_006505407.1|refseq:XP_011239433.1|refseq:XP_011239434.1|refseq:XP_011239435.1|refseq:XP_017176802.1|entrezgene/locuslink:109593(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:XAVTMnNQ7EaqpZnXAS7h4CHPVro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15287 uniprotkb:P09016 intact:EBI-395959|uniprotkb:A8K1P0|uniprotkb:B4DDU8|uniprotkb:B4DZU7|uniprotkb:B7ZA17|uniprotkb:O75308|uniprotkb:Q32P25|uniprotkb:Q8WY42|uniprotkb:Q9NYG3|ensembl:ENSP00000301730|ensembl:ENSP00000315859|ensembl:ENSP00000380275|ensembl:ENSP00000457723|ensembl:ENSP00000457820 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:rnps1_human(display_long)|uniprotkb:SR-related protein LDC2(gene name synonym)|uniprotkb:RNPS1(gene name)|psi-mi:RNPS1(display_short)|uniprotkb:LDC2(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666916|imex:IM-28774-979 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006702.1|refseq:NP_542161.1|refseq:NP_001273554.1|refseq:NP_001273555.1|refseq:NP_001273556.1|ensembl:ENSG00000205937(gene)|ensembl:ENST00000301730(transcript)|ensembl:ENST00000320225(transcript)|ensembl:ENST00000397086(transcript)|ensembl:ENST00000565678(transcript)|ensembl:ENST00000568631(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q15287|rcsb pdb:4A8X|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:XP_005255105.1|refseq:XP_005255106.1|refseq:XP_016878363.1|dip:DIP-32943N|entrezgene/locuslink:10921(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nANu/nh/pD/F6dYE2Sa28OegPGs9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:8AVI44gBHqbBqKEHZE2n3BpRXQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BGJ0 uniprotkb:P15806 intact:EBI-26666876|ensembl:ENSMUSP00000047615|uniprotkb:Q3TV63|uniprotkb:Q8BMB7 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:zdh15_mouse(display_long)|uniprotkb:Acyltransferase ZDHHC15(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 15(gene name synonym)|uniprotkb:Zdhhc15(gene name)|psi-mi:Zdhhc15(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666908|imex:IM-28774-1435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033906(gene)|ensembl:ENSMUST00000042070(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0062237"(protein localization to postsynapse)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|go:"GO:0140450"(protein targeting to Golgi apparatus)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001594(Zinc finger, DHHC-type)|refseq:NP_780567.1|entrezgene/locuslink:108672(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jH+pF/BqSaECH0tZWEW3DusdBZE10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:IclXhqUZyCOtHqHUdfQXAPduRUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZL8 uniprotkb:Q9CYZ8 intact:EBI-16728185|ensembl:ENSMUSP00000124862|ensembl:ENSMUSP00000125335|ensembl:ENSMUSP00000125589|ensembl:ENSMUSP00000145048 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:lmo3_mouse(display_long)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Lmo3(gene name)|psi-mi:Lmo3(display_short) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666977|imex:IM-28774-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030226(gene)|ensembl:ENSMUST00000161450(transcript)|ensembl:ENSMUST00000162772(transcript)|ensembl:ENSMUST00000163024(transcript)|ensembl:ENSMUST00000203435(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_997105.1|refseq:XP_006505403.1|refseq:XP_006505404.1|refseq:XP_006505405.1|refseq:XP_006505407.1|refseq:XP_011239433.1|refseq:XP_011239434.1|refseq:XP_011239435.1|refseq:XP_017176802.1|entrezgene/locuslink:109593(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:l78S0q+b/IFm+D80+F0nF73nw/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZL8 uniprotkb:Q62282 intact:EBI-16728185|ensembl:ENSMUSP00000124862|ensembl:ENSMUSP00000125335|ensembl:ENSMUSP00000125589|ensembl:ENSMUSP00000145048 intact:EBI-26666949|ensembl:ENSMUSP00000030124 psi-mi:lmo3_mouse(display_long)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Lmo3(gene name)|psi-mi:Lmo3(display_short) psi-mi:tal2_mouse(display_long)|uniprotkb:Tal2(gene name)|psi-mi:Tal2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666969|imex:IM-28774-1415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030226(gene)|ensembl:ENSMUST00000161450(transcript)|ensembl:ENSMUST00000162772(transcript)|ensembl:ENSMUST00000163024(transcript)|ensembl:ENSMUST00000203435(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_997105.1|refseq:XP_006505403.1|refseq:XP_006505404.1|refseq:XP_006505405.1|refseq:XP_006505407.1|refseq:XP_011239433.1|refseq:XP_011239434.1|refseq:XP_011239435.1|refseq:XP_017176802.1|entrezgene/locuslink:109593(identity) ensembl:ENSMUSG00000028417(gene)|ensembl:ENSMUST00000030124(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|refseq:NP_033343.1|entrezgene/locuslink:21350(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc10090 rogid:tDWYKvhprGUoqYYZRC7pdjc2I/E10090 rigid:qJ2aK3JO0ggO58d2xAY0nkdY0LY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22091 uniprotkb:Q8BZL8 intact:EBI-8006437|intact:MINT-2567683|ensembl:ENSMUSP00000030489|ensembl:ENSMUSP00000124983|ensembl:ENSMUSP00000125202 intact:EBI-16728185|ensembl:ENSMUSP00000124862|ensembl:ENSMUSP00000125335|ensembl:ENSMUSP00000125589|ensembl:ENSMUSP00000145048 psi-mi:tal1_mouse(display_long)|uniprotkb:Tal1(gene name)|psi-mi:Tal1(display_short)|uniprotkb:Scl(gene name synonym)|uniprotkb:Tal-1(gene name synonym)|uniprotkb:Stem cell protein(gene name synonym) psi-mi:lmo3_mouse(display_long)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Lmo3(gene name)|psi-mi:Lmo3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26666941|imex:IM-28774-2331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035657.1|refseq:NP_001274317.1|refseq:XP_006502973.1|refseq:XP_006502975.1|refseq:XP_006502976.1|refseq:XP_006502977.1|refseq:XP_006502978.1|refseq:XP_006502979.1|dip:DIP-42839N|ensembl:ENSMUSG00000028717(gene)|ensembl:ENSMUST00000030489(transcript)|ensembl:ENSMUST00000161601(transcript)|ensembl:ENSMUST00000162489(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007626"(locomotory behavior)|go:"GO:0019899"(enzyme binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045799"(positive regulation of chromatin assembly or disassembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048699"(generation of neurons)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060217"(hemangioblast cell differentiation)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060375"(regulation of mast cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|mint:P22091|reactome:R-MMU-8939236|entrezgene/locuslink:21349(identity) ensembl:ENSMUSG00000030226(gene)|ensembl:ENSMUST00000161450(transcript)|ensembl:ENSMUST00000162772(transcript)|ensembl:ENSMUST00000163024(transcript)|ensembl:ENSMUST00000203435(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_997105.1|refseq:XP_006505403.1|refseq:XP_006505404.1|refseq:XP_006505405.1|refseq:XP_006505407.1|refseq:XP_011239433.1|refseq:XP_011239434.1|refseq:XP_011239435.1|refseq:XP_017176802.1|entrezgene/locuslink:109593(identity) - comment:mint|function:Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation|function:Involved in chromosomal translocation in leukemic stem-cells - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:lFDGEWJ65/G4+uXxjEQ/gMZbKq010090 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc10090 rigid:VeqyTxtydV0PDpkQQBs9OC8Gu4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0M0 uniprotkb:Q9Y6K9 intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667323|imex:IM-28774-1443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|entrezgene/locuslink:11059(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:/8eVHH58UDfa2Jet0NhxcAT+3lg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0M0 uniprotkb:Q8N653 intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667315|imex:IM-28774-2743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|entrezgene/locuslink:11059(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:Mx9Y2N+8DL8PBpXX0eeuOqolztk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0M0 uniprotkb:Q8N653 intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667307|imex:IM-28774-1897 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|entrezgene/locuslink:11059(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:Mx9Y2N+8DL8PBpXX0eeuOqolztk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0M0 uniprotkb:P42226 intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667299|imex:IM-28774-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|entrezgene/locuslink:11059(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:xd04WyQTqNGNOYoF6Cb9NRDvsTg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0M0 uniprotkb:P61457 intact:EBI-742157|uniprotkb:O00307|uniprotkb:Q96BP4|ensembl:ENSP00000265428|ensembl:ENSP00000427793|uniprotkb:Q5YLC1 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:wwp1_human(display_long)|uniprotkb:WWP1(gene name)|psi-mi:WWP1(display_short)|uniprotkb:WW domain-containing protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 5(gene name synonym)|uniprotkb:TGIF-interacting ubiquitin ligase 1(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase WWP1(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667291|imex:IM-28774-1441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008944.1|interpro:IPR035892|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR035983|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR036020|mint:Q9H0M0|rcsb pdb:1ND7|rcsb pdb:2OP7|rcsb pdb:5HPS|rcsb pdb:5HPT|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|rcsb pdb:6J1X|rcsb pdb:6J1Y|reactome:R-HSA-1253288|reactome:R-HSA-2672351|reactome:R-HSA-8939902|reactome:R-HSA-983168|interpro:IPR024928|ensembl:ENSG00000123124(gene)|ensembl:ENST00000265428(transcript)|ensembl:ENST00000517970(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_005250817.1|entrezgene/locuslink:11059(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a+aRHHhwu3pCkmlkDNqcN1PJ7LI9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:OmsqUNZl9rL+VBYazU4QlG+tlzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:P55771 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667283|imex:IM-28774-987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:xugwSdW7LAxpjWYX4tVEE6NiS5I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:O95475 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-21949028|uniprotkb:Q6NT42|uniprotkb:Q9P1X8|ensembl:ENSP00000328596 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:six6_human(display_long)|uniprotkb:Homeodomain protein OPTX2(gene name synonym)|uniprotkb:Optic homeobox 2(gene name synonym)|uniprotkb:Sine oculis homeobox homolog 6(gene name synonym)|uniprotkb:SIX6(gene name)|psi-mi:SIX6(display_short)|uniprotkb:OPTX2(gene name synonym)|uniprotkb:SIX9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667275|imex:IM-28774-3187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_031400.2|ensembl:ENSG00000184302(gene)|ensembl:ENST00000327720(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR031701|interpro:IPR032947|entrezgene/locuslink:4990(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:MAfhX8IzpQVaOPaFUdREWDO0Zko9606 rigid:Uun1b0zP8CTewl9gqi086c5WDTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:P18848 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667267|imex:IM-28774-2741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity) - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:gybpr/4Snd1kHNYG7lIEhmpk+sA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:O15525 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-713514|ensembl:ENSP00000350369|ensembl:ENSP00000376173 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:mafg_human(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog G(gene name synonym)|uniprotkb:MAFG(gene name)|psi-mi:MAFG(display_short)|uniprotkb:hMAF(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667259|imex:IM-28774-3185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) go:"GO:0042802"(identical protein binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR028551|mint:O15525|reactome:R-HSA-983231|go:"GO:0042127"(regulation of cell population proliferation)|ensembl:ENSG00000197063(gene)|ensembl:ENST00000357736(transcript)|ensembl:ENST00000392366(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030534"(adult behavior)|go:"GO:0030641"(regulation of cellular pH)|refseq:NP_002350.1|refseq:NP_116100.2|refseq:XP_011521880.1|entrezgene/locuslink:4097(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:mPgx9ZadT4ndfQg/hmancGYbyc89606 rigid:/oAzHxxISDcpnxXuWdfjlKglfaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:O43248 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667251|imex:IM-28774-3183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:cbUDIln8bFUQkC0uqj4HGDlYBKI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:P31274 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667243|imex:IM-28774-2333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:veuKfUQk/VSf0ktY6NTV8UBcc5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20719 uniprotkb:Q9UNN4 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667235|imex:IM-28774-3181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719|entrezgene/locuslink:3202(identity) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rigid:rrOR5cxvoaxw6NG6bSaFg2ErUic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:O43763 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667227|imex:IM-28774-3179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:wtH9aiA4x2U5KTJEYcK+qZBDmGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:Q04743 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-399831|uniprotkb:Q96NN8|uniprotkb:Q9BQF4|uniprotkb:G3V305|ensembl:ENSP00000450962 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:emx2_human(display_long)|uniprotkb:EMX2(gene name)|psi-mi:EMX2(display_short)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667219|imex:IM-28774-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_001159396.1|refseq:NP_004089.1|ensembl:ENSG00000170370(gene)|ensembl:ENST00000553456(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:2018(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:+b7ChE+6RlzUb0sr/8vnDFtFy2c9606 rigid:z+qhTYuAJcb1/KQbb6Y9zbpYPG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:Q04741 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667211|imex:IM-28774-985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rigid:vlGt9QuyzC5X0MTRiO//YThfkMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:Q15744 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667203|imex:IM-28774-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:X/1AQrEkjrmWXNe4PVl7w296Vq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNN4 uniprotkb:Q9NP66 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78 psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667195|imex:IM-28774-2739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606 rigid:apuC9/sKmlfnBCx8ufPystBW9Vk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z148 uniprotkb:Q05BA5 intact:EBI-444966|uniprotkb:Q6PE08|uniprotkb:Q8K4R6|uniprotkb:Q8K4R7|uniprotkb:Q9Z149|uniprotkb:A2CG75|ensembl:ENSMUSP00000013931 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:ehmt2_mouse(display_long)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Ehmt2(gene name)|psi-mi:Ehmt2(display_short)|uniprotkb:G9a(gene name synonym)|uniprotkb:Ng36(gene name synonym)|uniprotkb:Bat8(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667187|imex:IM-28774-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_665829.1|refseq:NP_671493.1|refseq:NP_001273502.1|refseq:NP_001273504.1|ensembl:ENSMUSG00000013787(gene)|ensembl:ENSMUST00000013931(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007281"(germ cell development)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|interpro:IPR043550|mint:Q9Z148|reactome:R-MMU-2559582|reactome:R-MMU-3214841|reactome:R-MMU-6804760|reactome:R-MMU-73762|reactome:R-MMU-8953750|dip:DIP-31916N|entrezgene/locuslink:110147(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SN94zTs0cmZHuzgtVLjSTDtfOAM10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:UToPZ0vJ80WkqRhjxTH9QuBq1pg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TNV0 uniprotkb:O55144 intact:EBI-8340579|uniprotkb:Q8BZV6|uniprotkb:Q80VC5|intact:MINT-1868135|ensembl:ENSMUSP00000021807 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:dek_mouse(display_long)|uniprotkb:Dek(gene name)|psi-mi:Dek(display_short) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667179|imex:IM-28774-3177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080176.2|ensembl:ENSMUSG00000021377(gene)|ensembl:ENSMUST00000021807(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:Q7TNV0|reactome:R-MMU-5250924|reactome:R-MMU-8864260|entrezgene/locuslink:110052(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - comment:mint|function:May have a function in the nucleus - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vzAw0iLJp4Iq3k447Ks/10bngUg10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:L+iySGwyi9EyZgL8aJwqEzSeRhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:S4R1L6 uniprotkb:Q9CY99 intact:EBI-26667038|ensembl:ENSMUSP00000138271 intact:EBI-26667123|ensembl:ENSMUSP00000036049 psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:q9cy99_mouse(display_long)|uniprotkb:Zfp623(gene name)|psi-mi:Zfp623(display_short)|uniprotkb:Bsg5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667139|imex:IM-28774-1895 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) ensembl:ENSMUSG00000050846(gene)|ensembl:ENSMUST00000037260(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_084475.1|refseq:XP_006521606.1|entrezgene/locuslink:78834(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rogid:csX1yq9+n1O5S+UXLiT9ZayDGKw10090 rigid:iD3vtqZY9TyrQI9pPzuIG5HP6wM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:S4R1L6 uniprotkb:E9Q5M9 intact:EBI-26667038|ensembl:ENSMUSP00000138271 intact:EBI-26667100|ensembl:ENSMUSP00000101907 psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:e9q5m9_mouse(display_long)|uniprotkb:Zfp688(gene name)|psi-mi:Zfp688(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667115|imex:IM-28774-3175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) ensembl:ENSMUSG00000045251(gene)|ensembl:ENSMUST00000106300(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_081275.3|entrezgene/locuslink:69234(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rogid:JGkcbc9bHkO9/iyS1N+ukA9HHWY10090 rigid:8PYNgjmWFiOC4JeXH804Ih0NQNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:S4R1L6 uniprotkb:Q07230 intact:EBI-26667038|ensembl:ENSMUSP00000138271 intact:EBI-26665895|ensembl:ENSMUSP00000042321 psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:zsca2_mouse(display_long)|uniprotkb:Zinc finger protein 29(gene name synonym)|uniprotkb:Zscan2(gene name)|psi-mi:Zscan2(display_short)|uniprotkb:Zfp-29(gene name synonym)|uniprotkb:Zfp29(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667092|imex:IM-28774-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|rcsb pdb:2I13|ensembl:ENSMUSG00000038797(gene)|ensembl:ENSMUST00000044115(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|refseq:NP_033579.1|refseq:XP_006540868.1|refseq:XP_006540869.1|refseq:XP_006540870.1|refseq:XP_006540871.1|refseq:XP_006540872.1|refseq:XP_006540873.1|refseq:XP_006540874.1|refseq:XP_006540875.1|entrezgene/locuslink:22691(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rogid:TKkA1qeOjBvBBvqNNMoIA8zG87w10090 rigid:Dh1pMs00Ybw73NfJqVqh33RT5A0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:S4R1L6 uniprotkb:S4R1L6 intact:EBI-26667038|ensembl:ENSMUSP00000138271 intact:EBI-26667038|ensembl:ENSMUSP00000138271 psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667076|imex:IM-28774-1439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rigid:sggLJ2Ifu/htoGd8wMmvUsFyqvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:S4R1L6 uniprotkb:Q6PD29 intact:EBI-26667038|ensembl:ENSMUSP00000138271 intact:EBI-3044009|ensembl:ENSMUSP00000110238|uniprotkb:Q3U4K1|uniprotkb:Q8BWH6 psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:zn513_mouse(display_long)|uniprotkb:Znf513(gene name)|psi-mi:Znf513(display_short)|uniprotkb:Zfp513(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667068|imex:IM-28774-983 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) ensembl:ENSMUSG00000043059(gene)|ensembl:ENSMUST00000114590(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001171372.1|refseq:NP_780520.3|refseq:XP_006503720.2|entrezgene/locuslink:101023(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rogid:Uv2jsMClXB89tOJP1vn8uzWMQUw10090 rigid:lUQnIeRdnPNZxb9J3TFWZM03ymw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:S4R1L6 uniprotkb:Q6PD29 intact:EBI-26667038|ensembl:ENSMUSP00000138271 intact:EBI-3044009|ensembl:ENSMUSP00000110238|uniprotkb:Q3U4K1|uniprotkb:Q8BWH6 psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:zn513_mouse(display_long)|uniprotkb:Znf513(gene name)|psi-mi:Znf513(display_short)|uniprotkb:Zfp513(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667060|imex:IM-28774-1893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) ensembl:ENSMUSG00000043059(gene)|ensembl:ENSMUST00000114590(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001171372.1|refseq:NP_780520.3|refseq:XP_006503720.2|entrezgene/locuslink:101023(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rogid:Uv2jsMClXB89tOJP1vn8uzWMQUw10090 rigid:lUQnIeRdnPNZxb9J3TFWZM03ymw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924W9 uniprotkb:Q9CYZ8 intact:EBI-26666985|ensembl:ENSMUSP00000037079 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:rbtn1_mouse(display_long)|uniprotkb:Cysteine-rich protein TTG-1(gene name synonym)|uniprotkb:LIM domain only protein 1(gene name synonym)|uniprotkb:T-cell translocation protein 1(gene name synonym)|uniprotkb:Lmo1(gene name)|psi-mi:Lmo1(display_short)|uniprotkb:Rbtn1(gene name synonym)|uniprotkb:Rhom1(gene name synonym)|uniprotkb:Ttg1(gene name synonym) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667030|imex:IM-28774-2735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046013"(regulation of T cell homeostatic proliferation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-8939236|ensembl:ENSMUSG00000036111(gene)|ensembl:ENSMUST00000036992(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|refseq:NP_001289134.1|refseq:NP_001289135.1|refseq:NP_476514.1|refseq:XP_006507258.1|entrezgene/locuslink:109594(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:O1odhYb3e4GOcK2nCkAd5yO8UE810090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:kVW89wj8Z5LG1xNqyChuflbkNLU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924W9 uniprotkb:Q62282 intact:EBI-26666985|ensembl:ENSMUSP00000037079 intact:EBI-26666949|ensembl:ENSMUSP00000030124 psi-mi:rbtn1_mouse(display_long)|uniprotkb:Cysteine-rich protein TTG-1(gene name synonym)|uniprotkb:LIM domain only protein 1(gene name synonym)|uniprotkb:T-cell translocation protein 1(gene name synonym)|uniprotkb:Lmo1(gene name)|psi-mi:Lmo1(display_short)|uniprotkb:Rbtn1(gene name synonym)|uniprotkb:Rhom1(gene name synonym)|uniprotkb:Ttg1(gene name synonym) psi-mi:tal2_mouse(display_long)|uniprotkb:Tal2(gene name)|psi-mi:Tal2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667022|imex:IM-28774-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046013"(regulation of T cell homeostatic proliferation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-8939236|ensembl:ENSMUSG00000036111(gene)|ensembl:ENSMUST00000036992(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|refseq:NP_001289134.1|refseq:NP_001289135.1|refseq:NP_476514.1|refseq:XP_006507258.1|entrezgene/locuslink:109594(identity) ensembl:ENSMUSG00000028417(gene)|ensembl:ENSMUST00000030124(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|refseq:NP_033343.1|entrezgene/locuslink:21350(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:O1odhYb3e4GOcK2nCkAd5yO8UE810090 rogid:tDWYKvhprGUoqYYZRC7pdjc2I/E10090 rigid:m4T7BdIXbztBGk/nbwHnqDBSM9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924W9 uniprotkb:O55203 intact:EBI-26666985|ensembl:ENSMUSP00000037079 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:rbtn1_mouse(display_long)|uniprotkb:Cysteine-rich protein TTG-1(gene name synonym)|uniprotkb:LIM domain only protein 1(gene name synonym)|uniprotkb:T-cell translocation protein 1(gene name synonym)|uniprotkb:Lmo1(gene name)|psi-mi:Lmo1(display_short)|uniprotkb:Rbtn1(gene name synonym)|uniprotkb:Rhom1(gene name synonym)|uniprotkb:Ttg1(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667014|imex:IM-28774-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046013"(regulation of T cell homeostatic proliferation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-8939236|ensembl:ENSMUSG00000036111(gene)|ensembl:ENSMUST00000036992(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|refseq:NP_001289134.1|refseq:NP_001289135.1|refseq:NP_476514.1|refseq:XP_006507258.1|entrezgene/locuslink:109594(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:O1odhYb3e4GOcK2nCkAd5yO8UE810090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:tPEQ4g8egJuig+rLmbD3eZojwSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924W9 uniprotkb:P70662 intact:EBI-26666985|ensembl:ENSMUSP00000037079 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:rbtn1_mouse(display_long)|uniprotkb:Cysteine-rich protein TTG-1(gene name synonym)|uniprotkb:LIM domain only protein 1(gene name synonym)|uniprotkb:T-cell translocation protein 1(gene name synonym)|uniprotkb:Lmo1(gene name)|psi-mi:Lmo1(display_short)|uniprotkb:Rbtn1(gene name synonym)|uniprotkb:Rhom1(gene name synonym)|uniprotkb:Ttg1(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667006|imex:IM-28774-3173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046013"(regulation of T cell homeostatic proliferation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-8939236|ensembl:ENSMUSG00000036111(gene)|ensembl:ENSMUST00000036992(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|refseq:NP_001289134.1|refseq:NP_001289135.1|refseq:NP_476514.1|refseq:XP_006507258.1|entrezgene/locuslink:109594(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:O1odhYb3e4GOcK2nCkAd5yO8UE810090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:AHvEgZxedogVyRJkRQVKvQyJwpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58462 uniprotkb:Q9WVB3 intact:EBI-26666734|ensembl:ENSMUSP00000073953|ensembl:ENSMUSP00000108948|uniprotkb:Q6P221|uniprotkb:Q8C5V2|uniprotkb:Q8CCD9 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:foxp1_mouse(display_long)|uniprotkb:Forkhead-related transcription factor 1(gene name synonym)|uniprotkb:Foxp1(gene name)|psi-mi:Foxp1(display_short) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667504|imex:IM-28774-3193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|ensembl:ENSMUSG00000030067(gene)|ensembl:ENSMUST00000074346(transcript)|ensembl:ENSMUST00000113322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR036388|interpro:IPR036390|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061140"(lung secretory cell differentiation)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0072359"(circulatory system development)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901249"(regulation of lung goblet cell differentiation)|go:"GO:1901250"(negative regulation of lung goblet cell differentiation)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|refseq:NP_001184250.1|refseq:NP_001184251.1|refseq:NP_444432.1|refseq:XP_006505385.1|refseq:XP_006505386.1|entrezgene/locuslink:108655(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wFQ+8AYcZDv8HquvQtRIcyEl4AQ10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:stI6najJY9Y3EVucg4z4oCAh2hg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKU8 uniprotkb:O55203 intact:EBI-26667331|ensembl:ENSMUSP00000028003|ensembl:ENSMUSP00000107008 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lmx1a_mouse(display_long)|uniprotkb:LIM/homeobox protein 1.1(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1A(gene name synonym)|uniprotkb:Lmx1a(gene name)|psi-mi:Lmx1a(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667384|imex:IM-28774-1445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026686(gene)|ensembl:ENSMUST00000028003(transcript)|ensembl:ENSMUST00000111377(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0042048"(olfactory behavior)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042688|refseq:NP_387501.1|refseq:XP_006496674.1|refseq:XP_017177173.1|entrezgene/locuslink:110648(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nsXtWb3E0uW1mP9Iw1+yvLmVPuk10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:SYM3rVOTqb+yaHo1/PcJ4+k/EhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKU8 uniprotkb:Q9CYZ8 intact:EBI-26667331|ensembl:ENSMUSP00000028003|ensembl:ENSMUSP00000107008 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:lmx1a_mouse(display_long)|uniprotkb:LIM/homeobox protein 1.1(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1A(gene name synonym)|uniprotkb:Lmx1a(gene name)|psi-mi:Lmx1a(display_short) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667392|imex:IM-28774-3189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026686(gene)|ensembl:ENSMUST00000028003(transcript)|ensembl:ENSMUST00000111377(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0042048"(olfactory behavior)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042688|refseq:NP_387501.1|refseq:XP_006496674.1|refseq:XP_017177173.1|entrezgene/locuslink:110648(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nsXtWb3E0uW1mP9Iw1+yvLmVPuk10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:BKE66II8IRhi5t3X6ZrN2VyMA9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D8M7 uniprotkb:Q9JKU8 intact:EBI-8339310|intact:MINT-4127642|uniprotkb:Q99LV5|uniprotkb:E9QLI2 intact:EBI-26667331|ensembl:ENSMUSP00000028003|ensembl:ENSMUSP00000107008 psi-mi:phf10_mouse(display_long)|uniprotkb:Phf10(gene name)|psi-mi:Phf10(display_short)|uniprotkb:Baf45a(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:lmx1a_mouse(display_long)|uniprotkb:LIM/homeobox protein 1.1(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1A(gene name synonym)|uniprotkb:Lmx1a(gene name)|psi-mi:Lmx1a(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667400|imex:IM-28774-3191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR019787|refseq:NP_077212.3|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR038045|mint:Q9D8M7|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|entrezgene/locuslink:72057(identity) ensembl:ENSMUSG00000026686(gene)|ensembl:ENSMUST00000028003(transcript)|ensembl:ENSMUST00000111377(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0042048"(olfactory behavior)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042688|refseq:NP_387501.1|refseq:XP_006496674.1|refseq:XP_017177173.1|entrezgene/locuslink:110648(identity) - comment:mint|function:May act as a transcription regulator - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:udf/gKP7bnl292/Hb/Mwf9QOwFY10090 rogid:nsXtWb3E0uW1mP9Iw1+yvLmVPuk10090 rigid:mlkhktARK3ZOunqVtajGZdBvzos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14802 uniprotkb:Q01844 intact:EBI-2515113|ensembl:ENSP00000361446|uniprotkb:Q8TCW5|uniprotkb:Q8IW34 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:rpc1_human(display_long)|uniprotkb:POLR3A(gene name)|psi-mi:POLR3A(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III 155 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667440|imex:IM-28774-1447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000148606(gene)|ensembl:ENST00000372371(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|interpro:IPR042102|mint:O14802|rcsb pdb:7A6H|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|rcsb pdb:7AE1|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_008986.2|entrezgene/locuslink:11128(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aIkROXC0f3CXTeRzAvW+lyXSmTE9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:2xYT7WfDiQMiusq9+QIZcbUTHoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14802 uniprotkb:P61457 intact:EBI-2515113|ensembl:ENSP00000361446|uniprotkb:Q8TCW5|uniprotkb:Q8IW34 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:rpc1_human(display_long)|uniprotkb:POLR3A(gene name)|psi-mi:POLR3A(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III 155 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667448|imex:IM-28774-2747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000148606(gene)|ensembl:ENST00000372371(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|interpro:IPR042102|mint:O14802|rcsb pdb:7A6H|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|rcsb pdb:7AE1|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_008986.2|entrezgene/locuslink:11128(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aIkROXC0f3CXTeRzAvW+lyXSmTE9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:LeRrjjzpcryNPuTqXjES9yXIFWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14802 uniprotkb:Q9Y6K9 intact:EBI-2515113|ensembl:ENSP00000361446|uniprotkb:Q8TCW5|uniprotkb:Q8IW34 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:rpc1_human(display_long)|uniprotkb:POLR3A(gene name)|psi-mi:POLR3A(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III 155 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667456|imex:IM-28774-1449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000148606(gene)|ensembl:ENST00000372371(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|interpro:IPR042102|mint:O14802|rcsb pdb:7A6H|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|rcsb pdb:7AE1|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_008986.2|entrezgene/locuslink:11128(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aIkROXC0f3CXTeRzAvW+lyXSmTE9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:XT4kxH1C2qnR12uw8bjnNHiOyf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43365 uniprotkb:Q13610 intact:EBI-8643838|ensembl:ENSP00000324884|ensembl:ENSP00000379640|ensembl:ENSP00000484411|uniprotkb:A4D181|intact:MINT-8163379 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 psi-mi:hxa3_human(display_long)|uniprotkb:HOXA3(gene name)|psi-mi:HOXA3(display_short)|uniprotkb:HOX1E(gene name synonym)|uniprotkb:Homeobox protein Hox-1E(gene name synonym) psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667464|imex:IM-28774-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105997(gene)|ensembl:ENST00000317201(transcript)|ensembl:ENST00000396352(transcript)|ensembl:ENST00000612286(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0010467"(gene expression)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0048538"(thymus development)|go:"GO:0048645"(animal organ formation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0071837"(HMG box domain binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011513645.1|refseq:XP_005249787.1|refseq:XP_005249788.1|refseq:XP_005249789.1|refseq:NP_109377.1|refseq:NP_705895.1|refseq:XP_006715778.1|entrezgene/locuslink:3200(identity) refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610|entrezgene/locuslink:11137(identity) - comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7gP6b03wtjUhsVpcwdjdrUtQj4Y9606 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 rigid:s6Az6nqZW6TfEwPQIn+oxXRKW/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13610 uniprotkb:P23511 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 intact:EBI-389739|uniprotkb:Q8IXU0|ensembl:ENSP00000345702 psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:nfya_human(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667472|imex:IM-28774-2749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610|entrezgene/locuslink:11137(identity) refseq:NP_002496.1|refseq:NP_068351.1|ensembl:ENSG00000001167(gene)|ensembl:ENST00000341376(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001289(CCAAT-binding transcription factor, subunit B)|interpro:IPR018362|rcsb pdb:4AWL|rcsb pdb:6QMP|rcsb pdb:6QMQ|rcsb pdb:6QMS|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|entrezgene/locuslink:4800(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 rogid:ZzEyS17rD3653YFSvnBoGdl1T3s9606 rigid:roYEs4pc1YJ3hdJKMFKK7Dnu/cY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NRM2 uniprotkb:Q16531 intact:EBI-949305|ensembl:ENSP00000354501|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667480|imex:IM-28774-2339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198839(gene)|ensembl:ENST00000361822(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_068834.2|entrezgene/locuslink:11179(identity) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N|entrezgene/locuslink:1642(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:sIJvXB8ows7UxCxYSccqybeJi3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95905 uniprotkb:Q01844 intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667488|imex:IM-28774-1899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1|entrezgene/locuslink:11319(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:1vJRotegDYxJaruzS6/IF+7JO1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZY9 uniprotkb:Q9Y6K9 intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667408|imex:IM-28774-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300|entrezgene/locuslink:11074(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:ootWHop9bGhogNsCH/l44fH7T28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKN5 uniprotkb:Q9UKN5 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667416|imex:IM-28774-2335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3|entrezgene/locuslink:11108(identity) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3|entrezgene/locuslink:11108(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rigid:tMruC8BO/r2SRm8gVTLJn7dMV7c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKN5 uniprotkb:Q04741 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667432|imex:IM-28774-2337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3|entrezgene/locuslink:11108(identity) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rigid:Ymkf0zX19fSJBN3nuTgBOu3kjak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKU8 uniprotkb:P70662 intact:EBI-26667331|ensembl:ENSMUSP00000028003|ensembl:ENSMUSP00000107008 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lmx1a_mouse(display_long)|uniprotkb:LIM/homeobox protein 1.1(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1A(gene name synonym)|uniprotkb:Lmx1a(gene name)|psi-mi:Lmx1a(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667376|imex:IM-28774-2745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026686(gene)|ensembl:ENSMUST00000028003(transcript)|ensembl:ENSMUST00000111377(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0042048"(olfactory behavior)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042688|refseq:NP_387501.1|refseq:XP_006496674.1|refseq:XP_017177173.1|entrezgene/locuslink:110648(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nsXtWb3E0uW1mP9Iw1+yvLmVPuk10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:3B3xvR4hlyijP0X//y+1W8k3w+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6T264 uniprotkb:Q9WVB3 intact:EBI-7650924|ensembl:ENSMUSP00000059210|uniprotkb:Q8BIU5|uniprotkb:Q505D8|uniprotkb:Q6PDK3|uniprotkb:Q5SUC2|uniprotkb:Q6ZQG5|uniprotkb:Q8R3T0|intact:MINT-8375705 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:maml1_mouse(display_long)|uniprotkb:Maml1(gene name)|psi-mi:Maml1(display_short)|uniprotkb:Kiaa0200(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667496|imex:IM-28774-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050567(gene)|ensembl:ENSMUST00000059458(transcript)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0060928"(atrioventricular node cell development)|interpro:IPR019082|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0010831"(positive regulation of myotube differentiation)|refseq:NP_780543.2|entrezgene/locuslink:103806(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Us4w80GoyIJvEFn21oB6J1MqGHg10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:B0sx7RaTAsEs9B/sp1y4zHbLaeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35137 uniprotkb:Q9WVB3 intact:EBI-26667512|ensembl:ENSMUSP00000047962 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667552|imex:IM-28774-989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:oe+FoZGmq3JlfAZETZxbdEX+cuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61545 uniprotkb:Q9WVB3 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667568|imex:IM-28774-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:JemdjkdYjGP8SRgxoU2Z2ObPPM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:Q9WVB3 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667687|imex:IM-28774-2343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:rmxJSdgEKQCPt6NTGqHo0V5I4i8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q9WVB3 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667679|imex:IM-28774-1453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:w6iB4CX298S2Iol+Kvds6T70nHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3X904 uniprotkb:Q9WVB3 intact:EBI-26667657|ensembl:ENSMUSP00000033731 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667671|imex:IM-28774-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:RBZwtIJ7SKL+Hn+1E5iNz+VyKwo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q9WVB3 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667560|imex:IM-28774-1901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:eoEAKVGzLc2LS2JD28R/hIB2TpY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:Q9WVB3 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667641|imex:IM-28774-2751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:ULY5iuC6zfpnimEJtkM0845nLmQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05BA5 uniprotkb:Q9WVB3 intact:EBI-5745783|ensembl:ENSMUSP00000085416 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667633|imex:IM-28774-1451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:9OXWc0KmSCo7Mb//bRzjOJ5YYkE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09027 uniprotkb:Q9WVB3 intact:EBI-26667584|ensembl:ENSMUSP00000044809|ensembl:ENSMUSP00000107613|ensembl:ENSMUSP00000107614|uniprotkb:Q3UUD3 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:hxd3_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.1(gene name synonym)|uniprotkb:Homeobox protein MH-19(gene name synonym)|uniprotkb:Hoxd3(gene name)|psi-mi:Hoxd3(display_short)|uniprotkb:Hox-4.1(gene name synonym)|uniprotkb:Hoxd-3(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667625|imex:IM-28774-1903 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000079277(gene)|ensembl:ENSMUST00000047830(transcript)|ensembl:ENSMUST00000111982(transcript)|ensembl:ENSMUST00000111983(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|go:"GO:0051216"(cartilage development)|refseq:NP_034598.2|entrezgene/locuslink:15434(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:o47Zd1IWzICvHRhhGN4cN2AQ+r010090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:2fUnYzlFRc/e7kZaYbQ5W0/JmPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31245 uniprotkb:Q9WVB3 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667576|imex:IM-28774-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:DAlZJcyw2vKRi7NpkmpDV48Nris false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:Q9WVB3 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667649|imex:IM-28774-2341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:PyHkwmOgg9xZRRSOQTs0TeoOpkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:Q9WVB3 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667714|imex:IM-28774-2345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:IibGn2iov75P4t5N5F7jUmuJFOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9WVB3 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667722|imex:IM-28774-2347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:uoTAlUAKTtL8Or2YnZbwoTPwC68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:Q9WVB3 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667730|imex:IM-28774-3195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:6S9e+y5vxT0T+ftRsOItVfSBw5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:Q9WVB3 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667738|imex:IM-28774-1905 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:T0EY0Un+WOd4Mil+XftE+pVxank false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q925B0 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-77397|uniprotkb:Q0ZHI4|uniprotkb:Q2HYJ1|ensembl:ENSMUSP00000092951 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:pawr_mouse(display_long)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667746|imex:IM-28774-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) refseq:NP_473397.1|ensembl:ENSMUSG00000035873(gene)|ensembl:ENSMUST00000095313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR026117|entrezgene/locuslink:114774(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:Gk3XStiqqgG3pPQCINRrZtP3XPk10090 rigid:P/13QBryWXbeMhra/tFAypqtWHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q925B0 uniprotkb:P28705 intact:EBI-77397|uniprotkb:Q0ZHI4|uniprotkb:Q2HYJ1|ensembl:ENSMUSP00000092951 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 psi-mi:pawr_mouse(display_long)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym) psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667798|imex:IM-28774-1455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_473397.1|ensembl:ENSMUSG00000035873(gene)|ensembl:ENSMUST00000095313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR026117|entrezgene/locuslink:114774(identity) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Gk3XStiqqgG3pPQCINRrZtP3XPk10090 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rigid:Qmz7RIppamEkQP8j+NDGbHprNnc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91V10 uniprotkb:P50220 intact:EBI-26667806|ensembl:ENSMUSP00000039088 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 psi-mi:vsx1_mouse(display_long)|uniprotkb:Homeodomain protein RINX(gene name synonym)|uniprotkb:Retinal inner nuclear layer homeobox protein(gene name synonym)|uniprotkb:Transcription factor VSX1(gene name synonym)|uniprotkb:Vsx1(gene name)|psi-mi:Vsx1(display_short)|uniprotkb:Rinx(gene name synonym) psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667830|imex:IM-28774-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033080(gene)|ensembl:ENSMUST00000046095(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007601"(visual perception)|go:"GO:0042551"(neuron maturation)|go:"GO:0048666"(neuron development)|go:"GO:0060040"(retinal bipolar neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR023339|go:"GO:0050896"(response to stimulus)|refseq:NP_473409.1|entrezgene/locuslink:114889(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:I84WV1j6sA78RaMd5oKZCZps9k410090 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rigid:4i4daL3e6DI5PtaUT9Rh9HPwwJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08915 uniprotkb:P30561 intact:EBI-6935014|ensembl:ENSMUSP00000025767|ensembl:ENSMUSP00000113807|intact:MINT-3374208|uniprotkb:Q3UJM2 intact:EBI-78863|uniprotkb:Q8QZX6|uniprotkb:Q8R4S3|uniprotkb:Q99P79|uniprotkb:Q9QVY1 psi-mi:aip_mouse(display_long)|uniprotkb:Aip(gene name)|psi-mi:Aip(display_short)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym) psi-mi:ahr_mouse(display_long)|uniprotkb:Ahr(gene name)|psi-mi:Ahr(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667838|imex:IM-28774-991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006531704.2|refseq:XP_006531705.1|ensembl:ENSMUSG00000024847(gene)|ensembl:ENSMUST00000025767(transcript)|ensembl:ENSMUST00000117831(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036004"(GAF domain binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031208|interpro:IPR039663|mint:O08915|reactome:R-MMU-8937144|refseq:NP_001263213.1|refseq:NP_057875.1|entrezgene/locuslink:11632(identity) refseq:NP_038492.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001889"(liver development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003243"(circumferential growth involved in left ventricle morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008015"(blood circulation)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010693"(negative regulation of alkaline phosphatase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015643"(toxic substance binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0034753"(nuclear aryl hydrocarbon receptor complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048536"(spleen development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060420"(regulation of heart growth)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0060841"(venous blood vessel development)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061009"(common bile duct development)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1904682"(cellular response to 3-methylcholanthrene)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:4M4X|rcsb pdb:5V0L|dip:DIP-222N|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144|entrezgene/locuslink:11622(identity) - comment:mint|function:"May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mBCvlXDje9eercrujdkrGx7iKCQ10090 rogid:N+pBJ492yievt6CTflKb8oQgqfU10090 rigid:2GLJI0+uMGPxFScY8gzdTvSiSxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35137 uniprotkb:O35137 intact:EBI-26667512|ensembl:ENSMUSP00000047962 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667846|imex:IM-28774-1907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:6KfBD7mkKLyt9s5ikuEZgut4+EU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:Q96NX9 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-20842710|ensembl:ENSP00000362217|uniprotkb:B1AJV3|uniprotkb:B4DQG3|uniprotkb:Q8NAY3|uniprotkb:Q8ND17|uniprotkb:Q96N55 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:dach2_human(display_long)|uniprotkb:DACH2(gene name)|psi-mi:DACH2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667862|imex:IM-28774-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) ensembl:ENSG00000126733(gene)|ensembl:ENST00000373125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR037000|refseq:NP_001132986.1|refseq:NP_001132987.1|refseq:NP_444511.1|refseq:XP_016884745.1|entrezgene/locuslink:117154(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:hRuAzD+2XxsyYH75/g0IM8tOAWY9606 rigid:csr6BoARJejJ3mAHrvSEI8OR9fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q920Q8 uniprotkb:O08856 intact:EBI-643239|uniprotkb:Q06BK6|uniprotkb:Q3TXI1|uniprotkb:Q3UJE3|uniprotkb:Q3UJS1|uniprotkb:Q3UKH9|uniprotkb:Q3UMK9|uniprotkb:Q6ZQ34|uniprotkb:Q99KN0|uniprotkb:Q9D978|ensembl:ENSMUSP00000023918 intact:EBI-647129|uniprotkb:Q3TXY9|ensembl:ENSMUSP00000091163 psi-mi:ns1bp_mouse(display_long)|uniprotkb:Kelch family protein Nd1-L(gene name synonym)|uniprotkb:ND1-L2(gene name synonym)|uniprotkb:Nd1-S(gene name synonym)|uniprotkb:Ivns1abp(gene name)|psi-mi:Ivns1abp(display_short)|uniprotkb:Kiaa0850(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:Nd1L(gene name synonym)|uniprotkb:Nd1S(gene name synonym)|uniprotkb:Ns1(gene name synonym)|uniprotkb:Ns1bp(gene name synonym) psi-mi:ell_mouse(display_long)|uniprotkb:Eleven-nineteen lysine-rich leukemia protein(gene name synonym)|uniprotkb:Ell(gene name)|psi-mi:Ell(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667870|imex:IM-28774-3199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034600.1|refseq:NP_001034601.1|refseq:NP_473443.2|ensembl:ENSMUSG00000023150(gene)|ensembl:ENSMUST00000023918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|entrezgene/locuslink:117198(identity) refseq:NP_031950.2|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0035363"(histone locus body)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR019464|interpro:IPR031176|interpro:IPR031184|interpro:IPR036390|interpro:IPR042065|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|ensembl:ENSMUSG00000070002(gene)|ensembl:ENSMUST00000093454(transcript)|entrezgene/locuslink:13716(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j5/XawL9H4va/BB/HXbIeItP7MY10090 rogid:4GxbT6h5yA/Vv63XVYRjP9nQYAE10090 rigid:UNigARszrkybS8pB1IZISCMmnNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q920Q8 uniprotkb:P15806 intact:EBI-643239|uniprotkb:Q06BK6|uniprotkb:Q3TXI1|uniprotkb:Q3UJE3|uniprotkb:Q3UJS1|uniprotkb:Q3UKH9|uniprotkb:Q3UMK9|uniprotkb:Q6ZQ34|uniprotkb:Q99KN0|uniprotkb:Q9D978|ensembl:ENSMUSP00000023918 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:ns1bp_mouse(display_long)|uniprotkb:Kelch family protein Nd1-L(gene name synonym)|uniprotkb:ND1-L2(gene name synonym)|uniprotkb:Nd1-S(gene name synonym)|uniprotkb:Ivns1abp(gene name)|psi-mi:Ivns1abp(display_short)|uniprotkb:Kiaa0850(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:Nd1L(gene name synonym)|uniprotkb:Nd1S(gene name synonym)|uniprotkb:Ns1(gene name synonym)|uniprotkb:Ns1bp(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667878|imex:IM-28774-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034600.1|refseq:NP_001034601.1|refseq:NP_473443.2|ensembl:ENSMUSG00000023150(gene)|ensembl:ENSMUST00000023918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|entrezgene/locuslink:117198(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j5/XawL9H4va/BB/HXbIeItP7MY10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:xsT8QFWxWUVA0J8XNMpS0Z3+TK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q920Q8 uniprotkb:G3X904 intact:EBI-643239|uniprotkb:Q06BK6|uniprotkb:Q3TXI1|uniprotkb:Q3UJE3|uniprotkb:Q3UJS1|uniprotkb:Q3UKH9|uniprotkb:Q3UMK9|uniprotkb:Q6ZQ34|uniprotkb:Q99KN0|uniprotkb:Q9D978|ensembl:ENSMUSP00000023918 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:ns1bp_mouse(display_long)|uniprotkb:Kelch family protein Nd1-L(gene name synonym)|uniprotkb:ND1-L2(gene name synonym)|uniprotkb:Nd1-S(gene name synonym)|uniprotkb:Ivns1abp(gene name)|psi-mi:Ivns1abp(display_short)|uniprotkb:Kiaa0850(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:Nd1L(gene name synonym)|uniprotkb:Nd1S(gene name synonym)|uniprotkb:Ns1(gene name synonym)|uniprotkb:Ns1bp(gene name synonym) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667886|imex:IM-28774-993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034600.1|refseq:NP_001034601.1|refseq:NP_473443.2|ensembl:ENSMUSG00000023150(gene)|ensembl:ENSMUST00000023918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|entrezgene/locuslink:117198(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j5/XawL9H4va/BB/HXbIeItP7MY10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:aNUMascKQ1iZnqANaFSefToBYKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q920Q8 uniprotkb:Q9WUL8 intact:EBI-643239|uniprotkb:Q06BK6|uniprotkb:Q3TXI1|uniprotkb:Q3UJE3|uniprotkb:Q3UJS1|uniprotkb:Q3UKH9|uniprotkb:Q3UMK9|uniprotkb:Q6ZQ34|uniprotkb:Q99KN0|uniprotkb:Q9D978|ensembl:ENSMUSP00000023918 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:ns1bp_mouse(display_long)|uniprotkb:Kelch family protein Nd1-L(gene name synonym)|uniprotkb:ND1-L2(gene name synonym)|uniprotkb:Nd1-S(gene name synonym)|uniprotkb:Ivns1abp(gene name)|psi-mi:Ivns1abp(display_short)|uniprotkb:Kiaa0850(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:Nd1L(gene name synonym)|uniprotkb:Nd1S(gene name synonym)|uniprotkb:Ns1(gene name synonym)|uniprotkb:Ns1bp(gene name synonym) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667894|imex:IM-28774-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034600.1|refseq:NP_001034601.1|refseq:NP_473443.2|ensembl:ENSMUSG00000023150(gene)|ensembl:ENSMUST00000023918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|entrezgene/locuslink:117198(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j5/XawL9H4va/BB/HXbIeItP7MY10090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:m6XMnFWhKd0/nMCEE6AJMF9v/TE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q920Q8 uniprotkb:Q8CGW9 intact:EBI-643239|uniprotkb:Q06BK6|uniprotkb:Q3TXI1|uniprotkb:Q3UJE3|uniprotkb:Q3UJS1|uniprotkb:Q3UKH9|uniprotkb:Q3UMK9|uniprotkb:Q6ZQ34|uniprotkb:Q99KN0|uniprotkb:Q9D978|ensembl:ENSMUSP00000023918 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 psi-mi:ns1bp_mouse(display_long)|uniprotkb:Kelch family protein Nd1-L(gene name synonym)|uniprotkb:ND1-L2(gene name synonym)|uniprotkb:Nd1-S(gene name synonym)|uniprotkb:Ivns1abp(gene name)|psi-mi:Ivns1abp(display_short)|uniprotkb:Kiaa0850(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:Nd1L(gene name synonym)|uniprotkb:Nd1S(gene name synonym)|uniprotkb:Ns1(gene name synonym)|uniprotkb:Ns1bp(gene name synonym) psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667931|imex:IM-28774-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034600.1|refseq:NP_001034601.1|refseq:NP_473443.2|ensembl:ENSMUSG00000023150(gene)|ensembl:ENSMUST00000023918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008380"(RNA splicing)|go:"GO:0009615"(response to virus)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|entrezgene/locuslink:117198(identity) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j5/XawL9H4va/BB/HXbIeItP7MY10090 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rigid:sTO0yWFtFhZ91L2APnrXdflBEPU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5VYY1 uniprotkb:O75177 intact:EBI-21574866|uniprotkb:B2R9Y7|uniprotkb:Q8WU06|ensembl:ENSP00000360998 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:anr22_human(display_long)|uniprotkb:ANKRD22(gene name)|psi-mi:ANKRD22(display_short) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667939|imex:IM-28774-2349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653191.2|ensembl:ENSG00000152766(gene)|ensembl:ENST00000371930(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042802|entrezgene/locuslink:118932(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bf7ej2FDxhMChTrtwccvVyZNAO09606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:QK+eMkOptZY9hgCCnqqE6mewxC0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WYK2 uniprotkb:P15336 intact:EBI-1248415|uniprotkb:O95430|uniprotkb:Q9UIE4|uniprotkb:J3KN58|ensembl:ENSP00000399587|ensembl:ENSP00000409787|ensembl:ENSP00000415558|ensembl:ENSP00000498745 intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110|ensembl:ENSP00000376327 psi-mi:jdp2_human(display_long)|uniprotkb:JDP2(gene name)|psi-mi:JDP2(display_short) psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668078|imex:IM-28774-1457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128519.1|refseq:NP_001128520.1|refseq:NP_001128521.1|refseq:NP_569736.1|refseq:XP_005267389.1|refseq:XP_016876463.1|refseq:XP_016876464.1|refseq:XP_016876462.1|refseq:XP_016876461.1|ensembl:ENSG00000140044(gene)|ensembl:ENST00000419727(transcript)|ensembl:ENST00000435893(transcript)|ensembl:ENST00000437176(transcript)|ensembl:ENST00000651602(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|mint:Q8WYK2|entrezgene/locuslink:122953(identity) refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|ensembl:ENST00000345739|ensembl:ENSP00000340576|ensembl:ENSP00000376327|ensembl:ENST00000409499|ensembl:ENSP00000386282|ensembl:ENST00000409635|ensembl:ENSP00000387093|ensembl:ENST00000409833|ensembl:ENSP00000386526|ensembl:ENST00000426833|ensembl:ENSP00000407911|ensembl:ENSP00000264110|refseq:NP_001243021.1|refseq:NP_001243022.1|ensembl:ENSG00000115966(gene)|ensembl:ENST00000264110(transcript)|ensembl:ENST00000392544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032915"(positive regulation of transforming growth factor beta2 production)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902562"(H4 histone acetyltransferase complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR029836|interpro:IPR036236|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044013"(H2B histone acetyltransferase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097186"(amelogenesis)|dip:DIP-632N|entrezgene/locuslink:1386(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GlvR4o3M6B1Y3wFpzc8nA46amW49606 rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606 rigid:HiBWebMZ+Mv7mhGbBDCLWFAFtDM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WYK2 uniprotkb:P32780 intact:EBI-1248415|uniprotkb:O95430|uniprotkb:Q9UIE4|uniprotkb:J3KN58|ensembl:ENSP00000399587|ensembl:ENSP00000409787|ensembl:ENSP00000415558|ensembl:ENSP00000498745 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:jdp2_human(display_long)|uniprotkb:JDP2(gene name)|psi-mi:JDP2(display_short) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668086|imex:IM-28774-2351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128519.1|refseq:NP_001128520.1|refseq:NP_001128521.1|refseq:NP_569736.1|refseq:XP_005267389.1|refseq:XP_016876463.1|refseq:XP_016876464.1|refseq:XP_016876462.1|refseq:XP_016876461.1|ensembl:ENSG00000140044(gene)|ensembl:ENST00000419727(transcript)|ensembl:ENST00000435893(transcript)|ensembl:ENST00000437176(transcript)|ensembl:ENST00000651602(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|mint:Q8WYK2|entrezgene/locuslink:122953(identity) refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N|entrezgene/locuslink:2965(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GlvR4o3M6B1Y3wFpzc8nA46amW49606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:pcSGVAdHCOi/7p8QEZRiVqBrp08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WYK2 uniprotkb:P17275 intact:EBI-1248415|uniprotkb:O95430|uniprotkb:Q9UIE4|uniprotkb:J3KN58|ensembl:ENSP00000399587|ensembl:ENSP00000409787|ensembl:ENSP00000415558|ensembl:ENSP00000498745 intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 psi-mi:jdp2_human(display_long)|uniprotkb:JDP2(gene name)|psi-mi:JDP2(display_short) psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668094|imex:IM-28774-995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128519.1|refseq:NP_001128520.1|refseq:NP_001128521.1|refseq:NP_569736.1|refseq:XP_005267389.1|refseq:XP_016876463.1|refseq:XP_016876464.1|refseq:XP_016876462.1|refseq:XP_016876461.1|ensembl:ENSG00000140044(gene)|ensembl:ENST00000419727(transcript)|ensembl:ENST00000435893(transcript)|ensembl:ENST00000437176(transcript)|ensembl:ENST00000651602(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|mint:Q8WYK2|entrezgene/locuslink:122953(identity) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N|entrezgene/locuslink:3726(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GlvR4o3M6B1Y3wFpzc8nA46amW49606 rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 rigid:glJIQnKlLw0i/8BhpB/m/rAb81E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61909 uniprotkb:P48985 intact:EBI-309458|ensembl:ENSMUSP00000095856 intact:EBI-15659000|ensembl:ENSMUSP00000098903 psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:atoh1_mouse(display_long)|uniprotkb:Atoh1(gene name)|psi-mi:Atoh1(display_short)|uniprotkb:Ath1(gene name synonym)|uniprotkb:Helix-loop-helix protein mATH-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668102|imex:IM-28774-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) ensembl:ENSMUSG00000073043(gene)|ensembl:ENSMUST00000101351(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042667"(auditory receptor cell fate specification)|go:"GO:0042668"(auditory receptor cell fate determination)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045609"(positive regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000982"(positive regulation of inner ear receptor cell differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032661|interpro:IPR036638|refseq:NP_031526.1|dip:DIP-46434N|entrezgene/locuslink:11921(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rogid:XKphKMUuUsB080XF/5hgtjY097E10090 rigid:Iu0I1kzHg2ykhYHtA+0JNTlEzDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07424 uniprotkb:O35137 intact:EBI-26668214|ensembl:ENSMUSP00000033689 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:cdx4_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)|uniprotkb:Cdx4(gene name)|psi-mi:Cdx4(display_short)|uniprotkb:Cdx-4(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668245|imex:IM-28774-997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031326(gene)|ensembl:ENSMUST00000033689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_031700.1|entrezgene/locuslink:12592(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZygM/NoxCumicSJlDzHtwO/L33410090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:uWTYpab2ZOcAiw5Fcaf4UFzT2WE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61909 uniprotkb:O09105 intact:EBI-309458|ensembl:ENSMUSP00000095856 intact:EBI-26668110|ensembl:ENSMUSP00000051379 psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:ndf4_mouse(display_long)|uniprotkb:Helix-loop-helix protein mATH-3(gene name synonym)|uniprotkb:Protein atonal homolog 3(gene name synonym)|uniprotkb:Neurod4(gene name)|psi-mi:Neurod4(display_short)|uniprotkb:Ath3(gene name synonym)|uniprotkb:Atoh3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668142|imex:IM-28774-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) ensembl:ENSMUSG00000048015(gene)|ensembl:ENSMUST00000061571(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048666"(neuron development)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|interpro:IPR022575|interpro:IPR032651|interpro:IPR036638|refseq:NP_001316418.1|refseq:NP_001316419.1|refseq:NP_031527.1|entrezgene/locuslink:11923(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rogid:cTS7d7Vi51qGXr1bHpEfYYSYebA10090 rigid:Vf5F/d9TMHjkxwiG4gSyGHrGGNE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43241 uniprotkb:O35137 intact:EBI-26668158|ensembl:ENSMUSP00000031650 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:cdx2_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 2(gene name synonym)|uniprotkb:Cdx2(gene name)|psi-mi:Cdx2(display_short)|uniprotkb:Cdx-2(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668206|imex:IM-28774-2753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029646(gene)|ensembl:ENSMUST00000031650(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0060711"(labyrinthine layer development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_031699.2|entrezgene/locuslink:12591(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XpCK7ehS+3cgrG8vncU1t2kkpQ10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:VS5UlNX8asIaAB05BhzCP0ri6Bs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18111 uniprotkb:O35137 intact:EBI-21005290|ensembl:ENSMUSP00000025521|uniprotkb:Q8VCF7 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:cdx1_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 1(gene name synonym)|uniprotkb:Cdx1(gene name)|psi-mi:Cdx1(display_short)|uniprotkb:Cdx-1(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668150|imex:IM-28774-2353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060349"(bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000024619(gene)|ensembl:ENSMUST00000025521(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|refseq:NP_034010.3|entrezgene/locuslink:12590(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Rzc2qIxNozTifZX/rvuUx8uc6lU10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:DXfgtcdsjwvSrKQZeM6Is9Q2AbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q8IYI8 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-726439|uniprotkb:Q8N1R9|ensembl:ENSP00000305373 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:zn440_human(display_long)|uniprotkb:ZNF440(gene name)|psi-mi:ZNF440(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668261|imex:IM-28774-1909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_689570.2|ensembl:ENSG00000171295(gene)|ensembl:ENST00000304060(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:126070(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:dzzz5oi/OuwhFq33wNMBdzM9p5E9606 rigid:cEq9l0PQhoiYiajXGXV8K5FNuiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08785 uniprotkb:Q9WTL8 intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939 intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9 psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short) psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668269|imex:IM-28774-1911 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1|entrezgene/locuslink:12753(identity) refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8|entrezgene/locuslink:11865(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090 rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090 rigid:rR6pjRMS7ztqZs2acls+5QZ2epA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N8E2 uniprotkb:Q8N8E2 intact:EBI-10279993|uniprotkb:Q86UZ3|uniprotkb:B7WP71|uniprotkb:Q3ZCU1|uniprotkb:A8K3S5|uniprotkb:Q8NDL8|uniprotkb:Q68CJ1|uniprotkb:Q96ML3|intact:EBI-28970619|ensembl:ENSP00000318373 intact:EBI-10279993|uniprotkb:Q86UZ3|uniprotkb:B7WP71|uniprotkb:Q3ZCU1|uniprotkb:A8K3S5|uniprotkb:Q8NDL8|uniprotkb:Q68CJ1|uniprotkb:Q96ML3|intact:EBI-28970619|ensembl:ENSP00000318373 psi-mi:zn513_human(display_long)|uniprotkb:ZNF513(gene name)|psi-mi:ZNF513(display_short) psi-mi:zn513_human(display_long)|uniprotkb:ZNF513(gene name)|psi-mi:ZNF513(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668277|imex:IM-28774-2755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000318373|ensembl:ENST00000407879|ensembl:ENSP00000384874|refseq:NP_001188388.1|refseq:NP_653232.3|refseq:XP_005264199.1|refseq:XP_005264200.1|ensembl:ENSG00000163795(gene)|ensembl:ENST00000323703(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:130557(identity) ensembl:ENSP00000318373|ensembl:ENST00000407879|ensembl:ENSP00000384874|refseq:NP_001188388.1|refseq:NP_653232.3|refseq:XP_005264199.1|refseq:XP_005264200.1|ensembl:ENSG00000163795(gene)|ensembl:ENST00000323703(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:130557(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MMEJhQrXKOTRNB7d66GD7NyfIwo9606 rogid:MMEJhQrXKOTRNB7d66GD7NyfIwo9606 rigid:aCtpFVFbP+4fzpubs1QPDhsVP1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N8E2 uniprotkb:Q8IYH5 intact:EBI-10279993|uniprotkb:Q86UZ3|uniprotkb:B7WP71|uniprotkb:Q3ZCU1|uniprotkb:A8K3S5|uniprotkb:Q8NDL8|uniprotkb:Q68CJ1|uniprotkb:Q96ML3|intact:EBI-28970619|ensembl:ENSP00000318373 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:zn513_human(display_long)|uniprotkb:ZNF513(gene name)|psi-mi:ZNF513(display_short) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668293|imex:IM-28774-999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000318373|ensembl:ENST00000407879|ensembl:ENSP00000384874|refseq:NP_001188388.1|refseq:NP_653232.3|refseq:XP_005264199.1|refseq:XP_005264200.1|ensembl:ENSG00000163795(gene)|ensembl:ENST00000323703(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:130557(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MMEJhQrXKOTRNB7d66GD7NyfIwo9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:Yn34kTSLUPCAmqzCLrEFLz7KSqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYI8 uniprotkb:P55771 intact:EBI-726439|uniprotkb:Q8N1R9|ensembl:ENSP00000305373 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:zn440_human(display_long)|uniprotkb:ZNF440(gene name)|psi-mi:ZNF440(display_short) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668253|imex:IM-28774-1459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689570.2|ensembl:ENSG00000171295(gene)|ensembl:ENST00000304060(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:126070(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dzzz5oi/OuwhFq33wNMBdzM9p5E9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:vDBUU9NBc+3yJyXi9N96VfLhtDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N8E2 uniprotkb:Q9NTW7 intact:EBI-10279993|uniprotkb:Q86UZ3|uniprotkb:B7WP71|uniprotkb:Q3ZCU1|uniprotkb:A8K3S5|uniprotkb:Q8NDL8|uniprotkb:Q68CJ1|uniprotkb:Q96ML3|intact:EBI-28970619|ensembl:ENSP00000318373 intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5 psi-mi:zn513_human(display_long)|uniprotkb:ZNF513(gene name)|psi-mi:ZNF513(display_short) psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668309|imex:IM-28774-2757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000318373|ensembl:ENST00000407879|ensembl:ENSP00000384874|refseq:NP_001188388.1|refseq:NP_653232.3|refseq:XP_005264199.1|refseq:XP_005264200.1|ensembl:ENSG00000163795(gene)|ensembl:ENST00000323703(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:130557(identity) refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MMEJhQrXKOTRNB7d66GD7NyfIwo9606 rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606 rigid:9JrK2iafuZQN/x9JYliPKTtKLm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70445 uniprotkb:P61458 intact:EBI-1790207|uniprotkb:A2VCQ1|ensembl:ENSMUSP00000027393 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:bard1_mouse(display_long)|uniprotkb:Bard1(gene name)|psi-mi:Bard1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BARD1(gene name synonym) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668317|imex:IM-28774-3203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031551.1|ensembl:ENSMUSG00000026196(gene)|ensembl:ENSMUST00000027393(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020683|interpro:IPR036420|interpro:IPR036770|interpro:IPR039503|entrezgene/locuslink:12021(identity) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) - - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+RBAGZwtpOQhhdwNe/cV6qehoSw10090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rigid:B7py1Nnp5KItEatd31V6vOJ2G28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:P23950 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-11298268|ensembl:ENSMUSP00000021552|ensembl:ENSMUSP00000127522 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:tisb_mouse(display_long)|uniprotkb:Zfp36l1(gene name)|psi-mi:Zfp36l1(display_short)|uniprotkb:Brf1(gene name synonym)|uniprotkb:Butyrate response factor 1(gene name synonym)|uniprotkb:Tis11b(gene name synonym)|uniprotkb:TPA-induced sequence 11b(gene name synonym)|uniprotkb:Zinc finger protein 36, C3H1 type-like 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668325|imex:IM-28774-2355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) refseq:NP_031590.1|ensembl:ENSMUSG00000021127(gene)|ensembl:ENSMUST00000021552(transcript)|ensembl:ENSMUST00000165114(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003342"(proepicardium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0021915"(neural tube development)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051028"(mRNA transport)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0097403"(cellular response to raffinose)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901991"(negative regulation of mitotic cell cycle phase transition)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR007635(Tis11B like protein, N-terminal)|interpro:IPR036855|reactome:R-MMU-450385|entrezgene/locuslink:12192(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:J8C46e6RLS5Kg/TEuCTbdeFLQAk10090 rigid:cHM/TuGEZFJLX3rZgfNwfBDlsC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:P61458 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668333|imex:IM-28774-2759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rigid:lGc4f70pIC1tySk9uP/xHE2AL2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N8E2 uniprotkb:Q9NTW7 intact:EBI-10279993|uniprotkb:Q86UZ3|uniprotkb:B7WP71|uniprotkb:Q3ZCU1|uniprotkb:A8K3S5|uniprotkb:Q8NDL8|uniprotkb:Q68CJ1|uniprotkb:Q96ML3|intact:EBI-28970619|ensembl:ENSP00000318373 intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5 psi-mi:zn513_human(display_long)|uniprotkb:ZNF513(gene name)|psi-mi:ZNF513(display_short) psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668301|imex:IM-28774-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000318373|ensembl:ENST00000407879|ensembl:ENSP00000384874|refseq:NP_001188388.1|refseq:NP_653232.3|refseq:XP_005264199.1|refseq:XP_005264200.1|ensembl:ENSG00000163795(gene)|ensembl:ENST00000323703(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:130557(identity) refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MMEJhQrXKOTRNB7d66GD7NyfIwo9606 rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606 rigid:9JrK2iafuZQN/x9JYliPKTtKLm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q69ZU8 uniprotkb:O55144 intact:EBI-16354269|ensembl:ENSMUSP00000041300|ensembl:ENSMUSP00000081801|ensembl:ENSMUSP00000081802|uniprotkb:A2ANZ0|uniprotkb:Q6P1A8|uniprotkb:Q8VHD9 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:ankr6_mouse(display_long)|uniprotkb:Ankrd6(gene name)|psi-mi:Ankrd6(display_short)|uniprotkb:Diversin(gene name synonym)|uniprotkb:Kiaa0957(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668689|imex:IM-28774-2365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040183(gene)|ensembl:ENSMUST00000035719(transcript)|ensembl:ENSMUST00000084749(transcript)|ensembl:ENSMUST00000084750(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|dip:DIP-61292N|refseq:NP_001012453.1|refseq:NP_001012454.1|refseq:NP_536719.2|refseq:XP_006537671.1|refseq:XP_011248221.1|refseq:XP_011248222.1|refseq:XP_011248223.1|refseq:XP_011248224.1|refseq:XP_011248225.1|refseq:XP_011248226.1|entrezgene/locuslink:140577(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Sj6jU41VI/QsFuwN58z/XXZetA10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:2mWEuhEe2I7DXjl6BG93rqtISpk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88621 uniprotkb:O35137 intact:EBI-7457430|intact:MINT-4998752|uniprotkb:Q9QZL5|uniprotkb:Q9R241|ensembl:ENSMUSP00000036591 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:foxh1_mouse(display_long)|uniprotkb:Foxh1(gene name)|psi-mi:Foxh1(display_short)|uniprotkb:Fast1(gene name synonym)|uniprotkb:Fast2(gene name synonym)|uniprotkb:Forkhead activin signal transducer 1(gene name synonym)|uniprotkb:Forkhead activin signal transducer 2(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668697|imex:IM-28774-3207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032015.1|refseq:XP_006520499.1|ensembl:ENSMUSG00000033837(gene)|ensembl:ENSMUST00000037824(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:O88621|reactome:R-MMU-1181150|reactome:R-MMU-1502540|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|entrezgene/locuslink:14106(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - function:"Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element)"|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/wralkUfGdtYTuVGaOKelphRTTc10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:yAZO5yXW2j56m1jjPVocnYSXC70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96DX5 uniprotkb:Q15369 intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|ensembl:ENSP00000369855|intact:EBI-2349899|uniprotkb:Q9BVF5 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668673|imex:IM-28774-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|ensembl:ENST00000380488(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000102048(gene)|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N|entrezgene/locuslink:140462(identity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N|entrezgene/locuslink:6921(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:lyAJerEYorX+H4NgVZnfdfxTgKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H765 uniprotkb:P09016 intact:EBI-3942509|uniprotkb:Q547Q2|uniprotkb:A8K1P2|ensembl:ENSP00000320893|ensembl:ENSP00000445622 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:asb8_human(display_long)|uniprotkb:ASB8(gene name)|psi-mi:ASB8(display_short)|uniprotkb:PP14212(orf name) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668665|imex:IM-28774-2363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177981(gene)|ensembl:ENST00000317697(transcript)|ensembl:ENST00000536549(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037332|mint:Q9H765|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_077000.1|refseq:NP_001306225.1|refseq:NP_001306226.1|refseq:NP_001306227.1|refseq:NP_001306228.1|refseq:NP_001306229.1|refseq:NP_001306230.1|entrezgene/locuslink:140461(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TLjOfkyUnX91j0Lh2kZvf2uBMGI9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:QjhD3i4rUPUCCLwuuz6JEUFxSmk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61545 uniprotkb:P79621 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668657|imex:IM-28774-1473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:QML9e5f2lGFkQx2QIpUZqHcQAz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61545 uniprotkb:P48754 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 intact:EBI-6876136|ensembl:ENSMUSP00000017290|uniprotkb:A2A4Q4|uniprotkb:Q60957|uniprotkb:Q60983 psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:brca1_mouse(display_long)|uniprotkb:Brca1(gene name)|psi-mi:Brca1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668649|imex:IM-28774-2763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|reactome:R-MMU-3108214|ensembl:ENSMUSG00000017146(gene)|ensembl:ENSMUST00000017290(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|refseq:NP_033894.3|dip:DIP-41981N|entrezgene/locuslink:12189(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rogid:n930/noKAvHtITiW9/qUMSxbiT410090 rigid:AQ7M5JDghcTE22eddXY8LWlnnPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z353 uniprotkb:Q05516 intact:EBI-1052734|uniprotkb:Q5JZB4|uniprotkb:Q96NK7|uniprotkb:A8K1Y5|uniprotkb:B7ZL18|ensembl:ENSP00000297977|ensembl:ENSP00000362272 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 psi-mi:hdx_human(display_long)|uniprotkb:HDX(gene name)|psi-mi:HDX(display_short)|uniprotkb:CXorf43(gene name synonym) psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668641|imex:IM-28774-1915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170949.1|refseq:NP_001170950.1|refseq:NP_653258.2|refseq:XP_011529165.1|refseq:XP_011529166.1|refseq:XP_006724682.1|ensembl:ENSG00000165259(gene)|ensembl:ENST00000297977(transcript)|ensembl:ENST00000373177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|rcsb pdb:2DA4|refseq:XP_016884763.1|entrezgene/locuslink:139324(identity) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N|entrezgene/locuslink:7704(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nhMJWu8xnF2FDhtzcHcpjLftNjE9606 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 rigid:XBAhdQtRNnVnwtKWHaARDAJ1NN0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7Z353 uniprotkb:Q9UMX1 intact:EBI-1052734|uniprotkb:Q5JZB4|uniprotkb:Q96NK7|uniprotkb:A8K1Y5|uniprotkb:B7ZL18|ensembl:ENSP00000297977|ensembl:ENSP00000362272 intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918 psi-mi:hdx_human(display_long)|uniprotkb:HDX(gene name)|psi-mi:HDX(display_short)|uniprotkb:CXorf43(gene name synonym) psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668633|imex:IM-28774-3205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170949.1|refseq:NP_001170950.1|refseq:NP_653258.2|refseq:XP_011529165.1|refseq:XP_011529166.1|refseq:XP_006724682.1|ensembl:ENSG00000165259(gene)|ensembl:ENST00000297977(transcript)|ensembl:ENST00000373177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|rcsb pdb:2DA4|refseq:XP_016884763.1|entrezgene/locuslink:139324(identity) refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|entrezgene/locuslink:51684(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nhMJWu8xnF2FDhtzcHcpjLftNjE9606 rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606 rigid:tBiFa3p70Sap/R/UfTN3IAtIExE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15336 uniprotkb:P18847 intact:EBI-1170906|uniprotkb:Q13000|uniprotkb:Q4ZFU9|uniprotkb:Q53RY2|uniprotkb:A1L3Z2|uniprotkb:D3DPE9|uniprotkb:Q8TAR1|uniprotkb:A4D7U4|uniprotkb:G8JLM5|uniprotkb:Q3B7B7|uniprotkb:A4D7U5|uniprotkb:A4D7V1|uniprotkb:Q96JT8|intact:EBI-28988937|ensembl:ENSP00000264110|ensembl:ENSP00000376327 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:atf2_human(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:CREB2(gene name synonym)|uniprotkb:CREBP1(gene name synonym)|uniprotkb:Activating transcription factor 2(gene name synonym)|uniprotkb:cAMP response element-binding protein CRE-BP1(gene name synonym)|uniprotkb:HB16(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668625|imex:IM-28774-1009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243019.1|refseq:NP_001243020.1|refseq:NP_001871.2|refseq:NP_001243023.1|ensembl:ENST00000345739|ensembl:ENSP00000340576|ensembl:ENSP00000376327|ensembl:ENST00000409499|ensembl:ENSP00000386282|ensembl:ENST00000409635|ensembl:ENSP00000387093|ensembl:ENST00000409833|ensembl:ENSP00000386526|ensembl:ENST00000426833|ensembl:ENSP00000407911|ensembl:ENSP00000264110|refseq:NP_001243021.1|refseq:NP_001243022.1|ensembl:ENSG00000115966(gene)|ensembl:ENST00000264110(transcript)|ensembl:ENST00000392544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032915"(positive regulation of transforming growth factor beta2 production)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902562"(H4 histone acetyltransferase complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR029836|interpro:IPR036236|mint:P15336|rcsb pdb:1BHI|rcsb pdb:1T2K|rcsb pdb:4H36|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|rcsb pdb:6ZQS|rcsb pdb:6ZR5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-450341|reactome:R-HSA-6796648|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9633012|reactome:R-HSA-9707616|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044013"(H2B histone acetyltransferase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097186"(amelogenesis)|dip:DIP-632N|entrezgene/locuslink:1386(identity) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N|entrezgene/locuslink:467(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9krWq+A9Y3xvkInqyJnJs1g9tfc9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rigid:6x+K2WQOFCM6+vXP+nBlETjKu1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70396 uniprotkb:P43241 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 intact:EBI-26668158|ensembl:ENSMUSP00000031650 psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:cdx2_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 2(gene name synonym)|uniprotkb:Cdx2(gene name)|psi-mi:Cdx2(display_short)|uniprotkb:Cdx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668617|imex:IM-28774-2361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) ensembl:ENSMUSG00000029646(gene)|ensembl:ENSMUST00000031650(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0060711"(labyrinthine layer development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_031699.2|entrezgene/locuslink:12591(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rogid:1XpCK7ehS+3cgrG8vncU1t2kkpQ10090 rigid:cXSJR+aBfcEnomtRMydF1unFZQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70396 uniprotkb:O35137 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668609|imex:IM-28774-1471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:tmWquS2CTu+4qiNJZr9ki4MW93A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70396 uniprotkb:O35137 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668601|imex:IM-28774-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:tmWquS2CTu+4qiNJZr9ki4MW93A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40764 uniprotkb:Q64317 intact:EBI-26668537|ensembl:ENSMUSP00000024159 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:dlx2_mouse(display_long)|uniprotkb:Homeobox protein TES-1(gene name synonym)|uniprotkb:Dlx2(gene name)|psi-mi:Dlx2(display_short)|uniprotkb:Tes-1(gene name synonym)|uniprotkb:Tes1(gene name synonym) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668593|imex:IM-28774-1913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|ensembl:ENSMUSG00000023391(gene)|ensembl:ENSMUST00000024159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|refseq:NP_034184.1|entrezgene/locuslink:13392(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UiMEIffYTfo4n1rQRSlJ+B4MG8c10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:J9PVz4MmvtTJ2trlpKgWhgtM74Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40764 uniprotkb:O35137 intact:EBI-26668537|ensembl:ENSMUSP00000024159 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:dlx2_mouse(display_long)|uniprotkb:Homeobox protein TES-1(gene name synonym)|uniprotkb:Dlx2(gene name)|psi-mi:Dlx2(display_short)|uniprotkb:Tes-1(gene name synonym)|uniprotkb:Tes1(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668585|imex:IM-28774-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|ensembl:ENSMUSG00000023391(gene)|ensembl:ENSMUST00000024159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|refseq:NP_034184.1|entrezgene/locuslink:13392(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UiMEIffYTfo4n1rQRSlJ+B4MG8c10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:nrkL4HPJ8VzYFkguyVPkFKsThJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64317 uniprotkb:Q07424 intact:EBI-26668417|ensembl:ENSMUSP00000042413 intact:EBI-26668214|ensembl:ENSMUSP00000033689 psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:cdx4_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)|uniprotkb:Cdx4(gene name)|psi-mi:Cdx4(display_short)|uniprotkb:Cdx-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668529|imex:IM-28774-1469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) ensembl:ENSMUSG00000031326(gene)|ensembl:ENSMUST00000033689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_031700.1|entrezgene/locuslink:12592(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rogid:ZygM/NoxCumicSJlDzHtwO/L33410090 rigid:zCzviBJK9EInpcjCliTOJMrMLtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64317 uniprotkb:P18111 intact:EBI-26668417|ensembl:ENSMUSP00000042413 intact:EBI-21005290|ensembl:ENSMUSP00000025521|uniprotkb:Q8VCF7 psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:cdx1_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 1(gene name synonym)|uniprotkb:Cdx1(gene name)|psi-mi:Cdx1(display_short)|uniprotkb:Cdx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668521|imex:IM-28774-1467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060349"(bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000024619(gene)|ensembl:ENSMUST00000025521(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|refseq:NP_034010.3|entrezgene/locuslink:12590(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rogid:Rzc2qIxNozTifZX/rvuUx8uc6lU10090 rigid:dudK+ekhKFHWMkupyDUXmueEnbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64317 uniprotkb:Q9ER42 intact:EBI-26668417|ensembl:ENSMUSP00000042413 intact:EBI-26668483|ensembl:ENSMUSP00000021813|uniprotkb:O09066|uniprotkb:P70159|uniprotkb:Q0VF04|uniprotkb:Q9ERV2 psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:barx1_mouse(display_long)|uniprotkb:Barx1(gene name)|psi-mi:Barx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668513|imex:IM-28774-1465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) ensembl:ENSMUSG00000021381(gene)|ensembl:ENSMUST00000021813(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009888"(tissue development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0055123"(digestive system development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048513"(animal organ development)|go:"GO:0048536"(spleen development)|refseq:NP_031552.2|entrezgene/locuslink:12022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rogid:V+GjyYmD/YOniBu1zoeQp/wF7dw10090 rigid:l66bpUaHgwhbpxztofJ/jTQuodc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64317 uniprotkb:O35137 intact:EBI-26668417|ensembl:ENSMUSP00000042413 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668475|imex:IM-28774-1463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:wKxpeniT7OMAqopXRJVKn7OuVE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64317 uniprotkb:O35137 intact:EBI-26668417|ensembl:ENSMUSP00000042413 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668467|imex:IM-28774-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:wKxpeniT7OMAqopXRJVKn7OuVE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:Q9UDV6 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668409|imex:IM-28774-1007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rigid:dYwdikMVVwL9ulf+UW1N4aYFpB8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:P98182 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-3913354|uniprotkb:O15361|uniprotkb:Q5XKM5|uniprotkb:D3DUB8|uniprotkb:D3DUB7|uniprotkb:Q7Z5V1|ensembl:ENSP00000395723|ensembl:ENSP00000405786 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:zn200_human(display_long)|uniprotkb:ZNF200(gene name)|psi-mi:ZNF200(display_short)|uniprotkb:ZNFMF(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668401|imex:IM-28774-1005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) refseq:XP_006721003.1|refseq:XP_006721004.1|refseq:NP_001138918.1|refseq:NP_001138919.1|refseq:NP_001138920.1|refseq:NP_003445.2|refseq:NP_932353.1|refseq:NP_932354.1|refseq:XP_005255613.1|refseq:XP_016879136.1|ensembl:ENST00000414144(transcript)|ensembl:ENST00000431561(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000010539(gene)|entrezgene/locuslink:7752(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:TDSqaG6E8fZaY1t/cyPmEMF8Fzg9606 rigid:txKTFIZTAhZlJGVttdHBFYtxyAc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:Q9NTW7 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668393|imex:IM-28774-2359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606 rigid:mBaHasdXpaSB4NJxaEtVDihzBrA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:P51610 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668385|imex:IM-28774-1003 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|entrezgene/locuslink:3054(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:v+CggvQRYSO/s1N0rcz4KR3Q9tY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:P51610 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668377|imex:IM-28774-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|entrezgene/locuslink:3054(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:v+CggvQRYSO/s1N0rcz4KR3Q9tY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:P62508 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668369|imex:IM-28774-1001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1|entrezgene/locuslink:2104(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606 rigid:XNw6QGDWRn3w7Zh63zqxevQdmZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86YN6 uniprotkb:Q8N8E2 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 intact:EBI-10279993|uniprotkb:Q86UZ3|uniprotkb:B7WP71|uniprotkb:Q3ZCU1|uniprotkb:A8K3S5|uniprotkb:Q8NDL8|uniprotkb:Q68CJ1|uniprotkb:Q96ML3|intact:EBI-28970619|ensembl:ENSP00000318373 psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:zn513_human(display_long)|uniprotkb:ZNF513(gene name)|psi-mi:ZNF513(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668361|imex:IM-28774-1461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) ensembl:ENSP00000318373|ensembl:ENST00000407879|ensembl:ENSP00000384874|refseq:NP_001188388.1|refseq:NP_653232.3|refseq:XP_005264199.1|refseq:XP_005264200.1|ensembl:ENSG00000163795(gene)|ensembl:ENST00000323703(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:130557(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rogid:MMEJhQrXKOTRNB7d66GD7NyfIwo9606 rigid:YFUW88gCOVbPIwQfS/SgzndMT+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35639 uniprotkb:P53566 intact:EBI-10636142|uniprotkb:Q91YW9|ensembl:ENSMUSP00000026475 intact:EBI-2644207|uniprotkb:Q91XB6|ensembl:ENSMUSP00000096129 psi-mi:ddit3_mouse(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym) psi-mi:cebpa_mouse(display_long)|uniprotkb:Cebpa(gene name)|psi-mi:Cebpa(display_short)|uniprotkb:Cebp(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668353|imex:IM-28774-2357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277112.1|refseq:NP_031863.3|refseq:XP_006513260.1|ensembl:ENSMUSG00000025408(gene)|ensembl:ENSMUST00000026475(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|dip:DIP-60705N|entrezgene/locuslink:13198(identity) refseq:NP_031704.2|refseq:NP_001274443.1|refseq:NP_001274444.1|refseq:NP_001274450.1|ensembl:ENSMUSG00000034957(gene)|ensembl:ENSMUST00000042985(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P53566|reactome:R-MMU-9616222|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|dip:DIP-44054N|entrezgene/locuslink:12606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ltrRdLwc8dwkKYkmxIAmq4iuFfA10090 rogid:pGJ6XTpLySPEYPc9uYgeawD6WTk10090 rigid:zFyAbQdfTfTAk9+WDSBgiGlr2b4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35582 uniprotkb:Q64317 intact:EBI-11515814|uniprotkb:Q4VA63|uniprotkb:Q61108|ensembl:ENSMUSP00000041118 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:foxa1_mouse(display_long)|uniprotkb:Forkhead box protein A1(gene name synonym)|uniprotkb:Foxa1(gene name)|psi-mi:Foxa1(display_short)|uniprotkb:Hnf3a(gene name synonym)|uniprotkb:Tcf-3a(gene name synonym)|uniprotkb:Tcf3a(gene name synonym) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668798|imex:IM-28774-1011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032285.2|refseq:XP_006515542.1|refseq:XP_006515544.1|refseq:XP_006515546.1|ensembl:ENSMUSG00000035451(gene)|ensembl:ENSMUST00000044380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032355"(response to estradiol)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060738"(epithelial-mesenchymal signaling involved in prostate gland development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060741"(prostate gland stromal morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:0061144"(alveolar secondary septum development)|go:"GO:0061448"(connective tissue development)|go:"GO:1902691"(respiratory basal cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR018533|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-MMU-9018519|refseq:XP_017170451.1|entrezgene/locuslink:15375(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GScFT/iLixrzWVUXlf8ADqetLWE10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:qY8LwBc7zJ4WZbkcb+ugMMiozLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35582 uniprotkb:O35137 intact:EBI-11515814|uniprotkb:Q4VA63|uniprotkb:Q61108|ensembl:ENSMUSP00000041118 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:foxa1_mouse(display_long)|uniprotkb:Forkhead box protein A1(gene name synonym)|uniprotkb:Foxa1(gene name)|psi-mi:Foxa1(display_short)|uniprotkb:Hnf3a(gene name synonym)|uniprotkb:Tcf-3a(gene name synonym)|uniprotkb:Tcf3a(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668790|imex:IM-28774-1917 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032285.2|refseq:XP_006515542.1|refseq:XP_006515544.1|refseq:XP_006515546.1|ensembl:ENSMUSG00000035451(gene)|ensembl:ENSMUST00000044380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0032355"(response to estradiol)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060738"(epithelial-mesenchymal signaling involved in prostate gland development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060741"(prostate gland stromal morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:0061144"(alveolar secondary septum development)|go:"GO:0061448"(connective tissue development)|go:"GO:1902691"(respiratory basal cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR018533|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-MMU-9018519|refseq:XP_017170451.1|entrezgene/locuslink:15375(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GScFT/iLixrzWVUXlf8ADqetLWE10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:WfeqGi6K91AmceZmUOl4WD1nP2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96N38 uniprotkb:Q8N653 intact:EBI-26643252|uniprotkb:Q49AI1|uniprotkb:Q86W65|uniprotkb:Q8ND40 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zn714_human(display_long)|uniprotkb:ZNF714(gene name)|psi-mi:ZNF714(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668782|imex:IM-28774-2369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_872321.2|entrezgene/locuslink:148206(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xYcDBvo2LQUlqlYkHyMuf/f5r4o9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:OG7sa94yHkdpVQYx8efOSoN+NZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96N38 uniprotkb:P61457 intact:EBI-26643252|uniprotkb:Q49AI1|uniprotkb:Q86W65|uniprotkb:Q8ND40 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zn714_human(display_long)|uniprotkb:ZNF714(gene name)|psi-mi:ZNF714(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668774|imex:IM-28774-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_872321.2|entrezgene/locuslink:148206(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xYcDBvo2LQUlqlYkHyMuf/f5r4o9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:T9zVp+dg5sE4R3aBuCmlDeYRGb4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96LX8 uniprotkb:Q96LX8 intact:EBI-9091553|ensembl:ENSP00000301744 intact:EBI-9091553|ensembl:ENSP00000301744 psi-mi:zn597_human(display_long)|uniprotkb:ZNF597(gene name)|psi-mi:ZNF597(display_short) psi-mi:zn597_human(display_long)|uniprotkb:ZNF597(gene name)|psi-mi:ZNF597(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668758|imex:IM-28774-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689670.1|ensembl:ENSG00000167981(gene)|ensembl:ENST00000301744(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146434(identity) refseq:NP_689670.1|ensembl:ENSG00000167981(gene)|ensembl:ENST00000301744(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:146434(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJU9gbrQDuar5o6bWN1LwUMcUAc9606 rogid:wJU9gbrQDuar5o6bWN1LwUMcUAc9606 rigid:2uoxprg2M7EzMVkdLwEbqxbhQEY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61169 uniprotkb:Q04742 intact:EBI-8065049|uniprotkb:Q9QZK3|intact:MINT-1782188|uniprotkb:Q3UQJ2|uniprotkb:P97729|ensembl:ENSMUSP00000041774 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:gata6_mouse(display_long)|uniprotkb:Gata6(gene name)|psi-mi:Gata6(display_short)|uniprotkb:GATA-binding factor 6(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668750|imex:IM-28774-2367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034388.2|go:"GO:0032526"(response to retinoic acid)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007493"(endodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032912"(negative regulation of transforming growth factor beta2 production)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031016"(pancreas development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048645"(animal organ formation)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070848"(response to growth factor)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098773"(skin epidermis development)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1901390"(positive regulation of transforming growth factor beta activation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1904003"(negative regulation of sebum secreting cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028437|interpro:IPR039355|reactome:R-MMU-5683826|reactome:R-MMU-983231|ensembl:ENSMUSG00000005836(gene)|ensembl:ENSMUST00000047762(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001949"(sebaceous gland cell differentiation)|go:"GO:0002759"(regulation of antimicrobial humoral response)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|entrezgene/locuslink:14465(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - comment:mint|function:Transcriptional activator. Involved in gene regulation specifically in the gastric epithelium - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+/EaZWnNKhcYt9x7ugHoBDbKg3Q10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:OX/c+NJoLVmOoMM4oEeKX5aJfys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXK4 uniprotkb:Q8N653 intact:EBI-7911975|intact:MINT-1500389|uniprotkb:Q52LK4|uniprotkb:J3KP57|uniprotkb:Q2M3D5|uniprotkb:Q8N8F5|uniprotkb:Q6ISF9 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:asb12_human(display_long)|uniprotkb:ASB12(gene name)|psi-mi:ASB12(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668705|imex:IM-28774-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020683|refseq:NP_569059.3|reactome:R-HSA-983168|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-8951664|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR036770|entrezgene/locuslink:142689(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - function:"Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VVzSyw5LFKkGA9NsTtkbgf+7+jQ9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:++imWRgh4bkde8we40sHR5WccNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96DX5 uniprotkb:Q15369 intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|ensembl:ENSP00000369855|intact:EBI-2349899|uniprotkb:Q9BVF5 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668681|imex:IM-28774-2765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|ensembl:ENST00000380488(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000102048(gene)|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N|entrezgene/locuslink:140462(identity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N|entrezgene/locuslink:6921(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:lyAJerEYorX+H4NgVZnfdfxTgKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08624 uniprotkb:O35137 intact:EBI-26668976|ensembl:ENSMUSP00000097740 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669011|imex:IM-28774-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:tu2sRlvPmupX+cU3jlfnEM31MQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K5B8 uniprotkb:P48754 intact:EBI-26668950|ensembl:ENSMUSP00000051003 intact:EBI-6876136|ensembl:ENSMUSP00000017290|uniprotkb:A2A4Q4|uniprotkb:Q60957|uniprotkb:Q60983 psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:brca1_mouse(display_long)|uniprotkb:Brca1(gene name)|psi-mi:Brca1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668968|imex:IM-28774-2767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|reactome:R-MMU-3108214|ensembl:ENSMUSG00000017146(gene)|ensembl:ENSMUST00000017290(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|refseq:NP_033894.3|dip:DIP-41981N|entrezgene/locuslink:12189(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rogid:n930/noKAvHtITiW9/qUMSxbiT410090 rigid:iWJvmkvSRF3KrOpleMLrWzLzj6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06537 uniprotkb:P09632 intact:EBI-492753|uniprotkb:Q61628|uniprotkb:Q61629|ensembl:ENSMUSP00000025300|ensembl:ENSMUSP00000095199|ensembl:ENSMUSP00000111229|ensembl:ENSMUSP00000111233|intact:EBI-26668912|uniprotkb:E9PUR6|uniprotkb:E0ZPU5|uniprotkb:Q06VW2|uniprotkb:Q3U126|uniprotkb:Q3U2M7|uniprotkb:E9PYV1 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:gcr_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym)|uniprotkb:Grl1(gene name synonym) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668942|imex:IM-28774-1013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024431(gene)|ensembl:ENSMUST00000025300(transcript)|ensembl:ENSMUST00000097592(transcript)|ensembl:ENSMUST00000115567(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|ensembl:ENSMUST00000115571(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|reactome:R-MMU-3371497|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048096"|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P06537|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|refseq:NP_032199.3|refseq:XP_006525721.1|refseq:XP_006525722.1|refseq:XP_006525723.1|refseq:XP_006525724.1|refseq:XP_006525725.1|refseq:XP_006525726.1|refseq:XP_006525727.1|refseq:XP_006525728.1|refseq:XP_006525729.1|refseq:XP_017173324.1|refseq:XP_017173325.1|refseq:XP_017173326.1|refseq:XP_017173327.1|dip:DIP-11N|entrezgene/locuslink:14815(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/11/30 rogid:BGeJbz2zNEPZBn4cdswdbgRBif410090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:gL6ntIjO4/Mdu4X3rIuHYjdab6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09632 uniprotkb:Q9Z2S7 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 intact:EBI-15771128|ensembl:ENSMUSP00000062589|uniprotkb:B1AVF3|uniprotkb:C6EX03|uniprotkb:Q3UNI6|uniprotkb:Q8K160|uniprotkb:Q9EQN0|uniprotkb:Q9EQN1|uniprotkb:Q9EQN2 psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:t22d3_mouse(display_long)|uniprotkb:Tsc22d3(gene name)|psi-mi:Tsc22d3(display_short)|uniprotkb:Dsip1(gene name synonym)|uniprotkb:Dsipi(gene name synonym)|uniprotkb:Gilz(gene name synonym)|uniprotkb:Glucocorticoid-induced leucine zipper protein(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668904|imex:IM-28774-2373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) ensembl:ENSMUSG00000031431(gene)|ensembl:ENSMUST00000055738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|interpro:IPR000580(TSC-22 / Dip / Bun)|reactome:R-MMU-2672351|refseq:NP_001070832.1|refseq:NP_034416.3|refseq:XP_006528562.1|refseq:XP_006528563.1|refseq:XP_006528564.1|refseq:XP_006528566.1|refseq:XP_006528567.1|refseq:XP_006528568.1|dip:DIP-48844N|entrezgene/locuslink:14605(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rogid:dL2mVYP+cp0QGH7QZuxZ5vWhWJI10090 rigid:g75xJhSsi1pZS6IdffODa1y+4lY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09632 uniprotkb:P97480 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 intact:EBI-349175|uniprotkb:P97768|ensembl:ENSMUSP00000078157|uniprotkb:G5E8I5 psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:eya3_mouse(display_long)|uniprotkb:Eya3(gene name)|psi-mi:Eya3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668896|imex:IM-28774-2371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) refseq:NP_034296.2|ensembl:ENSMUST00000079157(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR028479|interpro:IPR038102|interpro:IPR042577|reactome:R-MMU-5693565|ensembl:ENSMUSG00000028886(gene)|entrezgene/locuslink:14050(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rogid:0yaKFTJm3uCQYXt/sgj+aSmZOVI10090 rigid:dzaYgT1XKfnVQTFjIFEKpgy6z34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70321 uniprotkb:P70396 intact:EBI-925221|uniprotkb:Q80Y12|ensembl:ENSMUSP00000056315 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 psi-mi:hxb13_mouse(display_long)|uniprotkb:Hoxb13(gene name)|psi-mi:Hoxb13(display_short) psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668888|imex:IM-28774-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032293.1|ensembl:ENSMUSG00000049604(gene)|ensembl:ENSMUST00000062709(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:15408(identity) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yjyTaVd+DMfgTpGB9PF4iYLjXzU10090 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rigid:2Ww8896RrDVjVrtMvRs+24RS10M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31310 uniprotkb:O35137 intact:EBI-446033|uniprotkb:Q80Y22|ensembl:ENSMUSP00000120276 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxa10_mouse(display_long)|uniprotkb:Hoxa10(gene name)|psi-mi:Hoxa10(display_short)|uniprotkb:Hox-1.8(gene name synonym)|uniprotkb:Hoxa-10(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668806|imex:IM-28774-1475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116422.1|refseq:NP_032289.2|ensembl:ENSMUSG00000000938(gene)|ensembl:ENSMUST00000125581(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0010468"(regulation of gene expression)|entrezgene/locuslink:15395(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vWwVapO3YyVd8TG6MbGvBHZHOMo10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:WW9OZHVAkaAM3pXb0Y/ZNTAZBRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70321 uniprotkb:O35137 intact:EBI-925221|uniprotkb:Q80Y12|ensembl:ENSMUSP00000056315 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxb13_mouse(display_long)|uniprotkb:Hoxb13(gene name)|psi-mi:Hoxb13(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668872|imex:IM-28774-1481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032293.1|ensembl:ENSMUSG00000049604(gene)|ensembl:ENSMUST00000062709(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:15408(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yjyTaVd+DMfgTpGB9PF4iYLjXzU10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:RCNXjD32IDfFAmF0eg8tPP6dBYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09092 uniprotkb:Q9Z2S7 intact:EBI-26668838|ensembl:ENSMUSP00000058755|uniprotkb:Q9JI98 intact:EBI-15771128|ensembl:ENSMUSP00000062589|uniprotkb:B1AVF3|uniprotkb:C6EX03|uniprotkb:Q3UNI6|uniprotkb:Q8K160|uniprotkb:Q9EQN0|uniprotkb:Q9EQN1|uniprotkb:Q9EQN2 psi-mi:hxa6_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.2(gene name synonym)|uniprotkb:Homeobox protein M5-4(gene name synonym)|uniprotkb:Hoxa6(gene name)|psi-mi:Hoxa6(display_short)|uniprotkb:Hox-1.2(gene name synonym)|uniprotkb:Hoxa-6(gene name synonym) psi-mi:t22d3_mouse(display_long)|uniprotkb:Tsc22d3(gene name)|psi-mi:Tsc22d3(display_short)|uniprotkb:Dsip1(gene name synonym)|uniprotkb:Dsipi(gene name synonym)|uniprotkb:Gilz(gene name synonym)|uniprotkb:Glucocorticoid-induced leucine zipper protein(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668864|imex:IM-28774-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043219(gene)|ensembl:ENSMUST00000062829(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_034584.1|entrezgene/locuslink:15403(identity) ensembl:ENSMUSG00000031431(gene)|ensembl:ENSMUST00000055738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|interpro:IPR000580(TSC-22 / Dip / Bun)|reactome:R-MMU-2672351|refseq:NP_001070832.1|refseq:NP_034416.3|refseq:XP_006528562.1|refseq:XP_006528563.1|refseq:XP_006528564.1|refseq:XP_006528566.1|refseq:XP_006528567.1|refseq:XP_006528568.1|dip:DIP-48844N|entrezgene/locuslink:14605(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:h4344WEVFSGp7m6UWPSAQn7hIVU10090 rogid:dL2mVYP+cp0QGH7QZuxZ5vWhWJI10090 rigid:/UsPwna9vebcgN0ci7eiY/Cfrn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31245 uniprotkb:P79621 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668830|imex:IM-28774-1479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:faUexDm/4i4ELNhjuFAc0v+300I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31245 uniprotkb:P48754 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 intact:EBI-6876136|ensembl:ENSMUSP00000017290|uniprotkb:A2A4Q4|uniprotkb:Q60957|uniprotkb:Q60983 psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:brca1_mouse(display_long)|uniprotkb:Brca1(gene name)|psi-mi:Brca1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668822|imex:IM-28774-1477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|reactome:R-MMU-3108214|ensembl:ENSMUSG00000017146(gene)|ensembl:ENSMUST00000017290(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|refseq:NP_033894.3|dip:DIP-41981N|entrezgene/locuslink:12189(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rogid:n930/noKAvHtITiW9/qUMSxbiT410090 rigid:O9a47OW0sIIk/su0JrJd/9WvpH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31311 uniprotkb:O35137 intact:EBI-445941|uniprotkb:Q3V026|ensembl:ENSMUSP00000040920 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxa11_mouse(display_long)|uniprotkb:Hoxa11(gene name)|psi-mi:Hoxa11(display_short)|uniprotkb:Hox-1.9(gene name synonym)|uniprotkb:Hoxa-11(gene name synonym)|uniprotkb:Homeobox protein Hox-1.9(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668814|imex:IM-28774-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034580.1|ensembl:ENSMUSG00000038210(gene)|ensembl:ENSMUST00000048026(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010720"(positive regulation of cell development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048589"(developmental growth)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060065"(uterus development)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:15396(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xmuaYwHq6mzn6Qbx/zJIcMkoNsk10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:915vWW1mjTX9Kp/1b50wujhGUFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70321 uniprotkb:Q64317 intact:EBI-925221|uniprotkb:Q80Y12|ensembl:ENSMUSP00000056315 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:hxb13_mouse(display_long)|uniprotkb:Hoxb13(gene name)|psi-mi:Hoxb13(display_short) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668880|imex:IM-28774-1483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032293.1|ensembl:ENSMUSG00000049604(gene)|ensembl:ENSMUST00000062709(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:15408(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yjyTaVd+DMfgTpGB9PF4iYLjXzU10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:5wuWAvPoXr2YVK1fubFPM6s9eto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41133 uniprotkb:Q04742 intact:EBI-309448|ensembl:ENSMUSP00000008016 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:id3_mouse(display_long)|uniprotkb:Id3(gene name)|psi-mi:Id3(display_short)|uniprotkb:Hlh462(gene name synonym)|uniprotkb:Id-3(gene name synonym)|uniprotkb:Idb3(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 462(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669186|imex:IM-28774-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032347.1|ensembl:ENSMUSG00000007872(gene)|ensembl:ENSMUST00000008016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15903(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wRsCFFWeh4NnuA3HwTmiVahLDtI10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:nIF22XGlGq56EHaSt8s0GspAZyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41133 uniprotkb:Q61909 intact:EBI-309448|ensembl:ENSMUSP00000008016 intact:EBI-309458|ensembl:ENSMUSP00000095856 psi-mi:id3_mouse(display_long)|uniprotkb:Id3(gene name)|psi-mi:Id3(display_short)|uniprotkb:Hlh462(gene name synonym)|uniprotkb:Id-3(gene name synonym)|uniprotkb:Idb3(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 462(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669178|imex:IM-28774-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032347.1|ensembl:ENSMUSG00000007872(gene)|ensembl:ENSMUST00000008016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15903(identity) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wRsCFFWeh4NnuA3HwTmiVahLDtI10090 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rigid:WRoF3I9krt48fgaq6xERPFNd+YI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6GTZ3 uniprotkb:Q61909 intact:EBI-26669132 intact:EBI-309458|ensembl:ENSMUSP00000095856 psi-mi:q6gtz3_mouse(display_long)|uniprotkb:Id1(gene name)|psi-mi:Id1(display_short)|uniprotkb:Idb1(gene name synonym) psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669170|imex:IM-28774-2771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_034625.1|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15901(identity) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IRUXStmLzIzQ5jb8Aw8r0MhfKPc10090 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rigid:JnwNMGfEZaF0l/6MqyCZY+SIXX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHV9 uniprotkb:Q99743 intact:EBI-3923409|ensembl:ENSP00000217999|uniprotkb:Q3SYE0|uniprotkb:O95030 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:rhxf1_human(display_long)|uniprotkb:RHOXF1(gene name)|psi-mi:RHOXF1(display_short)|uniprotkb:Ovary-, testis- and epididymis-expressed gene protein(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-1(gene name synonym)|uniprotkb:OTEX(gene name synonym)|uniprotkb:PEPP1(gene name synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669124|imex:IM-28774-3211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101883(gene)|ensembl:ENST00000217999(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007276"(gamete generation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0048484"(enteric nervous system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_644811.1|entrezgene/locuslink:158800(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9yia/i9hNSpXlNk0PKCqTq5SQJ89606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:OD5h8nH14PadUP+3UNTGVf3itGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61645 uniprotkb:Q61645 intact:EBI-21991144|uniprotkb:Q80Y47|ensembl:ENSMUSP00000022691|ensembl:ENSMUSP00000124816 intact:EBI-21991144|uniprotkb:Q80Y47|ensembl:ENSMUSP00000022691|ensembl:ENSMUSP00000124816 psi-mi:hair_mouse(display_long)|uniprotkb:Hr(gene name)|psi-mi:Hr(display_short)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym) psi-mi:hair_mouse(display_long)|uniprotkb:Hr(gene name)|psi-mi:Hr(display_short)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669108|imex:IM-28774-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068677.2|refseq:XP_011243268.1|ensembl:ENSMUSG00000022096(gene)|ensembl:ENSMUST00000022691(transcript)|ensembl:ENSMUST00000161069(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|entrezgene/locuslink:15460(identity) refseq:NP_068677.2|refseq:XP_011243268.1|ensembl:ENSMUSG00000022096(gene)|ensembl:ENSMUST00000022691(transcript)|ensembl:ENSMUST00000161069(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|entrezgene/locuslink:15460(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9/Ts7qpEFX5F+Sb7TT+I9aFeaPs10090 rogid:9/Ts7qpEFX5F+Sb7TT+I9aFeaPs10090 rigid:zIbxSB82sLzgnM32F+FD8zvK+qk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08624 uniprotkb:O35137 intact:EBI-26668976|ensembl:ENSMUSP00000097740 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669019|imex:IM-28774-1485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:tu2sRlvPmupX+cU3jlfnEM31MQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70217 uniprotkb:O35137 intact:EBI-925264|uniprotkb:Q2VPB0|uniprotkb:A2ASM5|uniprotkb:Q2VPB1|uniprotkb:Q64177|ensembl:ENSMUSP00000001872 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxd13_mouse(display_long)|uniprotkb:Hoxd13(gene name)|psi-mi:Hoxd13(display_short)|uniprotkb:Hox-4.8(gene name synonym)|uniprotkb:Homeobox protein Hox-4.8(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669092|imex:IM-28774-2375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032301.2|ensembl:ENSMUSG00000001819(gene)|ensembl:ENSMUST00000001872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030539"(male genitalia development)|go:"GO:0033574"(response to testosterone)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060602"(branch elongation of an epithelium)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|mint:P70217|entrezgene/locuslink:15433(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FWeR98eKeTKa8R6EG03n7Gelgi410090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:90aeorb4tl0N5PBsaLN+WCMQwnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70217 uniprotkb:O35137 intact:EBI-925264|uniprotkb:Q2VPB0|uniprotkb:A2ASM5|uniprotkb:Q2VPB1|uniprotkb:Q64177|ensembl:ENSMUSP00000001872 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxd13_mouse(display_long)|uniprotkb:Hoxd13(gene name)|psi-mi:Hoxd13(display_short)|uniprotkb:Hox-4.8(gene name synonym)|uniprotkb:Homeobox protein Hox-4.8(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669084|imex:IM-28774-1015 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032301.2|ensembl:ENSMUSG00000001819(gene)|ensembl:ENSMUST00000001872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030539"(male genitalia development)|go:"GO:0033574"(response to testosterone)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060602"(branch elongation of an epithelium)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|mint:P70217|entrezgene/locuslink:15433(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FWeR98eKeTKa8R6EG03n7Gelgi410090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:90aeorb4tl0N5PBsaLN+WCMQwnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23812 uniprotkb:P61202 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 intact:EBI-26669035|ensembl:ENSMUSP00000028635|uniprotkb:O88950|uniprotkb:Q15647|uniprotkb:Q3V1W6|uniprotkb:Q8R5B0|uniprotkb:Q9CWU1|uniprotkb:Q9R249|uniprotkb:Q9UNQ5 psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:csn2_mouse(display_long)|uniprotkb:Alien homolog(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym)|uniprotkb:Cops2(gene name)|psi-mi:Cops2(display_short)|uniprotkb:Csn2(gene name synonym)|uniprotkb:Trip15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669076|imex:IM-28774-3209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) ensembl:ENSMUSG00000027206(gene)|ensembl:ENSMUST00000028635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|reactome:R-MMU-5696394|reactome:R-MMU-6781823|reactome:R-MMU-8856825|reactome:R-MMU-8951664|reactome:R-MMU-9013422|refseq:NP_001272441.1|refseq:NP_034069.2|entrezgene/locuslink:12848(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rogid:MrlEHktIBvvcQux7Z7kqYJYgbbs10090 rigid:+UWDEkP3sqnIEHsRmT407OYBzxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23812 uniprotkb:O35137 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669027|imex:IM-28774-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:m5CrWBFAuTtJNZ6vTmJP14GirMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61645 uniprotkb:P31311 intact:EBI-21991144|uniprotkb:Q80Y47|ensembl:ENSMUSP00000022691|ensembl:ENSMUSP00000124816 intact:EBI-445941|uniprotkb:Q3V026|ensembl:ENSMUSP00000040920 psi-mi:hair_mouse(display_long)|uniprotkb:Hr(gene name)|psi-mi:Hr(display_short)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym) psi-mi:hxa11_mouse(display_long)|uniprotkb:Hoxa11(gene name)|psi-mi:Hoxa11(display_short)|uniprotkb:Hox-1.9(gene name synonym)|uniprotkb:Hoxa-11(gene name synonym)|uniprotkb:Homeobox protein Hox-1.9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669100|imex:IM-28774-1919 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068677.2|refseq:XP_011243268.1|ensembl:ENSMUSG00000022096(gene)|ensembl:ENSMUST00000022691(transcript)|ensembl:ENSMUST00000161069(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|entrezgene/locuslink:15460(identity) refseq:NP_034580.1|ensembl:ENSMUSG00000038210(gene)|ensembl:ENSMUST00000048026(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010720"(positive regulation of cell development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048589"(developmental growth)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060065"(uterus development)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:15396(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9/Ts7qpEFX5F+Sb7TT+I9aFeaPs10090 rogid:xmuaYwHq6mzn6Qbx/zJIcMkoNsk10090 rigid:rLK/2gvA2IlPhb17E6Psln7M81g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41139 uniprotkb:Q61909 intact:EBI-1213725|ensembl:ENSMUSP00000021810 intact:EBI-309458|ensembl:ENSMUSP00000095856 psi-mi:id4_mouse(display_long)|uniprotkb:Id4(gene name)|psi-mi:Id4(display_short)|uniprotkb:Id-4(gene name synonym)|uniprotkb:Idb4(gene name synonym)|uniprotkb:Inhibitor of DNA binding 4(gene name synonym)|uniprotkb:Inhibitor of differentiation 4(gene name synonym) psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669194|imex:IM-28774-2377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112443.1|ensembl:ENSMUSG00000021379(gene)|ensembl:ENSMUST00000021810(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021766"(hippocampus development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0060512"(prostate gland morphogenesis)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060741"(prostate gland stromal morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061682"(seminal vesicle morphogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15904(identity) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Op/IglgKKLeE6VDL7BHOAQrQltU10090 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rigid:jTK5t3+KPhGQXIujtxFaxXyd9l4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TAU0 uniprotkb:Q9UNN4 intact:EBI-1640929|uniprotkb:Q9NYS6|uniprotkb:B4DUZ4|ensembl:ENSP00000342828 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 psi-mi:nkx23_human(display_long)|uniprotkb:NKX2-3(gene name)|psi-mi:NKX2-3(display_short)|uniprotkb:NKX23(gene name synonym)|uniprotkb:NKX2C(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog C(gene name synonym) psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669202|imex:IM-28774-3213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_660328.2|ensembl:ENSG00000119919(gene)|ensembl:ENST00000344586(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048621"(post-embryonic digestive tract morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:159296(identity) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GfdcZ5et9FuSHHNuZzPzxMc4zbk9606 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rigid:k4MSptUUarw9+bGAQaPiC9KQhbY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0S2 uniprotkb:O55203 intact:EBI-26669558|ensembl:ENSMUSP00000000253 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669628|imex:IM-28774-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:9ZP5Srld+I/3hulzq4PmZR3mLuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0S2 uniprotkb:O55203 intact:EBI-26669558|ensembl:ENSMUSP00000000253 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669620|imex:IM-28774-1927 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:9ZP5Srld+I/3hulzq4PmZR3mLuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0S2 uniprotkb:P70662 intact:EBI-26669558|ensembl:ENSMUSP00000000253 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669612|imex:IM-28774-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:tBKRmHfbR3oJNlCvmGj/b4TMLtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0S2 uniprotkb:P70662 intact:EBI-26669558|ensembl:ENSMUSP00000000253 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669604|imex:IM-28774-1023 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:tBKRmHfbR3oJNlCvmGj/b4TMLtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63006 uniprotkb:O55203 intact:EBI-26669446|ensembl:ENSMUSP00000018842|uniprotkb:P36199 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx1_mouse(display_long)|uniprotkb:Homeobox protein Lim-1(gene name synonym)|uniprotkb:Lhx1(gene name)|psi-mi:Lhx1(display_short)|uniprotkb:Lim-1(gene name synonym)|uniprotkb:Lim1(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669550|imex:IM-28774-1487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018698(gene)|ensembl:ENSMUST00000018842(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001705"(ectoderm formation)|go:"GO:0001706"(endoderm formation)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007492"(endoderm development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0021510"(spinal cord development)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0021937"(cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0035847"(uterine epithelium development)|go:"GO:0035849"(nephric duct elongation)|go:"GO:0035852"(horizontal cell localization)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060065"(uterus development)|go:"GO:0060066"(oviduct development)|go:"GO:0060067"(cervix development)|go:"GO:0060068"(vagina development)|go:"GO:0060322"(head development)|go:"GO:0060429"(epithelium development)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0072049"(comma-shaped body morphogenesis)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072077"(renal vesicle morphogenesis)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072224"(metanephric glomerulus development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072283"(metanephric renal vesicle morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0097477"(lateral motor column neuron migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000744"(positive regulation of anterior head development)|go:"GO:2000768"(positive regulation of nephron tubule epithelial cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_032524.1|entrezgene/locuslink:16869(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:elVq8yNw5yQxURT6JAHs9GmVG2s10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:38gQb169y7Z8RJkfSEdNLkheJZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63006 uniprotkb:P70662 intact:EBI-26669446|ensembl:ENSMUSP00000018842|uniprotkb:P36199 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx1_mouse(display_long)|uniprotkb:Homeobox protein Lim-1(gene name synonym)|uniprotkb:Lhx1(gene name)|psi-mi:Lhx1(display_short)|uniprotkb:Lim-1(gene name synonym)|uniprotkb:Lim1(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669542|imex:IM-28774-1021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000018698(gene)|ensembl:ENSMUST00000018842(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001705"(ectoderm formation)|go:"GO:0001706"(endoderm formation)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007492"(endoderm development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0021510"(spinal cord development)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0021937"(cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0035847"(uterine epithelium development)|go:"GO:0035849"(nephric duct elongation)|go:"GO:0035852"(horizontal cell localization)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060065"(uterus development)|go:"GO:0060066"(oviduct development)|go:"GO:0060067"(cervix development)|go:"GO:0060068"(vagina development)|go:"GO:0060322"(head development)|go:"GO:0060429"(epithelium development)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0072049"(comma-shaped body morphogenesis)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072077"(renal vesicle morphogenesis)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072224"(metanephric glomerulus development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072283"(metanephric renal vesicle morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0097477"(lateral motor column neuron migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000744"(positive regulation of anterior head development)|go:"GO:2000768"(positive regulation of nephron tubule epithelial cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_032524.1|entrezgene/locuslink:16869(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:elVq8yNw5yQxURT6JAHs9GmVG2s10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:EYoSDKUZO6qTkSfYmBUu4aBMkpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03936 uniprotkb:P42226 intact:EBI-12176441|uniprotkb:A6NNF9|uniprotkb:Q8N492|uniprotkb:Q8NB35|ensembl:ENSP00000332595 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:znf92_human(display_long)|uniprotkb:ZNF92(gene name)|psi-mi:ZNF92(display_short)|uniprotkb:Zinc finger protein HTF12(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669438|imex:IM-28774-1925 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001274461.1|refseq:NP_001274462.1|refseq:NP_001274463.1|refseq:NP_009070.2|refseq:NP_689839.1|ensembl:ENSG00000146757(gene)|ensembl:ENST00000328747(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:168374(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:D8ynIx6f2dsJEtfiooPRrIII79I9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:L2ojpG3OWvZZ0JHc+oJqihL0eko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03936 uniprotkb:P16220 intact:EBI-12176441|uniprotkb:A6NNF9|uniprotkb:Q8N492|uniprotkb:Q8NB35|ensembl:ENSP00000332595 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:znf92_human(display_long)|uniprotkb:ZNF92(gene name)|psi-mi:ZNF92(display_short)|uniprotkb:Zinc finger protein HTF12(gene name synonym) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669430|imex:IM-28774-2383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001274461.1|refseq:NP_001274462.1|refseq:NP_001274463.1|refseq:NP_009070.2|refseq:NP_689839.1|ensembl:ENSG00000146757(gene)|ensembl:ENST00000328747(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:168374(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:D8ynIx6f2dsJEtfiooPRrIII79I9606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:1JPReCkSOalIK0fdkizKWoyGsKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61372 uniprotkb:O55203 intact:EBI-7988215|uniprotkb:P47894|uniprotkb:Q812D8|uniprotkb:P20663|intact:MINT-4594016|ensembl:ENSMUSP00000044879 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:isl1_mouse(display_long)|uniprotkb:Isl1(gene name)|psi-mi:Isl1(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669422|imex:IM-28774-1923 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067434.3|refseq:XP_006517596.1|ensembl:ENSMUSG00000042258(gene)|ensembl:ENSMUST00000036060(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0048880"(sensory system development)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0007409"(axonogenesis)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0007507"(heart development)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|mint:P61372|rcsb pdb:2RGT|rcsb pdb:4JCJ|interpro:IPR017970|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|entrezgene/locuslink:16392(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - function:Binds to one of the cis-acting domain of the insulin gene enhancer|comment:mint "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd010090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:9Mxwu/mS0Xtzm7MfJe1uM/1+zo0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61372 uniprotkb:P70662 intact:EBI-7988215|uniprotkb:P47894|uniprotkb:Q812D8|uniprotkb:P20663|intact:MINT-4594016|ensembl:ENSMUSP00000044879 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:isl1_mouse(display_long)|uniprotkb:Isl1(gene name)|psi-mi:Isl1(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669414|imex:IM-28774-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067434.3|refseq:XP_006517596.1|ensembl:ENSMUSG00000042258(gene)|ensembl:ENSMUST00000036060(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0048880"(sensory system development)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0007409"(axonogenesis)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0007507"(heart development)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|mint:P61372|rcsb pdb:2RGT|rcsb pdb:4JCJ|interpro:IPR017970|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|entrezgene/locuslink:16392(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - function:Binds to one of the cis-acting domain of the insulin gene enhancer|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd010090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:kZeTgLVQhus2lDAe9lG4B43RHTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70662 uniprotkb:Q01822 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 intact:EBI-26669376|ensembl:ENSMUSP00000043078|uniprotkb:Q0VBQ9 psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:hxd1_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.9(gene name synonym)|uniprotkb:Hoxd1(gene name)|psi-mi:Hoxd1(display_short)|uniprotkb:Hox-4.9(gene name synonym)|uniprotkb:Hoxd-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669406|imex:IM-28774-2781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) ensembl:ENSMUSG00000042448(gene)|ensembl:ENSMUST00000047793(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030182"(neuron differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034597.2|entrezgene/locuslink:15429(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rogid:AWFBn+n3uSyVvKTZDh4+9z37Wl810090 rigid:nWlOS5GmvuF42hSOhqRD0smM6HI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70662 uniprotkb:Q01822 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 intact:EBI-26669376|ensembl:ENSMUSP00000043078|uniprotkb:Q0VBQ9 psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:hxd1_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.9(gene name synonym)|uniprotkb:Hoxd1(gene name)|psi-mi:Hoxd1(display_short)|uniprotkb:Hox-4.9(gene name synonym)|uniprotkb:Hoxd-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669398|imex:IM-28774-3219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) ensembl:ENSMUSG00000042448(gene)|ensembl:ENSMUST00000047793(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030182"(neuron differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034597.2|entrezgene/locuslink:15429(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rogid:AWFBn+n3uSyVvKTZDh4+9z37Wl810090 rigid:nWlOS5GmvuF42hSOhqRD0smM6HI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70662 uniprotkb:O35137 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669368|imex:IM-28774-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:5TZysR7CQXwxoq0cUr6E2IVsh+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35638 uniprotkb:P18847 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669360|imex:IM-28774-3217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N|entrezgene/locuslink:467(identity) - crc64:31905293FB1FBBE2 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rigid:sEwU/XGL5HRs7UzuqDHStsWkOM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35638 uniprotkb:P53567 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 intact:EBI-740209|uniprotkb:Q5U052|ensembl:ENSP00000284000|ensembl:ENSP00000466022|ensembl:ENSP00000499062|uniprotkb:B2R946 psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:cebpg_human(display_long)|uniprotkb:CEBPG(gene name)|psi-mi:CEBPG(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669352|imex:IM-28774-2779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|ensembl:ENSG00000153879(gene)|ensembl:ENST00000284000(transcript)|ensembl:ENST00000585933(transcript)|ensembl:ENST00000652630(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001797.1|refseq:NP_001239225.1|entrezgene/locuslink:1054(identity) - crc64:31905293FB1FBBE2 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rogid:UneEv6RijykMEaPgr/apEUYxnJI9606 rigid:X1mCcMABH/M4LOPJcDeI2ZRqBCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35638 uniprotkb:Q15744 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669344|imex:IM-28774-1019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - crc64:31905293FB1FBBE2 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:UPg3oO35nn8uXqd9GCbXFL/lCMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62315 uniprotkb:Q61545 intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669336|imex:IM-28774-2381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N|entrezgene/locuslink:16468(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:8JUHYFxA5dHXa8xHE0gqO7S4Qnk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61179 uniprotkb:P09632 intact:EBI-646653|ensembl:ENSMUSP00000120359 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669328|imex:IM-28774-1921 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:y/xzFjAbfmdC3lXHm/fBDMC6ncE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61179 uniprotkb:P31315 intact:EBI-646653|ensembl:ENSMUSP00000120359 intact:EBI-26669291|ensembl:ENSMUSP00000069728 psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:gsx1_mouse(display_long)|uniprotkb:Homeobox protein GSH-1(gene name synonym)|uniprotkb:Gsx1(gene name)|psi-mi:Gsx1(display_short)|uniprotkb:Gsh-1(gene name synonym)|uniprotkb:Gsh1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669320|imex:IM-28774-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) ensembl:ENSMUSG00000053129(gene)|ensembl:ENSMUST00000065382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048663"(neuron fate commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_032204.1|entrezgene/locuslink:14842(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rogid:S9bUtK3Cd4bobZBaRACmwVAnJS010090 rigid:hzaFsgZmmfLONgFq5aaYReP8t1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61179 uniprotkb:Q04742 intact:EBI-646653|ensembl:ENSMUSP00000120359 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669283|imex:IM-28774-2379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:zoNFDWWUep23AoDMuQ5OsqLzpv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NA42 uniprotkb:Q01844 intact:EBI-20110775|uniprotkb:Q6X2C7|ensembl:ENSP00000340132|ensembl:ENSP00000464871|ensembl:ENSP00000466101|ensembl:ENSP00000507972 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:zn383_human(display_long)|uniprotkb:ZNF383(gene name)|psi-mi:ZNF383(display_short)|uniprotkb:HSD17(orf name) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669275|imex:IM-28774-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001332876.1|refseq:NP_001332877.1|refseq:NP_001332878.1|refseq:NP_689817.1|refseq:XP_005258642.1|refseq:XP_011524888.1|refseq:XP_011524889.1|refseq:XP_011524890.1|refseq:XP_011524891.1|refseq:XP_011524892.1|refseq:XP_016881911.1|refseq:XP_016881912.1|refseq:XP_016881913.1|reactome:R-HSA-212436|ensembl:ENSG00000188283(gene)|ensembl:ENST00000352998(transcript)|ensembl:ENST00000589413(transcript)|ensembl:ENST00000590503(transcript)|ensembl:ENST00000684119(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:163087(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rEXSrt9PLry+HjD800DRNd2k/zQ9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:Eaqee5BgtffiPbFWT3bNPOqhCcg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N184 uniprotkb:P61457 intact:EBI-749400|uniprotkb:Q6N044|uniprotkb:B3KX49|ensembl:ENSP00000441838|ensembl:ENSP00000507048 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zn567_human(display_long)|uniprotkb:ZNF567(gene name)|psi-mi:ZNF567(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669267|imex:IM-28774-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689816.2|refseq:XP_011524886.1|refseq:NP_001287908.1|refseq:NP_001309840.1|refseq:NP_001309841.1|refseq:NP_001309842.1|refseq:NP_001309843.1|refseq:NP_001309844.1|refseq:NP_001309845.1|refseq:NP_001309846.1|refseq:NP_001309847.1|refseq:NP_001309848.1|refseq:NP_001309849.1|refseq:XP_016881906.1|refseq:XP_016881907.1|refseq:XP_016881909.1|refseq:XP_016881910.1|ensembl:ENSG00000189042(gene)|ensembl:ENST00000536254(transcript)|ensembl:ENST00000682579(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q8N184|reactome:R-HSA-212436|entrezgene/locuslink:163081(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c91XZ0kJYsZ9Vdq3wmM+0/VgyZE9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:PICBeeWbDt9QXllM1vsAE7FCqdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXF8 uniprotkb:Q9BQY4 intact:EBI-5278558|uniprotkb:Q8NBR2|uniprotkb:Q8NES1|uniprotkb:Q8TAA8|uniprotkb:Q96D35|ensembl:ENSP00000470082|ensembl:ENSP00000471512 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 psi-mi:dedd2_human(display_long)|uniprotkb:DEDD2(gene name)|psi-mi:DEDD2(display_short)|uniprotkb:FLAME3(gene name synonym)|uniprotkb:DED-containing protein FLAME-3(gene name synonym)|uniprotkb:FADD-like anti-apoptotic molecule 3(gene name synonym)|uniprotkb:PSEC0004(orf name) psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669259|imex:IM-28774-2777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_579874.1|refseq:NP_001257543.1|refseq:NP_001257544.1|ensembl:ENSG00000160570(gene)|ensembl:ENST00000595337(transcript)|ensembl:ENST00000596251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR038856|mint:Q8WXF8|entrezgene/locuslink:162989(identity) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KEvs0YThfzCArmJwoQF/bHHttZk9606 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rigid:pUAow0L9qPKlYtJyHkuG0ixsCSw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXF8 uniprotkb:Q99729 intact:EBI-5278558|uniprotkb:Q8NBR2|uniprotkb:Q8NES1|uniprotkb:Q8TAA8|uniprotkb:Q96D35|ensembl:ENSP00000470082|ensembl:ENSP00000471512 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:dedd2_human(display_long)|uniprotkb:DEDD2(gene name)|psi-mi:DEDD2(display_short)|uniprotkb:FLAME3(gene name synonym)|uniprotkb:DED-containing protein FLAME-3(gene name synonym)|uniprotkb:FADD-like anti-apoptotic molecule 3(gene name synonym)|uniprotkb:PSEC0004(orf name) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669251|imex:IM-28774-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_579874.1|refseq:NP_001257543.1|refseq:NP_001257544.1|ensembl:ENSG00000160570(gene)|ensembl:ENST00000595337(transcript)|ensembl:ENST00000596251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR038856|mint:Q8WXF8|entrezgene/locuslink:162989(identity) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N|entrezgene/locuslink:3182(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KEvs0YThfzCArmJwoQF/bHHttZk9606 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:UTgGisr7HsygiRfECVjJXVXg4tQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXF8 uniprotkb:O43251 intact:EBI-5278558|uniprotkb:Q8NBR2|uniprotkb:Q8NES1|uniprotkb:Q8TAA8|uniprotkb:Q96D35|ensembl:ENSP00000470082|ensembl:ENSP00000471512 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:dedd2_human(display_long)|uniprotkb:DEDD2(gene name)|psi-mi:DEDD2(display_short)|uniprotkb:FLAME3(gene name synonym)|uniprotkb:DED-containing protein FLAME-3(gene name synonym)|uniprotkb:FADD-like anti-apoptotic molecule 3(gene name synonym)|uniprotkb:PSEC0004(orf name) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669243|imex:IM-28774-2775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_579874.1|refseq:NP_001257543.1|refseq:NP_001257544.1|ensembl:ENSG00000160570(gene)|ensembl:ENST00000595337(transcript)|ensembl:ENST00000596251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR038856|mint:Q8WXF8|entrezgene/locuslink:162989(identity) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KEvs0YThfzCArmJwoQF/bHHttZk9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:y/951O9penKazJ6p0GFLwChrZZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:Q8WXF8 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-5278558|uniprotkb:Q8NBR2|uniprotkb:Q8NES1|uniprotkb:Q8TAA8|uniprotkb:Q96D35|ensembl:ENSP00000470082|ensembl:ENSP00000471512 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:dedd2_human(display_long)|uniprotkb:DEDD2(gene name)|psi-mi:DEDD2(display_short)|uniprotkb:FLAME3(gene name synonym)|uniprotkb:DED-containing protein FLAME-3(gene name synonym)|uniprotkb:FADD-like anti-apoptotic molecule 3(gene name synonym)|uniprotkb:PSEC0004(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669235|imex:IM-28774-2773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) refseq:NP_579874.1|refseq:NP_001257543.1|refseq:NP_001257544.1|ensembl:ENSG00000160570(gene)|ensembl:ENST00000595337(transcript)|ensembl:ENST00000596251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR038856|mint:Q8WXF8|entrezgene/locuslink:162989(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:KEvs0YThfzCArmJwoQF/bHHttZk9606 rigid:1PDCj9TEN+XfkUD+K4EGmh6Jhz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88522 uniprotkb:O88522 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669219|imex:IM-28774-3215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:Jk0sEB5weZbqcc12sf+a+s5BwAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53776 uniprotkb:P70662 intact:EBI-26666200|ensembl:ENSMUSP00000027740|uniprotkb:O08916|uniprotkb:Q810K7|uniprotkb:Q9R280 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx4_mouse(display_long)|uniprotkb:Lhx4(gene name)|psi-mi:Lhx4(display_short)|uniprotkb:Gsh-4(gene name synonym)|uniprotkb:Gsh4(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669636|imex:IM-28774-2385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026468(gene)|ensembl:ENSMUST00000027740(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|refseq:NP_034842.2|entrezgene/locuslink:16872(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MK0SaLTxxzZ6TgZlXnEk1+pDECU10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:muHAwz2ZeCEgJWhFdjAGPK5gOTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61375 uniprotkb:P70662 intact:EBI-26669652|ensembl:ENSMUSP00000031591|uniprotkb:P50459 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx5_mouse(display_long)|uniprotkb:Lhx5(gene name)|psi-mi:Lhx5(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669682|imex:IM-28774-2785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029595(gene)|ensembl:ENSMUST00000031591(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021937"(cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_032525.1|entrezgene/locuslink:16873(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kMxtorElvFRhm9M3xVpgtNJX+BQ10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:niRvsXYuUPBBaLVgxgH1lQM6PTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53776 uniprotkb:O55203 intact:EBI-26666200|ensembl:ENSMUSP00000027740|uniprotkb:O08916|uniprotkb:Q810K7|uniprotkb:Q9R280 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx4_mouse(display_long)|uniprotkb:Lhx4(gene name)|psi-mi:Lhx4(display_short)|uniprotkb:Gsh-4(gene name synonym)|uniprotkb:Gsh4(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669644|imex:IM-28774-2783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026468(gene)|ensembl:ENSMUST00000027740(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|refseq:NP_034842.2|entrezgene/locuslink:16872(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MK0SaLTxxzZ6TgZlXnEk1+pDECU10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:VnzHqjzevvXUrGkjqCcTt/s17/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61375 uniprotkb:O55203 intact:EBI-26669652|ensembl:ENSMUSP00000031591|uniprotkb:P50459 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx5_mouse(display_long)|uniprotkb:Lhx5(gene name)|psi-mi:Lhx5(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669690|imex:IM-28774-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029595(gene)|ensembl:ENSMUST00000031591(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021937"(cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_032525.1|entrezgene/locuslink:16873(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kMxtorElvFRhm9M3xVpgtNJX+BQ10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:dHL4VB9fMfyjjZVVSCXfIl8qH2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUH2 uniprotkb:P70662 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669706|imex:IM-28774-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:yfSJ5essJ/lfthReKiJmilVcCEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUH2 uniprotkb:P70662 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669698|imex:IM-28774-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:yfSJ5essJ/lfthReKiJmilVcCEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUH2 uniprotkb:O55203 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669714|imex:IM-28774-1025 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:J86zyZJLGiOf2y+vHy0xKkNcOOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P43136 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669945|imex:IM-28774-1493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:13864(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rigid:JvLPYol6H7HGjFXKSZnrf9gnmRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUH2 uniprotkb:O55203 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669722|imex:IM-28774-2387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:J86zyZJLGiOf2y+vHy0xKkNcOOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P70396 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669929|imex:IM-28774-2393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rigid:Kao3y5/A8gKWpACFDDPV7m5ftZw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P70436 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-1801333|uniprotkb:Q3UM51|uniprotkb:Q8R4I3|ensembl:ENSMUSP00000021241 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx4_mouse(display_long)|uniprotkb:Dlx4(gene name)|psi-mi:Dlx4(display_short)|uniprotkb:Dlx7(gene name synonym)|uniprotkb:Homeobox protein DLX-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669921|imex:IM-28774-2795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) refseq:NP_031893.3|ensembl:ENSMUSG00000020871(gene)|ensembl:ENSMUST00000021241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:13394(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:qdYVFVDe+39K0nv/Gz2X5WexmHg10090 rigid:KTAMEAgueSYSNjQsbYqgFuTZ1pE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P70436 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-1801333|uniprotkb:Q3UM51|uniprotkb:Q8R4I3|ensembl:ENSMUSP00000021241 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx4_mouse(display_long)|uniprotkb:Dlx4(gene name)|psi-mi:Dlx4(display_short)|uniprotkb:Dlx7(gene name synonym)|uniprotkb:Homeobox protein DLX-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669913|imex:IM-28774-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) refseq:NP_031893.3|ensembl:ENSMUSG00000020871(gene)|ensembl:ENSMUST00000021241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:13394(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:qdYVFVDe+39K0nv/Gz2X5WexmHg10090 rigid:KTAMEAgueSYSNjQsbYqgFuTZ1pE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P40764 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-26668537|ensembl:ENSMUSP00000024159 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx2_mouse(display_long)|uniprotkb:Homeobox protein TES-1(gene name synonym)|uniprotkb:Dlx2(gene name)|psi-mi:Dlx2(display_short)|uniprotkb:Tes-1(gene name synonym)|uniprotkb:Tes1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669905|imex:IM-28774-2391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|ensembl:ENSMUSG00000023391(gene)|ensembl:ENSMUST00000024159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0051216"(cartilage development)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|refseq:NP_034184.1|entrezgene/locuslink:13392(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:UiMEIffYTfo4n1rQRSlJ+B4MG8c10090 rigid:X9G8KXKpWld9LJ1hOHYBNQ5J80Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:Q64317 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669897|imex:IM-28774-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:ohE9sVehMN4eZi9Cup7fiukQQw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:Q64317 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669889|imex:IM-28774-3221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:ohE9sVehMN4eZi9Cup7fiukQQw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWG4 uniprotkb:O43679 intact:EBI-744719|ensembl:ENSP00000270061|uniprotkb:Q9BWW5 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:ssbp4_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669881|imex:IM-28774-1933 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130511(gene)|ensembl:ENST00000270061(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWG4|refseq:NP_001009998.1|refseq:NP_116016.1|entrezgene/locuslink:170463(identity) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|entrezgene/locuslink:9079(identity) - - crc64:E86387BA027F383A figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0T7Xjz4MbjSZpCzJlpGVFbFYy89606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:r35dgmg22ap7UdBP/tP4VMN5HGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWG4 uniprotkb:Q92481 intact:EBI-744719|ensembl:ENSP00000270061|uniprotkb:Q9BWW5 intact:EBI-725275|uniprotkb:Q5JYX6|uniprotkb:Q9NQ63|uniprotkb:Q9NU99|uniprotkb:Q9UJI7|uniprotkb:Q9Y214|uniprotkb:Q9Y3K3|ensembl:ENSP00000377265 psi-mi:ssbp4_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short) psi-mi:ap2b_human(display_long)|uniprotkb:Activating enhancer-binding protein 2-beta(gene name synonym)|uniprotkb:TFAP2B(gene name)|psi-mi:TFAP2B(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669873|imex:IM-28774-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130511(gene)|ensembl:ENST00000270061(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWG4|refseq:NP_001009998.1|refseq:NP_116016.1|entrezgene/locuslink:170463(identity) refseq:NP_003212.2|refseq:XP_011513139.1|ensembl:ENST00000393655(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0097276"(cellular creatinine homeostasis)|go:"GO:0097277"(cellular urea homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008122(Transcription factor AP-2 beta, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|reactome:R-HSA-3232118|reactome:R-HSA-8866904|reactome:R-HSA-8866907|reactome:R-HSA-8866910|go:"GO:0010842"(retina layer formation)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043588"(skin development)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055062"(phosphate ion homeostasis)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072210"(metanephric nephron development)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0097275"(cellular ammonium homeostasis)|ensembl:ENSG00000008196(gene)|entrezgene/locuslink:7021(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0T7Xjz4MbjSZpCzJlpGVFbFYy89606 rogid:nD3C+YodBUsGSz1Ggw2nVaQMsJQ9606 rigid:zR2AQ0BG+xPmACxFXjvmxJzA/Ic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWG4 uniprotkb:P61371 intact:EBI-744719|ensembl:ENSP00000270061|uniprotkb:Q9BWW5 intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658 psi-mi:ssbp4_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short) psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669865|imex:IM-28774-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130511(gene)|ensembl:ENST00000270061(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWG4|refseq:NP_001009998.1|refseq:NP_116016.1|entrezgene/locuslink:170463(identity) refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0T7Xjz4MbjSZpCzJlpGVFbFYy89606 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606 rigid:o11kW0CUK7hBUrXncbPXZLgyjos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NEA6 uniprotkb:Q9UMX1 intact:EBI-744456|uniprotkb:B1AL19|uniprotkb:Q1PHK5|ensembl:ENSP00000325494|ensembl:ENSP00000507306 intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918 psi-mi:glis3_human(display_long)|uniprotkb:GLI-similar 3(gene name synonym)|uniprotkb:Zinc finger protein 515(gene name synonym)|uniprotkb:GLIS3(gene name)|psi-mi:GLIS3(display_short)|uniprotkb:ZNF515(gene name synonym) psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669857|imex:IM-28774-1931 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035878.1|refseq:NP_689842.3|refseq:XP_011516065.1|refseq:XP_011516066.1|refseq:XP_011516068.1|ensembl:ENSP00000325494|ensembl:ENST00000381971|ensembl:ENSP00000371398|ensembl:ENSP00000507306|refseq:XP_005251443.1|ensembl:ENSG00000107249(gene)|ensembl:ENST00000324333(transcript)|ensembl:ENST00000682749(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030405|interpro:IPR036236|interpro:IPR043359|mint:Q8NEA6|refseq:XP_016869850.1|entrezgene/locuslink:169792(identity) refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|entrezgene/locuslink:51684(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Lw/ndmcKfz+wO+0eEheRj4Y0fXM9606 rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606 rigid:0Yvq2mtTzDU6TQEGLr2DNxNXmMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NEA6 uniprotkb:Q9UMX1 intact:EBI-744456|uniprotkb:B1AL19|uniprotkb:Q1PHK5|ensembl:ENSP00000325494|ensembl:ENSP00000507306 intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918 psi-mi:glis3_human(display_long)|uniprotkb:GLI-similar 3(gene name synonym)|uniprotkb:Zinc finger protein 515(gene name synonym)|uniprotkb:GLIS3(gene name)|psi-mi:GLIS3(display_short)|uniprotkb:ZNF515(gene name synonym) psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669849|imex:IM-28774-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035878.1|refseq:NP_689842.3|refseq:XP_011516065.1|refseq:XP_011516066.1|refseq:XP_011516068.1|ensembl:ENSP00000325494|ensembl:ENST00000381971|ensembl:ENSP00000371398|ensembl:ENSP00000507306|refseq:XP_005251443.1|ensembl:ENSG00000107249(gene)|ensembl:ENST00000324333(transcript)|ensembl:ENST00000682749(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030405|interpro:IPR036236|interpro:IPR043359|mint:Q8NEA6|refseq:XP_016869850.1|entrezgene/locuslink:169792(identity) refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|entrezgene/locuslink:51684(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Lw/ndmcKfz+wO+0eEheRj4Y0fXM9606 rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606 rigid:0Yvq2mtTzDU6TQEGLr2DNxNXmMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88609 uniprotkb:O55203 intact:EBI-13951208|uniprotkb:Q0VEN6 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669841|imex:IM-28774-2793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:AbVUwIBQTy2AYvrAoapbcB1IXDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88609 uniprotkb:O55203 intact:EBI-13951208|uniprotkb:Q0VEN6 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669833|imex:IM-28774-2791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:AbVUwIBQTy2AYvrAoapbcB1IXDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88609 uniprotkb:P70662 intact:EBI-13951208|uniprotkb:Q0VEN6 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669825|imex:IM-28774-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:eJgF/vs3TJac9tkSwMtn2lQYTLQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88609 uniprotkb:P70662 intact:EBI-13951208|uniprotkb:Q0VEN6 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669817|imex:IM-28774-1491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:eJgF/vs3TJac9tkSwMtn2lQYTLQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88609 uniprotkb:O35137 intact:EBI-13951208|uniprotkb:Q0VEN6 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669809|imex:IM-28774-1489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:gBVEA4Q1SYd7RIXKIJx3hwT80nU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88609 uniprotkb:O35137 intact:EBI-13951208|uniprotkb:Q0VEN6 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669801|imex:IM-28774-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:gBVEA4Q1SYd7RIXKIJx3hwT80nU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61969 uniprotkb:O55203 intact:EBI-26669746|ensembl:ENSMUSP00000113513|ensembl:ENSMUSP00000113840|ensembl:ENSMUSP00000113865|uniprotkb:O00158|uniprotkb:O88894 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:lmo4_mouse(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:Lmo4(gene name)|psi-mi:Lmo4(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669793|imex:IM-28774-2389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028266(gene)|ensembl:ENSMUST00000120539(transcript)|ensembl:ENSMUST00000121112(transcript)|ensembl:ENSMUST00000121796(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0050865"(regulation of cell activation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2DFY|rcsb pdb:2MBV|refseq:NP_001155241.1|refseq:NP_001155242.1|refseq:NP_034853.1|entrezgene/locuslink:16911(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:yABBlQc2MmENOiop2EJizij1zLQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61969 uniprotkb:P70662 intact:EBI-26669746|ensembl:ENSMUSP00000113513|ensembl:ENSMUSP00000113840|ensembl:ENSMUSP00000113865|uniprotkb:O00158|uniprotkb:O88894 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:lmo4_mouse(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:Lmo4(gene name)|psi-mi:Lmo4(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669785|imex:IM-28774-2789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028266(gene)|ensembl:ENSMUST00000120539(transcript)|ensembl:ENSMUST00000121112(transcript)|ensembl:ENSMUST00000121796(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0050865"(regulation of cell activation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2DFY|rcsb pdb:2MBV|refseq:NP_001155241.1|refseq:NP_001155242.1|refseq:NP_034853.1|entrezgene/locuslink:16911(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:JLaEuCQDJ1MfAIIwLcZwfIQOKdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25801 uniprotkb:O55203 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669738|imex:IM-28774-2787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD|entrezgene/locuslink:16909(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:NSM9t0abZ+kCYzj495KltbVScS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25801 uniprotkb:P70662 intact:EBI-3903256|ensembl:ENSMUSP00000117703|ensembl:ENSMUSP00000128317 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:rbtn2_mouse(display_long)|uniprotkb:Lmo2(gene name)|psi-mi:Lmo2(display_short)|uniprotkb:Rbtn-2(gene name synonym)|uniprotkb:Rbtn2(gene name synonym)|uniprotkb:Rhom-2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669730|imex:IM-28774-1929 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135808.1|refseq:NP_001135809.1|dip:DIP-24247N|refseq:XP_006498883.1|ensembl:ENSMUSG00000032698(gene)|ensembl:ENSMUST00000123437(transcript)|ensembl:ENSMUST00000170926(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P25801|rcsb pdb:1J2O|rcsb pdb:2L6Y|rcsb pdb:2L6Z|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-8939236|rcsb pdb:2LXD|entrezgene/locuslink:16909(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kIZ60YCK4hzGaxmi6+zOSaMDlNY10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:CUejHTgS9Tyi7xsbgx8XG9xcFdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P70396 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669937|imex:IM-28774-2395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rigid:Kao3y5/A8gKWpACFDDPV7m5ftZw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05BA5 uniprotkb:O88522 intact:EBI-5745783|ensembl:ENSMUSP00000085416 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670328|imex:IM-28774-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:qQi2dizE2xUY73+paroBD6vzff4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61127 uniprotkb:P08046 intact:EBI-2366420|uniprotkb:Q80VR9|ensembl:ENSMUSP00000026469 intact:EBI-11291629|uniprotkb:Q61777|ensembl:ENSMUSP00000069616|ensembl:ENSMUSP00000126931 psi-mi:nab2_mouse(display_long)|uniprotkb:Nab2(gene name)|psi-mi:Nab2(display_short)|uniprotkb:EGR-1-binding protein 2(gene name synonym) psi-mi:egr1_mouse(display_long)|uniprotkb:Egr1(gene name)|psi-mi:Egr1(display_short)|uniprotkb:Egr-1(gene name synonym)|uniprotkb:Krox-24(gene name synonym)|uniprotkb:Nerve growth factor-induced protein A(gene name synonym)|uniprotkb:Transcription factor Zif268(gene name synonym)|uniprotkb:Zinc finger protein Krox-24(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670320|imex:IM-28774-2799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116367.1|refseq:NP_032694.2|ensembl:ENSMUSG00000025402(gene)|ensembl:ENSMUST00000026469(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038398|interpro:IPR039040|mint:Q61127|reactome:R-MMU-9031628|entrezgene/locuslink:17937(identity) refseq:NP_031939.1|ensembl:ENSMUSG00000038418(gene)|ensembl:ENSMUST00000064795(transcript)|ensembl:ENSMUST00000165033(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033233"(regulation of protein sumoylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071506"(cellular response to mycophenolic acid)|go:"GO:0072110"(glomerular mesangial cell proliferation)|go:"GO:0072303"(positive regulation of glomerular metanephric mesangial cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098759"(cellular response to interleukin-8)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000182"(regulation of progesterone biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021839|interpro:IPR021849|interpro:IPR036236|rcsb pdb:1A1F|rcsb pdb:1A1G|rcsb pdb:1A1H|rcsb pdb:1A1I|rcsb pdb:1A1J|rcsb pdb:1A1K|rcsb pdb:1A1L|rcsb pdb:1AAY|rcsb pdb:1F2I|rcsb pdb:1G2D|rcsb pdb:1G2F|rcsb pdb:1JK1|rcsb pdb:1JK2|rcsb pdb:1LLM|rcsb pdb:1P47|rcsb pdb:1ZAA|entrezgene/locuslink:13653(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rf3ukqRbH6FRLzgfVxvpwEl9Kvc10090 rogid:Zzqbrs/khNbZMa+jrrJmFevL3Ec10090 rigid:fSI5I/+etEXL8lh376ZVVkmqGKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10085 uniprotkb:Q6GTZ3 intact:EBI-4405734|uniprotkb:Q8C6B1|ensembl:ENSMUSP00000072330 intact:EBI-26669132 psi-mi:myod1_mouse(display_long)|uniprotkb:Myod1(gene name)|psi-mi:Myod1(display_short)|uniprotkb:Myod(gene name synonym) psi-mi:q6gtz3_mouse(display_long)|uniprotkb:Id1(gene name)|psi-mi:Id1(display_short)|uniprotkb:Idb1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670312|imex:IM-28774-2797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034996.2|dip:DIP-37N|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014902"(myotube differentiation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|ensembl:ENSMUSG00000009471(gene)|ensembl:ENSMUST00000072514(transcript)|interpro:IPR036638|interpro:IPR039704|mint:P10085|rcsb pdb:1MDY|reactome:R-MMU-525793|interpro:IPR022032|entrezgene/locuslink:17927(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_034625.1|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15901(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9GpR7O8xYPiQXHqrlxB/HioqgJM10090 rogid:IRUXStmLzIzQ5jb8Aw8r0MhfKPc10090 rigid:K4oFuVGb4X2q4gpnMfufFPBiYNg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01108 uniprotkb:P28574 intact:EBI-1183114|uniprotkb:P70247|uniprotkb:Q3UM70|uniprotkb:Q61422|ensembl:ENSMUSP00000123821|ensembl:ENSMUSP00000123852|ensembl:ENSMUSP00000124758 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 psi-mi:myc_mouse(display_long)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:Myc(gene name)|psi-mi:Myc(display_short) psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670304|imex:IM-28774-1941 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170823.1|refseq:NP_001170824.1|refseq:NP_001170825.1|ensembl:ENSMUSG00000022346(gene)|ensembl:ENSMUST00000159327(transcript)|ensembl:ENSMUST00000160009(transcript)|ensembl:ENSMUST00000161976(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006848"(pyruvate transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009314"(response to radiation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016485"(protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043473"(pigmentation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044337"(canonical Wnt signaling pathway involved in positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0003677"(DNA binding)|go:"GO:0000165"(MAPK cascade)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046722"(lactic acid secretion)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-MMU-5689880|reactome:R-MMU-8866911|reactome:R-MMU-9018519|dip:DIP-1064N|entrezgene/locuslink:17869(identity) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N|entrezgene/locuslink:17187(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nmDkyD4dlB5zKDpuzjv+JEpHZS410090 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rigid:ECfgeJZo7Yn0fQOKFoFtNaZD77A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02395 uniprotkb:Q61545 intact:EBI-2531578|uniprotkb:Q569Z8|uniprotkb:Q6PG89|uniprotkb:Q8BGP9|uniprotkb:Q8BSJ7|ensembl:ENSMUSP00000080278|uniprotkb:Q05C61 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:mtf2_mouse(display_long)|uniprotkb:Mtf2(gene name)|psi-mi:Mtf2(display_short)|uniprotkb:Pcl2(gene name synonym)|uniprotkb:Zinc-regulated factor 1(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670296|imex:IM-28774-2401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240806.1|refseq:NP_001240807.1|refseq:NP_001240808.1|refseq:NP_001240809.1|ensembl:ENSMUSG00000029267(gene)|ensembl:ENSMUST00000081567(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042014|rcsb pdb:2EQJ|rcsb pdb:2YT5|reactome:R-MMU-212300|interpro:IPR042015|refseq:XP_011247718.1|refseq:NP_038855.2|refseq:XP_017176193.1|refseq:XP_017176194.1|dip:DIP-56991N|entrezgene/locuslink:17765(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kBGqJsYOFZWUzaGEEm3h5zMcYR010090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:erNusj3U2wiJh8aS5oS70uW/jgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97367 uniprotkb:Q04742 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670288|imex:IM-28774-3227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:/YD7IhXBLoPWXnuzIGyl4Q1Bzeo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32443 uniprotkb:P09027 intact:EBI-26670247|ensembl:ENSMUSP00000043587|uniprotkb:Q544T6 intact:EBI-26667584|ensembl:ENSMUSP00000044809|ensembl:ENSMUSP00000107613|ensembl:ENSMUSP00000107614|uniprotkb:Q3UUD3 psi-mi:meox2_mouse(display_long)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Meox2(gene name)|psi-mi:Meox2(display_short)|uniprotkb:Gax(gene name synonym)|uniprotkb:Mox-2(gene name synonym)|uniprotkb:Mox2(gene name synonym) psi-mi:hxd3_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.1(gene name synonym)|uniprotkb:Homeobox protein MH-19(gene name synonym)|uniprotkb:Hoxd3(gene name)|psi-mi:Hoxd3(display_short)|uniprotkb:Hox-4.1(gene name synonym)|uniprotkb:Hoxd-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670280|imex:IM-28774-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensembl:ENSMUSG00000036144(gene)|ensembl:ENSMUST00000041183(transcript)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_032610.1|entrezgene/locuslink:17286(identity) ensembl:ENSMUSG00000079277(gene)|ensembl:ENSMUST00000047830(transcript)|ensembl:ENSMUST00000111982(transcript)|ensembl:ENSMUST00000111983(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|go:"GO:0051216"(cartilage development)|refseq:NP_034598.2|entrezgene/locuslink:15434(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ubOalBHxttPOs8Fjii/bAUvcgSw10090 rogid:o47Zd1IWzICvHRhhGN4cN2AQ+r010090 rigid:FKyySoBf7NXKVBOBQRTlShwmiHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60954 uniprotkb:P23812 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670239|imex:IM-28774-2399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:gF1YTN4KK1hEg23ZqJNu/76oL1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60954 uniprotkb:P09632 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670231|imex:IM-28774-1939 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:V98F27L5q//pzK5nmzgKKlmMBDA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60954 uniprotkb:P09631 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670223|imex:IM-28774-1503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:/roxqj9OokQca3Xjv60+m2IMwH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60954 uniprotkb:P09021 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 intact:EBI-925394|uniprotkb:Q91VQ5|ensembl:ENSMUSP00000039012 psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:hxa5_mouse(display_long)|uniprotkb:Hoxa5(gene name)|psi-mi:Hoxa5(display_short)|uniprotkb:Hox-1.3(gene name synonym)|uniprotkb:Hoxa-5(gene name synonym)|uniprotkb:Homeobox protein Hox-1.3(gene name synonym)|uniprotkb:Homeobox protein M2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670215|imex:IM-28774-1033 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) refseq:NP_034583.1|ensembl:ENSMUSG00000038253(gene)|ensembl:ENSMUST00000048794(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060481"(lobar bronchus epithelium development)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P09021|entrezgene/locuslink:15402(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rogid:1/djC9dlDssHzy1+X3zilRD+NPs10090 rigid:KeoYZKlCJKdc6n3g3qqCo2ODj6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2D6 uniprotkb:Q61545 intact:EBI-1188816|uniprotkb:Q3TYG1|uniprotkb:B1AUZ2|uniprotkb:B1AUZ3|ensembl:ENSMUSP00000098314|ensembl:ENSMUSP00000127115 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:mecp2_mouse(display_long)|uniprotkb:Mecp2(gene name)|psi-mi:Mecp2(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670207|imex:IM-28774-1031 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001075448.1|refseq:NP_034918.1|ensembl:ENSMUSG00000031393(gene)|ensembl:ENSMUST00000100750(transcript)|ensembl:ENSMUST00000170481(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042220"(response to cocaine)|go:"GO:0042551"(neuron maturation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071317"(cellular response to isoquinoline alkaloid)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1901956"(positive regulation of retrograde dense core granule transport)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905492"(positive regulation of branching morphogenesis of a nerve)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:Q9Z2D6|rcsb pdb:5NAF|reactome:R-MMU-9022692|go:"GO:0010385"(double-stranded methylated DNA binding)|dip:DIP-39984N|entrezgene/locuslink:17257(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+kDY0EPkyG+tTLMlP0zZFOS1R3E10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:PUhFqBqjhr+oxn/o4Dj8HVNazDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28574 uniprotkb:P10166 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 intact:EBI-26670173|ensembl:ENSMUSP00000030407|ensembl:ENSMUSP00000101859|uniprotkb:Q5FWI7 psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:mycl_mouse(display_long)|uniprotkb:Mycl(gene name)|psi-mi:Mycl(display_short)|uniprotkb:Lmyc1(gene name synonym)|uniprotkb:Mycl1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670199|imex:IM-28774-2397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N|entrezgene/locuslink:17187(identity) ensembl:ENSMUSG00000028654(gene)|ensembl:ENSMUST00000030407(transcript)|ensembl:ENSMUST00000106252(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|refseq:NP_001290050.1|refseq:NP_032532.1|refseq:XP_006502884.1|entrezgene/locuslink:16918(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rogid:8qSMVx++tzH/RjsmuMkzbU2auFw10090 rigid:6PvD6gNTO89Na6RNfnYyFnWtS24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TF68 uniprotkb:P31274 intact:EBI-6115971|uniprotkb:O15407|uniprotkb:Q7Z722|uniprotkb:Q8N938|ensembl:ENSP00000354592|ensembl:ENSP00000380019 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:zn384_human(display_long)|uniprotkb:ZNF384(gene name)|psi-mi:ZNF384(display_short)|uniprotkb:CAGH1(gene name synonym)|uniprotkb:CIZ(gene name synonym)|uniprotkb:NMP4(gene name synonym)|uniprotkb:TNRC1(gene name synonym)|uniprotkb:CAG repeat protein 1(gene name synonym)|uniprotkb:CAS-interacting zinc finger protein(gene name synonym)|uniprotkb:Nuclear matrix transcription factor 4(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 1 protein(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670165|imex:IM-28774-1501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000319770|ensembl:ENSP00000321650|ensembl:ENSP00000354592|ensembl:ENSP00000380019|ensembl:ENST00000355772|ensembl:ENSP00000348018|refseq:NP_001035009.1|refseq:NP_001129206.1|refseq:NP_597733.2|refseq:XP_016874430.1|refseq:XP_016874431.1|refseq:XP_016874432.1|refseq:XP_016874438.1|refseq:XP_016874439.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8TF68|ensembl:ENSG00000126746(gene)|ensembl:ENST00000361959(transcript)|ensembl:ENST00000396801(transcript)|entrezgene/locuslink:171017(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6TO45205H9niXg8StUmIooVLC289606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:KG8a341hT49JTsAQJI1TLneinhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TF68 uniprotkb:Q15744 intact:EBI-6115971|uniprotkb:O15407|uniprotkb:Q7Z722|uniprotkb:Q8N938|ensembl:ENSP00000354592|ensembl:ENSP00000380019 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:zn384_human(display_long)|uniprotkb:ZNF384(gene name)|psi-mi:ZNF384(display_short)|uniprotkb:CAGH1(gene name synonym)|uniprotkb:CIZ(gene name synonym)|uniprotkb:NMP4(gene name synonym)|uniprotkb:TNRC1(gene name synonym)|uniprotkb:CAG repeat protein 1(gene name synonym)|uniprotkb:CAS-interacting zinc finger protein(gene name synonym)|uniprotkb:Nuclear matrix transcription factor 4(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 1 protein(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670157|imex:IM-28774-1937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000319770|ensembl:ENSP00000321650|ensembl:ENSP00000354592|ensembl:ENSP00000380019|ensembl:ENST00000355772|ensembl:ENSP00000348018|refseq:NP_001035009.1|refseq:NP_001129206.1|refseq:NP_597733.2|refseq:XP_016874430.1|refseq:XP_016874431.1|refseq:XP_016874432.1|refseq:XP_016874438.1|refseq:XP_016874439.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8TF68|ensembl:ENSG00000126746(gene)|ensembl:ENST00000361959(transcript)|ensembl:ENST00000396801(transcript)|entrezgene/locuslink:171017(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6TO45205H9niXg8StUmIooVLC289606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:1xzy+sgfU4qvpZE/Bf0NcoME478 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VH51 uniprotkb:Q9WUL8 intact:EBI-644098|uniprotkb:Q5RJI0|uniprotkb:Q99KV0|ensembl:ENSMUSP00000105216 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:rbm39_mouse(display_long)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Coactivator of activating protein 1 and estrogen receptors(gene name synonym)|uniprotkb:Rbm39(gene name)|psi-mi:Rbm39(display_short)|uniprotkb:Caper(gene name synonym)|uniprotkb:Rnpc2(gene name synonym) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670149|imex:IM-28774-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573505.2|ensembl:ENSMUSG00000027620(gene)|ensembl:ENSMUST00000109587(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q8VH51|rcsb pdb:2LQ5|rcsb pdb:3S6E|rcsb pdb:4J5O|rcsb pdb:4RU2|rcsb pdb:5CXT|refseq:XP_011237629.1|refseq:NP_001278043.1|refseq:NP_001278044.1|refseq:XP_017171483.1|refseq:XP_017171494.1|refseq:XP_017171497.1|refseq:XP_011237628.1|refseq:XP_017171487.1|entrezgene/locuslink:170791(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dW5PuXllczFeyQ6ask6CFrukMKk10090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:o3eME9k+HaQKtkG1oHQQh1QlI3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VH51 uniprotkb:Q9JL10 intact:EBI-644098|uniprotkb:Q5RJI0|uniprotkb:Q99KV0|ensembl:ENSMUSP00000105216 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 psi-mi:rbm39_mouse(display_long)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Coactivator of activating protein 1 and estrogen receptors(gene name synonym)|uniprotkb:Rbm39(gene name)|psi-mi:Rbm39(display_short)|uniprotkb:Caper(gene name synonym)|uniprotkb:Rnpc2(gene name synonym) psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670141|imex:IM-28774-1499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573505.2|ensembl:ENSMUSG00000027620(gene)|ensembl:ENSMUST00000109587(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q8VH51|rcsb pdb:2LQ5|rcsb pdb:3S6E|rcsb pdb:4J5O|rcsb pdb:4RU2|rcsb pdb:5CXT|refseq:XP_011237629.1|refseq:NP_001278043.1|refseq:NP_001278044.1|refseq:XP_017171483.1|refseq:XP_017171494.1|refseq:XP_017171497.1|refseq:XP_011237628.1|refseq:XP_017171487.1|entrezgene/locuslink:170791(identity) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dW5PuXllczFeyQ6ask6CFrukMKk10090 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rigid:9P9I+h7vTdgF7NzF+7IUxkh/haM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VH51 uniprotkb:Q60749 intact:EBI-644098|uniprotkb:Q5RJI0|uniprotkb:Q99KV0|ensembl:ENSMUSP00000105216 intact:EBI-519077|uniprotkb:A2ACH3|uniprotkb:Q7M4N5|uniprotkb:Q3U8T3|uniprotkb:Q60735|uniprotkb:Q99M33|ensembl:ENSMUSP00000066516|ensembl:ENSMUSP00000115402|uniprotkb:B2KG38 psi-mi:rbm39_mouse(display_long)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Coactivator of activating protein 1 and estrogen receptors(gene name synonym)|uniprotkb:Rbm39(gene name)|psi-mi:Rbm39(display_short)|uniprotkb:Caper(gene name synonym)|uniprotkb:Rnpc2(gene name synonym) psi-mi:khdr1_mouse(display_long)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:Khdrbs1(gene name)|psi-mi:Khdrbs1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670114|imex:IM-28774-1029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573505.2|ensembl:ENSMUSG00000027620(gene)|ensembl:ENSMUST00000109587(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q8VH51|rcsb pdb:2LQ5|rcsb pdb:3S6E|rcsb pdb:4J5O|rcsb pdb:4RU2|rcsb pdb:5CXT|refseq:XP_011237629.1|refseq:NP_001278043.1|refseq:NP_001278044.1|refseq:XP_017171483.1|refseq:XP_017171494.1|refseq:XP_017171497.1|refseq:XP_011237628.1|refseq:XP_017171487.1|entrezgene/locuslink:170791(identity) ensembl:ENSMUSG00000028790(gene)|ensembl:ENSMUST00000066257(transcript)|ensembl:ENSMUST00000129342(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q60749|reactome:R-MMU-8849468|refseq:NP_035447.3|dip:DIP-2861N|entrezgene/locuslink:20218(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dW5PuXllczFeyQ6ask6CFrukMKk10090 rogid:FtKudvPZeoFATHi0fUbnPsJgons10090 rigid:POOO3g0qTTSMWGHXjqnoOArvWi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VH51 uniprotkb:P31245 intact:EBI-644098|uniprotkb:Q5RJI0|uniprotkb:Q99KV0|ensembl:ENSMUSP00000105216 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:rbm39_mouse(display_long)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Coactivator of activating protein 1 and estrogen receptors(gene name synonym)|uniprotkb:Rbm39(gene name)|psi-mi:Rbm39(display_short)|uniprotkb:Caper(gene name synonym)|uniprotkb:Rnpc2(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670106|imex:IM-28774-1497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573505.2|ensembl:ENSMUSG00000027620(gene)|ensembl:ENSMUST00000109587(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q8VH51|rcsb pdb:2LQ5|rcsb pdb:3S6E|rcsb pdb:4J5O|rcsb pdb:4RU2|rcsb pdb:5CXT|refseq:XP_011237629.1|refseq:NP_001278043.1|refseq:NP_001278044.1|refseq:XP_017171483.1|refseq:XP_017171494.1|refseq:XP_017171497.1|refseq:XP_011237628.1|refseq:XP_017171487.1|entrezgene/locuslink:170791(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dW5PuXllczFeyQ6ask6CFrukMKk10090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:TSXmHq8bIZBmhC6M3qT3dxGFwsw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P3E7 uniprotkb:G3X904 intact:EBI-11707298|uniprotkb:G3X9I8|ensembl:ENSMUSP00000080832 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:hda10_mouse(display_long)|uniprotkb:Histone deacetylase 10(gene name synonym)|uniprotkb:Hdac10(gene name)|psi-mi:Hdac10(display_short) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670098|imex:IM-28774-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_954668.2|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|ensembl:ENSMUSG00000062906(gene)|ensembl:ENSMUST00000082197(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|entrezgene/locuslink:170787(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DahoUwe9Em+xnUFMmwG8mLiA4UY10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:wSLxn7zO3/XvJCrSPgTZ+gwGHo0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63015 uniprotkb:Q6P3E7 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 intact:EBI-11707298|uniprotkb:G3X9I8|ensembl:ENSMUSP00000080832 psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:hda10_mouse(display_long)|uniprotkb:Histone deacetylase 10(gene name synonym)|uniprotkb:Hdac10(gene name)|psi-mi:Hdac10(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670090|imex:IM-28774-1495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like)|entrezgene/locuslink:18508(identity) refseq:NP_954668.2|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|ensembl:ENSMUSG00000062906(gene)|ensembl:ENSMUST00000082197(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|entrezgene/locuslink:170787(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 rogid:DahoUwe9Em+xnUFMmwG8mLiA4UY10090 rigid:iJ43B/6wrDTMRQcolkBF6yG1M64 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P3E7 uniprotkb:Q61545 intact:EBI-11707298|uniprotkb:G3X9I8|ensembl:ENSMUSP00000080832 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:hda10_mouse(display_long)|uniprotkb:Histone deacetylase 10(gene name synonym)|uniprotkb:Hdac10(gene name)|psi-mi:Hdac10(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670082|imex:IM-28774-1935 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_954668.2|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|ensembl:ENSMUSG00000062906(gene)|ensembl:ENSMUST00000082197(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|entrezgene/locuslink:170787(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DahoUwe9Em+xnUFMmwG8mLiA4UY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:v4a4+U4ZsTQb7DhB01qN+5BNYyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P3E7 uniprotkb:F8VPR5 intact:EBI-11707298|uniprotkb:G3X9I8|ensembl:ENSMUSP00000080832 intact:EBI-10989694|ensembl:ENSMUSP00000023165 psi-mi:hda10_mouse(display_long)|uniprotkb:Histone deacetylase 10(gene name synonym)|uniprotkb:Hdac10(gene name)|psi-mi:Hdac10(display_short) psi-mi:f8vpr5_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670074|imex:IM-28774-1027 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_954668.2|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|ensembl:ENSMUSG00000062906(gene)|ensembl:ENSMUST00000082197(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|entrezgene/locuslink:170787(identity) refseq:NP_001020603.1|ensembl:ENSMUSG00000022521(gene)|ensembl:ENSMUST00000023165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:12914(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DahoUwe9Em+xnUFMmwG8mLiA4UY10090 rogid:9K1igrA8QbILB/vG1/XLKh9kzJM10090 rigid:aNOpSaKHqhfOzqtCJGL5Z48r9LI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6T264 uniprotkb:Q6P3E7 intact:EBI-7650924|ensembl:ENSMUSP00000059210|uniprotkb:Q8BIU5|uniprotkb:Q505D8|uniprotkb:Q6PDK3|uniprotkb:Q5SUC2|uniprotkb:Q6ZQG5|uniprotkb:Q8R3T0|intact:MINT-8375705 intact:EBI-11707298|uniprotkb:G3X9I8|ensembl:ENSMUSP00000080832 psi-mi:maml1_mouse(display_long)|uniprotkb:Maml1(gene name)|psi-mi:Maml1(display_short)|uniprotkb:Kiaa0200(gene name synonym) psi-mi:hda10_mouse(display_long)|uniprotkb:Histone deacetylase 10(gene name synonym)|uniprotkb:Hdac10(gene name)|psi-mi:Hdac10(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670066|imex:IM-28774-3225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000050567(gene)|ensembl:ENSMUST00000059458(transcript)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0060928"(atrioventricular node cell development)|interpro:IPR019082|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0010831"(positive regulation of myotube differentiation)|refseq:NP_780543.2|entrezgene/locuslink:103806(identity) refseq:NP_954668.2|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|ensembl:ENSMUSG00000062906(gene)|ensembl:ENSMUST00000082197(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|entrezgene/locuslink:170787(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Us4w80GoyIJvEFn21oB6J1MqGHg10090 rogid:DahoUwe9Em+xnUFMmwG8mLiA4UY10090 rigid:jBB+2BIkIeVPrgPbJTwS4cvf5V4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VCG9 uniprotkb:Q61545 intact:EBI-26670044|ensembl:ENSMUSP00000040917|uniprotkb:Q91Y54 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rfxap_mouse(display_long)|uniprotkb:Rfxap(gene name)|psi-mi:Rfxap(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670058|imex:IM-28774-3223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036615(gene)|ensembl:ENSMUST00000044373(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR029316|interpro:IPR038308|refseq:NP_573494.1|entrezgene/locuslink:170767(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RP4CH6GaJjva/VIVKB8zV4VAEwE10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:mM0dTZaQpXDGsvjhwoxgPcMZVd8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VI67 uniprotkb:P43120 intact:EBI-7608836|intact:MINT-7709305|uniprotkb:Q8C5R3|uniprotkb:Q8C6A7|ensembl:ENSMUSP00000077596 intact:EBI-26669953|ensembl:ENSMUSP00000025944|uniprotkb:Q544N6|uniprotkb:Q9CRV1|uniprotkb:Q9R1X2 psi-mi:sp7_mouse(display_long)|uniprotkb:Sp7(gene name)|psi-mi:Sp7(display_short)|uniprotkb:Osx(gene name synonym)|uniprotkb:Zinc finger protein osterix(gene name synonym)|uniprotkb:C22(gene name synonym) psi-mi:hhex_mouse(display_long)|uniprotkb:Homeobox protein PRH(gene name synonym)|uniprotkb:Hhex(gene name)|psi-mi:Hhex(display_short)|uniprotkb:Prh(gene name synonym)|uniprotkb:Prhx(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670036|imex:IM-28774-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006520582.1|refseq:NP_569725.1|ensembl:ENSMUSG00000060284(gene)|ensembl:ENSMUST00000078508(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001335134.1|dip:DIP-46090N|entrezgene/locuslink:170574(identity) ensembl:ENSMUSG00000024986(gene)|ensembl:ENSMUST00000025944(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007492"(endoderm development)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0060431"(primary lung bud formation)|go:"GO:0061009"(common bile duct development)|go:"GO:0061010"(gall bladder development)|go:"GO:0061011"(hepatic duct development)|go:"GO:0061017"(hepatoblast differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070663"(regulation of leukocyte proliferation)|go:"GO:0071103"(DNA conformation change)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_032271.1|entrezgene/locuslink:15242(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K0m+DSmlpuLgh99ZP2r0wt328nk10090 rogid:CFFMI2L8Rr327CW687XQBaotsDQ10090 rigid:qGj1rza4uGY+8s6kpNAYfyomD7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:E9Q7L6 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-26670490|ensembl:ENSMUSP00000107857 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:e9q7l6_mouse(display_long)|uniprotkb:Foxn2(gene name)|psi-mi:Foxn2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670512|imex:IM-28774-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) ensembl:ENSMUSG00000034998(gene)|ensembl:ENSMUST00000112238(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_851305.2|refseq:XP_006523714.1|refseq:XP_006523715.1|refseq:XP_006523716.1|refseq:XP_006523717.1|entrezgene/locuslink:14236(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:0Q80fJTtlauGRomropH9xTNH9kA10090 rigid:V3fRZuLlbnYQfgK3Vi7hKuoBh0A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CCE9 uniprotkb:Q07279 intact:EBI-7450874|uniprotkb:Q6IR08|intact:MINT-4979074|uniprotkb:Q62065|uniprotkb:Q9QY56|uniprotkb:Q6PGI1|uniprotkb:Q3UNJ9|uniprotkb:Q05BH7 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:e4f1_mouse(display_long)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:Transcription factor phi AP3(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:E4f1(gene name)|psi-mi:E4f1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670482|imex:IM-28774-2803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011244570.1|refseq:NP_001288713.1|mint:Q8CCE9|interpro:IPR036236|refseq:NP_031919.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|entrezgene/locuslink:13560(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a0EPaeWXcFlLScLgeeeuixQ960Y10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:525w5Qm3sOTjUce20Q+hchNeeYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:P70396 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670474|imex:IM-28774-3229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rigid:bCRqKVuD6l2RLsO7N4rGpSCwg2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05BA5 uniprotkb:Q8CFN5 intact:EBI-5745783|ensembl:ENSMUSP00000085416 intact:EBI-643797|uniprotkb:Q8R0H1|uniprotkb:Q9D7L0|uniprotkb:Q9QW20|ensembl:ENSMUSP00000143212|ensembl:ENSMUSP00000143401 psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:mef2c_mouse(display_long)|uniprotkb:Myocyte enhancer factor 2C(gene name synonym)|uniprotkb:Mef2c(gene name)|psi-mi:Mef2c(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670343|imex:IM-28774-1035 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) refseq:NP_079558.1|ensembl:ENSMUSG00000005583(gene)|ensembl:ENSMUST00000199019(transcript)|ensembl:ENSMUST00000199105(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003185"(sinoatrial valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007611"(learning or memory)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048666"(neuron development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|rcsb pdb:5F28|reactome:R-MMU-525793|refseq:XP_006517186.1|refseq:XP_006517187.1|refseq:XP_006517189.1|refseq:XP_006517195.1|refseq:XP_011242794.1|refseq:XP_017170894.1|refseq:NP_001334504.1|refseq:NP_001334505.1|refseq:NP_001334506.1|refseq:NP_001334493.1|refseq:NP_001334495.1|refseq:NP_001334496.1|refseq:NP_001334497.1|refseq:NP_001334498.1|refseq:NP_001334500.1|refseq:NP_001334501.1|refseq:NP_001334502.1|refseq:NP_001334503.1|dip:DIP-49524N|entrezgene/locuslink:17260(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rogid:Wpir/aP9UI1pA7jZYsB2aMJWTrQ10090 rigid:DWIPtEuWxoclOTJ88YdQxin77Io false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:Q640N1 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-26670419|ensembl:ENSMUSP00000099987|uniprotkb:O88442|uniprotkb:Q3TVV5|uniprotkb:Q3TWA7|uniprotkb:Q3TX56|uniprotkb:Q3TXB2|uniprotkb:Q5NCI9|uniprotkb:Q61281 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:aebp1_mouse(display_long)|uniprotkb:Aortic carboxypeptidase-like protein(gene name synonym)|uniprotkb:Aebp1(gene name)|psi-mi:Aebp1(display_short)|uniprotkb:Aclp(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670458|imex:IM-28774-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) ensembl:ENSMUSG00000020473(gene)|ensembl:ENSMUST00000102923(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:1904026"(regulation of collagen fibril organization)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR008979(Galactose-binding like)|refseq:NP_001278786.1|refseq:NP_033766.2|entrezgene/locuslink:11568(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:QVnPQgzue6oKrevbBCdvlgr8dO010090 rigid:Oc0lj6ZCGYqJDPBQ7+szVcBMX7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70660 uniprotkb:Q61909 intact:EBI-26670359|ensembl:ENSMUSP00000050484 intact:EBI-309458|ensembl:ENSMUSP00000095856 psi-mi:ngn1_mouse(display_long)|uniprotkb:Helix-loop-helix protein mATH-4C(gene name synonym)|uniprotkb:Neurogenic basic-helix-loop-helix protein(gene name synonym)|uniprotkb:Neurogenic differentiation factor 3(gene name synonym)|uniprotkb:Neurog1(gene name)|psi-mi:Neurog1(display_short)|uniprotkb:Ath4c(gene name synonym)|uniprotkb:Neurod3(gene name synonym)|uniprotkb:Ngn(gene name synonym)|uniprotkb:Ngn1(gene name synonym) psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670411|imex:IM-28774-1943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048904(gene)|ensembl:ENSMUST00000058475(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032653|interpro:IPR036638|refseq:NP_035026.1|entrezgene/locuslink:18014(identity) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kk03Mhm9ylrkIAqyb4FhA0hjOQI10090 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rigid:wcIJT2LYD4g4QV+a2cKbNYbHrsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60867 uniprotkb:Q61909 intact:EBI-309315|uniprotkb:Q545N9|uniprotkb:Q60897|ensembl:ENSMUSP00000040364 intact:EBI-309458|ensembl:ENSMUSP00000095856 psi-mi:ndf1_mouse(display_long)|uniprotkb:Neurod1(gene name)|psi-mi:Neurod1(display_short)|uniprotkb:Neurod(gene name synonym)|uniprotkb:Beta-cell E-box transcriptional activator 2(gene name synonym) psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670351|imex:IM-28774-2801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035024.1|ensembl:ENSMUST00000041099(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|ensembl:ENSMUSG00000034701(gene)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR022575|interpro:IPR032652|go:"GO:0048562"(embryonic organ morphogenesis)|interpro:IPR036638|rcsb pdb:2QL2|go:"GO:0048666"(neuron development)|go:"GO:0048839"(inner ear development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060730"(regulation of intestinal epithelial structure maintenance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:18012(identity) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EOCuRlE8Dhx0NzTQi52B/NrEt0A10090 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rigid:dTflt4DfgZ1fY3QcgbQZQ2VqFI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:P79621 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670466|imex:IM-28774-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:FWjPJ0e6Y/OCoZeykeQlxwrfWOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:Q9DBA9 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-6260822|uniprotkb:O35637 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:tf2h1_mouse(display_long)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Gtf2h1(gene name)|psi-mi:Gtf2h1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670520|imex:IM-28774-3231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|refseq:NP_001278004.1|interpro:IPR035925|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|refseq:NP_032212.3|interpro:IPR027079|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|entrezgene/locuslink:14884(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:kCRvc9Bheu2o11ISottCk0cgERI10090 rigid:AxVO2FDPB1ybpa3XzLBe1hwtzbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:P49710 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-924601|uniprotkb:Q922I8|ensembl:ENSMUSP00000023531 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:hcls1_mouse(display_long)|uniprotkb:Hcls1(gene name)|psi-mi:Hcls1(display_short)|uniprotkb:Hs1(gene name synonym)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670528|imex:IM-28774-1037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) refseq:NP_032251.2|ensembl:ENSMUSG00000022831(gene)|ensembl:ENSMUST00000023531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P49710|entrezgene/locuslink:15163(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:f0+oPP9relryVZzce7RHfggQnGk10090 rigid:2iyu3XNyi3XlEI/Ff3IoGplg1HE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24610 uniprotkb:O35137 intact:EBI-1208116|uniprotkb:Q3UFQ9|uniprotkb:Q8BRE7|uniprotkb:Q9CXI6|ensembl:ENSMUSP00000084320 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:pax3_mouse(display_long)|uniprotkb:Pax3(gene name)|psi-mi:Pax3(display_short)|uniprotkb:Pax-3(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670891|imex:IM-28774-1511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152992.1|refseq:NP_032807.3|ensembl:ENSMUSG00000004872(gene)|ensembl:ENSMUST00000087086(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0007507"(heart development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0060594"(mammary gland specification)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P24610|reactome:R-MMU-3214847|go:"GO:0055007"(cardiac muscle cell differentiation)|entrezgene/locuslink:18505(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:medJ8P8C569COvZVEjQwWZCngdc10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:g85GfFUQuOcJBkw5QfDKHy5fL4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TPV4 uniprotkb:Q07279 intact:EBI-1373622|uniprotkb:O35851|uniprotkb:Q80Y66|uniprotkb:Q8R4X2|uniprotkb:Q99KP0|ensembl:ENSMUSP00000044827 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:mbb1a_mouse(display_long)|uniprotkb:Mybbp1a(gene name)|psi-mi:Mybbp1a(display_short)|uniprotkb:P160(gene name synonym)|uniprotkb:Myb-binding protein of 160 kDa(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670883|imex:IM-28774-2807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058056.2|dip:DIP-39831N|ensembl:ENSMUSG00000040463(gene)|ensembl:ENSMUST00000045633(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR016024(Armadillo-type fold)|mint:Q7TPV4|reactome:R-MMU-5250924|entrezgene/locuslink:18432(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rt1TQLZB7JNBkpt3DooDAlzOYCo10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:6z/clS8uR1dsX4k4CR/MLQbvLa4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0B5 uniprotkb:P70321 intact:EBI-26670824|ensembl:ENSMUSP00000112532 intact:EBI-925221|uniprotkb:Q80Y12|ensembl:ENSMUSP00000056315 psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:hxb13_mouse(display_long)|uniprotkb:Hoxb13(gene name)|psi-mi:Hoxb13(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670875|imex:IM-28774-1949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) refseq:NP_032293.1|ensembl:ENSMUSG00000049604(gene)|ensembl:ENSMUST00000062709(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:15408(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rogid:yjyTaVd+DMfgTpGB9PF4iYLjXzU10090 rigid:1MJ+3EPFvYnxnpYhsSCd5ytTC/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0B5 uniprotkb:Q04742 intact:EBI-26670824|ensembl:ENSMUSP00000112532 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670867|imex:IM-28774-2407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:R2EtNwAnB9mizUmYrHga1SRV6rk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0B5 uniprotkb:O35137 intact:EBI-26670824|ensembl:ENSMUSP00000112532 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670859|imex:IM-28774-1043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:p8WiZ5xPfU88R6HGsvwXua8SOps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0B5 uniprotkb:O35137 intact:EBI-26670824|ensembl:ENSMUSP00000112532 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670851|imex:IM-28774-1509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:p8WiZ5xPfU88R6HGsvwXua8SOps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60862 uniprotkb:Q07279 intact:EBI-457142|ensembl:ENSMUSP00000027198 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:orc2_mouse(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:Orc2l(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670816|imex:IM-28774-1507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032791.1|ensembl:ENSMUSG00000026037(gene)|ensembl:ENSMUST00000027198(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000808"(origin recognition complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005813"(centrosome)|go:"GO:0006260"(DNA replication)|interpro:IPR007220(Origin recognition complex subunit 2)|reactome:R-MMU-176187|reactome:R-MMU-68616|reactome:R-MMU-68689|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|refseq:NP_001258455.1|entrezgene/locuslink:18393(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mG5foO+hpAPT/3BIw9jDTSVR5p010090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:WwH6ZHM0sxzhPbG7kBGNXH4Rje8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54915 uniprotkb:Q05BA5 intact:EBI-11892436|ensembl:ENSMUSP00000023504 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:nr1i2_mouse(display_long)|uniprotkb:Nr1i2(gene name)|psi-mi:Nr1i2(display_short)|uniprotkb:Pxr(gene name synonym)|uniprotkb:Orphan nuclear receptor PXR(gene name synonym)|uniprotkb:Pregnane X receptor(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670808|imex:IM-28774-2405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091874.1|refseq:NP_035066.1|refseq:XP_006521909.1|refseq:XP_006521911.1|ensembl:ENSMUSG00000022809(gene)|ensembl:ENSMUST00000023504(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042738"|go:"GO:0042908"(xenobiotic transport)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|reactome:R-MMU-4090294|entrezgene/locuslink:18171(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:o7EexQngGpeyhpov78niLRiK/I410090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:gP7qKMY+T49ehWgfQXd0bLPmF6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QZB6 uniprotkb:Q07243 intact:EBI-26670677|ensembl:ENSMUSP00000030025|uniprotkb:Q9QZB5 intact:EBI-26670765|ensembl:ENSMUSP00000030723|ensembl:ENSMUSP00000101799|uniprotkb:Q9JJW8 psi-mi:nr4a3_mouse(display_long)|uniprotkb:Orphan nuclear receptor TEC(gene name synonym)|uniprotkb:Translocated in extraskeletal chondrosarcoma(gene name synonym)|uniprotkb:Nr4a3(gene name)|psi-mi:Nr4a3(display_short)|uniprotkb:Tec(gene name synonym) psi-mi:mtf1_mouse(display_long)|uniprotkb:MRE-binding transcription factor(gene name synonym)|uniprotkb:Transcription factor MTF-1(gene name synonym)|uniprotkb:Mtf1(gene name)|psi-mi:Mtf1(display_short)|uniprotkb:Mtf-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670800|imex:IM-28774-2403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028341(gene)|ensembl:ENSMUST00000030025(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007411"(axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009444"(pyruvate oxidation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030534"(adult behavior)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0038097"(positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045333"(cellular respiration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060005"(vestibular reflex)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000108"(positive regulation of leukocyte apoptotic process)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003072(Orphan nuclear receptor, NOR1 type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001294918.1|refseq:NP_056558.1|refseq:XP_006537719.1|refseq:XP_006537720.1|refseq:XP_006537721.1|entrezgene/locuslink:18124(identity) ensembl:ENSMUSG00000028890(gene)|ensembl:ENSMUST00000030723(transcript)|ensembl:ENSMUST00000106193(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:1990079"(cartilage homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029796|interpro:IPR036236|refseq:NP_032662.3|entrezgene/locuslink:17764(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hvk9nzkP+G3jLluo4cGSjr+j5Cs10090 rogid:3a3aJs0bsRGzr9qHPcpSo5BxmBQ10090 rigid:NR724ZTYi/9nH2P5cs8lSC5Xe3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QZB6 uniprotkb:Q61827 intact:EBI-26670677|ensembl:ENSMUSP00000030025|uniprotkb:Q9QZB5 intact:EBI-15740843|ensembl:ENSMUSP00000018287|ensembl:ENSMUSP00000106460|uniprotkb:Q60600 psi-mi:nr4a3_mouse(display_long)|uniprotkb:Orphan nuclear receptor TEC(gene name synonym)|uniprotkb:Translocated in extraskeletal chondrosarcoma(gene name synonym)|uniprotkb:Nr4a3(gene name)|psi-mi:Nr4a3(display_short)|uniprotkb:Tec(gene name synonym) psi-mi:mafk_mouse(display_long)|uniprotkb:Mafk(gene name)|psi-mi:Mafk(display_short)|uniprotkb:Nfe2u(gene name synonym)|uniprotkb:Erythroid transcription factor NF-E2 p18 subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670757|imex:IM-28774-3237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028341(gene)|ensembl:ENSMUST00000030025(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007411"(axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009444"(pyruvate oxidation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030534"(adult behavior)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0038097"(positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045333"(cellular respiration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060005"(vestibular reflex)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000108"(positive regulation of leukocyte apoptotic process)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003072(Orphan nuclear receptor, NOR1 type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001294918.1|refseq:NP_056558.1|refseq:XP_006537719.1|refseq:XP_006537720.1|refseq:XP_006537721.1|entrezgene/locuslink:18124(identity) ensembl:ENSMUSG00000018143(gene)|ensembl:ENSMUST00000018287(transcript)|ensembl:ENSMUST00000110836(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR028574|reactome:R-MMU-9707616|reactome:R-MMU-9708530|reactome:R-MMU-983231|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_034887.1|refseq:XP_006504716.1|dip:DIP-46345N|entrezgene/locuslink:17135(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hvk9nzkP+G3jLluo4cGSjr+j5Cs10090 rogid:zGCUuA/T7af0ZTc1fmzBIio6iec10090 rigid:Ic3JdwTVDW2sNeLMAUpL5Js0udE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03966 uniprotkb:P28574 intact:EBI-647752|uniprotkb:Q61978|ensembl:ENSMUSP00000045993|ensembl:ENSMUSP00000114225 intact:EBI-1183003|ensembl:ENSMUSP00000106025|uniprotkb:B2RS19|uniprotkb:Q8C4Y1|intact:EBI-11108903 psi-mi:mycn_mouse(display_long)|uniprotkb:Mycn(gene name)|psi-mi:Mycn(display_short)|uniprotkb:Nmyc(gene name synonym)|uniprotkb:Nmyc1(gene name synonym) psi-mi:max_mouse(display_long)|uniprotkb:Myc-associated factor X(gene name synonym)|uniprotkb:Protein myn(gene name synonym)|uniprotkb:Myc-binding novel HLH/LZ protein(gene name synonym)|uniprotkb:Max(gene name)|psi-mi:Max(display_short)|uniprotkb:Myn(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670669|imex:IM-28774-1947 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032735.3|dip:DIP-49592N|ensembl:ENSMUSG00000037169(gene)|ensembl:ENSMUST00000043396(transcript)|ensembl:ENSMUST00000130990(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019900"(kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|entrezgene/locuslink:18109(identity) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P28574|rcsb pdb:1A93|rcsb pdb:2A93|rcsb pdb:3U5V|reactome:R-MMU-8953750|go:"GO:0071339"(MLL1 complex)|ensembl:ENSMUSG00000059436(gene)|ensembl:ENSMUST00000110395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001139648.1|refseq:NP_032584.2|dip:DIP-116N|entrezgene/locuslink:17187(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:J+RjU57FyHczGnzHYpNaUKOiw6k10090 rogid:/kXjf+gpJ5uqNX3tZ6WD+ZwtxJY10090 rigid:mNIPsALVIsdWb9xOLhGWauoDDzw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97334 uniprotkb:P18111 intact:EBI-26670620|ensembl:ENSMUSP00000050933|uniprotkb:Q9QZ60|uniprotkb:Q9WV67 intact:EBI-21005290|ensembl:ENSMUSP00000025521|uniprotkb:Q8VCF7 psi-mi:nkx23_mouse(display_long)|uniprotkb:Homeobox protein NK-2 homolog 3(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog C(gene name synonym)|uniprotkb:Nkx2-C(gene name synonym)|uniprotkb:Nkx2-3(gene name)|psi-mi:Nkx2-3(display_short)|uniprotkb:Nkx-2.3(gene name synonym)|uniprotkb:Nkx2c(gene name synonym) psi-mi:cdx1_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 1(gene name synonym)|uniprotkb:Cdx1(gene name)|psi-mi:Cdx1(display_short)|uniprotkb:Cdx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670661|imex:IM-28774-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000044220(gene)|ensembl:ENSMUST00000057178(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048565"(digestive tract development)|go:"GO:0048621"(post-embryonic digestive tract morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0022612"(gland morphogenesis)|refseq:NP_032725.1|entrezgene/locuslink:18089(identity) go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060349"(bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000024619(gene)|ensembl:ENSMUST00000025521(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|refseq:NP_034010.3|entrezgene/locuslink:12590(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bLGV6jFbwIJSrV3mhxasbc8RPBc10090 rogid:Rzc2qIxNozTifZX/rvuUx8uc6lU10090 rigid:eAONBu+Ex1hD4i6nkgx+7zjtYCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTK5 uniprotkb:P25799 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670612|imex:IM-28774-1041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6|entrezgene/locuslink:18034(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:hnp+FbjNC+d+C0qeof7g3dBkTB8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTK5 uniprotkb:P25799 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670604|imex:IM-28774-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6|entrezgene/locuslink:18034(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:hnp+FbjNC+d+C0qeof7g3dBkTB8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25799 uniprotkb:Q8C5D8 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 intact:EBI-6305825|ensembl:ENSMUSP00000110425|uniprotkb:O54987|uniprotkb:Q8C384|uniprotkb:Q8CDQ8|uniprotkb:Q8K208|uniprotkb:Q99JX5|uniprotkb:Q9D5W7|uniprotkb:Q9QZ63 psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:pias2_mouse(display_long)|uniprotkb:Pias2(gene name)|psi-mi:Pias2(display_short)|uniprotkb:Miz1(gene name synonym)|uniprotkb:Piasx(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670596|imex:IM-28774-3235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) ensembl:ENSMUSG00000025423(gene)|ensembl:ENSMUST00000114777(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|interpro:IPR023321|refseq:NP_001157639.1|refseq:NP_001157640.1|refseq:NP_001157641.1|refseq:NP_001157642.1|refseq:NP_032628.3|entrezgene/locuslink:17344(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rogid:cdbtERVlS8Tq/izExMTjb0x27P010090 rigid:0QWhuL3tFH0pcQ1W1Fif+I6frfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54790 uniprotkb:Q60795 intact:EBI-8339457|intact:MINT-4101043|ensembl:ENSMUSP00000053899|ensembl:ENSMUSP00000101786|ensembl:ENSMUSP00000101787|ensembl:ENSMUSP00000101788 intact:EBI-642563|uniprotkb:Q3UQK0|ensembl:ENSMUSP00000099733 psi-mi:mafg_mouse(display_long)|uniprotkb:Mafg(gene name)|psi-mi:Mafg(display_short)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog G(gene name synonym) psi-mi:nf2l2_mouse(display_long)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)|uniprotkb:Nfe2l2(gene name)|psi-mi:Nfe2l2(display_short)|uniprotkb:Nrf2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670588|imex:IM-28774-3233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034886.1|refseq:XP_017169797.1|refseq:XP_017169798.1|refseq:XP_017169799.1|refseq:XP_017169800.1|dip:DIP-46344N|ensembl:ENSMUSG00000051510(gene)|ensembl:ENSMUST00000058162(transcript)|ensembl:ENSMUST00000106180(transcript)|ensembl:ENSMUST00000106181(transcript)|ensembl:ENSMUST00000106182(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030534"(adult behavior)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR028551|mint:O54790|rcsb pdb:1K1V|rcsb pdb:3A5T|reactome:R-MMU-983231|entrezgene/locuslink:17134(identity) refseq:NP_035032.1|ensembl:ENSMUSG00000015839(gene)|ensembl:ENSMUST00000102672(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035690"|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046223"(aflatoxin catabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029845|rcsb pdb:1X2R|rcsb pdb:2DYH|rcsb pdb:3WN7|reactome:R-MMU-8932339|dip:DIP-49666N|entrezgene/locuslink:18024(identity) - comment:mint|function:"Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Czx9HKnnVMTJudPKQ9JEJtUo+c810090 rogid:flFH5+oCBXzNgfBzUiwuHtDQla810090 rigid:kNnQILPjxrA0o21W/wsDo6xtEeA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:O88522 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670580|imex:IM-28774-1505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:PzzhQgxM0IH3ilsACaCGwzVS2sg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:P10284 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-925414|uniprotkb:Q3UZB4|uniprotkb:Q4VBG0|ensembl:ENSMUSP00000048002 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:hxb4_mouse(display_long)|uniprotkb:Hoxb4(gene name)|psi-mi:Hoxb4(display_short)|uniprotkb:Hox-2.6(gene name synonym)|uniprotkb:Hoxb-4(gene name synonym)|uniprotkb:Homeobox protein Hox-2.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670572|imex:IM-28774-2805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) refseq:NP_034589.3|ensembl:ENSMUSG00000038692(gene)|ensembl:ENSMUST00000049241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030097"(hemopoiesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048536"(spleen development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|entrezgene/locuslink:15412(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:k9Xu6L/qLD3dnSR0u2ZBXfskTAg10090 rigid:YxosRQ3f04hOSV+huSoS7dyStoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07279 uniprotkb:P06798 intact:EBI-6554737|uniprotkb:Q6P6K5 intact:EBI-26670536|uniprotkb:Q61684|uniprotkb:Q64388|uniprotkb:Q8BPE6 psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:hxa4_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.4(gene name synonym)|uniprotkb:Homeobox protein MH-3(gene name synonym)|uniprotkb:Hoxa4(gene name)|psi-mi:Hoxa4(display_short)|uniprotkb:Hox-1.4(gene name synonym)|uniprotkb:Hoxa-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670564|imex:IM-28774-1945 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_032291.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR017995|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR020479|entrezgene/locuslink:15401(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rogid:L4ixAWZ70QDil6IfikULduqjgF810090 rigid:0HyV7Ef46EUVsIN6MJRbqod6IXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63015 uniprotkb:P09631 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670899|imex:IM-28774-1045 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like)|entrezgene/locuslink:18508(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:2zfP1Ln8ZXN8cwA8IJ9BYs2xN+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:B9EHK7 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26670915|ensembl:ENSMUSP00000000964 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:b9ehk7_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670939|imex:IM-28774-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000029844(gene)|ensembl:ENSMUST00000000964(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034579.3|refseq:XP_006505670.1|entrezgene/locuslink:15394(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:LqWHYSQkWiAjpRFKLxRNNiC49DA10090 rigid:orzxYsS7uj3aY7p+F7dWt7n3Xug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63015 uniprotkb:Q8K5B8 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670907|imex:IM-28774-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like)|entrezgene/locuslink:18508(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:J96xxJdEkF1a/aB3mSjCKwmvDNE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P97367 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671124|imex:IM-28774-2811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:JmmcavgOc4bD9v5862rhR8MsueI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P97367 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671116|imex:IM-28774-1957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:JmmcavgOc4bD9v5862rhR8MsueI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q60954 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671108|imex:IM-28774-1515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:uE4Y7o8tfByxq/hiVK5ah8pVuR0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q60954 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671100|imex:IM-28774-3239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:uE4Y7o8tfByxq/hiVK5ah8pVuR0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P10628 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26671059|ensembl:ENSMUSP00000047949|ensembl:ENSMUSP00000107611|uniprotkb:A2ASN3|uniprotkb:P97451|uniprotkb:Q3UXL6 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxd4_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.2(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym)|uniprotkb:Hoxd4(gene name)|psi-mi:Hoxd4(display_short)|uniprotkb:Hox-4.2(gene name synonym)|uniprotkb:Hoxd-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671092|imex:IM-28774-1513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUST00000047904(transcript)|ensembl:ENSMUST00000111980(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|ensembl:ENSMUSG00000101174(gene)|refseq:NP_034599.2|entrezgene/locuslink:15436(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:ZxWKuuDpzZjmGsfihJsfPo0M42Q10090 rigid:m7wFRbNYA2Rmt1wrvWyVP1kPYss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P28359 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-445929|uniprotkb:Q91WU9|ensembl:ENSMUSP00000062412 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxd10_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.5(gene name synonym)|uniprotkb:Hoxd10(gene name)|psi-mi:Hoxd10(display_short)|uniprotkb:Hox-4.5(gene name synonym)|uniprotkb:Hoxd-10(gene name synonym)|uniprotkb:Homeobox protein Hox-5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671051|imex:IM-28774-2809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_038582.2|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050905"(neuromuscular process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000050368(gene)|ensembl:ENSMUST00000061745(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:15430(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:N3cD2IcsB+0/7fer4wg5hZBLuew10090 rigid:bMq9ov91gUio8LI4C6Fo9YuoGho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P32043 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26671019|ensembl:ENSMUSP00000001709|uniprotkb:Q8BJW4 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxc5_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.4(gene name synonym)|uniprotkb:Homeobox protein Hox-6.2(gene name synonym)|uniprotkb:Hoxc5(gene name)|psi-mi:Hoxc5(display_short)|uniprotkb:Hox-3.4(gene name synonym)|uniprotkb:Hoxc-5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671043|imex:IM-28774-1053 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000022485(gene)|ensembl:ENSMUST00000001709(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_783857.1|entrezgene/locuslink:15424(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:4uFRMqqb32OVMPfabQFEoqe9KFk10090 rigid:/HJ2ew8bMLnGaLa6lsj0HRRACIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q08624 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26668976|ensembl:ENSMUSP00000097740 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671011|imex:IM-28774-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rigid:CMLTMZFFkNTUcVvft3Tqi0a9+W8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q08624 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26668976|ensembl:ENSMUSP00000097740 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671003|imex:IM-28774-2411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rigid:CMLTMZFFkNTUcVvft3Tqi0a9+W8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q8K5B8 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670995|imex:IM-28774-1955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:FAhYYQuJ/hCsSL55Y1FdDnlq/0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P09632 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670987|imex:IM-28774-1953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:ZEp2RmjuSxdtHsY2O5Zpx6xC7kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P09023 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-15992861|ensembl:ENSMUSP00000000704|ensembl:ENSMUSP00000133281 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxb6_mouse(display_long)|uniprotkb:Hoxb6(gene name)|psi-mi:Hoxb6(display_short)|uniprotkb:Hox-2.2(gene name synonym)|uniprotkb:Hoxb-6(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein MH-22A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670979|imex:IM-28774-1051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000000690(gene)|ensembl:ENSMUST00000000704(transcript)|ensembl:ENSMUST00000173432(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_032295.1|dip:DIP-59870N|entrezgene/locuslink:15414(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:yLbga2gC2JdNQr6AIx3K736hL7o10090 rigid:UZbRAv6c5DxYVwbVT8BwwT4ykm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P09631 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670971|imex:IM-28774-1951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:FcU1+cA7LqjZ/kE9f54pbDOm+VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P09092 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26668838|ensembl:ENSMUSP00000058755|uniprotkb:Q9JI98 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxa6_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.2(gene name synonym)|uniprotkb:Homeobox protein M5-4(gene name synonym)|uniprotkb:Hoxa6(gene name)|psi-mi:Hoxa6(display_short)|uniprotkb:Hox-1.2(gene name synonym)|uniprotkb:Hoxa-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670963|imex:IM-28774-1049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000043219(gene)|ensembl:ENSMUST00000062829(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_034584.1|entrezgene/locuslink:15403(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:h4344WEVFSGp7m6UWPSAQn7hIVU10090 rigid:hlme3PCEF6le86GqYdtJTXqxeTw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P09021 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-925394|uniprotkb:Q91VQ5|ensembl:ENSMUSP00000039012 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxa5_mouse(display_long)|uniprotkb:Hoxa5(gene name)|psi-mi:Hoxa5(display_short)|uniprotkb:Hox-1.3(gene name synonym)|uniprotkb:Hoxa-5(gene name synonym)|uniprotkb:Homeobox protein Hox-1.3(gene name synonym)|uniprotkb:Homeobox protein M2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670955|imex:IM-28774-1047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_034583.1|ensembl:ENSMUSG00000038253(gene)|ensembl:ENSMUST00000048794(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060481"(lobar bronchus epithelium development)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P09021|entrezgene/locuslink:15402(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:1/djC9dlDssHzy1+X3zilRD+NPs10090 rigid:4pyOVLNph2vxIIJYxqeLwE2F1ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:P31310 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-446033|uniprotkb:Q80Y22|ensembl:ENSMUSP00000120276 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:hxa10_mouse(display_long)|uniprotkb:Hoxa10(gene name)|psi-mi:Hoxa10(display_short)|uniprotkb:Hox-1.8(gene name synonym)|uniprotkb:Hoxa-10(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670947|imex:IM-28774-2409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_001116422.1|refseq:NP_032289.2|ensembl:ENSMUSG00000000938(gene)|ensembl:ENSMUST00000125581(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0010468"(regulation of gene expression)|entrezgene/locuslink:15395(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:vWwVapO3YyVd8TG6MbGvBHZHOMo10090 rigid:j13jUL+XR6pJQY5GSmEKXE3Zxs0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47242 uniprotkb:B9EHK7 intact:EBI-3865062|ensembl:ENSMUSP00000001538|ensembl:ENSMUSP00000117928 intact:EBI-26670915|ensembl:ENSMUSP00000000964 psi-mi:pax9_mouse(display_long)|uniprotkb:Pax9(gene name)|psi-mi:Pax9(display_short)|uniprotkb:Pax-9(gene name synonym) psi-mi:b9ehk7_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26670931|imex:IM-28774-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035171.1|refseq:XP_006515642.1|refseq:XP_006515643.1|refseq:XP_006515644.1|ensembl:ENSMUSG00000001497(gene)|ensembl:ENSMUST00000001538(transcript)|ensembl:ENSMUST00000153250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042481"(regulation of odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|refseq:XP_017170480.1|entrezgene/locuslink:18511(identity) ensembl:ENSMUSG00000029844(gene)|ensembl:ENSMUST00000000964(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034579.3|refseq:XP_006505670.1|entrezgene/locuslink:15394(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9DTnU8hPiIIyHwJfWxR0pQBwqSA10090 rogid:LqWHYSQkWiAjpRFKLxRNNiC49DA10090 rigid:oMz/zyEq0LngpwWWbbfgiT4d1qQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:P31310 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-446033|uniprotkb:Q80Y22|ensembl:ENSMUSP00000120276 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:hxa10_mouse(display_long)|uniprotkb:Hoxa10(gene name)|psi-mi:Hoxa10(display_short)|uniprotkb:Hox-1.8(gene name synonym)|uniprotkb:Hoxa-10(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671132|imex:IM-28774-1959 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) refseq:NP_001116422.1|refseq:NP_032289.2|ensembl:ENSMUSG00000000938(gene)|ensembl:ENSMUST00000125581(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0010468"(regulation of gene expression)|entrezgene/locuslink:15395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:vWwVapO3YyVd8TG6MbGvBHZHOMo10090 rigid:LNm9DmT69JN/2dfDNzXTPaAq0KA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:P28359 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-445929|uniprotkb:Q91WU9|ensembl:ENSMUSP00000062412 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:hxd10_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.5(gene name synonym)|uniprotkb:Hoxd10(gene name)|psi-mi:Hoxd10(display_short)|uniprotkb:Hox-4.5(gene name synonym)|uniprotkb:Hoxd-10(gene name synonym)|uniprotkb:Homeobox protein Hox-5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671149|imex:IM-28774-1039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) refseq:NP_038582.2|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050905"(neuromuscular process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000050368(gene)|ensembl:ENSMUST00000061745(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:15430(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:N3cD2IcsB+0/7fer4wg5hZBLuew10090 rigid:67vzxitz0iTiVpz3ZY9Si2FS3UQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:Q8K5B8 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671141|imex:IM-28774-1961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:CmD6AU+9XQpokUV9eaVheISEkKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35973 uniprotkb:Q07279 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671468|imex:IM-28774-2415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:/+meub8tHLADDBHIVkG+gesRKnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35973 uniprotkb:Q05BA5 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671460|imex:IM-28774-3243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:DYFNNWVmRfcvc9efRVudsMCQp0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35973 uniprotkb:Q61545 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671452|imex:IM-28774-1059 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:+jgLZjvnkTgAgGXcTAYPS8EXp9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JHD1 uniprotkb:Q07279 intact:EBI-2325611|uniprotkb:Q3U142|uniprotkb:Q640M9|ensembl:ENSMUSP00000000724 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:kat2b_mouse(display_long)|uniprotkb:Pcaf(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:Kat2b(gene name)|psi-mi:Kat2b(display_short)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671444|imex:IM-28774-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064389.2|dip:DIP-29281N|ensembl:ENSMUSG00000000708(gene)|ensembl:ENSMUST00000000724(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042311"(vasodilation)|go:"GO:0042641"(actomyosin)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:2000233"(negative regulation of rRNA processing)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q9JHD1|rcsb pdb:5ML0|reactome:R-MMU-2032785|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-5250924|reactome:R-MMU-5689901|reactome:R-MMU-8936459|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-9617629|entrezgene/locuslink:18519(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - caution:This sequence has been withdrawn from Uniprot. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xnaxRvvz5/uqJD0Zt6tnXNQJ43g10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:EtjV+BRcLzB4uvAtroIz1AFd7yI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P97367 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671436|imex:IM-28774-1967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:27EaEQqEAatdJ3eWFmRE5AMQ4E8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:Q60954 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671428|imex:IM-28774-2815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:LdlXUKKs3LeMy/LcZ3G/RpiAdv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:Q60954 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671420|imex:IM-28774-1965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:LdlXUKKs3LeMy/LcZ3G/RpiAdv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P28357 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26671369|ensembl:ENSMUSP00000058490|uniprotkb:A2ASM9|uniprotkb:Q3UMQ3|uniprotkb:Q3UYS2 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxd9_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.4(gene name synonym)|uniprotkb:Homeobox protein Hox-5.2(gene name synonym)|uniprotkb:Hoxd9(gene name)|psi-mi:Hoxd9(display_short)|uniprotkb:Hox-4.4(gene name synonym)|uniprotkb:Hoxd-9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671412|imex:IM-28774-1519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000043342(gene)|ensembl:ENSMUST00000059272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_038583.1|entrezgene/locuslink:15438(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:yAO/qVdMO1kp4tqqEXeQlloLpOU10090 rigid:8ifGtf8/PAMMfjZ9ojSJY0YE5i8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P10628 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26671059|ensembl:ENSMUSP00000047949|ensembl:ENSMUSP00000107611|uniprotkb:A2ASN3|uniprotkb:P97451|uniprotkb:Q3UXL6 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxd4_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.2(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym)|uniprotkb:Hoxd4(gene name)|psi-mi:Hoxd4(display_short)|uniprotkb:Hox-4.2(gene name synonym)|uniprotkb:Hoxd-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671361|imex:IM-28774-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUST00000047904(transcript)|ensembl:ENSMUST00000111980(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|ensembl:ENSMUSG00000101174(gene)|refseq:NP_034599.2|entrezgene/locuslink:15436(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:ZxWKuuDpzZjmGsfihJsfPo0M42Q10090 rigid:VjaLDQhLkGwLaKza8oSpSsKcJOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P28359 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-445929|uniprotkb:Q91WU9|ensembl:ENSMUSP00000062412 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxd10_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.5(gene name synonym)|uniprotkb:Hoxd10(gene name)|psi-mi:Hoxd10(display_short)|uniprotkb:Hox-4.5(gene name synonym)|uniprotkb:Hoxd-10(gene name synonym)|uniprotkb:Homeobox protein Hox-5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671353|imex:IM-28774-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) refseq:NP_038582.2|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050905"(neuromuscular process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000050368(gene)|ensembl:ENSMUST00000061745(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:15430(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:N3cD2IcsB+0/7fer4wg5hZBLuew10090 rigid:9CgA8URxuPCAufz8qCC7N92UxYc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P10629 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26671321|ensembl:ENSMUSP00000001711|uniprotkb:Q61683 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxc6_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.3(gene name synonym)|uniprotkb:Homeobox protein Hox-6.1(gene name synonym)|uniprotkb:Hoxc6(gene name)|psi-mi:Hoxc6(display_short)|uniprotkb:Hox-3.3(gene name synonym)|uniprotkb:Hoxc-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671345|imex:IM-28774-2413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000001661(gene)|ensembl:ENSMUST00000001711(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034595.2|refseq:XP_006520532.1|entrezgene/locuslink:15425(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:uMymV17aUMMHjrOY+Fk8rArpOGs10090 rigid:Bp/o6xaczEBAJTewWvqDp5F87wI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P32043 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26671019|ensembl:ENSMUSP00000001709|uniprotkb:Q8BJW4 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxc5_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.4(gene name synonym)|uniprotkb:Homeobox protein Hox-6.2(gene name synonym)|uniprotkb:Hoxc5(gene name)|psi-mi:Hoxc5(display_short)|uniprotkb:Hox-3.4(gene name synonym)|uniprotkb:Hoxc-5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671313|imex:IM-28774-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000022485(gene)|ensembl:ENSMUST00000001709(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_783857.1|entrezgene/locuslink:15424(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:4uFRMqqb32OVMPfabQFEoqe9KFk10090 rigid:1BqyRJp3vin+Jt8LWmSwmYC6VEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:Q08624 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26668976|ensembl:ENSMUSP00000097740 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671305|imex:IM-28774-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rigid:aTr8uRaDptPzGNIFSGwxLRYVQW0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:Q8K5B8 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671297|imex:IM-28774-1963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:BIyWpxIKQrXJ4oLAQwMCyc9mt7o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P09632 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671289|imex:IM-28774-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:qFz1anvCODgoOBK0vj7ipVTsjXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P09079 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26671239|ensembl:ENSMUSP00000035423|uniprotkb:Q3ZAY8 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxb5_mouse(display_long)|uniprotkb:Homeobox protein H24.1(gene name synonym)|uniprotkb:Homeobox protein Hox-2.1(gene name synonym)|uniprotkb:Homeobox protein Mu-1(gene name synonym)|uniprotkb:Hoxb5(gene name)|psi-mi:Hoxb5(display_short)|uniprotkb:Hox-2.1(gene name synonym)|uniprotkb:Hoxb-5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671272|imex:IM-28774-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000038700(gene)|ensembl:ENSMUST00000049272(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017995|interpro:IPR020479|interpro:IPR017970|refseq:NP_032294.2|entrezgene/locuslink:15413(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:s8SXxXXrPmirctRlLvsBnwGqa/w10090 rigid:hpK1krsYm3DfnRX8cL6UklJNZe8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P09631 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671231|imex:IM-28774-1057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:yf5zw0jgAU/5fEWGUD2YCpFUY7Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35317 uniprotkb:P09092 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26668838|ensembl:ENSMUSP00000058755|uniprotkb:Q9JI98 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxa6_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.2(gene name synonym)|uniprotkb:Homeobox protein M5-4(gene name synonym)|uniprotkb:Hoxa6(gene name)|psi-mi:Hoxa6(display_short)|uniprotkb:Hox-1.2(gene name synonym)|uniprotkb:Hoxa-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671223|imex:IM-28774-1055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000043219(gene)|ensembl:ENSMUST00000062829(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_034584.1|entrezgene/locuslink:15403(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:h4344WEVFSGp7m6UWPSAQn7hIVU10090 rigid:LXsVUyBoGCWtKFXmA+g2VcuBsGk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:P97367 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671181|imex:IM-28774-3241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:yjrfC9+mghAD0qUmxR350+z6Rfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:P97367 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671173|imex:IM-28774-2813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:yjrfC9+mghAD0qUmxR350+z6Rfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:Q60954 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671165|imex:IM-28774-1517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:MPiaC5vQgzNevjzNVSmWz4PhgR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35984 uniprotkb:Q60954 intact:EBI-1373614|ensembl:ENSMUSP00000040464 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671157|imex:IM-28774-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:MPiaC5vQgzNevjzNVSmWz4PhgR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35973 uniprotkb:O35973 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671476|imex:IM-28774-1061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rigid:mt+rVZOUPOdX8XRl/WFCa5OaDPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q63934 uniprotkb:O35137 intact:EBI-26671769|ensembl:ENSMUSP00000034115|uniprotkb:Q63954 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:po4f2_mouse(display_long)|uniprotkb:Brain-specific homeobox/POU domain protein 3B(gene name synonym)|uniprotkb:Pou4f2(gene name)|psi-mi:Pou4f2(display_short)|uniprotkb:Brn-3.2(gene name synonym)|uniprotkb:Brn3b(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671838|imex:IM-28774-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031688(gene)|ensembl:ENSMUST00000034115(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048675"(axon extension)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090259"(regulation of retinal ganglion cell axon guidance)|go:"GO:1902870"(negative regulation of amacrine cell differentiation)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6804759|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|refseq:NP_620394.2|entrezgene/locuslink:18997(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v7ZfH8cB4fqZSxUz060RJHwoTtM10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:QHjz54XL/BnsTXf6a5dnDZOrkuA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54943 uniprotkb:O54943 intact:EBI-1266779|uniprotkb:O54954 intact:EBI-1266779|uniprotkb:O54954 psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671508|imex:IM-28774-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rigid:wSaRZ4zlIZE1Wk20+gTtTPGf9Sc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25425 uniprotkb:P25425 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671709|imex:IM-28774-3249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rigid:6sFim2O+Um+JS1hee8RxKFQOzD8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25425 uniprotkb:Q61179 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 intact:EBI-646653|ensembl:ENSMUSP00000120359 psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671701|imex:IM-28774-2417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rigid:q3vKX6wI2DtnhSviOv08mPStpfo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25425 uniprotkb:Q08624 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 intact:EBI-26668976|ensembl:ENSMUSP00000097740 psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671693|imex:IM-28774-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rigid:ohUHpp6K1GvTily7pMS+3+hVuPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25425 uniprotkb:P09632 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671685|imex:IM-28774-2821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:tXAY+MBuPe5O0sig1Xi42zoiBIg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25425 uniprotkb:P09631 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671677|imex:IM-28774-2819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:ae3PE/NVQL0goUJofqc4Mezb82c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25425 uniprotkb:P09092 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 intact:EBI-26668838|ensembl:ENSMUSP00000058755|uniprotkb:Q9JI98 psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:hxa6_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.2(gene name synonym)|uniprotkb:Homeobox protein M5-4(gene name synonym)|uniprotkb:Hoxa6(gene name)|psi-mi:Hoxa6(display_short)|uniprotkb:Hox-1.2(gene name synonym)|uniprotkb:Hoxa-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671669|imex:IM-28774-3247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) ensembl:ENSMUSG00000043219(gene)|ensembl:ENSMUST00000062829(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_034584.1|entrezgene/locuslink:15403(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rogid:h4344WEVFSGp7m6UWPSAQn7hIVU10090 rigid:VfZuJ4zoRER45xgYRa+syGlD3TQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60809 uniprotkb:Q04211 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-7847081|ensembl:ENSMUSP00000020692|intact:MINT-1517995 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:btg2_mouse(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Tis21(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible protein TIS21(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671661|imex:IM-28774-3245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115|entrezgene/locuslink:18983(identity) ensembl:ENSMUSG00000020423(gene)|ensembl:ENSMUST00000020692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|mint:Q04211|rcsb pdb:3DJN|go:"GO:0017148"(negative regulation of translation)|reactome:R-MMU-6804115|refseq:NP_031596.1|dip:DIP-41601N|entrezgene/locuslink:12227(identity) - - comment:mint|function:Anti-proliferative protein. Modulates transcription regulation mediated by ESR1 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:7BocM19zCEv3H2oW41XX6DMgaTY10090 rigid:rzVHNHSPzgDtLT6xOTOx4uaZG0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60809 uniprotkb:P62325 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-26671626|ensembl:ENSMUSP00000038863|uniprotkb:P31607 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:btg1_mouse(display_long)|uniprotkb:B-cell translocation gene 1 protein(gene name synonym)|uniprotkb:Btg1(gene name)|psi-mi:Btg1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671653|imex:IM-28774-1069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115|entrezgene/locuslink:18983(identity) ensembl:ENSMUSG00000036478(gene)|ensembl:ENSMUST00000038377(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033330|interpro:IPR033332|interpro:IPR036054|refseq:NP_031595.1|entrezgene/locuslink:12226(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:+XRny4AEbQHi+qxKV1Qsf9bOFG010090 rigid:vILQyKWojTAdwvy33jZ47y7vT8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63013 uniprotkb:O35137 intact:EBI-1208371|uniprotkb:P43271|uniprotkb:Q02810|uniprotkb:Q569N6|ensembl:ENSMUSP00000027878 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:prrx1_mouse(display_long)|uniprotkb:Prrx1(gene name)|psi-mi:Prrx1(display_short)|uniprotkb:Pmx(gene name synonym)|uniprotkb:Pmx1(gene name synonym)|uniprotkb:Paired-related homeobox protein 1(gene name synonym)|uniprotkb:Homeobox protein mHox(gene name synonym)|uniprotkb:Homeobox protein K-2(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671618|imex:IM-28774-2817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035257.1|refseq:NP_783617.2|refseq:XP_006496766.1|go:"GO:0048664"(neuron fate determination)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070570"(regulation of neuron projection regeneration)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR043378|ensembl:ENSMUSG00000026586(gene)|ensembl:ENSMUST00000027878(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|entrezgene/locuslink:18933(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:simWBWVD8ayKawmbzE/Usq3px3c10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:QlWnNOle4xko9Zk2lBELYo65ZrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60953 uniprotkb:Q60953 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671602|imex:IM-28774-1067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:mf6Di1N/oHBY6AnbzxvHi48UH8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70477 uniprotkb:O35317 intact:EBI-26671524|ensembl:ENSMUSP00000094966|ensembl:ENSMUSP00000134852|ensembl:ENSMUSP00000135804|uniprotkb:Q7TT01 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 psi-mi:pknx1_mouse(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Prep1(gene name synonym)|uniprotkb:Pknox1(gene name)|psi-mi:Pknox1(display_short) psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671594|imex:IM-28774-1065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006705(gene)|ensembl:ENSMUST00000097352(transcript)|ensembl:ENSMUST00000175806(transcript)|ensembl:ENSMUST00000176701(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:NP_057879.2|refseq:XP_006523917.1|refseq:XP_006523918.1|entrezgene/locuslink:18771(identity) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xm0jPdkFFT+13skBNDcjknXhBEo10090 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rigid:1zGZJkfu++tQY2OQYDUR/Zw05z4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70477 uniprotkb:O35984 intact:EBI-26671524|ensembl:ENSMUSP00000094966|ensembl:ENSMUSP00000134852|ensembl:ENSMUSP00000135804|uniprotkb:Q7TT01 intact:EBI-1373614|ensembl:ENSMUSP00000040464 psi-mi:pknx1_mouse(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Prep1(gene name synonym)|uniprotkb:Pknox1(gene name)|psi-mi:Pknox1(display_short) psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671586|imex:IM-28774-1977 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006705(gene)|ensembl:ENSMUST00000097352(transcript)|ensembl:ENSMUST00000175806(transcript)|ensembl:ENSMUST00000176701(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:NP_057879.2|refseq:XP_006523917.1|refseq:XP_006523918.1|entrezgene/locuslink:18771(identity) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xm0jPdkFFT+13skBNDcjknXhBEo10090 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rigid:NPHRWC2YTw4TIOH8ssRUzDKhcxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70477 uniprotkb:O35984 intact:EBI-26671524|ensembl:ENSMUSP00000094966|ensembl:ENSMUSP00000134852|ensembl:ENSMUSP00000135804|uniprotkb:Q7TT01 intact:EBI-1373614|ensembl:ENSMUSP00000040464 psi-mi:pknx1_mouse(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Prep1(gene name synonym)|uniprotkb:Pknox1(gene name)|psi-mi:Pknox1(display_short) psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671578|imex:IM-28774-1975 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006705(gene)|ensembl:ENSMUST00000097352(transcript)|ensembl:ENSMUST00000175806(transcript)|ensembl:ENSMUST00000176701(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:NP_057879.2|refseq:XP_006523917.1|refseq:XP_006523918.1|entrezgene/locuslink:18771(identity) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xm0jPdkFFT+13skBNDcjknXhBEo10090 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rigid:NPHRWC2YTw4TIOH8ssRUzDKhcxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:O70477 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26671524|ensembl:ENSMUSP00000094966|ensembl:ENSMUSP00000134852|ensembl:ENSMUSP00000135804|uniprotkb:Q7TT01 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:pknx1_mouse(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Prep1(gene name synonym)|uniprotkb:Pknox1(gene name)|psi-mi:Pknox1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671570|imex:IM-28774-1063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000006705(gene)|ensembl:ENSMUST00000097352(transcript)|ensembl:ENSMUST00000175806(transcript)|ensembl:ENSMUST00000176701(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:NP_057879.2|refseq:XP_006523917.1|refseq:XP_006523918.1|entrezgene/locuslink:18771(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:xm0jPdkFFT+13skBNDcjknXhBEo10090 rigid:+CiEkU4GaeCX0InHxbdJdPS50rE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:O70477 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26671524|ensembl:ENSMUSP00000094966|ensembl:ENSMUSP00000134852|ensembl:ENSMUSP00000135804|uniprotkb:Q7TT01 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:pknx1_mouse(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Prep1(gene name synonym)|uniprotkb:Pknox1(gene name)|psi-mi:Pknox1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671562|imex:IM-28774-1973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000006705(gene)|ensembl:ENSMUST00000097352(transcript)|ensembl:ENSMUST00000175806(transcript)|ensembl:ENSMUST00000176701(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:NP_057879.2|refseq:XP_006523917.1|refseq:XP_006523918.1|entrezgene/locuslink:18771(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:xm0jPdkFFT+13skBNDcjknXhBEo10090 rigid:+CiEkU4GaeCX0InHxbdJdPS50rE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54943 uniprotkb:O35973 intact:EBI-1266779|uniprotkb:O54954 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671500|imex:IM-28774-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rigid:QfDYUa9cyf1BNqqrfYa1wg7mIIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54943 uniprotkb:O35973 intact:EBI-1266779|uniprotkb:O54954 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671492|imex:IM-28774-1969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rigid:QfDYUa9cyf1BNqqrfYa1wg7mIIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62515 uniprotkb:O35137 intact:EBI-26671725|ensembl:ENSMUSP00000077354|uniprotkb:P25216 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:po3f4_mouse(display_long)|uniprotkb:Brain-specific homeobox/POU domain protein 4(gene name synonym)|uniprotkb:Octamer-binding protein 9(gene name synonym)|uniprotkb:Octamer-binding transcription factor 9(gene name synonym)|uniprotkb:Pou3f4(gene name)|psi-mi:Pou3f4(display_short)|uniprotkb:Brn-4(gene name synonym)|uniprotkb:Brn4(gene name synonym)|uniprotkb:Otf9(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671761|imex:IM-28774-2419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000056854(gene)|ensembl:ENSMUST00000078229(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048839"(inner ear development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR016362(Transcription factor, homeobox/POU)|interpro:IPR017970|refseq:NP_032927.1|entrezgene/locuslink:18994(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:zoAzVJOklMQ9AlmzXYLocSvIDBc10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:Qq9MrrsaFhJ4WqDm0eNW+m8q8hU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99MY8 uniprotkb:Q61545 intact:EBI-26671879|ensembl:ENSMUSP00000088451|ensembl:ENSMUSP00000140251|uniprotkb:E9QNM2|uniprotkb:Q3U598|uniprotkb:Q80VY5|uniprotkb:Q8BM69|uniprotkb:Q8BTX0|uniprotkb:Q8BZY6 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:ash1l_mouse(display_long)|uniprotkb:ASH1-like protein(gene name synonym)|uniprotkb:Absent small and homeotic disks protein 1 homolog(gene name synonym)|uniprotkb:Ash1l(gene name)|psi-mi:Ash1l(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671942|imex:IM-28774-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028053(gene)|ensembl:ENSMUST00000090933(transcript)|ensembl:ENSMUST00000186583(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007338"(single fertilization)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048733"(sebaceous gland development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:1903699"(tarsal gland development)|go:"GO:1903709"(uterine gland development)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017956|interpro:IPR019786|interpro:IPR036427|interpro:IPR043151|interpro:IPR043319|interpro:IPR043320|reactome:R-MMU-3214841|refseq:NP_619620.3|refseq:XP_006501204.1|refseq:XP_006501205.1|entrezgene/locuslink:192195(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PZ+VDxlPdXf/cfR7jgcWF1iAbQA10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:QrUGFwbGQ8E33QnncOxHhuiJ2TM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5U4D4 uniprotkb:Q63934 intact:EBI-26671846|ensembl:ENSMUSP00000073504 intact:EBI-26671769|ensembl:ENSMUSP00000034115|uniprotkb:Q63954 psi-mi:q5u4d4_mouse(display_long)|uniprotkb:Pou6f1(gene name)|psi-mi:Pou6f1(display_short) psi-mi:po4f2_mouse(display_long)|uniprotkb:Brain-specific homeobox/POU domain protein 3B(gene name synonym)|uniprotkb:Pou4f2(gene name)|psi-mi:Pou4f2(display_short)|uniprotkb:Brn-3.2(gene name synonym)|uniprotkb:Brn3b(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671871|imex:IM-28774-1071 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009739(gene)|ensembl:ENSMUST00000073837(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|refseq:NP_001291894.1|entrezgene/locuslink:19009(identity) ensembl:ENSMUSG00000031688(gene)|ensembl:ENSMUST00000034115(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048675"(axon extension)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090259"(regulation of retinal ganglion cell axon guidance)|go:"GO:1902870"(negative regulation of amacrine cell differentiation)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6804759|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|refseq:NP_620394.2|entrezgene/locuslink:18997(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wP6H1mKwYEvA9kQCTw8UnT0Q97410090 rogid:v7ZfH8cB4fqZSxUz060RJHwoTtM10090 rigid:8DDUr4scbHTWK+RqleNwsGd9PPE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5U4D4 uniprotkb:P23812 intact:EBI-26671846|ensembl:ENSMUSP00000073504 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:q5u4d4_mouse(display_long)|uniprotkb:Pou6f1(gene name)|psi-mi:Pou6f1(display_short) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671863|imex:IM-28774-2823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009739(gene)|ensembl:ENSMUST00000073837(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|refseq:NP_001291894.1|entrezgene/locuslink:19009(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wP6H1mKwYEvA9kQCTw8UnT0Q97410090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:zm02+49WaprCHMLRL6Octo/SUQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99MY8 uniprotkb:Q07279 intact:EBI-26671879|ensembl:ENSMUSP00000088451|ensembl:ENSMUSP00000140251|uniprotkb:E9QNM2|uniprotkb:Q3U598|uniprotkb:Q80VY5|uniprotkb:Q8BM69|uniprotkb:Q8BTX0|uniprotkb:Q8BZY6 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:ash1l_mouse(display_long)|uniprotkb:ASH1-like protein(gene name synonym)|uniprotkb:Absent small and homeotic disks protein 1 homolog(gene name synonym)|uniprotkb:Ash1l(gene name)|psi-mi:Ash1l(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671950|imex:IM-28774-1073 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028053(gene)|ensembl:ENSMUST00000090933(transcript)|ensembl:ENSMUST00000186583(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007338"(single fertilization)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048733"(sebaceous gland development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:1903699"(tarsal gland development)|go:"GO:1903709"(uterine gland development)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017956|interpro:IPR019786|interpro:IPR036427|interpro:IPR043151|interpro:IPR043319|interpro:IPR043320|reactome:R-MMU-3214841|refseq:NP_619620.3|refseq:XP_006501204.1|refseq:XP_006501205.1|entrezgene/locuslink:192195(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PZ+VDxlPdXf/cfR7jgcWF1iAbQA10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:PM0Huqebj7amq+su0xIdeZs9pCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35602 uniprotkb:O35137 intact:EBI-10901180|uniprotkb:O08748|uniprotkb:Q6GT92|ensembl:ENSMUSP00000025396 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:rx_mouse(display_long)|uniprotkb:Rax(gene name)|psi-mi:Rax(display_short)|uniprotkb:Rx(gene name synonym)|uniprotkb:Retina and anterior neural fold homeobox protein(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672010|imex:IM-28774-2421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038861.2|ensembl:ENSMUSG00000024518(gene)|ensembl:ENSMUST00000025396(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007420"(brain development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060173"(limb development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR043562|entrezgene/locuslink:19434(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UKnSz8fGREf1liDEwwWURfnRwfA10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:eiM2RYHn8YaJszPZsn/BE9JOv1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91VY5 uniprotkb:Q07279 intact:EBI-26671958|ensembl:ENSMUSP00000025036|uniprotkb:Q3UR22|uniprotkb:Q6ZQ30|uniprotkb:Q99K42 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:kdm4b_mouse(display_long)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym)|uniprotkb:Kdm4b(gene name)|psi-mi:Kdm4b(display_short)|uniprotkb:Jhdm3b(gene name synonym)|uniprotkb:Jmjd2b(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672002|imex:IM-28774-1521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000025036(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|reactome:R-MMU-3214842|reactome:R-MMU-5693565|reactome:R-MMU-9018519|ensembl:ENSMUSG00000024201(gene)|refseq:NP_742144.1|entrezgene/locuslink:193796(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:no1/Cl9hnx8BspnCRA0doshbb5E10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:dtRfhS7fI2mBKDe3RTY5qf5uufw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91VY5 uniprotkb:Q04742 intact:EBI-26671958|ensembl:ENSMUSP00000025036|uniprotkb:Q3UR22|uniprotkb:Q6ZQ30|uniprotkb:Q99K42 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:kdm4b_mouse(display_long)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym)|uniprotkb:Kdm4b(gene name)|psi-mi:Kdm4b(display_short)|uniprotkb:Jhdm3b(gene name synonym)|uniprotkb:Jmjd2b(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671994|imex:IM-28774-1983 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000025036(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|reactome:R-MMU-3214842|reactome:R-MMU-5693565|reactome:R-MMU-9018519|ensembl:ENSMUSG00000024201(gene)|refseq:NP_742144.1|entrezgene/locuslink:193796(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:no1/Cl9hnx8BspnCRA0doshbb5E10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:FGRavO3d7hoX5g2IbwIe5YG/830 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04207 uniprotkb:P13864 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 intact:EBI-301927|uniprotkb:Q80ZU3|uniprotkb:Q9CSC6|uniprotkb:P97413|uniprotkb:Q9QXX6|ensembl:ENSMUSP00000004202 psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:dnmt1_mouse(display_long)|uniprotkb:Dnmt1(gene name)|psi-mi:Dnmt1(display_short)|uniprotkb:Dnmt(gene name synonym)|uniprotkb:Met1(gene name synonym)|uniprotkb:Uim(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase MmuI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672018|imex:IM-28774-1985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) refseq:NP_001186360.2|refseq:NP_001186361.1|refseq:NP_001186362.1|refseq:NP_034196.5|interpro:IPR031303|interpro:IPR043151|mint:P13864|rcsb pdb:3AV4|rcsb pdb:3AV5|rcsb pdb:3AV6|rcsb pdb:3PT6|rcsb pdb:3PT9|rcsb pdb:4DA4|rcsb pdb:5GUT|rcsb pdb:5GUV|rcsb pdb:5WY1|rcsb pdb:6W8V|rcsb pdb:6W8W|reactome:R-MMU-212300|reactome:R-MMU-4655427|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|ensembl:ENSMUST00000004202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0044026"(DNA hypermethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051718"("DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates")|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:0016458"(obsolete gene silencing)|ensembl:ENSMUSG00000004099(gene)|refseq:NP_001300940.1|entrezgene/locuslink:13433(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rogid:JgHTnDhDn4nuU6ww3jXfDPq01xY10090 rigid:0LZ3h4M2eyoPm7na6LcwTbn5a18 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43267 uniprotkb:O35160 intact:EBI-7332587|uniprotkb:Q91V43|uniprotkb:O70204|intact:MINT-4788454|uniprotkb:P70418|uniprotkb:Q62246|uniprotkb:Q91V00|uniprotkb:Q9JLG2|uniprotkb:Q920T1|ensembl:ENSMUSP00000048524 intact:EBI-26672608|ensembl:ENSMUSP00000026259|uniprotkb:Q0VB03 psi-mi:sox15_mouse(display_long)|uniprotkb:Sox15(gene name)|psi-mi:Sox15(display_short)|uniprotkb:Sox-15(gene name synonym) psi-mi:pitx3_mouse(display_long)|uniprotkb:Homeobox protein PITX3(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 3(gene name synonym)|uniprotkb:Pitx3(gene name)|psi-mi:Pitx3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672652|imex:IM-28774-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033261.1|ensembl:ENSMUSG00000041287(gene)|ensembl:ENSMUST00000047373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030154"(cell differentiation)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048627"(myoblast development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031269|interpro:IPR036910|mint:P43267|entrezgene/locuslink:20670(identity) ensembl:ENSMUSG00000025229(gene)|ensembl:ENSMUST00000026259(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014014"(negative regulation of gliogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042220"(response to cocaine)|go:"GO:0043278"(response to morphine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048666"(neuron development)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1904935"(positive regulation of cell proliferation in midbrain)|go:"GO:1990792"(cellular response to glial cell derived neurotrophic factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|refseq:NP_032878.1|entrezgene/locuslink:18742(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wj4NLG49TVaYff8+GgEYNHVEo9I10090 rogid:Par5rHJsb+hdWB2U9mxAYKMeNgM10090 rigid:8G2nBZhPvas/Q1DIcc1miRawNuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04207 uniprotkb:P25799 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672026|imex:IM-28774-1987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:0AZuFy4V4SHQmESaNIXknOfbw10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43267 uniprotkb:O35137 intact:EBI-7332587|uniprotkb:Q91V43|uniprotkb:O70204|intact:MINT-4788454|uniprotkb:P70418|uniprotkb:Q62246|uniprotkb:Q91V00|uniprotkb:Q9JLG2|uniprotkb:Q920T1|ensembl:ENSMUSP00000048524 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:sox15_mouse(display_long)|uniprotkb:Sox15(gene name)|psi-mi:Sox15(display_short)|uniprotkb:Sox-15(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672592|imex:IM-28774-2433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033261.1|ensembl:ENSMUSG00000041287(gene)|ensembl:ENSMUST00000047373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030154"(cell differentiation)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048627"(myoblast development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031269|interpro:IPR036910|mint:P43267|entrezgene/locuslink:20670(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wj4NLG49TVaYff8+GgEYNHVEo9I10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:yqbUWFIF4tfWIAvtwNr4AqfNbHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02085 uniprotkb:Q07279 intact:EBI-6049807|ensembl:ENSMUSP00000050581 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:snai1_mouse(display_long)|uniprotkb:Snai1(gene name)|psi-mi:Snai1(display_short)|uniprotkb:Sna(gene name synonym)|uniprotkb:Protein snail homolog 1(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672584|imex:IM-28774-1085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035557.1|ensembl:ENSMUSG00000042821(gene)|ensembl:ENSMUST00000052631(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:20613(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wBJPjKdtJjmqMogDVe/fBO9DzVo10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:Nt2RtCIxaG0rCnXSrh1cwP5Qe3w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62240 uniprotkb:Q07279 intact:EBI-26672525|ensembl:ENSMUSP00000061095|uniprotkb:Q3US03|uniprotkb:Q6PCX3|uniprotkb:Q9QVR9|uniprotkb:Q9R040 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:kdm5d_mouse(display_long)|uniprotkb:Histocompatibility Y antigen(gene name synonym)|uniprotkb:Histone demethylase JARID1D(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1D(gene name synonym)|uniprotkb:Protein SmcY(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5D"(gene name synonym)|uniprotkb:Kdm5d(gene name)|psi-mi:Kdm5d(display_short)|uniprotkb:Hya(gene name synonym)|uniprotkb:Jarid1d(gene name synonym)|uniprotkb:Smcy(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672576|imex:IM-28774-2835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000056673(gene)|ensembl:ENSMUST00000055032(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0002457"(T cell antigen processing and presentation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|reactome:R-MMU-3214842|refseq:NP_035549.1|entrezgene/locuslink:20592(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Xykgc4tH/CogBi2mYeFRKkL9JXY10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:4+jqltC1PpyAz/F2qVg8VDP8z40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62240 uniprotkb:Q61545 intact:EBI-26672525|ensembl:ENSMUSP00000061095|uniprotkb:Q3US03|uniprotkb:Q6PCX3|uniprotkb:Q9QVR9|uniprotkb:Q9R040 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:kdm5d_mouse(display_long)|uniprotkb:Histocompatibility Y antigen(gene name synonym)|uniprotkb:Histone demethylase JARID1D(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1D(gene name synonym)|uniprotkb:Protein SmcY(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5D"(gene name synonym)|uniprotkb:Kdm5d(gene name)|psi-mi:Kdm5d(display_short)|uniprotkb:Hya(gene name synonym)|uniprotkb:Jarid1d(gene name synonym)|uniprotkb:Smcy(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672568|imex:IM-28774-1997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000056673(gene)|ensembl:ENSMUST00000055032(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0002457"(T cell antigen processing and presentation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|reactome:R-MMU-3214842|refseq:NP_035549.1|entrezgene/locuslink:20592(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Xykgc4tH/CogBi2mYeFRKkL9JXY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:89qCf+vSrNpW2wi9OJjl7CtmpLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41230 uniprotkb:Q07279 intact:EBI-26619093|ensembl:ENSMUSP00000108203|uniprotkb:O54995|uniprotkb:Q3TYU8|uniprotkb:Q3U1X6|uniprotkb:Q3U282|uniprotkb:Q6ZQF8|uniprotkb:Q80XQ9|uniprotkb:Q9CVI4|uniprotkb:Q9D0C3|uniprotkb:Q9QVR8|uniprotkb:Q9R039 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:kdm5c_mouse(display_long)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5C"(gene name synonym)|uniprotkb:Kdm5c(gene name)|psi-mi:Kdm5c(display_short)|uniprotkb:Jarid1c(gene name synonym)|uniprotkb:Kiaa0234(gene name synonym)|uniprotkb:Smcx(gene name synonym)|uniprotkb:Xe169(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672517|imex:IM-28774-1529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P41230|reactome:R-MMU-3214842|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000025332(gene)|ensembl:ENSMUST00000112584(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|refseq:NP_038696.2|refseq:XP_006528832.1|refseq:XP_006528835.1|entrezgene/locuslink:20591(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Cz2SLt7G4flnRV/dGUoqKlwpIK410090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:5jdwKa+gahAFfpouSqkVnZWBn64 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PCN7 uniprotkb:P43241 intact:EBI-6869770|ensembl:ENSMUSP00000002502|uniprotkb:O35596|uniprotkb:O35597|uniprotkb:Q80VT6 intact:EBI-26668158|ensembl:ENSMUSP00000031650 psi-mi:hltf_mouse(display_long)|uniprotkb:Hltf(gene name)|psi-mi:Hltf(display_short)|uniprotkb:Smarca3(gene name synonym)|uniprotkb:Snf2l3(gene name synonym)|uniprotkb:Zbu1(gene name synonym)|uniprotkb:P113(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:TNF-response element-binding protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:cdx2_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 2(gene name synonym)|uniprotkb:Cdx2(gene name)|psi-mi:Cdx2(display_short)|uniprotkb:Cdx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672509|imex:IM-28774-1995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000002502(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|reactome:R-MMU-8866654|ensembl:ENSMUSG00000002428(gene)|refseq:XP_006535491.1|refseq:NP_033236.2|entrezgene/locuslink:20585(identity) ensembl:ENSMUSG00000029646(gene)|ensembl:ENSMUST00000031650(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0060711"(labyrinthine layer development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_031699.2|entrezgene/locuslink:12591(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iZhxC9wBoKZ9ZYCaEnNUbg1x2i410090 rogid:1XpCK7ehS+3cgrG8vncU1t2kkpQ10090 rigid:t11NS2eZWkIvbFGskqdwC3Xbofs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61045 uniprotkb:P53762 intact:EBI-78890|uniprotkb:O70284|uniprotkb:P70183|ensembl:ENSMUSP00000020071 intact:EBI-78852|uniprotkb:Q921F3|uniprotkb:Q60661|ensembl:ENSMUSP00000099810 psi-mi:sim1_mouse(display_long)|uniprotkb:Sim1(gene name)|psi-mi:Sim1(display_short) psi-mi:arnt_mouse(display_long)|uniprotkb:Arnt(gene name)|psi-mi:Arnt(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672501|imex:IM-28774-1083 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035506.2|ensembl:ENSMUSG00000019913(gene)|ensembl:ENSMUST00000020071(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR010578(Single-minded, C-terminal)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|refseq:XP_006512690.1|entrezgene/locuslink:20464(identity) refseq:NP_001032826.1|ensembl:ENSMUSG00000015522(gene)|ensembl:ENSMUST00000102749(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4ZP4|rcsb pdb:4ZPH|rcsb pdb:4ZPK|rcsb pdb:4ZPR|rcsb pdb:4ZQD|rcsb pdb:5NJ8|rcsb pdb:5SY5|rcsb pdb:5SY7|rcsb pdb:6E3S|rcsb pdb:6E3T|rcsb pdb:6E3U|reactome:R-MMU-1234158|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144|dip:DIP-280N|entrezgene/locuslink:11863(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OyST+SKNJJKrvTqDUaK84zdA5a810090 rogid:NYJuNrii1HcGy0q0T0NDNXiPiKE10090 rigid:row1PkOa5QlvziMcb3IM6GSlE00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61045 uniprotkb:P53762 intact:EBI-78890|uniprotkb:O70284|uniprotkb:P70183|ensembl:ENSMUSP00000020071 intact:EBI-78852|uniprotkb:Q921F3|uniprotkb:Q60661|ensembl:ENSMUSP00000099810 psi-mi:sim1_mouse(display_long)|uniprotkb:Sim1(gene name)|psi-mi:Sim1(display_short) psi-mi:arnt_mouse(display_long)|uniprotkb:Arnt(gene name)|psi-mi:Arnt(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672493|imex:IM-28774-1081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035506.2|ensembl:ENSMUSG00000019913(gene)|ensembl:ENSMUST00000020071(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR010578(Single-minded, C-terminal)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|refseq:XP_006512690.1|entrezgene/locuslink:20464(identity) refseq:NP_001032826.1|ensembl:ENSMUSG00000015522(gene)|ensembl:ENSMUST00000102749(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4ZP4|rcsb pdb:4ZPH|rcsb pdb:4ZPK|rcsb pdb:4ZPR|rcsb pdb:4ZQD|rcsb pdb:5NJ8|rcsb pdb:5SY5|rcsb pdb:5SY7|rcsb pdb:6E3S|rcsb pdb:6E3T|rcsb pdb:6E3U|reactome:R-MMU-1234158|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144|dip:DIP-280N|entrezgene/locuslink:11863(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OyST+SKNJJKrvTqDUaK84zdA5a810090 rogid:NYJuNrii1HcGy0q0T0NDNXiPiKE10090 rigid:row1PkOa5QlvziMcb3IM6GSlE00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17433 uniprotkb:Q04742 intact:EBI-607588|ensembl:ENSMUSP00000002180|uniprotkb:Q99L57 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:spi1_mouse(display_long)|uniprotkb:Spi1(gene name)|psi-mi:Spi1(display_short)|uniprotkb:Sfpi1(gene name synonym)|uniprotkb:Sfpi-1(gene name synonym)|uniprotkb:31 kDa-transforming protein(gene name synonym)|uniprotkb:SFFV proviral integration 1 protein(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672485|imex:IM-28774-1993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000002111(gene)|ensembl:ENSMUST00000002180(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001944"(vasculature development)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0002316"(follicular B cell differentiation)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002572"(pro-T cell differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034401"(obsolete chromatin organization involved in regulation of transcription)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043314"(negative regulation of neutrophil degranulation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0060033"(anatomical structure regression)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:0120186"(negative regulation of protein localization to chromatin)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901674"(regulation of histone H3-K27 acetylation)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1904238"(pericyte cell differentiation)|go:"GO:1905036"(positive regulation of antifungal innate immune response)|go:"GO:1905453"(regulation of myeloid progenitor cell differentiation)|go:"GO:2000529"(positive regulation of myeloid dendritic cell chemotaxis)|interpro:IPR000418(Ets)|interpro:IPR036388|rcsb pdb:1PUE|rcsb pdb:5W3G|interpro:IPR036390|refseq:NP_035485.1|entrezgene/locuslink:20375(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oX+T3U9B+gJ3Aao0rDVm4CHqSR410090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:Q1q/+WulQbXXnSoTr5aJYka/H88 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60749 uniprotkb:Q60749 intact:EBI-519077|uniprotkb:A2ACH3|uniprotkb:Q7M4N5|uniprotkb:Q3U8T3|uniprotkb:Q60735|uniprotkb:Q99M33|ensembl:ENSMUSP00000066516|ensembl:ENSMUSP00000115402|uniprotkb:B2KG38 intact:EBI-519077|uniprotkb:A2ACH3|uniprotkb:Q7M4N5|uniprotkb:Q3U8T3|uniprotkb:Q60735|uniprotkb:Q99M33|ensembl:ENSMUSP00000066516|ensembl:ENSMUSP00000115402|uniprotkb:B2KG38 psi-mi:khdr1_mouse(display_long)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:Khdrbs1(gene name)|psi-mi:Khdrbs1(display_short) psi-mi:khdr1_mouse(display_long)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:Khdrbs1(gene name)|psi-mi:Khdrbs1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672469|imex:IM-28774-2833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028790(gene)|ensembl:ENSMUST00000066257(transcript)|ensembl:ENSMUST00000129342(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q60749|reactome:R-MMU-8849468|refseq:NP_035447.3|dip:DIP-2861N|entrezgene/locuslink:20218(identity) ensembl:ENSMUSG00000028790(gene)|ensembl:ENSMUST00000066257(transcript)|ensembl:ENSMUST00000129342(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q60749|reactome:R-MMU-8849468|refseq:NP_035447.3|dip:DIP-2861N|entrezgene/locuslink:20218(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FtKudvPZeoFATHi0fUbnPsJgons10090 rogid:FtKudvPZeoFATHi0fUbnPsJgons10090 rigid:X/G18zSOtRrpMs4Rl98WXEX8FFs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28705 uniprotkb:P35396 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 intact:EBI-1809541|uniprotkb:P37239|ensembl:ENSMUSP00000002320 psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:ppard_mouse(display_long)|uniprotkb:Ppard(gene name)|psi-mi:Ppard(display_short)|uniprotkb:Nr1c2(gene name synonym)|uniprotkb:Pparb(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 2(gene name synonym)|uniprotkb:Nuclear hormone receptor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672461|imex:IM-28774-1991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) refseq:NP_035275.1|dip:DIP-29851N|ensembl:ENSMUSG00000002250(gene)|ensembl:ENSMUST00000002320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006776"(vitamin A metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008366"(axon ensheathment)|go:"GO:0008544"(epidermis development)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009749"(response to glucose)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009987"(cellular process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016501"(prostacyclin receptor activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033993"(response to lipid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046697"(decidualization)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070539"(linoleic acid binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003075(Peroxisome proliferator-activated receptor, beta)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-383280|reactome:R-MMU-5362517|entrezgene/locuslink:19015(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rogid:R8m8kywrVlTqSv8CI1m0q6NeBls10090 rigid:+xwaL6ik+7wB2Tyz89WipyB1rMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28705 uniprotkb:O54915 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 intact:EBI-11892436|ensembl:ENSMUSP00000023504 psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:nr1i2_mouse(display_long)|uniprotkb:Nr1i2(gene name)|psi-mi:Nr1i2(display_short)|uniprotkb:Pxr(gene name synonym)|uniprotkb:Orphan nuclear receptor PXR(gene name synonym)|uniprotkb:Pregnane X receptor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672453|imex:IM-28774-1527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) refseq:NP_001091874.1|refseq:NP_035066.1|refseq:XP_006521909.1|refseq:XP_006521911.1|ensembl:ENSMUSG00000022809(gene)|ensembl:ENSMUST00000023504(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042738"|go:"GO:0042908"(xenobiotic transport)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|reactome:R-MMU-4090294|entrezgene/locuslink:18171(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rogid:o7EexQngGpeyhpov78niLRiK/I410090 rigid:KiNF+Ha71HDTCgm4Z1jJ3jcpryU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28705 uniprotkb:O54915 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 intact:EBI-11892436|ensembl:ENSMUSP00000023504 psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:nr1i2_mouse(display_long)|uniprotkb:Nr1i2(gene name)|psi-mi:Nr1i2(display_short)|uniprotkb:Pxr(gene name synonym)|uniprotkb:Orphan nuclear receptor PXR(gene name synonym)|uniprotkb:Pregnane X receptor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672445|imex:IM-28774-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) refseq:NP_001091874.1|refseq:NP_035066.1|refseq:XP_006521909.1|refseq:XP_006521911.1|ensembl:ENSMUSG00000022809(gene)|ensembl:ENSMUST00000023504(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042738"|go:"GO:0042908"(xenobiotic transport)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|reactome:R-MMU-4090294|entrezgene/locuslink:18171(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rogid:o7EexQngGpeyhpov78niLRiK/I410090 rigid:KiNF+Ha71HDTCgm4Z1jJ3jcpryU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88621 uniprotkb:P28705 intact:EBI-7457430|intact:MINT-4998752|uniprotkb:Q9QZL5|uniprotkb:Q9R241|ensembl:ENSMUSP00000036591 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 psi-mi:foxh1_mouse(display_long)|uniprotkb:Foxh1(gene name)|psi-mi:Foxh1(display_short)|uniprotkb:Fast1(gene name synonym)|uniprotkb:Fast2(gene name synonym)|uniprotkb:Forkhead activin signal transducer 1(gene name synonym)|uniprotkb:Forkhead activin signal transducer 2(gene name synonym) psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672437|imex:IM-28774-2831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032015.1|refseq:XP_006520499.1|ensembl:ENSMUSG00000033837(gene)|ensembl:ENSMUST00000037824(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:O88621|reactome:R-MMU-1181150|reactome:R-MMU-1502540|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|entrezgene/locuslink:14106(identity) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) - function:"Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element)"|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/wralkUfGdtYTuVGaOKelphRTTc10090 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rigid:cKQ4qUKKX7ow2XS85fjnAcjXZIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28705 uniprotkb:O35627 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 intact:EBI-26672385|ensembl:ENSMUSP00000005820|uniprotkb:O35628|uniprotkb:Q3V008 psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:nr1i3_mouse(display_long)|uniprotkb:Constitutive androstane receptor(gene name synonym)|uniprotkb:Orphan nuclear receptor MB67(gene name synonym)|uniprotkb:Nr1i3(gene name)|psi-mi:Nr1i3(display_short)|uniprotkb:Car(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672429|imex:IM-28774-2429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) ensembl:ENSMUSG00000005677(gene)|ensembl:ENSMUST00000005820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1XLS|rcsb pdb:1XNX|reactome:R-MMU-383280|refseq:NP_001229991.1|refseq:NP_001229992.1|refseq:NP_033933.2|entrezgene/locuslink:12355(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rogid:EGzVHVBjaTrFB5EzRVtj9sBWiFs10090 rigid:LQzTpPtoK6hr5TQbviBMAN9vNVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28700 uniprotkb:P35396 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 intact:EBI-1809541|uniprotkb:P37239|ensembl:ENSMUSP00000002320 psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:ppard_mouse(display_long)|uniprotkb:Ppard(gene name)|psi-mi:Ppard(display_short)|uniprotkb:Nr1c2(gene name synonym)|uniprotkb:Pparb(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 2(gene name synonym)|uniprotkb:Nuclear hormone receptor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672377|imex:IM-28774-2829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|entrezgene/locuslink:20181(identity) refseq:NP_035275.1|dip:DIP-29851N|ensembl:ENSMUSG00000002250(gene)|ensembl:ENSMUST00000002320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006776"(vitamin A metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008366"(axon ensheathment)|go:"GO:0008544"(epidermis development)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009749"(response to glucose)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009987"(cellular process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016501"(prostacyclin receptor activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033993"(response to lipid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046697"(decidualization)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070539"(linoleic acid binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003075(Peroxisome proliferator-activated receptor, beta)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-383280|reactome:R-MMU-5362517|entrezgene/locuslink:19015(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 rogid:R8m8kywrVlTqSv8CI1m0q6NeBls10090 rigid:fBDelTzDFeV4ANDHrBLV8sQ715g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28700 uniprotkb:P23204 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 intact:EBI-5273083|ensembl:ENSMUSP00000059719|ensembl:ENSMUSP00000105049|ensembl:ENSMUSP00000105050 psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:ppara_mouse(display_long)|uniprotkb:Ppara(gene name)|psi-mi:Ppara(display_short)|uniprotkb:Nr1c1(gene name synonym)|uniprotkb:Ppar(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672369|imex:IM-28774-3253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|entrezgene/locuslink:20181(identity) refseq:NP_001106889.1|refseq:NP_035274.2|refseq:XP_011243818.1|refseq:XP_011243819.1|refseq:XP_011243821.1|refseq:XP_006520682.1|refseq:XP_006520683.1|refseq:XP_006520684.1|refseq:XP_006520685.1|refseq:XP_006520686.1|dip:DIP-5958N|interpro:IPR003076(Peroxisome proliferator-activated receptor, alpha)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-9707564|ensembl:ENSMUSG00000022383(gene)|ensembl:ENSMUST00000057979(transcript)|ensembl:ENSMUST00000109422(transcript)|ensembl:ENSMUST00000109423(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010876"(lipid localization)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033993"(response to lipid)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|entrezgene/locuslink:19013(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 rogid:XMx/fxUdTAyW04GLitSaO72WfXU10090 rigid:Dlpz/e3vGc+pM447hVeNvf8l4ek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IY51 uniprotkb:P09016 intact:EBI-12117432|ensembl:ENSP00000355162|uniprotkb:Q96LP5 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:tigd4_human(display_long)|uniprotkb:TIGD4(gene name)|psi-mi:TIGD4(display_short) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672361|imex:IM-28774-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169989(gene)|ensembl:ENST00000304337(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|go:"GO:0003677"(DNA binding)|refseq:NP_663772.1|refseq:XP_005262864.1|entrezgene/locuslink:201798(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AjNDbsuZU8pExrK7i33Vag48NeA9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:CRknl/JIuK1j6OKxzhnGmIOmV4Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04741 uniprotkb:P19419 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4 psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672353|imex:IM-28774-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N|entrezgene/locuslink:2002(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606 rigid:j1zHZI/2zUZxKUiYWE0Qd2cAxgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NAM6 uniprotkb:Q8NAM6 intact:EBI-7252920|intact:MINT-1184273|uniprotkb:Q3MIQ2|intact:EBI-28968977|ensembl:ENSP00000321963|ensembl:ENSP00000480210 intact:EBI-7252920|intact:MINT-1184273|uniprotkb:Q3MIQ2|intact:EBI-28968977|ensembl:ENSP00000321963|ensembl:ENSP00000480210 psi-mi:zsca4_human(display_long)|uniprotkb:ZSCAN4(gene name)|psi-mi:ZSCAN4(display_short)|uniprotkb:ZNF494(gene name synonym)|uniprotkb:Zinc finger protein 494(gene name synonym) psi-mi:zsca4_human(display_long)|uniprotkb:ZSCAN4(gene name)|psi-mi:ZSCAN4(display_short)|uniprotkb:ZNF494(gene name synonym)|uniprotkb:Zinc finger protein 494(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672337|imex:IM-28774-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000321963|ensembl:ENSP00000480210|refseq:XP_011524909.1|refseq:NP_689890.1|ensembl:ENSG00000180532(gene)|ensembl:ENST00000318203(transcript)|ensembl:ENST00000612521(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016881947.1|entrezgene/locuslink:201516(identity) ensembl:ENSP00000321963|ensembl:ENSP00000480210|refseq:XP_011524909.1|refseq:NP_689890.1|ensembl:ENSG00000180532(gene)|ensembl:ENST00000318203(transcript)|ensembl:ENST00000612521(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016881947.1|entrezgene/locuslink:201516(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint function:May be involved in transcriptional regulation|comment:mint|comment:homomint figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tGa8j55dyWM+OzeyL6koubpXCKU9606 rogid:tGa8j55dyWM+OzeyL6koubpXCKU9606 rigid:WAS5E9CfX45u2CU8PoOttvolT7M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVC4 uniprotkb:Q8N653 intact:EBI-21373561|ensembl:ENSP00000306756|uniprotkb:A8K203 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zn584_human(display_long)|uniprotkb:ZNF584(gene name)|psi-mi:ZNF584(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672329|imex:IM-28774-3251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171574(gene)|ensembl:ENST00000306910(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001304931.1|refseq:NP_775819.1|entrezgene/locuslink:201514(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yNbCTgbAiRp4TtxJK1y7yQgo5JU9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:YOvTU5VNh2dXyZzIgDhGWiJNWd4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TYI2 uniprotkb:P97760 intact:EBI-26672300 intact:EBI-309987|ensembl:ENSMUSP00000105147|intact:EBI-5744135|uniprotkb:Q99M46 psi-mi:q3tyi2_mouse(display_long)|uniprotkb:Polr2j(gene name)|psi-mi:Polr2j(display_short) psi-mi:rpb3_mouse(display_long)|uniprotkb:Polr2c(gene name)|psi-mi:Polr2c(display_short)|uniprotkb:Rpo2-3(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672321|imex:IM-28774-2827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_035423.2|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|entrezgene/locuslink:20022(identity) ensembl:ENSMUSG00000031783(gene)|ensembl:ENSMUST00000109521(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|reactome:R-MMU-9018519|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|refseq:NP_033116.2|entrezgene/locuslink:20021(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:lVeRAU7ZwTpO9drt04ywfrfbUA410090 rogid:MHf6CjhDOFphHzay+Lu70SOjKXU10090 rigid:VCQdQZP5WzjZldwPokY9Ai5BhWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TYI2 uniprotkb:P97760 intact:EBI-26672300 intact:EBI-309987|ensembl:ENSMUSP00000105147|intact:EBI-5744135|uniprotkb:Q99M46 psi-mi:q3tyi2_mouse(display_long)|uniprotkb:Polr2j(gene name)|psi-mi:Polr2j(display_short) psi-mi:rpb3_mouse(display_long)|uniprotkb:Polr2c(gene name)|psi-mi:Polr2c(display_short)|uniprotkb:Rpo2-3(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672313|imex:IM-28774-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_035423.2|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|entrezgene/locuslink:20022(identity) ensembl:ENSMUSG00000031783(gene)|ensembl:ENSMUST00000109521(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|reactome:R-MMU-9018519|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|refseq:NP_033116.2|entrezgene/locuslink:20021(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:lVeRAU7ZwTpO9drt04ywfrfbUA410090 rogid:MHf6CjhDOFphHzay+Lu70SOjKXU10090 rigid:VCQdQZP5WzjZldwPokY9Ai5BhWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35134 uniprotkb:P25425 intact:EBI-26672234|ensembl:ENSMUSP00000060858|uniprotkb:Q7TSA9 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 psi-mi:rpa1_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:Polr1a(gene name)|psi-mi:Polr1a(display_short)|uniprotkb:Rpa1(gene name synonym)|uniprotkb:Rpo1-4(gene name synonym) psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672292|imex:IM-28774-1525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049553(gene)|ensembl:ENSMUST00000055296(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033114.3|entrezgene/locuslink:20019(identity) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CsIy49qIGfvmY/epR1XQ+Z54ckE10090 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rigid:4gv9FtaLrbTfEduT0x0bRj0WDz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35134 uniprotkb:P03966 intact:EBI-26672234|ensembl:ENSMUSP00000060858|uniprotkb:Q7TSA9 intact:EBI-647752|uniprotkb:Q61978|ensembl:ENSMUSP00000045993|ensembl:ENSMUSP00000114225 psi-mi:rpa1_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:Polr1a(gene name)|psi-mi:Polr1a(display_short)|uniprotkb:Rpa1(gene name synonym)|uniprotkb:Rpo1-4(gene name synonym) psi-mi:mycn_mouse(display_long)|uniprotkb:Mycn(gene name)|psi-mi:Mycn(display_short)|uniprotkb:Nmyc(gene name synonym)|uniprotkb:Nmyc1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672284|imex:IM-28774-1989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049553(gene)|ensembl:ENSMUST00000055296(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033114.3|entrezgene/locuslink:20019(identity) refseq:NP_032735.3|dip:DIP-49592N|ensembl:ENSMUSG00000037169(gene)|ensembl:ENSMUST00000043396(transcript)|ensembl:ENSMUST00000130990(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019900"(kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|entrezgene/locuslink:18109(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CsIy49qIGfvmY/epR1XQ+Z54ckE10090 rogid:J+RjU57FyHczGnzHYpNaUKOiw6k10090 rigid:0dEcpJmsGrPs98BNCFlG5/n/YNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35134 uniprotkb:Q61545 intact:EBI-26672234|ensembl:ENSMUSP00000060858|uniprotkb:Q7TSA9 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rpa1_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:Polr1a(gene name)|psi-mi:Polr1a(display_short)|uniprotkb:Rpa1(gene name synonym)|uniprotkb:Rpo1-4(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672276|imex:IM-28774-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049553(gene)|ensembl:ENSMUST00000055296(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033114.3|entrezgene/locuslink:20019(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CsIy49qIGfvmY/epR1XQ+Z54ckE10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:+nmNcSO2WkttctvO1SixId/gtxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:O35134 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-26672234|ensembl:ENSMUSP00000060858|uniprotkb:Q7TSA9 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:rpa1_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:Polr1a(gene name)|psi-mi:Polr1a(display_short)|uniprotkb:Rpa1(gene name synonym)|uniprotkb:Rpo1-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672268|imex:IM-28774-1079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000049553(gene)|ensembl:ENSMUST00000055296(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033114.3|entrezgene/locuslink:20019(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:CsIy49qIGfvmY/epR1XQ+Z54ckE10090 rigid:8tSSFKd8wGCRoziLgKEily9r1zk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70700 uniprotkb:F8VPR5 intact:EBI-26672187|ensembl:ENSMUSP00000099494|uniprotkb:Q3UMX7 intact:EBI-10989694|ensembl:ENSMUSP00000023165 psi-mi:rpa2_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym)|uniprotkb:Polr1b(gene name)|psi-mi:Polr1b(display_short)|uniprotkb:Rpa2(gene name synonym)|uniprotkb:Rpo1-2(gene name synonym) psi-mi:f8vpr5_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672226|imex:IM-28774-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027395(gene)|ensembl:ENSMUST00000103205(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0007566"(embryo implantation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0014029"(neural crest formation)|go:"GO:0017126"(nucleologenesis)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033112.2|entrezgene/locuslink:20017(identity) refseq:NP_001020603.1|ensembl:ENSMUSG00000022521(gene)|ensembl:ENSMUST00000023165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:12914(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xfiED4Nca+YAmqV5SXedNnIKQY010090 rogid:9K1igrA8QbILB/vG1/XLKh9kzJM10090 rigid:zzecopwBCLNx1PIsppHZPCTmG2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51450 uniprotkb:Q61545 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672179|imex:IM-28774-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|entrezgene/locuslink:19885(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:9uNxoLys/KSKr4cSoTJU5It40u0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99M28 uniprotkb:P23812 intact:EBI-8339636|uniprotkb:Q3TMJ1|intact:MINT-4124387|uniprotkb:Q922H8|ensembl:ENSMUSP00000085867|ensembl:ENSMUSP00000126345 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:rnps1_mouse(display_long)|uniprotkb:Rnps1(gene name)|psi-mi:Rnps1(display_short) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672171|imex:IM-28774-2427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073596.1|refseq:NP_001073597.1|refseq:NP_033096.2|refseq:XP_017172851.1|ensembl:ENSMUSG00000034681(gene)|ensembl:ENSMUST00000088512(transcript)|ensembl:ENSMUST00000163717(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q99M28|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957|entrezgene/locuslink:19826(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - comment:mint|function:"Part of pre- and post-splicing multiprotein mRNP complexes. Enhances the formation of the ATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 and SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner. Participates in mRNA 3'-end cleavage. Involved in RENT2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Also mediates increase of mRNA abundance and translational efficiency. Binds spliced mRNA 20-25 nt upstream of exon-exon junctions" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nANu/nh/pD/F6dYE2Sa28OegPGs10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:nrLfjYgSFMbbHqQ2kbh4nrcy0kw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z205 uniprotkb:Q8K5B8 intact:EBI-26672134|ensembl:ENSMUSP00000148739 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:rfxk_mouse(display_long)|uniprotkb:Ankyrin repeat-containing adapter protein Tvl-1(gene name synonym)|uniprotkb:Regulatory factor X subunit B(gene name synonym)|uniprotkb:Regulatory factor X-associated ankyrin-containing protein(gene name synonym)|uniprotkb:Rfxank(gene name)|psi-mi:Rfxank(display_short)|uniprotkb:Rfxb(gene name synonym)|uniprotkb:Tvl1(gene name synonym) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672163|imex:IM-28774-2425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036120(gene)|ensembl:ENSMUST00000212320(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017362(DNA-binding, RFXANK)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001020760.1|refseq:NP_035396.1|entrezgene/locuslink:19727(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KIPun2JlrxVeu5/237St+5P017410090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:51ifQ8UA3z6o0vChU3bZP0/vzY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48379 uniprotkb:Q61660 intact:EBI-3043952|ensembl:ENSMUSP00000002444|uniprotkb:Q8BXR3 intact:EBI-26672074|ensembl:ENSMUSP00000038351|uniprotkb:Q3US42 psi-mi:rfx2_mouse(display_long)|uniprotkb:Rfx2(gene name)|psi-mi:Rfx2(display_short)|uniprotkb:Regulatory factor X 2(gene name synonym) psi-mi:foxj1_mouse(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 4(gene name synonym)|uniprotkb:Foxj1(gene name)|psi-mi:Foxj1(display_short)|uniprotkb:Hfh4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672126|imex:IM-28774-1523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024206(gene)|ensembl:ENSMUST00000002444(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001675"(acrosome assembly)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|refseq:NP_033082.1|refseq:NP_082063.1|entrezgene/locuslink:19725(identity) ensembl:ENSMUSG00000034227(gene)|ensembl:ENSMUST00000036215(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002508"(central tolerance induction)|go:"GO:0002635"(negative regulation of germinal center formation)|go:"GO:0002897"(positive regulation of central B cell tolerance induction)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033085"(negative regulation of T cell differentiation in thymus)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035082"(axoneme assembly)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035502"(metanephric part of ureteric bud development)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0060271"(cilium assembly)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060429"(epithelium development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0072016"(glomerular parietal epithelial cell development)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901248"(positive regulation of lung ciliated cell differentiation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_032266.3|refseq:XP_006532332.1|entrezgene/locuslink:15223(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1pdvERwU8gFjVZXQmwVm3HYiG0010090 rogid:BSr15igh+/BMMsDBNAKmBG498MQ10090 rigid:qQzKFutsre7/u8+e4k9EFaZGicU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VIG1 uniprotkb:Q61545 intact:EBI-2312802|uniprotkb:A0JNY8|uniprotkb:Q155C6|uniprotkb:Q3U0W0|uniprotkb:Q4VAD6|uniprotkb:Q9CW43|ensembl:ENSMUSP00000079231|ensembl:ENSMUSP00000109076 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rest_mouse(display_long)|uniprotkb:Rest(gene name)|psi-mi:Rest(display_short)|uniprotkb:Nrsf(gene name synonym)|uniprotkb:Neural-restrictive silencer factor(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672066|imex:IM-28774-2423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006534905.1|refseq:NP_035393.2|ensembl:ENSMUSG00000029249(gene)|ensembl:ENSMUST00000080359(transcript)|ensembl:ENSMUST00000113449(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2000706"(negative regulation of dense core granule biogenesis)|go:"GO:2000740"(negative regulation of mesenchymal stem cell differentiation)|go:"GO:2000798"(negative regulation of amniotic stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027757|interpro:IPR036236|mint:Q8VIG1|reactome:R-MMU-3214815|entrezgene/locuslink:19712(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:a2nJenbqqCXCUbKM//5DZQ/hz7I10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:oQiBWlMjFv4vhu+WxhuZJphx3bA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61103 uniprotkb:Q07279 intact:EBI-5691800|uniprotkb:Q3UNP5|uniprotkb:Q60663|uniprotkb:Q9QYA3|ensembl:ENSMUSP00000120125 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:requ_mouse(display_long)|uniprotkb:Dpf2(gene name)|psi-mi:Dpf2(display_short)|uniprotkb:Baf45d(gene name synonym)|uniprotkb:Req(gene name synonym)|uniprotkb:Ubid4(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:Protein requiem(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672058|imex:IM-28774-1077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035392.1|refseq:NP_001278007.1|dip:DIP-59247N|ensembl:ENSMUSG00000024826(gene)|ensembl:ENSMUST00000136983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q61103|entrezgene/locuslink:19708(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1KI7KoHStxGVEX0yT6Et10s5M/810090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:/ZCf2OvZaGD4mw5yzg7+VgTUYLY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04863 uniprotkb:Q9WTK5 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672050|imex:IM-28774-2825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)|entrezgene/locuslink:19698(identity) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6|entrezgene/locuslink:18034(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 rigid:fld3GPiN1kklyKOxE4iMckY1GBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04863 uniprotkb:P25799 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672042|imex:IM-28774-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)|entrezgene/locuslink:19698(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:9bQH8Ypyc3NPVY6gZ9Mb0w8vemM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04207 uniprotkb:Q9WTK5 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672034|imex:IM-28774-1075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6|entrezgene/locuslink:18034(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 rigid:nt8UvyqW/Eu3OMrLQYKXwx8c4yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43267 uniprotkb:P70217 intact:EBI-7332587|uniprotkb:Q91V43|uniprotkb:O70204|intact:MINT-4788454|uniprotkb:P70418|uniprotkb:Q62246|uniprotkb:Q91V00|uniprotkb:Q9JLG2|uniprotkb:Q920T1|ensembl:ENSMUSP00000048524 intact:EBI-925264|uniprotkb:Q2VPB0|uniprotkb:A2ASM5|uniprotkb:Q2VPB1|uniprotkb:Q64177|ensembl:ENSMUSP00000001872 psi-mi:sox15_mouse(display_long)|uniprotkb:Sox15(gene name)|psi-mi:Sox15(display_short)|uniprotkb:Sox-15(gene name synonym) psi-mi:hxd13_mouse(display_long)|uniprotkb:Hoxd13(gene name)|psi-mi:Hoxd13(display_short)|uniprotkb:Hox-4.8(gene name synonym)|uniprotkb:Homeobox protein Hox-4.8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672600|imex:IM-28774-1531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033261.1|ensembl:ENSMUSG00000041287(gene)|ensembl:ENSMUST00000047373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030154"(cell differentiation)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048627"(myoblast development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031269|interpro:IPR036910|mint:P43267|entrezgene/locuslink:20670(identity) refseq:NP_032301.2|ensembl:ENSMUSG00000001819(gene)|ensembl:ENSMUST00000001872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030539"(male genitalia development)|go:"GO:0033574"(response to testosterone)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060602"(branch elongation of an epithelium)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|mint:P70217|entrezgene/locuslink:15433(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wj4NLG49TVaYff8+GgEYNHVEo9I10090 rogid:FWeR98eKeTKa8R6EG03n7Gelgi410090 rigid:2C9uLKxwNEENgU/n7P4xLFx9Kmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42227 uniprotkb:Q5U4D4 intact:EBI-602878|uniprotkb:A2A5D1|uniprotkb:B7ZC17|ensembl:ENSMUSP00000120152 intact:EBI-26671846|ensembl:ENSMUSP00000073504 psi-mi:stat3_mouse(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:Stat3(gene name)|psi-mi:Stat3(display_short)|uniprotkb:Aprf(gene name synonym) psi-mi:q5u4d4_mouse(display_long)|uniprotkb:Pou6f1(gene name)|psi-mi:Pou6f1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672883|imex:IM-28774-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_998824.1|refseq:NP_998825.1|dip:DIP-442N|ensembl:ENSMUSG00000004040(gene)|ensembl:ENSMUST00000127638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|mint:P42227|rcsb pdb:1BG1|rcsb pdb:3CWG|rcsb pdb:4E68|rcsb pdb:4ZIA|reactome:R-MMU-1059683|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6783783|reactome:R-MMU-6785807|reactome:R-MMU-8849474|reactome:R-MMU-8854691|reactome:R-MMU-8875791|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9008059|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-8983432|entrezgene/locuslink:20848(identity) ensembl:ENSMUSG00000009739(gene)|ensembl:ENSMUST00000073837(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|refseq:NP_001291894.1|entrezgene/locuslink:19009(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jWu9RTbZkTUtGrXQlg1K79zHowM10090 rogid:wP6H1mKwYEvA9kQCTw8UnT0Q97410090 rigid:m9+CcqCLWVpkSzVFoGUDZ99eL3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42232 uniprotkb:P09632 intact:EBI-617454|ensembl:ENSMUSP00000004143|ensembl:ENSMUSP00000102981|uniprotkb:Q541Q5|uniprotkb:Q60804|uniprotkb:Q8K3Q1|uniprotkb:Q9JKM1|uniprotkb:Q9R0X8|uniprotkb:A2A5D5 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:sta5b_mouse(display_long)|uniprotkb:Stat5b(gene name)|psi-mi:Stat5b(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672891|imex:IM-28774-2437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020919(gene)|ensembl:ENSMUST00000004143(transcript)|ensembl:ENSMUST00000107358(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001553"(luteinization)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007548"(sex differentiation)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019915"(lipid storage)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046543"(development of secondary female sexual characteristics)|go:"GO:0046544"(development of secondary male sexual characteristics)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070669"(response to interleukin-2)|go:"GO:0070670"(response to interleukin-4)|go:"GO:0070672"(response to interleukin-15)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097531"(mast cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035858|interpro:IPR035886|interpro:IPR036535|interpro:IPR036860|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-512988|reactome:R-MMU-8854691|reactome:R-MMU-8983432|reactome:R-MMU-8985947|reactome:R-MMU-9020558|reactome:R-MMU-9020958|reactome:R-MMU-982772|refseq:NP_001107035.1|refseq:NP_035619.3|refseq:XP_017169892.1|dip:DIP-898N|entrezgene/locuslink:20851(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BEl9ugwAhh8tuSA/6WCoHXlzy3c10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:6EOICvTqRqLw9KvJX/2b/BgsaQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54826 uniprotkb:A0A087WSP5 intact:EBI-8459555|uniprotkb:Q6NS43|intact:MINT-4087317|ensembl:ENSMUSP00000028076|ensembl:ENSMUSP00000110328 intact:EBI-26672841|ensembl:ENSMUSP00000141132 psi-mi:af10_mouse(display_long)|uniprotkb:Mllt10(gene name)|psi-mi:Mllt10(display_short)|uniprotkb:Af10(gene name synonym) psi-mi:a0a087wsp5_mouse(display_long)|uniprotkb:Stat1(gene name)|psi-mi:Stat1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672867|imex:IM-28774-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001239489.1|refseq:NP_034934.2|refseq:XP_006497440.2|dip:DIP-58954N|ensembl:ENSMUSG00000026743(gene)|ensembl:ENSMUST00000028076(transcript)|ensembl:ENSMUST00000114680(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O54826|entrezgene/locuslink:17354(identity) ensembl:ENSMUSG00000026104(gene)|ensembl:ENSMUST00000186057(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042393"(histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001192242.1|entrezgene/locuslink:20846(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GtuZGrk+mN3Rrx1+4h10iHG05Us10090 rogid:nBdfBlMDBVA6J1VXNgBlgTNCbHg10090 rigid:IsxiW+862MSQvBmXI3aKV8yZ+hY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BXP5 uniprotkb:Q04207 intact:EBI-26672810|ensembl:ENSMUSP00000155584|uniprotkb:D5G1T0|uniprotkb:Q8BXP4|uniprotkb:Q8R1Z1 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:panky_mouse(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 33(gene name synonym)|uniprotkb:Ankrd33(gene name)|psi-mi:Ankrd33(display_short)|uniprotkb:Panky(gene name synonym) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672833|imex:IM-28774-2435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000047034(gene)|ensembl:ENSMUST00000229954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_659039.1|refseq:XP_006520750.1|entrezgene/locuslink:208258(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:koySBu0fUoWzUpOuplp/B1EvgXc10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:7iu9PV3+TSgkPwqdWRiUJ1Yyvyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:Q99NE9 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672802|imex:IM-28774-1087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rigid:JKlg1RrG3wgogWZL/x1Scfh1Eos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:O35317 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672764|imex:IM-28774-2841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rigid:OLKyev69YGI9W7N6Z7H4fAur9J0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:O35984 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-1373614|ensembl:ENSMUSP00000040464 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672756|imex:IM-28774-2839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rigid:Wvfj8HquYa5I/LzhZ/vAP4UqPPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:P41778 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672748|imex:IM-28774-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) - comment:mint comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rigid:1FGWsQsy762SqPnXfOe6w+nb/yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:P41778 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672740|imex:IM-28774-2003 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) - comment:mint comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rigid:1FGWsQsy762SqPnXfOe6w+nb/yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:P09632 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672732|imex:IM-28774-3257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:Dk10hy6R0gutCeDHeEqsb8fdPR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BG99 uniprotkb:P09092 intact:EBI-8457976|uniprotkb:Q8R4B0|intact:MINT-4110211|ensembl:ENSMUSP00000035806|ensembl:ENSMUSP00000079578|ensembl:ENSMUSP00000135581 intact:EBI-26668838|ensembl:ENSMUSP00000058755|uniprotkb:Q9JI98 psi-mi:pknx2_mouse(display_long)|uniprotkb:Pknox2(gene name)|psi-mi:Pknox2(display_short)|uniprotkb:Prep2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym) psi-mi:hxa6_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.2(gene name synonym)|uniprotkb:Homeobox protein M5-4(gene name synonym)|uniprotkb:Hoxa6(gene name)|psi-mi:Hoxa6(display_short)|uniprotkb:Hox-1.2(gene name synonym)|uniprotkb:Hoxa-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672724|imex:IM-28774-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683752.2|refseq:NP_001025009.1|refseq:XP_006510187.1|refseq:XP_006510188.1|refseq:XP_006510189.1|refseq:XP_006510190.1|refseq:XP_017168744.1|ensembl:ENSMUSG00000035934(gene)|ensembl:ENSMUST00000039674(transcript)|ensembl:ENSMUST00000080754(transcript)|ensembl:ENSMUST00000177218(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q8BG99|entrezgene/locuslink:208076(identity) ensembl:ENSMUSG00000043219(gene)|ensembl:ENSMUST00000062829(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_034584.1|entrezgene/locuslink:15403(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vYRs0VSBBXEDTNNiGkAyxwPRRyw10090 rogid:h4344WEVFSGp7m6UWPSAQn7hIVU10090 rigid:vg//Xs0oY6Bqud+0ZwPYYuhkOQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTN3 uniprotkb:Q04207 intact:EBI-5273743|uniprotkb:Q3U458|uniprotkb:Q3UDJ3|uniprotkb:Q5SRX5|uniprotkb:Q8C733|uniprotkb:Q99JK7|ensembl:ENSMUSP00000020846 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:srbp1_mouse(display_long)|uniprotkb:Srebf1(gene name)|psi-mi:Srebf1(display_short)|uniprotkb:Srebp1(gene name synonym)|uniprotkb:Sterol regulatory element-binding transcription factor 1(gene name synonym) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672716|imex:IM-28774-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035610.1|refseq:NP_001300908.1|refseq:XP_006532778.1|ensembl:ENSMUSG00000020538(gene)|ensembl:ENSMUST00000020846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010876"(lipid localization)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032094"(response to food)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-MMU-1655829|entrezgene/locuslink:20787(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:poshjAAi/h+PPSRMcBhjR0enVQA10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:JboPhCg7Ec3MXjgcXwBE2TCZg2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTN3 uniprotkb:Q61545 intact:EBI-5273743|uniprotkb:Q3U458|uniprotkb:Q3UDJ3|uniprotkb:Q5SRX5|uniprotkb:Q8C733|uniprotkb:Q99JK7|ensembl:ENSMUSP00000020846 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:srbp1_mouse(display_long)|uniprotkb:Srebf1(gene name)|psi-mi:Srebf1(display_short)|uniprotkb:Srebp1(gene name synonym)|uniprotkb:Sterol regulatory element-binding transcription factor 1(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672708|imex:IM-28774-1535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035610.1|refseq:NP_001300908.1|refseq:XP_006532778.1|ensembl:ENSMUSG00000020538(gene)|ensembl:ENSMUST00000020846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010876"(lipid localization)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032094"(response to food)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-MMU-1655829|entrezgene/locuslink:20787(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:poshjAAi/h+PPSRMcBhjR0enVQA10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:7Oe9nn46bpsc5pFNqY47+Pfep6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q9WTN3 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-5273743|uniprotkb:Q3U458|uniprotkb:Q3UDJ3|uniprotkb:Q5SRX5|uniprotkb:Q8C733|uniprotkb:Q99JK7|ensembl:ENSMUSP00000020846 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:srbp1_mouse(display_long)|uniprotkb:Srebf1(gene name)|psi-mi:Srebf1(display_short)|uniprotkb:Srebp1(gene name synonym)|uniprotkb:Sterol regulatory element-binding transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672700|imex:IM-28774-2001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) refseq:NP_035610.1|refseq:NP_001300908.1|refseq:XP_006532778.1|ensembl:ENSMUSG00000020538(gene)|ensembl:ENSMUST00000020846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010876"(lipid localization)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032094"(response to food)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033762"(response to glucagon)|go:"GO:0042493"|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051591"(response to cAMP)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-MMU-1655829|entrezgene/locuslink:20787(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:poshjAAi/h+PPSRMcBhjR0enVQA10090 rigid:mGWLfjo4VgElia4bzxlacz/iUR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40645 uniprotkb:Q61179 intact:EBI-3505685|uniprotkb:Q62250|uniprotkb:Q9QWS5|ensembl:ENSMUSP00000072583|ensembl:ENSMUSP00000129027 intact:EBI-646653|ensembl:ENSMUSP00000120359 psi-mi:sox6_mouse(display_long)|uniprotkb:Sox6(gene name)|psi-mi:Sox6(display_short)|uniprotkb:Sox-6(gene name synonym)|uniprotkb:SOX-LZ(gene name synonym) psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672692|imex:IM-28774-1533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240009.1|refseq:XP_011240013.1|refseq:NP_035575.1|ensembl:ENSMUSG00000051910(gene)|ensembl:ENSMUST00000072804(transcript)|ensembl:ENSMUST00000166207(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021529"(spinal cord oligodendrocyte cell differentiation)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051216"(cartilage development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR027153|interpro:IPR036910|reactome:R-MMU-3769402|refseq:NP_001264255.1|refseq:NP_001264257.1|entrezgene/locuslink:20679(identity) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/75ue2MRV87y9md6501iiDfVHJQ10090 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rigid:Zqc5wGh3MxQ2zazu70t9kHVMxxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63015 uniprotkb:P48432 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 intact:EBI-2313612 psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:sox2_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short)|uniprotkb:Sox-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672684|imex:IM-28774-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like)|entrezgene/locuslink:18508(identity) refseq:NP_035573.3|mint:P48432|dip:DIP-54522N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035198"(miRNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046148"(pigment biosynthetic process)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048839"(inner ear development)|go:"GO:0048852"(diencephalon morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050973"(detection of mechanical stimulus involved in equilibrioception)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0070848"(response to growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|rcsb pdb:1GT0|rcsb pdb:6HT5|reactome:R-MMU-3769402|go:"GO:0035019"(somatic stem cell population maintenance)|entrezgene/locuslink:20674(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 rogid:oO2sjv3/Iaj91kqGJ1L07+hhxVA10090 rigid:FRfSIXqnQB9x79kIuA+0fa22pRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48432 uniprotkb:O35137 intact:EBI-2313612 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:sox2_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short)|uniprotkb:Sox-2(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672660|imex:IM-28774-3255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|mint:P48432|dip:DIP-54522N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035198"(miRNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046148"(pigment biosynthetic process)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048839"(inner ear development)|go:"GO:0048852"(diencephalon morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050973"(detection of mechanical stimulus involved in equilibrioception)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0070848"(response to growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|rcsb pdb:1GT0|rcsb pdb:6HT5|reactome:R-MMU-3769402|go:"GO:0035019"(somatic stem cell population maintenance)|entrezgene/locuslink:20674(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oO2sjv3/Iaj91kqGJ1L07+hhxVA10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:ofkk0plkHD1dpBoS2iImpCZKR3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63015 uniprotkb:P48432 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 intact:EBI-2313612 psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:sox2_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short)|uniprotkb:Sox-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672676|imex:IM-28774-2837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like)|entrezgene/locuslink:18508(identity) refseq:NP_035573.3|mint:P48432|dip:DIP-54522N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035198"(miRNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046148"(pigment biosynthetic process)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048839"(inner ear development)|go:"GO:0048852"(diencephalon morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050973"(detection of mechanical stimulus involved in equilibrioception)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0070848"(response to growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|rcsb pdb:1GT0|rcsb pdb:6HT5|reactome:R-MMU-3769402|go:"GO:0035019"(somatic stem cell population maintenance)|entrezgene/locuslink:20674(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 rogid:oO2sjv3/Iaj91kqGJ1L07+hhxVA10090 rigid:FRfSIXqnQB9x79kIuA+0fa22pRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48432 uniprotkb:P81270 intact:EBI-2313612 intact:EBI-79647|ensembl:ENSMUSP00000156669|uniprotkb:Q8C5L4|uniprotkb:Q920K7|uniprotkb:Q920K8|uniprotkb:Q920K9|uniprotkb:A6H6E7 psi-mi:sox2_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short)|uniprotkb:Sox-2(gene name synonym) psi-mi:erg_mouse(display_long)|uniprotkb:Erg(gene name)|psi-mi:Erg(display_short)|uniprotkb:Erg-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672668|imex:IM-28774-1999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|mint:P48432|dip:DIP-54522N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035198"(miRNA binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046148"(pigment biosynthetic process)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048839"(inner ear development)|go:"GO:0048852"(diencephalon morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050973"(detection of mechanical stimulus involved in equilibrioception)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0070848"(response to growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|rcsb pdb:1GT0|rcsb pdb:6HT5|reactome:R-MMU-3769402|go:"GO:0035019"(somatic stem cell population maintenance)|entrezgene/locuslink:20674(identity) ensembl:ENSMUSG00000040732(gene)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|mint:P81270|ensembl:ENSMUST00000233881(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000418(Ets)|refseq:NP_598420.1|refseq:NP_001289081.1|refseq:NP_001289082.1|refseq:NP_001289083.1|refseq:NP_001289108.1|refseq:NP_001289112.1|refseq:XP_006522957.1|refseq:XP_006522958.1|refseq:XP_006522959.1|refseq:XP_006522962.1|refseq:XP_006522963.1|entrezgene/locuslink:13876(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oO2sjv3/Iaj91kqGJ1L07+hhxVA10090 rogid:Mz5YzYpYlL1FqkatSPYfrEiaAPo10090 rigid:rvwsUF7srTZdigsUrXX2UA90YQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22361 uniprotkb:Q04742 intact:EBI-5272860|uniprotkb:E9QP86|ensembl:ENSMUSP00000031535 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:hnf1a_mouse(display_long)|uniprotkb:Hnf1a(gene name)|psi-mi:Hnf1a(display_short)|uniprotkb:Hnf-1(gene name synonym)|uniprotkb:Hnf-1a(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:Liver-specific transcription factor LF-B1(gene name synonym)|uniprotkb:Transcription factor 1(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673190|imex:IM-28774-2005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033353.2|ensembl:ENSMUSG00000029556(gene)|ensembl:ENSMUST00000031535(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001824"(blastocyst development)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008104"(protein localization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016573"(histone acetylation)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035623"(renal glucose absorption)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045453"(bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048608"(reproductive structure development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006898(Hepatocyte nuclear factor 1, alpha isoform C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P22361|rcsb pdb:1F93|rcsb pdb:1G2Y|rcsb pdb:1G2Z|rcsb pdb:1G39|rcsb pdb:1JB6|go:"GO:0045120"(pronucleus)|entrezgene/locuslink:21405(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RU8cTEgDUX13LBGIHa7hxUIkojc10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:TqFzvQOMRJkaeqBl5ZUH4rpV1cE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:P22361 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-5272860|uniprotkb:E9QP86|ensembl:ENSMUSP00000031535 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:hnf1a_mouse(display_long)|uniprotkb:Hnf1a(gene name)|psi-mi:Hnf1a(display_short)|uniprotkb:Hnf-1(gene name synonym)|uniprotkb:Hnf-1a(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:Liver-specific transcription factor LF-B1(gene name synonym)|uniprotkb:Transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673182|imex:IM-28774-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) refseq:NP_033353.2|ensembl:ENSMUSG00000029556(gene)|ensembl:ENSMUST00000031535(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001824"(blastocyst development)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008104"(protein localization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016573"(histone acetylation)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035623"(renal glucose absorption)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045453"(bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048608"(reproductive structure development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006898(Hepatocyte nuclear factor 1, alpha isoform C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P22361|rcsb pdb:1F93|rcsb pdb:1G2Y|rcsb pdb:1G2Z|rcsb pdb:1G39|rcsb pdb:1JB6|go:"GO:0045120"(pronucleus)|entrezgene/locuslink:21405(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:RU8cTEgDUX13LBGIHa7hxUIkojc10090 rigid:dkExJJ9M1lZ3M2EHZfzNtVH4fbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:P22361 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-5272860|uniprotkb:E9QP86|ensembl:ENSMUSP00000031535 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:hnf1a_mouse(display_long)|uniprotkb:Hnf1a(gene name)|psi-mi:Hnf1a(display_short)|uniprotkb:Hnf-1(gene name synonym)|uniprotkb:Hnf-1a(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:Liver-specific transcription factor LF-B1(gene name synonym)|uniprotkb:Transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673174|imex:IM-28774-3261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) refseq:NP_033353.2|ensembl:ENSMUSG00000029556(gene)|ensembl:ENSMUST00000031535(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001824"(blastocyst development)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008104"(protein localization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016573"(histone acetylation)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035623"(renal glucose absorption)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045453"(bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048608"(reproductive structure development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006898(Hepatocyte nuclear factor 1, alpha isoform C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P22361|rcsb pdb:1F93|rcsb pdb:1G2Y|rcsb pdb:1G2Z|rcsb pdb:1G39|rcsb pdb:1JB6|go:"GO:0045120"(pronucleus)|entrezgene/locuslink:21405(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:RU8cTEgDUX13LBGIHa7hxUIkojc10090 rigid:dkExJJ9M1lZ3M2EHZfzNtVH4fbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70325 uniprotkb:Q05BA5 intact:EBI-26673135|ensembl:ENSMUSP00000000096|ensembl:ENSMUSP00000103682|uniprotkb:B1AQT9|uniprotkb:Q8R5F6 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:tbx4_mouse(display_long)|uniprotkb:Tbx4(gene name)|psi-mi:Tbx4(display_short) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673166|imex:IM-28774-1093 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000000094(gene)|ensembl:ENSMUST00000000096(transcript)|ensembl:ENSMUST00000108047(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990401"(embryonic lung development)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_035666.2|refseq:XP_006532843.1|entrezgene/locuslink:21387(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kCvkTvaQNE0RHsOP4cfZXO2Trl810090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:lMEVBF2vOKQhO/FieM01Riy6Bm4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62282 uniprotkb:Q61909 intact:EBI-26666949|ensembl:ENSMUSP00000030124 intact:EBI-309458|ensembl:ENSMUSP00000095856 psi-mi:tal2_mouse(display_long)|uniprotkb:Tal2(gene name)|psi-mi:Tal2(display_short) psi-mi:mtg8_mouse(display_long)|uniprotkb:Runx1t1(gene name)|psi-mi:Runx1t1(display_short)|uniprotkb:Cbfa2t1h(gene name synonym)|uniprotkb:Mtg8(gene name synonym)|uniprotkb:Cbfa2t1(gene name synonym)|uniprotkb:Protein MTG8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673127|imex:IM-28774-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028417(gene)|ensembl:ENSMUST00000030124(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|refseq:NP_033343.1|entrezgene/locuslink:21350(identity) refseq:NP_033952.1|ensembl:ENSMUSG00000006586(gene)|ensembl:ENSMUST00000098256(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|entrezgene/locuslink:12395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tDWYKvhprGUoqYYZRC7pdjc2I/E10090 rogid:uqmGKiiQLyU9z19R6hsnr1I97lo10090 rigid:u1wq83CCvcKjYO8IIWJtQXShBRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8C7B8 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26673088|ensembl:ENSMUSP00000040078|uniprotkb:Q8BPN9 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:zswm4_mouse(display_long)|uniprotkb:Zswim4(gene name)|psi-mi:Zswim4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673119|imex:IM-28774-2443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000035671(gene)|ensembl:ENSMUST00000039480(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR007527(Zinc finger, SWIM-type)|refseq:NP_766091.2|entrezgene/locuslink:212168(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:RkRkScsaRBPtD5FjSOBpBdu2DM010090 rigid:4X/Xg60uh5v/9w+oJRyOj74/RfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C7B8 uniprotkb:Q61545 intact:EBI-26673088|ensembl:ENSMUSP00000040078|uniprotkb:Q8BPN9 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zswm4_mouse(display_long)|uniprotkb:Zswim4(gene name)|psi-mi:Zswim4(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673102|imex:IM-28774-1091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035671(gene)|ensembl:ENSMUST00000039480(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR007527(Zinc finger, SWIM-type)|refseq:NP_766091.2|entrezgene/locuslink:212168(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RkRkScsaRBPtD5FjSOBpBdu2DM010090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:44ufBWzgXimQLVeBznEQJOqxBow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0A087WPU8 uniprotkb:Q8CGW9 intact:EBI-26673036|ensembl:ENSMUSP00000139926 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 psi-mi:a0a087wpu8_mouse(display_long)|uniprotkb:Tfdp2(gene name)|psi-mi:Tfdp2(display_short) psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673080|imex:IM-28774-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032411(gene)|ensembl:ENSMUST00000188750(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|refseq:XP_006511025.1|entrezgene/locuslink:211586(identity) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oe+23BW7WmwtrF524SSLaWSgKNI10090 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rigid:svn7eLiF5pa2Bz2YYfEi+C0u86M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0A087WPU8 uniprotkb:O55144 intact:EBI-26673036|ensembl:ENSMUSP00000139926 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:a0a087wpu8_mouse(display_long)|uniprotkb:Tfdp2(gene name)|psi-mi:Tfdp2(display_short) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673072|imex:IM-28774-1089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032411(gene)|ensembl:ENSMUST00000188750(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|refseq:XP_006511025.1|entrezgene/locuslink:211586(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oe+23BW7WmwtrF524SSLaWSgKNI10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:EdY2bNko4XKPnBmTpARdfVqhFBo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0A087WPU8 uniprotkb:G3X904 intact:EBI-26673036|ensembl:ENSMUSP00000139926 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:a0a087wpu8_mouse(display_long)|uniprotkb:Tfdp2(gene name)|psi-mi:Tfdp2(display_short) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673064|imex:IM-28774-3259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032411(gene)|ensembl:ENSMUST00000188750(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|refseq:XP_006511025.1|entrezgene/locuslink:211586(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oe+23BW7WmwtrF524SSLaWSgKNI10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:pDOwwtLn1gYXab3sAGgyMudzAwo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0A087WPU8 uniprotkb:Q61501 intact:EBI-26673036|ensembl:ENSMUSP00000139926 intact:EBI-1025536|uniprotkb:Q80VZ3|ensembl:ENSMUSP00000099434 psi-mi:a0a087wpu8_mouse(display_long)|uniprotkb:Tfdp2(gene name)|psi-mi:Tfdp2(display_short) psi-mi:e2f1_mouse(display_long)|uniprotkb:E2f1(gene name)|psi-mi:E2f1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673056|imex:IM-28774-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032411(gene)|ensembl:ENSMUST00000188750(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|refseq:XP_006511025.1|entrezgene/locuslink:211586(identity) refseq:NP_031917.1|ensembl:ENSMUSG00000027490(gene)|ensembl:ENSMUST00000103145(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q61501|reactome:R-MMU-68689|reactome:R-MMU-68911|reactome:R-MMU-69231|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:13555(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oe+23BW7WmwtrF524SSLaWSgKNI10090 rogid:VKWBpWoL5IidTXCB/p8nK+TgQ1A10090 rigid:THXhZTXF1s9gR0na5JtTJ2PnBJM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6NZI9 uniprotkb:Q61545 intact:EBI-26673007|ensembl:ENSMUSP00000064611 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:q6nzi9_mouse(display_long)|uniprotkb:Zfp180(gene name)|psi-mi:Zfp180(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673028|imex:IM-28774-2441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000057101(gene)|ensembl:ENSMUST00000068975(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_001038951.1|refseq:NP_001276563.1|refseq:NP_001276566.1|refseq:NP_001276569.1|refseq:NP_001276570.1|entrezgene/locuslink:210135(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hChMx4K1tEOFDbwRLVBT/ojWhOo10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:kznXUm2xpp5jZBEx1/Pz2LSJIsw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VD76 uniprotkb:Q9JIB4 intact:EBI-26672957|ensembl:ENSMUSP00000031333 intact:EBI-6260800|ensembl:ENSMUSP00000065228 psi-mi:tf2h3_mouse(display_long)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym)|uniprotkb:Gtf2h3(gene name)|psi-mi:Gtf2h3(display_short) psi-mi:tf2h2_mouse(display_long)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:Btf2p44(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Gtf2h2(gene name)|psi-mi:Gtf2h2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672999|imex:IM-28774-2843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029387(gene)|ensembl:ENSMUST00000031333(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|go:"GO:0005675"(transcription factor TFIIH holo complex)|refseq:NP_852075.1|entrezgene/locuslink:209357(identity) ensembl:ENSMUST00000066984(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|ensembl:ENSMUSG00000021639(gene)|refseq:NP_071294.3|entrezgene/locuslink:23894(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:03J7ZzTe8u/UGld855lyyrKPJKk10090 rogid:B1sNNBPY99dly+ZymdKJeaj6nWA10090 rigid:/GWG/Gbp7exRW6aDBEbUEHHhSO8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55201 uniprotkb:P63271 intact:EBI-8321883|intact:MINT-4105191|uniprotkb:Q3UJH1|uniprotkb:Q3UJ77|uniprotkb:Q3UKD7|uniprotkb:Q6PFR4|uniprotkb:Q6PB73|uniprotkb:Q6PDP0|uniprotkb:Q3UM54|ensembl:ENSMUSP00000003527|ensembl:ENSMUSP00000147164 intact:EBI-26672899|ensembl:ENSMUSP00000091487|uniprotkb:B2KGH6|uniprotkb:Q16550|uniprotkb:Q3TIA2|uniprotkb:Q5NCP8|uniprotkb:Q5NCP9|uniprotkb:Q5NCQ0|uniprotkb:Q62387 psi-mi:spt5h_mouse(display_long)|uniprotkb:Supt5h(gene name)|psi-mi:Supt5h(display_short)|uniprotkb:Supt5(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym) psi-mi:spt4a_mouse(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit 1(gene name synonym)|uniprotkb:Transcription elongation factor SPT4 1(gene name synonym)|uniprotkb:Supt4h1a(gene name)|psi-mi:Supt4h1a(display_short)|uniprotkb:Spt4h(gene name synonym)|uniprotkb:Supt4a(gene name synonym)|uniprotkb:Supt4h(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672949|imex:IM-28774-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038704.1|ensembl:ENSMUSG00000003435(gene)|ensembl:ENSMUST00000003527(transcript)|ensembl:ENSMUST00000209141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O55201|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-75955|reactome:R-MMU-77075|entrezgene/locuslink:20924(identity) ensembl:ENSMUSG00000020485(gene)|ensembl:ENSMUST00000093955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|refseq:NP_033322.1|entrezgene/locuslink:20922(identity) - comment:mint|function:"Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YOFTk5cUKQNJ/ApjpLqduHjivOI10090 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE10090 rigid:YdLinQElsnU9cwr6Aia3V96Osu0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63271 uniprotkb:Q07279 intact:EBI-26672899|ensembl:ENSMUSP00000091487|uniprotkb:B2KGH6|uniprotkb:Q16550|uniprotkb:Q3TIA2|uniprotkb:Q5NCP8|uniprotkb:Q5NCP9|uniprotkb:Q5NCQ0|uniprotkb:Q62387 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:spt4a_mouse(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit 1(gene name synonym)|uniprotkb:Transcription elongation factor SPT4 1(gene name synonym)|uniprotkb:Supt4h1a(gene name)|psi-mi:Supt4h1a(display_short)|uniprotkb:Spt4h(gene name synonym)|uniprotkb:Supt4a(gene name synonym)|uniprotkb:Supt4h(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672941|imex:IM-28774-2439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020485(gene)|ensembl:ENSMUST00000093955(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|refseq:NP_033322.1|entrezgene/locuslink:20922(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:gIfGgCRlSOl9WC0EbCkcRCxEm8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QXJ2 uniprotkb:Q61179 intact:EBI-646643|ensembl:ENSMUSP00000082855 intact:EBI-646653|ensembl:ENSMUSP00000120359 psi-mi:q9qxj2_mouse(display_long)|uniprotkb:Stat2(gene name)|psi-mi:Stat2(display_short) psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26672875|imex:IM-28774-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064347.1|ensembl:ENSMUSG00000040033(gene)|ensembl:ENSMUST00000085708(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|entrezgene/locuslink:20847(identity) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rqLwSu56f3fYSQdaEITgDU0mT9010090 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rigid:GFChxDWvYbBnzQ5GgTqeUn2w0+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:P97367 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673340|imex:IM-28774-1101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:O9MHfC3Ncw+eFwI/MgrHQn9qFUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:O88522 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673332|imex:IM-28774-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:TCzHKKQa0Qx6aBsLAXkbU8IhuIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60899 uniprotkb:P15806 intact:EBI-8329853|intact:MINT-4094224|ensembl:ENSMUSP00000008633 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:elav2_mouse(display_long)|uniprotkb:Elavl2(gene name)|psi-mi:Elavl2(display_short)|uniprotkb:Hub(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)|uniprotkb:ELAV-like neuronal protein 1(gene name synonym)|uniprotkb:Nervous system-specific RNA-binding protein Mel-N1(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673324|imex:IM-28774-2009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034616.1|refseq:XP_006502852.1|refseq:XP_006502853.1|refseq:XP_006502854.1|ensembl:ENSMUSG00000008489(gene)|ensembl:ENSMUST00000008633(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0045202"(synapse)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034914|interpro:IPR034999|interpro:IPR035979|mint:Q60899|reactome:R-MMU-72163|entrezgene/locuslink:15569(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - comment:mint|function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dgDCiu1mN8mz6K95+ihBGQY8K8k10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:H7QYpS7HDiatC/35XIViFnLVqtE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:Q9Z2S7 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-15771128|ensembl:ENSMUSP00000062589|uniprotkb:B1AVF3|uniprotkb:C6EX03|uniprotkb:Q3UNI6|uniprotkb:Q8K160|uniprotkb:Q9EQN0|uniprotkb:Q9EQN1|uniprotkb:Q9EQN2 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:t22d3_mouse(display_long)|uniprotkb:Tsc22d3(gene name)|psi-mi:Tsc22d3(display_short)|uniprotkb:Dsip1(gene name synonym)|uniprotkb:Dsipi(gene name synonym)|uniprotkb:Gilz(gene name synonym)|uniprotkb:Glucocorticoid-induced leucine zipper protein(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673316|imex:IM-28774-3265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) ensembl:ENSMUSG00000031431(gene)|ensembl:ENSMUST00000055738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|interpro:IPR000580(TSC-22 / Dip / Bun)|reactome:R-MMU-2672351|refseq:NP_001070832.1|refseq:NP_034416.3|refseq:XP_006528562.1|refseq:XP_006528563.1|refseq:XP_006528564.1|refseq:XP_006528566.1|refseq:XP_006528567.1|refseq:XP_006528568.1|dip:DIP-48844N|entrezgene/locuslink:14605(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:dL2mVYP+cp0QGH7QZuxZ5vWhWJI10090 rigid:odD1Anu/FDriZMnN+mUjWub3PC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70338 uniprotkb:P15806 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673308|imex:IM-28774-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1|entrezgene/locuslink:14581(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:n2jNfYT9oivnIT+XVYh0YC0eTOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:P79621 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673300|imex:IM-28774-1099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:zFFt46NJdC572DvJNBge/nTkKbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22361 uniprotkb:D3Z4R4 intact:EBI-5272860|uniprotkb:E9QP86|ensembl:ENSMUSP00000031535 intact:EBI-26673198|ensembl:ENSMUSP00000095588|ensembl:ENSMUSP00000101701 psi-mi:hnf1a_mouse(display_long)|uniprotkb:Hnf1a(gene name)|psi-mi:Hnf1a(display_short)|uniprotkb:Hnf-1(gene name synonym)|uniprotkb:Hnf-1a(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:Liver-specific transcription factor LF-B1(gene name synonym)|uniprotkb:Transcription factor 1(gene name synonym) psi-mi:d3z4r4_mouse(display_long)|uniprotkb:Nkx6-2(gene name)|psi-mi:Nkx6-2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673236|imex:IM-28774-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033353.2|ensembl:ENSMUSG00000029556(gene)|ensembl:ENSMUST00000031535(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001824"(blastocyst development)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008104"(protein localization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016573"(histone acetylation)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035623"(renal glucose absorption)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045453"(bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048608"(reproductive structure development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006898(Hepatocyte nuclear factor 1, alpha isoform C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P22361|rcsb pdb:1F93|rcsb pdb:1G2Y|rcsb pdb:1G2Z|rcsb pdb:1G39|rcsb pdb:1JB6|go:"GO:0045120"(pronucleus)|entrezgene/locuslink:21405(identity) ensembl:ENSMUSG00000041309(gene)|ensembl:ENSMUST00000097974(transcript)|ensembl:ENSMUST00000106095(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010455"(positive regulation of cell fate commitment)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031641"(regulation of myelination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_899071.2|entrezgene/locuslink:14912(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RU8cTEgDUX13LBGIHa7hxUIkojc10090 rogid:8uwDwWnjt2gFmwB282nVs56MH/I10090 rigid:SYXWR4eylNCjKQg3GCIT6gnipG4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60722 uniprotkb:P41133 intact:EBI-310070|uniprotkb:Q60721|uniprotkb:Q62211|uniprotkb:Q64072|uniprotkb:Q80UE8|ensembl:ENSMUSP00000077577|ensembl:ENSMUSP00000110631|ensembl:ENSMUSP00000110636 intact:EBI-309448|ensembl:ENSMUSP00000008016 psi-mi:itf2_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)|uniprotkb:Itf2(gene name synonym)|uniprotkb:Sef2(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:Class A helix-loop-helix transcription factor ME2(gene name synonym) psi-mi:id3_mouse(display_long)|uniprotkb:Id3(gene name)|psi-mi:Id3(display_short)|uniprotkb:Hlh462(gene name synonym)|uniprotkb:Id-3(gene name synonym)|uniprotkb:Idb3(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 462(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673284|imex:IM-28774-1097 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077436.1|refseq:NP_038713.1|refseq:XP_006525809.1|refseq:XP_006525810.1|refseq:XP_006525813.1|refseq:XP_006525825.1|ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000078486(transcript)|ensembl:ENSMUST00000114980(transcript)|ensembl:ENSMUST00000114985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070888"(E-box binding)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:Q60722|reactome:R-MMU-525793|go:"GO:0016525"(negative regulation of angiogenesis)|refseq:XP_017173346.1|dip:DIP-42841N|entrezgene/locuslink:21413(identity) refseq:NP_032347.1|ensembl:ENSMUSG00000007872(gene)|ensembl:ENSMUST00000008016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15903(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:o8X4UFFW9S6TNL/Ur0E/WC+b/8010090 rogid:wRsCFFWeh4NnuA3HwTmiVahLDtI10090 rigid:JaoX3z7MVWP8MtyCnQ5LMLUjvoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60722 uniprotkb:Q6GTZ3 intact:EBI-310070|uniprotkb:Q60721|uniprotkb:Q62211|uniprotkb:Q64072|uniprotkb:Q80UE8|ensembl:ENSMUSP00000077577|ensembl:ENSMUSP00000110631|ensembl:ENSMUSP00000110636 intact:EBI-26669132 psi-mi:itf2_mouse(display_long)|uniprotkb:Tcf4(gene name)|psi-mi:Tcf4(display_short)|uniprotkb:Itf2(gene name synonym)|uniprotkb:Sef2(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:Class A helix-loop-helix transcription factor ME2(gene name synonym) psi-mi:q6gtz3_mouse(display_long)|uniprotkb:Id1(gene name)|psi-mi:Id1(display_short)|uniprotkb:Idb1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673276|imex:IM-28774-2007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077436.1|refseq:NP_038713.1|refseq:XP_006525809.1|refseq:XP_006525810.1|refseq:XP_006525813.1|refseq:XP_006525825.1|ensembl:ENSMUSG00000053477(gene)|ensembl:ENSMUST00000078486(transcript)|ensembl:ENSMUST00000114980(transcript)|ensembl:ENSMUST00000114985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070888"(E-box binding)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:Q60722|reactome:R-MMU-525793|go:"GO:0016525"(negative regulation of angiogenesis)|refseq:XP_017173346.1|dip:DIP-42841N|entrezgene/locuslink:21413(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_034625.1|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15901(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:o8X4UFFW9S6TNL/Ur0E/WC+b/8010090 rogid:IRUXStmLzIzQ5jb8Aw8r0MhfKPc10090 rigid:tIYfE5wPqNFb0P7be80sInK5lS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35437 uniprotkb:O35317 intact:EBI-309880|uniprotkb:Q3U023|ensembl:ENSMUSP00000053178 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 psi-mi:tcf21_mouse(display_long)|uniprotkb:Tcf21(gene name)|psi-mi:Tcf21(display_short)|uniprotkb:Pod1(gene name synonym)|uniprotkb:Podocyte-expressed 1(gene name synonym)|uniprotkb:Epicardin(gene name synonym)|uniprotkb:Capsulin(gene name synonym) psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673268|imex:IM-28774-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035675.1|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072277"(metanephric glomerular capillary formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060426"(lung vasculature development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060539"(diaphragm development)|go:"GO:0060541"(respiratory system development)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070888"(E-box binding)|ensembl:ENSMUSG00000045680(gene)|ensembl:ENSMUST00000049930(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0032502"(developmental process)|go:"GO:0032835"(glomerulus development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048536"(spleen development)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|entrezgene/locuslink:21412(identity) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sJIobeKTiwgo9cvpif4o9j996A010090 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rigid:iZiOvXJh54cnKDI4BcN0MDBBWyQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:O35437 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-309880|uniprotkb:Q3U023|ensembl:ENSMUSP00000053178 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:tcf21_mouse(display_long)|uniprotkb:Tcf21(gene name)|psi-mi:Tcf21(display_short)|uniprotkb:Pod1(gene name synonym)|uniprotkb:Podocyte-expressed 1(gene name synonym)|uniprotkb:Epicardin(gene name synonym)|uniprotkb:Capsulin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673260|imex:IM-28774-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) refseq:NP_035675.1|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072277"(metanephric glomerular capillary formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060426"(lung vasculature development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060539"(diaphragm development)|go:"GO:0060541"(respiratory system development)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070888"(E-box binding)|ensembl:ENSMUSG00000045680(gene)|ensembl:ENSMUST00000049930(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0032502"(developmental process)|go:"GO:0032835"(glomerulus development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048536"(spleen development)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|entrezgene/locuslink:21412(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:sJIobeKTiwgo9cvpif4o9j996A010090 rigid:Yg1+eQyj+c0OL3NR1jz4jsara9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27889 uniprotkb:P61458 intact:EBI-8373125|intact:MINT-4097641|uniprotkb:Q9WTL6|uniprotkb:Q9R1W2|uniprotkb:Q5NC37|uniprotkb:Q9WTL5|uniprotkb:Q9CS26|uniprotkb:Q8R162|uniprotkb:Q9R1W1|ensembl:ENSMUSP00000021016 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:hnf1b_mouse(display_long)|uniprotkb:Hnf-1b(gene name synonym)|uniprotkb:Hnf1b(gene name)|psi-mi:Hnf1b(display_short)|uniprotkb:Tcf2(gene name synonym)|uniprotkb:Transcription factor 2(gene name synonym)|uniprotkb:Homeoprotein LFB3(gene name synonym) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673252|imex:IM-28774-1095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033356.2|refseq:XP_006532859.1|refseq:NP_001278197.1|refseq:NP_001278198.1|ensembl:ENSMUSG00000020679(gene)|ensembl:ENSMUST00000021016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001822"(kidney development)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007492"(endoderm development)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035565"(regulation of pronephros size)|go:"GO:0039020"(pronephric nephron tubule development)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048793"(pronephros development)|go:"GO:0048806"(genitalia development)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060429"(epithelium development)|go:"GO:0060677"(ureteric bud elongation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061017"(hepatoblast differentiation)|go:"GO:0061296"(negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072095"(regulation of branch elongation involved in ureteric bud branching)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072176"(nephric duct development)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072181"(mesonephric duct formation)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P27889|entrezgene/locuslink:21410(identity) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) - function:Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'|comment:mint function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:714+z3cTzNeHm1dr/Tqky7SRZ9U10090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rigid:/EwYlmKPcqyOu7n3X5PezqukXuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27889 uniprotkb:P61458 intact:EBI-8373125|intact:MINT-4097641|uniprotkb:Q9WTL6|uniprotkb:Q9R1W2|uniprotkb:Q5NC37|uniprotkb:Q9WTL5|uniprotkb:Q9CS26|uniprotkb:Q8R162|uniprotkb:Q9R1W1|ensembl:ENSMUSP00000021016 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:hnf1b_mouse(display_long)|uniprotkb:Hnf-1b(gene name synonym)|uniprotkb:Hnf1b(gene name)|psi-mi:Hnf1b(display_short)|uniprotkb:Tcf2(gene name synonym)|uniprotkb:Transcription factor 2(gene name synonym)|uniprotkb:Homeoprotein LFB3(gene name synonym) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673244|imex:IM-28774-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033356.2|refseq:XP_006532859.1|refseq:NP_001278197.1|refseq:NP_001278198.1|ensembl:ENSMUSG00000020679(gene)|ensembl:ENSMUST00000021016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001706"(endoderm formation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001822"(kidney development)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007492"(endoderm development)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035565"(regulation of pronephros size)|go:"GO:0039020"(pronephric nephron tubule development)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048793"(pronephros development)|go:"GO:0048806"(genitalia development)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060429"(epithelium development)|go:"GO:0060677"(ureteric bud elongation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061017"(hepatoblast differentiation)|go:"GO:0061296"(negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072095"(regulation of branch elongation involved in ureteric bud branching)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072176"(nephric duct development)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072181"(mesonephric duct formation)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P27889|entrezgene/locuslink:21410(identity) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) - function:Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'|comment:mint function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:714+z3cTzNeHm1dr/Tqky7SRZ9U10090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rigid:/EwYlmKPcqyOu7n3X5PezqukXuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:P48754 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-6876136|ensembl:ENSMUSP00000017290|uniprotkb:A2A4Q4|uniprotkb:Q60957|uniprotkb:Q60983 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:brca1_mouse(display_long)|uniprotkb:Brca1(gene name)|psi-mi:Brca1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673292|imex:IM-28774-3263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|reactome:R-MMU-3108214|ensembl:ENSMUSG00000017146(gene)|ensembl:ENSMUST00000017290(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|refseq:NP_033894.3|dip:DIP-41981N|entrezgene/locuslink:12189(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:n930/noKAvHtITiW9/qUMSxbiT410090 rigid:bQnXuAxBG66HdTgKAm40gbwVy3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q3U4B1 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673645|imex:IM-28774-2013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:aD7xaRfF2+qMYahTT5OU/s/ybIg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:G3UW74 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-5745202|ensembl:ENSMUSP00000129375 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673637|imex:IM-28774-3271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rigid:DJ3St3RD0QMc5aAUMz24YWeWsv4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VE28 uniprotkb:G3UW74 intact:EBI-1538490|uniprotkb:Q3TYU5|uniprotkb:Q3UM34|uniprotkb:Q8C4J8|uniprotkb:Q91Y45|uniprotkb:Q9D7U9|ensembl:ENSMUSP00000022051 intact:EBI-5745202|ensembl:ENSMUSP00000129375 psi-mi:nkd2_mouse(display_long)|uniprotkb:Nkd2(gene name)|psi-mi:Nkd2(display_short) psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673629|imex:IM-28774-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082462.3|refseq:NP_001334464.1|ensembl:ENSMUSG00000021567(gene)|ensembl:ENSMUST00000022051(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140|entrezgene/locuslink:72293(identity) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YahIfIwWuxWNCTmkeFs9nSf8UWc10090 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rigid:UlvvFUmSWb0H9oHDM7uJNgY0Wwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q9WUI0 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673621|imex:IM-28774-2845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rigid:soz5uEDrvg6QXEr3cED3eWgaqOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:A2AQR4 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-26673603|ensembl:ENSMUSP00000085285 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:a2aqr4_mouse(display_long)|uniprotkb:Zfp64(gene name)|psi-mi:Zfp64(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673613|imex:IM-28774-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) ensembl:ENSMUSG00000027551(gene)|ensembl:ENSMUST00000087971(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_033590.2|entrezgene/locuslink:22722(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:zzFaR9hgXdPiH+QNw8QFmUi0A9s10090 rigid:CHHwRJktDrYenbuNVzsc8Rn1ydI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q9JJP2 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-1770138|intact:EBI-1770168|uniprotkb:B1AX89|uniprotkb:B1AX90|uniprotkb:Q3UT91|uniprotkb:Q9CU77|uniprotkb:Q9JJP1|uniprotkb:Q9WUJ0|ensembl:ENSMUSP00000101269 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:p73_mouse(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673595|imex:IM-28774-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) refseq:NP_001119802.1|refseq:NP_001119803.1|refseq:NP_035772.2|dip:DIP-41942N|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030054"(cell junction)|go:"GO:0030900"(forebrain development)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:Q9JJP2|reactome:R-MMU-6804759|reactome:R-MMU-8939236|entrezgene/locuslink:22062(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090 rigid:NrNIgqUBE5zrgmgtEEhnnHnn1vc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:P02340 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-474016|uniprotkb:Q9QUP3|ensembl:ENSMUSP00000104298 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:p53_mouse(display_long)|uniprotkb:Tp53(gene name)|psi-mi:Tp53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Trp53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673587|imex:IM-28774-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) ensembl:ENSMUSG00000059552(gene)|ensembl:ENSMUST00000108658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|mint:P02340|rcsb pdb:1HU8|rcsb pdb:2GEQ|rcsb pdb:2IOI|rcsb pdb:2IOM|rcsb pdb:2IOO|rcsb pdb:2P52|rcsb pdb:3EXJ|rcsb pdb:3EXL|reactome:R-MMU-2559580|reactome:R-MMU-2559584|reactome:R-MMU-2559585|reactome:R-MMU-2559586|reactome:R-MMU-349425|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-5693565|reactome:R-MMU-6804754|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804758|reactome:R-MMU-6804759|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-69473|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-69895|reactome:R-MMU-8852276|reactome:R-MMU-8941855|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007569"(cell aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009411"(response to UV)|go:"GO:0009651"(response to salt stress)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010038"(response to metal ion)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033552"(response to vitamin B3)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043200"(response to amino acid)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045471"(response to ethanol)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051276"(chromosome organization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0034644"(cellular response to UV)|refseq:NP_001120705.1|refseq:NP_035770.2|refseq:XP_006533220.1|dip:DIP-369N|entrezgene/locuslink:22059(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:ZU1071LBVm95uqzi6RBNluw8wFo10090 rigid:ib/O9yz65gL+WBQGRMCYuQ/hDI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q60769 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-646595|uniprotkb:Q3U968|ensembl:ENSMUSP00000019997|ensembl:ENSMUSP00000101167 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:tnap3_mouse(display_long)|uniprotkb:Putative DNA-binding protein A20(gene name synonym)|uniprotkb:Zinc finger protein A20(gene name synonym)|uniprotkb:Tnfaip3(gene name)|psi-mi:Tnfaip3(display_short)|uniprotkb:Tnfip3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673579|imex:IM-28774-1107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) refseq:NP_033423.3|dip:DIP-41120N|refseq:XP_006512765.1|ensembl:ENSMUSG00000019850(gene)|ensembl:ENSMUST00000019997(transcript)|ensembl:ENSMUST00000105527(transcript)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002632"(negative regulation of granuloma formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019900"(kinase binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034148"(negative regulation of toll-like receptor 5 signaling pathway)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070429"(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0072573"(tolerance induction to lipopolysaccharide)|go:"GO:0072666"(establishment of protein localization to vacuole)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1990168"(protein K33-linked deubiquitination)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR033478|mint:Q60769|rcsb pdb:5DQ6|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689896|reactome:R-MMU-936440|entrezgene/locuslink:21929(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:hFNjd3fxx9grjtEq3kAdU0fiFh010090 rigid:RuwkjzbOYS/IEffQetVs0kNnD3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:P15806 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673571|imex:IM-28774-3269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:jPJqbEQBHU+guQavRQf1y5eHdgg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q60953 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673563|imex:IM-28774-2011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:YPN3LLNkl4IHoaWSTpYukoXaR4I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:O54943 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-1266779|uniprotkb:O54954 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673555|imex:IM-28774-1543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rigid:HxfKzG21vDoqqWAE9FEidLQ/xAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:P97489 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-26673507|ensembl:ENSMUSP00000015771|uniprotkb:Q3UQR0 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:gata5_mouse(display_long)|uniprotkb:GATA-binding factor 5(gene name synonym)|uniprotkb:Gata5(gene name)|psi-mi:Gata5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673547|imex:IM-28774-2445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) ensembl:ENSMUSG00000015627(gene)|ensembl:ENSMUST00000015771(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003274"(endocardial cushion fusion)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0062000"(positive regulation of cardiac endothelial to mesenchymal transition)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|reactome:R-MMU-983231|refseq:NP_032119.2|refseq:XP_006500617.1|entrezgene/locuslink:14464(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:7Q0sDjuro6dsfi8e2XYl3jVIsFc10090 rigid:/2XmvTl7umPZXjCqof8PpdSRcFs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q61545 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673499|imex:IM-28774-3267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:gphDLjYrE9esxOb8UPdu2b20/MQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:O35137 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673491|imex:IM-28774-1541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:1GUgYkVXGCha2Y+dnE70X1i3Q90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15910 uniprotkb:Q01844 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673483|imex:IM-28774-1105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|entrezgene/locuslink:2146(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:Cy97/t3hs8kannYg3+xjHc9QBhY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VIM5 uniprotkb:Q9D738 intact:EBI-16354401|ensembl:ENSMUSP00000099695|uniprotkb:Q5SS65|uniprotkb:Q6W8X1|uniprotkb:Q8C3W6|uniprotkb:Q8VIL4 intact:EBI-26673456|ensembl:ENSMUSP00000033549 psi-mi:mycd_mouse(display_long)|uniprotkb:Myocd(gene name)|psi-mi:Myocd(display_short)|uniprotkb:Basic SAP coiled-coil transcription activator 2(gene name synonym)|uniprotkb:Bsac2(gene name synonym)|uniprotkb:Mycd(gene name synonym)|uniprotkb:SRF cofactor protein(gene name synonym)|uniprotkb:Srfcp(gene name synonym) psi-mi:asb12_mouse(display_long)|uniprotkb:Asb12(gene name)|psi-mi:Asb12(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673475|imex:IM-28774-1539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020542(gene)|ensembl:ENSMUST00000102635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0000785"(chromatin)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043954"(cellular component maintenance)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048565"(digestive tract development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060065"(uterus development)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070514"(SRF-myogenin-E12 complex)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900239"(regulation of phenotypic switching)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000721"(positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|go:"GO:2000724"(positive regulation of cardiac vascular smooth muscle cell differentiation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR028721|interpro:IPR036361|interpro:IPR043451|dip:DIP-29754N|refseq:NP_660118.3|refseq:NP_666498.2|refseq:XP_011247197.1|entrezgene/locuslink:214384(identity) ensembl:ENSMUSG00000031204(gene)|ensembl:ENSMUST00000033549(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001300672.1|refseq:NP_543134.1|refseq:XP_011245976.1|entrezgene/locuslink:70392(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0drX57b4fxsVTIBKI/U/WwTGFU410090 rogid:mChKqzsKJHIjzxkuW5hR0ISRT1g10090 rigid:lnZPytdg1uLSrkG0OTpk7cGZ8Qk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VIM5 uniprotkb:Q8JZL0 intact:EBI-16354401|ensembl:ENSMUSP00000099695|uniprotkb:Q5SS65|uniprotkb:Q6W8X1|uniprotkb:Q8C3W6|uniprotkb:Q8VIL4 intact:EBI-26673422|ensembl:ENSMUSP00000110207|ensembl:ENSMUSP00000110208|uniprotkb:Q9JJ98 psi-mi:mycd_mouse(display_long)|uniprotkb:Myocd(gene name)|psi-mi:Myocd(display_short)|uniprotkb:Basic SAP coiled-coil transcription activator 2(gene name synonym)|uniprotkb:Bsac2(gene name synonym)|uniprotkb:Mycd(gene name synonym)|uniprotkb:SRF cofactor protein(gene name synonym)|uniprotkb:Srfcp(gene name synonym) psi-mi:zn467_mouse(display_long)|uniprotkb:Endothelial cell-derived zinc finger protein(gene name synonym)|uniprotkb:Znf467(gene name)|psi-mi:Znf467(display_short)|uniprotkb:Ezi(gene name synonym)|uniprotkb:Zfp467(gene name synonym)|uniprotkb:MNCb-3350(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673448|imex:IM-28774-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020542(gene)|ensembl:ENSMUST00000102635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0000785"(chromatin)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043954"(cellular component maintenance)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048565"(digestive tract development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060065"(uterus development)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070514"(SRF-myogenin-E12 complex)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900239"(regulation of phenotypic switching)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000721"(positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|go:"GO:2000724"(positive regulation of cardiac vascular smooth muscle cell differentiation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR028721|interpro:IPR036361|interpro:IPR043451|dip:DIP-29754N|refseq:NP_660118.3|refseq:NP_666498.2|refseq:XP_011247197.1|entrezgene/locuslink:214384(identity) ensembl:ENSMUSG00000068551(gene)|ensembl:ENSMUST00000114560(transcript)|ensembl:ENSMUST00000114561(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001078884.1|refseq:NP_001078885.1|refseq:NP_065614.2|entrezgene/locuslink:68910(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0drX57b4fxsVTIBKI/U/WwTGFU410090 rogid:lWtOaS3lVhOcQcvaIIrCGVRKAJQ10090 rigid:42eZ4akzux5fFT3gM9PGfOyKF70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VIM5 uniprotkb:Q61751 intact:EBI-16354401|ensembl:ENSMUSP00000099695|uniprotkb:Q5SS65|uniprotkb:Q6W8X1|uniprotkb:Q8C3W6|uniprotkb:Q8VIL4 intact:EBI-26673380|ensembl:ENSMUSP00000020628|ensembl:ENSMUSP00000099827|uniprotkb:Q9QXU0 psi-mi:mycd_mouse(display_long)|uniprotkb:Myocd(gene name)|psi-mi:Myocd(display_short)|uniprotkb:Basic SAP coiled-coil transcription activator 2(gene name synonym)|uniprotkb:Bsac2(gene name synonym)|uniprotkb:Mycd(gene name synonym)|uniprotkb:SRF cofactor protein(gene name synonym)|uniprotkb:Srfcp(gene name synonym) psi-mi:z354a_mouse(display_long)|uniprotkb:Kidney, ischemia, and developmentally-regulated protein 1(gene name synonym)|uniprotkb:Renal transcription factor Kid-1(gene name synonym)|uniprotkb:Transcription factor 17(gene name synonym)|uniprotkb:Znf354a(gene name)|psi-mi:Znf354a(display_short)|uniprotkb:Kid1(gene name synonym)|uniprotkb:Tcf17(gene name synonym)|uniprotkb:Zfp354a(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673414|imex:IM-28774-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020542(gene)|ensembl:ENSMUST00000102635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0000785"(chromatin)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043954"(cellular component maintenance)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048565"(digestive tract development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060065"(uterus development)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070514"(SRF-myogenin-E12 complex)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900239"(regulation of phenotypic switching)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000721"(positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|go:"GO:2000724"(positive regulation of cardiac vascular smooth muscle cell differentiation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR028721|interpro:IPR036361|interpro:IPR043451|dip:DIP-29754N|refseq:NP_660118.3|refseq:NP_666498.2|refseq:XP_011247197.1|entrezgene/locuslink:214384(identity) ensembl:ENSMUSG00000020364(gene)|ensembl:ENSMUST00000020628(transcript)|ensembl:ENSMUST00000102766(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007576"(nucleolar fragmentation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR041697|reactome:R-MMU-212436|refseq:NP_001313495.1|refseq:NP_033355.2|refseq:XP_006532853.1|entrezgene/locuslink:21408(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0drX57b4fxsVTIBKI/U/WwTGFU410090 rogid:bDgnQBZ5YOloFmDhpNOZdE25SXQ10090 rigid:xeq7PxyYiOVGKNfikkOoz8LkPlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VIM5 uniprotkb:Q1H9T6 intact:EBI-16354401|ensembl:ENSMUSP00000099695|uniprotkb:Q5SS65|uniprotkb:Q6W8X1|uniprotkb:Q8C3W6|uniprotkb:Q8VIL4 intact:EBI-11104272|uniprotkb:A2A8B1|uniprotkb:Q99K15|ensembl:ENSMUSP00000067521 psi-mi:mycd_mouse(display_long)|uniprotkb:Myocd(gene name)|psi-mi:Myocd(display_short)|uniprotkb:Basic SAP coiled-coil transcription activator 2(gene name synonym)|uniprotkb:Bsac2(gene name synonym)|uniprotkb:Mycd(gene name synonym)|uniprotkb:SRF cofactor protein(gene name synonym)|uniprotkb:Srfcp(gene name synonym) psi-mi:tzap_mouse(display_long)|uniprotkb:Zbtb48(gene name)|psi-mi:Zbtb48(display_short)|uniprotkb:Hkr3(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein 3 homolog(gene name synonym)|uniprotkb:Tzap(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 48(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673372|imex:IM-28774-1103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020542(gene)|ensembl:ENSMUST00000102635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0000785"(chromatin)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043954"(cellular component maintenance)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048565"(digestive tract development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060065"(uterus development)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070514"(SRF-myogenin-E12 complex)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900239"(regulation of phenotypic switching)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000721"(positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|go:"GO:2000724"(positive regulation of cardiac vascular smooth muscle cell differentiation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR028721|interpro:IPR036361|interpro:IPR043451|dip:DIP-29754N|refseq:NP_660118.3|refseq:NP_666498.2|refseq:XP_011247197.1|entrezgene/locuslink:214384(identity) refseq:NP_598640.2|ensembl:ENSMUSG00000028952(gene)|ensembl:ENSMUST00000066715(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2DLQ|rcsb pdb:2YY9|entrezgene/locuslink:100090(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0drX57b4fxsVTIBKI/U/WwTGFU410090 rogid:pdshzPQ1o3vJ3TkzVKPi21ek23A10090 rigid:vyr9GhsIWovVIr325h2wVxUeFUQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97358 uniprotkb:P15806 intact:EBI-8448340|uniprotkb:Q6NSS9|uniprotkb:E9QJY7|intact:MINT-249228|uniprotkb:Q08AT7|uniprotkb:Q3V292|ensembl:ENSMUSP00000075339 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:taf1b_mouse(display_long)|uniprotkb:Taf1b(gene name)|psi-mi:Taf1b(display_short)|uniprotkb:TATA box-binding protein-associated factor 1B(gene name synonym)|uniprotkb:RNA polymerase I-specific TBP-associated factor 68 kDa(gene name synonym)|uniprotkb:Transcription initiation factor SL1/TIF-IB subunit B(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673364|imex:IM-28774-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065639.2|ensembl:ENSMUSG00000059669(gene)|ensembl:ENSMUST00000075954(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005668"(RNA polymerase transcription factor SL1 complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR021752|interpro:IPR033599|mint:P97358|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|entrezgene/locuslink:21340(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - comment:mint|comment:homomint|function:"Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex)" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Omf2Jpu9EuZi+Cyan+0Cj/ztVwQ10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:H4sRVf6ifpoKS2cZ3WN2EUBlWLU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15806 uniprotkb:O35134 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 intact:EBI-26672234|ensembl:ENSMUSP00000060858|uniprotkb:Q7TSA9 psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:rpa1_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:Polr1a(gene name)|psi-mi:Polr1a(display_short)|uniprotkb:Rpa1(gene name synonym)|uniprotkb:Rpo1-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673356|imex:IM-28774-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) ensembl:ENSMUSG00000049553(gene)|ensembl:ENSMUST00000055296(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033114.3|entrezgene/locuslink:20019(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rogid:CsIy49qIGfvmY/epR1XQ+Z54ckE10090 rigid:VX1WmMGIUJR1huuL51AQKyQOqoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTU0 uniprotkb:P15806 intact:EBI-8339791|intact:MINT-4107441|uniprotkb:Q6A023|uniprotkb:Q80WA8|ensembl:ENSMUSP00000047308 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:phf2_mouse(display_long)|uniprotkb:Phf2(gene name)|psi-mi:Phf2(display_short)|uniprotkb:GRC5(gene name synonym)|uniprotkb:Kiaa0662(gene name synonym)|uniprotkb:PHD finger protein 2(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673348|imex:IM-28774-1537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035208.2|ensembl:ENSMUSG00000038025(gene)|ensembl:ENSMUST00000035540(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035574"(histone H4-K20 demethylation)|go:"GO:0035575"(histone H4-methyl-lysine-20 demethylase activity)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|mint:Q9WTU0|reactome:R-MMU-3214842|entrezgene/locuslink:18676(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2RoS6FXstspu+TN1DwCkVySJlUI10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:tZuq8kRSabBsCDd9nt7Ri3L9MA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50220 uniprotkb:P09631 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673846|imex:IM-28774-2849 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:vJz6DIuvvuZbjVVPyv3nxRkPVO0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50220 uniprotkb:Q8K5B8 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673854|imex:IM-28774-3275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:LbLZLJSFOoeXuzYzqG2NSB4PWT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50220 uniprotkb:Q04744 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 intact:EBI-26673795|ensembl:ENSMUSP00000053361|uniprotkb:G3X9A6|uniprotkb:Q80UE7 psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:emx2_mouse(display_long)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym)|uniprotkb:Emx2(gene name)|psi-mi:Emx2(display_short)|uniprotkb:Emx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673830|imex:IM-28774-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) ensembl:ENSMUSG00000043969(gene)|ensembl:ENSMUST00000062216(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034262.2|entrezgene/locuslink:13797(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rogid:K3i+Zeai93MikBwJdzf940evg0I10090 rigid:/GJSx8ppwoNiTew+Hah0jeWyqy4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70318 uniprotkb:Q07279 intact:EBI-299820|ensembl:ENSMUSP00000101833 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:tiar_mouse(display_long)|uniprotkb:Tial1(gene name)|psi-mi:Tial1(display_short)|uniprotkb:TIA-1-related protein(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673787|imex:IM-28774-1111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-6803529|ensembl:ENSMUSG00000030846(gene)|ensembl:ENSMUST00000106226(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0007281"(germ cell development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017145"(stem cell division)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034492|interpro:IPR034494|interpro:IPR034496|interpro:IPR035979|mint:P70318|refseq:NP_033409.1|entrezgene/locuslink:21843(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2AMX8dA/6e4MCBhMBtddiNf4q7I10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:sLt+4axb18p6mIcukKtM6+yMVoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37242 uniprotkb:P28705 intact:EBI-6935043|ensembl:ENSMUSP00000022303|ensembl:ENSMUSP00000089053|uniprotkb:Q3TY80|intact:MINT-3374177|uniprotkb:P37244|uniprotkb:Q0VDR8|intact:MINT-5026988 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 psi-mi:thb_mouse(display_long)|uniprotkb:Thrb(gene name)|psi-mi:Thrb(display_short)|uniprotkb:Nr1a2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group A member 2(gene name synonym)|uniprotkb:Erba2(gene name synonym)|uniprotkb:c-erbA-beta(gene name synonym)|uniprotkb:c-erbA-2(gene name synonym) psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673779|imex:IM-28774-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243039.1|refseq:XP_011243040.1|refseq:XP_011243041.1|refseq:XP_011243042.1|refseq:XP_011243043.1|refseq:XP_011243044.1|refseq:XP_011243045.1|refseq:XP_006518029.1|refseq:XP_006518030.1|refseq:XP_006518031.1|refseq:XP_006518033.1|refseq:XP_006518034.1|refseq:XP_006518035.1|refseq:XP_017171436.1|refseq:XP_017171435.1|ensembl:ENSMUSG00000021779(gene)|ensembl:ENSMUST00000022303(transcript)|ensembl:ENSMUST00000091471(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007621"(negative regulation of female receptivity)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016604"(nuclear body)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097474"(retinal cone cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|mint:P37242|reactome:R-MMU-383280|reactome:R-MMU-4090294|interpro:IPR035500|refseq:NP_001106888.1|refseq:NP_033406.1|dip:DIP-43750N|entrezgene/locuslink:21834(identity) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) - comment:mint|function:High affinity receptor for triiodothyronine - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:e8Wr18Fb02fPIadJyfhqv9l0WZs10090 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rigid:B/w7Ilx54lIYegIXxT2xBV23IiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BJI4 uniprotkb:Q5U4D4 intact:EBI-26673754 intact:EBI-26671846|ensembl:ENSMUSP00000073504 psi-mi:po6f2_mouse(display_long)|uniprotkb:Pou6f2(gene name)|psi-mi:Pou6f2(display_short) psi-mi:q5u4d4_mouse(display_long)|uniprotkb:Pou6f1(gene name)|psi-mi:Pou6f1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673771|imex:IM-28774-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_778171.2|interpro:IPR009057(Homeodomain-like)|interpro:IPR001356(Homeobox)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR033056|interpro:IPR000327(POU-specific)|entrezgene/locuslink:218030(identity) ensembl:ENSMUSG00000009739(gene)|ensembl:ENSMUST00000073837(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|refseq:NP_001291894.1|entrezgene/locuslink:19009(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TGSlIcU/ZrzC6ldcJIxdzj0zuGc10090 rogid:wP6H1mKwYEvA9kQCTw8UnT0Q97410090 rigid:qCns7V6vxnrV7KJpRtrzq79elyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BW74 uniprotkb:P62509 intact:EBI-2291683|uniprotkb:Q6PF83|ensembl:ENSMUSP00000004051 intact:EBI-5274019|uniprotkb:O75454|uniprotkb:O96021|uniprotkb:Q8CHC9|uniprotkb:Q9R1F3|ensembl:ENSMUSP00000027906 psi-mi:hlf_mouse(display_long)|uniprotkb:Hlf(gene name)|psi-mi:Hlf(display_short) psi-mi:err3_mouse(display_long)|uniprotkb:Esrrg(gene name)|psi-mi:Esrrg(display_short)|uniprotkb:Err3(gene name synonym)|uniprotkb:Kiaa0832(gene name synonym)|uniprotkb:Nr3b3(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673746|imex:IM-28774-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766151.1|ensembl:ENSMUSG00000003949(gene)|ensembl:ENSMUST00000004051(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029829|interpro:IPR040223|refseq:XP_006533068.1|refseq:XP_006533069.1|entrezgene/locuslink:217082(identity) refseq:NP_001230721.1|refseq:NP_036065.1|refseq:XP_006497227.1|refseq:XP_006497228.1|refseq:XP_006497230.1|refseq:XP_006497233.1|ensembl:ENSMUSG00000026610(gene)|ensembl:ENSMUST00000027906(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1S9P|rcsb pdb:1S9Q|reactome:R-MMU-383280|entrezgene/locuslink:26381(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:y5F0fojcgowlcfCDibYYhBIj8lw10090 rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk10090 rigid:J5pHAsV/XZO0xW/uWuauHg5iDX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BW74 uniprotkb:Q60925 intact:EBI-2291683|uniprotkb:Q6PF83|ensembl:ENSMUSP00000004051 intact:EBI-26673677|ensembl:ENSMUSP00000079693|uniprotkb:Q8VCX3 psi-mi:hlf_mouse(display_long)|uniprotkb:Hlf(gene name)|psi-mi:Hlf(display_short) psi-mi:dbp_mouse(display_long)|uniprotkb:Albumin D box-binding protein(gene name synonym)|uniprotkb:Albumin D-element-binding protein(gene name synonym)|uniprotkb:Dbp(gene name)|psi-mi:Dbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673738|imex:IM-28774-2015 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766151.1|ensembl:ENSMUSG00000003949(gene)|ensembl:ENSMUST00000004051(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029829|interpro:IPR040223|refseq:XP_006533068.1|refseq:XP_006533069.1|entrezgene/locuslink:217082(identity) ensembl:ENSMUSG00000059824(gene)|ensembl:ENSMUST00000080885(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029830|interpro:IPR040223|refseq:NP_058670.2|entrezgene/locuslink:13170(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:y5F0fojcgowlcfCDibYYhBIj8lw10090 rogid:lcwsGCIxlexVpSuZTjEuZDgymlA10090 rigid:yciCNFE+S6AJhgRf1IxAKJvCUMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JLC6 uniprotkb:Q60925 intact:EBI-26673698|ensembl:ENSMUSP00000023024|uniprotkb:Q3U426|uniprotkb:Q3UGF4|uniprotkb:Q3UM49|uniprotkb:Q3URC8|uniprotkb:Q6QHT6|uniprotkb:Q8C6I0|uniprotkb:Q8VD02 intact:EBI-26673677|ensembl:ENSMUSP00000079693|uniprotkb:Q8VCX3 psi-mi:tef_mouse(display_long)|uniprotkb:Tef(gene name)|psi-mi:Tef(display_short) psi-mi:dbp_mouse(display_long)|uniprotkb:Albumin D box-binding protein(gene name synonym)|uniprotkb:Albumin D-element-binding protein(gene name synonym)|uniprotkb:Dbp(gene name)|psi-mi:Dbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673730|imex:IM-28774-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022389(gene)|ensembl:ENSMUST00000023024(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029832|interpro:IPR040223|refseq:NP_059072.1|refseq:NP_705617.2|entrezgene/locuslink:21685(identity) ensembl:ENSMUSG00000059824(gene)|ensembl:ENSMUST00000080885(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029830|interpro:IPR040223|refseq:NP_058670.2|entrezgene/locuslink:13170(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jwxlAGyo8n8VADk3MLvjSIP19lE10090 rogid:lcwsGCIxlexVpSuZTjEuZDgymlA10090 rigid:l4DVNb/SOV0RQCJz+udDdA2s8zg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z1B8 uniprotkb:Q61545 intact:EBI-8372983|uniprotkb:O54808|intact:MINT-4107427|ensembl:ENSMUSP00000073402 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:phf1_mouse(display_long)|uniprotkb:Phf1(gene name)|psi-mi:Phf1(display_short)|uniprotkb:Tctex3(gene name synonym)|uniprotkb:Tctex-3(gene name synonym)|uniprotkb:Plc1(gene name synonym)|uniprotkb:T-complex testis-expressed 3(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673669|imex:IM-28774-2847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033369.2|ensembl:ENSMUSG00000024193(gene)|ensembl:ENSMUST00000073724(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|mint:Q9Z1B8|rcsb pdb:5XFQ|reactome:R-MMU-212300|interpro:IPR031202|entrezgene/locuslink:21652(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2sifYf2VBVW+iFcRCG1PbQUcisI10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:DvqE+yzd7qIJ1+nZyaf7lntlgRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q8BP71 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-8821142|ensembl:ENSMUSP00000130739|uniprotkb:Q0R5Z7|uniprotkb:Q0R5Z8|uniprotkb:Q0VH84|uniprotkb:Q537D4|uniprotkb:Q537D5|uniprotkb:Q8BRG0|uniprotkb:Q8R2T5|uniprotkb:Q8VI62|uniprotkb:Q923W8 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:rfox2_mouse(display_long)|uniprotkb:Rbfox2(gene name)|psi-mi:Rbfox2(display_short)|uniprotkb:Fox2(gene name synonym)|uniprotkb:Fxh(gene name synonym)|uniprotkb:Hrnbp2(gene name synonym)|uniprotkb:Rbm9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Fox-1 homolog Fxh(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673661|imex:IM-28774-1109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) refseq:NP_001273346.1|refseq:NP_001273347.1|refseq:NP_001273348.1|ensembl:ENSMUSG00000033565(gene)|ensembl:ENSMUST00000171751(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR025670|interpro:IPR034237|interpro:IPR035979|mint:Q8BP71|reactome:R-MMU-6803529|refseq:NP_001104297.1|refseq:NP_001104298.1|refseq:NP_001104299.1|refseq:NP_001104300.1|refseq:NP_444334.3|refseq:NP_780596.1|entrezgene/locuslink:93686(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:HRi3RnK49EYIZ7cCYmfqcmsudow10090 rigid:5FcIrvaTT0vvA+VPZ9mZiPPxZZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3UW74 uniprotkb:Q9Z0G7 intact:EBI-5745202|ensembl:ENSMUSP00000129375 intact:EBI-16732462|ensembl:ENSMUSP00000057466 psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:zbt22_mouse(display_long)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Zbtb22(gene name)|psi-mi:Zbtb22(display_short)|uniprotkb:Bing1(gene name synonym)|uniprotkb:Zfp297(gene name synonym)|uniprotkb:Znf297(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673653|imex:IM-28774-1545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) ensembl:ENSMUSG00000051390(gene)|ensembl:ENSMUST00000053429(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|refseq:NP_065650.1|entrezgene/locuslink:81630(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rogid:ZUg4jLqKYHyBigBV0SXAd5XM6YY10090 rigid:4qiSvpD88tqzIkJTkPISoom56D4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JJP2 uniprotkb:Q9JJP2 intact:EBI-1770138|intact:EBI-1770168|uniprotkb:B1AX89|uniprotkb:B1AX90|uniprotkb:Q3UT91|uniprotkb:Q9CU77|uniprotkb:Q9JJP1|uniprotkb:Q9WUJ0|ensembl:ENSMUSP00000101269 intact:EBI-1770138|intact:EBI-1770168|uniprotkb:B1AX89|uniprotkb:B1AX90|uniprotkb:Q3UT91|uniprotkb:Q9CU77|uniprotkb:Q9JJP1|uniprotkb:Q9WUJ0|ensembl:ENSMUSP00000101269 psi-mi:p73_mouse(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:p73_mouse(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674018|imex:IM-28774-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001119802.1|refseq:NP_001119803.1|refseq:NP_035772.2|dip:DIP-41942N|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030054"(cell junction)|go:"GO:0030900"(forebrain development)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:Q9JJP2|reactome:R-MMU-6804759|reactome:R-MMU-8939236|entrezgene/locuslink:22062(identity) refseq:NP_001119802.1|refseq:NP_001119803.1|refseq:NP_035772.2|dip:DIP-41942N|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030054"(cell junction)|go:"GO:0030900"(forebrain development)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:Q9JJP2|reactome:R-MMU-6804759|reactome:R-MMU-8939236|entrezgene/locuslink:22062(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090 rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090 rigid:fFW+XgjWdAdEIggIprstxdpDNFo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JJP2 uniprotkb:O88898 intact:EBI-1770138|intact:EBI-1770168|uniprotkb:B1AX89|uniprotkb:B1AX90|uniprotkb:Q3UT91|uniprotkb:Q9CU77|uniprotkb:Q9JJP1|uniprotkb:Q9WUJ0|ensembl:ENSMUSP00000101269 intact:EBI-2338025|uniprotkb:O88897|uniprotkb:O88899|uniprotkb:O89097|uniprotkb:Q8C826|uniprotkb:Q9QWY9|uniprotkb:Q9QWZ0|ensembl:ENSMUSP00000110965 psi-mi:p73_mouse(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:p63_mouse(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674010|imex:IM-28774-2447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001119802.1|refseq:NP_001119803.1|refseq:NP_035772.2|dip:DIP-41942N|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030054"(cell junction)|go:"GO:0030900"(forebrain development)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:Q9JJP2|reactome:R-MMU-6804759|reactome:R-MMU-8939236|entrezgene/locuslink:22062(identity) refseq:NP_001120731.1|refseq:NP_001120732.1|refseq:NP_001120733.1|refseq:NP_001120734.1|refseq:NP_001120736.1|refseq:NP_001120737.1|refseq:NP_035771.1|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0010481"(epidermal cell division)|go:"GO:0001501"(skeletal system development)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001942"(hair follicle development)|go:"GO:0002039"(p53 binding)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007389"(pattern specification process)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0098773"(skin epidermis development)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:O88898|rcsb pdb:5N2O|reactome:R-MMU-6804759|entrezgene/locuslink:22061(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rigid:aE42eBFD56w1cyqLMu+ZnCHdt2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JJP2 uniprotkb:O88898 intact:EBI-1770138|intact:EBI-1770168|uniprotkb:B1AX89|uniprotkb:B1AX90|uniprotkb:Q3UT91|uniprotkb:Q9CU77|uniprotkb:Q9JJP1|uniprotkb:Q9WUJ0|ensembl:ENSMUSP00000101269 intact:EBI-2338025|uniprotkb:O88897|uniprotkb:O88899|uniprotkb:O89097|uniprotkb:Q8C826|uniprotkb:Q9QWY9|uniprotkb:Q9QWZ0|ensembl:ENSMUSP00000110965 psi-mi:p73_mouse(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:p63_mouse(display_long)|uniprotkb:Tp63(gene name)|psi-mi:Tp63(display_short)|uniprotkb:P63(gene name synonym)|uniprotkb:P73l(gene name synonym)|uniprotkb:Tp73l(gene name synonym)|uniprotkb:Trp63(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674002|imex:IM-28774-3277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001119802.1|refseq:NP_001119803.1|refseq:NP_035772.2|dip:DIP-41942N|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030054"(cell junction)|go:"GO:0030900"(forebrain development)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:Q9JJP2|reactome:R-MMU-6804759|reactome:R-MMU-8939236|entrezgene/locuslink:22062(identity) refseq:NP_001120731.1|refseq:NP_001120732.1|refseq:NP_001120733.1|refseq:NP_001120734.1|refseq:NP_001120736.1|refseq:NP_001120737.1|refseq:NP_035771.1|ensembl:ENSMUSG00000022510(gene)|ensembl:ENSMUST00000115310(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0010481"(epidermal cell division)|go:"GO:0001501"(skeletal system development)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001942"(hair follicle development)|go:"GO:0002039"(p53 binding)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007389"(pattern specification process)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0098773"(skin epidermis development)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:O88898|rcsb pdb:5N2O|reactome:R-MMU-6804759|entrezgene/locuslink:22061(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090 rogid:QBGrAxpFl3xzWeZFCSy0nxhzmiY10090 rigid:aE42eBFD56w1cyqLMu+ZnCHdt2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z1L3 uniprotkb:Q61545 intact:EBI-26673960|ensembl:ENSMUSP00000068419|ensembl:ENSMUSP00000095075|ensembl:ENSMUSP00000106930|ensembl:ENSMUSP00000106931|uniprotkb:Q7TQH8|uniprotkb:Q9R227 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:dedd_mouse(display_long)|uniprotkb:DEDPro1(gene name synonym)|uniprotkb:Dedd(gene name)|psi-mi:Dedd(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673994|imex:IM-28774-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000013973(gene)|ensembl:ENSMUST00000064950(transcript)|ensembl:ENSMUST00000097467(transcript)|ensembl:ENSMUST00000111299(transcript)|ensembl:ENSMUST00000111300(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046697"(decidualization)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR038856|refseq:NP_001122081.1|refseq:NP_035745.3|refseq:XP_006496801.1|refseq:XP_006496802.1|refseq:XP_006496803.1|refseq:XP_006496804.1|refseq:XP_011237084.1|entrezgene/locuslink:21945(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JLB4zpuTZG/BfJCBj73PPBiTzEs10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:rre6xLNoZS+VCaMo4MqcAy9NG1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60769 uniprotkb:O88522 intact:EBI-646595|uniprotkb:Q3U968|ensembl:ENSMUSP00000019997|ensembl:ENSMUSP00000101167 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:tnap3_mouse(display_long)|uniprotkb:Putative DNA-binding protein A20(gene name synonym)|uniprotkb:Zinc finger protein A20(gene name synonym)|uniprotkb:Tnfaip3(gene name)|psi-mi:Tnfaip3(display_short)|uniprotkb:Tnfip3(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673943|imex:IM-28774-1547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033423.3|dip:DIP-41120N|refseq:XP_006512765.1|ensembl:ENSMUSG00000019850(gene)|ensembl:ENSMUST00000019997(transcript)|ensembl:ENSMUST00000105527(transcript)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002632"(negative regulation of granuloma formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019900"(kinase binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034148"(negative regulation of toll-like receptor 5 signaling pathway)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070429"(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0072573"(tolerance induction to lipopolysaccharide)|go:"GO:0072666"(establishment of protein localization to vacuole)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1990168"(protein K33-linked deubiquitination)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR033478|mint:Q60769|rcsb pdb:5DQ6|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689896|reactome:R-MMU-936440|entrezgene/locuslink:21929(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hFNjd3fxx9grjtEq3kAdU0fiFh010090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:Q37nujmEk2jkZEPc7lMqXfB7qik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q9QX99 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26673886|ensembl:ENSMUSP00000026236 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:q9qx99_mouse(display_long)|uniprotkb:Tlx1(gene name)|psi-mi:Tlx1(display_short)|uniprotkb:Hox11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673935|imex:IM-28774-2021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000025215(gene)|ensembl:ENSMUST00000026236(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_068701.1|entrezgene/locuslink:21908(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:hPhtzEYq+1ZgGG0WxBwFzTd7bO410090 rigid:DhQaRRbvB0rfIEVodZZhseNDNBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q9QX99 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26673886|ensembl:ENSMUSP00000026236 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:q9qx99_mouse(display_long)|uniprotkb:Tlx1(gene name)|psi-mi:Tlx1(display_short)|uniprotkb:Hox11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673927|imex:IM-28774-2019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000025215(gene)|ensembl:ENSMUST00000026236(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_068701.1|entrezgene/locuslink:21908(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:hPhtzEYq+1ZgGG0WxBwFzTd7bO410090 rigid:DhQaRRbvB0rfIEVodZZhseNDNBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QX99 uniprotkb:Q60954 intact:EBI-26673886|ensembl:ENSMUSP00000026236 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:q9qx99_mouse(display_long)|uniprotkb:Tlx1(gene name)|psi-mi:Tlx1(display_short)|uniprotkb:Hox11(gene name synonym) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673919|imex:IM-28774-2855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025215(gene)|ensembl:ENSMUST00000026236(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_068701.1|entrezgene/locuslink:21908(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hPhtzEYq+1ZgGG0WxBwFzTd7bO410090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:/KpRVyzxj4PK12HicpaJ7KpX1DA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QX99 uniprotkb:Q04744 intact:EBI-26673886|ensembl:ENSMUSP00000026236 intact:EBI-26673795|ensembl:ENSMUSP00000053361|uniprotkb:G3X9A6|uniprotkb:Q80UE7 psi-mi:q9qx99_mouse(display_long)|uniprotkb:Tlx1(gene name)|psi-mi:Tlx1(display_short)|uniprotkb:Hox11(gene name synonym) psi-mi:emx2_mouse(display_long)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym)|uniprotkb:Emx2(gene name)|psi-mi:Emx2(display_short)|uniprotkb:Emx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673911|imex:IM-28774-2017 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025215(gene)|ensembl:ENSMUST00000026236(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_068701.1|entrezgene/locuslink:21908(identity) ensembl:ENSMUSG00000043969(gene)|ensembl:ENSMUST00000062216(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034262.2|entrezgene/locuslink:13797(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hPhtzEYq+1ZgGG0WxBwFzTd7bO410090 rogid:K3i+Zeai93MikBwJdzf940evg0I10090 rigid:v3oJKhDikJdJsAUkUkGUxOHk7s8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QX99 uniprotkb:Q04742 intact:EBI-26673886|ensembl:ENSMUSP00000026236 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:q9qx99_mouse(display_long)|uniprotkb:Tlx1(gene name)|psi-mi:Tlx1(display_short)|uniprotkb:Hox11(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673903|imex:IM-28774-1115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025215(gene)|ensembl:ENSMUST00000026236(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_068701.1|entrezgene/locuslink:21908(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hPhtzEYq+1ZgGG0WxBwFzTd7bO410090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:nFyqGSBSpPd99FIK6EfTAsMq01c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22605 uniprotkb:Q8C0D7 intact:EBI-2903247|uniprotkb:P11417|uniprotkb:P22604 intact:EBI-645598|uniprotkb:Q8C1S7|uniprotkb:Q8K3Q5|uniprotkb:Q8K3Q6|uniprotkb:Q8K3Q7|uniprotkb:Q9D7F9|ensembl:ENSMUSP00000121519 psi-mi:rarb_mouse(display_long)|uniprotkb:Rarb(gene name)|psi-mi:Rarb(display_short)|uniprotkb:Nr1b2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym) psi-mi:ing4_mouse(display_long)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:Ing4(gene name)|psi-mi:Ing4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673878|imex:IM-28774-2853 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060348"(bone development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1XDK|reactome:R-MMU-383280|reactome:R-MMU-5362517|go:"GO:0043068"(positive regulation of programmed cell death)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|refseq:NP_001276689.1|refseq:NP_001276690.1|refseq:NP_001276691.1|refseq:NP_035373.1|interpro:IPR035500|mint:P22605|entrezgene/locuslink:218772(identity) refseq:NP_579923.1|ensembl:ENSMUSG00000030330(gene)|ensembl:ENSMUST00000140131(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8C0D7|rcsb pdb:1WEN|rcsb pdb:1WEU|reactome:R-MMU-3214847|entrezgene/locuslink:28019(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jsfH728g22P17Xkv1lfsyBLPwgE10090 rogid:i6BnXl7FG4akcSbiC3prvkZud6k10090 rigid:FppJ06/n+jD7v07zJJp7rwReW9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06537 uniprotkb:P22605 intact:EBI-492753|uniprotkb:Q61628|uniprotkb:Q61629|ensembl:ENSMUSP00000025300|ensembl:ENSMUSP00000095199|ensembl:ENSMUSP00000111229|ensembl:ENSMUSP00000111233|intact:EBI-26668912|uniprotkb:E9PUR6|uniprotkb:E0ZPU5|uniprotkb:Q06VW2|uniprotkb:Q3U126|uniprotkb:Q3U2M7|uniprotkb:E9PYV1 intact:EBI-2903247|uniprotkb:P11417|uniprotkb:P22604 psi-mi:gcr_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym)|uniprotkb:Grl1(gene name synonym) psi-mi:rarb_mouse(display_long)|uniprotkb:Rarb(gene name)|psi-mi:Rarb(display_short)|uniprotkb:Nr1b2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673870|imex:IM-28774-1113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024431(gene)|ensembl:ENSMUST00000025300(transcript)|ensembl:ENSMUST00000097592(transcript)|ensembl:ENSMUST00000115567(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|ensembl:ENSMUST00000115571(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|reactome:R-MMU-3371497|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048096"|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P06537|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|refseq:NP_032199.3|refseq:XP_006525721.1|refseq:XP_006525722.1|refseq:XP_006525723.1|refseq:XP_006525724.1|refseq:XP_006525725.1|refseq:XP_006525726.1|refseq:XP_006525727.1|refseq:XP_006525728.1|refseq:XP_006525729.1|refseq:XP_017173324.1|refseq:XP_017173325.1|refseq:XP_017173326.1|refseq:XP_017173327.1|dip:DIP-11N|entrezgene/locuslink:14815(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060348"(bone development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1XDK|reactome:R-MMU-383280|reactome:R-MMU-5362517|go:"GO:0043068"(positive regulation of programmed cell death)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|refseq:NP_001276689.1|refseq:NP_001276690.1|refseq:NP_001276691.1|refseq:NP_035373.1|interpro:IPR035500|mint:P22605|entrezgene/locuslink:218772(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/11/30 rogid:BGeJbz2zNEPZBn4cdswdbgRBif410090 rogid:jsfH728g22P17Xkv1lfsyBLPwgE10090 rigid:LYz9ZZJ90gKXyPBFkcMHrkRF9kQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00288 uniprotkb:P50220 intact:EBI-1395397|uniprotkb:Q6GU20|uniprotkb:P97342|ensembl:ENSMUSP00000028355 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 psi-mi:pax8_mouse(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673862|imex:IM-28774-2851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035170.1|ensembl:ENSMUSG00000026976(gene)|ensembl:ENSMUST00000028355(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|entrezgene/locuslink:18510(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:41aRv6r+djf0uC8katu9eOUnmJs10090 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rigid:x2lAsv0+fTlBORWTz0gxjCpcNeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50220 uniprotkb:P43136 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673838|imex:IM-28774-3273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:13864(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rigid:A/opWS1OCv1nNQnzi5Uolb+o0OE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A2AQR4 uniprotkb:A2AQR4 intact:EBI-26673603|ensembl:ENSMUSP00000085285 intact:EBI-26673603|ensembl:ENSMUSP00000085285 psi-mi:a2aqr4_mouse(display_long)|uniprotkb:Zfp64(gene name)|psi-mi:Zfp64(display_short) psi-mi:a2aqr4_mouse(display_long)|uniprotkb:Zfp64(gene name)|psi-mi:Zfp64(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674590|imex:IM-28774-2461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027551(gene)|ensembl:ENSMUST00000087971(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_033590.2|entrezgene/locuslink:22722(identity) ensembl:ENSMUSG00000027551(gene)|ensembl:ENSMUST00000087971(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_033590.2|entrezgene/locuslink:22722(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:zzFaR9hgXdPiH+QNw8QFmUi0A9s10090 rogid:zzFaR9hgXdPiH+QNw8QFmUi0A9s10090 rigid:MrFnrsuoDDj7UMkEJhxqnAWZvfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61187 uniprotkb:O88522 intact:EBI-1202711|ensembl:ENSMUSP00000014546 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:ts101_mouse(display_long)|uniprotkb:Tsg101(gene name)|psi-mi:Tsg101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674035|imex:IM-28774-2023 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068684.1|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|reactome:R-MMU-917729|ensembl:ENSMUSG00000014402(gene)|ensembl:ENSMUST00000014546(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:22088(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xaaLuoyhyn1UgchT9KTyD5FCTHg10090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:jcuT488kCcsNj5Fr28E8CZBZQa0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22227 uniprotkb:Q61545 intact:EBI-2313372|uniprotkb:Q4KMN3|uniprotkb:Q7TPU3 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zfp42_mouse(display_long)|uniprotkb:Zfp42(gene name)|psi-mi:Zfp42(display_short)|uniprotkb:Rex-1(gene name synonym)|uniprotkb:Rex1(gene name synonym)|uniprotkb:Reduced expression protein 1(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674544|imex:IM-28774-3285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033582.2|mint:P22227|dip:DIP-54911N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22702(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:REI3nJ1n09QYCKp2R/9lgwV54EA10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:StdpLiSoUZiDKUz3ZSTTs6ADhXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07231 uniprotkb:Q60953 intact:EBI-26674494|ensembl:ENSMUSP00000053430|ensembl:ENSMUSP00000079557|ensembl:ENSMUSP00000106584|ensembl:ENSMUSP00000106585|ensembl:ENSMUSP00000106586|uniprotkb:Q921V2 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:zsc21_mouse(display_long)|uniprotkb:CtFIN51(gene name synonym)|uniprotkb:Transcription factor RU49(gene name synonym)|uniprotkb:Zinc finger protein 38(gene name synonym)|uniprotkb:Zscan21(gene name)|psi-mi:Zscan21(display_short)|uniprotkb:Zfp-38(gene name synonym)|uniprotkb:Zfp38(gene name synonym)|uniprotkb:Zipro1(gene name synonym)|uniprotkb:Znf38(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674536|imex:IM-28774-2459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000037017(gene)|ensembl:ENSMUST00000062350(transcript)|ensembl:ENSMUST00000080732(transcript)|ensembl:ENSMUST00000110959(transcript)|ensembl:ENSMUST00000110960(transcript)|ensembl:ENSMUST00000110961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:NP_001038168.1|refseq:NP_001038169.1|refseq:NP_001038170.1|refseq:NP_035887.2|refseq:XP_011239244.1|entrezgene/locuslink:22697(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tBj0f3NQ9v5VMhDEh84ZhSGs1P810090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:ywb6JgWbuRCA0OyZZWCifRZ/KHw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60585 uniprotkb:P09632 intact:EBI-26674470|uniprotkb:Q9CRV9 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:zfp30_mouse(display_long)|uniprotkb:Zfp30(gene name)|psi-mi:Zfp30(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674486|imex:IM-28774-2863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|refseq:NP_038733.1|reactome:R-MMU-212436|interpro:IPR001909(Krueppel-associated box)|interpro:IPR036051|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:22693(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IqIzz0n3i+DrWbXpE9CU+p2Tq5c10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:aRl6QcTsiNx2Ql7NOAvbTxVQ3R4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07230 uniprotkb:Q07279 intact:EBI-26665895|ensembl:ENSMUSP00000042321 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:zsca2_mouse(display_long)|uniprotkb:Zinc finger protein 29(gene name synonym)|uniprotkb:Zscan2(gene name)|psi-mi:Zscan2(display_short)|uniprotkb:Zfp-29(gene name synonym)|uniprotkb:Zfp29(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674462|imex:IM-28774-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|rcsb pdb:2I13|ensembl:ENSMUSG00000038797(gene)|ensembl:ENSMUST00000044115(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|refseq:NP_033579.1|refseq:XP_006540868.1|refseq:XP_006540869.1|refseq:XP_006540870.1|refseq:XP_006540871.1|refseq:XP_006540872.1|refseq:XP_006540873.1|refseq:XP_006540874.1|refseq:XP_006540875.1|entrezgene/locuslink:22691(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TKkA1qeOjBvBBvqNNMoIA8zG87w10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:h6XtJf/BKgmkRgDTfNOULR8e46M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70255 uniprotkb:P10078 intact:EBI-8357800|uniprotkb:Q9R1G3|uniprotkb:Q99MA4|uniprotkb:O09072|uniprotkb:P70256|uniprotkb:Q99MA3|uniprotkb:Q99MA7|intact:MINT-4103664|uniprotkb:Q99MA8|uniprotkb:Q99MA5|uniprotkb:Q3U2I9|uniprotkb:Q99MA6|ensembl:ENSMUSP00000020461 intact:EBI-26674431|ensembl:ENSMUSP00000079812|uniprotkb:Q61776|uniprotkb:Q8BT11|uniprotkb:Q8C836 psi-mi:nfic_mouse(display_long)|uniprotkb:Nfic(gene name)|psi-mi:Nfic(display_short)|uniprotkb:Nuclear factor I/C(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:zfp28_mouse(display_long)|uniprotkb:Protein mKR5(gene name synonym)|uniprotkb:Zfp28(gene name)|psi-mi:Zfp28(display_short)|uniprotkb:Mkr5(gene name synonym)|uniprotkb:Zfp-28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674454|imex:IM-28774-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032714.1|refseq:XP_006513398.1|ensembl:ENSMUSG00000055053(gene)|ensembl:ENSMUST00000020461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|mint:P70255|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:18029(identity) ensembl:ENSMUSG00000062861(gene)|ensembl:ENSMUST00000081022(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_780456.2|entrezgene/locuslink:22690(identity) - comment:mint|function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xlCYnyhtNzNZPyZ7keQGNLhXeao10090 rogid:ZXOGRDcmfDQJGFgRavctVeWHZj010090 rigid:K9Hmc0uHpHeAcLyRamZz436A93E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C092 uniprotkb:P54841 intact:EBI-12667248|uniprotkb:Q8BTR2 intact:EBI-16093217|ensembl:ENSMUSP00000096728|uniprotkb:Q3U3C8|uniprotkb:Q3UPT9 psi-mi:taf5_mouse(display_long)|uniprotkb:Taf5(gene name)|psi-mi:Taf5(display_short)|uniprotkb:Transcription initiation factor TFIID 100 kDa subunit(gene name synonym) psi-mi:mafb_mouse(display_long)|uniprotkb:Mafb(gene name)|psi-mi:Mafb(display_short)|uniprotkb:Krml(gene name synonym)|uniprotkb:Maf1(gene name synonym)|uniprotkb:Kreisler(gene name synonym)|uniprotkb:Segmentation protein Kr(gene name synonym)|uniprotkb:Transcription factor Maf-1(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674423|imex:IM-28774-2037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796316.2|interpro:IPR020472|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1990841"(promoter-specific chromatin binding)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|interpro:IPR037783|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037264|entrezgene/locuslink:226182(identity) ensembl:ENSMUSG00000074622(gene)|ensembl:ENSMUST00000099126(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048538"(thymus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|rcsb pdb:2WT7|rcsb pdb:2WTY|rcsb pdb:4AUW|refseq:NP_034788.1|dip:DIP-60663N|entrezgene/locuslink:16658(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iDpKf85r1pKLAdwDOwZtaDaePHs10090 rogid:1DQ2XUBtEbI4yQGBXhWL4xh3hCE10090 rigid:SJFqTb9PWEyV3lBNtEzFynwsdh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R1B8 uniprotkb:Q8BW74 intact:EBI-26674334|ensembl:ENSMUSP00000047597|uniprotkb:Q0PQZ2|uniprotkb:Q0PQZ3|uniprotkb:Q1MVR9 intact:EBI-2291683|uniprotkb:Q6PF83|ensembl:ENSMUSP00000004051 psi-mi:rorb_mouse(display_long)|uniprotkb:Nuclear receptor RZR-beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 2(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-beta(gene name synonym)|uniprotkb:Rorb(gene name)|psi-mi:Rorb(display_short)|uniprotkb:Nr1f2(gene name synonym) psi-mi:hlf_mouse(display_long)|uniprotkb:Hlf(gene name)|psi-mi:Hlf(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674415|imex:IM-28774-2457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036192(gene)|ensembl:ENSMUST00000040153(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|reactome:R-MMU-383280|refseq:NP_001036819.1|refseq:NP_001276850.1|refseq:NP_666207.3|entrezgene/locuslink:225998(identity) refseq:NP_766151.1|ensembl:ENSMUSG00000003949(gene)|ensembl:ENSMUST00000004051(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029829|interpro:IPR040223|refseq:XP_006533068.1|refseq:XP_006533069.1|entrezgene/locuslink:217082(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJ0jdVKsXz4G43m0qLJdRTGfyAE10090 rogid:y5F0fojcgowlcfCDibYYhBIj8lw10090 rigid:cAhiZWcqmBumXFKB2IJL7X2TfnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R1B8 uniprotkb:Q9QZB6 intact:EBI-26674334|ensembl:ENSMUSP00000047597|uniprotkb:Q0PQZ2|uniprotkb:Q0PQZ3|uniprotkb:Q1MVR9 intact:EBI-26670677|ensembl:ENSMUSP00000030025|uniprotkb:Q9QZB5 psi-mi:rorb_mouse(display_long)|uniprotkb:Nuclear receptor RZR-beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 2(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-beta(gene name synonym)|uniprotkb:Rorb(gene name)|psi-mi:Rorb(display_short)|uniprotkb:Nr1f2(gene name synonym) psi-mi:nr4a3_mouse(display_long)|uniprotkb:Orphan nuclear receptor TEC(gene name synonym)|uniprotkb:Translocated in extraskeletal chondrosarcoma(gene name synonym)|uniprotkb:Nr4a3(gene name)|psi-mi:Nr4a3(display_short)|uniprotkb:Tec(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674407|imex:IM-28774-1563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036192(gene)|ensembl:ENSMUST00000040153(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|reactome:R-MMU-383280|refseq:NP_001036819.1|refseq:NP_001276850.1|refseq:NP_666207.3|entrezgene/locuslink:225998(identity) ensembl:ENSMUSG00000028341(gene)|ensembl:ENSMUST00000030025(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007411"(axon guidance)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009444"(pyruvate oxidation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030534"(adult behavior)|go:"GO:0032765"(positive regulation of mast cell cytokine production)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0038097"(positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045333"(cellular respiration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060005"(vestibular reflex)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900625"(positive regulation of monocyte aggregation)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000108"(positive regulation of leukocyte apoptotic process)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003072(Orphan nuclear receptor, NOR1 type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001294918.1|refseq:NP_056558.1|refseq:XP_006537719.1|refseq:XP_006537720.1|refseq:XP_006537721.1|entrezgene/locuslink:18124(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJ0jdVKsXz4G43m0qLJdRTGfyAE10090 rogid:hvk9nzkP+G3jLluo4cGSjr+j5Cs10090 rigid:17jjSuA01eJk/7txL6DFyz2hr38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R1B8 uniprotkb:Q05BA5 intact:EBI-26674334|ensembl:ENSMUSP00000047597|uniprotkb:Q0PQZ2|uniprotkb:Q0PQZ3|uniprotkb:Q1MVR9 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:rorb_mouse(display_long)|uniprotkb:Nuclear receptor RZR-beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 2(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-beta(gene name synonym)|uniprotkb:Rorb(gene name)|psi-mi:Rorb(display_short)|uniprotkb:Nr1f2(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674399|imex:IM-28774-2455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036192(gene)|ensembl:ENSMUST00000040153(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|reactome:R-MMU-383280|refseq:NP_001036819.1|refseq:NP_001276850.1|refseq:NP_666207.3|entrezgene/locuslink:225998(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJ0jdVKsXz4G43m0qLJdRTGfyAE10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:Zh5It85xT+UYFq/gvSL134MZKog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R1B8 uniprotkb:Q61645 intact:EBI-26674334|ensembl:ENSMUSP00000047597|uniprotkb:Q0PQZ2|uniprotkb:Q0PQZ3|uniprotkb:Q1MVR9 intact:EBI-21991144|uniprotkb:Q80Y47|ensembl:ENSMUSP00000022691|ensembl:ENSMUSP00000124816 psi-mi:rorb_mouse(display_long)|uniprotkb:Nuclear receptor RZR-beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 2(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-beta(gene name synonym)|uniprotkb:Rorb(gene name)|psi-mi:Rorb(display_short)|uniprotkb:Nr1f2(gene name synonym) psi-mi:hair_mouse(display_long)|uniprotkb:Hr(gene name)|psi-mi:Hr(display_short)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674391|imex:IM-28774-2861 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036192(gene)|ensembl:ENSMUST00000040153(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|reactome:R-MMU-383280|refseq:NP_001036819.1|refseq:NP_001276850.1|refseq:NP_666207.3|entrezgene/locuslink:225998(identity) refseq:NP_068677.2|refseq:XP_011243268.1|ensembl:ENSMUSG00000022096(gene)|ensembl:ENSMUST00000022691(transcript)|ensembl:ENSMUST00000161069(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|entrezgene/locuslink:15460(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJ0jdVKsXz4G43m0qLJdRTGfyAE10090 rogid:9/Ts7qpEFX5F+Sb7TT+I9aFeaPs10090 rigid:H3ZiTfq+yB4eOPLkpZsWLUJBJyk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R1B8 uniprotkb:P97489 intact:EBI-26674334|ensembl:ENSMUSP00000047597|uniprotkb:Q0PQZ2|uniprotkb:Q0PQZ3|uniprotkb:Q1MVR9 intact:EBI-26673507|ensembl:ENSMUSP00000015771|uniprotkb:Q3UQR0 psi-mi:rorb_mouse(display_long)|uniprotkb:Nuclear receptor RZR-beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 2(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-beta(gene name synonym)|uniprotkb:Rorb(gene name)|psi-mi:Rorb(display_short)|uniprotkb:Nr1f2(gene name synonym) psi-mi:gata5_mouse(display_long)|uniprotkb:GATA-binding factor 5(gene name synonym)|uniprotkb:Gata5(gene name)|psi-mi:Gata5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674383|imex:IM-28774-2859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036192(gene)|ensembl:ENSMUST00000040153(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|reactome:R-MMU-383280|refseq:NP_001036819.1|refseq:NP_001276850.1|refseq:NP_666207.3|entrezgene/locuslink:225998(identity) ensembl:ENSMUSG00000015627(gene)|ensembl:ENSMUST00000015771(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003274"(endocardial cushion fusion)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0062000"(positive regulation of cardiac endothelial to mesenchymal transition)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|reactome:R-MMU-983231|refseq:NP_032119.2|refseq:XP_006500617.1|entrezgene/locuslink:14464(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJ0jdVKsXz4G43m0qLJdRTGfyAE10090 rogid:7Q0sDjuro6dsfi8e2XYl3jVIsFc10090 rigid:52SknklRfjlIec1zaBSbMFbc8VU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K4J6 uniprotkb:Q9Z0S2 intact:EBI-8291665|intact:UNK-5521183|uniprotkb:Q642U1|ensembl:ENSMUSP00000105207 intact:EBI-26669558|ensembl:ENSMUSP00000000253 psi-mi:mrtfa_mouse(display_long)|uniprotkb:Mrtfa(gene name)|psi-mi:Mrtfa(display_short)|uniprotkb:Basic SAP coiled-coil transcription activator(gene name synonym)|uniprotkb:Bsac(gene name synonym)|uniprotkb:MKL/myocardin-like protein 1(gene name synonym)|uniprotkb:Mal(gene name synonym)|uniprotkb:Megakaryoblastic leukemia 1 protein homolog(gene name synonym)|uniprotkb:Megakaryocytic acute leukemia protein homolog(gene name synonym)|uniprotkb:Mkl1(gene name synonym) psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674326|imex:IM-28774-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076005.1|refseq:NP_694629.2|dip:DIP-60884N|ensembl:ENSMUSG00000042292(gene)|ensembl:ENSMUST00000109579(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001764"(neuron migration)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR029992|interpro:IPR036361|interpro:IPR043451|mint:Q8K4J6|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2YJE|rcsb pdb:2YJF|reactome:R-MMU-3899300|reactome:R-MMU-5663220|go:"GO:0005829"(cytosol)|entrezgene/locuslink:223701(identity) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) - comment:mint|function:"Transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JllEBRX54Z25+MAvSfRzjCaaQ5810090 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rigid:vsQ4yooNjoYEbRihyqsdmMXC7NY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48281 uniprotkb:Q04742 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674318|imex:IM-28774-1127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791|entrezgene/locuslink:22337(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:KjPqbRmuI+0FvOwLpZIROF4oZSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6J1H4 uniprotkb:Q6J1H4 intact:EBI-26674289|ensembl:ENSMUSP00000128848|uniprotkb:O70530 intact:EBI-26674289|ensembl:ENSMUSP00000128848|uniprotkb:O70530 psi-mi:utf1_mouse(display_long)|uniprotkb:Utf1(gene name)|psi-mi:Utf1(display_short) psi-mi:utf1_mouse(display_long)|uniprotkb:Utf1(gene name)|psi-mi:Utf1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674302|imex:IM-28774-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000047751(gene)|ensembl:ENSMUST00000168457(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071837"(HMG box domain binding)|interpro:IPR044822|refseq:NP_033508.1|entrezgene/locuslink:22286(identity) ensembl:ENSMUSG00000047751(gene)|ensembl:ENSMUST00000168457(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071837"(HMG box domain binding)|interpro:IPR044822|refseq:NP_033508.1|entrezgene/locuslink:22286(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bvIr2AbzOgAEvm+W0gCwT6cis1k10090 rogid:bvIr2AbzOgAEvm+W0gCwT6cis1k10090 rigid:FEAJxo6IEhw3a4zfqVueNd1h3Ek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60644 uniprotkb:P28705 intact:EBI-5276809|ensembl:ENSMUSP00000073188|ensembl:ENSMUSP00000103545|ensembl:ENSMUSP00000126788 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 psi-mi:nr1h2_mouse(display_long)|uniprotkb:Nr1h2(gene name)|psi-mi:Nr1h2(display_short)|uniprotkb:Lxrb(gene name synonym)|uniprotkb:Rip15(gene name synonym)|uniprotkb:Unr(gene name synonym)|uniprotkb:Unr2(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein No.15(gene name synonym)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym) psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674281|imex:IM-28774-2033 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272446.1|refseq:NP_001272447.1|refseq:NP_001272448.1|refseq:NP_033499.1|refseq:XP_006540867.1|dip:DIP-444N|ensembl:ENSMUSG00000060601(gene)|ensembl:ENSMUST00000073488(transcript)|ensembl:ENSMUST00000107912(transcript)|ensembl:ENSMUST00000167197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0046965"(retinoid X receptor binding)|reactome:R-MMU-8866427|reactome:R-MMU-9029569|reactome:R-MMU-9623433|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|reactome:R-MMU-383280|reactome:R-MMU-4090294|entrezgene/locuslink:22260(identity) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XSR7ZWDbMQj6uwWVWI++0pr0Eq810090 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rigid:vgXtVVHuWGq9vegKon3fLajbxJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0Y9 uniprotkb:P28705 intact:EBI-5276764|uniprotkb:Q9QUH7|ensembl:ENSMUSP00000002177|ensembl:ENSMUSP00000106986|ensembl:ENSMUSP00000106988 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 psi-mi:nr1h3_mouse(display_long)|uniprotkb:Nr1h3(gene name)|psi-mi:Nr1h3(display_short)|uniprotkb:Lxra(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym) psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674273|imex:IM-28774-2453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171201.1|refseq:NP_038867.2|refseq:XP_006499229.1|refseq:XP_006499230.1|refseq:XP_006499231.1|dip:DIP-62095N|rcsb pdb:3FAL|rcsb pdb:3FC6|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-8866427|reactome:R-MMU-9029569|reactome:R-MMU-9623433|ensembl:ENSMUSG00000002108(gene)|ensembl:ENSMUST00000002177(transcript)|ensembl:ENSMUST00000111354(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|ensembl:ENSMUST00000111356(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|rcsb pdb:2ACL|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:22259(identity) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:plRi02INEW/CTelVP1it9J2FWAE10090 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rigid:4kIx780aabTfzaNaF1+Fe22ARMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0Y9 uniprotkb:P28705 intact:EBI-5276764|uniprotkb:Q9QUH7|ensembl:ENSMUSP00000002177|ensembl:ENSMUSP00000106986|ensembl:ENSMUSP00000106988 intact:EBI-26667754|ensembl:ENSMUSP00000015987|ensembl:ENSMUSP00000107015|ensembl:ENSMUSP00000107017 psi-mi:nr1h3_mouse(display_long)|uniprotkb:Nr1h3(gene name)|psi-mi:Nr1h3(display_short)|uniprotkb:Lxra(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym) psi-mi:rxrg_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Rxrg(gene name)|psi-mi:Rxrg(display_short)|uniprotkb:Nr2b3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674265|imex:IM-28774-2031 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171201.1|refseq:NP_038867.2|refseq:XP_006499229.1|refseq:XP_006499230.1|refseq:XP_006499231.1|dip:DIP-62095N|rcsb pdb:3FAL|rcsb pdb:3FC6|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-8866427|reactome:R-MMU-9029569|reactome:R-MMU-9623433|ensembl:ENSMUSG00000002108(gene)|ensembl:ENSMUST00000002177(transcript)|ensembl:ENSMUST00000111354(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|ensembl:ENSMUST00000111356(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|rcsb pdb:2ACL|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:22259(identity) reactome:R-MMU-5362517|ensembl:ENSMUSG00000015843(gene)|ensembl:ENSMUST00000015987(transcript)|ensembl:ENSMUST00000111384(transcript)|ensembl:ENSMUST00000111386(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|reactome:R-MMU-383280|refseq:NP_001153203.1|refseq:NP_033133.1|entrezgene/locuslink:20183(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:plRi02INEW/CTelVP1it9J2FWAE10090 rogid:aXOYgzj9t8RbmgRvGzhbib8vEL410090 rigid:4kIx780aabTfzaNaF1+Fe22ARMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0Y9 uniprotkb:P28700 intact:EBI-5276764|uniprotkb:Q9QUH7|ensembl:ENSMUSP00000002177|ensembl:ENSMUSP00000106986|ensembl:ENSMUSP00000106988 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:nr1h3_mouse(display_long)|uniprotkb:Nr1h3(gene name)|psi-mi:Nr1h3(display_short)|uniprotkb:Lxra(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674257|imex:IM-28774-2029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171201.1|refseq:NP_038867.2|refseq:XP_006499229.1|refseq:XP_006499230.1|refseq:XP_006499231.1|dip:DIP-62095N|rcsb pdb:3FAL|rcsb pdb:3FC6|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-8866427|reactome:R-MMU-9029569|reactome:R-MMU-9623433|ensembl:ENSMUSG00000002108(gene)|ensembl:ENSMUST00000002177(transcript)|ensembl:ENSMUST00000111354(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|ensembl:ENSMUST00000111356(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|rcsb pdb:2ACL|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:22259(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|entrezgene/locuslink:20181(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:plRi02INEW/CTelVP1it9J2FWAE10090 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 rigid:e/6UaSw2PgI7811gCcZuv7F5r5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0Y9 uniprotkb:P28700 intact:EBI-5276764|uniprotkb:Q9QUH7|ensembl:ENSMUSP00000002177|ensembl:ENSMUSP00000106986|ensembl:ENSMUSP00000106988 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:nr1h3_mouse(display_long)|uniprotkb:Nr1h3(gene name)|psi-mi:Nr1h3(display_short)|uniprotkb:Lxra(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674249|imex:IM-28774-1561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171201.1|refseq:NP_038867.2|refseq:XP_006499229.1|refseq:XP_006499230.1|refseq:XP_006499231.1|dip:DIP-62095N|rcsb pdb:3FAL|rcsb pdb:3FC6|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-8866427|reactome:R-MMU-9029569|reactome:R-MMU-9623433|ensembl:ENSMUSG00000002108(gene)|ensembl:ENSMUST00000002177(transcript)|ensembl:ENSMUST00000111354(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|ensembl:ENSMUST00000111356(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|rcsb pdb:2ACL|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:22259(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|entrezgene/locuslink:20181(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:plRi02INEW/CTelVP1it9J2FWAE10090 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 rigid:e/6UaSw2PgI7811gCcZuv7F5r5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q811S7 uniprotkb:Q07279 intact:EBI-5710174|uniprotkb:A4QPG4|uniprotkb:Q3UPR3|uniprotkb:Q3US11|uniprotkb:Q60786|uniprotkb:Q8C514|ensembl:ENSMUSP00000081946|ensembl:ENSMUSP00000150023 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:ubip1_mouse(display_long)|uniprotkb:Ubp1(gene name)|psi-mi:Ubp1(display_short)|uniprotkb:Cp2b(gene name synonym)|uniprotkb:Nf2d9(gene name synonym)|uniprotkb:Nuclear factor 2d9(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674241|imex:IM-28774-1125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076788.1|refseq:NP_038727.1|refseq:XP_006512114.2|refseq:XP_006512117.2|ensembl:ENSMUSG00000009741(gene)|ensembl:ENSMUST00000084885(transcript)|ensembl:ENSMUST00000216558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q811S7|entrezgene/locuslink:22221(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Nt11E5Wv/MovMgjsl1GUvjXxz8Y10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:OdEt0iIid+gwREHaW2NINB8AP2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q811S7 uniprotkb:Q61545 intact:EBI-5710174|uniprotkb:A4QPG4|uniprotkb:Q3UPR3|uniprotkb:Q3US11|uniprotkb:Q60786|uniprotkb:Q8C514|ensembl:ENSMUSP00000081946|ensembl:ENSMUSP00000150023 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:ubip1_mouse(display_long)|uniprotkb:Ubp1(gene name)|psi-mi:Ubp1(display_short)|uniprotkb:Cp2b(gene name synonym)|uniprotkb:Nf2d9(gene name synonym)|uniprotkb:Nuclear factor 2d9(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674233|imex:IM-28774-1559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076788.1|refseq:NP_038727.1|refseq:XP_006512114.2|refseq:XP_006512117.2|ensembl:ENSMUSG00000009741(gene)|ensembl:ENSMUST00000084885(transcript)|ensembl:ENSMUST00000216558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q811S7|entrezgene/locuslink:22221(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Nt11E5Wv/MovMgjsl1GUvjXxz8Y10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:BYwKgb5iO9JUYJ4/7cWicHNQ+Ck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IXZ3 uniprotkb:Q9NQ87 intact:EBI-11668057|uniprotkb:Q7Z615|uniprotkb:Q7Z616|uniprotkb:Q96MJ1|intact:EBI-28972363|ensembl:ENSP00000354482 intact:EBI-751092|uniprotkb:Q5TG99|intact:EBI-28984767|ensembl:ENSP00000361943 psi-mi:sp8_human(display_long)|uniprotkb:SP8(gene name)|psi-mi:SP8(display_short)|uniprotkb:Specificity protein 8(gene name synonym) psi-mi:heyl_human(display_long)|uniprotkb:Hairy-related transcription factor 3(gene name synonym)|uniprotkb:HEYL(gene name)|psi-mi:HEYL(display_short)|uniprotkb:HRT3(gene name synonym)|uniprotkb:BHLHB33(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 33(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674225|imex:IM-28774-1123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000354482|ensembl:ENST00000418710|ensembl:ENSP00000408792|refseq:NP_874359.2|refseq:NP_945194.1|ensembl:ENSG00000164651(gene)|ensembl:ENST00000361443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:221833(identity) refseq:NP_055386.1|ensembl:ENSP00000361943|ensembl:ENSG00000163909(gene)|ensembl:ENST00000372852(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0032835"(glomerulus development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050683"(AF-1 domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072014"(proximal tubule development)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-9013508|entrezgene/locuslink:26508(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xkc+ReBoy0M30uJ5lX6IAZuHEL09606 rogid:9cv/81nddMs9dyFA0lyOkjBCUXU9606 rigid:8c9nFSJ0lNY+QTQd2N9/ChD8GWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IXZ3 uniprotkb:Q8TB69 intact:EBI-11668057|uniprotkb:Q7Z615|uniprotkb:Q7Z616|uniprotkb:Q96MJ1|intact:EBI-28972363|ensembl:ENSP00000354482 intact:EBI-26674195|ensembl:ENSP00000464872 psi-mi:sp8_human(display_long)|uniprotkb:SP8(gene name)|psi-mi:SP8(display_short)|uniprotkb:Specificity protein 8(gene name synonym) psi-mi:zn519_human(display_long)|uniprotkb:ZNF519(gene name)|psi-mi:ZNF519(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674217|imex:IM-28774-2027 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000354482|ensembl:ENST00000418710|ensembl:ENSP00000408792|refseq:NP_874359.2|refseq:NP_945194.1|ensembl:ENSG00000164651(gene)|ensembl:ENST00000361443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:221833(identity) ensembl:ENSG00000175322(gene)|ensembl:ENST00000590202(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_660330.2|refseq:XP_016881051.1|refseq:XP_016881052.1|refseq:XP_016881053.1|refseq:XP_016881054.1|entrezgene/locuslink:162655(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xkc+ReBoy0M30uJ5lX6IAZuHEL09606 rogid:egcRrdbc10/Ju4kXhG+wYw40poE9606 rigid:JKuSkuTUfWXhmqUOJLNs7sJNj/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IXZ3 uniprotkb:Q14593 intact:EBI-11668057|uniprotkb:Q7Z615|uniprotkb:Q7Z616|uniprotkb:Q96MJ1|intact:EBI-28972363|ensembl:ENSP00000354482 intact:EBI-3922471|uniprotkb:Q6P3V4|uniprotkb:B3KQZ5|ensembl:ENSP00000418719 psi-mi:sp8_human(display_long)|uniprotkb:SP8(gene name)|psi-mi:SP8(display_short)|uniprotkb:Specificity protein 8(gene name synonym) psi-mi:zn273_human(display_long)|uniprotkb:ZNF273(gene name)|psi-mi:ZNF273(display_short)|uniprotkb:Zinc finger protein HZF9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674187|imex:IM-28774-1557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000354482|ensembl:ENST00000418710|ensembl:ENSP00000408792|refseq:NP_874359.2|refseq:NP_945194.1|ensembl:ENSG00000164651(gene)|ensembl:ENST00000361443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:221833(identity) refseq:NP_066971.2|ensembl:ENSG00000198039(gene)|ensembl:ENST00000476120(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:XP_016867177.1|refseq:XP_016867178.1|refseq:XP_016867179.1|refseq:XP_016867180.1|refseq:XP_016867181.1|refseq:XP_016867182.1|refseq:XP_016867183.1|refseq:XP_016867184.1|refseq:XP_016867185.1|refseq:XP_016867186.1|refseq:XP_016867187.1|entrezgene/locuslink:10793(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xkc+ReBoy0M30uJ5lX6IAZuHEL09606 rogid:epFz9E+oojXqrb+HO3/OwbjMztc9606 rigid:+CkO7Catlfxus70K5xa+DiIAXQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q8WUH1 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-11156883|ensembl:ENSP00000448050|ensembl:ENSP00000450165|ensembl:ENSP00000475473|uniprotkb:G3V214|uniprotkb:G3V1X3|uniprotkb:Q9H3K7|uniprotkb:B3KQ81 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:chur_human(display_long)|uniprotkb:CHURC1(gene name)|psi-mi:CHURC1(display_short)|uniprotkb:C14orf52(gene name synonym)|uniprotkb:CHCH(gene name synonym)|uniprotkb:My015(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674179|imex:IM-28774-2451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_001190992.1|refseq:NP_001190993.1|refseq:NP_660148.3|ensembl:ENSG00000258289(gene)|ensembl:ENST00000548752(transcript)|ensembl:ENST00000549115(transcript)|ensembl:ENST00000607599(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009508(Churchill)|interpro:IPR038543|mint:Q8WUH1|rcsb pdb:2JOX|entrezgene/locuslink:91612(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:WKqPPbQGe0cMce6ZEUDae229/jU9606 rigid:uhk3fQiN63dEzo4vuAzi6dccS1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q9H9D4 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674171|imex:IM-28774-1555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412|entrezgene/locuslink:79797(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rigid:RFCWkL+BZvhXqU4Yz3lDEyHmL2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P17027 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-5657766|uniprotkb:Q8NDP5|uniprotkb:Q96IT3|uniprotkb:Q9UG42|ensembl:ENSP00000349796|ensembl:ENSP00000377171|ensembl:ENSP00000387673 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:znf23_human(display_long)|uniprotkb:KOX16(gene name synonym)|uniprotkb:ZNF359(gene name synonym)|uniprotkb:ZNF612(gene name synonym)|uniprotkb:Zinc finger protein 359(gene name synonym)|uniprotkb:Zinc finger protein 612(gene name synonym)|uniprotkb:Zinc finger protein KOX16(gene name synonym)|uniprotkb:ZNF23(gene name)|psi-mi:ZNF23(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674163|imex:IM-28774-2025 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_001291421.1|refseq:NP_001291422.1|refseq:NP_001291423.1|refseq:NP_666016.1|ensembl:ENSG00000167377(gene)|ensembl:ENST00000357254(transcript)|ensembl:ENST00000393539(transcript)|ensembl:ENST00000428724(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P17027|reactome:R-HSA-212436|entrezgene/locuslink:7571(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:N5hIISReQVVo0kOTNVvoUS59+fk9606 rigid:z3pDExxaKA6FPjRxS9OVAWBRLxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P08048 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-12239601|ensembl:ENSP00000155093|ensembl:ENSP00000372525|uniprotkb:B4DVF7|uniprotkb:Q14021|uniprotkb:Q15558|uniprotkb:Q1RME9|uniprotkb:Q24JR0|uniprotkb:Q96TF3 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:zfy_human(display_long)|uniprotkb:ZFY(gene name)|psi-mi:ZFY(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674155|imex:IM-28774-2449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) ensembl:ENSG00000067646(gene)|ensembl:ENST00000155093(transcript)|ensembl:ENST00000383052(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:1KLR|rcsb pdb:1KLS|rcsb pdb:1XRZ|rcsb pdb:5ZNF|rcsb pdb:7ZNF|refseq:NP_001138747.1|refseq:NP_001138748.1|refseq:NP_003402.2|refseq:XP_005262627.1|refseq:XP_016885564.1|refseq:XP_016885566.1|entrezgene/locuslink:7544(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:kQk9T657oCkRymBzN2JQNffvM1U9606 rigid:Kb/weVNRDccGEfm+zj4XqqOD74U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q9NTW7 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674147|imex:IM-28774-3283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606 rigid:ZYxuVL9oW7GqC0wO8grFG57Sr+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q9C0G0 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-5654914|uniprotkb:Q9H8A1|uniprotkb:Q96MY0|uniprotkb:B5MD54|uniprotkb:Q9NXD7|uniprotkb:Q9NXD4|ensembl:ENSP00000299687 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:zn407_human(display_long)|uniprotkb:KIAA1703(gene name synonym)|uniprotkb:ZNF407(gene name)|psi-mi:ZNF407(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674139|imex:IM-28774-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:XP_011524372.1|refseq:XP_011524370.1|refseq:NP_001139661.1|refseq:NP_001139662.1|refseq:NP_060227.2|refseq:XP_005266783.1|ensembl:ENSG00000215421(gene)|ensembl:ENST00000299687(transcript)|interpro:IPR036236|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:55628(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:1IwRCT+v3qYg2Ii3jabVzznKu8Y9606 rigid:ryaimlMLTSaNI7AG2Pdd1+XJwjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P37231 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674131|imex:IM-28774-3281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:dEmvwRF8M9tEaWZCF117dFmnbh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P19838 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-300010|ensembl:ENSP00000378297|ensembl:ENSP00000424790|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|uniprotkb:A8K5Y5|uniprotkb:B3KVE8 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674123|imex:IM-28774-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-448706|ensembl:ENSG00000109320(gene)|ensembl:ENST00000394820(transcript)|ensembl:ENST00000505458(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1904385"(cellular response to angiotensin)|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|refseq:NP_001158884.1|refseq:NP_003989.2|refseq:NP_001306155.1|dip:DIP-106N|entrezgene/locuslink:4790(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606 rigid:ts3kbgUu17odZ0TvuornSen1rwE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P10244 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-1389468|uniprotkb:B2RBS5|uniprotkb:B7Z8D9|uniprotkb:F8W6N6|uniprotkb:Q53F07|ensembl:ENSP00000217026 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:mybb_human(display_long)|uniprotkb:Myb-like protein 2(gene name synonym)|uniprotkb:MYBL2(gene name)|psi-mi:MYBL2(display_short)|uniprotkb:BMYB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674115|imex:IM-28774-1121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_001265539.1|refseq:NP_002457.1|ensembl:ENSG00000101057(gene)|ensembl:ENST00000217026(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|mint:P10244|rcsb pdb:6C48|reactome:R-HSA-1362300|reactome:R-HSA-156711|reactome:R-HSA-8869496|entrezgene/locuslink:4605(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:2ldntN2B+u1fHcK4WPkL9UZYbzs9606 rigid:7R2vwNUXrQMCl12oOzmbwvLJ0eE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P29083 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674107|imex:IM-28774-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:lgCsN3BzQeIRHUYqNUqnqeiPM5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q96C00 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674099|imex:IM-28774-1553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rigid:9hmtt1gZd7acQ+Xee4kzxtqMwCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q8IYH5 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674091|imex:IM-28774-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:n/6t7p4HttCcftHjBNR4uSwBz34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q9Y2L8 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-2876965|intact:EBI-28975936|ensembl:ENSP00000322872|ensembl:ENSP00000377725|ensembl:ENSP00000392104|uniprotkb:A4D280|uniprotkb:D6W5S9 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:zksc5_human(display_long)|uniprotkb:ZKSCAN5(gene name)|psi-mi:ZKSCAN5(display_short)|uniprotkb:KIAA1015(gene name synonym)|uniprotkb:ZFP95(gene name synonym)|uniprotkb:Zinc finger protein 95 homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674083|imex:IM-28774-2857 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) ensembl:ENSG00000196652(gene)|ensembl:ENST00000326775(transcript)|ensembl:ENST00000394170(transcript)|ensembl:ENST00000451158(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q9Y2L8|rcsb pdb:2EM5|rcsb pdb:2EMM|rcsb pdb:2EMZ|rcsb pdb:2EN3|rcsb pdb:2EOM|rcsb pdb:2EON|rcsb pdb:2EOO|rcsb pdb:2YSO|rcsb pdb:2YTG|reactome:R-HSA-212436|go:"GO:0008270"(zinc ion binding)|ensembl:ENSP00000322872|ensembl:ENSP00000377725|ensembl:ENSP00000392104|refseq:NP_001305011.1|refseq:NP_001305012.1|refseq:NP_001305013.1|refseq:NP_055384.1|refseq:NP_659570.1|refseq:XP_016867407.1|refseq:XP_016867408.1|entrezgene/locuslink:23660(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:IGLnMrywMbMAwqoSnoXhPKm3Hus9606 rigid:zitYvqbX2z8qEmUVjbLFgyyRJTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:P09874 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674075|imex:IM-28774-1551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N|entrezgene/locuslink:142(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rigid:PHFcnWvPEd2h/+9aIK8HunlERno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C00 uniprotkb:Q86YN6 intact:EBI-395708|ensembl:ENSP00000378503|ensembl:ENSP00000413557|uniprotkb:A2AB19 intact:EBI-12522009|intact:EBI-28975181|uniprotkb:A2RUM8|uniprotkb:A2RUN0|uniprotkb:B3KVW0|uniprotkb:Q86YN3|uniprotkb:Q86YN4|uniprotkb:Q86YN5|uniprotkb:Q8N1N9|uniprotkb:Q8TDE4|uniprotkb:Q8TDE5|ensembl:ENSP00000312649 psi-mi:zbtb9_human(display_long)|uniprotkb:ZBTB9(gene name)|psi-mi:ZBTB9(display_short) psi-mi:prgc2_human(display_long)|uniprotkb:PPARGC1B(gene name)|psi-mi:PPARGC1B(display_short)|uniprotkb:PERC(gene name synonym)|uniprotkb:PGC-1-related estrogen receptor alpha coactivator(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1B(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674067|imex:IM-28774-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689948.1|ensembl:ENSG00000213588(gene)|ensembl:ENSG00000236515(gene)|ensembl:ENST00000395064(transcript)|ensembl:ENST00000414934(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0005634"(nucleus)|entrezgene/locuslink:221504(identity) ensembl:ENSP00000312649|ensembl:ENST00000360453|ensembl:ENSP00000353638|ensembl:ENST00000394320|ensembl:ENSP00000377855|ensembl:ENST00000403750|ensembl:ENSP00000384403|refseq:NP_001166169.1|refseq:NP_001166170.1|refseq:NP_573570.3|refseq:XP_005268429.1|ensembl:ENSG00000155846(gene)|ensembl:ENST00000309241(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0005654"(nucleoplasm)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979|rcsb pdb:3SP6|rcsb pdb:6D0Y|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-8939902|entrezgene/locuslink:133522(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UIcj7jbS1Y3sq56uH5XOBn8a8fs9606 rogid:CIBfI8+cR2bGhimtBQDrdSrYHsM9606 rigid:GprQYEnuS76xWH1MwRuREzVtcj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61187 uniprotkb:Q61187 intact:EBI-1202711|ensembl:ENSMUSP00000014546 intact:EBI-1202711|ensembl:ENSMUSP00000014546 psi-mi:ts101_mouse(display_long)|uniprotkb:Tsg101(gene name)|psi-mi:Tsg101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:ts101_mouse(display_long)|uniprotkb:Tsg101(gene name)|psi-mi:Tsg101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674051|imex:IM-28774-3279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068684.1|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|reactome:R-MMU-917729|ensembl:ENSMUSG00000014402(gene)|ensembl:ENSMUST00000014546(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:22088(identity) refseq:NP_068684.1|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|reactome:R-MMU-917729|ensembl:ENSMUSG00000014402(gene)|ensembl:ENSMUST00000014546(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:22088(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xaaLuoyhyn1UgchT9KTyD5FCTHg10090 rogid:xaaLuoyhyn1UgchT9KTyD5FCTHg10090 rigid:TAeERywuBX0cHWtvJr9ujHBKQhA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61187 uniprotkb:Q07279 intact:EBI-1202711|ensembl:ENSMUSP00000014546 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:ts101_mouse(display_long)|uniprotkb:Tsg101(gene name)|psi-mi:Tsg101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674043|imex:IM-28774-1117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068684.1|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|reactome:R-MMU-917729|ensembl:ENSMUSG00000014402(gene)|ensembl:ENSMUST00000014546(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:22088(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xaaLuoyhyn1UgchT9KTyD5FCTHg10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:z0P/YhHvI/WStoPcmitf38hE6cA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K119 uniprotkb:Q61545 intact:EBI-26674552|ensembl:ENSMUSP00000027267 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:q8k119_mouse(display_long)|uniprotkb:Pms1(gene name)|psi-mi:Pms1(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674582|imex:IM-28774-3287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026098(gene)|ensembl:ENSMUST00000027267(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|refseq:NP_705784.1|refseq:XP_006496001.1|refseq:XP_006496002.1|refseq:XP_006496004.1|refseq:XP_006496005.1|refseq:XP_011236799.1|entrezgene/locuslink:227099(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K7sxd6XP6t5Q24XOLrTlsRcQgo810090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:j0iupWf7EW4RdAmcNfTo9jxiqxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81183 uniprotkb:P48972 intact:EBI-11361200|uniprotkb:Q8C8A3|ensembl:ENSMUSP00000027146 intact:EBI-5738119|ensembl:ENSMUSP00000018005 psi-mi:ikzf2_mouse(display_long)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym)|uniprotkb:Ikzf2(gene name)|psi-mi:Ikzf2(display_short)|uniprotkb:Helios(gene name synonym)|uniprotkb:Zfpn1a2(gene name synonym)|uniprotkb:Znfn1a2(gene name synonym) psi-mi:mybb_mouse(display_long)|uniprotkb:Mybl2(gene name)|psi-mi:Mybl2(display_short)|uniprotkb:Bmyb(gene name synonym)|uniprotkb:Myb-like protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674648|imex:IM-28774-2039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035900.2|refseq:XP_006496029.1|refseq:XP_006496030.1|ensembl:ENSMUSG00000025997(gene)|ensembl:ENSMUST00000027146(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_017175888.1|entrezgene/locuslink:22779(identity) refseq:NP_032678.1|ensembl:ENSMUSG00000017861(gene)|ensembl:ENSMUST00000018005(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|rcsb pdb:2D9A|entrezgene/locuslink:17865(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:R7rnvAez1QlgHYV/iR1r3kjreEY10090 rogid:2R9Q8v7s40AR3teOYrd7/+/2GaQ10090 rigid:GQ2K16EjJFGNr/50VlfDK3mVidg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BP86 uniprotkb:Q61545 intact:EBI-26674606|uniprotkb:Q6PGG7|uniprotkb:Q80UG9|uniprotkb:Q810L1 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:snpc4_mouse(display_long)|uniprotkb:snRNA-activating protein complex 190 kDa subunit(gene name synonym)|uniprotkb:Snapc4(gene name)|psi-mi:Snapc4(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674632|imex:IM-28774-2865 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|interpro:IPR017884|refseq:NP_001277348.1|refseq:NP_758842.1|reactome:R-MMU-6807505|reactome:R-MMU-76071|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR001005(SANT, DNA-binding)|entrezgene/locuslink:227644(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:egb8LUGBtOWQzZqyBNYQ4bzRMFU10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:J1XPNF/IGzdMz7H6AKBDw/32QD4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:Q8BP86 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-26674606|uniprotkb:Q6PGG7|uniprotkb:Q80UG9|uniprotkb:Q810L1 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:snpc4_mouse(display_long)|uniprotkb:snRNA-activating protein complex 190 kDa subunit(gene name synonym)|uniprotkb:Snapc4(gene name)|psi-mi:Snapc4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674640|imex:IM-28774-1129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|interpro:IPR017884|refseq:NP_001277348.1|refseq:NP_758842.1|reactome:R-MMU-6807505|reactome:R-MMU-76071|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR001005(SANT, DNA-binding)|entrezgene/locuslink:227644(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:egb8LUGBtOWQzZqyBNYQ4bzRMFU10090 rigid:HNr9ZdrBNouKz3K7CfqDXeOaJiY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GD3 uniprotkb:Q01844 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675000|imex:IM-28774-2871 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1|entrezgene/locuslink:22955(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:EpDsRqtf3qWbBhahuR3xOemSEtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GD3 uniprotkb:P61457 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675008|imex:IM-28774-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1|entrezgene/locuslink:22955(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:edzdI5d4hskRiywvm7NBTbCqQvM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13573 uniprotkb:Q9Y6K9 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674984|imex:IM-28774-2869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N|entrezgene/locuslink:22938(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:KqiHlzi1SPq7VNT8bxgmkYePyUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:Q9D2H6 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26674949|uniprotkb:Q6A0E1 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:sp2_mouse(display_long)|uniprotkb:Sp2(gene name)|psi-mi:Sp2(display_short)|uniprotkb:Kiaa0048(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674976|imex:IM-28774-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072359"(circulatory system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_001074433.1|refseq:NP_084496.2|interpro:IPR030451|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:78912(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:UcPZ7bur3a/CDkDAeAP1GvD5Pvg10090 rigid:NJ4Vqg9eQiVRMuaYP4UChH1J8wM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:Q9WTP9 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26674907|ensembl:ENSMUSP00000035976 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:vax2_mouse(display_long)|uniprotkb:Ventral retina homeodomain protein(gene name synonym)|uniprotkb:Vax2(gene name)|psi-mi:Vax2(display_short)|uniprotkb:Vex(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674941|imex:IM-28774-1567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) ensembl:ENSMUSG00000034777(gene)|ensembl:ENSMUST00000037807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033021|go:"GO:0043010"(camera-type eye development)|refseq:NP_036042.1|entrezgene/locuslink:24113(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:gyaEel7JgrCB8jlzkvFdzD+fZBU10090 rigid:OZaMD9hYXTLVOaFr/emONRnPXz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:O35426 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26674782|ensembl:ENSMUSP00000054852|uniprotkb:Q8VHM0|uniprotkb:Q922G5|uniprotkb:Q9ESS3 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:xbp1_mouse(display_long)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym)|uniprotkb:Xbp1(gene name)|psi-mi:Xbp1(display_short)|uniprotkb:Treb5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674899|imex:IM-28774-1131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060096"(serotonin secretion, neurotransmission)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060691"(epithelial cell maturation involved in salivary gland development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0098793"(presynapse)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|ensembl:ENSMUSG00000020484(gene)|ensembl:ENSMUST00000063084(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|refseq:NP_001258659.1|refseq:NP_038870.2|entrezgene/locuslink:22433(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:iqVkEr46TAmwNCsJ4HShqw6I5vc10090 rigid:wKarp0fiWPtVFZvO9KPNjUgS0Sg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:Q811S7 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-5710174|uniprotkb:A4QPG4|uniprotkb:Q3UPR3|uniprotkb:Q3US11|uniprotkb:Q60786|uniprotkb:Q8C514|ensembl:ENSMUSP00000081946|ensembl:ENSMUSP00000150023 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:ubip1_mouse(display_long)|uniprotkb:Ubp1(gene name)|psi-mi:Ubp1(display_short)|uniprotkb:Cp2b(gene name synonym)|uniprotkb:Nf2d9(gene name synonym)|uniprotkb:Nuclear factor 2d9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674774|imex:IM-28774-2867 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) refseq:NP_001076788.1|refseq:NP_038727.1|refseq:XP_006512114.2|refseq:XP_006512117.2|ensembl:ENSMUSG00000009741(gene)|ensembl:ENSMUST00000084885(transcript)|ensembl:ENSMUST00000216558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q811S7|entrezgene/locuslink:22221(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:Nt11E5Wv/MovMgjsl1GUvjXxz8Y10090 rigid:YFdK3cZgsN9r9p49aIDv7krkjNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:P70700 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26672187|ensembl:ENSMUSP00000099494|uniprotkb:Q3UMX7 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:rpa2_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym)|uniprotkb:Polr1b(gene name)|psi-mi:Polr1b(display_short)|uniprotkb:Rpa2(gene name synonym)|uniprotkb:Rpo1-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674766|imex:IM-28774-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) ensembl:ENSMUSG00000027395(gene)|ensembl:ENSMUST00000103205(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0007566"(embryo implantation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0014029"(neural crest formation)|go:"GO:0017126"(nucleologenesis)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|reactome:R-MMU-5250924|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|refseq:NP_033112.2|entrezgene/locuslink:20017(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:xfiED4Nca+YAmqV5SXedNnIKQY010090 rigid:vAcPyc/iHrAdVMYKym9t892442c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:P25799 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674758|imex:IM-28774-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:41acR/1l6374+54juNcT0kQBIf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:P97311 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-457132|uniprotkb:Q80YQ7|ensembl:ENSMUSP00000027601 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:mcm6_mouse(display_long)|uniprotkb:Mis5 homolog(gene name synonym)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:Mcmd6(gene name synonym)|uniprotkb:Mis5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674750|imex:IM-28774-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) refseq:NP_032593.1|ensembl:ENSMUSG00000026355(gene)|ensembl:ENSMUST00000027601(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|mint:P97311|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052|entrezgene/locuslink:17219(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:JwuQj25XyutAyROxAkOr/NyIjCA10090 rigid:8EVtoLsQYfpRe6p2KC7V4Yx32YY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:Q9Z0S2 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26669558|ensembl:ENSMUSP00000000253 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674742|imex:IM-28774-2465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rigid:LtlVpSteoNes1mtXOPTwMX3GdDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:Q8CCE9 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-7450874|uniprotkb:Q6IR08|intact:MINT-4979074|uniprotkb:Q62065|uniprotkb:Q9QY56|uniprotkb:Q6PGI1|uniprotkb:Q3UNJ9|uniprotkb:Q05BH7 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:e4f1_mouse(display_long)|uniprotkb:E4F transcription factor 1(gene name synonym)|uniprotkb:Putative E3 ubiquitin-protein ligase E4F1(gene name synonym)|uniprotkb:Transcription factor E4F(gene name synonym)|uniprotkb:Transcription factor phi AP3(gene name synonym)|uniprotkb:p120E4F(gene name synonym)|uniprotkb:E4f1(gene name)|psi-mi:E4f1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase E4F1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674734|imex:IM-28774-1565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) refseq:XP_011244570.1|refseq:NP_001288713.1|mint:Q8CCE9|interpro:IPR036236|refseq:NP_031919.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006260"(DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|entrezgene/locuslink:13560(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:a0EPaeWXcFlLScLgeeeuixQ960Y10090 rigid:5MCDC6Sp9zXAa6hMk013x/FYF3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:Q640N1 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26670419|ensembl:ENSMUSP00000099987|uniprotkb:O88442|uniprotkb:Q3TVV5|uniprotkb:Q3TWA7|uniprotkb:Q3TX56|uniprotkb:Q3TXB2|uniprotkb:Q5NCI9|uniprotkb:Q61281 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:aebp1_mouse(display_long)|uniprotkb:Aortic carboxypeptidase-like protein(gene name synonym)|uniprotkb:Aebp1(gene name)|psi-mi:Aebp1(display_short)|uniprotkb:Aclp(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674726|imex:IM-28774-2045 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) ensembl:ENSMUSG00000020473(gene)|ensembl:ENSMUST00000102923(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:1904026"(regulation of collagen fibril organization)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR008979(Galactose-binding like)|refseq:NP_001278786.1|refseq:NP_033766.2|entrezgene/locuslink:11568(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:QVnPQgzue6oKrevbBCdvlgr8dO010090 rigid:dH75yTBWdkRWRBCmS7dD+6af4hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2K1 uniprotkb:Q8N653 intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674718|imex:IM-28774-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:FW/fZMxT3sHVRSFIsX2i8EK1Sag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2K1 uniprotkb:P24278 intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911 intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746 psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short) psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674710|imex:IM-28774-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity) refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606 rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606 rigid:MLdjmlB+MP56AIoSPUt0YdjRBKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2K1 uniprotkb:Q01844 intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674702|imex:IM-28774-2463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:0O8elAV5mHVMVgKJydDwV0eEn0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91W39 uniprotkb:Q60749 intact:EBI-8329509|uniprotkb:A2A5L2|intact:MINT-4103204|ensembl:ENSMUSP00000046388 intact:EBI-519077|uniprotkb:A2ACH3|uniprotkb:Q7M4N5|uniprotkb:Q3U8T3|uniprotkb:Q60735|uniprotkb:Q99M33|ensembl:ENSMUSP00000066516|ensembl:ENSMUSP00000115402|uniprotkb:B2KG38 psi-mi:ncoa5_mouse(display_long)|uniprotkb:Ncoa5(gene name)|psi-mi:Ncoa5(display_short)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:khdr1_mouse(display_long)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:Khdrbs1(gene name)|psi-mi:Khdrbs1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674694|imex:IM-28774-2043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659141.1|ensembl:ENSMUSG00000039804(gene)|ensembl:ENSMUST00000040381(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q91W39|entrezgene/locuslink:228869(identity) ensembl:ENSMUSG00000028790(gene)|ensembl:ENSMUST00000066257(transcript)|ensembl:ENSMUST00000129342(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q60749|reactome:R-MMU-8849468|refseq:NP_035447.3|dip:DIP-2861N|entrezgene/locuslink:20218(identity) - comment:mint|function:"Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2)" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wPwJKZRExN0LsGR8FyKm74oUm2g10090 rogid:FtKudvPZeoFATHi0fUbnPsJgons10090 rigid:95KKIGJ72pi7DsINXFV2JGTHRUU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y483 uniprotkb:P16220 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674686|imex:IM-28774-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|entrezgene/locuslink:22823(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:G68F5MsqPvKjOxiG2t/31tWP0Ws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2D1 uniprotkb:P53567 intact:EBI-492509|uniprotkb:Q9BSA1|uniprotkb:Q9UNQ3|uniprotkb:B3KND3|ensembl:ENSP00000396954|ensembl:ENSP00000470633 intact:EBI-740209|uniprotkb:Q5U052|ensembl:ENSP00000284000|ensembl:ENSP00000466022|ensembl:ENSP00000499062|uniprotkb:B2R946 psi-mi:atf5_human(display_long)|uniprotkb:Activating transcription factor 5(gene name synonym)|uniprotkb:Transcription factor ATFx(gene name synonym)|uniprotkb:ATF5(gene name)|psi-mi:ATF5(display_short)|uniprotkb:ATFX(gene name synonym) psi-mi:cebpg_human(display_long)|uniprotkb:CEBPG(gene name)|psi-mi:CEBPG(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674678|imex:IM-28774-2041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277675.1|ensembl:ENSP00000396954|ensembl:ENSP00000470633|refseq:NP_001180575.1|refseq:NP_036200.2|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0015631"(tubulin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029855|reactome:R-HSA-9648895|go:"GO:0003700"(DNA-binding transcription factor activity)|ensembl:ENSG00000169136(gene)|ensembl:ENST00000423777(transcript)|ensembl:ENST00000595125(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|refseq:XP_011524931.1|entrezgene/locuslink:22809(identity) go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|ensembl:ENSG00000153879(gene)|ensembl:ENST00000284000(transcript)|ensembl:ENST00000585933(transcript)|ensembl:ENST00000652630(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001797.1|refseq:NP_001239225.1|entrezgene/locuslink:1054(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A8Cxm5wbXjpIYscQEsveFMUoV8c9606 rogid:UneEv6RijykMEaPgr/apEUYxnJI9606 rigid:cVi8VmuPZxg+od0E/gqrMa9cuAo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GD3 uniprotkb:Q8N653 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675016|imex:IM-28774-1133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1|entrezgene/locuslink:22955(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:M5G+BGm4ZJQg0dV5pGY6jj/q9MU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3TVI8 uniprotkb:Q9CQI9 intact:EBI-646316|uniprotkb:Q3TD91|uniprotkb:Q3TWL9|uniprotkb:Q8R319|ensembl:ENSMUSP00000040429 intact:EBI-309220|ensembl:ENSMUSP00000042204 psi-mi:pbip1_mouse(display_long)|uniprotkb:Hpip(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)|uniprotkb:Pbxip1(gene name)|psi-mi:Pbxip1(display_short) psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26674992|imex:IM-28774-2047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666243.1|refseq:XP_006501416.1|ensembl:ENSMUSG00000042613(gene)|ensembl:ENSMUST00000038942(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0010467"(gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q3TVI8|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:229534(identity) refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436|entrezgene/locuslink:69790(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:r8Dc/6AM2ygzAfQpzi1zK9vOvow10090 rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090 rigid:HSOsQMxGi1dfE+KDZASQSJ7l5Hw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5X4 uniprotkb:O43251 intact:EBI-7216962|uniprotkb:Q9UHM4|intact:MINT-4302911|ensembl:ENSP00000482504|uniprotkb:B6ZGU0 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:nr2e3_human(display_long)|uniprotkb:NR2E3(gene name)|psi-mi:NR2E3(display_short)|uniprotkb:PNR(gene name synonym)|uniprotkb:RNR(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group E member 3(gene name synonym)|uniprotkb:Retina-specific nuclear receptor(gene name synonym) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675265|imex:IM-28774-3301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055064.1|refseq:NP_057430.1|go:"GO:0007601"(visual perception)|go:"GO:0030154"(cell differentiation)|go:"GO:0007602"(phototransduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:4LOG|reactome:R-HSA-383280|ensembl:ENSG00000278570(gene)|ensembl:ENST00000617575(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|entrezgene/locuslink:10002(identity) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) - comment:mint|function:Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function|function:"Defects in NR2E3 are a cause of enhanced S cone syndrome (ESCS) [MIM:268100]. ESCS is an autosomal recessive retinopathy in which patients have increased sensitivity to blue light; perception of blue light is mediated by what is normally the least populous cone photoreceptor subtype, the S (short wavelength, blue) cones. ESCS is also associated with visual loss, with night blindness occurring from early in life, varying degrees of L (long, red)- and M (middle, green)-cone vision, and retinal degeneration"|function:"Defects in NR2E3 are the cause of retinitis pigmentosa type 37 (RP37) [MIM:611131]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP37 inheritance is autosomal dominant" - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iasn0OPCQKevrxi5GFbB9ZjRmbI9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:Fah4oqXilL+E5h3spnDu/V5d0Hk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91W50 uniprotkb:P09027 intact:EBI-8318466|intact:MINT-4121285|ensembl:ENSMUSP00000029446|ensembl:ENSMUSP00000143503 intact:EBI-26667584|ensembl:ENSMUSP00000044809|ensembl:ENSMUSP00000107613|ensembl:ENSMUSP00000107614|uniprotkb:Q3UUD3 psi-mi:csde1_mouse(display_long)|uniprotkb:Csde1(gene name)|psi-mi:Csde1(display_short)|uniprotkb:D3Jfr1(gene name synonym) psi-mi:hxd3_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.1(gene name synonym)|uniprotkb:Homeobox protein MH-19(gene name synonym)|uniprotkb:Hoxd3(gene name)|psi-mi:Hoxd3(display_short)|uniprotkb:Hox-4.1(gene name synonym)|uniprotkb:Hoxd-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675024|imex:IM-28774-2049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659150.1|refseq:XP_017175039.1|ensembl:ENSMUSG00000068823(gene)|ensembl:ENSMUST00000029446(transcript)|ensembl:ENSMUST00000197827(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|interpro:IPR024642|mint:Q91W50|entrezgene/locuslink:229663(identity) ensembl:ENSMUSG00000079277(gene)|ensembl:ENSMUST00000047830(transcript)|ensembl:ENSMUST00000111982(transcript)|ensembl:ENSMUST00000111983(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|go:"GO:0051216"(cartilage development)|refseq:NP_034598.2|entrezgene/locuslink:15434(identity) - comment:mint|function:"RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BLYLjo9V0qtWfPeN4Ke6JFZxWAQ10090 rogid:o47Zd1IWzICvHRhhGN4cN2AQ+r010090 rigid:93RTiEJIVno+zYgLu4U9dd0P/P4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15022 uniprotkb:P16220 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675249|imex:IM-28774-2467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|entrezgene/locuslink:23512(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:JKu3Gw2tk1yGOKFHlcb2Pf21HFU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VCD5 uniprotkb:Q60953 intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675241|imex:IM-28774-1573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N|entrezgene/locuslink:234959(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RphTDePi36YqZFcRmkcobUnPd7I10090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:FROh4cUI/CXzTLTjt9XUayHNtVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VCD5 uniprotkb:Q04744 intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411 intact:EBI-26673795|ensembl:ENSMUSP00000053361|uniprotkb:G3X9A6|uniprotkb:Q80UE7 psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym) psi-mi:emx2_mouse(display_long)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym)|uniprotkb:Emx2(gene name)|psi-mi:Emx2(display_short)|uniprotkb:Emx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675233|imex:IM-28774-3299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N|entrezgene/locuslink:234959(identity) ensembl:ENSMUSG00000043969(gene)|ensembl:ENSMUST00000062216(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034262.2|entrezgene/locuslink:13797(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:RphTDePi36YqZFcRmkcobUnPd7I10090 rogid:K3i+Zeai93MikBwJdzf940evg0I10090 rigid:nU81uoXBouR+4kIxsJ7fV7LnZ0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95503 uniprotkb:P31274 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675225|imex:IM-28774-2881 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|entrezgene/locuslink:23466(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:iq9VZ1JqoprWXNKVPyjfIktyapI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:E9QAP1 uniprotkb:P56477 intact:EBI-26675192|ensembl:ENSMUSP00000052944 intact:EBI-643408|ensembl:ENSMUSP00000004392|ensembl:ENSMUSP00000127021 psi-mi:e9qap1_mouse(display_long)|uniprotkb:Zfp764(gene name)|psi-mi:Zfp764(display_short) psi-mi:irf5_mouse(display_long)|uniprotkb:Irf5(gene name)|psi-mi:Irf5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675217|imex:IM-28774-3297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045757(gene)|ensembl:ENSMUST00000059199(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_666315.3|entrezgene/locuslink:233893(identity) refseq:NP_036187.1|refseq:NP_001239311.1|refseq:XP_006505160.1|ensembl:ENSMUSG00000029771(gene)|ensembl:ENSMUST00000004392(transcript)|ensembl:ENSMUST00000163511(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|dip:DIP-49382N|entrezgene/locuslink:27056(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VMvJ2juqoWs+6uPSK3Qnkv3ApSI10090 rogid:Mdz1n0MUvYYjxamfbVAzdusN1M810090 rigid:jqjQ8HOc97rolD1Gu0n30VU1pKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:E9QAP1 uniprotkb:Q07279 intact:EBI-26675192|ensembl:ENSMUSP00000052944 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:e9qap1_mouse(display_long)|uniprotkb:Zfp764(gene name)|psi-mi:Zfp764(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675209|imex:IM-28774-2879 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045757(gene)|ensembl:ENSMUST00000059199(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_666315.3|entrezgene/locuslink:233893(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VMvJ2juqoWs+6uPSK3Qnkv3ApSI10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:ofe55Hzg6PatvQBr/qFQYOXu2iw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0T2 uniprotkb:Q9CWW7 intact:EBI-644020|ensembl:ENSMUSP00000055374 intact:EBI-11057018|ensembl:ENSMUSP00000025444 psi-mi:zn768_mouse(display_long)|uniprotkb:Znf768(gene name)|psi-mi:Znf768(display_short)|uniprotkb:Zfp768(gene name synonym) psi-mi:cxxc1_mouse(display_long)|uniprotkb:Cxxc1(gene name)|psi-mi:Cxxc1(display_short)|uniprotkb:Cgbp(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:Pccx1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675184|imex:IM-28774-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666314.1|reactome:R-MMU-212436|ensembl:ENSMUST00000060783(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSMUSG00000047371(gene)|entrezgene/locuslink:233890(identity) refseq:NP_083144.1|ensembl:ENSMUSG00000024560(gene)|ensembl:ENSMUST00000025444(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR022056|interpro:IPR037869|entrezgene/locuslink:74322(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bTUdW3fkPL/cBbA+jzd78iNMw4c10090 rogid:F8l4yKXUMeRz4IzsTFgLRlA3I7E10090 rigid:3ZV3fvUxL1LnsDbsd6n2F2qxslU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0T2 uniprotkb:Q8CF60 intact:EBI-644020|ensembl:ENSMUSP00000055374 intact:EBI-16726479|ensembl:ENSMUSP00000023176|uniprotkb:E9PXW0|uniprotkb:Q7TMI6|uniprotkb:Q8K439 psi-mi:zn768_mouse(display_long)|uniprotkb:Znf768(gene name)|psi-mi:Znf768(display_short)|uniprotkb:Zfp768(gene name synonym) psi-mi:zn263_mouse(display_long)|uniprotkb:Znf263(gene name)|psi-mi:Znf263(display_short)|uniprotkb:FPM315(gene name synonym)|uniprotkb:ZKSCAN12(gene name synonym)|uniprotkb:Zfp263(gene name synonym)|uniprotkb:Zinc finger protein FPM315(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675176|imex:IM-28774-2055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666314.1|reactome:R-MMU-212436|ensembl:ENSMUST00000060783(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSMUSG00000047371(gene)|entrezgene/locuslink:233890(identity) ensembl:ENSMUSG00000022529(gene)|ensembl:ENSMUST00000023176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030752|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_683726.2|entrezgene/locuslink:74120(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bTUdW3fkPL/cBbA+jzd78iNMw4c10090 rogid:psPERDxBYR4ymhFeKtm03GkxOzg10090 rigid:AqjYmNlAjXtemJvqcbxQnAfdcA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R0T2 uniprotkb:S4R1L6 intact:EBI-644020|ensembl:ENSMUSP00000055374 intact:EBI-26667038|ensembl:ENSMUSP00000138271 psi-mi:zn768_mouse(display_long)|uniprotkb:Znf768(gene name)|psi-mi:Znf768(display_short)|uniprotkb:Zfp768(gene name synonym) psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675168|imex:IM-28774-3295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666314.1|reactome:R-MMU-212436|ensembl:ENSMUST00000060783(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSMUSG00000047371(gene)|entrezgene/locuslink:233890(identity) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bTUdW3fkPL/cBbA+jzd78iNMw4c10090 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rigid:LHZWbpU6EALY0VxVDqsLgPdAEuM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K284 uniprotkb:O35137 intact:EBI-8412484|uniprotkb:Q8CAL9|intact:MINT-4137479|ensembl:ENSMUSP00000056719 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:tf3c1_mouse(display_long)|uniprotkb:Gtf3c1(gene name)|psi-mi:Gtf3c1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675160|imex:IM-28774-3293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_997122.1|ensembl:ENSMUSG00000032777(gene)|ensembl:ENSMUST00000055506(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007309(B-block binding subunit of TFIIIC)|interpro:IPR035625|interpro:IPR044210|mint:Q8K284|reactome:R-MMU-76061|reactome:R-MMU-76066|entrezgene/locuslink:233863(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - comment:mint|function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vL28aV6mHktcbaTvhC+U3jxtrAY10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:RlOSfd3d5HpygNBC73Z4jXLWEn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8BHZ4 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-6261115|ensembl:ENSMUSP00000102976|uniprotkb:Q80XM1 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:zn592_mouse(display_long)|uniprotkb:Kiaa0211(gene name synonym)|uniprotkb:Zfp592(gene name synonym)|uniprotkb:Znf592(gene name)|psi-mi:Znf592(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675152|imex:IM-28774-1571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000005621(gene)|ensembl:ENSMUST00000107353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q8BHZ4|refseq:NP_848822.2|entrezgene/locuslink:233410(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:eTnikXtxcsynfo8/ZrEWL3NKL8g10090 rigid:3FoALDS6zxhf+bgE4IHwObOpE8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BHZ4 uniprotkb:Q07279 intact:EBI-6261115|ensembl:ENSMUSP00000102976|uniprotkb:Q80XM1 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:zn592_mouse(display_long)|uniprotkb:Kiaa0211(gene name synonym)|uniprotkb:Zfp592(gene name synonym)|uniprotkb:Znf592(gene name)|psi-mi:Znf592(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675144|imex:IM-28774-2877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000005621(gene)|ensembl:ENSMUST00000107353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q8BHZ4|refseq:NP_848822.2|entrezgene/locuslink:233410(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eTnikXtxcsynfo8/ZrEWL3NKL8g10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:xNPZP4jwdd+vsWoIqvfGQQUvyCg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BHZ4 uniprotkb:F8VPR5 intact:EBI-6261115|ensembl:ENSMUSP00000102976|uniprotkb:Q80XM1 intact:EBI-10989694|ensembl:ENSMUSP00000023165 psi-mi:zn592_mouse(display_long)|uniprotkb:Kiaa0211(gene name synonym)|uniprotkb:Zfp592(gene name synonym)|uniprotkb:Znf592(gene name)|psi-mi:Znf592(display_short) psi-mi:f8vpr5_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675136|imex:IM-28774-2053 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000005621(gene)|ensembl:ENSMUST00000107353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q8BHZ4|refseq:NP_848822.2|entrezgene/locuslink:233410(identity) refseq:NP_001020603.1|ensembl:ENSMUSG00000022521(gene)|ensembl:ENSMUST00000023165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:12914(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eTnikXtxcsynfo8/ZrEWL3NKL8g10090 rogid:9K1igrA8QbILB/vG1/XLKh9kzJM10090 rigid:J9nGnDAxnveyaAI5kfHJzslwcMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQC1 uniprotkb:O15062 intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q6IE80|uniprotkb:Q96GQ6|ensembl:ENSP00000378451 intact:EBI-722671|ensembl:ENSP00000307604 psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:zbtb5_human(display_long)|uniprotkb:ZBTB5(gene name)|psi-mi:ZBTB5(display_short)|uniprotkb:KIAA0354(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675128|imex:IM-28774-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|mint:Q9NQC1|reactome:R-HSA-3214847|entrezgene/locuslink:23338(identity) refseq:NP_055687.1|refseq:XP_005251691.1|dip:DIP-41566N|ensembl:ENSG00000168795(gene)|ensembl:ENST00000307750(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O15062|entrezgene/locuslink:9925(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 rogid:snw/pD42fIJp5zlezPU76fP1jZc9606 rigid:gnvIaGsRoJihR0n2snxjcYje3O4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFI7 uniprotkb:G3X904 intact:EBI-2549877|ensembl:ENSMUSP00000031167 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675120|imex:IM-28774-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N|entrezgene/locuslink:231329(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:1D7UK/3p6KlgKlnUWHH6SW0A3Ps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFI7 uniprotkb:Q07279 intact:EBI-2549877|ensembl:ENSMUSP00000031167 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675112|imex:IM-28774-1139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N|entrezgene/locuslink:231329(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:WZQWJ0ir7pwfAwDOZrZ7tT2UhV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFI7 uniprotkb:Q61545 intact:EBI-2549877|ensembl:ENSMUSP00000031167 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rpb2_mouse(display_long)|uniprotkb:Polr2b(gene name)|psi-mi:Polr2b(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675104|imex:IM-28774-3291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029250(gene)|ensembl:ENSMUST00000031167(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q8CFI7|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_722493.2|dip:DIP-57023N|entrezgene/locuslink:231329(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Tmvj+m8fdVI+HHVma1Y0WYCSl4c10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:OIAjXsoxEK6uAhwusdQzcnrjYf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q921F2 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675096|imex:IM-28774-1137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1|entrezgene/locuslink:230908(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rigid:wIDUEoecwKpKvQTdtJQqu+dT1CM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921F2 uniprotkb:Q9D902 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675088|imex:IM-28774-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1|entrezgene/locuslink:230908(identity) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rigid:G5lo6bXVu6Xdhe7mcA6pjIspXf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921F2 uniprotkb:Q921F2 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675072|imex:IM-28774-2875 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1|entrezgene/locuslink:230908(identity) refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1|entrezgene/locuslink:230908(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rigid:dAUQIk7Aa0ggtzzac3loXeE4CZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921F2 uniprotkb:G3UW74 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 intact:EBI-5745202|ensembl:ENSMUSP00000129375 psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:g3uw74_mouse(display_long)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short)|uniprotkb:MED16(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675064|imex:IM-28774-2051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1|entrezgene/locuslink:230908(identity) refseq:NP_932775.2|ensembl:ENSMUSG00000013833(gene)|ensembl:ENSMUST00000165684(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0016592"(mediator complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|entrezgene/locuslink:216154(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rogid:JHlt3TzmVPsiPRMYEvLvHhnrfNY10090 rigid:HE/Ib4oB4PdvjSlaDV5EvLeIcQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921F2 uniprotkb:P70662 intact:EBI-6876933|ensembl:ENSMUSP00000081142|uniprotkb:Q3U591|uniprotkb:Q3V0E7 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:tadbp_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:Tdp43(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675056|imex:IM-28774-1569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000084125(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q921F2|rcsb pdb:3D2W|refseq:NP_663531.1|entrezgene/locuslink:230908(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j1U3NZd8O/lAclOPSRt10NY58e810090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:GpYy6kyifqMc/+tmlVpXQW6GoOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43638 uniprotkb:P35226 intact:EBI-741338|ensembl:ENSP00000365145|uniprotkb:Q96D28 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:foxs1_human(display_long)|uniprotkb:FKHL18(gene name synonym)|uniprotkb:Forkhead-related transcription factor 10(gene name synonym)|uniprotkb:Forkhead-like 18 protein(gene name synonym)|uniprotkb:FOXS1(gene name)|psi-mi:FOXS1(display_short)|uniprotkb:FREAC10(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675048|imex:IM-28774-2873 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000179772(gene)|ensembl:ENST00000375978(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|refseq:NP_004109.1|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050885"(neuromuscular process controlling balance)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|entrezgene/locuslink:2307(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|entrezgene/locuslink:648(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ggx9LJd03OKCMuPasVwrr0Zletc9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:kBUIRGcR6e3Ig3bzckmACL/KMBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2E4 uniprotkb:P61457 intact:EBI-21630426|uniprotkb:B4DPI5|uniprotkb:Q5SS78|ensembl:ENSP00000280886 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:dip2c_human(display_long)|uniprotkb:DIP2C(gene name)|psi-mi:DIP2C(display_short)|uniprotkb:KIAA0934(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675040|imex:IM-28774-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055789.1|ensembl:ENSG00000151240(gene)|ensembl:ENST00000280886(transcript)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR010506(DMAP1-binding)|interpro:IPR037337|interpro:IPR042099|entrezgene/locuslink:22982(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XmGCkORWQdHqhkL+tF8+nVPEgpA9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:7Q5VkVPTv6z+6IOuJmZTLopbkew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91W50 uniprotkb:Q07279 intact:EBI-8318466|intact:MINT-4121285|ensembl:ENSMUSP00000029446|ensembl:ENSMUSP00000143503 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:csde1_mouse(display_long)|uniprotkb:Csde1(gene name)|psi-mi:Csde1(display_short)|uniprotkb:D3Jfr1(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675032|imex:IM-28774-3289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659150.1|refseq:XP_017175039.1|ensembl:ENSMUSG00000068823(gene)|ensembl:ENSMUST00000029446(transcript)|ensembl:ENSMUST00000197827(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|interpro:IPR024642|mint:Q91W50|entrezgene/locuslink:229663(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - comment:mint|function:"RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BLYLjo9V0qtWfPeN4Ke6JFZxWAQ10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:OxRC5Ew01pLQmfP/YpsuKMfKnO8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15022 uniprotkb:Q01844 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675257|imex:IM-28774-2057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|entrezgene/locuslink:23512(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:UwoeuPtDrewddXdZT1BMxyhM8mc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:Q14134 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675401|imex:IM-28774-1579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rigid:M+BQJZ57PhiCxqWzLtC1xxnheIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:Q9UNN4 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675281|imex:IM-28774-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rigid:Cnv7VurQiiVRw/rPLCkU/xNPsGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P09874 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675385|imex:IM-28774-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N|entrezgene/locuslink:142(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rigid:Z3n9WtUvtxiV1Tyt3XCvfTQofo4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWW4 uniprotkb:O43679 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675377|imex:IM-28774-2471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|entrezgene/locuslink:9079(identity) - crc64:DBBB169D4EE10536 crc64:E86387BA027F383A figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:L6bX54KnnkVH6crqEK3LaMbatMk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWW4 uniprotkb:Q9NYT6 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-20834409|ensembl:ENSP00000336719|ensembl:ENSP00000393265|ensembl:ENSP00000465121|uniprotkb:Q8WWE6|uniprotkb:Q96TE6|uniprotkb:Q9NS44 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:zn226_human(display_long)|uniprotkb:ZNF226(gene name)|psi-mi:ZNF226(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675369|imex:IM-28774-1577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) ensembl:ENSG00000167380(gene)|ensembl:ENST00000337433(transcript)|ensembl:ENST00000454662(transcript)|ensembl:ENST00000590089(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001027544.1|refseq:NP_001027545.1|refseq:NP_001027546.1|refseq:NP_001139692.1|refseq:NP_001306017.1|refseq:NP_001306018.1|refseq:NP_001306019.1|refseq:NP_057003.2|refseq:NP_057528.2|refseq:XP_005259284.1|refseq:XP_006723430.1|refseq:XP_006723431.1|refseq:XP_006723432.1|refseq:XP_016882751.1|refseq:XP_016882754.1|entrezgene/locuslink:7769(identity) - crc64:DBBB169D4EE10536 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:PUSlyfOnd/7j0DGp8yS+nRNrQVY9606 rigid:HL9SuMfbknlPWqlg+kQESU0Vkrk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWW4 uniprotkb:O00267 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675361|imex:IM-28774-1575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) - crc64:DBBB169D4EE10536 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:n1GZeu5ZfiU1XeoNMqjvIx6T4VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35251 uniprotkb:Q9BWW4 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675353|imex:IM-28774-1143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|entrezgene/locuslink:5981(identity) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) - - crc64:DBBB169D4EE10536 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rigid:DfHaPPuDgbsHLvDtPfNZ2fQn5jg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWW4 uniprotkb:O60663 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-296386|uniprotkb:O75463|uniprotkb:Q5JU95|uniprotkb:Q6ISC9|ensembl:ENSP00000362573|uniprotkb:F8W7W6 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:lmx1b_human(display_long)|uniprotkb:LMX1B(gene name)|psi-mi:LMX1B(display_short)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675345|imex:IM-28774-2469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000136944(gene)|ensembl:ENST00000373474(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001701"(in utero embryonic development)|refseq:NP_001167618.1|refseq:NP_002307.2|entrezgene/locuslink:4010(identity) - crc64:DBBB169D4EE10536 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:ERk5ljL48TxeUJQiYNxmIRYKNI89606 rigid:wAaiMXI0WUyWeb0dKO9sQHlyRII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWW4 uniprotkb:P14317 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675337|imex:IM-28774-2063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity) - crc64:DBBB169D4EE10536 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606 rigid:Tx7PPcplA4Gghl8oiVMLk0OMm4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:O43513 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675329|imex:IM-28774-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:UZRw56yFizzjl3a9ToKqe3W923M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:P05423 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675321|imex:IM-28774-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:14c61kA0W5Ykeo84FMVx4LLy7AQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:Q99729 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675313|imex:IM-28774-3305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N|entrezgene/locuslink:3182(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:IYZCFYBQe/UbYmAjF7dRb7/XIgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:O43251 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675297|imex:IM-28774-2061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:316SO7tE6FAOcQcdoAfA3eRTAVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:Q12926 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-11285353|uniprotkb:D3DRK3|uniprotkb:Q13235|uniprotkb:Q59G15|uniprotkb:Q8NEM4|uniprotkb:Q9H1Q8|ensembl:ENSP00000369460|ensembl:ENSP00000380479|ensembl:ENSP00000440998 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:elav2_human(display_long)|uniprotkb:ELAVL2(gene name)|psi-mi:ELAVL2(display_short)|uniprotkb:ELAV-like neuronal protein 1(gene name synonym)|uniprotkb:HUB(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)|uniprotkb:Nervous system-specific RNA-binding protein Hel-N1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675289|imex:IM-28774-2059 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) refseq:NP_001164666.1|refseq:NP_001164668.1|refseq:NP_004423.2|ensembl:ENSG00000107105(gene)|ensembl:ENST00000380117(transcript)|ensembl:ENST00000397312(transcript)|ensembl:ENST00000544538(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034914|interpro:IPR034999|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016869908.1|refseq:XP_016869909.1|refseq:XP_016869910.1|refseq:XP_016869911.1|refseq:XP_016869912.1|refseq:XP_016869913.1|refseq:XP_016869914.1|entrezgene/locuslink:1993(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:Z17PDyoxDFJbfrFlvD3xS91rtLk9606 rigid:cJ8cDRwue1mEJBOqcrCRz8fvzps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43251 uniprotkb:Q13111 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675273|imex:IM-28774-1141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|entrezgene/locuslink:10036(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:x14S0MZUYuLaM05ZhyNREeVumtI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5R6 uniprotkb:Q14134 intact:EBI-7963304|intact:MINT-7969865|uniprotkb:Q8IW77|uniprotkb:Q6T1H9|uniprotkb:B2R913|uniprotkb:Q6T1H8|ensembl:ENSP00000371711 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 psi-mi:dmrt1_human(display_long)|uniprotkb:DMRT1(gene name)|psi-mi:DMRT1(display_short)|uniprotkb:DMT1(gene name synonym)|uniprotkb:DM domain expressed in testis protein 1(gene name synonym) psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675393|imex:IM-28774-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068770.2|dip:DIP-58084N|ensembl:ENSG00000137090(gene)|ensembl:ENST00000382276(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0008354"(germ cell migration)|go:"GO:0030238"(male sex determination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046661"(male sex differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060903"(positive regulation of meiosis I)|go:"GO:1900107"(regulation of nodal signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR001275(DM DNA-binding)|interpro:IPR022114|interpro:IPR026607|interpro:IPR036407|rcsb pdb:4YJ0|reactome:R-HSA-9690406|entrezgene/locuslink:1761(identity) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) - comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Cs7F3GtR7WrzG+e8NndwTXlW4hg9606 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rigid:fmB4XYjoI4/1XTO2A759Ioo+4ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULX9 uniprotkb:P37231 intact:EBI-721128|uniprotkb:B4DV49|uniprotkb:Q9Y525|ensembl:ENSP00000345393|ensembl:ENSP00000384094|ensembl:ENSP00000388882|ensembl:ENSP00000442060 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:maff_human(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog F(gene name synonym)|uniprotkb:MAFF(gene name)|psi-mi:MAFF(display_short)|uniprotkb:U-Maf(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675553|imex:IM-28774-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155044.1|refseq:NP_001155045.1|refseq:NP_001155046.1|refseq:NP_036455.1|ensembl:ENSG00000185022(gene)|ensembl:ENST00000338483(transcript)|ensembl:ENST00000407965(transcript)|ensembl:ENST00000426621(transcript)|ensembl:ENST00000538320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007567"(parturition)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR033531|mint:Q9ULX9|reactome:R-HSA-983231|entrezgene/locuslink:23764(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gMt7XusD+WbsF+JZ4vxJgdGJXO89606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:hJC9JW74DmCj27fq1hoQ/UovLto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q9ULX9 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-721128|uniprotkb:B4DV49|uniprotkb:Q9Y525|ensembl:ENSP00000345393|ensembl:ENSP00000384094|ensembl:ENSP00000388882|ensembl:ENSP00000442060 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:maff_human(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog F(gene name synonym)|uniprotkb:MAFF(gene name)|psi-mi:MAFF(display_short)|uniprotkb:U-Maf(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675545|imex:IM-28774-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_001155044.1|refseq:NP_001155045.1|refseq:NP_001155046.1|refseq:NP_036455.1|ensembl:ENSG00000185022(gene)|ensembl:ENST00000338483(transcript)|ensembl:ENST00000407965(transcript)|ensembl:ENST00000426621(transcript)|ensembl:ENST00000538320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007567"(parturition)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR033531|mint:Q9ULX9|reactome:R-HSA-983231|entrezgene/locuslink:23764(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:gMt7XusD+WbsF+JZ4vxJgdGJXO89606 rigid:dDLx44gSl/M9hRQpTJ0401ClFGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULX9 uniprotkb:Q9UNN4 intact:EBI-721128|uniprotkb:B4DV49|uniprotkb:Q9Y525|ensembl:ENSP00000345393|ensembl:ENSP00000384094|ensembl:ENSP00000388882|ensembl:ENSP00000442060 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 psi-mi:maff_human(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog F(gene name synonym)|uniprotkb:MAFF(gene name)|psi-mi:MAFF(display_short)|uniprotkb:U-Maf(gene name synonym) psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675537|imex:IM-28774-3315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155044.1|refseq:NP_001155045.1|refseq:NP_001155046.1|refseq:NP_036455.1|ensembl:ENSG00000185022(gene)|ensembl:ENST00000338483(transcript)|ensembl:ENST00000407965(transcript)|ensembl:ENST00000426621(transcript)|ensembl:ENST00000538320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007567"(parturition)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR033531|mint:Q9ULX9|reactome:R-HSA-983231|entrezgene/locuslink:23764(identity) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gMt7XusD+WbsF+JZ4vxJgdGJXO89606 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rigid:nOHvBalud/oml4x4pZFwG5s+PYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULX9 uniprotkb:Q9UQL6 intact:EBI-721128|uniprotkb:B4DV49|uniprotkb:Q9Y525|ensembl:ENSP00000345393|ensembl:ENSP00000384094|ensembl:ENSP00000388882|ensembl:ENSP00000442060 intact:EBI-715576|uniprotkb:O60340|uniprotkb:O60528|uniprotkb:Q96DY4|intact:EBI-28970762|uniprotkb:C9JFV9|ensembl:ENSP00000468004|ensembl:ENSP00000507606 psi-mi:maff_human(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog F(gene name synonym)|uniprotkb:MAFF(gene name)|psi-mi:MAFF(display_short)|uniprotkb:U-Maf(gene name synonym) psi-mi:hdac5_human(display_long)|uniprotkb:Antigen NY-CO-9(gene name synonym)|uniprotkb:HDAC5(gene name)|psi-mi:HDAC5(display_short)|uniprotkb:KIAA0600(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675529|imex:IM-28774-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155044.1|refseq:NP_001155045.1|refseq:NP_001155046.1|refseq:NP_036455.1|ensembl:ENSG00000185022(gene)|ensembl:ENST00000338483(transcript)|ensembl:ENST00000407965(transcript)|ensembl:ENST00000426621(transcript)|ensembl:ENST00000538320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007567"(parturition)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR033531|mint:Q9ULX9|reactome:R-HSA-983231|entrezgene/locuslink:23764(identity) refseq:NP_001015053.1|refseq:NP_005465.2|refseq:XP_005256963.1|ensembl:ENST00000225983|ensembl:ENSP00000225983|ensembl:ENST00000336057|ensembl:ENSP00000337290|ensembl:ENSP00000468004|ensembl:ENSP00000507606|dip:DIP-38260N|rcsb pdb:5UWI|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8943724|mint:Q9UQL6|ensembl:ENSG00000108840(gene)|ensembl:ENST00000586802(transcript)|ensembl:ENST00000682912(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010830"(regulation of myotube differentiation)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR030703|interpro:IPR037138|entrezgene/locuslink:10014(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gMt7XusD+WbsF+JZ4vxJgdGJXO89606 rogid:fI8A5VuOawGthBb/65R47AEGZ/Y9606 rigid:yTSry7Qs+tvvhVKgjbw28lpOlSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62340 uniprotkb:Q8R4I4 intact:EBI-7640256|ensembl:ENSMUSP00000093470|ensembl:ENSMUSP00000114223|uniprotkb:O95753|intact:MINT-1348231|uniprotkb:Q9Z2Z0 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 psi-mi:tbpl1_mouse(display_long)|uniprotkb:Tbpl1(gene name)|psi-mi:Tbpl1(display_short)|uniprotkb:Tlp(gene name synonym)|uniprotkb:Tlp21(gene name synonym)|uniprotkb:Tlf(gene name synonym)|uniprotkb:Trf2(gene name synonym)|uniprotkb:Trp(gene name synonym)|uniprotkb:TATA box-binding protein-related factor 2(gene name synonym)|uniprotkb:TBP-like factor(gene name synonym)|uniprotkb:TBP-related protein(gene name synonym)|uniprotkb:21 kDa TBP-like protein(gene name synonym) psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675521|imex:IM-28774-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071359(gene)|ensembl:ENSMUST00000095794(transcript)|ensembl:ENSMUST00000127698(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR015445(TATA-Box binding protein-like)|refseq:NP_035733.1|refseq:XP_006512793.1|entrezgene/locuslink:237336(identity) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) - function:Does not bind the TATA box. Has DNA-binding ability|comment:mint comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xMdqGuzUlbzGS1MsLP100y1CiVc10090 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rigid:ndku3JiZaQFmG7SWM3h8mibwESw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:O43513 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675513|imex:IM-28774-2477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:moiPSjCO+CQc7i+RerydLxs4Qfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:Q9Y6K9 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675505|imex:IM-28774-2475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:5IQu4ZG7uNs56YMF0NvGi7OXels false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:Q9Y6K9 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675497|imex:IM-28774-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:5IQu4ZG7uNs56YMF0NvGi7OXels false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P23497 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675489|imex:IM-28774-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE|entrezgene/locuslink:6672(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rigid:OoJxkugAZb0bOlqJQu88BZgBdZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:Q16533 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-11915024|ensembl:ENSP00000216294 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:snpc1_human(display_long)|uniprotkb:SNAPC1(gene name)|psi-mi:SNAPC1(display_short)|uniprotkb:Proximal sequence element-binding transcription factor subunit gamma(gene name synonym)|uniprotkb:SNAP43(gene name synonym)|uniprotkb:Small nuclear RNA-activating complex polypeptide 1(gene name synonym)|uniprotkb:snRNA-activating protein complex 43 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675481|imex:IM-28774-2885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) ensembl:ENSG00000023608(gene)|ensembl:ENST00000216294(transcript)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR019188|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|refseq:NP_003073.1|dip:DIP-504N|entrezgene/locuslink:6617(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:xXCySYpmgoo2VmzFtT1iRFFUkj49606 rigid:+9EbYp6LcLchI5Qqm8iLmlPELdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:O60902 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-5278206|uniprotkb:O60465|uniprotkb:O60467|uniprotkb:O60903|ensembl:ENSP00000397099 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:shox2_human(display_long)|uniprotkb:SHOX2(gene name)|psi-mi:SHOX2(display_short)|uniprotkb:OG12X(gene name synonym)|uniprotkb:SHOT(gene name synonym)|uniprotkb:Homeobox protein Og12X(gene name synonym)|uniprotkb:Paired-related homeobox protein SHOT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675473|imex:IM-28774-2883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_001157150.1|refseq:NP_003021.3|refseq:NP_006875.2|refseq:XP_006713791.1|refseq:XP_016862544.1|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060920"(cardiac pacemaker cell differentiation)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENST00000441443(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0003163"(sinoatrial node development)|go:"GO:0003172"(sinoatrial valve development)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|ensembl:ENSG00000168779(gene)|entrezgene/locuslink:6474(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:KGs4JbbEL/J1oITNTQC3K5OF1P89606 rigid:vrNysInACRUCAyQUXY3gV7VDAxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P14373 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675465|imex:IM-28774-3313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rigid:6CToMxdyVv5se61duABvbZyNuKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P19388 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675457|imex:IM-28774-2067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N|entrezgene/locuslink:5434(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:MZf28uL2NFvrYJ8dmwTE+ZNT11I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:O15514 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675449|imex:IM-28774-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N|entrezgene/locuslink:5433(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:oI/LZ7L4aBXUF0wRpYVd/39HiQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:O43900 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-1751761|uniprotkb:O76007|uniprotkb:Q53XR5|uniprotkb:B7Z8F2|intact:EBI-11047712|ensembl:ENSP00000470248 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:pric3_human(display_long)|uniprotkb:Prickle-like protein 3(gene name synonym)|uniprotkb:PRICKLE3(gene name)|psi-mi:PRICKLE3(display_short)|uniprotkb:LMO6(gene name synonym)|uniprotkb:LIM domain only protein 6(gene name synonym)|uniprotkb:Triple LIM domain protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675441|imex:IM-28774-3311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_006141.2|ensembl:ENSG00000012211(gene)|ensembl:ENST00000599218(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030030"(cell projection organization)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033725|interpro:IPR033726|interpro:IPR033727|entrezgene/locuslink:4007(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:Vt4H/FRDJL0+3jmrQtCFiA+TwiA9606 rigid:84k33s7pmt3vBKhcUFtrW6M8TwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P14317 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675433|imex:IM-28774-3309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606 rigid:1ntFnfqH0ZFhFK+1D4Nm0aQM1WM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P29083 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675425|imex:IM-28774-2065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:xtGgWHlGjugArS0EaDtq44F9yLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14134 uniprotkb:P15976 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675417|imex:IM-28774-3307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:rTEqvAHTF2wBv6n68RpjMXrK9rU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:Q9WVB3 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675785|imex:IM-28774-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:57DOkQaM+STUCFpoTeG65aIjeK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:S4R1L6 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-26667038|ensembl:ENSMUSP00000138271 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:s4r1l6_mouse(display_long)|uniprotkb:Mzf1(gene name)|psi-mi:Mzf1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675777|imex:IM-28774-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) ensembl:ENSMUSG00000030380(gene)|ensembl:ENSMUST00000182490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_006539528.1|entrezgene/locuslink:109889(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:T26RRAnSSf20pyjoEU7sOPEdYDY10090 rigid:22s3H2DjrML3Xdo7H5SRfVyyL9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:Q6PD29 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-3044009|ensembl:ENSMUSP00000110238|uniprotkb:Q3U4K1|uniprotkb:Q8BWH6 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:zn513_mouse(display_long)|uniprotkb:Znf513(gene name)|psi-mi:Znf513(display_short)|uniprotkb:Zfp513(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675769|imex:IM-28774-3319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) ensembl:ENSMUSG00000043059(gene)|ensembl:ENSMUST00000114590(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001171372.1|refseq:NP_780520.3|refseq:XP_006503720.2|entrezgene/locuslink:101023(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:Uv2jsMClXB89tOJP1vn8uzWMQUw10090 rigid:JQznSMHQhMtRlmE/e/wYjDbP+8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P56931 uniprotkb:A0A087WPU8 intact:EBI-8407856|uniprotkb:Q8BID0|intact:MINT-4110723|uniprotkb:A2AW43|ensembl:ENSMUSP00000050047 intact:EBI-26673036|ensembl:ENSMUSP00000139926 psi-mi:e2f2_mouse(display_long)|uniprotkb:E2f2(gene name)|psi-mi:E2f2(display_short) psi-mi:a0a087wpu8_mouse(display_long)|uniprotkb:Tfdp2(gene name)|psi-mi:Tfdp2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675723|imex:IM-28774-1149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001292328.1|refseq:NP_808401.1|dip:DIP-48416N|ensembl:ENSMUSG00000018983(gene)|ensembl:ENSMUST00000061721(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:P56931|reactome:R-MMU-68689|reactome:R-MMU-69231|entrezgene/locuslink:242705(identity) ensembl:ENSMUSG00000032411(gene)|ensembl:ENSMUST00000188750(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|refseq:XP_006511025.1|entrezgene/locuslink:211586(identity) - comment:mint|function:Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ebVOQy8CKAIioLYr2e9X9yaiZW810090 rogid:oe+23BW7WmwtrF524SSLaWSgKNI10090 rigid:UvkF6hnbWR9IB9teIVZ8MKRP0Bc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTP9 uniprotkb:Q9QZ28 intact:EBI-26674907|ensembl:ENSMUSP00000035976 intact:EBI-348987|uniprotkb:O88423|ensembl:ENSMUSP00000021519 psi-mi:vax2_mouse(display_long)|uniprotkb:Ventral retina homeodomain protein(gene name synonym)|uniprotkb:Vax2(gene name)|psi-mi:Vax2(display_short)|uniprotkb:Vex(gene name synonym) psi-mi:six6_mouse(display_long)|uniprotkb:Six6(gene name)|psi-mi:Six6(display_short)|uniprotkb:Optx2(gene name synonym)|uniprotkb:Six9(gene name synonym)|uniprotkb:Sine oculis homeobox homolog 6(gene name synonym)|uniprotkb:Optic homeobox 2(gene name synonym)|uniprotkb:Six9 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675715|imex:IM-28774-1583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034777(gene)|ensembl:ENSMUST00000037807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033021|go:"GO:0043010"(camera-type eye development)|refseq:NP_036042.1|entrezgene/locuslink:24113(identity) refseq:NP_035514.1|ensembl:ENSMUSG00000021099(gene)|ensembl:ENSMUST00000021519(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR031701|interpro:IPR032947|entrezgene/locuslink:20476(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gyaEel7JgrCB8jlzkvFdzD+fZBU10090 rogid:LE6vGckqrqLOASpqOf6dhsyntYI10090 rigid:1A8mGTCvf8pl+AwIOt6A5O0zLPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTP9 uniprotkb:Q9Z205 intact:EBI-26674907|ensembl:ENSMUSP00000035976 intact:EBI-26672134|ensembl:ENSMUSP00000148739 psi-mi:vax2_mouse(display_long)|uniprotkb:Ventral retina homeodomain protein(gene name synonym)|uniprotkb:Vax2(gene name)|psi-mi:Vax2(display_short)|uniprotkb:Vex(gene name synonym) psi-mi:rfxk_mouse(display_long)|uniprotkb:Ankyrin repeat-containing adapter protein Tvl-1(gene name synonym)|uniprotkb:Regulatory factor X subunit B(gene name synonym)|uniprotkb:Regulatory factor X-associated ankyrin-containing protein(gene name synonym)|uniprotkb:Rfxank(gene name)|psi-mi:Rfxank(display_short)|uniprotkb:Rfxb(gene name synonym)|uniprotkb:Tvl1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675707|imex:IM-28774-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034777(gene)|ensembl:ENSMUST00000037807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033021|go:"GO:0043010"(camera-type eye development)|refseq:NP_036042.1|entrezgene/locuslink:24113(identity) ensembl:ENSMUSG00000036120(gene)|ensembl:ENSMUST00000212320(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017362(DNA-binding, RFXANK)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001020760.1|refseq:NP_035396.1|entrezgene/locuslink:19727(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gyaEel7JgrCB8jlzkvFdzD+fZBU10090 rogid:KIPun2JlrxVeu5/237St+5P017410090 rigid:fy1d9nHPodjyGQK9a8aUdV4/GH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63015 uniprotkb:Q9WTP9 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 intact:EBI-26674907|ensembl:ENSMUSP00000035976 psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:vax2_mouse(display_long)|uniprotkb:Ventral retina homeodomain protein(gene name synonym)|uniprotkb:Vax2(gene name)|psi-mi:Vax2(display_short)|uniprotkb:Vex(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675699|imex:IM-28774-1581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like)|entrezgene/locuslink:18508(identity) ensembl:ENSMUSG00000034777(gene)|ensembl:ENSMUST00000037807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033021|go:"GO:0043010"(camera-type eye development)|refseq:NP_036042.1|entrezgene/locuslink:24113(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 rogid:gyaEel7JgrCB8jlzkvFdzD+fZBU10090 rigid:6VouFpwXfpA7MHChzcy6ryRc2vo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VHI4 uniprotkb:Q07279 intact:EBI-26675664|ensembl:ENSMUSP00000137825|ensembl:ENSMUSP00000141169|uniprotkb:B2RRZ9 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:cartf_mouse(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein(gene name synonym)|uniprotkb:Calcium-response factor(gene name synonym)|uniprotkb:Carf(gene name)|psi-mi:Carf(display_short)|uniprotkb:Als2cr8(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675691|imex:IM-28774-2481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026017(gene)|ensembl:ENSMUST00000180952(transcript)|ensembl:ENSMUST00000187978(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0061400"(positive regulation of transcription from RNA polymerase II promoter in response to calcium ion)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR029309|refseq:NP_001272402.1|refseq:NP_631889.1|refseq:XP_011236812.1|refseq:XP_017176083.1|entrezgene/locuslink:241066(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PaBWEbbjk6OSJqPuCYc28adiOac10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:FO4FfjHBFAspuzRoLXRyxYpCGyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZ34 uniprotkb:Q9D0B1 intact:EBI-26675593|ensembl:ENSMUSP00000133212|uniprotkb:Q14DN8 intact:EBI-26675631|ensembl:ENSMUSP00000083533|ensembl:ENSMUSP00000146921|ensembl:ENSMUSP00000147095|uniprotkb:Q9DCQ0 psi-mi:zn641_mouse(display_long)|uniprotkb:Znf641(gene name)|psi-mi:Znf641(display_short)|uniprotkb:Zfp641(gene name synonym) psi-mi:zn524_mouse(display_long)|uniprotkb:Znf524(gene name)|psi-mi:Znf524(display_short)|uniprotkb:Zfp524(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675656|imex:IM-28774-1147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022987(gene)|ensembl:ENSMUST00000169721(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_776130.1|refseq:XP_006521032.1|refseq:XP_006521033.1|refseq:XP_006521034.1|refseq:XP_006521035.1|refseq:XP_011243929.1|refseq:XP_017172093.1|entrezgene/locuslink:239652(identity) ensembl:ENSMUSG00000051184(gene)|ensembl:ENSMUST00000086349(transcript)|ensembl:ENSMUST00000207901(transcript)|ensembl:ENSMUST00000209030(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_079600.1|refseq:XP_006540339.1|refseq:XP_006540340.1|refseq:XP_011248972.1|entrezgene/locuslink:66056(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iP2GGJ9yceeJGxdkmqzRQvvt87A10090 rogid:3r5PrVMS0Wc3Mdx9dcG41RrT0K410090 rigid:AByPZ4/HOnyJYVvb/T138KjC0uU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BZ34 uniprotkb:Q9ER42 intact:EBI-26675593|ensembl:ENSMUSP00000133212|uniprotkb:Q14DN8 intact:EBI-26668483|ensembl:ENSMUSP00000021813|uniprotkb:O09066|uniprotkb:P70159|uniprotkb:Q0VF04|uniprotkb:Q9ERV2 psi-mi:zn641_mouse(display_long)|uniprotkb:Znf641(gene name)|psi-mi:Znf641(display_short)|uniprotkb:Zfp641(gene name synonym) psi-mi:barx1_mouse(display_long)|uniprotkb:Barx1(gene name)|psi-mi:Barx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675623|imex:IM-28774-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022987(gene)|ensembl:ENSMUST00000169721(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_776130.1|refseq:XP_006521032.1|refseq:XP_006521033.1|refseq:XP_006521034.1|refseq:XP_006521035.1|refseq:XP_011243929.1|refseq:XP_017172093.1|entrezgene/locuslink:239652(identity) ensembl:ENSMUSG00000021381(gene)|ensembl:ENSMUST00000021813(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009888"(tissue development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0055123"(digestive system development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048513"(animal organ development)|go:"GO:0048536"(spleen development)|refseq:NP_031552.2|entrezgene/locuslink:12022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iP2GGJ9yceeJGxdkmqzRQvvt87A10090 rogid:V+GjyYmD/YOniBu1zoeQp/wF7dw10090 rigid:yDxmcVVc66HGkaxJkteF0W19h58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JIB4 uniprotkb:Q07279 intact:EBI-6260800|ensembl:ENSMUSP00000065228 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:tf2h2_mouse(display_long)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:Btf2p44(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Gtf2h2(gene name)|psi-mi:Gtf2h2(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675585|imex:IM-28774-1145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000066984(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|ensembl:ENSMUSG00000021639(gene)|refseq:NP_071294.3|entrezgene/locuslink:23894(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:B1sNNBPY99dly+ZymdKJeaj6nWA10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:NB3FFK53wOzUCVh7viATksQD904 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JIB4 uniprotkb:Q60925 intact:EBI-6260800|ensembl:ENSMUSP00000065228 intact:EBI-26673677|ensembl:ENSMUSP00000079693|uniprotkb:Q8VCX3 psi-mi:tf2h2_mouse(display_long)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:Btf2p44(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Gtf2h2(gene name)|psi-mi:Gtf2h2(display_short) psi-mi:dbp_mouse(display_long)|uniprotkb:Albumin D box-binding protein(gene name synonym)|uniprotkb:Albumin D-element-binding protein(gene name synonym)|uniprotkb:Dbp(gene name)|psi-mi:Dbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675577|imex:IM-28774-2479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000066984(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|ensembl:ENSMUSG00000021639(gene)|refseq:NP_071294.3|entrezgene/locuslink:23894(identity) ensembl:ENSMUSG00000059824(gene)|ensembl:ENSMUST00000080885(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029830|interpro:IPR040223|refseq:NP_058670.2|entrezgene/locuslink:13170(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:B1sNNBPY99dly+ZymdKJeaj6nWA10090 rogid:lcwsGCIxlexVpSuZTjEuZDgymlA10090 rigid:MmeYmumSieeKI+omukY3A9636eQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91X20 uniprotkb:Q07279 intact:EBI-1556554|uniprotkb:Q3UIF9|uniprotkb:Q9Z2X4|ensembl:ENSMUSP00000070957 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:ash2l_mouse(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:Ash2l(gene name)|psi-mi:Ash2l(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675569|imex:IM-28774-2069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035921.2|dip:DIP-39161N|ensembl:ENSMUSG00000031575(gene)|ensembl:ENSMUST00000068892(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048096"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q91X20|reactome:R-MMU-201722|reactome:R-MMU-3214841|reactome:R-MMU-8936459|entrezgene/locuslink:23808(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3ub+DLUG8tmHIoZHh9j8/bHHMWY10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:kzJAlQBqy9F1qMDhMnbDijrpUpw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SXJ3 uniprotkb:O55144 intact:EBI-22014755|uniprotkb:Q8BJQ8|uniprotkb:Q8BKI6|ensembl:ENSMUSP00000043108 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:fancj_mouse(display_long)|uniprotkb:Brip1(gene name)|psi-mi:Brip1(display_short)|uniprotkb:Bach1(gene name synonym)|uniprotkb:Fancj(gene name synonym)|uniprotkb:ATP-dependent RNA helicase BRIP1(gene name synonym)|uniprotkb:BRCA1-associated C-terminal helicase 1(gene name synonym)|uniprotkb:BRCA1-interacting protein C-terminal helicase 1(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675561|imex:IM-28774-3317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_840094.1|refseq:XP_006533302.1|ensembl:ENSMUSG00000034329(gene)|ensembl:ENSMUST00000044423(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010705"(meiotic DNA double-strand break processing involved in reciprocal meiotic recombination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071295"(cellular response to vitamin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693568|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|entrezgene/locuslink:237911(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PHHPxxaaDj7835pRdOGZYpKlC6A10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:Nqe8LT1WFKvRSQ2kUuaUUZcQAV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:Q9UDV6 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676150|imex:IM-28774-2075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rigid:m7IOZpNZecpahrV2ZtXjsREcpD4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:Q7TSI0 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-26675827|ensembl:ENSMUSP00000032591|uniprotkb:Q8C7Q7 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:znf12_mouse(display_long)|uniprotkb:Znf12(gene name)|psi-mi:Znf12(display_short)|uniprotkb:Zfp12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675857|imex:IM-28774-2887 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) ensembl:ENSMUSG00000029587(gene)|ensembl:ENSMUST00000032591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_001276518.1|refseq:NP_001276519.1|refseq:NP_808349.1|refseq:XP_017176364.1|entrezgene/locuslink:231866(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:iUY0Es8n3ad3fzwvfJVwniigbZ810090 rigid:OvpKdPMIojD+6+8/SwFvVlsUCLY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:Q8R0T2 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-644020|ensembl:ENSMUSP00000055374 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:zn768_mouse(display_long)|uniprotkb:Znf768(gene name)|psi-mi:Znf768(display_short)|uniprotkb:Zfp768(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675865|imex:IM-28774-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) refseq:NP_666314.1|reactome:R-MMU-212436|ensembl:ENSMUST00000060783(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSMUSG00000047371(gene)|entrezgene/locuslink:233890(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:bTUdW3fkPL/cBbA+jzd78iNMw4c10090 rigid:O5/hCOK+ZOFZg4rkcsga7e1rAKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:Q9CZK6 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-26675873|ensembl:ENSMUSP00000023157|uniprotkb:Q6ZPF6|uniprotkb:Q80X46 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:anks3_mouse(display_long)|uniprotkb:Anks3(gene name)|psi-mi:Anks3(display_short)|uniprotkb:Kiaa1977(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675891|imex:IM-28774-2483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) ensembl:ENSMUSG00000022515(gene)|ensembl:ENSMUST00000023157(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|refseq:NP_082577.2|entrezgene/locuslink:72615(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:LRIwqpLLTOJZzsXDuttcg12w99k10090 rigid:1Kgm6bEXwe3hYQEKd9ndtujX0aM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CWU2 uniprotkb:P61458 intact:EBI-8430035|intact:MINT-4140521|uniprotkb:Q3UKV1|uniprotkb:Q3UK32|ensembl:ENSMUSP00000112498 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:zdh13_mouse(display_long)|uniprotkb:Zdhhc13(gene name)|psi-mi:Zdhhc13(display_short)|uniprotkb:Hip14l(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 13(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14-related protein(gene name synonym) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675899|imex:IM-28774-3321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082307.1|ensembl:ENSMUSG00000030471(gene)|ensembl:ENSMUST00000118927(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030290|interpro:IPR036770|mint:Q9CWU2|entrezgene/locuslink:243983(identity) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) - function:May be involved in the NF-kappa-B signaling pathway|comment:mint function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JOcxB1KD8I67o1rhpbrbENZDWrA10090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rigid:JOigzkz+0kNXIPnMdIVIWK1n1Hw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CWU2 uniprotkb:Q04207 intact:EBI-8430035|intact:MINT-4140521|uniprotkb:Q3UKV1|uniprotkb:Q3UK32|ensembl:ENSMUSP00000112498 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:zdh13_mouse(display_long)|uniprotkb:Zdhhc13(gene name)|psi-mi:Zdhhc13(display_short)|uniprotkb:Hip14l(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 13(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14-related protein(gene name synonym) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675907|imex:IM-28774-1151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082307.1|ensembl:ENSMUSG00000030471(gene)|ensembl:ENSMUST00000118927(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030290|interpro:IPR036770|mint:Q9CWU2|entrezgene/locuslink:243983(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - function:May be involved in the NF-kappa-B signaling pathway|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JOcxB1KD8I67o1rhpbrbENZDWrA10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:7nor+PYx0fFDH5ZfB5hd3x7ITSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80W03 uniprotkb:Q8BGJ0 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 intact:EBI-26666876|ensembl:ENSMUSP00000047615|uniprotkb:Q3TV63|uniprotkb:Q8BMB7 psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:zdh15_mouse(display_long)|uniprotkb:Acyltransferase ZDHHC15(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 15(gene name synonym)|uniprotkb:Zdhhc15(gene name)|psi-mi:Zdhhc15(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675942|imex:IM-28774-3323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) ensembl:ENSMUSG00000033906(gene)|ensembl:ENSMUST00000042070(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0062237"(protein localization to postsynapse)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|go:"GO:0140450"(protein targeting to Golgi apparatus)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001594(Zinc finger, DHHC-type)|refseq:NP_780567.1|entrezgene/locuslink:108672(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rogid:jH+pF/BqSaECH0tZWEW3DusdBZE10090 rigid:GHAFjM9DmKuI+HMe/m97cAVxklQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80W03 uniprotkb:P13864 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 intact:EBI-301927|uniprotkb:Q80ZU3|uniprotkb:Q9CSC6|uniprotkb:P97413|uniprotkb:Q9QXX6|ensembl:ENSMUSP00000004202 psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:dnmt1_mouse(display_long)|uniprotkb:Dnmt1(gene name)|psi-mi:Dnmt1(display_short)|uniprotkb:Dnmt(gene name synonym)|uniprotkb:Met1(gene name synonym)|uniprotkb:Uim(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase MmuI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675950|imex:IM-28774-2889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) refseq:NP_001186360.2|refseq:NP_001186361.1|refseq:NP_001186362.1|refseq:NP_034196.5|interpro:IPR031303|interpro:IPR043151|mint:P13864|rcsb pdb:3AV4|rcsb pdb:3AV5|rcsb pdb:3AV6|rcsb pdb:3PT6|rcsb pdb:3PT9|rcsb pdb:4DA4|rcsb pdb:5GUT|rcsb pdb:5GUV|rcsb pdb:5WY1|rcsb pdb:6W8V|rcsb pdb:6W8W|reactome:R-MMU-212300|reactome:R-MMU-4655427|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|ensembl:ENSMUST00000004202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0044026"(DNA hypermethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051718"("DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates")|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:0016458"(obsolete gene silencing)|ensembl:ENSMUSG00000004099(gene)|refseq:NP_001300940.1|entrezgene/locuslink:13433(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rogid:JgHTnDhDn4nuU6ww3jXfDPq01xY10090 rigid:TDWCAI6TPiUHBCCkalofBDbGdhA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80W03 uniprotkb:D3Z4R4 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 intact:EBI-26673198|ensembl:ENSMUSP00000095588|ensembl:ENSMUSP00000101701 psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:d3z4r4_mouse(display_long)|uniprotkb:Nkx6-2(gene name)|psi-mi:Nkx6-2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675958|imex:IM-28774-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) ensembl:ENSMUSG00000041309(gene)|ensembl:ENSMUST00000097974(transcript)|ensembl:ENSMUST00000106095(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010455"(positive regulation of cell fate commitment)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031641"(regulation of myelination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_899071.2|entrezgene/locuslink:14912(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rogid:8uwDwWnjt2gFmwB282nVs56MH/I10090 rigid:Kg7hElHf9+TQ8APYJoMZgLSP/Hg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTU0 uniprotkb:Q80W03 intact:EBI-8339791|intact:MINT-4107441|uniprotkb:Q6A023|uniprotkb:Q80WA8|ensembl:ENSMUSP00000047308 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 psi-mi:phf2_mouse(display_long)|uniprotkb:Phf2(gene name)|psi-mi:Phf2(display_short)|uniprotkb:GRC5(gene name synonym)|uniprotkb:Kiaa0662(gene name synonym)|uniprotkb:PHD finger protein 2(gene name synonym) psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675966|imex:IM-28774-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035208.2|ensembl:ENSMUSG00000038025(gene)|ensembl:ENSMUST00000035540(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035574"(histone H4-K20 demethylation)|go:"GO:0035575"(histone H4-methyl-lysine-20 demethylase activity)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|mint:Q9WTU0|reactome:R-MMU-3214842|entrezgene/locuslink:18676(identity) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2RoS6FXstspu+TN1DwCkVySJlUI10090 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rigid:0GKfBZTz9fnt0bxRZXmbkYFz2qE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80W03 uniprotkb:P40645 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 intact:EBI-3505685|uniprotkb:Q62250|uniprotkb:Q9QWS5|ensembl:ENSMUSP00000072583|ensembl:ENSMUSP00000129027 psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:sox6_mouse(display_long)|uniprotkb:Sox6(gene name)|psi-mi:Sox6(display_short)|uniprotkb:Sox-6(gene name synonym)|uniprotkb:SOX-LZ(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675974|imex:IM-28774-3325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) refseq:XP_011240009.1|refseq:XP_011240013.1|refseq:NP_035575.1|ensembl:ENSMUSG00000051910(gene)|ensembl:ENSMUST00000072804(transcript)|ensembl:ENSMUST00000166207(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0021529"(spinal cord oligodendrocyte cell differentiation)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051216"(cartilage development)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR027153|interpro:IPR036910|reactome:R-MMU-3769402|refseq:NP_001264255.1|refseq:NP_001264257.1|entrezgene/locuslink:20679(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rogid:/75ue2MRV87y9md6501iiDfVHJQ10090 rigid:ubpTJwOspHjIOMba/ENaVqa0OGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:P18847 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676254|imex:IM-28774-3337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N|entrezgene/locuslink:467(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rigid:ywbJ/teFqdr4E+ELFW7CcZkOIQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:P84022 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676246|imex:IM-28774-3335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|entrezgene/locuslink:4088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:CDZjfIeMSbLxFvIPUqFYcDDIdpY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:Q15797 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-1567153|uniprotkb:Q16636|uniprotkb:D3DNZ9|uniprotkb:A8KAJ0|uniprotkb:Q9UFT8|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:smad1_human(display_long)|uniprotkb:Mad-related protein 1(gene name synonym)|uniprotkb:SMAD family member 1(gene name synonym)|uniprotkb:Transforming growth factor-beta-signaling protein 1(gene name synonym)|uniprotkb:JV4-1(gene name synonym)|uniprotkb:SMAD1(gene name)|psi-mi:SMAD1(display_short)|uniprotkb:BSP1(gene name synonym)|uniprotkb:MADH1(gene name synonym)|uniprotkb:MADR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676238|imex:IM-28774-1585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) refseq:XP_006714280.1|refseq:NP_001003688.1|refseq:NP_005891.1|refseq:XP_011530263.1|refseq:XP_011530264.1|refseq:XP_011530265.1|refseq:XP_011530266.1|refseq:XP_005263049.1|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568|dip:DIP-38538N|ensembl:ENSG00000170365(gene)|ensembl:ENST00000302085(transcript)|ensembl:ENST00000394092(transcript)|ensembl:ENST00000515385(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007276"(gamete generation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042592"(homeostatic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15797|rcsb pdb:1KHU|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LAZ|rcsb pdb:2LB0|rcsb pdb:2LB1|rcsb pdb:3Q47|rcsb pdb:3Q4A|rcsb pdb:5ZOK|reactome:R-HSA-201451|reactome:R-HSA-5689880|reactome:R-HSA-8941326|entrezgene/locuslink:4086(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:cdDNFpwLw2+hPeP0l6ArvDs3LMo9606 rigid:pvJ8ohZf6BmNFOmlCYHvvJq0Tx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:Q92769 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676230|imex:IM-28774-2899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|entrezgene/locuslink:3066(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:ZDRCyOIFTyOqgcHG/tHULigKIWc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:O95696 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676222|imex:IM-28774-3333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1|entrezgene/locuslink:23774(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rigid:IHDphWDBhVghs0vVVLHHV56cL1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:Q9UKW6 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-747605|uniprotkb:O95175|uniprotkb:Q8N2K9|uniprotkb:Q96QY3|uniprotkb:Q9UKW5|uniprotkb:A8K452|uniprotkb:A6XAE6|ensembl:ENSP00000311010 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:elf5_human(display_long)|uniprotkb:E74-like factor 5(gene name synonym)|uniprotkb:Epithelium-specific Ets transcription factor 2(gene name synonym)|uniprotkb:Epithelium-restricted ESE-1-related Ets factor(gene name synonym)|uniprotkb:ELF5(gene name)|psi-mi:ELF5(display_short)|uniprotkb:ESE2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676214|imex:IM-28774-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) refseq:NP_001413.1|refseq:NP_938195.1|refseq:NP_001230009.1|refseq:NP_001230010.1|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033069|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WWX|go:"GO:0030154"(cell differentiation)|ensembl:ENSG00000135374(gene)|ensembl:ENST00000312319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:2001(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:FrgZm5Qx+Ox5xjZJ+rtnGdEbRB49606 rigid:OM3uPqnIbdDgrsVuEfivvXmW+fE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:Q13133 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676206|imex:IM-28774-2897 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|entrezgene/locuslink:10062(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606 rigid:5JE3HFuw4RMFnqW3o3uc4CPEUa4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y4E5 uniprotkb:Q8N653 intact:EBI-747230|uniprotkb:Q5VVF1|uniprotkb:Q8N380|uniprotkb:Q8TD15|uniprotkb:Q9NQM1|uniprotkb:Q86YE4|uniprotkb:Q9C0G1|intact:EBI-1104831|uniprotkb:Q5VVE9|ensembl:ENSP00000359740 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zn451_human(display_long)|uniprotkb:KIAA1702(gene name synonym)|uniprotkb:Coactivator for steroid receptors(gene name synonym)|uniprotkb:ZNF451(gene name)|psi-mi:ZNF451(display_short)|uniprotkb:COASTER(gene name synonym)|uniprotkb:KIAA0576(gene name synonym)|uniprotkb:Zinc finger protein 451(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ZNF451(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676198|imex:IM-28774-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026794.1|refseq:NP_056370.2|ensembl:ENSG00000112200(gene)|ensembl:ENST00000370706(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:2000616"(negative regulation of histone H3-K9 acetylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041192|mint:Q9Y4E5|rcsb pdb:5D2M|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|dip:DIP-51264N|entrezgene/locuslink:26036(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WNBXLe+XYJ7nSNhgXZL3keG5OYo9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:8BiQ7ir8//+V9cCo2KA1pXdLjmY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y4E5 uniprotkb:P61457 intact:EBI-747230|uniprotkb:Q5VVF1|uniprotkb:Q8N380|uniprotkb:Q8TD15|uniprotkb:Q9NQM1|uniprotkb:Q86YE4|uniprotkb:Q9C0G1|intact:EBI-1104831|uniprotkb:Q5VVE9|ensembl:ENSP00000359740 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zn451_human(display_long)|uniprotkb:KIAA1702(gene name synonym)|uniprotkb:Coactivator for steroid receptors(gene name synonym)|uniprotkb:ZNF451(gene name)|psi-mi:ZNF451(display_short)|uniprotkb:COASTER(gene name synonym)|uniprotkb:KIAA0576(gene name synonym)|uniprotkb:Zinc finger protein 451(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ZNF451(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676190|imex:IM-28774-2895 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026794.1|refseq:NP_056370.2|ensembl:ENSG00000112200(gene)|ensembl:ENST00000370706(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:2000616"(negative regulation of histone H3-K9 acetylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041192|mint:Q9Y4E5|rcsb pdb:5D2M|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|dip:DIP-51264N|entrezgene/locuslink:26036(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WNBXLe+XYJ7nSNhgXZL3keG5OYo9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:jYLROkaC+Yc6Y3BQkn9uFapNplo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:Q9H2G9 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676182|imex:IM-28774-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606 rigid:qNNzfgwHba/NWZQsfwPQVONilIg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:Q9Y6K9 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676174|imex:IM-28774-2487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:put9lYP4rtbwOQgOvuyUJfxVsQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:Q8N653 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676166|imex:IM-28774-2893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:/Ro4Wx5bIGpuHgMeSoyx0MHpd7s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:Q8N653 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676158|imex:IM-28774-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:/Ro4Wx5bIGpuHgMeSoyx0MHpd7s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BI67 uniprotkb:P10751 intact:EBI-26675731|ensembl:ENSMUSP00000051069|ensembl:ENSMUSP00000113774|uniprotkb:Q8BI98|uniprotkb:Q8BIB7 intact:EBI-26675794|ensembl:ENSMUSP00000051861|uniprotkb:B2RTF0|uniprotkb:P10752|uniprotkb:P10753|uniprotkb:Q505E4|uniprotkb:Q6PDR5|uniprotkb:Q8BSI2|uniprotkb:Q8C3R5 psi-mi:zn473_mouse(display_long)|uniprotkb:Zinc finger protein 100(gene name synonym)|uniprotkb:Znf473(gene name)|psi-mi:Znf473(display_short)|uniprotkb:Zfp100(gene name synonym)|uniprotkb:Zfp473(gene name synonym) psi-mi:zfp11_mouse(display_long)|uniprotkb:Zinc finger protein Krox-6.1A/6.1B+/6.1B-(gene name synonym)|uniprotkb:Zfp11(gene name)|psi-mi:Zfp11(display_short)|uniprotkb:Krox-6.1a(gene name synonym)|uniprotkb:Krox-6.1b(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675819|imex:IM-28774-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048012(gene)|ensembl:ENSMUST00000060270(transcript)|ensembl:ENSMUST00000120074(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-111367|reactome:R-MMU-212436|reactome:R-MMU-73856|reactome:R-MMU-77588|refseq:NP_001276765.1|refseq:NP_001276766.1|refseq:NP_001276767.1|refseq:NP_001276768.1|refseq:NP_848849.2|refseq:XP_006540941.1|refseq:XP_006540942.1|refseq:XP_006540944.1|refseq:XP_006540945.1|entrezgene/locuslink:243963(identity) ensembl:ENSMUSG00000051034(gene)|ensembl:ENSMUST00000049778(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_766050.1|entrezgene/locuslink:22648(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SXcsZ7mDh8icrmCDxmh9pnyZ6/810090 rogid:FwOticXsX/o0BQh/pzDHpcoAzaA10090 rigid:pQ3Ka6Gs49nrFsFJLYJZDn4DT1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:P15976 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676142|imex:IM-28774-2073 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:qMZOrimbCDYvGXM5iK1dTOI/o70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYH5 uniprotkb:Q8IYM9 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 intact:EBI-954123|ensembl:ENSP00000369299|uniprotkb:Q15521|uniprotkb:Q05CQ0 psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:tri22_human(display_long)|uniprotkb:RING finger protein 94(gene name synonym)|uniprotkb:50 kDa-stimulated trans-acting factor(gene name synonym)|uniprotkb:Staf-50(gene name synonym)|uniprotkb:Tripartite motif-containing protein 22(gene name synonym)|uniprotkb:TRIM22(gene name)|psi-mi:TRIM22(display_short)|uniprotkb:RNF94(gene name synonym)|uniprotkb:STAF50(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM22(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676134|imex:IM-28774-1157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) ensembl:ENSG00000132274(gene)|ensembl:ENST00000379965(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015030"(Cajal body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035827|interpro:IPR043136|mint:Q8IYM9|reactome:R-HSA-877300|go:"GO:0051607"(defense response to virus)|refseq:NP_001186502.1|refseq:NP_006065.2|entrezgene/locuslink:10346(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rogid:8CNTleevg3ll6+eu/3p28ysv1M09606 rigid:XVQZAnK6whDcXwrpU0d3t/bNZW0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WX92 uniprotkb:P18615 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676126|imex:IM-28774-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N|entrezgene/locuslink:25920(identity) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N|entrezgene/locuslink:7936(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rigid:fREs1n1uv0yMBd8a9jeYUEjra4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WX92 uniprotkb:Q15744 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676118|imex:IM-28774-2891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N|entrezgene/locuslink:25920(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:yEs/brdrdH3ucrMInmvhP5pRkm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95238 uniprotkb:P35227 intact:EBI-12811275|ensembl:ENSP00000363149|uniprotkb:B4DWH8|uniprotkb:F5H778 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:spdef_human(display_long)|uniprotkb:SPDEF(gene name)|psi-mi:SPDEF(display_short)|uniprotkb:PDEF(gene name synonym)|uniprotkb:PSE(gene name synonym)|uniprotkb:Prostate epithelium-specific Ets transcription factor(gene name synonym)|uniprotkb:Prostate-derived Ets factor(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676110|imex:IM-28774-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124664(gene)|ensembl:ENST00000374037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010455"(positive regulation of cell fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1YO5|rcsb pdb:2DKX|refseq:NP_001239223.1|refseq:NP_036523.1|entrezgene/locuslink:25803(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|entrezgene/locuslink:7703(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0u1q4JCEO5hrwapuegAMhx/do189606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rigid:eoGTetBRT+SaFVTpYlCslJK81bI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58929 uniprotkb:E9Q6D6 intact:EBI-8412438|uniprotkb:Q6PCY0|intact:MINT-4096213|ensembl:ENSMUSP00000037075 intact:EBI-26676063|ensembl:ENSMUSP00000064226 psi-mi:gmeb2_mouse(display_long)|uniprotkb:Gmeb2(gene name)|psi-mi:Gmeb2(display_short) psi-mi:e9q6d6_mouse(display_long)|uniprotkb:Zfp277(gene name)|psi-mi:Zfp277(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676102|imex:IM-28774-1155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937812.1|refseq:XP_006500665.1|refseq:XP_006500666.1|refseq:XP_006500667.1|refseq:XP_006500668.1|ensembl:ENSMUSG00000038705(gene)|ensembl:ENSMUST00000049032(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|mint:P58929|entrezgene/locuslink:229004(identity) ensembl:ENSMUSG00000055917(gene)|ensembl:ENSMUST00000069692(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_766163.2|entrezgene/locuslink:246196(identity) - comment:mint|function:"Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VJzQzt5Zcio5zedRCftz7yyZJ/810090 rogid:nC7gyCW69ziug7qiHBBiTM3hOvM10090 rigid:4Fy1XQZvgYCgrizSPhw7CtTrHJQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:E9Q6D6 uniprotkb:P15806 intact:EBI-26676063|ensembl:ENSMUSP00000064226 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:e9q6d6_mouse(display_long)|uniprotkb:Zfp277(gene name)|psi-mi:Zfp277(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676094|imex:IM-28774-3331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055917(gene)|ensembl:ENSMUST00000069692(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_766163.2|entrezgene/locuslink:246196(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nC7gyCW69ziug7qiHBBiTM3hOvM10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:9xVDCoKCX5orQDX6ZTGG80G6SgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:E9Q6D6 uniprotkb:Q07279 intact:EBI-26676063|ensembl:ENSMUSP00000064226 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:e9q6d6_mouse(display_long)|uniprotkb:Zfp277(gene name)|psi-mi:Zfp277(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676086|imex:IM-28774-2071 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055917(gene)|ensembl:ENSMUST00000069692(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_766163.2|entrezgene/locuslink:246196(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nC7gyCW69ziug7qiHBBiTM3hOvM10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:nOEJXpBLCI78i0pc7hBi3y+mTRk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:E9Q6D6 uniprotkb:Q00322 intact:EBI-26676063|ensembl:ENSMUSP00000064226 intact:EBI-15611593|ensembl:ENSMUSP00000148145|uniprotkb:Q3U937|uniprotkb:Q8BW92 psi-mi:e9q6d6_mouse(display_long)|uniprotkb:Zfp277(gene name)|psi-mi:Zfp277(display_short) psi-mi:cebpd_mouse(display_long)|uniprotkb:C/EBP-related protein 3(gene name synonym)|uniprotkb:Cebpd(gene name)|psi-mi:Cebpd(display_short)|uniprotkb:Crp3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676078|imex:IM-28774-2485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055917(gene)|ensembl:ENSMUST00000069692(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_766163.2|entrezgene/locuslink:246196(identity) ensembl:ENSMUSG00000071637(gene)|ensembl:ENSMUST00000096232(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|refseq:NP_031705.3|dip:DIP-41645N|entrezgene/locuslink:12609(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nC7gyCW69ziug7qiHBBiTM3hOvM10090 rogid:aCmCPifzzDnsat5YKja5onlnM6E10090 rigid:wH030EzwEihWVNVV1QW002XxxKY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96LI5 uniprotkb:Q8N653 intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676055|imex:IM-28774-3329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N|entrezgene/locuslink:246175(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2Y605zw41TOo2ATkUM/7ToUb6449606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:kaBFSZm6yu2hgGUm8p72utQYqxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K5B9 uniprotkb:P70662 intact:EBI-26676025|ensembl:ENSMUSP00000072333|ensembl:ENSMUSP00000073522 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:q8k5b9_mouse(display_long)|uniprotkb:Tgif2lx2(gene name)|psi-mi:Tgif2lx2(display_short)|uniprotkb:Tgif2lx1(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676047|imex:IM-28774-3327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000100133(gene)|ensembl:ENSMUSG00000100194(gene)|ensembl:ENSMUST00000072518(transcript)|ensembl:ENSMUST00000073857(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001136222.1|refseq:NP_694749.1|entrezgene/locuslink:245583(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:45TWmqae36TQs8o4QtXtz0Kbpn810090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:M4YUmw1O/x0aYaAmg6q0rQWsbms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80W03 uniprotkb:Q8VHS6 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 intact:EBI-26675998|ensembl:ENSMUSP00000031696|ensembl:ENSMUSP00000112965|uniprotkb:Q8CDP8 psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:asb15_mouse(display_long)|uniprotkb:Asb15(gene name)|psi-mi:Asb15(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676017|imex:IM-28774-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) ensembl:ENSMUSG00000029685(gene)|ensembl:ENSMUST00000031696(transcript)|ensembl:ENSMUST00000117688(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|refseq:NP_543123.2|refseq:XP_011239391.1|entrezgene/locuslink:78910(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rogid:k90YXTebsFC0kF2V8wAQe54DFVM10090 rigid:y8X7ZngT0aKyJMglKMqweBVHikw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q80W03 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675990|imex:IM-28774-1153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rigid:+Ae3B0z+koxUHWMcRw30RAySkRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K284 uniprotkb:Q80W03 intact:EBI-8412484|uniprotkb:Q8CAL9|intact:MINT-4137479|ensembl:ENSMUSP00000056719 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 psi-mi:tf3c1_mouse(display_long)|uniprotkb:Gtf3c1(gene name)|psi-mi:Gtf3c1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym) psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26675982|imex:IM-28774-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_997122.1|ensembl:ENSMUSG00000032777(gene)|ensembl:ENSMUST00000055506(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007309(B-block binding subunit of TFIIIC)|interpro:IPR035625|interpro:IPR044210|mint:Q8K284|reactome:R-MMU-76061|reactome:R-MMU-76066|entrezgene/locuslink:233863(identity) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) - comment:mint|function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vL28aV6mHktcbaTvhC+U3jxtrAY10090 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rigid:1SXIYaYv9sRotKnceACLVYNmP74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:P40763 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676262|imex:IM-28774-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|entrezgene/locuslink:6774(identity) - - crc64:6C00632211C8012D figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:iSGPQIcsnzMM+XgzYMS8SWHDPZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:P36402 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-2119465|uniprotkb:Q86WR9|uniprotkb:Q9UKI4|uniprotkb:B3KSH3 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:tcf7_human(display_long)|uniprotkb:TCF7(gene name)|psi-mi:TCF7(display_short)|uniprotkb:TCF1(gene name synonym)|uniprotkb:T-cell-specific transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676270|imex:IM-28774-1587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) refseq:NP_001128323.2|refseq:NP_003193.2|refseq:NP_963963.1|refseq:NP_963965.1|refseq:NP_998813.1|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|refseq:XP_006714747.1|interpro:IPR024940|refseq:NP_001333379.1|interpro:IPR028785|refseq:NP_001333354.1|interpro:IPR027397|mint:P36402|interpro:IPR036910|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016604"(nuclear body)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0042492"(gamma-delta T cell differentiation)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-8951430|entrezgene/locuslink:6932(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:kmnoxa0P36UuMRl1UelvPXxOdBo9606 rigid:8H+uae2rzrHAs1WkjaZJckbAA/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75177 uniprotkb:P56524 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606 psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676278|imex:IM-28774-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|entrezgene/locuslink:9759(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rogid:EJhE8LikofmF9H8ubNsola4pSpc9606 rigid:E2NJeDvtikOwBy1lpBJ+NJz26DQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q9HC78 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-6427565|ensembl:ENSP00000419153|ensembl:ENSP00000501561|ensembl:ENSP00000502480|uniprotkb:Q9Y410|uniprotkb:Q8N6R5|uniprotkb:Q63HP6 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:zbt20_human(display_long)|uniprotkb:ZBTB20(gene name)|psi-mi:ZBTB20(display_short)|uniprotkb:DPZF(gene name synonym)|uniprotkb:Dendritic-derived BTB/POZ zinc finger protein(gene name synonym)|uniprotkb:ZNF288(gene name synonym)|uniprotkb:Zinc finger protein 288(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676286|imex:IM-28774-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) ensembl:ENSG00000181722(gene)|ensembl:ENST00000474710(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENST00000675478(transcript)|ensembl:ENST00000676079(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001157814.1|refseq:NP_001157815.1|refseq:NP_001157816.1|refseq:NP_001157817.1|refseq:NP_001157818.1|refseq:NP_001157819.1|refseq:NP_056457.3|refseq:NP_001335729.1|refseq:NP_001335731.1|refseq:NP_001335732.1|refseq:NP_001335733.1|refseq:NP_001335734.1|entrezgene/locuslink:26137(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:Z/fzrsssrqW+AamsDtYfFFUyj389606 rigid:b7WR3LEykkXvfhBgtNJPgPdNKlg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HC78 uniprotkb:P37231 intact:EBI-6427565|ensembl:ENSP00000419153|ensembl:ENSP00000501561|ensembl:ENSP00000502480|uniprotkb:Q9Y410|uniprotkb:Q8N6R5|uniprotkb:Q63HP6 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:zbt20_human(display_long)|uniprotkb:ZBTB20(gene name)|psi-mi:ZBTB20(display_short)|uniprotkb:DPZF(gene name synonym)|uniprotkb:Dendritic-derived BTB/POZ zinc finger protein(gene name synonym)|uniprotkb:ZNF288(gene name synonym)|uniprotkb:Zinc finger protein 288(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676294|imex:IM-28774-2077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000181722(gene)|ensembl:ENST00000474710(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENST00000675478(transcript)|ensembl:ENST00000676079(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001157814.1|refseq:NP_001157815.1|refseq:NP_001157816.1|refseq:NP_001157817.1|refseq:NP_001157818.1|refseq:NP_001157819.1|refseq:NP_056457.3|refseq:NP_001335729.1|refseq:NP_001335731.1|refseq:NP_001335732.1|refseq:NP_001335733.1|refseq:NP_001335734.1|entrezgene/locuslink:26137(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Z/fzrsssrqW+AamsDtYfFFUyj389606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:BbcdIyVlDz86sX+3NJVTZ+LFMek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C0J6 uniprotkb:P15806 intact:EBI-26676381|ensembl:ENSMUSP00000138351|uniprotkb:Q8BWN1 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:swahc_mouse(display_long)|uniprotkb:Ankyrin repeat domain-containing protein 57(gene name synonym)|uniprotkb:Protein sosondowah homolog C(gene name synonym)|uniprotkb:Ankrd57(gene name synonym)|uniprotkb:Sowahc(gene name)|psi-mi:Sowahc(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676394|imex:IM-28774-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000098188(gene)|ensembl:ENSMUST00000182161(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9035034|refseq:NP_766527.3|entrezgene/locuslink:268301(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7cfpv5+QNwaqWv/FAcGBGIiRzJI10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:xPc93VmlafGrC7udTz0oEo7WuHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z125 uniprotkb:O35613 intact:EBI-26676310|uniprotkb:Q91W70 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 psi-mi:cr3l1_mouse(display_long)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)|uniprotkb:Creb3l1(gene name)|psi-mi:Creb3l1(display_short)|uniprotkb:Oasis(gene name synonym) psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676349|imex:IM-28774-3339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_036087.2|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|entrezgene/locuslink:26427(identity) refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095|entrezgene/locuslink:13163(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KCUX+dHUywlFuaEcUIIEW9YDyWQ10090 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 rigid:4vFcs2820A1x8I3U3St1HfPt0hQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NY61 uniprotkb:O75177 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676357|imex:IM-28774-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|entrezgene/locuslink:26574(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:7nF/5DE4qOYnIDjIlYyVq6CeQUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NY61 uniprotkb:Q8N653 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676365|imex:IM-28774-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|entrezgene/locuslink:26574(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:JvmLokQxhs4SGVyD0x26MDPYWHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80X44 uniprotkb:Q61545 intact:EBI-7616854|uniprotkb:Q3UIB7|uniprotkb:Q8CJC9|intact:MINT-5188934|uniprotkb:Q7TPC4|ensembl:ENSMUSP00000079592 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zbt24_mouse(display_long)|uniprotkb:Zinc finger protein 450(gene name synonym)|uniprotkb:Bone morphogenetic protein-induced factor 1(gene name synonym)|uniprotkb:Brain-specific protein 1(gene name synonym)|uniprotkb:Zbtb24(gene name)|psi-mi:Zbtb24(display_short)|uniprotkb:Bif1(gene name synonym)|uniprotkb:Bsg1(gene name synonym)|uniprotkb:Znf450(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676373|imex:IM-28774-3341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_700447.2|refseq:NP_001264158.1|refseq:NP_001264159.1|ensembl:ENSMUSG00000019826(gene)|ensembl:ENSMUST00000080771(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q80X44|rcsb pdb:6ML2|rcsb pdb:6ML3|rcsb pdb:6ML4|rcsb pdb:6ML5|rcsb pdb:6ML6|rcsb pdb:6ML7|entrezgene/locuslink:268294(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - comment:mint|function:May be involved in BMP2-induced transcription - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:V3w4OFeP+rXfAhr/3hYbcToisMw10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:T+XRdwNYIVWPmCHoyFkqzImUgMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV1 uniprotkb:O60667 intact:EBI-12111292|ensembl:ENSP00000306163|uniprotkb:Q3B778|uniprotkb:Q5T456|uniprotkb:Q70EZ9|uniprotkb:Q8WUD7|uniprotkb:Q96MG0|uniprotkb:Q9NQC9 intact:EBI-2809270|ensembl:ENSP00000356058|uniprotkb:A8K7J2|uniprotkb:B7Z6Z0|uniprotkb:D9MWM3 psi-mi:ankr2_human(display_long)|uniprotkb:ANKRD2(gene name)|psi-mi:ANKRD2(display_short)|uniprotkb:ARPP(gene name synonym)|uniprotkb:Skeletal muscle ankyrin repeat protein(gene name synonym) psi-mi:faim3_human(display_long)|uniprotkb:FCMR(gene name)|psi-mi:FCMR(display_short)|uniprotkb:FAIM3(gene name synonym)|uniprotkb:IgM Fc fragment receptor(gene name synonym)|uniprotkb:Regulator of Fas-induced apoptosis Toso(gene name synonym)|uniprotkb:TOSO(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676302|imex:IM-28774-2901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165887(gene)|ensembl:ENST00000307518(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016605"(PML body)|go:"GO:0031674"(I band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR036770|refseq:NP_001333726.1|refseq:NP_001123453.1|refseq:NP_001278147.1|refseq:NP_065082.2|refseq:NP_001278148.2|entrezgene/locuslink:26287(identity) ensembl:ENSG00000162894(gene)|ensembl:ENST00000367091(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_001135945.1|refseq:NP_001180267.1|refseq:NP_005440.1|entrezgene/locuslink:9214(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XKdt7K4PJe3I+OhZuEz9turolqI9606 rogid:Yt3zQ0fOJl3PACiIx5FPWFC6eQI9606 rigid:rPb2qOpo0/DMH1QFs1VlhRwZWu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:P97480 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-349175|uniprotkb:P97768|ensembl:ENSMUSP00000078157|uniprotkb:G5E8I5 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:eya3_mouse(display_long)|uniprotkb:Eya3(gene name)|psi-mi:Eya3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676593|imex:IM-28774-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) refseq:NP_034296.2|ensembl:ENSMUST00000079157(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR028479|interpro:IPR038102|interpro:IPR042577|reactome:R-MMU-5693565|ensembl:ENSMUSG00000028886(gene)|entrezgene/locuslink:14050(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:0yaKFTJm3uCQYXt/sgj+aSmZOVI10090 rigid:cWM6stnJEHtER5dbvLBQS8uRLr4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:P19091 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-1776062|ensembl:ENSMUSP00000052648 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:andr_mouse(display_long)|uniprotkb:Ar(gene name)|psi-mi:Ar(display_short)|uniprotkb:Nr3c4(gene name synonym)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676585|imex:IM-28774-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) refseq:NP_038504.1|dip:DIP-41803N|ensembl:ENSMUSG00000046532(gene)|ensembl:ENSMUST00000052837(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007620"(copulation)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008049"(male courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0009987"(cellular process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0016607"(nuclear speck)|go:"GO:0019098"(reproductive behavior)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0032553"(ribonucleotide binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046661"(male sex differentiation)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060406"(positive regulation of penile erection)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060685"(regulation of prostatic bud formation)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061458"(reproductive system development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P19091|rcsb pdb:2QPY|reactome:R-MMU-3371497|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-5625886|reactome:R-MMU-5689880|reactome:R-MMU-8940973|entrezgene/locuslink:11835(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:R9c9Nn/MNbBhJH78pXj3MTaiGGM10090 rigid:Jftv3ffS6PCpZDBVMk7/Eb8PErQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75529 uniprotkb:Q15744 intact:EBI-1785876|uniprotkb:Q8IW31|uniprotkb:Q5TDI6|uniprotkb:Q5TDI5|ensembl:ENSP00000258281 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:taf5l_human(display_long)|uniprotkb:TAF5L(gene name)|psi-mi:TAF5L(display_short)|uniprotkb:PAF65B(gene name synonym)|uniprotkb:PCAF-associated factor 65 beta(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676577|imex:IM-28774-3345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020418.1|refseq:NP_055224.1|refseq:XP_005273156.1|dip:DIP-28147N|ensembl:ENSG00000135801(gene)|ensembl:ENST00000258281(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR001680(WD40 repeat)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|interpro:IPR037826|mint:O75529|reactome:R-HSA-3214847|entrezgene/locuslink:27097(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3D2y64CWMvwok3BvV2CpH6iX84E9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:fcE+9MW8Xb0QvysouATDicOPMe4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3X904 uniprotkb:Q3U1N2 intact:EBI-26667657|ensembl:ENSMUSP00000033731 intact:EBI-645275|uniprotkb:Q9ESZ4|uniprotkb:Q925C2|ensembl:ENSMUSP00000023100 psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:srbp2_mouse(display_long)|uniprotkb:Sterol regulatory element-binding transcription factor 2(gene name synonym)|uniprotkb:Srebf2(gene name)|psi-mi:Srebf2(display_short)|uniprotkb:Srebp2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676569|imex:IM-28774-1591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) refseq:NP_150087.1|ensembl:ENSMUSG00000022463(gene)|ensembl:ENSMUST00000023100(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009725"(response to hormone)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-MMU-1655829|go:"GO:0008593"(regulation of Notch signaling pathway)|entrezgene/locuslink:20788(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rogid:uDjwj6tUHAmJizC11vcpYHK/sUc10090 rigid:nqCr7wlyLvxsIGkf8kUfuOgoD+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7KZF4 uniprotkb:Q8N653 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676561|imex:IM-28774-2903 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N|entrezgene/locuslink:27044(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:n/kSNQQIPtXojgYb44ZnjCBY4Ds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2Y4 uniprotkb:P09016 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676553|imex:IM-28774-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1|entrezgene/locuslink:27033(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:7vej3voDVb7RF1DcyrPEP5f5peU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2Y4 uniprotkb:P23769 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676545|imex:IM-28774-1165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1|entrezgene/locuslink:27033(identity) refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|entrezgene/locuslink:2624(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 rigid:D5Ah+faiwECp0LfilTuS0Wq2im0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2Y4 uniprotkb:Q15723 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 intact:EBI-956941|uniprotkb:E9PCX3|uniprotkb:Q15724|uniprotkb:Q15725|uniprotkb:Q6P1K5|ensembl:ENSP00000368868 psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:elf2_human(display_long)|uniprotkb:ELF2(gene name)|psi-mi:ELF2(display_short)|uniprotkb:NERF(gene name synonym)|uniprotkb:E74-like factor 2(gene name synonym)|uniprotkb:New ETS-related factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676537|imex:IM-28774-2493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1|entrezgene/locuslink:27033(identity) refseq:NP_001263387.1|refseq:NP_006865.1|refseq:NP_973728.1|refseq:NP_001263386.1|refseq:NP_001263388.1|refseq:XP_005262861.1|refseq:NP_001317965.1|ensembl:ENSG00000109381(gene)|ensembl:ENST00000379550(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR022084|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8939245|entrezgene/locuslink:1998(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rogid:I+5r30P0sfIJfJSYkJwjpbWxUnE9606 rigid:x3cLxRt9uW6nayjcIXa/sqTvyas false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:Q9CZK6 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-26675873|ensembl:ENSMUSP00000023157|uniprotkb:Q6ZPF6|uniprotkb:Q80X46 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:anks3_mouse(display_long)|uniprotkb:Anks3(gene name)|psi-mi:Anks3(display_short)|uniprotkb:Kiaa1977(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676529|imex:IM-28774-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) ensembl:ENSMUSG00000022515(gene)|ensembl:ENSMUST00000023157(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|refseq:NP_082577.2|entrezgene/locuslink:72615(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:LRIwqpLLTOJZzsXDuttcg12w99k10090 rigid:h1QMkhpre/L/lMsgQBOaJz9OfOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:Q91VN1 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-6123187|uniprotkb:Q5MDG8|uniprotkb:Q9WUQ0|ensembl:ENSMUSP00000064637|ensembl:ENSMUSP00000122579 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:znf24_mouse(display_long)|uniprotkb:Znf24(gene name)|psi-mi:Znf24(display_short)|uniprotkb:Hmcns(gene name synonym)|uniprotkb:Zfp191(gene name synonym)|uniprotkb:Hypomyelinated CNS protein(gene name synonym)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein ZF-12(gene name synonym)|uniprotkb:Zfp24(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676521|imex:IM-28774-2083 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) refseq:XP_006526199.1|refseq:XP_006526200.1|refseq:NP_067534.2|ensembl:ENSMUSG00000051469(gene)|ensembl:ENSMUST00000066497(transcript)|ensembl:ENSMUST00000153337(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:59057(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:tkEyJw4DyBCe5XTRLcVNp3bgYjo10090 rigid:thWi3N6QNC+bGP++cQu02UkuNXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:Q91VN1 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-6123187|uniprotkb:Q5MDG8|uniprotkb:Q9WUQ0|ensembl:ENSMUSP00000064637|ensembl:ENSMUSP00000122579 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:znf24_mouse(display_long)|uniprotkb:Znf24(gene name)|psi-mi:Znf24(display_short)|uniprotkb:Hmcns(gene name synonym)|uniprotkb:Zfp191(gene name synonym)|uniprotkb:Hypomyelinated CNS protein(gene name synonym)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein ZF-12(gene name synonym)|uniprotkb:Zfp24(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676513|imex:IM-28774-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) refseq:XP_006526199.1|refseq:XP_006526200.1|refseq:NP_067534.2|ensembl:ENSMUSG00000051469(gene)|ensembl:ENSMUST00000066497(transcript)|ensembl:ENSMUST00000153337(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:59057(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:tkEyJw4DyBCe5XTRLcVNp3bgYjo10090 rigid:thWi3N6QNC+bGP++cQu02UkuNXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:O88609 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-13951208|uniprotkb:Q0VEN6 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676505|imex:IM-28774-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rigid:L33D+eu12GaYefZ0CgVUHs/MnJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:Q9WUH2 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676497|imex:IM-28774-2491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rigid:esrEBXUI3UYGZHn4j3gSo4eB4hU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:O55203 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676489|imex:IM-28774-2081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:bqe92SFwqOxX3HMUdFbq9ixisz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:P70662 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676481|imex:IM-28774-1163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:CipkOwMU+XAgXYh2HER6qAF+e6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8C9M8 uniprotkb:Q9CXV0 intact:EBI-26676450|ensembl:ENSMUSP00000039073 intact:EBI-26666142|ensembl:ENSMUSP00000034869|uniprotkb:G5E888 psi-mi:q8c9m8_mouse(display_long)|uniprotkb:Zfp446(gene name)|psi-mi:Zfp446(display_short) psi-mi:isl2_mouse(display_long)|uniprotkb:Isl2(gene name)|psi-mi:Isl2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676473|imex:IM-28774-1161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033961(gene)|ensembl:ENSMUST00000045810(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_001162033.1|refseq:NP_001162034.1|refseq:NP_780767.1|entrezgene/locuslink:269870(identity) interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:3MMK|rcsb pdb:6CME|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|ensembl:ENSMUSG00000032318(gene)|ensembl:ENSMUST00000034869(transcript)|refseq:NP_081673.2|entrezgene/locuslink:104360(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/0wpYT00qpbTNmu3d14tOif83Lg10090 rogid:1c2rTe1ctia50vPVvGLnTS1Smng10090 rigid:mxdFqqjbzGkK1TqCTY7z2h9u7TA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60381 uniprotkb:Q9GZV1 intact:EBI-954175|ensembl:ENSP00000222574|ensembl:ENSP00000418738|ensembl:ENSP00000420500|ensembl:ENSP00000491311|ensembl:ENSP00000492167|ensembl:ENSP00000492343|uniprotkb:Q8TBM1|uniprotkb:Q8TE93|uniprotkb:Q96AJ2|uniprotkb:B3KVB7 intact:EBI-12111292|ensembl:ENSP00000306163|uniprotkb:Q3B778|uniprotkb:Q5T456|uniprotkb:Q70EZ9|uniprotkb:Q8WUD7|uniprotkb:Q96MG0|uniprotkb:Q9NQC9 psi-mi:hbp1_human(display_long)|uniprotkb:HMG box transcription factor 1(gene name synonym)|uniprotkb:High mobility group box transcription factor 1(gene name synonym)|uniprotkb:HBP1(gene name)|psi-mi:HBP1(display_short) psi-mi:ankr2_human(display_long)|uniprotkb:ANKRD2(gene name)|psi-mi:ANKRD2(display_short)|uniprotkb:ARPP(gene name synonym)|uniprotkb:Skeletal muscle ankyrin repeat protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676442|imex:IM-28774-1589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105856(gene)|ensembl:ENSG00000283847(gene)|ensembl:ENST00000222574(transcript)|ensembl:ENST00000468410(transcript)|ensembl:ENST00000485846(transcript)|ensembl:ENST00000638303(transcript)|ensembl:ENST00000638893(transcript)|ensembl:ENST00000640195(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036096|interpro:IPR036910|interpro:IPR039655|rcsb pdb:2E6O|rcsb pdb:3QVE|refseq:NP_036389.2|refseq:NP_001231191.1|refseq:XP_005250323.1|refseq:XP_005250324.1|refseq:XP_016867456.1|entrezgene/locuslink:26959(identity) ensembl:ENSG00000165887(gene)|ensembl:ENST00000307518(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016605"(PML body)|go:"GO:0031674"(I band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR036770|refseq:NP_001333726.1|refseq:NP_001123453.1|refseq:NP_001278147.1|refseq:NP_065082.2|refseq:NP_001278148.2|entrezgene/locuslink:26287(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:w0Y0uk7CSIHtVWindV1UDg04WBA9606 rogid:XKdt7K4PJe3I+OhZuEz9turolqI9606 rigid:IRrW1isP/1hyXuz/cb+LAhdir2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZPI0 uniprotkb:P15806 intact:EBI-3043943|ensembl:ENSMUSP00000026865|ensembl:ENSMUSP00000127113|ensembl:ENSMUSP00000131441|ensembl:ENSMUSP00000128152|uniprotkb:Q6IE84|uniprotkb:Q8C7S6|uniprotkb:Q8CFM2|uniprotkb:Q8R362 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:jade1_mouse(display_long)|uniprotkb:Jade1(gene name)|psi-mi:Jade1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:Kiaa1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:Phf17(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676434|imex:IM-28774-2079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025764(gene)|ensembl:ENSMUST00000026865(transcript)|ensembl:ENSMUST00000163764(transcript)|ensembl:ENSMUST00000168086(transcript)|ensembl:ENSMUST00000170711(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|reactome:R-MMU-3214847|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_001123656.1|refseq:NP_001123657.1|refseq:NP_001123658.1|refseq:NP_758507.3|entrezgene/locuslink:269424(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jW5NLu5NDMYd7VoBHg3QAlLxlNI10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:MpF7RJJ+/8ZU/7xeY/yey0+KBck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00288 uniprotkb:Q6ZPI0 intact:EBI-1395397|uniprotkb:Q6GU20|uniprotkb:P97342|ensembl:ENSMUSP00000028355 intact:EBI-3043943|ensembl:ENSMUSP00000026865|ensembl:ENSMUSP00000127113|ensembl:ENSMUSP00000131441|ensembl:ENSMUSP00000128152|uniprotkb:Q6IE84|uniprotkb:Q8C7S6|uniprotkb:Q8CFM2|uniprotkb:Q8R362 psi-mi:pax8_mouse(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:jade1_mouse(display_long)|uniprotkb:Jade1(gene name)|psi-mi:Jade1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:Kiaa1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:Phf17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676426|imex:IM-28774-2489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035170.1|ensembl:ENSMUSG00000026976(gene)|ensembl:ENSMUST00000028355(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|entrezgene/locuslink:18510(identity) ensembl:ENSMUSG00000025764(gene)|ensembl:ENSMUST00000026865(transcript)|ensembl:ENSMUST00000163764(transcript)|ensembl:ENSMUST00000168086(transcript)|ensembl:ENSMUST00000170711(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|reactome:R-MMU-3214847|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_001123656.1|refseq:NP_001123657.1|refseq:NP_001123658.1|refseq:NP_758507.3|entrezgene/locuslink:269424(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:41aRv6r+djf0uC8katu9eOUnmJs10090 rogid:jW5NLu5NDMYd7VoBHg3QAlLxlNI10090 rigid:BiaQepAx4HpaCpSubvvfeo9+otY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZPI0 uniprotkb:Q8K5B8 intact:EBI-3043943|ensembl:ENSMUSP00000026865|ensembl:ENSMUSP00000127113|ensembl:ENSMUSP00000131441|ensembl:ENSMUSP00000128152|uniprotkb:Q6IE84|uniprotkb:Q8C7S6|uniprotkb:Q8CFM2|uniprotkb:Q8R362 intact:EBI-26668950|ensembl:ENSMUSP00000051003 psi-mi:jade1_mouse(display_long)|uniprotkb:Jade1(gene name)|psi-mi:Jade1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:Kiaa1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:Phf17(gene name synonym) psi-mi:hxc12_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.8(gene name synonym)|uniprotkb:Hoxc12(gene name)|psi-mi:Hoxc12(display_short)|uniprotkb:Hox-3.8(gene name synonym)|uniprotkb:Hoxc-12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676418|imex:IM-28774-3343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025764(gene)|ensembl:ENSMUST00000026865(transcript)|ensembl:ENSMUST00000163764(transcript)|ensembl:ENSMUST00000168086(transcript)|ensembl:ENSMUST00000170711(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|reactome:R-MMU-3214847|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_001123656.1|refseq:NP_001123657.1|refseq:NP_001123658.1|refseq:NP_758507.3|entrezgene/locuslink:269424(identity) ensembl:ENSMUSG00000050328(gene)|ensembl:ENSMUST00000055562(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034593.1|entrezgene/locuslink:15421(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jW5NLu5NDMYd7VoBHg3QAlLxlNI10090 rogid:PAHUpQimuoe8IfMJoiPbnA0o7SI10090 rigid:P5JHOaJqbaAnF50ZrcUDJvzj/3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZPI0 uniprotkb:P09631 intact:EBI-3043943|ensembl:ENSMUSP00000026865|ensembl:ENSMUSP00000127113|ensembl:ENSMUSP00000131441|ensembl:ENSMUSP00000128152|uniprotkb:Q6IE84|uniprotkb:Q8C7S6|uniprotkb:Q8CFM2|uniprotkb:Q8R362 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:jade1_mouse(display_long)|uniprotkb:Jade1(gene name)|psi-mi:Jade1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:Kiaa1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:Phf17(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676410|imex:IM-28774-1159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025764(gene)|ensembl:ENSMUST00000026865(transcript)|ensembl:ENSMUST00000163764(transcript)|ensembl:ENSMUST00000168086(transcript)|ensembl:ENSMUST00000170711(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|reactome:R-MMU-3214847|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_001123656.1|refseq:NP_001123657.1|refseq:NP_001123658.1|refseq:NP_758507.3|entrezgene/locuslink:269424(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jW5NLu5NDMYd7VoBHg3QAlLxlNI10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:fxEwDMnCIPbksU3S68+Op45UgmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZPI0 uniprotkb:F8VPR5 intact:EBI-3043943|ensembl:ENSMUSP00000026865|ensembl:ENSMUSP00000127113|ensembl:ENSMUSP00000131441|ensembl:ENSMUSP00000128152|uniprotkb:Q6IE84|uniprotkb:Q8C7S6|uniprotkb:Q8CFM2|uniprotkb:Q8R362 intact:EBI-10989694|ensembl:ENSMUSP00000023165 psi-mi:jade1_mouse(display_long)|uniprotkb:Jade1(gene name)|psi-mi:Jade1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:Kiaa1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:Phf17(gene name synonym) psi-mi:f8vpr5_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676402|imex:IM-28774-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025764(gene)|ensembl:ENSMUST00000026865(transcript)|ensembl:ENSMUST00000163764(transcript)|ensembl:ENSMUST00000168086(transcript)|ensembl:ENSMUST00000170711(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|reactome:R-MMU-3214847|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_001123656.1|refseq:NP_001123657.1|refseq:NP_001123658.1|refseq:NP_758507.3|entrezgene/locuslink:269424(identity) refseq:NP_001020603.1|ensembl:ENSMUSG00000022521(gene)|ensembl:ENSMUST00000023165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:12914(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jW5NLu5NDMYd7VoBHg3QAlLxlNI10090 rogid:9K1igrA8QbILB/vG1/XLKh9kzJM10090 rigid:/DqI3FV6huCkH5CYEGkYn6oS+4g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q9DBA9 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-6260822|uniprotkb:O35637 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:tf2h1_mouse(display_long)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Gtf2h1(gene name)|psi-mi:Gtf2h1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676609|imex:IM-28774-2087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|refseq:NP_001278004.1|interpro:IPR035925|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|refseq:NP_032212.3|interpro:IPR027079|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|entrezgene/locuslink:14884(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:kCRvc9Bheu2o11ISottCk0cgERI10090 rigid:573osu5UUNkNoM2kyGUynYXDpCY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q61221 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-298954|ensembl:ENSMUSP00000021530|uniprotkb:O08741|uniprotkb:O08993|uniprotkb:Q61664|uniprotkb:Q61665|uniprotkb:Q8C681|uniprotkb:Q8CC19|uniprotkb:Q8CCB6|uniprotkb:Q8R385|uniprotkb:Q9CYA8 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:hif1a_mouse(display_long)|uniprotkb:Hif1a(gene name)|psi-mi:Hif1a(display_short)|uniprotkb:ARNT-interacting protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676617|imex:IM-28774-1593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000021109(gene)|ensembl:ENSMUST00000021530(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060992"(response to fungicide)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q61221|rcsb pdb:4ZPR|reactome:R-MMU-1234158|reactome:R-MMU-1234174|reactome:R-MMU-1234176|reactome:R-MMU-5689880|reactome:R-MMU-8857538|reactome:R-MMU-8951664|refseq:NP_001300848.1|refseq:NP_001300849.1|refseq:NP_034561.2|refseq:XP_017170450.1|dip:DIP-31083N|entrezgene/locuslink:15251(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:1jBCL7bIWP7x+b9k/mCB131AQuA10090 rigid:fa2J9YsCXxigw/fz0VnZvTAl5rw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q6GTZ3 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-26669132 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:q6gtz3_mouse(display_long)|uniprotkb:Id1(gene name)|psi-mi:Id1(display_short)|uniprotkb:Idb1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676625|imex:IM-28774-2089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_034625.1|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|entrezgene/locuslink:15901(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:IRUXStmLzIzQ5jb8Aw8r0MhfKPc10090 rigid:Q8VC2Ozx5Iu0Bkhtb1l64gOHzF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q64287 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676633|imex:IM-28774-2091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N|entrezgene/locuslink:16364(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 rigid:kpSWcV2by4JlBCD53jTzSWnwOxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:P97471 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-5259270|uniprotkb:Q6GTP6|uniprotkb:Q9CW56|ensembl:ENSMUSP00000025393|ensembl:ENSMUSP00000110589 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:smad4_mouse(display_long)|uniprotkb:Smad4(gene name)|psi-mi:Smad4(display_short)|uniprotkb:Dpc4(gene name synonym)|uniprotkb:Madh4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4 homolog(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676641|imex:IM-28774-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) refseq:NP_032566.2|dip:DIP-29718N|ensembl:ENSMUSG00000024515(gene)|ensembl:ENSMUST00000025393(transcript)|ensembl:ENSMUST00000114939(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001822"(kidney development)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003360"(brainstem development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007369"(gastrulation)|go:"GO:0007411"(axon guidance)|go:"GO:0007492"(endoderm development)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031005"(filamin binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042060"(wound healing)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P97471|rcsb pdb:3QSV|reactome:R-MMU-1181150|reactome:R-MMU-1502540|reactome:R-MMU-201451|reactome:R-MMU-2173789|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-5689880|reactome:R-MMU-8941326|reactome:R-MMU-8941855|reactome:R-MMU-9617828|entrezgene/locuslink:17128(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:IJFXHvSWr9ahHMgHAekwlFtH57w10090 rigid:9vPeTHnYTI0JlB3wcxc68wndwIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:E9Q7L6 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-26670490|ensembl:ENSMUSP00000107857 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:e9q7l6_mouse(display_long)|uniprotkb:Foxn2(gene name)|psi-mi:Foxn2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676601|imex:IM-28774-2085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000034998(gene)|ensembl:ENSMUST00000112238(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_851305.2|refseq:XP_006523714.1|refseq:XP_006523715.1|refseq:XP_006523716.1|refseq:XP_006523717.1|entrezgene/locuslink:14236(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:0Q80fJTtlauGRomropH9xTNH9kA10090 rigid:2JRiZERjExeMfCwGKXD//AmvAlc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:O14978 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-744493|uniprotkb:O43387|uniprotkb:Q96H95|uniprotkb:B2R634|ensembl:ENSP00000219069 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:zn263_human(display_long)|uniprotkb:Zinc finger protein FPM315(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 12(gene name synonym)|uniprotkb:ZNF263(gene name)|psi-mi:ZNF263(display_short)|uniprotkb:FPM315(gene name synonym)|uniprotkb:ZKSCAN12(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676919|imex:IM-28774-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_005732.2|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030752|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|ensembl:ENSG00000006194(gene)|ensembl:ENST00000219069(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:10127(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:6W8A+hmUjdSzgIWT6wSAcwPaMLU9606 rigid:0Nb2kLbNd5QOO0Y5z3OIxnTCbE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42586 uniprotkb:O55144 intact:EBI-8412526|intact:MINT-4103861|ensembl:ENSMUSP00000069666 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:nkx22_mouse(display_long)|uniprotkb:Nkx2-2(gene name)|psi-mi:Nkx2-2(display_short)|uniprotkb:Nkx-2.2(gene name synonym)|uniprotkb:Nkx2b(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog B(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676649|imex:IM-28774-2905 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237651.1|refseq:NP_035049.1|refseq:XP_006498961.1|refseq:XP_006498962.1|refseq:XP_006498963.1|ensembl:ENSMUSG00000027434(gene)|ensembl:ENSMUST00000067075(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003327"(type B pancreatic cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021529"(spinal cord oligodendrocyte cell differentiation)|go:"GO:0021530"(spinal cord oligodendrocyte cell fate specification)|go:"GO:0021554"(optic nerve development)|go:"GO:0030154"(cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032570"(response to progesterone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048565"(digestive tract development)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0060580"(ventral spinal cord interneuron fate determination)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:P42586|entrezgene/locuslink:18088(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - comment:mint|function:May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AMtGRyHWqO8spBmrL6YQZIGqiUQ10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:GJQWbML/LhVINqkAgU2O6YNSl3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q8R0B5 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-26670824|ensembl:ENSMUSP00000112532 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676657|imex:IM-28774-3347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rigid:z+ZQk4WA2/wBJHeYy+k+pXaQr6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:O35984 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-1373614|ensembl:ENSMUSP00000040464 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:pbx2_mouse(display_long)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Pbx2(gene name)|psi-mi:Pbx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676665|imex:IM-28774-1595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) refseq:NP_059491.1|ensembl:ENSMUSG00000034673(gene)|ensembl:ENSMUST00000038149(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|entrezgene/locuslink:18515(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:EoCd0crtktG/RBDDCiOSNP0O2vc10090 rigid:pxUKypemeVXSa1Lkg6EYTjEYnTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:O35973 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-1266764|uniprotkb:B1ASX0|ensembl:ENSMUSP00000021271|ensembl:ENSMUSP00000132635 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:per1_mouse(display_long)|uniprotkb:Per1(gene name)|psi-mi:Per1(display_short)|uniprotkb:Per(gene name synonym)|uniprotkb:Rigui(gene name synonym)|uniprotkb:Circadian clock protein PERIOD 1(gene name synonym)|uniprotkb:Circadian pacemaker protein Rigui(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676673|imex:IM-28774-1167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) refseq:NP_001152839.1|refseq:NP_035195.2|refseq:XP_006532543.1|dip:DIP-38519N|ensembl:ENSMUSG00000020893(gene)|ensembl:ENSMUST00000021271(transcript)|ensembl:ENSMUST00000166748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051591"(response to cAMP)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|mint:O35973|rcsb pdb:4DJ2|entrezgene/locuslink:18626(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:r2joaV40f8H8SBm7c+fmZ9fPdC410090 rigid:N31nKo5QnFGQd1CV/4YwMZiP/xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q64701 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-1213109|uniprotkb:Q3U1D4|ensembl:ENSMUSP00000029170 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:rbl1_mouse(display_long)|uniprotkb:Rbl1(gene name)|psi-mi:Rbl1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676681|imex:IM-28774-2907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) refseq:NP_001132988.1|refseq:NP_035379.2|ensembl:ENSMUSG00000027641(gene)|ensembl:ENSMUST00000029170(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|reactome:R-MMU-2173796|reactome:R-MMU-69231|reactome:R-MMU-1538133|entrezgene/locuslink:19650(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:EDpIg76rLvKX1D7ZX/Obu/ArqMw10090 rigid:CRS86K0MLMdtHGP91pMBr5hXdrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:O08674 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-26676689|ensembl:ENSMUSP00000017151 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:rbpjl_mouse(display_long)|uniprotkb:Transcription factor RBP-L(gene name synonym)|uniprotkb:Rbpjl(gene name)|psi-mi:Rbpjl(display_short)|uniprotkb:Rbpl(gene name synonym)|uniprotkb:Rbpsuhl(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676718|imex:IM-28774-1597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000017007(gene)|ensembl:ENSMUST00000017151(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|refseq:NP_033062.1|entrezgene/locuslink:19668(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:h1kKyLVRnA4jfwPuAKlppeTQ+gw10090 rigid:weZs8Wtzr/FuC36TgCAFlus5ITE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:A4QPD3 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-26676726|ensembl:ENSMUSP00000099928 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:a4qpd3_mouse(display_long)|uniprotkb:Rel(gene name)|psi-mi:Rel(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676755|imex:IM-28774-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000020275(gene)|ensembl:ENSMUST00000102864(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030505|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|interpro:IPR042845|refseq:NP_033070.2|entrezgene/locuslink:19696(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:+ZOsI/t9cx8uPhk6I1RZy7AyBRc10090 rigid:Jh4qnh0BbAME3EB6FRZ0a8Ej70s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:O70306 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-26676763|ensembl:ENSMUSP00000029462|uniprotkb:O54840|uniprotkb:Q5GBG1 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:tbx15_mouse(display_long)|uniprotkb:MmTBx8(gene name synonym)|uniprotkb:T-box transcription factor TBX14(gene name synonym)|uniprotkb:Tbx15(gene name)|psi-mi:Tbx15(display_short)|uniprotkb:Tbx14(gene name synonym)|uniprotkb:Tbx8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676794|imex:IM-28774-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000027868(gene)|ensembl:ENSMUST00000029462(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|refseq:NP_033349.2|entrezgene/locuslink:21384(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:iqsactegqxe1N1o5Agsdq06uJqg10090 rigid:fdVcjxiQ2RRC+VUdN7itclNlGxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55144 uniprotkb:Q62219 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 intact:EBI-642844|ensembl:ENSMUSP00000132100|uniprotkb:Q3YBY7|uniprotkb:Q3YBY8|uniprotkb:Q3YBZ0|uniprotkb:Q3YBZ1|uniprotkb:Q3YBZ3|uniprotkb:Q3YBZ4|uniprotkb:Q3YBZ5|uniprotkb:Q3YBZ6 psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:tgfi1_mouse(display_long)|uniprotkb:Tgfb1i1(gene name)|psi-mi:Tgfb1i1(display_short)|uniprotkb:Ara55(gene name synonym)|uniprotkb:Hydrogen peroxide-inducible clone 5 protein(gene name synonym)|uniprotkb:Androgen receptor-associated protein of 55 kDa(gene name synonym)|uniprotkb:TGF beta-stimulated clone 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676802|imex:IM-28774-2909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) ensembl:ENSMUSG00000030782(gene)|ensembl:ENSMUST00000167965(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009408"(response to heat)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|refseq:NP_001276479.1|refseq:NP_001276481.1|refseq:NP_001276482.1|refseq:XP_006507630.1|go:"GO:0050681"(androgen receptor binding)|go:"GO:0070411"(I-SMAD binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017305(Leupaxin)|mint:Q62219|go:"GO:0048495"(Roundabout binding)|entrezgene/locuslink:21804(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rogid:bh/xIQopXbPvHwdsY0wpv6OehT810090 rigid:tNkT0zKOqiv1dctPbFlEkbuEpjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:O35137 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676810|imex:IM-28774-2495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:MNUd6OABua/JAv5C3MxcrFi2ir4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:Q64317 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676818|imex:IM-28774-2911 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:NybjdYRHUTHT+qKJ2hytSNJo5DY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:Q61179 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-646653|ensembl:ENSMUSP00000120359 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:irf9_mouse(display_long)|uniprotkb:Isgf3g(gene name synonym)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:Irf9(gene name)|psi-mi:Irf9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676826|imex:IM-28774-1599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) refseq:NP_001152889.1|refseq:NP_001152890.1|refseq:NP_032420.1|reactome:R-MMU-909733|rcsb pdb:5OEN|ensembl:ENSMUSG00000002325(gene)|ensembl:ENSMUST00000130697(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5OEM|entrezgene/locuslink:16391(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:JHbDnrkiCtNJ9ktn4N0RE3lk21E10090 rigid:s/Y7A21RvVCY6AQApUYByoUpsbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:Q60867 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-309315|uniprotkb:Q545N9|uniprotkb:Q60897|ensembl:ENSMUSP00000040364 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:ndf1_mouse(display_long)|uniprotkb:Neurod1(gene name)|psi-mi:Neurod1(display_short)|uniprotkb:Neurod(gene name synonym)|uniprotkb:Beta-cell E-box transcriptional activator 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676834|imex:IM-28774-2913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) refseq:NP_035024.1|ensembl:ENSMUST00000041099(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|ensembl:ENSMUSG00000034701(gene)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR022575|interpro:IPR032652|go:"GO:0048562"(embryonic organ morphogenesis)|interpro:IPR036638|rcsb pdb:2QL2|go:"GO:0048666"(neuron development)|go:"GO:0048839"(inner ear development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060730"(regulation of intestinal epithelial structure maintenance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:18012(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:EOCuRlE8Dhx0NzTQi52B/NrEt0A10090 rigid:zmCvKTMrzwhjpPVxQPbsVUlNqF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:Q8R0B5 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-26670824|ensembl:ENSMUSP00000112532 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676842|imex:IM-28774-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rigid:83B+ICtZbYAuCYNfo0pB1zE5pLM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:Q63934 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-26671769|ensembl:ENSMUSP00000034115|uniprotkb:Q63954 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:po4f2_mouse(display_long)|uniprotkb:Brain-specific homeobox/POU domain protein 3B(gene name synonym)|uniprotkb:Pou4f2(gene name)|psi-mi:Pou4f2(display_short)|uniprotkb:Brn-3.2(gene name synonym)|uniprotkb:Brn3b(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676850|imex:IM-28774-2497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) ensembl:ENSMUSG00000031688(gene)|ensembl:ENSMUST00000034115(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048675"(axon extension)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090259"(regulation of retinal ganglion cell axon guidance)|go:"GO:1902870"(negative regulation of amacrine cell differentiation)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6804759|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|refseq:NP_620394.2|entrezgene/locuslink:18997(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:v7ZfH8cB4fqZSxUz060RJHwoTtM10090 rigid:hfpp3IVxzn4Td7b38qW5NAT8CHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUI0 uniprotkb:P50220 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676858|imex:IM-28774-2915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rigid:399Bnj+pnoI9K84bYTuPIv/IwYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8BV16 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26676866|ensembl:ENSMUSP00000078806 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:q8bv16_mouse(display_long)|uniprotkb:Zfp398(gene name)|psi-mi:Zfp398(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676887|imex:IM-28774-2499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000062519(gene)|ensembl:ENSMUST00000079881(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|reactome:R-MMU-212436|refseq:NP_081753.1|entrezgene/locuslink:272347(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:HpffkmDkFurn9SVWtpelbrrYx+810090 rigid:jKeQzKs5lxhGBVG3cxvTRtGrlDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:O95231 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-10191303|uniprotkb:Q32MZ3|ensembl:ENSP00000357556 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:ventx_human(display_long)|uniprotkb:VENTX(gene name)|psi-mi:VENTX(display_short)|uniprotkb:HPX42B(gene name synonym)|uniprotkb:VENT homeobox homolog(gene name synonym)|uniprotkb:VENT-like homeobox protein 2(gene name synonym)|uniprotkb:VENTX2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676895|imex:IM-28774-1601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) refseq:NP_055283.1|ensembl:ENSG00000151650(gene)|ensembl:ENST00000325980(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|reactome:R-HSA-2559582|reactome:R-HSA-8853884|entrezgene/locuslink:27287(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:81Gb5z8qFplllUAcd8iScZNQZsE9606 rigid:0Yb1tc+Yt9yryFnMiCJsDQz6BH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95231 uniprotkb:Q04724 intact:EBI-10191303|uniprotkb:Q32MZ3|ensembl:ENSP00000357556 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:ventx_human(display_long)|uniprotkb:VENTX(gene name)|psi-mi:VENTX(display_short)|uniprotkb:HPX42B(gene name synonym)|uniprotkb:VENT homeobox homolog(gene name synonym)|uniprotkb:VENT-like homeobox protein 2(gene name synonym)|uniprotkb:VENTX2(gene name synonym) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676903|imex:IM-28774-1169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055283.1|ensembl:ENSG00000151650(gene)|ensembl:ENST00000325980(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|reactome:R-HSA-2559582|reactome:R-HSA-8853884|entrezgene/locuslink:27287(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:81Gb5z8qFplllUAcd8iScZNQZsE9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:plf8zflRrUBNCgwH2qFodA+xSUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95231 uniprotkb:Q04725 intact:EBI-10191303|uniprotkb:Q32MZ3|ensembl:ENSP00000357556 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 psi-mi:ventx_human(display_long)|uniprotkb:VENTX(gene name)|psi-mi:VENTX(display_short)|uniprotkb:HPX42B(gene name synonym)|uniprotkb:VENT homeobox homolog(gene name synonym)|uniprotkb:VENT-like homeobox protein 2(gene name synonym)|uniprotkb:VENTX2(gene name synonym) psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676911|imex:IM-28774-2917 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055283.1|ensembl:ENSG00000151650(gene)|ensembl:ENST00000325980(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|reactome:R-HSA-2559582|reactome:R-HSA-8853884|entrezgene/locuslink:27287(identity) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:81Gb5z8qFplllUAcd8iScZNQZsE9606 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rigid:PvvpX4uGjgUld9CI391RAjqVhco false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q99909 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-10295431|uniprotkb:O60223|uniprotkb:Q9BRW7|uniprotkb:Q5JQZ3|ensembl:ENSP00000298396 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:ssx3_human(display_long)|uniprotkb:SSX3(gene name)|psi-mi:SSX3(display_short)|uniprotkb:Cancer/testis antigen 5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676927|imex:IM-28774-1603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_066294.1|refseq:XP_011542187.1|ensembl:ENSG00000165584(gene)|ensembl:ENST00000298396(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:10214(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:jSB31TCCfnAP7jshF00a7bTb/sA9606 rigid:DlF9eYPIAhjDLMSWTE2b+ZwTgY0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q3KP44 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-14493093|uniprotkb:B3KVT8|uniprotkb:Q3KP45|uniprotkb:Q9HAD3|ensembl:ENSP00000342295 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:anr55_human(display_long)|uniprotkb:ANKRD55(gene name)|psi-mi:ANKRD55(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677111|imex:IM-28774-1177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) ensembl:ENSP00000342295|ensembl:ENST00000434982|ensembl:ENSP00000429421|refseq:NP_078945.2|refseq:XP_016865342.1|ensembl:ENSG00000164512(gene)|ensembl:ENST00000341048(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|entrezgene/locuslink:79722(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:r3JVaxGJQxLwfcO8GJuIZxeIZx49606 rigid:Ij+u/wRnO0iH7JSUkY82CV4jRGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9UMR3 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-21805318|uniprotkb:A4D1Y6|uniprotkb:Q000T4|uniprotkb:Q0IJ70|uniprotkb:Q0VAS1|uniprotkb:Q9Y2N5|ensembl:ENSP00000386170 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:tbx20_human(display_long)|uniprotkb:TBX20(gene name)|psi-mi:TBX20(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677079|imex:IM-28774-1175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_001071121.1|refseq:NP_001159692.1|ensembl:ENSG00000164532(gene)|ensembl:ENST00000408931(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001706"(endoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0001947"(heart looping)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003171"(atrioventricular valve development)|go:"GO:0003175"(tricuspid valve development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003193"(pulmonary valve formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006936"(muscle contraction)|go:"GO:0008015"(blood circulation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010991"(negative regulation of SMAD protein complex assembly)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035922"(foramen ovale closure)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0036306"(embryonic heart tube elongation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048370"(lateral mesoderm formation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060577"(pulmonary vein morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|entrezgene/locuslink:57057(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:OxFdxVbodOz9LU9o2yv+m3abkfk9606 rigid:TCBU0cfWU9JMDQInqnsyIAri9cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q15545 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677103|imex:IM-28774-3351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:6879(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rigid:sPg5UZuE9pkiuHxfIt+fCNLuF4M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:O60225 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-10186198|uniprotkb:Q5JQ59|uniprotkb:Q96AW3|uniprotkb:Q5JQ60|ensembl:ENSP00000290558 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:ssx5_human(display_long)|uniprotkb:SSX5(gene name)|psi-mi:SSX5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677095|imex:IM-28774-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_066295.3|refseq:NP_783729.1|refseq:XP_016885247.1|refseq:XP_011542251.1|ensembl:ENSG00000165583(gene)|ensembl:ENST00000347757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:6758(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:sVINA7fZyttxJg58NXmqzVL9PAc9606 rigid:+HOKFfCMqJiOF+OitwTXU3/LLhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35251 uniprotkb:Q8NBB4 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677087|imex:IM-28774-2927 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|entrezgene/locuslink:5981(identity) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rigid:7IX//BV4cSsh2mcsi594DJqBV4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9UNY4 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677127|imex:IM-28774-3353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4|entrezgene/locuslink:8458(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 rigid:h9Uj0tjdva2DX9XvzJW1QYXwnMo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9BZY9 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-747544|uniprotkb:Q53H52|uniprotkb:Q5RI37|uniprotkb:Q5SRJ7|uniprotkb:Q5SRJ8|uniprotkb:Q5SS28|uniprotkb:Q96AK4|uniprotkb:Q96AP8|uniprotkb:Q99579|uniprotkb:Q9BZY8|uniprotkb:A6NLX6|uniprotkb:A9R9Q4|ensembl:ENSP00000350182|ensembl:ENSP00000365924|ensembl:ENSP00000390551|ensembl:ENSP00000391685|ensembl:ENSP00000398677|ensembl:ENSP00000409501 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:tri31_human(display_long)|uniprotkb:TRIM31(gene name)|psi-mi:TRIM31(display_short)|uniprotkb:C6orf13(gene name synonym)|uniprotkb:RNF(gene name synonym)|uniprotkb:Tripartite motif-containing protein 31(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM31(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676935|imex:IM-28774-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_008959.3|ensembl:ENSG00000137397(gene)|ensembl:ENSG00000204616(gene)|ensembl:ENSG00000223531(gene)|ensembl:ENSG00000224168(gene)|ensembl:ENSG00000225130(gene)|ensembl:ENSG00000233573(gene)|ensembl:ENST00000357569(transcript)|ensembl:ENST00000376734(transcript)|ensembl:ENST00000433864(transcript)|ensembl:ENST00000445679(transcript)|ensembl:ENST00000449412(transcript)|ensembl:ENST00000453266(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020457|rcsb pdb:2YSJ|rcsb pdb:2YSL|reactome:R-HSA-877300|entrezgene/locuslink:11074(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:f7qMSpsjq1gDv+rl2o2BWpXhvKw9606 rigid:GjSq/cpawDBdnHUgsAPMjyBd2uY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P19447 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-1183307|uniprotkb:Q53QM0|ensembl:ENSP00000285398 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:ercc3_human(display_long)|uniprotkb:ERCC3(gene name)|psi-mi:ERCC3(display_short)|uniprotkb:XPB(gene name synonym)|uniprotkb:XPBC(gene name synonym)|uniprotkb:Basic transcription factor 2 89 kDa subunit(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 89 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein complementing XP-B cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group B-complementing protein(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676943|imex:IM-28774-2919 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_000113.1|ensembl:ENSG00000163161(gene)|ensembl:ENST00000285398(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|mint:P19447|rcsb pdb:4ERN|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-73863|dip:DIP-83N|entrezgene/locuslink:2071(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:KOM9+f636LHK8qfTFkLIm0X0VoY9606 rigid:Q/+4kRQK8P4KU1na4pFmtJArn6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q13573 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676951|imex:IM-28774-2501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N|entrezgene/locuslink:22938(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 rigid:p6PZdDqbNlsjL54ZvlHFpfTGxUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9Y2L8 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-2876965|intact:EBI-28975936|ensembl:ENSP00000322872|ensembl:ENSP00000377725|ensembl:ENSP00000392104|uniprotkb:A4D280|uniprotkb:D6W5S9 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:zksc5_human(display_long)|uniprotkb:ZKSCAN5(gene name)|psi-mi:ZKSCAN5(display_short)|uniprotkb:KIAA1015(gene name synonym)|uniprotkb:ZFP95(gene name synonym)|uniprotkb:Zinc finger protein 95 homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676959|imex:IM-28774-2093 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) ensembl:ENSG00000196652(gene)|ensembl:ENST00000326775(transcript)|ensembl:ENST00000394170(transcript)|ensembl:ENST00000451158(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q9Y2L8|rcsb pdb:2EM5|rcsb pdb:2EMM|rcsb pdb:2EMZ|rcsb pdb:2EN3|rcsb pdb:2EOM|rcsb pdb:2EON|rcsb pdb:2EOO|rcsb pdb:2YSO|rcsb pdb:2YTG|reactome:R-HSA-212436|go:"GO:0008270"(zinc ion binding)|ensembl:ENSP00000322872|ensembl:ENSP00000377725|ensembl:ENSP00000392104|refseq:NP_001305011.1|refseq:NP_001305012.1|refseq:NP_001305013.1|refseq:NP_055384.1|refseq:NP_659570.1|refseq:XP_016867407.1|refseq:XP_016867408.1|entrezgene/locuslink:23660(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:IGLnMrywMbMAwqoSnoXhPKm3Hus9606 rigid:vvMrScWPc62n9DyjDBnJJk2wPTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q96LI5 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676967|imex:IM-28774-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N|entrezgene/locuslink:246175(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:2Y605zw41TOo2ATkUM/7ToUb6449606 rigid:LA575+YsVzGY/VYByLg401iqQWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q96N95 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-12549639|ensembl:ENSP00000466500|uniprotkb:A1L3V0|uniprotkb:Q8NF98|uniprotkb:Q8TD80 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:zn396_human(display_long)|uniprotkb:ZNF396(gene name)|psi-mi:ZNF396(display_short)|uniprotkb:ZSCAN14(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 14(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676975|imex:IM-28774-1171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) ensembl:ENSG00000186496(gene)|ensembl:ENST00000589332(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016881176.1|refseq:XP_016881177.1|refseq:NP_001309215.1|refseq:NP_001309219.1|refseq:NP_001309220.1|refseq:NP_665699.1|refseq:XP_006722495.1|entrezgene/locuslink:252884(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:c9DHxkd1sWpSewmyzwJiHwFk6Ps9606 rigid:+y9w89QrJSnL7I3mBUb8vwpqx+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q8NBB4 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676983|imex:IM-28774-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rigid:Kq4DIDRIx4vNiBtbcR9hpnLINV8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P29083 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26676999|imex:IM-28774-2921 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:Mak68S/Ein96yiToABPk0AKFlU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P32780 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677007|imex:IM-28774-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N|entrezgene/locuslink:2965(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:RAJJZ8d9D/0pC3mWcH1ksS9YMio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q99743 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677015|imex:IM-28774-2503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:aF32vLpt7D6q5M1zAInEsQhqebU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9Y3C7 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677023|imex:IM-28774-1605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:51003(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rigid:ooEVb4WVZTpdNVNraPKOzL/BSlM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:O43660 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-1051504|uniprotkb:Q3KQY5|uniprotkb:Q8WUD8|uniprotkb:B3KMK4|ensembl:ENSP00000424417 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:plrg1_human(display_long)|uniprotkb:PLRG1(gene name)|psi-mi:PLRG1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677031|imex:IM-28774-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_001188493.1|refseq:NP_002660.1|ensembl:ENSG00000171566(gene)|ensembl:ENST00000499023(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:O43660|rcsb pdb:4YVD|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DH6|rcsb pdb:7DVQ|reactome:R-HSA-72163|interpro:IPR020472|entrezgene/locuslink:5356(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:TdZ60+R9eEw7Q0zgsHjv8DImHMA9606 rigid:ZJH2J2A5DmmPKwcoAQEU374iQyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P30876 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677039|imex:IM-28774-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N|entrezgene/locuslink:5431(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:L/KIrCEunMjjo9ePLQ7uE7aT8lQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:O15514 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677047|imex:IM-28774-2923 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N|entrezgene/locuslink:5433(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:4aRbx90vXpHUn+2SuyF7aLC7XoQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P19388 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677055|imex:IM-28774-2505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N|entrezgene/locuslink:5434(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:Eejqthj/aa8eqkVBPV62ZGYVD3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P37231 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677063|imex:IM-28774-2925 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:o1yUK7E7le7vueEW5Upo7vuR6+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9C0G0 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-5654914|uniprotkb:Q9H8A1|uniprotkb:Q96MY0|uniprotkb:B5MD54|uniprotkb:Q9NXD7|uniprotkb:Q9NXD4|ensembl:ENSP00000299687 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:zn407_human(display_long)|uniprotkb:KIAA1703(gene name synonym)|uniprotkb:ZNF407(gene name)|psi-mi:ZNF407(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677071|imex:IM-28774-3349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:XP_011524372.1|refseq:XP_011524370.1|refseq:NP_001139661.1|refseq:NP_001139662.1|refseq:NP_060227.2|refseq:XP_005266783.1|ensembl:ENSG00000215421(gene)|ensembl:ENST00000299687(transcript)|interpro:IPR036236|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:55628(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:1IwRCT+v3qYg2Ii3jabVzznKu8Y9606 rigid:POEVVO8kQZM3w9P9wx1eEYCYkzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9BPY8 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-10295883|uniprotkb:Q96CI1|uniprotkb:A8K0Z2|uniprotkb:G3V294|uniprotkb:E9PB55|uniprotkb:Q8N0V6|ensembl:ENSP00000315198|ensembl:ENSP00000337330|ensembl:ENSP00000370654|ensembl:ENSP00000422175|ensembl:ENSP00000424101|ensembl:ENSP00000451794|ensembl:ENSP00000452003|ensembl:ENSP00000452098|ensembl:ENSP00000452340 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:hop_human(display_long)|uniprotkb:HOPX(gene name)|psi-mi:HOPX(display_short)|uniprotkb:HOD(gene name synonym)|uniprotkb:HOP(gene name synonym)|uniprotkb:LAGY(gene name synonym)|uniprotkb:Lung cancer-associated Y protein(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Not expressed in choriocarcinoma protein 1(gene name synonym)|uniprotkb:OB1(gene name synonym)|uniprotkb:Odd homeobox protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677119|imex:IM-28774-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_001138931.1|refseq:NP_001138932.1|refseq:NP_115884.4|refseq:NP_631957.1|refseq:NP_631958.1|ensembl:ENSG00000171476(gene)|ensembl:ENST00000317745(transcript)|ensembl:ENST00000337881(transcript)|ensembl:ENST00000381255(transcript)|ensembl:ENST00000503639(transcript)|ensembl:ENST00000508121(transcript)|ensembl:ENST00000553379(transcript)|ensembl:ENST00000555760(transcript)|ensembl:ENST00000556376(transcript)|ensembl:ENST00000556614(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003166"(bundle of His development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016575"(histone deacetylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039162|refseq:XP_016864218.1|refseq:XP_016864219.1|refseq:XP_016864220.1|refseq:XP_016864221.1|refseq:XP_016864222.1|refseq:XP_016864223.1|entrezgene/locuslink:84525(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:/gi1nxWJWDhu+a3Lsjs+SORvACM9606 rigid:+XeQW5ege2Lesg3ir/JUDEd2N7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9UBL3 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677177|imex:IM-28774-2929 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|entrezgene/locuslink:9070(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rigid:t7gXNJlw09Oq/f1DRZL8sJ+qnhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q9UNS1 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-2212315|intact:EBI-2561400|uniprotkb:B2ZAV0|uniprotkb:O94802|uniprotkb:Q86VM1|uniprotkb:Q8IWH3|ensembl:ENSP00000450607 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:tim_human(display_long)|uniprotkb:TIMELESS(gene name)|psi-mi:TIMELESS(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:TIM1(gene name synonym)|uniprotkb:TIMELESS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677169|imex:IM-28774-3355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_003911.2|refseq:NP_001317224.1|dip:DIP-47395N|ensembl:ENSG00000111602(gene)|ensembl:ENST00000553532(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009582"(detection of abiotic stimulus)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043111"(replication fork arrest)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:1904976"(cellular response to bleomycin)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|rcsb pdb:4XHT|rcsb pdb:4XHU|rcsb pdb:4XHW|rcsb pdb:5MQI|rcsb pdb:6T9Q|rcsb pdb:6TAZ|reactome:R-HSA-5693607|entrezgene/locuslink:8914(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:lFzdtUFz91sT6BcYbkFDEmPU3KU9606 rigid:6MCSpEYz8lPt5RBVwYYQEHMbQZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q96T92 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-26677135|ensembl:ENSP00000306523|uniprotkb:A1L432|uniprotkb:J9Y024|uniprotkb:Q8N8K7|uniprotkb:Q96Q84 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:insm2_human(display_long)|uniprotkb:Zinc finger protein IA-6(gene name synonym)|uniprotkb:Nbla106(orf name)|uniprotkb:IA6(gene name synonym)|uniprotkb:INSM2(gene name)|psi-mi:INSM2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677161|imex:IM-28774-2507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) ensembl:ENSG00000168348(gene)|ensembl:ENST00000307169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR042972|refseq:NP_115983.3|entrezgene/locuslink:84684(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:UCuG0NGXLLU9A0QQPprurUxWkw89606 rigid:tDBDJRrNNnXAHNoU3ZyAwHh+Qm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:P08047 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677353|imex:IM-28774-1609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|entrezgene/locuslink:6667(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 rigid:2ge+8aYY+jT2o/ScGJv7NsJ4xaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:O00470 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677345|imex:IM-28774-1183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) refseq:NP_002389.1|ensembl:ENSG00000143995(gene)|ensembl:ENST00000272369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|entrezgene/locuslink:4211(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606 rigid:2kugMfWUzAXLaHZMCf2r5okgX1E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:Q9BUJ2 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677337|imex:IM-28774-2937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N|entrezgene/locuslink:11100(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 rigid:Mm4HE8pGdFKLjWbtm+HoNARCc0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:Q9UNN4 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677329|imex:IM-28774-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rigid:I5M1/nWAz0gvqzPVnhF6OxmsRqE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:O43711 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677321|imex:IM-28774-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rigid:F9UOn5ACddp/IkW3xEj71g529Z4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:Q7Z401 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-1046479|ensembl:ENSP00000396830|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|uniprotkb:E7EPL3 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677313|imex:IM-28774-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) ensembl:ENST00000431932(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|ensembl:ENSG00000174485(gene)|mint:Q7Z401|reactome:R-HSA-8876198|refseq:NP_001138295.1|refseq:NP_005839.3|refseq:XP_005254178.1|refseq:XP_016877352.1|entrezgene/locuslink:10260(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606 rigid:TX0ZJz7T3g0sGe37hmwT7cbmtUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:O60828 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-713867|uniprotkb:Q4VY25|uniprotkb:Q4VY26|uniprotkb:Q4VY27|uniprotkb:Q4VY29|uniprotkb:Q4VY30|uniprotkb:Q4VY34|uniprotkb:Q4VY35|uniprotkb:Q4VY36|uniprotkb:Q4VY37|uniprotkb:Q4VY38|uniprotkb:Q9GZP2|uniprotkb:Q9GZU4|uniprotkb:Q9GZZ4|ensembl:ENSP00000218224|ensembl:ENSP00000365747|ensembl:ENSP00000379985|ensembl:ENSP00000391759|ensembl:ENSP00000498362|uniprotkb:C9JQA1 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:pqbp1_human(display_long)|uniprotkb:Polyglutamine tract-binding protein 1(gene name synonym)|uniprotkb:38 kDa nuclear protein containing a WW domain(gene name synonym)|uniprotkb:PQBP1(gene name)|psi-mi:PQBP1(display_short)|uniprotkb:JM26(orf name)|uniprotkb:NPW38(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677305|imex:IM-28774-1181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) ensembl:ENSG00000102103(gene)|ensembl:ENST00000218224(transcript)|ensembl:ENST00000376563(transcript)|ensembl:ENST00000396763(transcript)|ensembl:ENST00000447146(transcript)|ensembl:ENST00000651767(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031175"(neuron projection development)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051607"(defense response to virus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:O60828|rcsb pdb:4BWQ|rcsb pdb:4BWS|rcsb pdb:4CDO|reactome:R-HSA-72163|refseq:NP_001027553.1|refseq:NP_001027554.1|refseq:NP_001027555.1|refseq:NP_001027556.1|refseq:NP_001161461.1|refseq:NP_001161462.1|refseq:NP_001161464.1|refseq:NP_005701.1|refseq:NP_652766.1|refseq:XP_016884696.1|refseq:XP_011542186.1|refseq:XP_005272628.1|refseq:XP_005272629.1|entrezgene/locuslink:10084(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:E4tMCoGbaqAfjU8QXbQzbAb8fGQ9606 rigid:zh9uFJiJLPlu6L1H4vUKZ6OxDQ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UL17 uniprotkb:O43248 intact:EBI-3922312|ensembl:ENSP00000177694 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:tbx21_human(display_long)|uniprotkb:TBX21(gene name)|psi-mi:TBX21(display_short)|uniprotkb:TBET(gene name synonym)|uniprotkb:TBLYM(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677297|imex:IM-28774-2097 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61303N|refseq:NP_037483.1|ensembl:ENSG00000073861(gene)|ensembl:ENST00000177694(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009615"(response to virus)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|entrezgene/locuslink:30009(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pBAiEOJJCYZznQ5p/T7l1lkBYfs9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:ovuOHNLuHgOMkhcKMcGmcrrHCg8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHV2 uniprotkb:Q15369 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677289|imex:IM-28774-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N|entrezgene/locuslink:6921(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:40dvjniwxY/UQiyoVREicctpWe09606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:HS/FqgVz/8NVPrlqKFWf5vNtlYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHV2 uniprotkb:Q9UKN5 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677281|imex:IM-28774-3359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3|entrezgene/locuslink:11108(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:40dvjniwxY/UQiyoVREicctpWe09606 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rigid:07pgsQn6+ZsJpIE2hizxrX+mqHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHV2 uniprotkb:Q7Z401 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 intact:EBI-1046479|ensembl:ENSP00000396830|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|uniprotkb:E7EPL3 psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677273|imex:IM-28774-2513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity) ensembl:ENST00000431932(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|ensembl:ENSG00000174485(gene)|mint:Q7Z401|reactome:R-HSA-8876198|refseq:NP_001138295.1|refseq:NP_005839.3|refseq:XP_005254178.1|refseq:XP_016877352.1|entrezgene/locuslink:10260(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:40dvjniwxY/UQiyoVREicctpWe09606 rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606 rigid:FmnRvv24AGj9+bNn7iR1DY8ne50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJW3 uniprotkb:Q9Y6K1 intact:EBI-740967|ensembl:ENSP00000486001|uniprotkb:Q9BUJ4|uniprotkb:E9PB42 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 psi-mi:dnm3l_human(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short) psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677265|imex:IM-28774-2935 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037501.2|refseq:NP_787063.1|ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|mint:Q9UJW3|rcsb pdb:2PV0|rcsb pdb:2PVC|rcsb pdb:2QRV|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:6U90|rcsb pdb:6U91|rcsb pdb:6W8B|rcsb pdb:6W89|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-5334118|dip:DIP-35238N|entrezgene/locuslink:29947(identity) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|entrezgene/locuslink:1788(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 rigid:xtS65NYj8oXf0JDw2e9FHKr9Ej0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJW3 uniprotkb:Q9Y6K1 intact:EBI-740967|ensembl:ENSP00000486001|uniprotkb:Q9BUJ4|uniprotkb:E9PB42 intact:EBI-923653|uniprotkb:Q8WXU9|uniprotkb:Q86XF5|uniprotkb:Q8IZV0|uniprotkb:Q86TE8|uniprotkb:E9PEB8|ensembl:ENSP00000264709|ensembl:ENSP00000324375 psi-mi:dnm3l_human(display_long)|uniprotkb:DNMT3L(gene name)|psi-mi:DNMT3L(display_short) psi-mi:dnm3a_human(display_long)|uniprotkb:DNMT3A(gene name)|psi-mi:DNMT3A(display_short)|uniprotkb:DNA methyltransferase HsaIIIA(gene name synonym)|uniprotkb:Cysteine methyltransferase DNMT3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677257|imex:IM-28774-3357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037501.2|refseq:NP_787063.1|ensembl:ENSG00000142182(gene)|ensembl:ENST00000628202(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1905642"(negative regulation of DNA methylation)|go:"GO:1905643"(positive regulation of DNA methylation)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR025766|interpro:IPR030486|interpro:IPR040552|mint:Q9UJW3|rcsb pdb:2PV0|rcsb pdb:2PVC|rcsb pdb:2QRV|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6KDA|rcsb pdb:6KDB|rcsb pdb:6KDL|rcsb pdb:6KDP|rcsb pdb:6KDT|rcsb pdb:6U8P|rcsb pdb:6U8V|rcsb pdb:6U8W|rcsb pdb:6U8X|rcsb pdb:6U90|rcsb pdb:6U91|rcsb pdb:6W8B|rcsb pdb:6W89|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-5334118|dip:DIP-35238N|entrezgene/locuslink:29947(identity) refseq:NP_001307821.1|refseq:NP_072046.2|refseq:NP_783328.1|refseq:NP_783329.1|refseq:XP_016859015.1|refseq:XP_016859016.1|refseq:XP_011530969.1|refseq:NP_001307822.1|refseq:NP_715640.2|refseq:XP_005264232.1|dip:DIP-38004N|refseq:XP_005264234.1|ensembl:ENSG00000119772(gene)|ensembl:ENST00000264709(transcript)|ensembl:ENST00000321117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033189"(response to vitamin A)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR000313(PWWP)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR018117|interpro:IPR025766|interpro:IPR029063|interpro:IPR030487|interpro:IPR040552|interpro:IPR044108|mint:Q9Y6K1|rcsb pdb:2QRV|rcsb pdb:3A1A|rcsb pdb:3A1B|rcsb pdb:3LLR|rcsb pdb:3SVM|rcsb pdb:4QBQ|rcsb pdb:4QBR|rcsb pdb:4QBS|rcsb pdb:4U7P|rcsb pdb:4U7T|rcsb pdb:5YX2|rcsb pdb:6BRR|rcsb pdb:6F57|rcsb pdb:6PA7|rcsb pdb:6W89|rcsb pdb:6W8B|rcsb pdb:6W8D|rcsb pdb:6W8J|reactome:R-HSA-212300|reactome:R-HSA-3214858|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|entrezgene/locuslink:1788(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gOKtRLyVrI+sdPALQgHEsazQF/g9606 rogid:rnq1Yv4tlQ1t9JXS3CfMmTlcPKE9606 rigid:xtS65NYj8oXf0JDw2e9FHKr9Ej0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UIV1 uniprotkb:P09016 intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677249|imex:IM-28774-2095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115|entrezgene/locuslink:29883(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:x9nNgAiI48n3Lq6WyV3JwynrED8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZI6 uniprotkb:Q9NZI6 intact:EBI-2795420|uniprotkb:Q4ZG43|ensembl:ENSP00000263707 intact:EBI-2795420|uniprotkb:Q4ZG43|ensembl:ENSP00000263707 psi-mi:tf2l1_human(display_long)|uniprotkb:TFCP2L1(gene name)|psi-mi:TFCP2L1(display_short)|uniprotkb:CRTR1(gene name synonym)|uniprotkb:LBP9(gene name synonym)|uniprotkb:CP2-related transcriptional repressor 1(gene name synonym)|uniprotkb:Transcription factor LBP-9(gene name synonym) psi-mi:tf2l1_human(display_long)|uniprotkb:TFCP2L1(gene name)|psi-mi:TFCP2L1(display_short)|uniprotkb:CRTR1(gene name synonym)|uniprotkb:LBP9(gene name synonym)|uniprotkb:CP2-related transcriptional repressor 1(gene name synonym)|uniprotkb:Transcription factor LBP-9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677233|imex:IM-28774-1179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055368.1|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007431"(salivary gland development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0045927"(positive regulation of growth)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037598|interpro:IPR041418|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000115112(gene)|ensembl:ENST00000263707(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|entrezgene/locuslink:29842(identity) refseq:NP_055368.1|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007431"(salivary gland development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0045927"(positive regulation of growth)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037598|interpro:IPR041418|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000115112(gene)|ensembl:ENST00000263707(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|entrezgene/locuslink:29842(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:H+UJmUmjBgENKqI86vGrljs7wyc9606 rogid:H+UJmUmjBgENKqI86vGrljs7wyc9606 rigid:9jRKG/TjA0IDPSb94q5yfRrvsig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NPI1 uniprotkb:P61457 intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677225|imex:IM-28774-2511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758|entrezgene/locuslink:29117(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:+nF6dap7ihF5gZY50vJkiPD+6GA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NPI1 uniprotkb:O43251 intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677217|imex:IM-28774-2931 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758|entrezgene/locuslink:29117(identity) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:oiBHcWC6mQRmhVrv5YacJo1s7oY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q99459 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677209|imex:IM-28774-1607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|entrezgene/locuslink:988(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 rigid:i1IM73T9RVIcVImcGFEaSM3KNUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:P51116 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677201|imex:IM-28774-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rigid:Gau8QsGYwNQgNdnYzfsDSC6Ubc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:O43513 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677193|imex:IM-28774-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:vCJzZeHi2NUyn6qgZLl9EHJdkew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NBB4 uniprotkb:Q13503 intact:EBI-5292994|uniprotkb:Q3B798|uniprotkb:Q6WLH8|uniprotkb:Q86WS8|ensembl:ENSP00000282326 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 psi-mi:zsca1_human(display_long)|uniprotkb:ZSCAN1(gene name)|psi-mi:ZSCAN1(display_short) psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677185|imex:IM-28774-2509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872378.3|ensembl:ENSG00000152467(gene)|ensembl:ENST00000282326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:284312(identity) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N|entrezgene/locuslink:9412(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WR2G0UBcX3kvOdwdBzRYAEmtJs09606 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rigid:wzeogNmYAA3sCr8G4SZ2RcUTorM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:Q04725 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677370|imex:IM-28774-2939 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rigid:wTjo7biAVKhKHtNUGC497aDXLto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:P51814 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-2681830|uniprotkb:Q9UMV8|uniprotkb:Q9UMV6|uniprotkb:A8K1V6|uniprotkb:Q9UMW1|uniprotkb:Q9UMC4|uniprotkb:B4DH01|uniprotkb:Q9UMV5|uniprotkb:Q9UMV9|uniprotkb:Q9UMW0|uniprotkb:Q96LE8|uniprotkb:Q9UMV7 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:znf41_human(display_long)|uniprotkb:ZNF41(gene name)|psi-mi:ZNF41(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677378|imex:IM-28774-1185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) refseq:NP_009061.1|refseq:NP_700359.1|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|reactome:R-HSA-212436|refseq:NP_001311068.1|refseq:NP_001311069.1|refseq:NP_001311070.1|refseq:NP_001311071.1|refseq:NP_001311072.1|refseq:NP_001311073.1|refseq:NP_001311074.1|refseq:NP_001311076.1|refseq:NP_001311077.1|refseq:NP_001311078.1|refseq:NP_001311079.1|refseq:NP_001311080.1|refseq:NP_001311081.1|refseq:NP_001311082.1|refseq:NP_001311083.1|refseq:NP_001311084.1|refseq:NP_001311085.1|refseq:NP_001311086.1|refseq:XP_006724613.1|refseq:XP_006724618.1|refseq:XP_016885299.1|refseq:XP_016885300.1|refseq:XP_016885301.1|refseq:XP_016885302.1|refseq:XP_016885303.1|refseq:XP_016885304.1|refseq:XP_016885305.1|refseq:XP_016885306.1|interpro:IPR036051|interpro:IPR036236|entrezgene/locuslink:7592(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:+xy2wZYA7AIWGXwXVZ8sVNLDJb89606 rigid:GTLcgvRUWzzF0ySQqaGPMyI/PCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:P06899 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677386|imex:IM-28774-2515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|entrezgene/locuslink:8970(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:Icv4uAXhXJuhXXopm4RVwyP+aAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P43241 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-26668158|ensembl:ENSMUSP00000031650 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:cdx2_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 2(gene name synonym)|uniprotkb:Cdx2(gene name)|psi-mi:Cdx2(display_short)|uniprotkb:Cdx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677394|imex:IM-28774-3361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) ensembl:ENSMUSG00000029646(gene)|ensembl:ENSMUST00000031650(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0060711"(labyrinthine layer development)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_031699.2|entrezgene/locuslink:12591(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:1XpCK7ehS+3cgrG8vncU1t2kkpQ10090 rigid:BQWAoGfoT91prSzOwaiLqzIWLN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43711 uniprotkb:Q04724 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677362|imex:IM-28774-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:jzjHAaVKAPEY407G6L+2zTWmM9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BLR9 uniprotkb:Q07279 intact:EBI-26677747|ensembl:ENSMUSP00000035326|uniprotkb:A1L3B7|uniprotkb:Q3U3G4 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:hif1n_mouse(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Hif1an(gene name)|psi-mi:Hif1an(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677785|imex:IM-28774-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036450(gene)|ensembl:ENSMUST00000040455(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|reactome:R-MMU-1234174|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|refseq:NP_795932.2|entrezgene/locuslink:319594(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KeIzXsW0VKPpWc2sdX+Q5qyYLZI10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:UF8e2vVG+tsz/vZT5bX6V4NyzzE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31276 uniprotkb:P27695 intact:EBI-2293590|uniprotkb:Q5BL02|uniprotkb:Q96J32|uniprotkb:Q9NR24|uniprotkb:Q9NYD5|ensembl:ENSP00000243056 intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979 psi-mi:hxc13_human(display_long)|uniprotkb:HOXC13(gene name)|psi-mi:HOXC13(display_short)|uniprotkb:HOX3G(gene name synonym)|uniprotkb:Homeobox protein Hox-3G(gene name synonym) psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677931|imex:IM-28774-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059106.2|ensembl:ENSG00000123364(gene)|ensembl:ENST00000243056(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:3229(identity) refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N|entrezgene/locuslink:328(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sGnVE8V9ZSPBuUnE8vdLLosrIa49606 rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606 rigid:D53yteMZbjxLXb2bqn5u94QJGrM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31276 uniprotkb:P31274 intact:EBI-2293590|uniprotkb:Q5BL02|uniprotkb:Q96J32|uniprotkb:Q9NR24|uniprotkb:Q9NYD5|ensembl:ENSP00000243056 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:hxc13_human(display_long)|uniprotkb:HOXC13(gene name)|psi-mi:HOXC13(display_short)|uniprotkb:HOX3G(gene name synonym)|uniprotkb:Homeobox protein Hox-3G(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677923|imex:IM-28774-3369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059106.2|ensembl:ENSG00000123364(gene)|ensembl:ENST00000243056(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:3229(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sGnVE8V9ZSPBuUnE8vdLLosrIa49606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:EGWZhy/tOT8o9s99Go6zvhFyc90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31276 uniprotkb:Q99729 intact:EBI-2293590|uniprotkb:Q5BL02|uniprotkb:Q96J32|uniprotkb:Q9NR24|uniprotkb:Q9NYD5|ensembl:ENSP00000243056 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:hxc13_human(display_long)|uniprotkb:HOXC13(gene name)|psi-mi:HOXC13(display_short)|uniprotkb:HOX3G(gene name synonym)|uniprotkb:Homeobox protein Hox-3G(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677915|imex:IM-28774-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059106.2|ensembl:ENSG00000123364(gene)|ensembl:ENST00000243056(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:3229(identity) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N|entrezgene/locuslink:3182(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sGnVE8V9ZSPBuUnE8vdLLosrIa49606 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:qkT9MEhD2UVzDqNAG7D7CfN8Lco false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43248 uniprotkb:P32780 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677907|imex:IM-28774-2957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N|entrezgene/locuslink:2965(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:c2RuhEoHupLVakb3MO1fIMOw5x0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31274 uniprotkb:P05423 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677899|imex:IM-28774-3367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:2RwZYRPdSTla/YvxF985PMJwQU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31274 uniprotkb:Q12926 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 intact:EBI-11285353|uniprotkb:D3DRK3|uniprotkb:Q13235|uniprotkb:Q59G15|uniprotkb:Q8NEM4|uniprotkb:Q9H1Q8|ensembl:ENSP00000369460|ensembl:ENSP00000380479|ensembl:ENSP00000440998 psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:elav2_human(display_long)|uniprotkb:ELAVL2(gene name)|psi-mi:ELAVL2(display_short)|uniprotkb:ELAV-like neuronal protein 1(gene name synonym)|uniprotkb:HUB(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)|uniprotkb:Nervous system-specific RNA-binding protein Hel-N1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677891|imex:IM-28774-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) refseq:NP_001164666.1|refseq:NP_001164668.1|refseq:NP_004423.2|ensembl:ENSG00000107105(gene)|ensembl:ENST00000380117(transcript)|ensembl:ENST00000397312(transcript)|ensembl:ENST00000544538(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034914|interpro:IPR034999|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016869908.1|refseq:XP_016869909.1|refseq:XP_016869910.1|refseq:XP_016869911.1|refseq:XP_016869912.1|refseq:XP_016869913.1|refseq:XP_016869914.1|entrezgene/locuslink:1993(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rogid:Z17PDyoxDFJbfrFlvD3xS91rtLk9606 rigid:9i45C98+kEuVgllyIBy1BCUkZgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31260 uniprotkb:P05423 intact:EBI-2293516|uniprotkb:O43370|uniprotkb:O43605|uniprotkb:Q15949|uniprotkb:Q504T1|ensembl:ENSP00000283921 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:hxa10_human(display_long)|uniprotkb:HOXA10(gene name)|psi-mi:HOXA10(display_short)|uniprotkb:HOX1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym)|uniprotkb:PL(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677883|imex:IM-28774-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061824.3|ensembl:ENSG00000253293(gene)|ensembl:ENST00000283921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:3206(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MLQBPBS4U2GIsWQyBQ/oZlwQLkY9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:aP0V4aEPI2CVbqQentbvPfqrsaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99729 uniprotkb:P05423 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677739|imex:IM-28774-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N|entrezgene/locuslink:3182(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:k+lV8Ciu6P64fepm9DQLopr9E0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99729 uniprotkb:Q12926 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 intact:EBI-11285353|uniprotkb:D3DRK3|uniprotkb:Q13235|uniprotkb:Q59G15|uniprotkb:Q8NEM4|uniprotkb:Q9H1Q8|ensembl:ENSP00000369460|ensembl:ENSP00000380479|ensembl:ENSP00000440998 psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:elav2_human(display_long)|uniprotkb:ELAVL2(gene name)|psi-mi:ELAVL2(display_short)|uniprotkb:ELAV-like neuronal protein 1(gene name synonym)|uniprotkb:HUB(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)|uniprotkb:Nervous system-specific RNA-binding protein Hel-N1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677731|imex:IM-28774-3365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N|entrezgene/locuslink:3182(identity) refseq:NP_001164666.1|refseq:NP_001164668.1|refseq:NP_004423.2|ensembl:ENSG00000107105(gene)|ensembl:ENST00000380117(transcript)|ensembl:ENST00000397312(transcript)|ensembl:ENST00000544538(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034914|interpro:IPR034999|interpro:IPR035979|reactome:R-HSA-72163|refseq:XP_016869908.1|refseq:XP_016869909.1|refseq:XP_016869910.1|refseq:XP_016869911.1|refseq:XP_016869912.1|refseq:XP_016869913.1|refseq:XP_016869914.1|entrezgene/locuslink:1993(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rogid:Z17PDyoxDFJbfrFlvD3xS91rtLk9606 rigid:+5mKWM/Aa7OT84C3IOv2NcpjI7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14541 uniprotkb:Q16534 intact:EBI-20826259|ensembl:ENSP00000346339|uniprotkb:Q7Z2V9|uniprotkb:Q9UH81|uniprotkb:Q9UIS6 intact:EBI-2798854|uniprotkb:A8K1X8|uniprotkb:Q6FHS9|ensembl:ENSP00000226067 psi-mi:hnf4g_human(display_long)|uniprotkb:HNF4G(gene name)|psi-mi:HNF4G(display_short)|uniprotkb:NR2A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym) psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677723|imex:IM-28774-1617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164749(gene)|ensembl:ENST00000354370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1LV2|reactome:R-HSA-210745|reactome:R-HSA-383280|refseq:NP_001317490.1|refseq:NP_004124.4|refseq:XP_016868862.1|refseq:XP_016868863.1|refseq:XP_016868864.1|refseq:XP_016868865.1|entrezgene/locuslink:3174(identity) refseq:NP_002117.1|refseq:NP_001317304.1|ensembl:ENSG00000108924(gene)|ensembl:ENST00000226067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029829|interpro:IPR040223|entrezgene/locuslink:3131(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XtOPPDE+7NKQK3ZPo+04FQR9nks9606 rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606 rigid:IKDXJqv6ADVuCcusGF7tCxJZDRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUU6 uniprotkb:O55144 intact:EBI-26677648 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:hnf4g_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym)|uniprotkb:Hnf4g(gene name)|psi-mi:Hnf4g(display_short)|uniprotkb:Nr2a2(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677715|imex:IM-28774-1191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|refseq:NP_038948.1|reactome:R-MMU-383280|interpro:IPR035500|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|entrezgene/locuslink:30942(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0mxaE/z0RoinzQOBOvurwnCRtE10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:FppPKfdFYJVvjVk1aOc3OVGH/Bc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUU6 uniprotkb:Q62227 intact:EBI-26677648 intact:EBI-4310440|uniprotkb:Q53Z53|ensembl:ENSMUSP00000039175 psi-mi:hnf4g_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym)|uniprotkb:Hnf4g(gene name)|psi-mi:Hnf4g(display_short)|uniprotkb:Nr2a2(gene name synonym) psi-mi:nr0b2_mouse(display_long)|uniprotkb:Nr0b2(gene name)|psi-mi:Nr0b2(display_short)|uniprotkb:Shp(gene name synonym)|uniprotkb:Orphan nuclear receptor SHP(gene name synonym)|uniprotkb:Small heterodimer partner(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677707|imex:IM-28774-2105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|refseq:NP_038948.1|reactome:R-MMU-383280|interpro:IPR035500|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|entrezgene/locuslink:30942(identity) refseq:NP_035980.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0009749"(response to glucose)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR033544|interpro:IPR035500|rcsb pdb:1YMT|rcsb pdb:4NUF|reactome:R-MMU-383280|ensembl:ENSMUSG00000037583(gene)|ensembl:ENSMUST00000042706(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007623"(circadian rhythm)|entrezgene/locuslink:23957(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0mxaE/z0RoinzQOBOvurwnCRtE10090 rogid:4xa6eksKn8BX8WuptwL29rnNB2c10090 rigid:Ko6XKynGoz6UyQrBg+v0csCm5nI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUU6 uniprotkb:P50220 intact:EBI-26677648 intact:EBI-9986706|ensembl:ENSMUSP00000001536|ensembl:ENSMUSP00000136103 psi-mi:hnf4g_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym)|uniprotkb:Hnf4g(gene name)|psi-mi:Hnf4g(display_short)|uniprotkb:Nr2a2(gene name synonym) psi-mi:nkx21_mouse(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677699|imex:IM-28774-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|refseq:NP_038948.1|reactome:R-MMU-383280|interpro:IPR035500|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|entrezgene/locuslink:30942(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0048663"(neuron fate commitment)|ensembl:ENSMUSG00000001496(gene)|ensembl:ENSMUST00000001536(transcript)|ensembl:ENSMUST00000178477(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|refseq:NP_033411.3|entrezgene/locuslink:21869(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0mxaE/z0RoinzQOBOvurwnCRtE10090 rogid:0Zwz5Ml8BYQvWD9b3yGKehXuaTw10090 rigid:MsKoq9QznjmMPy0a5v+GUTuxmNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUU6 uniprotkb:Q05BA5 intact:EBI-26677648 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:hnf4g_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym)|uniprotkb:Hnf4g(gene name)|psi-mi:Hnf4g(display_short)|uniprotkb:Nr2a2(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677691|imex:IM-28774-2953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|refseq:NP_038948.1|reactome:R-MMU-383280|interpro:IPR035500|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|entrezgene/locuslink:30942(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0mxaE/z0RoinzQOBOvurwnCRtE10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:ZcXLv1KjaViwxSiVGrjzG1q2ZNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUU6 uniprotkb:Q04742 intact:EBI-26677648 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:hnf4g_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym)|uniprotkb:Hnf4g(gene name)|psi-mi:Hnf4g(display_short)|uniprotkb:Nr2a2(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677683|imex:IM-28774-2103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|refseq:NP_038948.1|reactome:R-MMU-383280|interpro:IPR035500|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|entrezgene/locuslink:30942(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0mxaE/z0RoinzQOBOvurwnCRtE10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:mSSK8hERyZy7fe86WFjq1Uh+KCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUU6 uniprotkb:P70396 intact:EBI-26677648 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 psi-mi:hnf4g_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 2 group A member 2(gene name synonym)|uniprotkb:Hnf4g(gene name)|psi-mi:Hnf4g(display_short)|uniprotkb:Nr2a2(gene name synonym) psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677675|imex:IM-28774-2101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0072686"(mitotic spindle)|refseq:NP_038948.1|reactome:R-MMU-383280|interpro:IPR035500|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|entrezgene/locuslink:30942(identity) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c0mxaE/z0RoinzQOBOvurwnCRtE10090 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rigid:hOKs5CRxQKfieDwNgGqlBMaYBrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99M28 uniprotkb:Q9QY14 intact:EBI-8339636|uniprotkb:Q3TMJ1|intact:MINT-4124387|uniprotkb:Q922H8|ensembl:ENSMUSP00000085867|ensembl:ENSMUSP00000126345 intact:EBI-26677604|ensembl:ENSMUSP00000050445 psi-mi:rnps1_mouse(display_long)|uniprotkb:Rnps1(gene name)|psi-mi:Rnps1(display_short) psi-mi:foxe3_mouse(display_long)|uniprotkb:Foxe3(gene name)|psi-mi:Foxe3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677640|imex:IM-28774-2951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073596.1|refseq:NP_001073597.1|refseq:NP_033096.2|refseq:XP_017172851.1|ensembl:ENSMUSG00000034681(gene)|ensembl:ENSMUST00000088512(transcript)|ensembl:ENSMUST00000163717(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q99M28|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957|entrezgene/locuslink:19826(identity) ensembl:ENSMUSG00000044518(gene)|ensembl:ENSMUST00000050940(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048468"(cell development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:2001111"(positive regulation of lens epithelial cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_056573.1|entrezgene/locuslink:30923(identity) - comment:mint|function:"Part of pre- and post-splicing multiprotein mRNP complexes. Enhances the formation of the ATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 and SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner. Participates in mRNA 3'-end cleavage. Involved in RENT2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Also mediates increase of mRNA abundance and translational efficiency. Binds spliced mRNA 20-25 nt upstream of exon-exon junctions" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nANu/nh/pD/F6dYE2Sa28OegPGs10090 rogid:IPEp/88wZJBwBcPmnFjAJzkpGSU10090 rigid:244gVBeWTCVEQE1B9rUvV2+dhcE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14907 uniprotkb:P15976 intact:EBI-723259|uniprotkb:Q7LCQ4|ensembl:ENSP00000225525|uniprotkb:B2RD53|uniprotkb:D3DTJ6 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:tx1b3_human(display_long)|uniprotkb:Tax interaction protein 1(gene name synonym)|uniprotkb:Glutaminase-interacting protein 3(gene name synonym)|uniprotkb:TAX1BP3(gene name)|psi-mi:TAX1BP3(display_short)|uniprotkb:TIP1(gene name synonym)|uniprotkb:Tax-interacting protein 1(gene name synonym) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677596|imex:IM-28774-2529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191627.1|refseq:NP_055419.1|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017268(Tax1-binding protein 3)|interpro:IPR036034|rcsb pdb:2KG2|rcsb pdb:2L4S|rcsb pdb:2L4T|rcsb pdb:2VZ5|rcsb pdb:3GJ9|rcsb pdb:3SFJ|rcsb pdb:4E3B|rcsb pdb:4NNL|rcsb pdb:4NNM|reactome:R-HSA-5666185|ensembl:ENST00000225525(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000213977(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|entrezgene/locuslink:30851(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:w2/fv0XnJQZ+UDIXzJhdBZCtLr89606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:NJoNNXCcY+8LmopJkZUpAb8G8mQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14907 uniprotkb:Q14134 intact:EBI-723259|uniprotkb:Q7LCQ4|ensembl:ENSP00000225525|uniprotkb:B2RD53|uniprotkb:D3DTJ6 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 psi-mi:tx1b3_human(display_long)|uniprotkb:Tax interaction protein 1(gene name synonym)|uniprotkb:Glutaminase-interacting protein 3(gene name synonym)|uniprotkb:TAX1BP3(gene name)|psi-mi:TAX1BP3(display_short)|uniprotkb:TIP1(gene name synonym)|uniprotkb:Tax-interacting protein 1(gene name synonym) psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677588|imex:IM-28774-2527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191627.1|refseq:NP_055419.1|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017268(Tax1-binding protein 3)|interpro:IPR036034|rcsb pdb:2KG2|rcsb pdb:2L4S|rcsb pdb:2L4T|rcsb pdb:2VZ5|rcsb pdb:3GJ9|rcsb pdb:3SFJ|rcsb pdb:4E3B|rcsb pdb:4NNL|rcsb pdb:4NNM|reactome:R-HSA-5666185|ensembl:ENST00000225525(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000213977(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|entrezgene/locuslink:30851(identity) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:w2/fv0XnJQZ+UDIXzJhdBZCtLr89606 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rigid:hmoi3ZA0hf4OBoVSMaXWpRUz9b8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14907 uniprotkb:P35222 intact:EBI-723259|uniprotkb:Q7LCQ4|ensembl:ENSP00000225525|uniprotkb:B2RD53|uniprotkb:D3DTJ6 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:tx1b3_human(display_long)|uniprotkb:Tax interaction protein 1(gene name synonym)|uniprotkb:Glutaminase-interacting protein 3(gene name synonym)|uniprotkb:TAX1BP3(gene name)|psi-mi:TAX1BP3(display_short)|uniprotkb:TIP1(gene name synonym)|uniprotkb:Tax-interacting protein 1(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677580|imex:IM-28774-2949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191627.1|refseq:NP_055419.1|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017268(Tax1-binding protein 3)|interpro:IPR036034|rcsb pdb:2KG2|rcsb pdb:2L4S|rcsb pdb:2L4T|rcsb pdb:2VZ5|rcsb pdb:3GJ9|rcsb pdb:3SFJ|rcsb pdb:4E3B|rcsb pdb:4NNL|rcsb pdb:4NNM|reactome:R-HSA-5666185|ensembl:ENST00000225525(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000213977(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|entrezgene/locuslink:30851(identity) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|entrezgene/locuslink:1499(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:w2/fv0XnJQZ+UDIXzJhdBZCtLr89606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:EDI8AtqShBnEjfZDQoOoeTafjfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P0U4 uniprotkb:Q13285 intact:EBI-949911|ensembl:ENSP00000285106|uniprotkb:Q8N2W4|uniprotkb:Q96BC8|uniprotkb:Q9P2V7|uniprotkb:B2RC03 intact:EBI-874629|uniprotkb:O15196|uniprotkb:Q5T6F5|ensembl:ENSP00000362690 psi-mi:cxxc1_human(display_long)|uniprotkb:CFP1(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:CXXC1(gene name)|psi-mi:CXXC1(display_short)|uniprotkb:CGBP(gene name synonym)|uniprotkb:PCCX1(gene name synonym)|uniprotkb:PHF18(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym) psi-mi:stf1_human(display_long)|uniprotkb:Nuclear receptor subfamily 5 group A member 1(gene name synonym)|uniprotkb:Adrenal 4-binding protein(gene name synonym)|uniprotkb:Steroid hormone receptor Ad4BP(gene name synonym)|uniprotkb:Fushi tarazu factor homolog 1(gene name synonym)|uniprotkb:NR5A1(gene name)|psi-mi:NR5A1(display_short)|uniprotkb:AD4BP(gene name synonym)|uniprotkb:FTZF1(gene name synonym)|uniprotkb:SF1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677572|imex:IM-28774-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000154832(gene)|ensembl:ENST00000285106(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|reactome:R-HSA-381038|interpro:IPR022056|interpro:IPR037869|mint:Q9P0U4|rcsb pdb:3QMB|rcsb pdb:3QMC|rcsb pdb:3QMD|rcsb pdb:3QMG|rcsb pdb:3QMH|rcsb pdb:3QMI|refseq:NP_001095124.1|refseq:NP_055408.2|refseq:XP_011524242.1|refseq:XP_016881207.1|dip:DIP-50001N|entrezgene/locuslink:30827(identity) refseq:XP_005251928.1|refseq:NP_004950.2|refseq:XP_011516757.1|ensembl:ENSG00000136931(gene)|ensembl:ENST00000373588(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001553"(luteinization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0007538"(primary sex determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009888"(tissue development)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0030325"(adrenal gland development)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097210"(response to gonadotropin-releasing hormone)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2000195"(negative regulation of female gonad development)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|rcsb pdb:1YOW|rcsb pdb:1ZDT|rcsb pdb:4QJR|rcsb pdb:4QK4|rcsb pdb:7KHT|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-452723|reactome:R-HSA-9690406|entrezgene/locuslink:2516(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nWwPX7OlafdCMD8Qg+hETjNkKgY9606 rogid:UC4bXFO03I1iftAyX5/CJAXeTUo9606 rigid:AxapzmgUskCT28VeWi6bcRhJIdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2W7 uniprotkb:Q15633 intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677564|imex:IM-28774-1615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894|entrezgene/locuslink:30818(identity) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:jxal+gTkTmmcBvc/Ig/F9PRTDfw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57073 uniprotkb:O43248 intact:EBI-3918657|ensembl:ENSP00000293894|uniprotkb:Q9NZW2 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:sox8_human(display_long)|uniprotkb:SOX8(gene name)|psi-mi:SOX8(display_short) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677556|imex:IM-28774-2947 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005513(gene)|ensembl:ENST00000293894(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0014032"(neural crest cell development)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060221"(retinal rod cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR031265|interpro:IPR036910|go:"GO:0090184"(positive regulation of kidney development)|refseq:NP_055402.2|entrezgene/locuslink:30812(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:M9dVEArakkZgL3PX5PlAPK3E4LE9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:vGJX0NUVQL9Zm7G9g4Tb9Gg7bNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70271 uniprotkb:P15806 intact:EBI-7288319|intact:MINT-4106929|uniprotkb:Q5SWV2|uniprotkb:Q8K0W4|ensembl:ENSMUSP00000018755 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:pdli4_mouse(display_long)|uniprotkb:Pdlim4(gene name)|psi-mi:Pdlim4(display_short)|uniprotkb:Ril(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677548|imex:IM-28774-2525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062290.2|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0043197"(dendritic spine)|ensembl:ENSMUSG00000020388(gene)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|mint:P70271|ensembl:ENSMUST00000018755(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|entrezgene/locuslink:30794(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0p7CYiGd3Vpz5qQL07CNcRse+NQ10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:u9tKuo+DCmtmZBxtFxroMS2e8sc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70271 uniprotkb:Q07279 intact:EBI-7288319|intact:MINT-4106929|uniprotkb:Q5SWV2|uniprotkb:Q8K0W4|ensembl:ENSMUSP00000018755 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:pdli4_mouse(display_long)|uniprotkb:Pdlim4(gene name)|psi-mi:Pdlim4(display_short)|uniprotkb:Ril(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677540|imex:IM-28774-1189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062290.2|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0043197"(dendritic spine)|ensembl:ENSMUSG00000020388(gene)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|mint:P70271|ensembl:ENSMUST00000018755(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|entrezgene/locuslink:30794(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0p7CYiGd3Vpz5qQL07CNcRse+NQ10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:RCr0h6nh+tCSIqjYB0zKHdOnprE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTP3 uniprotkb:Q04742 intact:EBI-26677498|ensembl:ENSMUSP00000025054|ensembl:ENSMUSP00000127056 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:spdef_mouse(display_long)|uniprotkb:Prostate epithelium-specific Ets transcription factor(gene name synonym)|uniprotkb:Prostate-derived Ets factor(gene name synonym)|uniprotkb:Spdef(gene name)|psi-mi:Spdef(display_short)|uniprotkb:Pdef(gene name synonym)|uniprotkb:Pse(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677532|imex:IM-28774-2523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024215(gene)|ensembl:ENSMUST00000025054(transcript)|ensembl:ENSMUST00000167489(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010455"(positive regulation of cell fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|refseq:NP_038919.1|refseq:XP_006524442.1|refseq:XP_006524443.1|refseq:XP_006524444.1|refseq:XP_017172988.1|entrezgene/locuslink:30051(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JhEc98WNiB5CrjgNj/jROU/ajRU10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:x6E/pP5e1TrBBN4sgbiXpPdrcx4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:G3X904 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677490|imex:IM-28774-1613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:BoLetpsoFEFQMx/MWO0m60SCLWY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P02340 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-474016|uniprotkb:Q9QUP3|ensembl:ENSMUSP00000104298 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:p53_mouse(display_long)|uniprotkb:Tp53(gene name)|psi-mi:Tp53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Trp53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677482|imex:IM-28774-2521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) ensembl:ENSMUSG00000059552(gene)|ensembl:ENSMUST00000108658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|mint:P02340|rcsb pdb:1HU8|rcsb pdb:2GEQ|rcsb pdb:2IOI|rcsb pdb:2IOM|rcsb pdb:2IOO|rcsb pdb:2P52|rcsb pdb:3EXJ|rcsb pdb:3EXL|reactome:R-MMU-2559580|reactome:R-MMU-2559584|reactome:R-MMU-2559585|reactome:R-MMU-2559586|reactome:R-MMU-349425|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-5693565|reactome:R-MMU-6804754|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804758|reactome:R-MMU-6804759|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-69473|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-69895|reactome:R-MMU-8852276|reactome:R-MMU-8941855|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007569"(cell aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009411"(response to UV)|go:"GO:0009651"(response to salt stress)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010038"(response to metal ion)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033552"(response to vitamin B3)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043200"(response to amino acid)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045471"(response to ethanol)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051276"(chromosome organization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0034644"(cellular response to UV)|refseq:NP_001120705.1|refseq:NP_035770.2|refseq:XP_006533220.1|dip:DIP-369N|entrezgene/locuslink:22059(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:ZU1071LBVm95uqzi6RBNluw8wFo10090 rigid:mIYq1DBpVY7pYAbpmqlc506ZYB4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P15806 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677474|imex:IM-28774-2519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:iNquVTua50RcSXhEejLtEsRBHNM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:Q07279 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677466|imex:IM-28774-2945 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:9UBZFmzX6UKeqp9Nv9UNMX9eYwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P06876 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-366934|uniprotkb:Q61929|uniprotkb:E9QMG8|ensembl:ENSMUSP00000020158 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:myb_mouse(display_long)|uniprotkb:Myb(gene name)|psi-mi:Myb(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677458|imex:IM-28774-2099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) refseq:NP_001185843.1|refseq:NP_034978.3|rcsb pdb:1MBE|rcsb pdb:1MBF|rcsb pdb:1MBG|rcsb pdb:1MBH|rcsb pdb:1MBJ|rcsb pdb:1MBK|rcsb pdb:1MSE|rcsb pdb:1MSF|rcsb pdb:1SB0|rcsb pdb:2AGH|rcsb pdb:6DMX|rcsb pdb:6DNQ|rcsb pdb:1IDZ|ensembl:ENSMUSG00000019982(gene)|ensembl:ENSMUST00000020158(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|rcsb pdb:1GUU|rcsb pdb:1GV2|rcsb pdb:1GV5|rcsb pdb:1GVD|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1IDY|dip:DIP-31713N|entrezgene/locuslink:17863(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:BHCfLLes3QMOQXPc0SgbXNPldhw10090 rigid:0fejfmCJWK1JKsgWmaTa/UGujjA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P28357 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-26671369|ensembl:ENSMUSP00000058490|uniprotkb:A2ASM9|uniprotkb:Q3UMQ3|uniprotkb:Q3UYS2 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:hxd9_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.4(gene name synonym)|uniprotkb:Homeobox protein Hox-5.2(gene name synonym)|uniprotkb:Hoxd9(gene name)|psi-mi:Hoxd9(display_short)|uniprotkb:Hox-4.4(gene name synonym)|uniprotkb:Hoxd-9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677450|imex:IM-28774-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) ensembl:ENSMUSG00000043342(gene)|ensembl:ENSMUST00000059272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_038583.1|entrezgene/locuslink:15438(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:yAO/qVdMO1kp4tqqEXeQlloLpOU10090 rigid:fvg3vhoKygkebqNSBcIVKhbmLMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P23812 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677442|imex:IM-28774-2943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:Dj2FX4vY4HExsoRHaRGyKSV2Bqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P28359 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-445929|uniprotkb:Q91WU9|ensembl:ENSMUSP00000062412 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:hxd10_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.5(gene name synonym)|uniprotkb:Hoxd10(gene name)|psi-mi:Hoxd10(display_short)|uniprotkb:Hox-4.5(gene name synonym)|uniprotkb:Hoxd-10(gene name synonym)|uniprotkb:Homeobox protein Hox-5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677434|imex:IM-28774-1187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) refseq:NP_038582.2|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050905"(neuromuscular process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000050368(gene)|ensembl:ENSMUST00000061745(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:15430(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:N3cD2IcsB+0/7fer4wg5hZBLuew10090 rigid:2ooQDReMh5leUdX7si1fJnt1FqQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P31245 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677426|imex:IM-28774-2517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:zJpULvrErUVSORT0zhOQn81omPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P31311 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-445941|uniprotkb:Q3V026|ensembl:ENSMUSP00000040920 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:hxa11_mouse(display_long)|uniprotkb:Hoxa11(gene name)|psi-mi:Hoxa11(display_short)|uniprotkb:Hox-1.9(gene name synonym)|uniprotkb:Hoxa-11(gene name synonym)|uniprotkb:Homeobox protein Hox-1.9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677418|imex:IM-28774-3363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) refseq:NP_034580.1|ensembl:ENSMUSG00000038210(gene)|ensembl:ENSMUST00000048026(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010720"(positive regulation of cell development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048589"(developmental growth)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060065"(uterus development)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:15396(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:xmuaYwHq6mzn6Qbx/zJIcMkoNsk10090 rigid:6fxjkwosqPcHwJ5SSqIBfxy/IUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:P97489 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-26673507|ensembl:ENSMUSP00000015771|uniprotkb:Q3UQR0 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:gata5_mouse(display_long)|uniprotkb:GATA-binding factor 5(gene name synonym)|uniprotkb:Gata5(gene name)|psi-mi:Gata5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677410|imex:IM-28774-2941 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) ensembl:ENSMUSG00000015627(gene)|ensembl:ENSMUST00000015771(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003274"(endocardial cushion fusion)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0062000"(positive regulation of cardiac endothelial to mesenchymal transition)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|reactome:R-MMU-983231|refseq:NP_032119.2|refseq:XP_006500617.1|entrezgene/locuslink:14464(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:7Q0sDjuro6dsfi8e2XYl3jVIsFc10090 rigid:fwvf99VpDp6k6E4SBJHX0j4fDvs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z2U2 uniprotkb:Q61545 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677402|imex:IM-28774-1611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:abWJWV9HSj48gbuDJd3AqzzyA9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BLR9 uniprotkb:Q8VIM5 intact:EBI-26677747|ensembl:ENSMUSP00000035326|uniprotkb:A1L3B7|uniprotkb:Q3U3G4 intact:EBI-16354401|ensembl:ENSMUSP00000099695|uniprotkb:Q5SS65|uniprotkb:Q6W8X1|uniprotkb:Q8C3W6|uniprotkb:Q8VIL4 psi-mi:hif1n_mouse(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Hif1an(gene name)|psi-mi:Hif1an(display_short) psi-mi:mycd_mouse(display_long)|uniprotkb:Myocd(gene name)|psi-mi:Myocd(display_short)|uniprotkb:Basic SAP coiled-coil transcription activator 2(gene name synonym)|uniprotkb:Bsac2(gene name synonym)|uniprotkb:Mycd(gene name synonym)|uniprotkb:SRF cofactor protein(gene name synonym)|uniprotkb:Srfcp(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677793|imex:IM-28774-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036450(gene)|ensembl:ENSMUST00000040455(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|reactome:R-MMU-1234174|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|refseq:NP_795932.2|entrezgene/locuslink:319594(identity) ensembl:ENSMUSG00000020542(gene)|ensembl:ENSMUST00000102635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003257"(positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0000785"(chromatin)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043954"(cellular component maintenance)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048565"(digestive tract development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060065"(uterus development)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070514"(SRF-myogenin-E12 complex)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900239"(regulation of phenotypic switching)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000721"(positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|go:"GO:2000724"(positive regulation of cardiac vascular smooth muscle cell differentiation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004018(RPEL repeat)|interpro:IPR028721|interpro:IPR036361|interpro:IPR043451|dip:DIP-29754N|refseq:NP_660118.3|refseq:NP_666498.2|refseq:XP_011247197.1|entrezgene/locuslink:214384(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:KeIzXsW0VKPpWc2sdX+Q5qyYLZI10090 rogid:0drX57b4fxsVTIBKI/U/WwTGFU410090 rigid:x3bKA9AARsOulXcQfakT2P40ZX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CWU2 uniprotkb:Q6PDK0 intact:EBI-8430035|intact:MINT-4140521|uniprotkb:Q3UKV1|uniprotkb:Q3UK32|ensembl:ENSMUSP00000112498 intact:EBI-26677801|ensembl:ENSMUSP00000052717 psi-mi:zdh13_mouse(display_long)|uniprotkb:Zdhhc13(gene name)|psi-mi:Zdhhc13(display_short)|uniprotkb:Hip14l(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 13(gene name synonym)|uniprotkb:Huntingtin-interacting protein 14-related protein(gene name synonym) psi-mi:q6pdk0_mouse(display_long)|uniprotkb:Zbtb39(gene name)|psi-mi:Zbtb39(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677817|imex:IM-28774-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082307.1|ensembl:ENSMUSG00000030471(gene)|ensembl:ENSMUST00000118927(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030660"(Golgi-associated vesicle membrane)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030290|interpro:IPR036770|mint:Q9CWU2|entrezgene/locuslink:243983(identity) ensembl:ENSMUSG00000044617(gene)|ensembl:ENSMUST00000054287(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_932152.1|entrezgene/locuslink:320080(identity) - function:May be involved in the NF-kappa-B signaling pathway|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JOcxB1KD8I67o1rhpbrbENZDWrA10090 rogid:DEpgnLrbRIETS/HEsTRuYmknTcY10090 rigid:PD+EIyWGqK8VYzFyN9FQQiJpuv4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDK0 uniprotkb:Q9CZT4 intact:EBI-26677801|ensembl:ENSMUSP00000052717 intact:EBI-26677825|ensembl:ENSMUSP00000033173|ensembl:ENSMUSP00000102092|uniprotkb:Q8CI35|uniprotkb:Q9DBD1 psi-mi:q6pdk0_mouse(display_long)|uniprotkb:Zbtb39(gene name)|psi-mi:Zbtb39(display_short) psi-mi:rpc5_mouse(display_long)|uniprotkb:Sex-lethal interactor homolog(gene name synonym)|uniprotkb:Polr3e(gene name)|psi-mi:Polr3e(display_short)|uniprotkb:Sin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677851|imex:IM-28774-1619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000044617(gene)|ensembl:ENSMUST00000054287(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_932152.1|entrezgene/locuslink:320080(identity) ensembl:ENSMUSG00000030880(gene)|ensembl:ENSMUST00000033173(transcript)|ensembl:ENSMUST00000106483(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR006886(Sin-like protein conserved region)|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|refseq:NP_001157568.1|refseq:NP_079574.2|entrezgene/locuslink:26939(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DEpgnLrbRIETS/HEsTRuYmknTcY10090 rogid:0JD6k+Kwr+i6mwVzjlATHbG2HM810090 rigid:UEEF4c0uzhCtbsU/qjqRj+Lx8kw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PDK0 uniprotkb:Q8VHS6 intact:EBI-26677801|ensembl:ENSMUSP00000052717 intact:EBI-26675998|ensembl:ENSMUSP00000031696|ensembl:ENSMUSP00000112965|uniprotkb:Q8CDP8 psi-mi:q6pdk0_mouse(display_long)|uniprotkb:Zbtb39(gene name)|psi-mi:Zbtb39(display_short) psi-mi:asb15_mouse(display_long)|uniprotkb:Asb15(gene name)|psi-mi:Asb15(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677859|imex:IM-28774-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000044617(gene)|ensembl:ENSMUST00000054287(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_932152.1|entrezgene/locuslink:320080(identity) ensembl:ENSMUSG00000029685(gene)|ensembl:ENSMUST00000031696(transcript)|ensembl:ENSMUST00000117688(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|refseq:NP_543123.2|refseq:XP_011239391.1|entrezgene/locuslink:78910(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DEpgnLrbRIETS/HEsTRuYmknTcY10090 rogid:k90YXTebsFC0kF2V8wAQe54DFVM10090 rigid:2G4mIVR0lvkCoAFnTCYy6TTlyT4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31260 uniprotkb:Q04741 intact:EBI-2293516|uniprotkb:O43370|uniprotkb:O43605|uniprotkb:Q15949|uniprotkb:Q504T1|ensembl:ENSP00000283921 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 psi-mi:hxa10_human(display_long)|uniprotkb:HOXA10(gene name)|psi-mi:HOXA10(display_short)|uniprotkb:HOX1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym)|uniprotkb:PL(gene name synonym) psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677875|imex:IM-28774-2107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061824.3|ensembl:ENSG00000253293(gene)|ensembl:ENST00000283921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:3206(identity) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:MLQBPBS4U2GIsWQyBQ/oZlwQLkY9606 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rigid:wEp+x7DBWHDq6qZqOpI3UdhU5NY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20719 uniprotkb:P35638 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677867|imex:IM-28774-2955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719|entrezgene/locuslink:3202(identity) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' crc64:31905293FB1FBBE2 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:N8c8qqn2/amX4e53dUQrHzeXe2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P9Y7 uniprotkb:P18111 intact:EBI-26678127|ensembl:ENSMUSP00000079647|uniprotkb:Q6ZPG0|uniprotkb:Q8BIP1 intact:EBI-21005290|ensembl:ENSMUSP00000025521|uniprotkb:Q8VCF7 psi-mi:zfp82_mouse(display_long)|uniprotkb:Zinc finger protein 545(gene name synonym)|uniprotkb:Zfp82(gene name)|psi-mi:Zfp82(display_short)|uniprotkb:Kiaa1948(gene name synonym)|uniprotkb:Znf545(gene name synonym) psi-mi:cdx1_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 1(gene name synonym)|uniprotkb:Cdx1(gene name)|psi-mi:Cdx1(display_short)|uniprotkb:Cdx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678152|imex:IM-28774-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000098022(gene)|ensembl:ENSMUST00000080834(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001239448.1|refseq:NP_001240314.1|refseq:NP_808557.2|entrezgene/locuslink:330502(identity) go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060349"(bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000024619(gene)|ensembl:ENSMUST00000025521(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|refseq:NP_034010.3|entrezgene/locuslink:12590(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:18VHXGq8oTYfRSmmG1ELO7PewYU10090 rogid:Rzc2qIxNozTifZX/rvuUx8uc6lU10090 rigid:odKg09e8Y+qzB6YwLnjWFdNQvSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P9Y7 uniprotkb:Q61545 intact:EBI-26678127|ensembl:ENSMUSP00000079647|uniprotkb:Q6ZPG0|uniprotkb:Q8BIP1 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zfp82_mouse(display_long)|uniprotkb:Zinc finger protein 545(gene name synonym)|uniprotkb:Zfp82(gene name)|psi-mi:Zfp82(display_short)|uniprotkb:Kiaa1948(gene name synonym)|uniprotkb:Znf545(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678160|imex:IM-28774-1621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000098022(gene)|ensembl:ENSMUST00000080834(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001239448.1|refseq:NP_001240314.1|refseq:NP_808557.2|entrezgene/locuslink:330502(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:18VHXGq8oTYfRSmmG1ELO7PewYU10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:JQ0RDQgTCOuAphuDPKWY0fl6BmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BKT3 uniprotkb:Q05BA5 intact:EBI-26678080|ensembl:ENSMUSP00000035644|uniprotkb:Q3UWF7|uniprotkb:Q8BK44 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:gcfc2_mouse(display_long)|uniprotkb:GC-rich sequence DNA-binding factor(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor 2(gene name synonym)|uniprotkb:Transcription factor 9(gene name synonym)|uniprotkb:Gcfc2(gene name)|psi-mi:Gcfc2(display_short)|uniprotkb:Gcf(gene name synonym)|uniprotkb:Tcf9(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678111|imex:IM-28774-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035125(gene)|ensembl:ENSMUST00000043195(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR012890(GC-rich sequence DNA-binding factor-like)|interpro:IPR022783|reactome:R-MMU-72163|refseq:NP_808552.2|entrezgene/locuslink:330361(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:evSIibclK45gQT6ARuARyWJeBcg10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:yYXJLx9FTtrR2W3Tkwfar5ZL02E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BKT3 uniprotkb:P48972 intact:EBI-26678080|ensembl:ENSMUSP00000035644|uniprotkb:Q3UWF7|uniprotkb:Q8BK44 intact:EBI-5738119|ensembl:ENSMUSP00000018005 psi-mi:gcfc2_mouse(display_long)|uniprotkb:GC-rich sequence DNA-binding factor(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor 2(gene name synonym)|uniprotkb:Transcription factor 9(gene name synonym)|uniprotkb:Gcfc2(gene name)|psi-mi:Gcfc2(display_short)|uniprotkb:Gcf(gene name synonym)|uniprotkb:Tcf9(gene name synonym) psi-mi:mybb_mouse(display_long)|uniprotkb:Mybl2(gene name)|psi-mi:Mybl2(display_short)|uniprotkb:Bmyb(gene name synonym)|uniprotkb:Myb-like protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678103|imex:IM-28774-2113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035125(gene)|ensembl:ENSMUST00000043195(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR012890(GC-rich sequence DNA-binding factor-like)|interpro:IPR022783|reactome:R-MMU-72163|refseq:NP_808552.2|entrezgene/locuslink:330361(identity) refseq:NP_032678.1|ensembl:ENSMUSG00000017861(gene)|ensembl:ENSMUST00000018005(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|rcsb pdb:2D9A|entrezgene/locuslink:17865(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:evSIibclK45gQT6ARuARyWJeBcg10090 rogid:2R9Q8v7s40AR3teOYrd7/+/2GaQ10090 rigid:IaHzQgcv0+Yk4Mpei+w42FIwPZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UAV3 uniprotkb:Q923E4 intact:EBI-26678010 intact:EBI-1802585|uniprotkb:Q9QXG8|ensembl:ENSMUSP00000020257|ensembl:ENSMUSP00000112595 psi-mi:q3uav3_mouse(display_long)|uniprotkb:Zfp236(gene name)|psi-mi:Zfp236(display_short) psi-mi:sir1_mouse(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Sir2l1(gene name synonym)|uniprotkb:SIR2alpha(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678072|imex:IM-28774-1197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_808500.2|entrezgene/locuslink:329002(identity) refseq:NP_062786.1|dip:DIP-47052N|ensembl:ENSMUSG00000020063(gene)|ensembl:ENSMUST00000020257(transcript)|ensembl:ENSMUST00000120239(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014858"(positive regulation of skeletal muscle cell proliferation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044321"(response to leptin)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0006325"(chromatin organization)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000614"(positive regulation of thyroid-stimulating hormone secretion)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-MMU-3371453|reactome:R-MMU-427359|reactome:R-MMU-9617629|entrezgene/locuslink:93759(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HpEtxArItIy430ITUrfwJ31/H2A10090 rogid:oMEdQHMy6vybdgCwbHeo3au9YHc10090 rigid:X/46MH0Qu3btyPVzxz/ymbwy8T8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UAV3 uniprotkb:V9GX74 intact:EBI-26678010 intact:EBI-26678042|ensembl:ENSMUSP00000139017 psi-mi:q3uav3_mouse(display_long)|uniprotkb:Zfp236(gene name)|psi-mi:Zfp236(display_short) psi-mi:v9gx74_mouse(display_long)|uniprotkb:Trps1(gene name)|psi-mi:Trps1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678064|imex:IM-28774-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_808500.2|entrezgene/locuslink:329002(identity) ensembl:ENSMUSG00000038679(gene)|ensembl:ENSMUST00000183757(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028440|interpro:IPR036236|refseq:NP_001297410.1|entrezgene/locuslink:83925(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HpEtxArItIy430ITUrfwJ31/H2A10090 rogid:Q9XRWPP7QOn3QLX9iIQaJc4uejE10090 rigid:ufj778Jy41hx53eVguo3YP7w8B4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q3UAV3 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26678010 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:q3uav3_mouse(display_long)|uniprotkb:Zfp236(gene name)|psi-mi:Zfp236(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678034|imex:IM-28774-3373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_808500.2|entrezgene/locuslink:329002(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:HpEtxArItIy430ITUrfwJ31/H2A10090 rigid:WmnSFrK0fGz/kPEM4uQQZb+QtpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UAV3 uniprotkb:Q9JI90 intact:EBI-26678010 intact:EBI-6841039|uniprotkb:Q7TPR0|uniprotkb:Q9D0L2|uniprotkb:Q9D6N2|uniprotkb:Q9D6Z8|uniprotkb:Q9JI89|ensembl:ENSMUSP00000072212|ensembl:ENSMUSP00000126205|ensembl:ENSMUSP00000157833 psi-mi:q3uav3_mouse(display_long)|uniprotkb:Zfp236(gene name)|psi-mi:Zfp236(display_short) psi-mi:rnf14_mouse(display_long)|uniprotkb:Rnf14(gene name)|psi-mi:Rnf14(display_short)|uniprotkb:Ara54(gene name synonym)|uniprotkb:Triad2(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Protein Triad2(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678026|imex:IM-28774-1195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_808500.2|entrezgene/locuslink:329002(identity) refseq:NP_001158093.1|refseq:NP_001158094.1|refseq:NP_064396.2|refseq:XP_017173444.1|refseq:XP_017173445.1|refseq:XP_017173446.1|ensembl:ENSMUSG00000060450(gene)|ensembl:ENSMUST00000072376(transcript)|ensembl:ENSMUST00000171461(transcript)|ensembl:ENSMUST00000236116(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|reactome:R-MMU-983168|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_006526184.1|refseq:XP_006526185.1|refseq:XP_006526186.1|refseq:XP_006526187.1|refseq:XP_006526188.1|refseq:XP_006526189.1|refseq:XP_006526190.1|entrezgene/locuslink:56736(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HpEtxArItIy430ITUrfwJ31/H2A10090 rogid:Zwq8Ma519wCUdK60xVxmfxGGZvo10090 rigid:3cstKS4Kpp+R5pbDFJMo0YEccWY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UAV3 uniprotkb:Q6P3E7 intact:EBI-26678010 intact:EBI-11707298|uniprotkb:G3X9I8|ensembl:ENSMUSP00000080832 psi-mi:q3uav3_mouse(display_long)|uniprotkb:Zfp236(gene name)|psi-mi:Zfp236(display_short) psi-mi:hda10_mouse(display_long)|uniprotkb:Histone deacetylase 10(gene name synonym)|uniprotkb:Hdac10(gene name)|psi-mi:Hdac10(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678018|imex:IM-28774-3371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_808500.2|entrezgene/locuslink:329002(identity) refseq:NP_954668.2|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047609"(acetylputrescine deacetylase activity)|go:"GO:0047611"(acetylspermidine deacetylase activity)|go:"GO:0106047"(polyamine deacetylation)|go:"GO:0106048"(spermidine deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|ensembl:ENSMUSG00000062906(gene)|ensembl:ENSMUST00000082197(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035825"(homologous recombination)|entrezgene/locuslink:170787(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HpEtxArItIy430ITUrfwJ31/H2A10090 rogid:DahoUwe9Em+xnUFMmwG8mLiA4UY10090 rigid:FUgi6zx62SLwoVoAO4mbSyEHUn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B2RWS6 uniprotkb:Q9WVB3 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 intact:EBI-2905816|ensembl:ENSMUSP00000071905 psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:tle6_mouse(display_long)|uniprotkb:Tle6(gene name)|psi-mi:Tle6(display_short)|uniprotkb:Grg6(gene name synonym)|uniprotkb:Groucho-related protein 6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678002|imex:IM-28774-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N|entrezgene/locuslink:328572(identity) ensembl:ENSMUSG00000034758(gene)|ensembl:ENSMUST00000072020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106333"(subcortical maternal complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0051293"(establishment of spindle localization)|refseq:NP_444484.1|entrezgene/locuslink:114606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 rogid:SbouSZ4/pQUM5+MgUBYZdwANjI010090 rigid:xEcEmY1TZU6O8q9Pf8OIC9D9bDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28356 uniprotkb:P31274 intact:EBI-3908736|uniprotkb:Q86ST1|ensembl:ENSP00000249499 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:hxd9_human(display_long)|uniprotkb:HOXD9(gene name)|psi-mi:HOXD9(display_short)|uniprotkb:HOX4C(gene name synonym)|uniprotkb:Homeobox protein Hox-4C(gene name synonym)|uniprotkb:Homeobox protein Hox-5.2(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677994|imex:IM-28774-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055028.3|ensembl:ENSG00000128709(gene)|ensembl:ENST00000249499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:3235(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UF3kiWYuTF7+5KyF+u+RuUNSGrY9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:bmayhTWv2wcZCHSK+iYPDwO3IF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09016 uniprotkb:Q99729 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677986|imex:IM-28774-2531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N|entrezgene/locuslink:3182(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:rq8GTOHHPJIi0KlGddwF4GoTzjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43268 uniprotkb:P09016 intact:EBI-6447147|ensembl:ENSP00000321835|ensembl:ENSP00000377273|ensembl:ENSP00000465718|uniprotkb:B7Z5J3|uniprotkb:B7Z9J6|uniprotkb:Q96AW9|uniprotkb:A8K314 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:etv4_human(display_long)|uniprotkb:Adenovirus E1A enhancer-binding protein(gene name synonym)|uniprotkb:E1A-F(gene name synonym)|uniprotkb:E1AF(gene name synonym)|uniprotkb:PEA3(gene name synonym)|uniprotkb:Polyomavirus enhancer activator 3 homolog(gene name synonym)|uniprotkb:ETV4(gene name)|psi-mi:ETV4(display_short) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677978|imex:IM-28774-2111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175832(gene)|ensembl:ENST00000319349(transcript)|ensembl:ENST00000393664(transcript)|ensembl:ENST00000591713(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR006715(PEA3-type ETS-domain transcription factor, N-terminal)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:4UUV|rcsb pdb:5ILU|reactome:R-HSA-5687128|rcsb pdb:4CO8|refseq:NP_001073143.1|refseq:NP_001248366.1|refseq:NP_001248367.1|refseq:NP_001977.1|refseq:NP_001248368.1|dip:DIP-748N|entrezgene/locuslink:2118(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9CuoBGjLzbo93LSm5yNFuBQlATg9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:rVxpV0LKgLj2jTs3o+LSbTvqI/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZZ0 uniprotkb:P31274 intact:EBI-26677939|ensembl:ENSP00000328598|uniprotkb:B2RAB4 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:hxd1_human(display_long)|uniprotkb:Homeobox protein Hox-GG(gene name synonym)|uniprotkb:HOXD1(gene name)|psi-mi:HOXD1(display_short)|uniprotkb:HOX4(gene name synonym)|uniprotkb:HOX4G(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677962|imex:IM-28774-1193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128645(gene)|ensembl:ENST00000331462(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030182"(neuron differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_078777.1|entrezgene/locuslink:3231(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DGNZU8S/LXiocM8AJYUqEo/fNPA9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:9FF1OJQDNX/smXBsOQee56rQd5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31249 uniprotkb:Q16531 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26677970|imex:IM-28774-2109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1|entrezgene/locuslink:3232(identity) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N|entrezgene/locuslink:1642(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:XgkTxlLUg+BMz115kdKFOunJ1kk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:P35548 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678360|imex:IM-28774-1625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rigid:gFu1ezt5FK5SwfR5CDe7aFQS6GY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00470 uniprotkb:O43248 intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678352|imex:IM-28774-2963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002389.1|ensembl:ENSG00000143995(gene)|ensembl:ENST00000272369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|entrezgene/locuslink:4211(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:XhTIL0eMns0k9Um0L6bn4ME8mds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00470 uniprotkb:O43763 intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678344|imex:IM-28774-717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002389.1|ensembl:ENSG00000143995(gene)|ensembl:ENST00000272369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|entrezgene/locuslink:4211(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:PiKnLN3BWGeDNaDnPP7SpF9Eljg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00470 uniprotkb:Q04743 intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369 intact:EBI-399831|uniprotkb:Q96NN8|uniprotkb:Q9BQF4|uniprotkb:G3V305|ensembl:ENSP00000450962 psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short) psi-mi:emx2_human(display_long)|uniprotkb:EMX2(gene name)|psi-mi:EMX2(display_short)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678336|imex:IM-28774-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002389.1|ensembl:ENSG00000143995(gene)|ensembl:ENST00000272369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|entrezgene/locuslink:4211(identity) refseq:NP_001159396.1|refseq:NP_004089.1|ensembl:ENSG00000170370(gene)|ensembl:ENST00000553456(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:2018(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606 rogid:+b7ChE+6RlzUb0sr/8vnDFtFy2c9606 rigid:syIaGITvxH51TvqcOlQFb+ztFA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14566 uniprotkb:P49736 intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678328|imex:IM-28774-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N|entrezgene/locuslink:4175(identity) ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N|entrezgene/locuslink:4171(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:4hXE2+Qq2jFc14HnFk5gj+bbE3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14566 uniprotkb:P49736 intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678320|imex:IM-28774-2537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N|entrezgene/locuslink:4175(identity) ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N|entrezgene/locuslink:4171(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:4hXE2+Qq2jFc14HnFk5gj+bbE3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33991 uniprotkb:O43763 intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678312|imex:IM-28774-715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N|entrezgene/locuslink:4173(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:zrLaOU5pT42ZkopOQN6P35X6xak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13485 uniprotkb:P84022 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678304|imex:IM-28774-713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N|entrezgene/locuslink:4089(identity) refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|entrezgene/locuslink:4088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mPu190hmySGV54KAtldys/IHuo89606 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:gR3xT2sBLLIJA6tu7FJXNwDQOu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13485 uniprotkb:P84022 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678296|imex:IM-28774-1205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N|entrezgene/locuslink:4089(identity) refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|entrezgene/locuslink:4088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mPu190hmySGV54KAtldys/IHuo89606 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:gR3xT2sBLLIJA6tu7FJXNwDQOu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13485 uniprotkb:Q15796 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678288|imex:IM-28774-2535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N|entrezgene/locuslink:4089(identity) refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N|entrezgene/locuslink:4087(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mPu190hmySGV54KAtldys/IHuo89606 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:1nZLsDUQ5cci2Xkb9Go0hvi1YAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13485 uniprotkb:P23769 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678280|imex:IM-28774-711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N|entrezgene/locuslink:4089(identity) refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|entrezgene/locuslink:2624(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mPu190hmySGV54KAtldys/IHuo89606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 rigid:3pHAGk6pMHVRa25Httc5nyegQ6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P84022 uniprotkb:O43248 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678272|imex:IM-28774-1203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|entrezgene/locuslink:4088(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:OfK41pW4AokYO9ksf4s0hsMhU7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P84022 uniprotkb:Q01543 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 intact:EBI-2271018|uniprotkb:B4DFV4|uniprotkb:Q14319|uniprotkb:Q92480|uniprotkb:Q9UE07|uniprotkb:B2R8H2|uniprotkb:B4DTC6|uniprotkb:G3V183|ensembl:ENSP00000433488 psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:fli1_human(display_long)|uniprotkb:FLI1(gene name)|psi-mi:FLI1(display_short)|uniprotkb:Proto-oncogene Fli-1(gene name synonym)|uniprotkb:Transcription factor ERGB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678264|imex:IM-28774-1623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|entrezgene/locuslink:4088(identity) refseq:NP_002008.2|refseq:NP_001161153.1|refseq:NP_001257939.1|refseq:NP_001257941.1|go:"GO:0030154"(cell differentiation)|go:"GO:0035855"(megakaryocyte development)|ensembl:ENSG00000151702(gene)|ensembl:ENST00000527786(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007599"(hemostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016604"(nuclear body)|refseq:XP_011541003.1|refseq:XP_016872894.1|refseq:XP_016872895.1|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035573|interpro:IPR035575|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1FLI|rcsb pdb:1X66|rcsb pdb:2YTU|rcsb pdb:5E8G|rcsb pdb:5E8I|rcsb pdb:5JVT|rcsb pdb:6VG2|rcsb pdb:6VG8|rcsb pdb:6VGD|reactome:R-HSA-9616222|entrezgene/locuslink:2313(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rogid:WCQw202NBbJxHliWsFCoYNv45WM9606 rigid:RfCYWlWP9Df3mX3Hn981T8fTNf8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20719 uniprotkb:Q15797 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 intact:EBI-1567153|uniprotkb:Q16636|uniprotkb:D3DNZ9|uniprotkb:A8KAJ0|uniprotkb:Q9UFT8|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568 psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:smad1_human(display_long)|uniprotkb:Mad-related protein 1(gene name synonym)|uniprotkb:SMAD family member 1(gene name synonym)|uniprotkb:Transforming growth factor-beta-signaling protein 1(gene name synonym)|uniprotkb:JV4-1(gene name synonym)|uniprotkb:SMAD1(gene name)|psi-mi:SMAD1(display_short)|uniprotkb:BSP1(gene name synonym)|uniprotkb:MADH1(gene name synonym)|uniprotkb:MADR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678256|imex:IM-28774-709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719|entrezgene/locuslink:3202(identity) refseq:XP_006714280.1|refseq:NP_001003688.1|refseq:NP_005891.1|refseq:XP_011530263.1|refseq:XP_011530264.1|refseq:XP_011530265.1|refseq:XP_011530266.1|refseq:XP_005263049.1|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568|dip:DIP-38538N|ensembl:ENSG00000170365(gene)|ensembl:ENST00000302085(transcript)|ensembl:ENST00000394092(transcript)|ensembl:ENST00000515385(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007276"(gamete generation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042592"(homeostatic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15797|rcsb pdb:1KHU|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LAZ|rcsb pdb:2LB0|rcsb pdb:2LB1|rcsb pdb:3Q47|rcsb pdb:3Q4A|rcsb pdb:5ZOK|reactome:R-HSA-201451|reactome:R-HSA-5689880|reactome:R-HSA-8941326|entrezgene/locuslink:4086(identity) - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rogid:cdDNFpwLw2+hPeP0l6ArvDs3LMo9606 rigid:K2dWeGB+Bx/BwqQEFlJYdRFUhg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15797 uniprotkb:Q01844 intact:EBI-1567153|uniprotkb:Q16636|uniprotkb:D3DNZ9|uniprotkb:A8KAJ0|uniprotkb:Q9UFT8|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:smad1_human(display_long)|uniprotkb:Mad-related protein 1(gene name synonym)|uniprotkb:SMAD family member 1(gene name synonym)|uniprotkb:Transforming growth factor-beta-signaling protein 1(gene name synonym)|uniprotkb:JV4-1(gene name synonym)|uniprotkb:SMAD1(gene name)|psi-mi:SMAD1(display_short)|uniprotkb:BSP1(gene name synonym)|uniprotkb:MADH1(gene name synonym)|uniprotkb:MADR1(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678248|imex:IM-28774-2961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006714280.1|refseq:NP_001003688.1|refseq:NP_005891.1|refseq:XP_011530263.1|refseq:XP_011530264.1|refseq:XP_011530265.1|refseq:XP_011530266.1|refseq:XP_005263049.1|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568|dip:DIP-38538N|ensembl:ENSG00000170365(gene)|ensembl:ENST00000302085(transcript)|ensembl:ENST00000394092(transcript)|ensembl:ENST00000515385(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007276"(gamete generation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042592"(homeostatic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15797|rcsb pdb:1KHU|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LAZ|rcsb pdb:2LB0|rcsb pdb:2LB1|rcsb pdb:3Q47|rcsb pdb:3Q4A|rcsb pdb:5ZOK|reactome:R-HSA-201451|reactome:R-HSA-5689880|reactome:R-HSA-8941326|entrezgene/locuslink:4086(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cdDNFpwLw2+hPeP0l6ArvDs3LMo9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:S6J2x1d37Alfcs1Bk2VM+jBcOuc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D275 uniprotkb:P15066 intact:EBI-11017940|ensembl:ENSMUSP00000027943 intact:EBI-5347821|ensembl:ENSMUSP00000092901 psi-mi:batf3_mouse(display_long)|uniprotkb:Batf3(gene name)|psi-mi:Batf3(display_short) psi-mi:jund_mouse(display_long)|uniprotkb:Jund(gene name)|psi-mi:Jund(display_short)|uniprotkb:Jun-d(gene name synonym)|uniprotkb:Jund1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678240|imex:IM-28774-707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084336.1|ensembl:ENSMUSG00000026630(gene)|ensembl:ENSMUST00000027943(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029818|entrezgene/locuslink:381319(identity) refseq:NP_034722.1|ensembl:ENSMUSG00000071076(gene)|ensembl:ENSMUST00000095267(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002076"(osteoblast development)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029823|mint:P15066|entrezgene/locuslink:16478(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:38LRXmWGrAFjZsJf4XP4cMfhDpE10090 rogid:RGSsjYVfQJ1C1ZxQoxy4Q2NdE1g10090 rigid:m1ojReASXHM8eC/PGxdQ2i0dklc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D275 uniprotkb:P09450 intact:EBI-11017940|ensembl:ENSMUSP00000027943 intact:EBI-5347760|uniprotkb:Q8C2G9|ensembl:ENSMUSP00000064680 psi-mi:batf3_mouse(display_long)|uniprotkb:Batf3(gene name)|psi-mi:Batf3(display_short) psi-mi:junb_mouse(display_long)|uniprotkb:Junb(gene name)|psi-mi:Junb(display_short)|uniprotkb:Jun-b(gene name synonym)|uniprotkb:MyD21(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678232|imex:IM-28774-1201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084336.1|ensembl:ENSMUSG00000026630(gene)|ensembl:ENSMUST00000027943(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029818|entrezgene/locuslink:381319(identity) dip:DIP-1069N|refseq:NP_032442.1|ensembl:ENSMUSG00000052837(gene)|ensembl:ENSMUST00000064922(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009987"(cellular process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|entrezgene/locuslink:16477(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:38LRXmWGrAFjZsJf4XP4cMfhDpE10090 rogid:jnlW1k7KFty2J0v0PVptgt0oWVo10090 rigid:Zq9Kr+qTTM3S3d4TK5kFYSpQpyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D275 uniprotkb:P09450 intact:EBI-11017940|ensembl:ENSMUSP00000027943 intact:EBI-5347760|uniprotkb:Q8C2G9|ensembl:ENSMUSP00000064680 psi-mi:batf3_mouse(display_long)|uniprotkb:Batf3(gene name)|psi-mi:Batf3(display_short) psi-mi:junb_mouse(display_long)|uniprotkb:Junb(gene name)|psi-mi:Junb(display_short)|uniprotkb:Jun-b(gene name synonym)|uniprotkb:MyD21(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678224|imex:IM-28774-2533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084336.1|ensembl:ENSMUSG00000026630(gene)|ensembl:ENSMUST00000027943(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029818|entrezgene/locuslink:381319(identity) dip:DIP-1069N|refseq:NP_032442.1|ensembl:ENSMUSG00000052837(gene)|ensembl:ENSMUST00000064922(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009987"(cellular process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|entrezgene/locuslink:16477(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:38LRXmWGrAFjZsJf4XP4cMfhDpE10090 rogid:jnlW1k7KFty2J0v0PVptgt0oWVo10090 rigid:Zq9Kr+qTTM3S3d4TK5kFYSpQpyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17275 uniprotkb:P01100 intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245 psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678216|imex:IM-28774-2959 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N|entrezgene/locuslink:3726(identity) refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638|entrezgene/locuslink:2353(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606 rigid:hRGxhC6DyIpMTCNcch6jDUvzGMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14896 uniprotkb:O43763 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678208|imex:IM-28774-2119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|entrezgene/locuslink:3664(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:rMM65aWormVUXvpkob3qjINy53I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15306 uniprotkb:O43248 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678200|imex:IM-28774-1199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:1wLYNb9jTpsBKlza10jKTquxQ/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14653 uniprotkb:Q01844 intact:EBI-2650369|uniprotkb:Q5FBY1|uniprotkb:Q5FBY2|uniprotkb:Q7Z5G6|uniprotkb:A8K7L2|uniprotkb:B2RAZ3|ensembl:ENSP00000310127|ensembl:ENSP00000366344|ensembl:ENSP00000469113|uniprotkb:Q5FBY4 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:irf3_human(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678192|imex:IM-28774-2117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001562.1|refseq:NP_001184053.1|ensembl:ENSG00000126456(gene)|ensembl:ENST00000309877(transcript)|ensembl:ENST00000377139(transcript)|ensembl:ENST00000597198(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071888"(macrophage apoptotic process)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q14653|rcsb pdb:1J2F|rcsb pdb:1QWT|rcsb pdb:1T2K|rcsb pdb:1ZOQ|rcsb pdb:2O61|rcsb pdb:2O6G|rcsb pdb:2PI0|rcsb pdb:3A77|rcsb pdb:3QU6|rcsb pdb:5JEJ|rcsb pdb:5JEK|rcsb pdb:5JEL|rcsb pdb:5JEM|rcsb pdb:5JEO|rcsb pdb:5JER|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:7JFL|reactome:R-HSA-1169408|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3270619|reactome:R-HSA-877300|reactome:R-HSA-3134973|reactome:R-HSA-9013973|reactome:R-HSA-909733|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|refseq:NP_001184051.1|refseq:NP_001184052.1|refseq:NP_001184054.1|refseq:NP_001184055.1|refseq:NP_001184056.1|refseq:NP_001184057.1|refseq:XP_006723260.1|refseq:XP_006723261.1|refseq:XP_016882255.1|refseq:XP_016882256.1|dip:DIP-41448N|entrezgene/locuslink:3661(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hQC59YXQ7BOkhZzKbxYHcu1YWFA9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:Ytt1ePAtw1GSR7yg7kZ6qm1f5Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HB58 uniprotkb:Q13761 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-925990|uniprotkb:Q12969|uniprotkb:Q13760|intact:EBI-1046821|uniprotkb:B1AJV5|ensembl:ENSP00000308051 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:runx3_human(display_long)|uniprotkb:RUNX3(gene name)|psi-mi:RUNX3(display_short)|uniprotkb:AML2(gene name synonym)|uniprotkb:CBFA3(gene name synonym)|uniprotkb:PEBP2A3(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-3(gene name synonym)|uniprotkb:Acute myeloid leukemia 2 protein(gene name synonym)|uniprotkb:Oncogene AML-2(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha C subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha C subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha C subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678184|imex:IM-28774-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|entrezgene/locuslink:3431(identity) ensembl:ENSP00000308051|ensembl:ENST00000338888|ensembl:ENSP00000343477|ensembl:ENST00000399916|ensembl:ENSP00000382800|refseq:NP_001026850.1|refseq:NP_004341.1|refseq:NP_001307601.1|refseq:XP_005246081.1|ensembl:ENSG00000020633(gene)|ensembl:ENST00000308873(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|rcsb pdb:5W69|reactome:R-HSA-4411364|reactome:R-HSA-8941855|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8949275|reactome:R-HSA-8951430|reactome:R-HSA-8951671|reactome:R-HSA-8951911|reactome:R-HSA-8951936|reactome:R-HSA-8952158|entrezgene/locuslink:864(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:NfQJ1nSJCmrYMhsb6PRSwY58UcI9606 rigid:Jp6oHRsXFn8KX8AaztHm54Ul7kQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06455 uniprotkb:Q02535 intact:EBI-743342|uniprotkb:O14784|uniprotkb:Q06456|uniprotkb:Q14873|uniprotkb:Q16239|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q6IBL1|uniprotkb:Q92479|uniprotkb:Q9BRZ0|ensembl:ENSP00000265814|ensembl:ENSP00000428543|ensembl:ENSP00000481112|ensembl:ENSP00000481315|ensembl:ENSP00000481799|uniprotkb:B7Z4P4|uniprotkb:E7EPN4|uniprotkb:Q6NXH1|uniprotkb:Q7Z4J5 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:mtg8_human(display_long)|uniprotkb:Protein MTG8(gene name synonym)|uniprotkb:Protein ETO(gene name synonym)|uniprotkb:Eight twenty one protein(gene name synonym)|uniprotkb:Cyclin-D-related protein(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 2(gene name synonym)|uniprotkb:RUNX1T1(gene name)|psi-mi:RUNX1T1(display_short)|uniprotkb:AML1T1(gene name synonym)|uniprotkb:CBFA2T1(gene name synonym)|uniprotkb:CDR(gene name synonym)|uniprotkb:ETO(gene name synonym)|uniprotkb:MTG8(gene name synonym)|uniprotkb:ZMYND2(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678176|imex:IM-28774-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185554.1|refseq:NP_001185555.1|refseq:NP_001185556.1|refseq:NP_001185557.1|refseq:NP_001185558.1|refseq:NP_001185559.1|refseq:NP_001185560.1|refseq:NP_001185561.1|refseq:NP_004340.1|refseq:NP_783552.1|refseq:NP_783553.1|refseq:NP_783554.1|ensembl:ENSG00000079102(gene)|ensembl:ENST00000265814(transcript)|ensembl:ENST00000523629(transcript)|ensembl:ENST00000613302(transcript)|ensembl:ENST00000614812(transcript)|ensembl:ENST00000617740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|refseq:XP_011515653.1|refseq:XP_011515654.1|refseq:XP_011515655.1|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:Q06455|rcsb pdb:1WQ6|rcsb pdb:2DJ8|rcsb pdb:2H7B|rcsb pdb:2KNH|rcsb pdb:2KYG|rcsb pdb:2OD1|rcsb pdb:2ODD|rcsb pdb:2PP4|rcsb pdb:4JOL|refseq:NP_001185563.1|refseq:NP_001185562.1|refseq:NP_001185608.1|refseq:XP_006716739.1|refseq:XP_016869420.1|refseq:XP_016869421.1|refseq:XP_016869422.1|refseq:XP_016869423.1|refseq:XP_016869424.1|refseq:XP_016869425.1|refseq:XP_016869426.1|dip:DIP-29401N|entrezgene/locuslink:862(identity) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SMomKOZSbtqhKiAkkUkabKbC8/09606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rigid:WmHEU4FG+3bbqDOW/aYeqePVGu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:Q16254 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-448943|uniprotkb:A6NGR8|uniprotkb:Q12991|uniprotkb:Q15328|uniprotkb:B5BU56|ensembl:ENSP00000368686 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:e2f4_human(display_long)|uniprotkb:E2F4(gene name)|psi-mi:E2F4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678168|imex:IM-28774-2115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) refseq:NP_001941.2|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|ensembl:ENSG00000205250(gene)|ensembl:ENST00000379378(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098534"(centriole assembly)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR028312|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q16254|rcsb pdb:1CF7|rcsb pdb:5TUU|reactome:R-HSA-1362277|dip:DIP-24185N|entrezgene/locuslink:1874(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:t0tCW85omHMU3lVgYWEXNeX1sTI9606 rigid:O1lhc29mxz4E9Wxgre/FT6AOkqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BKT3 uniprotkb:Q07279 intact:EBI-26678080|ensembl:ENSMUSP00000035644|uniprotkb:Q3UWF7|uniprotkb:Q8BK44 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:gcfc2_mouse(display_long)|uniprotkb:GC-rich sequence DNA-binding factor(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor 2(gene name synonym)|uniprotkb:Transcription factor 9(gene name synonym)|uniprotkb:Gcfc2(gene name)|psi-mi:Gcfc2(display_short)|uniprotkb:Gcf(gene name synonym)|uniprotkb:Tcf9(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678119|imex:IM-28774-3375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035125(gene)|ensembl:ENSMUST00000043195(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR012890(GC-rich sequence DNA-binding factor-like)|interpro:IPR022783|reactome:R-MMU-72163|refseq:NP_808552.2|entrezgene/locuslink:330361(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:evSIibclK45gQT6ARuARyWJeBcg10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:pxIFRs58x9MWWLzfFWJSJH6SlDE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16621 uniprotkb:Q9UKW6 intact:EBI-726369|uniprotkb:Q07720|uniprotkb:Q6ICV9|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558 intact:EBI-747605|uniprotkb:O95175|uniprotkb:Q8N2K9|uniprotkb:Q96QY3|uniprotkb:Q9UKW5|uniprotkb:A8K452|uniprotkb:A6XAE6|ensembl:ENSP00000311010 psi-mi:nfe2_human(display_long)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:NFE2(gene name)|psi-mi:NFE2(display_short) psi-mi:elf5_human(display_long)|uniprotkb:E74-like factor 5(gene name synonym)|uniprotkb:Epithelium-specific Ets transcription factor 2(gene name synonym)|uniprotkb:Epithelium-restricted ESE-1-related Ets factor(gene name synonym)|uniprotkb:ELF5(gene name)|psi-mi:ELF5(display_short)|uniprotkb:ESE2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678432|imex:IM-28774-3377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248390.1|refseq:NP_001129495.1|refseq:NP_006154.1|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558|refseq:XP_005268963.1|ensembl:ENSG00000123405(gene)|ensembl:ENST00000312156(transcript)|ensembl:ENST00000435572(transcript)|ensembl:ENST00000540264(transcript)|ensembl:ENST00000553070(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007599"(hemostasis)|go:"GO:0016605"(PML body)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|rcsb pdb:1LVX|rcsb pdb:2KZ5|reactome:R-HSA-8936459|reactome:R-HSA-983231|dip:DIP-57844N|entrezgene/locuslink:4778(identity) refseq:NP_001413.1|refseq:NP_938195.1|refseq:NP_001230009.1|refseq:NP_001230010.1|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033069|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WWX|go:"GO:0030154"(cell differentiation)|ensembl:ENSG00000135374(gene)|ensembl:ENST00000312319(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:2001(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Y8uGUXDj1DbJnvZT2aZ5suX/yDE9606 rogid:FrgZm5Qx+Ox5xjZJ+rtnGdEbRB49606 rigid:Ov2HsrBwdkdG43QOSVW84b2AHXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92886 uniprotkb:Q06455 intact:EBI-10279647|uniprotkb:Q96HE1|uniprotkb:Q5U0Q9|ensembl:ENSP00000317580 intact:EBI-743342|uniprotkb:O14784|uniprotkb:Q06456|uniprotkb:Q14873|uniprotkb:Q16239|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q6IBL1|uniprotkb:Q92479|uniprotkb:Q9BRZ0|ensembl:ENSP00000265814|ensembl:ENSP00000428543|ensembl:ENSP00000481112|ensembl:ENSP00000481315|ensembl:ENSP00000481799|uniprotkb:B7Z4P4|uniprotkb:E7EPN4|uniprotkb:Q6NXH1|uniprotkb:Q7Z4J5 psi-mi:ngn1_human(display_long)|uniprotkb:NEUROG1(gene name)|psi-mi:NEUROG1(display_short)|uniprotkb:BHLHA6(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 6(gene name synonym)|uniprotkb:NEUROD3(gene name synonym)|uniprotkb:NGN(gene name synonym)|uniprotkb:NGN1(gene name synonym)|uniprotkb:Neurogenic basic-helix-loop-helix protein(gene name synonym)|uniprotkb:Neurogenic differentiation factor 3(gene name synonym) psi-mi:mtg8_human(display_long)|uniprotkb:Protein MTG8(gene name synonym)|uniprotkb:Protein ETO(gene name synonym)|uniprotkb:Eight twenty one protein(gene name synonym)|uniprotkb:Cyclin-D-related protein(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 2(gene name synonym)|uniprotkb:RUNX1T1(gene name)|psi-mi:RUNX1T1(display_short)|uniprotkb:AML1T1(gene name synonym)|uniprotkb:CBFA2T1(gene name synonym)|uniprotkb:CDR(gene name synonym)|uniprotkb:ETO(gene name synonym)|uniprotkb:MTG8(gene name synonym)|uniprotkb:ZMYND2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678424|imex:IM-28774-1631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006152.2|ensembl:ENSG00000181965(gene)|ensembl:ENST00000314744(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0007399"(nervous system development)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032653|interpro:IPR036638|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:4762(identity) refseq:NP_001185554.1|refseq:NP_001185555.1|refseq:NP_001185556.1|refseq:NP_001185557.1|refseq:NP_001185558.1|refseq:NP_001185559.1|refseq:NP_001185560.1|refseq:NP_001185561.1|refseq:NP_004340.1|refseq:NP_783552.1|refseq:NP_783553.1|refseq:NP_783554.1|ensembl:ENSG00000079102(gene)|ensembl:ENST00000265814(transcript)|ensembl:ENST00000523629(transcript)|ensembl:ENST00000613302(transcript)|ensembl:ENST00000614812(transcript)|ensembl:ENST00000617740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|refseq:XP_011515653.1|refseq:XP_011515654.1|refseq:XP_011515655.1|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:Q06455|rcsb pdb:1WQ6|rcsb pdb:2DJ8|rcsb pdb:2H7B|rcsb pdb:2KNH|rcsb pdb:2KYG|rcsb pdb:2OD1|rcsb pdb:2ODD|rcsb pdb:2PP4|rcsb pdb:4JOL|refseq:NP_001185563.1|refseq:NP_001185562.1|refseq:NP_001185608.1|refseq:XP_006716739.1|refseq:XP_016869420.1|refseq:XP_016869421.1|refseq:XP_016869422.1|refseq:XP_016869423.1|refseq:XP_016869424.1|refseq:XP_016869425.1|refseq:XP_016869426.1|dip:DIP-29401N|entrezgene/locuslink:862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kz1JEusy5ubX6GwV80OmH4UQFEQ9606 rogid:SMomKOZSbtqhKiAkkUkabKbC8/09606 rigid:n8nHNOt9LfpFq2cQ6mBciWSokfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q8CDC7 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-5745724|uniprotkb:Q3U3B2|uniprotkb:Q9CYQ0|ensembl:ENSMUSP00000112778|ensembl:ENSMUSP00000115777|ensembl:ENSMUSP00000157541 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:zbtb9_mouse(display_long)|uniprotkb:Zbtb9(gene name)|psi-mi:Zbtb9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678416|imex:IM-28774-721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_001005916.1|ensembl:ENSMUSG00000079605(gene)|ensembl:ENSMUSG00000117819(gene)|ensembl:ENSMUST00000120016(transcript)|ensembl:ENSMUST00000133257(transcript)|ensembl:ENSMUST00000237633(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:474156(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:xLE8GzacyDwkYXFu/6TgVF0ytS410090 rigid:ObFDRi6YAbo4D/iEcv/vkG69QgY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q8CDC7 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-5745724|uniprotkb:Q3U3B2|uniprotkb:Q9CYQ0|ensembl:ENSMUSP00000112778|ensembl:ENSMUSP00000115777|ensembl:ENSMUSP00000157541 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:zbtb9_mouse(display_long)|uniprotkb:Zbtb9(gene name)|psi-mi:Zbtb9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678408|imex:IM-28774-2539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) refseq:NP_001005916.1|ensembl:ENSMUSG00000079605(gene)|ensembl:ENSMUSG00000117819(gene)|ensembl:ENSMUST00000120016(transcript)|ensembl:ENSMUST00000133257(transcript)|ensembl:ENSMUST00000237633(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:474156(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:xLE8GzacyDwkYXFu/6TgVF0ytS410090 rigid:vVEyXklZ2PKgnT4jN4781NsuLvk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35548 uniprotkb:P05423 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678368|imex:IM-28774-1207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:eP1ijxKvPA6Ev3d/x6KFbR7/Tls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CDC7 uniprotkb:Q62240 intact:EBI-5745724|uniprotkb:Q3U3B2|uniprotkb:Q9CYQ0|ensembl:ENSMUSP00000112778|ensembl:ENSMUSP00000115777|ensembl:ENSMUSP00000157541 intact:EBI-26672525|ensembl:ENSMUSP00000061095|uniprotkb:Q3US03|uniprotkb:Q6PCX3|uniprotkb:Q9QVR9|uniprotkb:Q9R040 psi-mi:zbtb9_mouse(display_long)|uniprotkb:Zbtb9(gene name)|psi-mi:Zbtb9(display_short) psi-mi:kdm5d_mouse(display_long)|uniprotkb:Histocompatibility Y antigen(gene name synonym)|uniprotkb:Histone demethylase JARID1D(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1D(gene name synonym)|uniprotkb:Protein SmcY(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5D"(gene name synonym)|uniprotkb:Kdm5d(gene name)|psi-mi:Kdm5d(display_short)|uniprotkb:Hya(gene name synonym)|uniprotkb:Jarid1d(gene name synonym)|uniprotkb:Smcy(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678392|imex:IM-28774-719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005916.1|ensembl:ENSMUSG00000079605(gene)|ensembl:ENSMUSG00000117819(gene)|ensembl:ENSMUST00000120016(transcript)|ensembl:ENSMUST00000133257(transcript)|ensembl:ENSMUST00000237633(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:474156(identity) ensembl:ENSMUSG00000056673(gene)|ensembl:ENSMUST00000055032(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0002457"(T cell antigen processing and presentation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|reactome:R-MMU-3214842|refseq:NP_035549.1|entrezgene/locuslink:20592(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xLE8GzacyDwkYXFu/6TgVF0ytS410090 rogid:Xykgc4tH/CogBi2mYeFRKkL9JXY10090 rigid:bRjA+HVA5XJPqEJJVS2uZr+1YfY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULW6 uniprotkb:Q9HB58 intact:EBI-3911716|ensembl:ENSP00000362616|uniprotkb:B4E161|uniprotkb:Q8TAN6|uniprotkb:B2RE61 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 psi-mi:np1l2_human(display_long)|uniprotkb:NAP1L2(gene name)|psi-mi:NAP1L2(display_short)|uniprotkb:BPX(gene name synonym)|uniprotkb:Brain-specific protein, X-linked(gene name synonym) psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678384|imex:IM-28774-1627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186462(gene)|ensembl:ENST00000373517(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|refseq:NP_068798.1|entrezgene/locuslink:4674(identity) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|entrezgene/locuslink:3431(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sADEPPkWzPLMnI5dl4GQt86KHZU9606 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rigid:b8x6QKvP1j+icUSoATRBNwpeZLA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10242 uniprotkb:Q16534 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-2798854|uniprotkb:A8K1X8|uniprotkb:Q6FHS9|ensembl:ENSP00000226067 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:hlf_human(display_long)|uniprotkb:HLF(gene name)|psi-mi:HLF(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678376|imex:IM-28774-1209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|entrezgene/locuslink:4602(identity) refseq:NP_002117.1|refseq:NP_001317304.1|ensembl:ENSG00000108924(gene)|ensembl:ENST00000226067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029829|interpro:IPR040223|entrezgene/locuslink:3131(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:PW5bjFvr3rzfK+vMdfMKNj0gw9M9606 rigid:EE6vub0xpymsf1nzeTmncWN6tKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70271 uniprotkb:Q8CDC7 intact:EBI-7288319|intact:MINT-4106929|uniprotkb:Q5SWV2|uniprotkb:Q8K0W4|ensembl:ENSMUSP00000018755 intact:EBI-5745724|uniprotkb:Q3U3B2|uniprotkb:Q9CYQ0|ensembl:ENSMUSP00000112778|ensembl:ENSMUSP00000115777|ensembl:ENSMUSP00000157541 psi-mi:pdli4_mouse(display_long)|uniprotkb:Pdlim4(gene name)|psi-mi:Pdlim4(display_short)|uniprotkb:Ril(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:zbtb9_mouse(display_long)|uniprotkb:Zbtb9(gene name)|psi-mi:Zbtb9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678400|imex:IM-28774-1629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062290.2|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0043197"(dendritic spine)|ensembl:ENSMUSG00000020388(gene)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|mint:P70271|ensembl:ENSMUST00000018755(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|entrezgene/locuslink:30794(identity) refseq:NP_001005916.1|ensembl:ENSMUSG00000079605(gene)|ensembl:ENSMUSG00000117819(gene)|ensembl:ENSMUST00000120016(transcript)|ensembl:ENSMUST00000133257(transcript)|ensembl:ENSMUST00000237633(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:474156(identity) - comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0p7CYiGd3Vpz5qQL07CNcRse+NQ10090 rogid:xLE8GzacyDwkYXFu/6TgVF0ytS410090 rigid:xd29PmVQG2maY9mYVQIUwPIdIoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57086 uniprotkb:Q16621 intact:EBI-745846|uniprotkb:Q6IAG7|ensembl:ENSP00000301995|ensembl:ENSP00000363103|ensembl:ENSP00000481289 intact:EBI-726369|uniprotkb:Q07720|uniprotkb:Q6ICV9|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558 psi-mi:scnd1_human(display_long)|uniprotkb:SCAND1(gene name)|psi-mi:SCAND1(display_short)|uniprotkb:SDP1(gene name synonym) psi-mi:nfe2_human(display_long)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:NFE2(gene name)|psi-mi:NFE2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678672|imex:IM-28774-1645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057642.1|ensembl:ENSG00000171222(gene)|ensembl:ENST00000305978(transcript)|ensembl:ENST00000373991(transcript)|ensembl:ENST00000615116(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269|refseq:NP_361012.2|entrezgene/locuslink:51282(identity) refseq:NP_001248390.1|refseq:NP_001129495.1|refseq:NP_006154.1|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558|refseq:XP_005268963.1|ensembl:ENSG00000123405(gene)|ensembl:ENST00000312156(transcript)|ensembl:ENST00000435572(transcript)|ensembl:ENST00000540264(transcript)|ensembl:ENST00000553070(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007599"(hemostasis)|go:"GO:0016605"(PML body)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|rcsb pdb:1LVX|rcsb pdb:2KZ5|reactome:R-HSA-8936459|reactome:R-HSA-983231|dip:DIP-57844N|entrezgene/locuslink:4778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PYwugMdd/3klI5aAelQle8pGoMQ9606 rogid:Y8uGUXDj1DbJnvZT2aZ5suX/yDE9606 rigid:vrFhlHIQf67fmbrjRxJQsWuWPrg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P57086 uniprotkb:O95125 intact:EBI-745846|uniprotkb:Q6IAG7|ensembl:ENSP00000301995|ensembl:ENSP00000363103|ensembl:ENSP00000481289 intact:EBI-751960|uniprotkb:Q4JG21|uniprotkb:Q9H1B9|uniprotkb:Q9NSM4|uniprotkb:B0LPH9|ensembl:ENSP00000337724|ensembl:ENSP00000432504|ensembl:ENSP00000433881 psi-mi:scnd1_human(display_long)|uniprotkb:SCAND1(gene name)|psi-mi:SCAND1(display_short)|uniprotkb:SDP1(gene name synonym) psi-mi:zn202_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 10(gene name synonym)|uniprotkb:ZNF202(gene name)|psi-mi:ZNF202(display_short)|uniprotkb:ZKSCAN10(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678680|imex:IM-28774-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057642.1|ensembl:ENSG00000171222(gene)|ensembl:ENST00000305978(transcript)|ensembl:ENST00000373991(transcript)|ensembl:ENST00000615116(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269|refseq:NP_361012.2|entrezgene/locuslink:51282(identity) refseq:NP_003446.2|refseq:XP_011541274.1|refseq:XP_011541275.1|refseq:XP_011541277.1|refseq:XP_011541278.1|refseq:XP_006718964.1|refseq:NP_001288708.1|refseq:NP_001288709.1|refseq:NP_001288748.1|refseq:XP_005271716.1|refseq:XP_005271717.1|refseq:XP_005271718.1|refseq:XP_005271721.1|refseq:XP_016873757.1|ensembl:ENSG00000166261(gene)|ensembl:ENST00000336139(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENST00000529691(transcript)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|ensembl:ENST00000530393(transcript)|entrezgene/locuslink:7753(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PYwugMdd/3klI5aAelQle8pGoMQ9606 rogid:FXrtMKvDgz/dl5LmowdFVgYi65w9606 rigid:VztAS4wfbrED53J3KD/BYFSbIpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35548 uniprotkb:Q9UIJ5 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 intact:EBI-26466319|ensembl:ENSP00000262096|uniprotkb:D3DSP5 psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:zdhc2_human(display_long)|uniprotkb:ZDHHC2(gene name)|psi-mi:ZDHHC2(display_short)|uniprotkb:REAM(gene name synonym)|uniprotkb:REC(gene name synonym)|uniprotkb:ZNF372(gene name synonym)|uniprotkb:Acyltransferase ZDHHC2(gene name synonym)|uniprotkb:Reduced expression associated with metastasis protein(gene name synonym)|uniprotkb:Reduced expression in cancer protein(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger protein 372(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678656|imex:IM-28774-3385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) ensembl:ENSG00000104219(gene)|ensembl:ENST00000262096(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1905751"(positive regulation of endosome to plasma membrane protein transport)|interpro:IPR001594(Zinc finger, DHHC-type)|reactome:R-HSA-5683826|refseq:NP_057437.1|entrezgene/locuslink:51201(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rogid:sboNX/lElOYDVB0KAyHbdi+E+z49606 rigid:T83wchuhWK8YbhWj+zdUKYBe8dM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q9UK33 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-746277|uniprotkb:Q9NPP7|uniprotkb:B2RC05|ensembl:ENSP00000320050|ensembl:ENSP00000443957|ensembl:ENSP00000446126 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:zn580_human(display_long)|uniprotkb:LDL-induced EC protein(gene name synonym)|uniprotkb:ZNF580(gene name)|psi-mi:ZNF580(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678648|imex:IM-28774-1643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) ensembl:ENST00000545125(transcript)|refseq:NP_001156895.1|refseq:NP_057286.1|refseq:NP_996998.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0046872"(metal ion binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000785"(chromatin)|ensembl:ENSG00000213015(gene)|ensembl:ENST00000325333(transcript)|ensembl:ENST00000543039(transcript)|entrezgene/locuslink:51157(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:BoXqomubQMq/w1i89e93Vo7CLCs9606 rigid:hBq96hxA37yZzeo7riPxBnukrrg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UK33 uniprotkb:P55771 intact:EBI-746277|uniprotkb:Q9NPP7|uniprotkb:B2RC05|ensembl:ENSP00000320050|ensembl:ENSP00000443957|ensembl:ENSP00000446126 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:zn580_human(display_long)|uniprotkb:LDL-induced EC protein(gene name synonym)|uniprotkb:ZNF580(gene name)|psi-mi:ZNF580(display_short) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678640|imex:IM-28774-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000545125(transcript)|refseq:NP_001156895.1|refseq:NP_057286.1|refseq:NP_996998.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0046872"(metal ion binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000785"(chromatin)|ensembl:ENSG00000213015(gene)|ensembl:ENST00000325333(transcript)|ensembl:ENST00000543039(transcript)|entrezgene/locuslink:51157(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BoXqomubQMq/w1i89e93Vo7CLCs9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:2q1xkp2ffDQfoX83aSKXyN1aRtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNL4 uniprotkb:P17482 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678632|imex:IM-28774-2969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|entrezgene/locuslink:51147(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:K56EPVLaDBHk8ZJmTrqy12+FNNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNL4 uniprotkb:O43711 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678624|imex:IM-28774-2549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|entrezgene/locuslink:51147(identity) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rigid:o1RvbhVYXIvg+sW70kJGRXVBCrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNL4 uniprotkb:Q9NQC1 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q6IE80|uniprotkb:Q96GQ6|ensembl:ENSP00000378451 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678616|imex:IM-28774-2547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|entrezgene/locuslink:51147(identity) refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|mint:Q9NQC1|reactome:R-HSA-3214847|entrezgene/locuslink:23338(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 rigid:M3pi+Uziq0NzPtF6Gg1YTwlpZRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVW2 uniprotkb:P42226 intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678608|imex:IM-28774-2967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168|entrezgene/locuslink:51132(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:WZ729sG32U0S58H7rhEjFdfgPCY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVW2 uniprotkb:O75177 intact:EBI-1996544|uniprotkb:Q9Y598|uniprotkb:Q96D38|uniprotkb:D3DTE0|uniprotkb:B2RBQ1|ensembl:ENSP00000253571|ensembl:ENSP00000328059 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:rnf12_human(display_long)|uniprotkb:RLIM(gene name)|psi-mi:RLIM(display_short)|uniprotkb:RNF12(gene name synonym)|uniprotkb:RING finger protein 12(gene name synonym)|uniprotkb:LIM domain-interacting RING finger protein(gene name synonym)|uniprotkb:RING finger LIM domain-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-43(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RLIM(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678600|imex:IM-28774-2125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057204.2|refseq:NP_899196.1|ensembl:ENSG00000131263(gene)|ensembl:ENST00000332687(transcript)|ensembl:ENST00000349225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060816"(random inactivation of X chromosome)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900095"(regulation of dosage compensation by inactivation of X chromosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NVW2|rcsb pdb:6W7Z|rcsb pdb:6W9A|rcsb pdb:6W9D|reactome:R-HSA-983168|entrezgene/locuslink:51132(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jEHiOt7hjZc5HU6E/XQGE7zdZbw9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:N4ntpsnVcz3ewnF8ZvWZEDWDho0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15156 uniprotkb:Q9NRM2 intact:EBI-740434|ensembl:ENSP00000292176|ensembl:ENSP00000357411|ensembl:ENSP00000438647|uniprotkb:Q68DR2|uniprotkb:Q96EP2|uniprotkb:D3DV83|uniprotkb:B4E3K5|uniprotkb:J3KQQ3 intact:EBI-949305|ensembl:ENSP00000354501|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14 psi-mi:zbt7b_human(display_long)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym) psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678592|imex:IM-28774-1641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160685(gene)|ensembl:ENST00000292176(transcript)|refseq:NP_001239335.1|refseq:NP_001243384.1|refseq:XP_006711412.2|ensembl:ENSP00000292176|ensembl:ENSP00000357411|ensembl:ENST00000417934|ensembl:ENSP00000406286|ensembl:ENSP00000438647|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0007595"(lactation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENST00000368426(transcript)|ensembl:ENST00000535420(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:XP_011507900.1|refseq:XP_011507901.1|refseq:XP_006711416.1|refseq:XP_006711417.1|refseq:XP_006711419.1|refseq:XP_006711420.1|refseq:XP_006711421.1|refseq:XP_006711422.1|entrezgene/locuslink:51043(identity) ensembl:ENSG00000198839(gene)|ensembl:ENST00000361822(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_068834.2|entrezgene/locuslink:11179(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Gzf1loNaGwiZWBInG77RQn3f+9c9606 rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606 rigid:ZzRz1hbmol/n5KtAjv+B1XLuFAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00488 uniprotkb:Q9P1U0 intact:EBI-726769|uniprotkb:B2R4S0|uniprotkb:Q5T2H7|ensembl:ENSP00000363384 intact:EBI-355434|ensembl:ENSP00000407364|ensembl:ENSP00000407715|ensembl:ENSP00000410127|ensembl:ENSP00000410530|ensembl:ENSP00000410954|ensembl:ENSP00000412369|ensembl:ENSP00000413265|ensembl:ENSP00000414110|ensembl:ENSP00000414720|ensembl:ENSP00000416599|ensembl:ENSP00000405636|ensembl:ENSP00000331111|ensembl:ENSP00000352333|ensembl:ENSP00000365978|ensembl:ENSP00000365981|ensembl:ENSP00000373108|ensembl:ENSP00000383500|ensembl:ENSP00000383501|ensembl:ENSP00000383503|ensembl:ENSP00000387914|ensembl:ENSP00000391809|ensembl:ENSP00000393236|ensembl:ENSP00000394779|ensembl:ENSP00000395065|ensembl:ENSP00000395397|ensembl:ENSP00000396661|ensembl:ENSP00000396922|ensembl:ENSP00000397636|ensembl:ENSP00000399302|ensembl:ENSP00000399966|ensembl:ENSP00000402198|ensembl:ENSP00000405264 psi-mi:zn593_human(display_long)|uniprotkb:Zinc finger protein T86(gene name synonym)|uniprotkb:ZNF593(gene name)|psi-mi:ZNF593(display_short)|uniprotkb:ZT86(gene name synonym) psi-mi:rpa12_human(display_long)|uniprotkb:POLR1H(gene name)|psi-mi:POLR1H(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit H(gene name synonym)|uniprotkb:RPA12(gene name synonym)|uniprotkb:ZNRD1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678584|imex:IM-28774-1639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056955.2|ensembl:ENSG00000142684(gene)|ensembl:ENST00000374266(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|rcsb pdb:1ZR9|rcsb pdb:6LSS|rcsb pdb:6LU8|entrezgene/locuslink:51042(identity) refseq:NP_055411.1|refseq:NP_740753.1|refseq:NP_001265714.1|refseq:NP_001265715.1|ensembl:ENST00000332435(transcript)|ensembl:ENST00000359374(transcript)|ensembl:ENST00000376782(transcript)|ensembl:ENST00000376785(transcript)|ensembl:ENST00000383613(transcript)|ensembl:ENST00000400659(transcript)|ensembl:ENST00000400660(transcript)|ensembl:ENST00000400662(transcript)|ensembl:ENST00000412396(transcript)|ensembl:ENST00000417275(transcript)|ensembl:ENST00000417738(transcript)|ensembl:ENST00000420100(transcript)|ensembl:ENST00000428913(transcript)|ensembl:ENST00000429558(transcript)|ensembl:ENST00000431032(transcript)|ensembl:ENST00000431416(transcript)|ensembl:ENST00000432227(transcript)|ensembl:ENST00000432545(transcript)|ensembl:ENST00000432904(transcript)|ensembl:ENST00000433264(transcript)|ensembl:ENST00000437373(transcript)|ensembl:ENST00000437507(transcript)|ensembl:ENST00000441251(transcript)|ensembl:ENST00000442585(transcript)|ensembl:ENST00000443142(transcript)|ensembl:ENST00000443494(transcript)|ensembl:ENST00000444027(transcript)|ensembl:ENST00000444794(transcript)|ensembl:ENST00000446493(transcript)|ensembl:ENST00000451875(transcript)|ensembl:ENST00000455948(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|mint:Q9P1U0|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|ensembl:ENST00000453694(transcript)|ensembl:ENSG00000066379(gene)|ensembl:ENSG00000206502(gene)|ensembl:ENSG00000224859(gene)|ensembl:ENSG00000233795(gene)|ensembl:ENSG00000235176(gene)|ensembl:ENSG00000235443(gene)|ensembl:ENSG00000236808(gene)|ensembl:ENSG00000236949(gene)|entrezgene/locuslink:30834(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AhrvTeBvx2U76x+1pY/U/q3FNK49606 rogid:zWLcgopYhtpCPeyhS887IK1ZhNw9606 rigid:7QlbL4J+kDO4nbJXz3suEZ11zXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3C7 uniprotkb:O43513 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678576|imex:IM-28774-2965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:51003(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:PWWaJXlOIR8yU1PBcpnt924ROIM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61457 uniprotkb:P61457 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678560|imex:IM-28774-3383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:PR8uVOlZkvZz1ZO/v+0duPewhCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61457 uniprotkb:P19838 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 intact:EBI-300010|ensembl:ENSP00000378297|ensembl:ENSP00000424790|uniprotkb:Q68D84|uniprotkb:Q86V43|uniprotkb:Q8N4X7|uniprotkb:Q9NZC0|uniprotkb:A8K5Y5|uniprotkb:B3KVE8 psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:nfkb1_human(display_long)|uniprotkb:NFKB1(gene name)|psi-mi:NFKB1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678552|imex:IM-28774-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-5684264|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9609690|reactome:R-HSA-9660826|reactome:R-HSA-448706|ensembl:ENSG00000109320(gene)|ensembl:ENST00000394820(transcript)|ensembl:ENST00000505458(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1904385"(cellular response to angiotensin)|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P19838|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1NFI|rcsb pdb:1SVC|rcsb pdb:2DBF|rcsb pdb:2O61|rcsb pdb:3GUT|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|refseq:NP_001158884.1|refseq:NP_003989.2|refseq:NP_001306155.1|dip:DIP-106N|entrezgene/locuslink:4790(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rogid:Kb83YHl5j5+iZl8v3ERcD8CGNH89606 rigid:wbqAXy4cxAhoozGj8Cs4Y/4L//Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61457 uniprotkb:P41235 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 intact:EBI-1049011|uniprotkb:Q92654|uniprotkb:Q92655|uniprotkb:Q99864|uniprotkb:Q9NQH0|uniprotkb:O00659|uniprotkb:O00723|uniprotkb:Q14540|uniprotkb:Q5QPB8|uniprotkb:Q6B4V5|uniprotkb:Q6B4V6|uniprotkb:Q6B4V7|uniprotkb:Q92653|uniprotkb:A5JW41|uniprotkb:B2RPP8|ensembl:ENSP00000312987 psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:hnf4a_human(display_long)|uniprotkb:Transcription factor HNF-4(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:HNF4A(gene name)|psi-mi:HNF4A(display_short)|uniprotkb:HNF4(gene name synonym)|uniprotkb:NR2A1(gene name synonym)|uniprotkb:TCF14(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678544|imex:IM-28774-727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) refseq:NP_000448.3|refseq:NP_001025174.1|refseq:NP_001025175.1|refseq:NP_787110.2|refseq:NP_849181.1|refseq:NP_001274111.1|refseq:NP_001274112.1|refseq:NP_001274113.1|refseq:NP_001245284.1|ensembl:ENSG00000101076(gene)|ensembl:ENST00000316099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060398"(regulation of growth hormone receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR039067|mint:P41235|rcsb pdb:1PZL|rcsb pdb:3CBB|rcsb pdb:3FS1|rcsb pdb:4B7W|rcsb pdb:4IQR|rcsb pdb:6CHT|reactome:R-HSA-210745|reactome:R-HSA-383280|dip:DIP-499N|entrezgene/locuslink:3172(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rogid:lul0rM/fHNAVsH3ZizbMOXPPL0k9606 rigid:j/lr7HqICnDIkU/jPc09lMSpggc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKN5 uniprotkb:Q9Z2U2 intact:EBI-1213712|ensembl:ENSMUSP00000061408 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 psi-mi:olig1_mouse(display_long)|uniprotkb:Olig1(gene name)|psi-mi:Olig1(display_short)|uniprotkb:Oligodendrocyte-specific bHLH transcription factor 1(gene name synonym) psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678536|imex:IM-28774-1637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058664.2|ensembl:ENSMUSG00000046160(gene)|ensembl:ENSMUST00000056882(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q9JKN5|entrezgene/locuslink:50914(identity) ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2|entrezgene/locuslink:30046(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1R93ekMg/uZq5unF9PJGlf/iiJ810090 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rigid:LqkVoT8fg7MZrrylxVmOOaSR3cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKN5 uniprotkb:P48754 intact:EBI-1213712|ensembl:ENSMUSP00000061408 intact:EBI-6876136|ensembl:ENSMUSP00000017290|uniprotkb:A2A4Q4|uniprotkb:Q60957|uniprotkb:Q60983 psi-mi:olig1_mouse(display_long)|uniprotkb:Olig1(gene name)|psi-mi:Olig1(display_short)|uniprotkb:Oligodendrocyte-specific bHLH transcription factor 1(gene name synonym) psi-mi:brca1_mouse(display_long)|uniprotkb:Brca1(gene name)|psi-mi:Brca1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678528|imex:IM-28774-1213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058664.2|ensembl:ENSMUSG00000046160(gene)|ensembl:ENSMUST00000056882(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q9JKN5|entrezgene/locuslink:50914(identity) go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|reactome:R-MMU-3108214|ensembl:ENSMUSG00000017146(gene)|ensembl:ENSMUST00000017290(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|refseq:NP_033894.3|dip:DIP-41981N|entrezgene/locuslink:12189(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1R93ekMg/uZq5unF9PJGlf/iiJ810090 rogid:n930/noKAvHtITiW9/qUMSxbiT410090 rigid:qIB79Mx/a0OFuAgIC8eaXmOYDUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40424 uniprotkb:O14770 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678520|imex:IM-28774-3381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N|entrezgene/locuslink:4212(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 rigid:dJ6EXnnaZfAnBfTf/CztXr0mwpc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40424 uniprotkb:O00470 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369 psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678512|imex:IM-28774-2543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) refseq:NP_002389.1|ensembl:ENSG00000143995(gene)|ensembl:ENST00000272369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|entrezgene/locuslink:4211(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606 rigid:Lvw48sqCNrfAM2vCmSINimwxiks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40424 uniprotkb:O00470 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 intact:EBI-1210694|uniprotkb:A8MV50|ensembl:ENSP00000272369 psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:meis1_human(display_long)|uniprotkb:MEIS1(gene name)|psi-mi:MEIS1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678504|imex:IM-28774-725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) refseq:NP_002389.1|ensembl:ENSG00000143995(gene)|ensembl:ENST00000272369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:4XRS|rcsb pdb:5EGO|reactome:R-HSA-5617472|entrezgene/locuslink:4211(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rogid:X2N9fFxk9ZD7VQHf1oWkxJAtzsc9606 rigid:Lvw48sqCNrfAM2vCmSINimwxiks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99743 uniprotkb:O00327 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 intact:EBI-1794206|uniprotkb:O00313|uniprotkb:O00314|uniprotkb:O00315|uniprotkb:O00316|uniprotkb:O00317|uniprotkb:Q99631|uniprotkb:Q99649|uniprotkb:Q8IUT4|uniprotkb:D3DQW6|uniprotkb:A8K645|uniprotkb:B7WPG7|uniprotkb:B5ME11|uniprotkb:Q4G136|uniprotkb:A2I2N6|intact:EBI-28970920|ensembl:ENSP00000384517|ensembl:ENSP00000385581|ensembl:ENSP00000433571 psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:bmal1_human(display_long)|uniprotkb:ARNTL(gene name)|psi-mi:ARNTL(display_short)|uniprotkb:BMAL1(gene name synonym)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Member of PAS protein 3(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP3(gene name synonym)|uniprotkb:bHLH-PAS protein JAP3(gene name synonym)|uniprotkb:BHLHE5(gene name synonym)|uniprotkb:PASD3(gene name synonym)|uniprotkb:PAS domain-containing protein 3(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678496|imex:IM-28774-1635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) ensembl:ENST00000389707|ensembl:ENSP00000374357|ensembl:ENST00000401424|ensembl:ENSP00000385915|ensembl:ENSP00000384517|ensembl:ENST00000403482|ensembl:ENSP00000385897|ensembl:ENSP00000385581|ensembl:ENSP00000433571|refseq:XP_011518414.1|refseq:XP_011518415.1|refseq:NP_001025443.1|refseq:NP_001025444.1|refseq:NP_001169.3|refseq:XP_016873232.1|refseq:NP_001284648.1|refseq:NP_001284651.1|refseq:NP_001284653.1|refseq:XP_016873231.1|refseq:XP_016873235.1|refseq:XP_016873236.1|refseq:XP_016873237.1|dip:DIP-46008N|ensembl:ENSG00000133794(gene)|ensembl:ENST00000403290(transcript)|ensembl:ENST00000403510(transcript)|ensembl:ENST00000529388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4H10|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:406(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rogid:UJwUJQAcLUT6aEBNSUZOF6YyvMA9606 rigid:rtnAjgYTxSJuQ3rl1JIFA60UKxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99743 uniprotkb:O00327 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 intact:EBI-1794206|uniprotkb:O00313|uniprotkb:O00314|uniprotkb:O00315|uniprotkb:O00316|uniprotkb:O00317|uniprotkb:Q99631|uniprotkb:Q99649|uniprotkb:Q8IUT4|uniprotkb:D3DQW6|uniprotkb:A8K645|uniprotkb:B7WPG7|uniprotkb:B5ME11|uniprotkb:Q4G136|uniprotkb:A2I2N6|intact:EBI-28970920|ensembl:ENSP00000384517|ensembl:ENSP00000385581|ensembl:ENSP00000433571 psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:bmal1_human(display_long)|uniprotkb:ARNTL(gene name)|psi-mi:ARNTL(display_short)|uniprotkb:BMAL1(gene name synonym)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Member of PAS protein 3(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP3(gene name synonym)|uniprotkb:bHLH-PAS protein JAP3(gene name synonym)|uniprotkb:BHLHE5(gene name synonym)|uniprotkb:PASD3(gene name synonym)|uniprotkb:PAS domain-containing protein 3(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678488|imex:IM-28774-2541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) ensembl:ENST00000389707|ensembl:ENSP00000374357|ensembl:ENST00000401424|ensembl:ENSP00000385915|ensembl:ENSP00000384517|ensembl:ENST00000403482|ensembl:ENSP00000385897|ensembl:ENSP00000385581|ensembl:ENSP00000433571|refseq:XP_011518414.1|refseq:XP_011518415.1|refseq:NP_001025443.1|refseq:NP_001025444.1|refseq:NP_001169.3|refseq:XP_016873232.1|refseq:NP_001284648.1|refseq:NP_001284651.1|refseq:NP_001284653.1|refseq:XP_016873231.1|refseq:XP_016873235.1|refseq:XP_016873236.1|refseq:XP_016873237.1|dip:DIP-46008N|ensembl:ENSG00000133794(gene)|ensembl:ENST00000403290(transcript)|ensembl:ENST00000403510(transcript)|ensembl:ENST00000529388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4H10|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:406(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rogid:UJwUJQAcLUT6aEBNSUZOF6YyvMA9606 rigid:rtnAjgYTxSJuQ3rl1JIFA60UKxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75175 uniprotkb:Q9NZN8 intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867 intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260 psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym) psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678480|imex:IM-28774-1633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N|entrezgene/locuslink:4849(identity) refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F|entrezgene/locuslink:4848(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606 rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606 rigid:ECmiH/UBRW4Kb36JNdFHI94otE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75175 uniprotkb:Q9NZN8 intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867 intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260 psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym) psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678472|imex:IM-28774-2123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N|entrezgene/locuslink:4849(identity) refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F|entrezgene/locuslink:4848(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606 rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606 rigid:ECmiH/UBRW4Kb36JNdFHI94otE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZN8 uniprotkb:Q16531 intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678464|imex:IM-28774-2121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F|entrezgene/locuslink:4848(identity) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N|entrezgene/locuslink:1642(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:n2Q+XnpRJSKlBn809bHHHBQ/geE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HA7 uniprotkb:Q01844 intact:EBI-1052467|uniprotkb:Q13006|uniprotkb:Q9UGJ2|uniprotkb:B5MDP0|uniprotkb:C9JKB1|uniprotkb:C9JNV8|intact:EBI-28979102|ensembl:ENSP00000386239 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:tonsl_human(display_long)|uniprotkb:IKBR(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2(gene name synonym)|uniprotkb:Inhibitor of kappa B-related protein(gene name synonym)|uniprotkb:TONSL(gene name)|psi-mi:TONSL(display_short)|uniprotkb:NFKBIL2(gene name synonym)|uniprotkb:NF-kappa-B inhibitor-like protein 2(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678456|imex:IM-28774-723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038460.4|ensembl:ENSP00000386239|ensembl:ENSG00000160949(gene)|ensembl:ENST00000409379(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016604"(nuclear body)|go:"GO:0031297"(replication fork processing)|go:"GO:0042393"(histone binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR032675|interpro:IPR036770|mint:Q96HA7|rcsb pdb:5JA4|entrezgene/locuslink:4796(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Y06T7HJriv692FDbQzKyimJb6z09606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:mwpvbeJYT0XNTTb964RS1o2Zu9k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14494 uniprotkb:P51610 intact:EBI-2804436|intact:EBI-28976146|ensembl:ENSP00000354855|uniprotkb:Q96FN6|uniprotkb:Q12877|uniprotkb:D3DTU3|uniprotkb:D3DTU5 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:nf2l1_human(display_long)|uniprotkb:HBZ17(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:TCF11(gene name synonym)|uniprotkb:Locus control region-factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor 11(gene name synonym)|uniprotkb:NFE2L1(gene name)|psi-mi:NFE2L1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Protein NRF1, p120 form(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678448|imex:IM-28774-1211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000357480|ensembl:ENSP00000350072|ensembl:ENSP00000354855|ensembl:ENST00000585291|ensembl:ENSP00000461960|ensembl:ENSG00000082641(gene)|ensembl:ENST00000362042(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:1901329"(regulation of odontoblast differentiation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029847|refseq:NP_003195.1|refseq:XP_005257467.1|refseq:XP_005257469.1|refseq:NP_001317191.1|entrezgene/locuslink:4779(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|entrezgene/locuslink:3054(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/mXRFWPHxGFlrQmbhG3eDz9uXoc9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:Jrp4tQ2pbeSo1Bndi5Zxu/PdFhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16621 uniprotkb:P05114 intact:EBI-726369|uniprotkb:Q07720|uniprotkb:Q6ICV9|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:nfe2_human(display_long)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:NFE2(gene name)|psi-mi:NFE2(display_short) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678440|imex:IM-28774-3379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248390.1|refseq:NP_001129495.1|refseq:NP_006154.1|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558|refseq:XP_005268963.1|ensembl:ENSG00000123405(gene)|ensembl:ENST00000312156(transcript)|ensembl:ENST00000435572(transcript)|ensembl:ENST00000540264(transcript)|ensembl:ENST00000553070(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007599"(hemostasis)|go:"GO:0016605"(PML body)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|rcsb pdb:1LVX|rcsb pdb:2KZ5|reactome:R-HSA-8936459|reactome:R-HSA-983231|dip:DIP-57844N|entrezgene/locuslink:4778(identity) refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|entrezgene/locuslink:3150(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Y8uGUXDj1DbJnvZT2aZ5suX/yDE9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:ZDvVrs7kF1DS1RyXUo3f+8xkQUs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2Y9 uniprotkb:P61457 intact:EBI-1255893|uniprotkb:Q9Y356|ensembl:ENSP00000302456|ensembl:ENSP00000484904 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:klf13_human(display_long)|uniprotkb:KLF13(gene name)|psi-mi:KLF13(display_short)|uniprotkb:BTEB3(gene name synonym)|uniprotkb:NSLP1(gene name synonym)|uniprotkb:Transcription factor BTEB3(gene name synonym)|uniprotkb:Basic transcription element-binding protein 3(gene name synonym)|uniprotkb:RANTES factor of late activated T-lymphocytes 1(gene name synonym)|uniprotkb:Transcription factor NSLP1(gene name synonym)|uniprotkb:Novel Sp1-like zinc finger transcription factor 1(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678720|imex:IM-28774-1217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057079.2|refseq:NP_001289390.1|ensembl:ENSG00000169926(gene)|ensembl:ENSG00000275746(gene)|ensembl:ENST00000307145(transcript)|ensembl:ENST00000621843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y2Y9|entrezgene/locuslink:51621(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wNe/LpQEtkZiIwgsCk+owhIPUvk9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:7qIY0dd5kH6HFSb5QT88uGKJK5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HBM6 uniprotkb:O75177 intact:EBI-751601|uniprotkb:Q9Y2S3|uniprotkb:B2RUZ9|ensembl:ENSP00000339917 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:taf9b_human(display_long)|uniprotkb:Transcription initiation factor TFIID subunit 9-like(gene name synonym)|uniprotkb:Transcription-associated factor TAFII31L(gene name synonym)|uniprotkb:Neuronal cell death-related protein 7(gene name synonym)|uniprotkb:TAF9B(gene name)|psi-mi:TAF9B(display_short)|uniprotkb:TAF9L(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678712|imex:IM-28774-2971 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057059.2|ensembl:ENSG00000187325(gene)|ensembl:ENST00000341864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q9HBM6|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:51616(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8+i5lmcx4OcgCEbk2F9MS8bYhos9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:21UcifH1hiPZQUVjK5fR3+iIIqA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y603 uniprotkb:Q15306 intact:EBI-3919132|ensembl:ENSP00000341843|uniprotkb:Q9NZ65|uniprotkb:B4E1G4|uniprotkb:Q9NZR8|uniprotkb:B3KVC2|uniprotkb:Q9Y604|uniprotkb:Q9Y5K4|uniprotkb:Q5R3L4|uniprotkb:Q5R3L3|uniprotkb:Q9NZ68|uniprotkb:Q9NZ66|uniprotkb:Q9UNJ7|uniprotkb:B4DVB6 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 psi-mi:etv7_human(display_long)|uniprotkb:ETV7(gene name)|psi-mi:ETV7(display_short)|uniprotkb:TEL2(gene name synonym)|uniprotkb:TELB(gene name synonym)|uniprotkb:TREF(gene name synonym)|uniprotkb:ETS translocation variant 7(gene name synonym)|uniprotkb:ETS-related protein Tel2(gene name synonym)|uniprotkb:Tel-related Ets factor(gene name synonym)|uniprotkb:Transcription factor Tel-2(gene name synonym) psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678704|imex:IM-28774-2129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000010030(gene)|ensembl:ENST00000340181(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|refseq:NP_001193964.1|refseq:NP_001193965.1|refseq:NP_001193966.1|refseq:NP_001193967.1|refseq:NP_001193968.1|refseq:NP_001193969.1|refseq:NP_001193970.1|refseq:NP_057219.1|entrezgene/locuslink:51513(identity) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QxrIcD18vczcgAS9Zm6fmcWSOA89606 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rigid:o8sWTaZpojGOr6TqJDUtC9efG3g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IXH7 uniprotkb:Q9H3P2 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-5461341|uniprotkb:A2A2T1|uniprotkb:O95392|ensembl:ENSP00000372335 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:nelfa_human(display_long)|uniprotkb:NELFA(gene name)|psi-mi:NELFA(display_short)|uniprotkb:WHSC2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 2 protein(gene name synonym)|uniprotkb:P/OKcl.15(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678696|imex:IM-28774-1215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N|entrezgene/locuslink:51497(identity) refseq:NP_005654.3|dip:DIP-48478N|ensembl:ENSP00000372335|reactome:R-HSA-75955|ensembl:ENSG00000185049(gene)|ensembl:ENST00000382882(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR037517|mint:Q9H3P2|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|entrezgene/locuslink:7469(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:5p43n+2CBfrTYOtRcnBf13uqM0o9606 rigid:A1hQf+egnQbY+IBpbdBr8RmSDeM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99990 uniprotkb:Q99594 intact:EBI-11983165|ensembl:ENSP00000359668|uniprotkb:Q5H915 intact:EBI-746720|uniprotkb:O95910|uniprotkb:Q5BJG7|uniprotkb:Q8N6Y4|ensembl:ENSP00000345772 psi-mi:vgll1_human(display_long)|uniprotkb:VGLL1(gene name)|psi-mi:VGLL1(display_short)|uniprotkb:Protein TONDU(gene name synonym)|uniprotkb:TDU(gene name synonym) psi-mi:tead3_human(display_long)|uniprotkb:TEA domain family member 3(gene name synonym)|uniprotkb:DTEF-1(gene name synonym)|uniprotkb:TEAD3(gene name)|psi-mi:TEAD3(display_short)|uniprotkb:TEF5(gene name synonym)|uniprotkb:TEAD5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678688|imex:IM-28774-2127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102243(gene)|ensembl:ENST00000370634(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006627(Protein of unknown function TDU)|interpro:IPR011520(Vestigial/tondu)|refseq:NP_057351.1|entrezgene/locuslink:51442(identity) ensembl:ENSG00000007866(gene)|ensembl:ENST00000338863(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007565"(female pregnancy)|go:"GO:0035329"(hippo signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027253|interpro:IPR038096|interpro:IPR041086|rcsb pdb:5EMW|rcsb pdb:7CNL|reactome:R-HSA-2032785|reactome:R-HSA-8951671|refseq:NP_003205.2|dip:DIP-50657N|entrezgene/locuslink:7005(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QPFXNi2fpqwewIUjuh/MIOisTJk9606 rogid:mpZX/3rTg603Q9CzWum4fHXINow9606 rigid:pH/ZtuoYHJFddwzf7HprJRQf8T0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q3 uniprotkb:Q9UIJ5 intact:EBI-3649340|uniprotkb:B3KNE1|uniprotkb:Q9H1F1|ensembl:ENSP00000362410 intact:EBI-26466319|ensembl:ENSP00000262096|uniprotkb:D3DSP5 psi-mi:mafb_human(display_long)|uniprotkb:MAFB(gene name)|psi-mi:MAFB(display_short)|uniprotkb:KRML(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:zdhc2_human(display_long)|uniprotkb:ZDHHC2(gene name)|psi-mi:ZDHHC2(display_short)|uniprotkb:REAM(gene name synonym)|uniprotkb:REC(gene name synonym)|uniprotkb:ZNF372(gene name synonym)|uniprotkb:Acyltransferase ZDHHC2(gene name synonym)|uniprotkb:Reduced expression associated with metastasis protein(gene name synonym)|uniprotkb:Reduced expression in cancer protein(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger protein 372(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678664|imex:IM-28774-2551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005452.2|ensembl:ENSP00000362410|ensembl:ENSG00000204103(gene)|ensembl:ENST00000373313(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|mint:Q9Y5Q3|reactome:R-HSA-5617472|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007423"(sensory organ development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:9935(identity) ensembl:ENSG00000104219(gene)|ensembl:ENST00000262096(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019705"(protein-cysteine S-myristoyltransferase activity)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1905751"(positive regulation of endosome to plasma membrane protein transport)|interpro:IPR001594(Zinc finger, DHHC-type)|reactome:R-HSA-5683826|refseq:NP_057437.1|entrezgene/locuslink:51201(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0TC5DeljJqY/ClydzzdvMScyhzI9606 rogid:sboNX/lElOYDVB0KAyHbdi+E+z49606 rigid:rM4SBMcEsorvaEzbdKIw1Yg06L0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16633 uniprotkb:P23769 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678832|imex:IM-28774-1651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|entrezgene/locuslink:2624(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 rigid:6I7NshIptxnqWCJOxn/Bor1Gako false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19388 uniprotkb:P29590 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678824|imex:IM-28774-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N|entrezgene/locuslink:5434(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:QbkEbI6s6NReknrvLTSfm/6oszw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15514 uniprotkb:P31274 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678816|imex:IM-28774-2131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N|entrezgene/locuslink:5433(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:F6wkIgO02Yc3MUlZQ2h2pRSI/XM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15514 uniprotkb:Q04741 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678808|imex:IM-28774-2975 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N|entrezgene/locuslink:5433(identity) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rigid:/tWAF1oPOmEX7fcCty2AWsozVos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70434 uniprotkb:P09632 intact:EBI-997907|ensembl:ENSMUSP00000026571 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:irf7_mouse(display_long)|uniprotkb:Irf7(gene name)|psi-mi:Irf7(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678800|imex:IM-28774-735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058546.1|reactome:R-MMU-975110|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QU3|reactome:R-MMU-3134963|reactome:R-MMU-9013973|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-936964|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|ensembl:ENSMUST00000026571(transcript)|ensembl:ENSMUSG00000025498(gene)|dip:DIP-37903N|entrezgene/locuslink:54123(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AWh1RBKJClvTwKD67SGzcTM4aH410090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:7SjwpUo30hY7j/ut5tkLCjAzJE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70434 uniprotkb:Q04742 intact:EBI-997907|ensembl:ENSMUSP00000026571 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:irf7_mouse(display_long)|uniprotkb:Irf7(gene name)|psi-mi:Irf7(display_short) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678792|imex:IM-28774-733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058546.1|reactome:R-MMU-975110|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QU3|reactome:R-MMU-3134963|reactome:R-MMU-9013973|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-936964|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|ensembl:ENSMUST00000026571(transcript)|ensembl:ENSMUSG00000025498(gene)|dip:DIP-37903N|entrezgene/locuslink:54123(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:AWh1RBKJClvTwKD67SGzcTM4aH410090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:xtDel8tYlmEdNmG16g2ZSOMxp5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UMX1 uniprotkb:P08151 intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name) psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678728|imex:IM-28774-729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|entrezgene/locuslink:51684(identity) refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N|entrezgene/locuslink:2735(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 rigid:JOx0hhBN9wqKAGpAFIWK1s6MlbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:P29590 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678768|imex:IM-28774-1649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:i432ZKrVM1/1ZblD151kGyMPQN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q922V4 uniprotkb:Q07279 intact:EBI-8339071|uniprotkb:O55039|intact:MINT-4107987|ensembl:ENSMUSP00000114968 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:plrg1_mouse(display_long)|uniprotkb:Plrg1(gene name)|psi-mi:Plrg1(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678760|imex:IM-28774-2973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058064.2|ensembl:ENSMUSG00000027998(gene)|ensembl:ENSMUST00000150268(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q922V4|reactome:R-MMU-72163|entrezgene/locuslink:53317(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - function:Necessary for spliceosome assembly and for pre-mRNA splicing|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:h7ILw7JCfPhjX2tdlQhnVjhpq9U10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:KoOWW4RxA8pVz0y8iBuxNna4Me4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35284 uniprotkb:P09450 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-5347760|uniprotkb:Q8C2G9|ensembl:ENSMUSP00000064680 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:junb_mouse(display_long)|uniprotkb:Junb(gene name)|psi-mi:Junb(display_short)|uniprotkb:Jun-b(gene name synonym)|uniprotkb:MyD21(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678752|imex:IM-28774-731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1|entrezgene/locuslink:53314(identity) dip:DIP-1069N|refseq:NP_032442.1|ensembl:ENSMUSG00000052837(gene)|ensembl:ENSMUST00000064922(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009987"(cellular process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|entrezgene/locuslink:16477(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 rogid:jnlW1k7KFty2J0v0PVptgt0oWVo10090 rigid:1MW1SPc1X1CIB4IrP+p/+J5IwkM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55347 uniprotkb:P40424 intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym) psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678744|imex:IM-28774-1219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472|entrezgene/locuslink:5316(identity) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rigid:S1ILjdgxUiF2wzEvDEJHR52z+/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55347 uniprotkb:P40424 intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym) psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678736|imex:IM-28774-1647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472|entrezgene/locuslink:5316(identity) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rigid:S1ILjdgxUiF2wzEvDEJHR52z+/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29590 uniprotkb:P29590 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678776|imex:IM-28774-1221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:a5R5U23lPrYFmE39dofzUG8f9/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37231 uniprotkb:P29590 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678960|imex:IM-28774-1225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:GvFA73N0/lulx6lfa+9lh+Eu85I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16633 uniprotkb:P32780 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678840|imex:IM-28774-3387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N|entrezgene/locuslink:2965(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:qjZx/wIp7V2BrME62TzpyoD/T0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PCT2 uniprotkb:O43439 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678944|imex:IM-28774-1659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2|entrezgene/locuslink:54620(identity) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rigid:dfdjAKGoWD9R94y4aN5WPXuki1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PCT2 uniprotkb:P14373 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678936|imex:IM-28774-741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2|entrezgene/locuslink:54620(identity) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rigid:mmsoeQvPGcyJIdi7if+31HVHJh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PCT2 uniprotkb:Q14134 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678928|imex:IM-28774-3391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2|entrezgene/locuslink:54620(identity) refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300|entrezgene/locuslink:23650(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rigid:y+Rfnus7q2MdXxXimIhv0SFSr6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09086 uniprotkb:Q16633 intact:EBI-11317725|uniprotkb:Q9BRS4|uniprotkb:Q7M4M8|uniprotkb:Q16648|intact:EBI-28988826|ensembl:ENSP00000431603 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 psi-mi:po2f2_human(display_long)|uniprotkb:Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2(gene name synonym)|uniprotkb:OCT2(gene name synonym)|uniprotkb:OTF2(gene name synonym)|uniprotkb:Octamer-binding protein 2(gene name synonym)|uniprotkb:Octamer-binding transcription factor 2(gene name synonym)|uniprotkb:POU2F2(gene name)|psi-mi:POU2F2(display_short) psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678920|imex:IM-28774-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193954.1|refseq:NP_001193955.1|refseq:NP_001234923.1|refseq:NP_002689.1|ensembl:ENST00000389341|ensembl:ENSP00000373992|ensembl:ENSP00000431603|ensembl:ENST00000529067|ensembl:ENSP00000437224|ensembl:ENST00000529952|ensembl:ENSP00000436988|ensembl:ENSG00000028277(gene)|ensembl:ENST00000526816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|rcsb pdb:1HDP|reactome:R-HSA-6807505|dip:DIP-51N|entrezgene/locuslink:5452(identity) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZkxrWf3T001epln3FYwEHWSXXTE9606 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rigid:T7RQhsiyxvpiVVvZSRlo5ZTfL/U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14859 uniprotkb:P14859 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678904|imex:IM-28774-1657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rigid:IFP0zCUBpu8MmMdxEh9J9h0awM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14859 uniprotkb:Q16633 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678896|imex:IM-28774-1655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rigid:jQal3oGBSqWIeXSwp8DDe1uT5zQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14859 uniprotkb:P31274 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678888|imex:IM-28774-1223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:vi7qESckucFll1R3IcW7HBt4uTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14859 uniprotkb:O43763 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678880|imex:IM-28774-2977 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:3vsmSR/5aRYJ3de2m4RX+HUgDNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14859 uniprotkb:Q15744 intact:EBI-624770|uniprotkb:Q5TBT7|uniprotkb:Q6PK46|uniprotkb:Q8NEU9|uniprotkb:Q9BPV1|intact:EBI-28988911|ensembl:ENSP00000441285|uniprotkb:B1AL91|uniprotkb:B1AL93|uniprotkb:B4E029|uniprotkb:J3KP77 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:po2f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:NF-A1(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678872|imex:IM-28774-1653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143190(gene)|ensembl:ENST00000541643(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|reactome:R-HSA-9018519|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|mint:P14859|rcsb pdb:1CQT|rcsb pdb:1E3O|rcsb pdb:1GT0|rcsb pdb:1HF0|rcsb pdb:1O4X|rcsb pdb:1OCT|rcsb pdb:1POG|rcsb pdb:1POU|reactome:R-HSA-6785807|refseq:NP_001185715.1|refseq:NP_001185712.1|refseq:NP_002688.3|ensembl:ENST00000367862|ensembl:ENSP00000356836|ensembl:ENST00000367866|ensembl:ENSP00000356840|ensembl:ENST00000429375|ensembl:ENSP00000401217|ensembl:ENSP00000441285|refseq:XP_011507956.1|dip:DIP-226N|entrezgene/locuslink:5451(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:znBO7MSmTt52C2Lr6il25Hb9OBc9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:GLnCsiCPUqHXbUn1ToSL3FEMmTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16633 uniprotkb:Q13506 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 intact:EBI-2863712|uniprotkb:Q9UEV1|uniprotkb:O75384|uniprotkb:Q6GTU1|uniprotkb:O75383|ensembl:ENSP00000336894|ensembl:ENSP00000387089 psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:nab1_human(display_long)|uniprotkb:NAB1(gene name)|psi-mi:NAB1(display_short)|uniprotkb:EGR-1-binding protein 1(gene name synonym)|uniprotkb:Transcriptional regulatory protein p54(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678864|imex:IM-28774-2553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) refseq:XP_011509521.1|refseq:NP_005957.2|refseq:XP_016859659.1|refseq:XP_016859665.1|refseq:XP_005246639.1|refseq:XP_005246640.1|refseq:NP_001308241.1|refseq:NP_001308242.1|refseq:NP_001308243.1|refseq:NP_001308244.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0042552"(myelination)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR006986(Nab1, C-terminal)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR006989(Nab, central region)|interpro:IPR038398|interpro:IPR039040|rcsb pdb:2YUF|reactome:R-HSA-9031628|reactome:R-HSA-9619665|ensembl:ENSG00000138386(gene)|ensembl:ENST00000337386(transcript)|ensembl:ENST00000409581(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|entrezgene/locuslink:4664(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rogid:NfG5F48HahujhxoiPrOOURhtBn89606 rigid:MTGXlu9RAAhsm+Y9HrO7OpqjHGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35548 uniprotkb:Q16633 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678856|imex:IM-28774-737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rigid:1X/sEcVfl3ElVz+zEHhRlLnnD68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16633 uniprotkb:Q15796 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678848|imex:IM-28774-3389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N|entrezgene/locuslink:4087(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:jcoXmJKdNCeGcphgFYRqIvTk+xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35548 uniprotkb:P37231 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678952|imex:IM-28774-2555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:E0gfbY1EqD1IllV9ZEYeTjuKx4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43593 uniprotkb:O60907 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-3505105|uniprotkb:A8K044|uniprotkb:A8K4J7|uniprotkb:Q86UY2|ensembl:ENSP00000385988|ensembl:ENSP00000493782|ensembl:ENSP00000495556|ensembl:ENSP00000496215 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:tbl1x_human(display_long)|uniprotkb:TBL1X(gene name)|psi-mi:TBL1X(display_short)|uniprotkb:TBL1(gene name synonym)|uniprotkb:SMAP55(gene name synonym)|uniprotkb:Transducin beta-like protein 1X(gene name synonym)|uniprotkb:Transducin-beta-like protein 1, X-linked(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679208|imex:IM-28774-1239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2|entrezgene/locuslink:55806(identity) refseq:XP_011543873.1|refseq:NP_001132938.1|refseq:NP_001132939.1|refseq:NP_001132940.1|refseq:NP_005638.1|ensembl:ENSG00000101849(gene)|ensembl:ENST00000407597(transcript)|ensembl:ENST00000645353(transcript)|ensembl:ENST00000645686(transcript)|ensembl:ENST00000646640(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006508"(proteolysis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2XTC|rcsb pdb:2XTD|rcsb pdb:2XTE|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|dip:DIP-60532N|entrezgene/locuslink:6907(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:SQV81eLzdxXuG1b7Kof8190KyyU9606 rigid:iVb+sJxeJFdSL9nmtfb4kXdwd1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TAP4 uniprotkb:Q86U70 intact:EBI-742259|uniprotkb:Q58A66|uniprotkb:Q8N974|uniprotkb:Q9UDD5|ensembl:ENSP00000312856|ensembl:ENSP00000346689|ensembl:ENSP00000412479|ensembl:ENSP00000413703|ensembl:ENSP00000439275|ensembl:ENSP00000440099|ensembl:ENSP00000444393|ensembl:ENSP00000445751|ensembl:ENSP00000446115|uniprotkb:B4DH35|uniprotkb:Q58A67|uniprotkb:B4DG90 intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277 psi-mi:lmo3_human(display_long)|uniprotkb:LMO3(gene name)|psi-mi:LMO3(display_short)|uniprotkb:RBTN3(gene name synonym)|uniprotkb:RHOM3(gene name synonym)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Rhombotin-3(gene name synonym)|uniprotkb:RBTNL2(gene name synonym) psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679216|imex:IM-28774-2993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001395.1|refseq:NP_001230538.1|refseq:NP_001230539.1|refseq:NP_061110.2|refseq:NP_001230540.1|ensembl:ENSG00000048540(gene)|ensembl:ENST00000320122(transcript)|ensembl:ENST00000354662(transcript)|ensembl:ENST00000441439(transcript)|ensembl:ENST00000447609(transcript)|ensembl:ENST00000534946(transcript)|ensembl:ENST00000535535(transcript)|ensembl:ENST00000537304(transcript)|ensembl:ENST00000540848(transcript)|ensembl:ENST00000541846(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:XP_011519064.1|refseq:XP_011519065.1|refseq:NP_001230542.1|refseq:NP_001230541.1|refseq:XP_006719173.1|refseq:XP_006719174.1|dip:DIP-50129N|entrezgene/locuslink:55885(identity) refseq:NP_001106878.1|refseq:NP_003884.1|dip:DIP-31826N|ensembl:ENSG00000198728(gene)|ensembl:ENST00000673968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|reactome:R-HSA-8939236|reactome:R-HSA-9010553|entrezgene/locuslink:8861(identity) - crc64:05284546BA5EC226 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc9606 rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606 rigid:/yHecLOV8qOkUmn2mzDwDyqVkt0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43593 uniprotkb:P10826 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-2568838|uniprotkb:P12891|uniprotkb:Q00989|uniprotkb:Q15298|uniprotkb:Q9UN48 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:rarb_human(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679192|imex:IM-28774-3395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2|entrezgene/locuslink:55806(identity) refseq:NP_000956.2|refseq:NP_057236.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0007165"(signal transduction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1HRA|rcsb pdb:1XAP|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:5UAN|rcsb pdb:6SSQ|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-5617472|refseq:NP_001277195.1|refseq:NP_001277205.1|refseq:NP_001277145.1|refseq:NP_001277146.1|interpro:IPR035500|mint:P10826|entrezgene/locuslink:5915(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:GviMMhEdTqNBuvQ8p2XTKxllgdc9606 rigid:fwa1NHche/s+qdVNwmpJCYLkV4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43593 uniprotkb:P10276 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679184|imex:IM-28774-2991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2|entrezgene/locuslink:55806(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|entrezgene/locuslink:5914(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rigid:u9d3jCSha6o05v4BSX1S2g8pIsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q3 uniprotkb:Q9NTW7 intact:EBI-3649340|uniprotkb:B3KNE1|uniprotkb:Q9H1F1|ensembl:ENSP00000362410 intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5 psi-mi:mafb_human(display_long)|uniprotkb:MAFB(gene name)|psi-mi:MAFB(display_short)|uniprotkb:KRML(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679176|imex:IM-28774-1663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005452.2|ensembl:ENSP00000362410|ensembl:ENSG00000204103(gene)|ensembl:ENST00000373313(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|mint:Q9Y5Q3|reactome:R-HSA-5617472|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007423"(sensory organ development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:9935(identity) refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0TC5DeljJqY/ClydzzdvMScyhzI9606 rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606 rigid:qDILNjeAEPwL1R7ytq1V2JqmLt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NTW7 uniprotkb:Q9UC06 intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5 intact:EBI-21635972|ensembl:ENSP00000339314 psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym) psi-mi:znf70_human(display_long)|uniprotkb:Zinc finger protein N27C7-1(gene name synonym)|uniprotkb:ZNF70(gene name)|psi-mi:ZNF70(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679168|imex:IM-28774-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity) refseq:NP_068735.1|ensembl:ENST00000341976(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000187792(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:7621(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606 rogid:DfftPhN/eQ5zvb0Srf3O2Rgrfh09606 rigid:+VYfB+x29lhGQZtLd6Y6SEWO70E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:Q5TD97 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679160|imex:IM-28774-2989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606 rigid:77JEjIrDyhF7ja8tASYXlXPmNYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:Q9UNY5 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-749023|ensembl:ENSP00000250076 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:zn232_human(display_long)|uniprotkb:Zinc finger and SCAN domain-containing protein 11(gene name synonym)|uniprotkb:ZNF232(gene name)|psi-mi:ZNF232(display_short)|uniprotkb:ZSCAN11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679152|imex:IM-28774-1235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_055334.2|refseq:NP_001307882.1|refseq:NP_001307883.1|ensembl:ENSG00000167840(gene)|ensembl:ENST00000250076(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016880510.1|entrezgene/locuslink:7775(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:18jIzxhG0JCfrQpWx8F7FkmYnQ09606 rigid:nr2yMNIEcWST++ZENwpg59QckGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:Q9UNY5 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-749023|ensembl:ENSP00000250076 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:zn232_human(display_long)|uniprotkb:Zinc finger and SCAN domain-containing protein 11(gene name synonym)|uniprotkb:ZNF232(gene name)|psi-mi:ZNF232(display_short)|uniprotkb:ZSCAN11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679144|imex:IM-28774-753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_055334.2|refseq:NP_001307882.1|refseq:NP_001307883.1|ensembl:ENSG00000167840(gene)|ensembl:ENST00000250076(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016880510.1|entrezgene/locuslink:7775(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:18jIzxhG0JCfrQpWx8F7FkmYnQ09606 rigid:nr2yMNIEcWST++ZENwpg59QckGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:O15535 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-751531|uniprotkb:Q2TTR1|uniprotkb:B4E1W6|uniprotkb:E7EVQ2|ensembl:ENSP00000252207|ensembl:ENSP00000433402 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:zsc9_human(display_long)|uniprotkb:ZSCAN9(gene name)|psi-mi:ZSCAN9(display_short)|uniprotkb:Cell proliferation-inducing gene 12 protein(gene name synonym)|uniprotkb:PRD51(gene name synonym)|uniprotkb:ZNF193(gene name synonym)|uniprotkb:Zinc finger protein 193(gene name synonym)|uniprotkb:PIG12(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679136|imex:IM-28774-2987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_001186409.1|refseq:NP_006290.1|refseq:NP_001186408.1|refseq:XP_016866756.1|ensembl:ENSG00000137185(gene)|ensembl:ENST00000252207(transcript)|ensembl:ENST00000531979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:O15535|entrezgene/locuslink:7746(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:NpEnjqbpSwof7YWBbMvQlSvkdeM9606 rigid:Xol8/qX8nExOe3RgtjkBK1o7cSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:O15535 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-751531|uniprotkb:Q2TTR1|uniprotkb:B4E1W6|uniprotkb:E7EVQ2|ensembl:ENSP00000252207|ensembl:ENSP00000433402 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:zsc9_human(display_long)|uniprotkb:ZSCAN9(gene name)|psi-mi:ZSCAN9(display_short)|uniprotkb:Cell proliferation-inducing gene 12 protein(gene name synonym)|uniprotkb:PRD51(gene name synonym)|uniprotkb:ZNF193(gene name synonym)|uniprotkb:Zinc finger protein 193(gene name synonym)|uniprotkb:PIG12(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679128|imex:IM-28774-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_001186409.1|refseq:NP_006290.1|refseq:NP_001186408.1|refseq:XP_016866756.1|ensembl:ENSG00000137185(gene)|ensembl:ENST00000252207(transcript)|ensembl:ENST00000531979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:O15535|entrezgene/locuslink:7746(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:NpEnjqbpSwof7YWBbMvQlSvkdeM9606 rigid:Xol8/qX8nExOe3RgtjkBK1o7cSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:P17028 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679120|imex:IM-28774-2135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|entrezgene/locuslink:7572(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rigid:OrjhjaaYZwGsk5o1dd5VCNOZX8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWS9 uniprotkb:P17028 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679112|imex:IM-28774-751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|entrezgene/locuslink:7572(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rigid:OrjhjaaYZwGsk5o1dd5VCNOZX8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C0G0 uniprotkb:P42226 intact:EBI-5654914|uniprotkb:Q9H8A1|uniprotkb:Q96MY0|uniprotkb:B5MD54|uniprotkb:Q9NXD7|uniprotkb:Q9NXD4|ensembl:ENSP00000299687 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:zn407_human(display_long)|uniprotkb:KIAA1703(gene name synonym)|uniprotkb:ZNF407(gene name)|psi-mi:ZNF407(display_short) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679104|imex:IM-28774-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524372.1|refseq:XP_011524370.1|refseq:NP_001139661.1|refseq:NP_001139662.1|refseq:NP_060227.2|refseq:XP_005266783.1|ensembl:ENSG00000215421(gene)|ensembl:ENST00000299687(transcript)|interpro:IPR036236|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:55628(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1IwRCT+v3qYg2Ii3jabVzznKu8Y9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:BmHIOt233dN4gtptKssKE1a9udM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JK9 uniprotkb:O00267 intact:EBI-1043855|intact:EBI-28973985|ensembl:ENSP00000421180|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679096|imex:IM-28774-2985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000421180|refseq:NP_061187.2|ensembl:ENSG00000196782(gene)|ensembl:ENST00000509479(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0016607"(nuclear speck)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|entrezgene/locuslink:55534(identity) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:FBSL3YjZeCsD0p6Z/7s1GJLvhJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JK9 uniprotkb:Q12986 intact:EBI-1043855|intact:EBI-28973985|ensembl:ENSP00000421180|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8 intact:EBI-2130062|uniprotkb:A8K6H8|uniprotkb:Q5VXW6|uniprotkb:Q96EL5|uniprotkb:Q9BXI1|ensembl:ENSP00000368856 psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym) psi-mi:nfx1_human(display_long)|uniprotkb:NFX1(gene name)|psi-mi:NFX1(display_short)|uniprotkb:NFX2(gene name synonym)|uniprotkb:Nuclear transcription factor, X box-binding protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679088|imex:IM-28774-1233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000421180|refseq:NP_061187.2|ensembl:ENSG00000196782(gene)|ensembl:ENST00000509479(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0016607"(nuclear speck)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|entrezgene/locuslink:55534(identity) refseq:NP_002495.2|refseq:NP_667345.1|ensembl:ENSG00000086102(gene)|ensembl:ENST00000379540(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR019787|interpro:IPR034076|interpro:IPR034078|interpro:IPR036867|entrezgene/locuslink:4799(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606 rogid:dMmLO5K0QbIay4rS9dqMKgJJUbg9606 rigid:rlkbNz0VbRx7h5g0Kvt4XU739oQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JK9 uniprotkb:Q8IYH5 intact:EBI-1043855|intact:EBI-28973985|ensembl:ENSP00000421180|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679080|imex:IM-28774-2133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000421180|refseq:NP_061187.2|ensembl:ENSG00000196782(gene)|ensembl:ENST00000509479(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0016607"(nuclear speck)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|entrezgene/locuslink:55534(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:uZeLTZ8L8X5/d7SxuuUAjHx9BmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JK9 uniprotkb:Q96GD3 intact:EBI-1043855|intact:EBI-28973985|ensembl:ENSP00000421180|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym) psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679072|imex:IM-28774-1231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000421180|refseq:NP_061187.2|ensembl:ENSG00000196782(gene)|ensembl:ENST00000509479(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0016607"(nuclear speck)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|entrezgene/locuslink:55534(identity) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1|entrezgene/locuslink:22955(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rigid:gsW9zE2sYanw4L178rfpn47ywcI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JK9 uniprotkb:Q9Y2K1 intact:EBI-1043855|intact:EBI-28973985|ensembl:ENSP00000421180|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8 intact:EBI-2682961|uniprotkb:Q86SW8|uniprotkb:A8K6S8|ensembl:ENSP00000451000|ensembl:ENSP00000506911 psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym) psi-mi:zbtb1_human(display_long)|uniprotkb:KIAA0997(gene name synonym)|uniprotkb:ZBTB1(gene name)|psi-mi:ZBTB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679064|imex:IM-28774-2983 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000421180|refseq:NP_061187.2|ensembl:ENSG00000196782(gene)|ensembl:ENST00000509479(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0016607"(nuclear speck)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|entrezgene/locuslink:55534(identity) refseq:XP_011534868.1|refseq:XP_011534870.1|refseq:XP_005267467.1|refseq:NP_001116801.1|refseq:NP_055765.2|refseq:XP_016876583.1|refseq:XP_016876584.1|ensembl:ENSG00000126804(gene)|ensembl:ENST00000554015(transcript)|ensembl:ENST00000683701(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002711"(positive regulation of T cell mediated immunity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048538"(thymus development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000176"(positive regulation of pro-T cell differentiation)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|entrezgene/locuslink:22890(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606 rogid:63ZwzhNK0fJBMGUMPfeRJnGqrcE9606 rigid:59/ovBwoIcMTAXknwu0zvQV/uNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JK9 uniprotkb:Q7Z5J4 intact:EBI-1043855|intact:EBI-28973985|ensembl:ENSP00000421180|uniprotkb:B2RNU9|uniprotkb:B3KVV7|uniprotkb:E7EVW8 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 psi-mi:maml3_human(display_long)|uniprotkb:MAML3(gene name)|psi-mi:MAML3(display_short)|uniprotkb:KIAA1816(gene name synonym) psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679056|imex:IM-28774-3393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000421180|refseq:NP_061187.2|ensembl:ENSG00000196782(gene)|ensembl:ENST00000509479(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0016607"(nuclear speck)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019082|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|entrezgene/locuslink:55534(identity) refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:10743(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6i+Dc9Y+mL9UVF/Du2ooTKwbPjo9606 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 rigid:8H2TUgj0mcMUYZldSG6Ag2pVNiA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NR55 uniprotkb:P18847 intact:EBI-10312707|ensembl:ENSP00000243440 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:batf3_human(display_long)|uniprotkb:BATF3(gene name)|psi-mi:BATF3(display_short)|uniprotkb:21 kDa small nuclear factor isolated from T-cells(gene name synonym)|uniprotkb:Jun dimerization protein p21SNFT(gene name synonym)|uniprotkb:SNFT(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679048|imex:IM-28774-749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061134.1|ensembl:ENSG00000123685(gene)|ensembl:ENST00000243440(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029818|entrezgene/locuslink:55509(identity) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N|entrezgene/locuslink:467(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hAyP6YHxONSUFMehlesRDi+E0z49606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rigid:3XymTgn4WuPY5vopCJJuExuCXhg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NR55 uniprotkb:P17275 intact:EBI-10312707|ensembl:ENSP00000243440 intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315 psi-mi:batf3_human(display_long)|uniprotkb:BATF3(gene name)|psi-mi:BATF3(display_short)|uniprotkb:21 kDa small nuclear factor isolated from T-cells(gene name synonym)|uniprotkb:Jun dimerization protein p21SNFT(gene name synonym)|uniprotkb:SNFT(gene name synonym) psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679040|imex:IM-28774-2981 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061134.1|ensembl:ENSG00000123685(gene)|ensembl:ENST00000243440(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029818|entrezgene/locuslink:55509(identity) refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N|entrezgene/locuslink:3726(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hAyP6YHxONSUFMehlesRDi+E0z49606 rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606 rigid:L3C39pJiomMc9vYWxb5KSzA4Jiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NR55 uniprotkb:P35638 intact:EBI-10312707|ensembl:ENSP00000243440 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:batf3_human(display_long)|uniprotkb:BATF3(gene name)|psi-mi:BATF3(display_short)|uniprotkb:21 kDa small nuclear factor isolated from T-cells(gene name synonym)|uniprotkb:Jun dimerization protein p21SNFT(gene name synonym)|uniprotkb:SNFT(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679032|imex:IM-28774-1661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061134.1|ensembl:ENSG00000123685(gene)|ensembl:ENST00000243440(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029818|entrezgene/locuslink:55509(identity) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) - - crc64:31905293FB1FBBE2 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hAyP6YHxONSUFMehlesRDi+E0z49606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:L4HFI1rpkxZ7x4KlX5AQ2H5jER4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HZ4 uniprotkb:Q04724 intact:EBI-7469266|intact:MINT-8313354|uniprotkb:Q9P2S3|uniprotkb:Q8N2J2|uniprotkb:Q96T93|uniprotkb:A8KAP6|uniprotkb:Q53SN9|uniprotkb:B8ZZA9|ensembl:ENSP00000272937 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:hes6_human(display_long)|uniprotkb:HES6(gene name)|psi-mi:HES6(display_short)|uniprotkb:BHLHB41(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 41(gene name synonym)|uniprotkb:Hairy and enhancer of split 6(gene name synonym)|uniprotkb:C-HAIRY1(gene name synonym) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679024|imex:IM-28774-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061115.2|refseq:NP_001136325.1|refseq:NP_001269363.1|ensembl:ENSG00000144485(gene)|ensembl:ENST00000272937(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|entrezgene/locuslink:55502(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wlV9updKrMm547AnAJ1V6Lgj/Kg9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:PVTgRseSzByBbiOzna9VvVU7SpM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P0N0 uniprotkb:P61457 intact:EBI-9870821|uniprotkb:D3DSA7|uniprotkb:Q86V14|uniprotkb:Q96PY4|uniprotkb:Q9NUR5|uniprotkb:Q9Y4X9|ensembl:ENSP00000309790 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:m18bp_human(display_long)|uniprotkb:MIS18BP1(gene name)|psi-mi:MIS18BP1(display_short)|uniprotkb:C14orf106(gene name synonym)|uniprotkb:KIAA1903(gene name synonym)|uniprotkb:KNL2(gene name synonym)|uniprotkb:M18BP1(gene name synonym)|uniprotkb:Kinetochore-associated protein KNL-2 homolog(gene name synonym)|uniprotkb:P243(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679016|imex:IM-28774-747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060823.3|refseq:XP_005267890.1|refseq:XP_016876914.1|ensembl:ENSG00000129534(gene)|ensembl:ENST00000310806(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015216(SANT associated)|interpro:IPR017884|interpro:IPR017930|interpro:IPR039110|rcsb pdb:1WGX|reactome:R-HSA-606279|entrezgene/locuslink:55320(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/2olIhyXaHJDtS5Yrj3zI8I/d+09606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:iqJsnpfM6Mplmlpi09q2p+G9g2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H8Y5 uniprotkb:P42226 intact:EBI-724848|uniprotkb:Q9NVZ4|intact:EBI-28979360|ensembl:ENSP00000321617|ensembl:ENSP00000386337 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:ankz1_human(display_long)|uniprotkb:Zinc finger protein 744(gene name synonym)|uniprotkb:ANKZF1(gene name)|psi-mi:ANKZF1(display_short)|uniprotkb:ZNF744(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679008|imex:IM-28774-745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035869.1|refseq:NP_060559.2|ensembl:ENSP00000321617|ensembl:ENSP00000386337|ensembl:ENSG00000163516(gene)|ensembl:ENST00000323348(transcript)|ensembl:ENST00000410034(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR002110(Ankyrin)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036770|interpro:IPR041175|interpro:IPR041540|entrezgene/locuslink:55139(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ddIMBu8TTSoqw3EFEPgqx+F0BHA9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:qGAqbOnXTOfcvszSIJ6e+ZsJBv8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NX65 uniprotkb:Q15697 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 intact:EBI-1210452|uniprotkb:Q9BQ34|uniprotkb:Q53Y68|ensembl:ENSP00000268655|ensembl:ENSP00000460397 psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:zn174_human(display_long)|uniprotkb:ZNF174(gene name)|psi-mi:ZNF174(display_short)|uniprotkb:ZSCAN8(gene name synonym)|uniprotkb:AW-1(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679000|imex:IM-28774-1229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1|entrezgene/locuslink:54925(identity) refseq:NP_001027463.1|refseq:NP_003441.1|refseq:NP_001334797.1|interpro:IPR038269|rcsb pdb:1Y7Q|ensembl:ENSG00000103343(gene)|ensembl:ENST00000268655(transcript)|ensembl:ENST00000571936(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027778|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|entrezgene/locuslink:7727(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 rogid:OotqJnbHr1LkdIoAnKfK0GrXhKo9606 rigid:t6QWf37cgzJpvcTwQeJkXiokun4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NX65 uniprotkb:Q15697 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 intact:EBI-1210452|uniprotkb:Q9BQ34|uniprotkb:Q53Y68|ensembl:ENSP00000268655|ensembl:ENSP00000460397 psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:zn174_human(display_long)|uniprotkb:ZNF174(gene name)|psi-mi:ZNF174(display_short)|uniprotkb:ZSCAN8(gene name synonym)|uniprotkb:AW-1(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678992|imex:IM-28774-1227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1|entrezgene/locuslink:54925(identity) refseq:NP_001027463.1|refseq:NP_003441.1|refseq:NP_001334797.1|interpro:IPR038269|rcsb pdb:1Y7Q|ensembl:ENSG00000103343(gene)|ensembl:ENST00000268655(transcript)|ensembl:ENST00000571936(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027778|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|entrezgene/locuslink:7727(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 rogid:OotqJnbHr1LkdIoAnKfK0GrXhKo9606 rigid:t6QWf37cgzJpvcTwQeJkXiokun4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NX65 uniprotkb:Q9NX65 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678976|imex:IM-28774-2979 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1|entrezgene/locuslink:54925(identity) refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1|entrezgene/locuslink:54925(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 rigid:OiwE8Do4oIHfmPM8lePuc4yf2Dg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NX65 uniprotkb:P57086 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 intact:EBI-745846|uniprotkb:Q6IAG7|ensembl:ENSP00000301995|ensembl:ENSP00000363103|ensembl:ENSP00000481289 psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:scnd1_human(display_long)|uniprotkb:SCAND1(gene name)|psi-mi:SCAND1(display_short)|uniprotkb:SDP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26678968|imex:IM-28774-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1|entrezgene/locuslink:54925(identity) refseq:NP_057642.1|ensembl:ENSG00000171222(gene)|ensembl:ENST00000305978(transcript)|ensembl:ENST00000373991(transcript)|ensembl:ENST00000615116(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269|refseq:NP_361012.2|entrezgene/locuslink:51282(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 rogid:PYwugMdd/3klI5aAelQle8pGoMQ9606 rigid:wfOw0HNXs0JmElLgUA0b4psfUNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JHE6 uniprotkb:P03966 intact:EBI-26679232|ensembl:ENSMUSP00000084062|uniprotkb:Q3U2D7 intact:EBI-647752|uniprotkb:Q61978|ensembl:ENSMUSP00000045993|ensembl:ENSMUSP00000114225 psi-mi:hes6_mouse(display_long)|uniprotkb:Hairy and enhancer of split 6(gene name synonym)|uniprotkb:Hes6(gene name)|psi-mi:Hes6(display_short) psi-mi:mycn_mouse(display_long)|uniprotkb:Mycn(gene name)|psi-mi:Mycn(display_short)|uniprotkb:Nmyc(gene name synonym)|uniprotkb:Nmyc1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679263|imex:IM-28774-2557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000067071(gene)|ensembl:ENSMUST00000086851(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_062352.1|entrezgene/locuslink:55927(identity) refseq:NP_032735.3|dip:DIP-49592N|ensembl:ENSMUSG00000037169(gene)|ensembl:ENSMUST00000043396(transcript)|ensembl:ENSMUST00000130990(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019900"(kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|entrezgene/locuslink:18109(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8Rl2iUFTAf9Tc8GEFc1uduxDVXw10090 rogid:J+RjU57FyHczGnzHYpNaUKOiw6k10090 rigid:PAaddepkKFtWhHaau626DCCLmjc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TAP4 uniprotkb:O43679 intact:EBI-742259|uniprotkb:Q58A66|uniprotkb:Q8N974|uniprotkb:Q9UDD5|ensembl:ENSP00000312856|ensembl:ENSP00000346689|ensembl:ENSP00000412479|ensembl:ENSP00000413703|ensembl:ENSP00000439275|ensembl:ENSP00000440099|ensembl:ENSP00000444393|ensembl:ENSP00000445751|ensembl:ENSP00000446115|uniprotkb:B4DH35|uniprotkb:Q58A67|uniprotkb:B4DG90 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:lmo3_human(display_long)|uniprotkb:LMO3(gene name)|psi-mi:LMO3(display_short)|uniprotkb:RBTN3(gene name synonym)|uniprotkb:RHOM3(gene name synonym)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Rhombotin-3(gene name synonym)|uniprotkb:RBTNL2(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679224|imex:IM-28774-1241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001395.1|refseq:NP_001230538.1|refseq:NP_001230539.1|refseq:NP_061110.2|refseq:NP_001230540.1|ensembl:ENSG00000048540(gene)|ensembl:ENST00000320122(transcript)|ensembl:ENST00000354662(transcript)|ensembl:ENST00000441439(transcript)|ensembl:ENST00000447609(transcript)|ensembl:ENST00000534946(transcript)|ensembl:ENST00000535535(transcript)|ensembl:ENST00000537304(transcript)|ensembl:ENST00000540848(transcript)|ensembl:ENST00000541846(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:XP_011519064.1|refseq:XP_011519065.1|refseq:NP_001230542.1|refseq:NP_001230541.1|refseq:XP_006719173.1|refseq:XP_006719174.1|dip:DIP-50129N|entrezgene/locuslink:55885(identity) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|entrezgene/locuslink:9079(identity) - crc64:05284546BA5EC226 crc64:E86387BA027F383A figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:AlQejbNvt3mQ+ItvtVttm9MLrn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43593 uniprotkb:P14373 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679200|imex:IM-28774-1237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2|entrezgene/locuslink:55806(identity) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rigid:l377CBxU3u4980e3/x2ZaQuGqDI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VE42 uniprotkb:Q07279 intact:EBI-26679519|ensembl:ENSMUSP00000034406|ensembl:ENSMUSP00000149874|ensembl:ENSMUSP00000151079|uniprotkb:Q9Z2S1 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:anr49_mouse(display_long)|uniprotkb:Fetal globin-increasing factor(gene name synonym)|uniprotkb:Fetal globin-inducing factor(gene name synonym)|uniprotkb:Ankrd49(gene name)|psi-mi:Ankrd49(display_short)|uniprotkb:Fgif(gene name synonym)|uniprotkb:Gbif(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679551|imex:IM-28774-2565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031931(gene)|ensembl:ENSMUST00000034406(transcript)|ensembl:ENSMUST00000216037(transcript)|ensembl:ENSMUST00000216372(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001335189.1|refseq:NP_062657.2|refseq:XP_006510566.1|entrezgene/locuslink:56503(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NBGjCs77wOEzFXWWR/XmdAZ4KK810090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:+rR4a1e1JQiiuL7DVk6rAWg28os false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JHE6 uniprotkb:Q9JLC6 intact:EBI-26679232|ensembl:ENSMUSP00000084062|uniprotkb:Q3U2D7 intact:EBI-26673698|ensembl:ENSMUSP00000023024|uniprotkb:Q3U426|uniprotkb:Q3UGF4|uniprotkb:Q3UM49|uniprotkb:Q3URC8|uniprotkb:Q6QHT6|uniprotkb:Q8C6I0|uniprotkb:Q8VD02 psi-mi:hes6_mouse(display_long)|uniprotkb:Hairy and enhancer of split 6(gene name synonym)|uniprotkb:Hes6(gene name)|psi-mi:Hes6(display_short) psi-mi:tef_mouse(display_long)|uniprotkb:Tef(gene name)|psi-mi:Tef(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679271|imex:IM-28774-1243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000067071(gene)|ensembl:ENSMUST00000086851(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_062352.1|entrezgene/locuslink:55927(identity) ensembl:ENSMUSG00000022389(gene)|ensembl:ENSMUST00000023024(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029832|interpro:IPR040223|refseq:NP_059072.1|refseq:NP_705617.2|entrezgene/locuslink:21685(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8Rl2iUFTAf9Tc8GEFc1uduxDVXw10090 rogid:jwxlAGyo8n8VADk3MLvjSIP19lE10090 rigid:ws6xCE8i4CcU7g4PEE8pGFvZXao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKB3 uniprotkb:P31245 intact:EBI-6393175|ensembl:ENSMUSP00000032309|uniprotkb:Q80WG4|uniprotkb:Q9EQF7|uniprotkb:Q9EQF8 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:ybox3_mouse(display_long)|uniprotkb:Ybx3(gene name)|psi-mi:Ybx3(display_short)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:Csda(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Msy4(gene name synonym)|uniprotkb:Y-box protein 3(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679511|imex:IM-28774-2139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000030189(gene)|ensembl:ENSMUST00000032309(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005921"(gap junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:Q9JKB3|refseq:NP_035863.1|refseq:NP_620817.2|dip:DIP-42746N|entrezgene/locuslink:56449(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:I3eJeqmpBnfBbKCvGcUGsqNagC810090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:PJrVPMkoE2nAWuUmNJ8y1jMO9Ws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QXN3 uniprotkb:P15806 intact:EBI-26679439|ensembl:ENSMUSP00000112385|ensembl:ENSMUSP00000113949|uniprotkb:E9QK64|uniprotkb:Q8CAD5 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:trip4_mouse(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:Trip4(gene name)|psi-mi:Trip4(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679503|imex:IM-28774-2997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032386(gene)|ensembl:ENSMUST00000117083(transcript)|ensembl:ENSMUST00000119245(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|refseq:NP_001164378.1|refseq:NP_062771.2|refseq:XP_006511359.1|refseq:XP_006511361.1|refseq:XP_006511362.1|refseq:XP_017168981.1|refseq:XP_017168982.1|entrezgene/locuslink:56404(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7EojDYCa39R5sz+4Daq2Fjl36hY10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:re1i/LykjckHSkSVsTFRTTkvxBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QXN3 uniprotkb:Q07279 intact:EBI-26679439|ensembl:ENSMUSP00000112385|ensembl:ENSMUSP00000113949|uniprotkb:E9QK64|uniprotkb:Q8CAD5 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:trip4_mouse(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:Trip4(gene name)|psi-mi:Trip4(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679495|imex:IM-28774-1669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032386(gene)|ensembl:ENSMUST00000117083(transcript)|ensembl:ENSMUST00000119245(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|refseq:NP_001164378.1|refseq:NP_062771.2|refseq:XP_006511359.1|refseq:XP_006511361.1|refseq:XP_006511362.1|refseq:XP_017168981.1|refseq:XP_017168982.1|entrezgene/locuslink:56404(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7EojDYCa39R5sz+4Daq2Fjl36hY10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:0va2WhDEmYD3MebeMP/Q5UwVS40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QXN3 uniprotkb:Q61545 intact:EBI-26679439|ensembl:ENSMUSP00000112385|ensembl:ENSMUSP00000113949|uniprotkb:E9QK64|uniprotkb:Q8CAD5 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:trip4_mouse(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:Trip4(gene name)|psi-mi:Trip4(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679487|imex:IM-28774-2995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032386(gene)|ensembl:ENSMUST00000117083(transcript)|ensembl:ENSMUST00000119245(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|refseq:NP_001164378.1|refseq:NP_062771.2|refseq:XP_006511359.1|refseq:XP_006511361.1|refseq:XP_006511362.1|refseq:XP_017168981.1|refseq:XP_017168982.1|entrezgene/locuslink:56404(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7EojDYCa39R5sz+4Daq2Fjl36hY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:W68bqtZgRQ3xLgpMP+ycdaqQ8Ss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92786 uniprotkb:Q15306 intact:EBI-3912635|uniprotkb:Q8TB91|uniprotkb:A6NK29|uniprotkb:Q5SW76|uniprotkb:A8K2B1|ensembl:ENSP00000261454|ensembl:ENSP00000355925|ensembl:ENSP00000400694|ensembl:ENSP00000420283 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 psi-mi:prox1_human(display_long)|uniprotkb:PROX1(gene name)|psi-mi:PROX1(display_short)|uniprotkb:Homeobox prospero-like protein PROX1(gene name synonym) psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679431|imex:IM-28774-1667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002754.2|refseq:NP_001257545.1|ensembl:ENSG00000117707(gene)|ensembl:ENST00000261454(transcript)|ensembl:ENST00000366958(transcript)|ensembl:ENST00000435016(transcript)|ensembl:ENST00000498508(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002194"(hepatocyte cell migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030324"(lung development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0031016"(pancreas development)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043049"(otic placode formation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046619"(lens placode formation involved in camera-type eye formation)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0055005"(ventricular cardiac myofibril assembly)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060214"(endocardium formation)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060836"(lymphatic endothelial cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|go:"GO:0061114"(branching involved in pancreas morphogenesis)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070858"(negative regulation of bile acid biosynthetic process)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090425"(acinar cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1901978"(positive regulation of cell cycle checkpoint)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000979"(positive regulation of forebrain neuron differentiation)|interpro:IPR007738(Homeobox prospero-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR023082|interpro:IPR037131|interpro:IPR039350|mint:Q92786|rcsb pdb:2LMD|refseq:XP_016857322.1|entrezgene/locuslink:5629(identity) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:80GpGEDggRkdm+tl6WhIz3FDfos9606 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rigid:+u7uk/YjFrvaDYq1IBin7Pr8qJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:Q9D3J5 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-26679409|ensembl:ENSMUSP00000025686|uniprotkb:Q9CZ89|uniprotkb:Q9D3I2 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:anr22_mouse(display_long)|uniprotkb:Ankrd22(gene name)|psi-mi:Ankrd22(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679423|imex:IM-28774-3397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) ensembl:ENSMUSG00000024774(gene)|ensembl:ENSMUST00000025686(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042802|refseq:NP_077166.4|entrezgene/locuslink:52024(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:YVrfJTKw4+yPbNOBJTHLJFEeQ8w10090 rigid:L1ZFeskqbqyUlL1FYkk0d3gQymw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:Q9QZ09 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-26679376|ensembl:ENSMUSP00000066607|ensembl:ENSMUSP00000113973|ensembl:ENSMUSP00000114722|uniprotkb:Q9CS51|uniprotkb:Q9CSB9|uniprotkb:Q9QZ14 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:phtf1_mouse(display_long)|uniprotkb:Phtf1(gene name)|psi-mi:Phtf1(display_short)|uniprotkb:Phtf(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679401|imex:IM-28774-2137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) ensembl:ENSMUSG00000058388(gene)|ensembl:ENSMUST00000063717(transcript)|ensembl:ENSMUST00000117150(transcript)|ensembl:ENSMUST00000145727(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0016021"(integral component of membrane)|interpro:IPR021980|interpro:IPR039775|refseq:NP_001156939.1|refseq:NP_001156940.1|refseq:NP_001156941.1|refseq:NP_038657.2|entrezgene/locuslink:18685(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:wLnEW8zlV74PlNap0RBkmuo4jG410090 rigid:3P6ZmOeWGtmgJTgodBeVPj2Svxc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:Q3UHF7 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-26679327|ensembl:ENSMUSP00000015645|ensembl:ENSMUSP00000140150|ensembl:ENSMUSP00000140290|uniprotkb:O55140|uniprotkb:Q3UVD4|uniprotkb:Q3UVH5 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:zep2_mouse(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2 homolog(gene name synonym)|uniprotkb:Myc intron-binding protein 1(gene name synonym)|uniprotkb:Hivep2(gene name)|psi-mi:Hivep2(display_short)|uniprotkb:Mibp1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679368|imex:IM-28774-1665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) ensembl:ENSMUST00000191138(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSMUSG00000015501(gene)|ensembl:ENSMUST00000015645(transcript)|ensembl:ENSMUST00000187083(transcript)|refseq:NP_034567.2|refseq:XP_006512619.1|refseq:XP_006512621.1|refseq:XP_006512622.1|refseq:XP_006512624.1|refseq:XP_011241431.1|refseq:XP_011241432.1|refseq:XP_011241433.1|refseq:XP_011241434.1|refseq:XP_011241435.1|refseq:XP_017169296.1|refseq:XP_017169297.1|refseq:XP_017169298.1|entrezgene/locuslink:15273(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:/iduDEqkuvx1jTmDWxFTu4xaVeA10090 rigid:rzSNEwrS/Ve7CTnvploD+VcfDKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:Q61188 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679319|imex:IM-28774-1247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750|entrezgene/locuslink:14056(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090 rigid:w/7g5qH+YRopmRnr1OU29/BwYQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:P79621 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679311|imex:IM-28774-2563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:hv0Seisj26J6LdmiSRPDfBe+BzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WUL8 uniprotkb:Q60668 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 intact:EBI-299932|ensembl:ENSMUSP00000132735|uniprotkb:Q91X94|uniprotkb:Q60667|uniprotkb:Q80ZJ0 psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:hnrpd_mouse(display_long)|uniprotkb:Hnrnpd(gene name)|psi-mi:Hnrnpd(display_short)|uniprotkb:Auf1(gene name synonym)|uniprotkb:Hnrpd(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679303|imex:IM-28774-2561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) ensembl:ENSMUSG00000000568(gene)|ensembl:ENSMUST00000172361(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q60668|reactome:R-MMU-450408|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0042752"(regulation of circadian rhythm)|refseq:NP_001070733.1|refseq:NP_001070734.1|refseq:NP_001070735.1|refseq:NP_031542.2|refseq:XP_006534798.1|dip:DIP-31411N|entrezgene/locuslink:11991(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rogid:lGvmHnn59pHQTtZq6H6ijlvXvt010090 rigid:NOGHIps0WhmohhRO4YQzoIkWR/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JL10 uniprotkb:D3Z4R4 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 intact:EBI-26673198|ensembl:ENSMUSP00000095588|ensembl:ENSMUSP00000101701 psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:d3z4r4_mouse(display_long)|uniprotkb:Nkx6-2(gene name)|psi-mi:Nkx6-2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679295|imex:IM-28774-1245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) ensembl:ENSMUSG00000041309(gene)|ensembl:ENSMUST00000097974(transcript)|ensembl:ENSMUST00000106095(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010455"(positive regulation of cell fate commitment)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031641"(regulation of myelination)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_899071.2|entrezgene/locuslink:14912(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rogid:8uwDwWnjt2gFmwB282nVs56MH/I10090 rigid:Co4edSNi5V36FllmcpOwyTlOiSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JHE6 uniprotkb:Q62440 intact:EBI-26679232|ensembl:ENSMUSP00000084062|uniprotkb:Q3U2D7 intact:EBI-604471|uniprotkb:Q5SQA8 psi-mi:hes6_mouse(display_long)|uniprotkb:Hairy and enhancer of split 6(gene name synonym)|uniprotkb:Hes6(gene name)|psi-mi:Hes6(display_short) psi-mi:tle1_mouse(display_long)|uniprotkb:Groucho-related protein 1(gene name synonym)|uniprotkb:Tle1(gene name)|psi-mi:Tle1(display_short)|uniprotkb:Grg1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679287|imex:IM-28774-2559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000067071(gene)|ensembl:ENSMUST00000086851(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_062352.1|entrezgene/locuslink:55927(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|refseq:NP_001272459.1|refseq:NP_001272460.1|refseq:NP_001272461.1|refseq:NP_035729.3|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|reactome:R-MMU-3769402|reactome:R-MMU-4641265|reactome:R-MMU-201722|interpro:IPR036322|entrezgene/locuslink:21885(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8Rl2iUFTAf9Tc8GEFc1uduxDVXw10090 rogid:r3QLjGnkeRB/hWa89Eey21sS2xk10090 rigid:ZzcUUHcAkotExjqRu71+axox1K4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JHE6 uniprotkb:Q62440 intact:EBI-26679232|ensembl:ENSMUSP00000084062|uniprotkb:Q3U2D7 intact:EBI-604471|uniprotkb:Q5SQA8 psi-mi:hes6_mouse(display_long)|uniprotkb:Hairy and enhancer of split 6(gene name synonym)|uniprotkb:Hes6(gene name)|psi-mi:Hes6(display_short) psi-mi:tle1_mouse(display_long)|uniprotkb:Groucho-related protein 1(gene name synonym)|uniprotkb:Tle1(gene name)|psi-mi:Tle1(display_short)|uniprotkb:Grg1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679279|imex:IM-28774-755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000067071(gene)|ensembl:ENSMUST00000086851(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_062352.1|entrezgene/locuslink:55927(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|refseq:NP_001272459.1|refseq:NP_001272460.1|refseq:NP_001272461.1|refseq:NP_035729.3|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|reactome:R-MMU-3769402|reactome:R-MMU-4641265|reactome:R-MMU-201722|interpro:IPR036322|entrezgene/locuslink:21885(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8Rl2iUFTAf9Tc8GEFc1uduxDVXw10090 rogid:r3QLjGnkeRB/hWa89Eey21sS2xk10090 rigid:ZzcUUHcAkotExjqRu71+axox1K4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VE42 uniprotkb:Q61545 intact:EBI-26679519|ensembl:ENSMUSP00000034406|ensembl:ENSMUSP00000149874|ensembl:ENSMUSP00000151079|uniprotkb:Q9Z2S1 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:anr49_mouse(display_long)|uniprotkb:Fetal globin-increasing factor(gene name synonym)|uniprotkb:Fetal globin-inducing factor(gene name synonym)|uniprotkb:Ankrd49(gene name)|psi-mi:Ankrd49(display_short)|uniprotkb:Fgif(gene name synonym)|uniprotkb:Gbif(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679543|imex:IM-28774-3399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031931(gene)|ensembl:ENSMUST00000034406(transcript)|ensembl:ENSMUST00000216037(transcript)|ensembl:ENSMUST00000216372(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001335189.1|refseq:NP_062657.2|refseq:XP_006510566.1|entrezgene/locuslink:56503(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NBGjCs77wOEzFXWWR/XmdAZ4KK810090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:Q07fCjopRTqyB8mJm0HZjQkzidQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULM2 uniprotkb:Q8N653 intact:EBI-1105370|ensembl:ENSP00000311521 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:zn490_human(display_long)|uniprotkb:ZNF490(gene name)|psi-mi:ZNF490(display_short)|uniprotkb:KIAA1198(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679886|imex:IM-28774-3001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188033(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|ensembl:ENST00000311437(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_065765.1|entrezgene/locuslink:57474(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:N096K1BEtmrLYDJFF0LAym6zZBg9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:4dhGQvm0wHMCji2Ow5IVGEOUTYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N680 uniprotkb:P42226 intact:EBI-2515601|ensembl:ENSP00000323183|uniprotkb:A8K7C7|uniprotkb:Q9P245|uniprotkb:Q5SZ81 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:zbtb2_human(display_long)|uniprotkb:ZBTB2(gene name)|psi-mi:ZBTB2(display_short)|uniprotkb:KIAA1483(gene name synonym)|uniprotkb:ZNF437(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679894|imex:IM-28774-2143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000181472(gene)|ensembl:ENST00000325144(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR011333(BTB/POZ fold)|refseq:XP_011534306.1|refseq:NP_065912.1|refseq:XP_005267133.1|dip:DIP-53681N|entrezgene/locuslink:57621(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:J8GO/U3lUReim2GO9Xq7D3dRZBQ9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:Oc78vxDAJq5x0mTY5Nr23xqqaZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULM2 uniprotkb:Q9UL17 intact:EBI-1105370|ensembl:ENSP00000311521 intact:EBI-3922312|ensembl:ENSP00000177694 psi-mi:zn490_human(display_long)|uniprotkb:ZNF490(gene name)|psi-mi:ZNF490(display_short)|uniprotkb:KIAA1198(gene name synonym) psi-mi:tbx21_human(display_long)|uniprotkb:TBX21(gene name)|psi-mi:TBX21(display_short)|uniprotkb:TBET(gene name synonym)|uniprotkb:TBLYM(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679878|imex:IM-28774-761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188033(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|ensembl:ENST00000311437(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_065765.1|entrezgene/locuslink:57474(identity) dip:DIP-61303N|refseq:NP_037483.1|ensembl:ENSG00000073861(gene)|ensembl:ENST00000177694(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009615"(response to virus)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|entrezgene/locuslink:30009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:N096K1BEtmrLYDJFF0LAym6zZBg9606 rogid:pBAiEOJJCYZznQ5p/T7l1lkBYfs9606 rigid:dsHGnr1yYOZYPzRGrDmx3POZvXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULM2 uniprotkb:P38159 intact:EBI-1105370|ensembl:ENSP00000311521 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:zn490_human(display_long)|uniprotkb:ZNF490(gene name)|psi-mi:ZNF490(display_short)|uniprotkb:KIAA1198(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679870|imex:IM-28774-3411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188033(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|ensembl:ENST00000311437(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_065765.1|entrezgene/locuslink:57474(identity) ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:N096K1BEtmrLYDJFF0LAym6zZBg9606 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 rigid:G8SzYBmytydioNl23OFJ6QfMRGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULM2 uniprotkb:Q9Y2Y4 intact:EBI-1105370|ensembl:ENSP00000311521 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 psi-mi:zn490_human(display_long)|uniprotkb:ZNF490(gene name)|psi-mi:ZNF490(display_short)|uniprotkb:KIAA1198(gene name synonym) psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679862|imex:IM-28774-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188033(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|ensembl:ENST00000311437(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_065765.1|entrezgene/locuslink:57474(identity) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1|entrezgene/locuslink:27033(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:N096K1BEtmrLYDJFF0LAym6zZBg9606 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rigid:LXJM9ZXepjmQLRnhZomB8UOB+vE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULM2 uniprotkb:Q15287 intact:EBI-1105370|ensembl:ENSP00000311521 intact:EBI-395959|uniprotkb:A8K1P0|uniprotkb:B4DDU8|uniprotkb:B4DZU7|uniprotkb:B7ZA17|uniprotkb:O75308|uniprotkb:Q32P25|uniprotkb:Q8WY42|uniprotkb:Q9NYG3|ensembl:ENSP00000301730|ensembl:ENSP00000315859|ensembl:ENSP00000380275|ensembl:ENSP00000457723|ensembl:ENSP00000457820 psi-mi:zn490_human(display_long)|uniprotkb:ZNF490(gene name)|psi-mi:ZNF490(display_short)|uniprotkb:KIAA1198(gene name synonym) psi-mi:rnps1_human(display_long)|uniprotkb:SR-related protein LDC2(gene name synonym)|uniprotkb:RNPS1(gene name)|psi-mi:RNPS1(display_short)|uniprotkb:LDC2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679854|imex:IM-28774-2583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188033(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|ensembl:ENST00000311437(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_065765.1|entrezgene/locuslink:57474(identity) refseq:NP_006702.1|refseq:NP_542161.1|refseq:NP_001273554.1|refseq:NP_001273555.1|refseq:NP_001273556.1|ensembl:ENSG00000205937(gene)|ensembl:ENST00000301730(transcript)|ensembl:ENST00000320225(transcript)|ensembl:ENST00000397086(transcript)|ensembl:ENST00000565678(transcript)|ensembl:ENST00000568631(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034201|interpro:IPR035979|mint:Q15287|rcsb pdb:4A8X|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:XP_005255105.1|refseq:XP_005255106.1|refseq:XP_016878363.1|dip:DIP-32943N|entrezgene/locuslink:10921(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:N096K1BEtmrLYDJFF0LAym6zZBg9606 rogid:nANu/nh/pD/F6dYE2Sa28OegPGs9606 rigid:bRkr/bxmtcqHmsul4TEAtA7LARc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92826 uniprotkb:Q9ULM2 intact:EBI-11317274|uniprotkb:Q96QM4|uniprotkb:Q99810|uniprotkb:B2R878|ensembl:ENSP00000290295 intact:EBI-1105370|ensembl:ENSP00000311521 psi-mi:hxb13_human(display_long)|uniprotkb:HOXB13(gene name)|psi-mi:HOXB13(display_short) psi-mi:zn490_human(display_long)|uniprotkb:ZNF490(gene name)|psi-mi:ZNF490(display_short)|uniprotkb:KIAA1198(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679846|imex:IM-28774-2999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006352.2|ensembl:ENSG00000159184(gene)|ensembl:ENST00000290295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2CRA|rcsb pdb:5EDN|rcsb pdb:5EEA|rcsb pdb:5EF6|rcsb pdb:5EG0|rcsb pdb:5EGO|rcsb pdb:5NO6|entrezgene/locuslink:10481(identity) ensembl:ENSG00000188033(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|ensembl:ENST00000311437(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_065765.1|entrezgene/locuslink:57474(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1SnzRAM4GtQSqYfsGf209weqvyw9606 rogid:N096K1BEtmrLYDJFF0LAym6zZBg9606 rigid:E0cqRR8fJochIhFzK5MjF245YpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54941 uniprotkb:O55144 intact:EBI-642789|uniprotkb:Q8BPD9|ensembl:ENSMUSP00000099422 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:smce1_mouse(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:Smarce1(gene name)|psi-mi:Smarce1(display_short)|uniprotkb:Baf57(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679838|imex:IM-28774-3409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065643.1|ensembl:ENSMUSG00000037935(gene)|ensembl:ENSMUST00000103133(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:O54941|reactome:R-MMU-3214858|reactome:R-MMU-8939243|go:"GO:0003677"(DNA binding)|dip:DIP-39985N|entrezgene/locuslink:57376(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W5MLVNJ0Jj6hoGwVy2E2HzKx/fY10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:4MH2omxhsaeftMYNMYRd1HumKm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54941 uniprotkb:P15806 intact:EBI-642789|uniprotkb:Q8BPD9|ensembl:ENSMUSP00000099422 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:smce1_mouse(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:Smarce1(gene name)|psi-mi:Smarce1(display_short)|uniprotkb:Baf57(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679830|imex:IM-28774-1675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065643.1|ensembl:ENSMUSG00000037935(gene)|ensembl:ENSMUST00000103133(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:O54941|reactome:R-MMU-3214858|reactome:R-MMU-8939243|go:"GO:0003677"(DNA binding)|dip:DIP-39985N|entrezgene/locuslink:57376(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W5MLVNJ0Jj6hoGwVy2E2HzKx/fY10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:sNYa94HlrB2MofK5tra5isiL3fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54941 uniprotkb:Q07279 intact:EBI-642789|uniprotkb:Q8BPD9|ensembl:ENSMUSP00000099422 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:smce1_mouse(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:Smarce1(gene name)|psi-mi:Smarce1(display_short)|uniprotkb:Baf57(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679822|imex:IM-28774-3407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065643.1|ensembl:ENSMUSG00000037935(gene)|ensembl:ENSMUST00000103133(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:O54941|reactome:R-MMU-3214858|reactome:R-MMU-8939243|go:"GO:0003677"(DNA binding)|dip:DIP-39985N|entrezgene/locuslink:57376(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W5MLVNJ0Jj6hoGwVy2E2HzKx/fY10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:dk32XGalKFPeQzB04zv95pYXq90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96AQ6 uniprotkb:P55201 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679814|imex:IM-28774-1251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N|entrezgene/locuslink:57326(identity) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N|entrezgene/locuslink:7862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rigid:sVJdZAqie2zKapygX0KSs/brkZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96AQ6 uniprotkb:Q8IYH5 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679806|imex:IM-28774-1673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N|entrezgene/locuslink:57326(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:CUnt+uw/kgWc3UfU6qgSkErbxv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CE64 uniprotkb:P25799 intact:EBI-26679773|ensembl:ENSMUSP00000001092|uniprotkb:Q3TQL7|uniprotkb:Q3V088|uniprotkb:Q80ZN3|uniprotkb:Q8C912|uniprotkb:Q9ESV2 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:zn276_mouse(display_long)|uniprotkb:Znf276(gene name)|psi-mi:Znf276(display_short)|uniprotkb:Zfp276(gene name synonym) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679798|imex:IM-28774-2581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000001065(gene)|ensembl:ENSMUST00000001092(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR012934(Zinc finger, AD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_065243.2|entrezgene/locuslink:57247(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fmH/tIANIQnwrm3yCHg6TvpK1WE10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:ZgdSnA8u8OEGd0kQJDakjcj2Dvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NSA3 uniprotkb:P35222 intact:EBI-747082|ensembl:ENSP00000366466|ensembl:ENSP00000366468|ensembl:ENSP00000366474|ensembl:ENSP00000383696|uniprotkb:Q5T4V2 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:cnbp1_human(display_long)|uniprotkb:Inhibitor of beta-catenin and Tcf-4(gene name synonym)|uniprotkb:CTNNBIP1(gene name)|psi-mi:CTNNBIP1(display_short)|uniprotkb:ICAT(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679765|imex:IM-28774-3405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012329.1|refseq:NP_064633.1|ensembl:ENSG00000178585(gene)|ensembl:ENST00000377256(transcript)|ensembl:ENST00000377258(transcript)|ensembl:ENST00000377263(transcript)|ensembl:ENST00000400904(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002528"(regulation of vascular permeability involved in acute inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|interpro:IPR009428(Beta-catenin-interacting ICAT)|interpro:IPR036911|interpro:IPR042999|rcsb pdb:1LUJ|rcsb pdb:1M1E|rcsb pdb:1T08|reactome:R-HSA-3769402|refseq:XP_016857342.1|refseq:XP_016857343.1|refseq:XP_016857344.1|entrezgene/locuslink:56998(identity) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|entrezgene/locuslink:1499(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+u/qGVFIboIBdcxthYr2OA1US3w9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:kBIRpUjF3mZpPf6yqcOUFeatCvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NSA3 uniprotkb:P35222 intact:EBI-747082|ensembl:ENSP00000366466|ensembl:ENSP00000366468|ensembl:ENSP00000366474|ensembl:ENSP00000383696|uniprotkb:Q5T4V2 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:cnbp1_human(display_long)|uniprotkb:Inhibitor of beta-catenin and Tcf-4(gene name synonym)|uniprotkb:CTNNBIP1(gene name)|psi-mi:CTNNBIP1(display_short)|uniprotkb:ICAT(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679757|imex:IM-28774-3403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001012329.1|refseq:NP_064633.1|ensembl:ENSG00000178585(gene)|ensembl:ENST00000377256(transcript)|ensembl:ENST00000377258(transcript)|ensembl:ENST00000377263(transcript)|ensembl:ENST00000400904(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002528"(regulation of vascular permeability involved in acute inflammatory response)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060633"(negative regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|interpro:IPR009428(Beta-catenin-interacting ICAT)|interpro:IPR036911|interpro:IPR042999|rcsb pdb:1LUJ|rcsb pdb:1M1E|rcsb pdb:1T08|reactome:R-HSA-3769402|refseq:XP_016857342.1|refseq:XP_016857343.1|refseq:XP_016857344.1|entrezgene/locuslink:56998(identity) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|entrezgene/locuslink:1499(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+u/qGVFIboIBdcxthYr2OA1US3w9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:kBIRpUjF3mZpPf6yqcOUFeatCvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI90 uniprotkb:P32443 intact:EBI-6841039|uniprotkb:Q7TPR0|uniprotkb:Q9D0L2|uniprotkb:Q9D6N2|uniprotkb:Q9D6Z8|uniprotkb:Q9JI89|ensembl:ENSMUSP00000072212|ensembl:ENSMUSP00000126205|ensembl:ENSMUSP00000157833 intact:EBI-26670247|ensembl:ENSMUSP00000043587|uniprotkb:Q544T6 psi-mi:rnf14_mouse(display_long)|uniprotkb:Rnf14(gene name)|psi-mi:Rnf14(display_short)|uniprotkb:Ara54(gene name synonym)|uniprotkb:Triad2(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Protein Triad2(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym) psi-mi:meox2_mouse(display_long)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Meox2(gene name)|psi-mi:Meox2(display_short)|uniprotkb:Gax(gene name synonym)|uniprotkb:Mox-2(gene name synonym)|uniprotkb:Mox2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679635|imex:IM-28774-3401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158093.1|refseq:NP_001158094.1|refseq:NP_064396.2|refseq:XP_017173444.1|refseq:XP_017173445.1|refseq:XP_017173446.1|ensembl:ENSMUSG00000060450(gene)|ensembl:ENSMUST00000072376(transcript)|ensembl:ENSMUST00000171461(transcript)|ensembl:ENSMUST00000236116(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|reactome:R-MMU-983168|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_006526184.1|refseq:XP_006526185.1|refseq:XP_006526186.1|refseq:XP_006526187.1|refseq:XP_006526188.1|refseq:XP_006526189.1|refseq:XP_006526190.1|entrezgene/locuslink:56736(identity) go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensembl:ENSMUSG00000036144(gene)|ensembl:ENSMUST00000041183(transcript)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_032610.1|entrezgene/locuslink:17286(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Zwq8Ma519wCUdK60xVxmfxGGZvo10090 rogid:ubOalBHxttPOs8Fjii/bAUvcgSw10090 rigid:7J8gsWusRIIa/pvR+342gC8IbK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JL60 uniprotkb:Q9R164 intact:EBI-26679699|ensembl:ENSMUSP00000030733|ensembl:ENSMUSP00000101584|ensembl:ENSMUSP00000101585|ensembl:ENSMUSP00000131331|uniprotkb:Q80Y88 intact:EBI-26679575|ensembl:ENSMUSP00000129484 psi-mi:gmeb1_mouse(display_long)|uniprotkb:Gmeb1(gene name)|psi-mi:Gmeb1(display_short) psi-mi:q9r164_mouse(display_long)|uniprotkb:Zfp111(gene name)|psi-mi:Zfp111(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679749|imex:IM-28774-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028901(gene)|ensembl:ENSMUST00000030733(transcript)|ensembl:ENSMUST00000105964(transcript)|ensembl:ENSMUST00000105965(transcript)|ensembl:ENSMUST00000168553(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051008"(Hsp27 protein binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|refseq:NP_001116464.1|refseq:NP_064669.2|refseq:XP_006539141.1|refseq:XP_006539142.1|refseq:XP_006539143.1|refseq:XP_017175821.1|entrezgene/locuslink:56809(identity) ensembl:ENSMUSG00000087598(gene)|ensembl:ENSMUST00000056683(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001297599.1|refseq:NP_064324.2|entrezgene/locuslink:56707(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YIdkBFnwCIT+NYGvVCNFEwlr2e410090 rogid:qypxkZCg7xd/MVMbuWUVqTm9Afc10090 rigid:3YqOkIxBVD0uh3Pm32lvnO7AlRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JL60 uniprotkb:Q811S7 intact:EBI-26679699|ensembl:ENSMUSP00000030733|ensembl:ENSMUSP00000101584|ensembl:ENSMUSP00000101585|ensembl:ENSMUSP00000131331|uniprotkb:Q80Y88 intact:EBI-5710174|uniprotkb:A4QPG4|uniprotkb:Q3UPR3|uniprotkb:Q3US11|uniprotkb:Q60786|uniprotkb:Q8C514|ensembl:ENSMUSP00000081946|ensembl:ENSMUSP00000150023 psi-mi:gmeb1_mouse(display_long)|uniprotkb:Gmeb1(gene name)|psi-mi:Gmeb1(display_short) psi-mi:ubip1_mouse(display_long)|uniprotkb:Ubp1(gene name)|psi-mi:Ubp1(display_short)|uniprotkb:Cp2b(gene name synonym)|uniprotkb:Nf2d9(gene name synonym)|uniprotkb:Nuclear factor 2d9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679741|imex:IM-28774-1671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028901(gene)|ensembl:ENSMUST00000030733(transcript)|ensembl:ENSMUST00000105964(transcript)|ensembl:ENSMUST00000105965(transcript)|ensembl:ENSMUST00000168553(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051008"(Hsp27 protein binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|refseq:NP_001116464.1|refseq:NP_064669.2|refseq:XP_006539141.1|refseq:XP_006539142.1|refseq:XP_006539143.1|refseq:XP_017175821.1|entrezgene/locuslink:56809(identity) refseq:NP_001076788.1|refseq:NP_038727.1|refseq:XP_006512114.2|refseq:XP_006512117.2|ensembl:ENSMUSG00000009741(gene)|ensembl:ENSMUST00000084885(transcript)|ensembl:ENSMUST00000216558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q811S7|entrezgene/locuslink:22221(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YIdkBFnwCIT+NYGvVCNFEwlr2e410090 rogid:Nt11E5Wv/MovMgjsl1GUvjXxz8Y10090 rigid:YlrWsS8GLHHAkAmLr+0vIs5Bh5Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JL60 uniprotkb:P79621 intact:EBI-26679699|ensembl:ENSMUSP00000030733|ensembl:ENSMUSP00000101584|ensembl:ENSMUSP00000101585|ensembl:ENSMUSP00000131331|uniprotkb:Q80Y88 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:gmeb1_mouse(display_long)|uniprotkb:Gmeb1(gene name)|psi-mi:Gmeb1(display_short) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679733|imex:IM-28774-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028901(gene)|ensembl:ENSMUST00000030733(transcript)|ensembl:ENSMUST00000105964(transcript)|ensembl:ENSMUST00000105965(transcript)|ensembl:ENSMUST00000168553(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051008"(Hsp27 protein binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|refseq:NP_001116464.1|refseq:NP_064669.2|refseq:XP_006539141.1|refseq:XP_006539142.1|refseq:XP_006539143.1|refseq:XP_017175821.1|entrezgene/locuslink:56809(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YIdkBFnwCIT+NYGvVCNFEwlr2e410090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:tSJa1Sk7Iv+u4RtuQ/ZBrILpHSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R0X0 uniprotkb:G3X904 intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679691|imex:IM-28774-2579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436|entrezgene/locuslink:56771(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:3r/gSXHbhcnPCxnPfw/F8uKjqmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R0X0 uniprotkb:Q61545 intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679683|imex:IM-28774-1249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436|entrezgene/locuslink:56771(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:FdWBoz6PJMVLiSYs49u/Ymu46Fw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZE3 uniprotkb:Q04725 intact:EBI-1044954|uniprotkb:Q9NY88|uniprotkb:Q5T6V2|ensembl:ENSP00000263610|ensembl:ENSP00000444704 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 psi-mi:barh1_human(display_long)|uniprotkb:BARHL1(gene name)|psi-mi:BARHL1(display_short)|uniprotkb:FKSG31(orf name) psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679675|imex:IM-28774-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064448.1|go:"GO:0001764"(neuron migration)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030901"(midbrain development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|ensembl:ENSG00000125492(gene)|ensembl:ENST00000263610(transcript)|ensembl:ENST00000542090(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:56751(identity) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7Ea8/LdF9W/IljE12nTfBUWPBGk9606 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rigid:ehHaKzMF7XPL8Ob0AOJWGG9UVQw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZE3 uniprotkb:Q04724 intact:EBI-1044954|uniprotkb:Q9NY88|uniprotkb:Q5T6V2|ensembl:ENSP00000263610|ensembl:ENSP00000444704 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:barh1_human(display_long)|uniprotkb:BARHL1(gene name)|psi-mi:BARHL1(display_short)|uniprotkb:FKSG31(orf name) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679667|imex:IM-28774-2577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064448.1|go:"GO:0001764"(neuron migration)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030901"(midbrain development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|ensembl:ENSG00000125492(gene)|ensembl:ENST00000263610(transcript)|ensembl:ENST00000542090(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:56751(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7Ea8/LdF9W/IljE12nTfBUWPBGk9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:bSfCNTF0e9niQjE8ljaKuR9uw5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI90 uniprotkb:P15806 intact:EBI-6841039|uniprotkb:Q7TPR0|uniprotkb:Q9D0L2|uniprotkb:Q9D6N2|uniprotkb:Q9D6Z8|uniprotkb:Q9JI89|ensembl:ENSMUSP00000072212|ensembl:ENSMUSP00000126205|ensembl:ENSMUSP00000157833 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:rnf14_mouse(display_long)|uniprotkb:Rnf14(gene name)|psi-mi:Rnf14(display_short)|uniprotkb:Ara54(gene name synonym)|uniprotkb:Triad2(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Protein Triad2(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679659|imex:IM-28774-2575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158093.1|refseq:NP_001158094.1|refseq:NP_064396.2|refseq:XP_017173444.1|refseq:XP_017173445.1|refseq:XP_017173446.1|ensembl:ENSMUSG00000060450(gene)|ensembl:ENSMUST00000072376(transcript)|ensembl:ENSMUST00000171461(transcript)|ensembl:ENSMUST00000236116(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|reactome:R-MMU-983168|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_006526184.1|refseq:XP_006526185.1|refseq:XP_006526186.1|refseq:XP_006526187.1|refseq:XP_006526188.1|refseq:XP_006526189.1|refseq:XP_006526190.1|entrezgene/locuslink:56736(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Zwq8Ma519wCUdK60xVxmfxGGZvo10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:NyX9Rc9FAvMV8BHECDW35w+E0lc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI90 uniprotkb:Q07279 intact:EBI-6841039|uniprotkb:Q7TPR0|uniprotkb:Q9D0L2|uniprotkb:Q9D6N2|uniprotkb:Q9D6Z8|uniprotkb:Q9JI89|ensembl:ENSMUSP00000072212|ensembl:ENSMUSP00000126205|ensembl:ENSMUSP00000157833 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:rnf14_mouse(display_long)|uniprotkb:Rnf14(gene name)|psi-mi:Rnf14(display_short)|uniprotkb:Ara54(gene name synonym)|uniprotkb:Triad2(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Protein Triad2(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679651|imex:IM-28774-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158093.1|refseq:NP_001158094.1|refseq:NP_064396.2|refseq:XP_017173444.1|refseq:XP_017173445.1|refseq:XP_017173446.1|ensembl:ENSMUSG00000060450(gene)|ensembl:ENSMUST00000072376(transcript)|ensembl:ENSMUST00000171461(transcript)|ensembl:ENSMUST00000236116(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|reactome:R-MMU-983168|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_006526184.1|refseq:XP_006526185.1|refseq:XP_006526186.1|refseq:XP_006526187.1|refseq:XP_006526188.1|refseq:XP_006526189.1|refseq:XP_006526190.1|entrezgene/locuslink:56736(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Zwq8Ma519wCUdK60xVxmfxGGZvo10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:m+eYN9ks+N+qy7TefNMmnU1nq6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI90 uniprotkb:Q07243 intact:EBI-6841039|uniprotkb:Q7TPR0|uniprotkb:Q9D0L2|uniprotkb:Q9D6N2|uniprotkb:Q9D6Z8|uniprotkb:Q9JI89|ensembl:ENSMUSP00000072212|ensembl:ENSMUSP00000126205|ensembl:ENSMUSP00000157833 intact:EBI-26670765|ensembl:ENSMUSP00000030723|ensembl:ENSMUSP00000101799|uniprotkb:Q9JJW8 psi-mi:rnf14_mouse(display_long)|uniprotkb:Rnf14(gene name)|psi-mi:Rnf14(display_short)|uniprotkb:Ara54(gene name synonym)|uniprotkb:Triad2(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Protein Triad2(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym) psi-mi:mtf1_mouse(display_long)|uniprotkb:MRE-binding transcription factor(gene name synonym)|uniprotkb:Transcription factor MTF-1(gene name synonym)|uniprotkb:Mtf1(gene name)|psi-mi:Mtf1(display_short)|uniprotkb:Mtf-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679643|imex:IM-28774-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158093.1|refseq:NP_001158094.1|refseq:NP_064396.2|refseq:XP_017173444.1|refseq:XP_017173445.1|refseq:XP_017173446.1|ensembl:ENSMUSG00000060450(gene)|ensembl:ENSMUST00000072376(transcript)|ensembl:ENSMUST00000171461(transcript)|ensembl:ENSMUST00000236116(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|reactome:R-MMU-983168|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_006526184.1|refseq:XP_006526185.1|refseq:XP_006526186.1|refseq:XP_006526187.1|refseq:XP_006526188.1|refseq:XP_006526189.1|refseq:XP_006526190.1|entrezgene/locuslink:56736(identity) ensembl:ENSMUSG00000028890(gene)|ensembl:ENSMUST00000030723(transcript)|ensembl:ENSMUST00000106193(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:1990079"(cartilage homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029796|interpro:IPR036236|refseq:NP_032662.3|entrezgene/locuslink:17764(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Zwq8Ma519wCUdK60xVxmfxGGZvo10090 rogid:3a3aJs0bsRGzr9qHPcpSo5BxmBQ10090 rigid:6uZa0mAXRy53rzbTzQ536pXrYEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JI90 uniprotkb:Q9WTL8 intact:EBI-6841039|uniprotkb:Q7TPR0|uniprotkb:Q9D0L2|uniprotkb:Q9D6N2|uniprotkb:Q9D6Z8|uniprotkb:Q9JI89|ensembl:ENSMUSP00000072212|ensembl:ENSMUSP00000126205|ensembl:ENSMUSP00000157833 intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9 psi-mi:rnf14_mouse(display_long)|uniprotkb:Rnf14(gene name)|psi-mi:Rnf14(display_short)|uniprotkb:Ara54(gene name synonym)|uniprotkb:Triad2(gene name synonym)|uniprotkb:Androgen receptor-associated protein 54(gene name synonym)|uniprotkb:Protein Triad2(gene name synonym)|uniprotkb:RING finger protein 14(gene name synonym) psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679627|imex:IM-28774-759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158093.1|refseq:NP_001158094.1|refseq:NP_064396.2|refseq:XP_017173444.1|refseq:XP_017173445.1|refseq:XP_017173446.1|ensembl:ENSMUSG00000060450(gene)|ensembl:ENSMUST00000072376(transcript)|ensembl:ENSMUST00000171461(transcript)|ensembl:ENSMUST00000236116(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017907|interpro:IPR031127|interpro:IPR031128|interpro:IPR044066|reactome:R-MMU-983168|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_006526184.1|refseq:XP_006526185.1|refseq:XP_006526186.1|refseq:XP_006526187.1|refseq:XP_006526188.1|refseq:XP_006526189.1|refseq:XP_006526190.1|entrezgene/locuslink:56736(identity) refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8|entrezgene/locuslink:11865(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Zwq8Ma519wCUdK60xVxmfxGGZvo10090 rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090 rigid:SuFcEbqyXdMXoRE4uAssB7mIw2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R164 uniprotkb:Q9Z0Y9 intact:EBI-26679575|ensembl:ENSMUSP00000129484 intact:EBI-5276764|uniprotkb:Q9QUH7|ensembl:ENSMUSP00000002177|ensembl:ENSMUSP00000106986|ensembl:ENSMUSP00000106988 psi-mi:q9r164_mouse(display_long)|uniprotkb:Zfp111(gene name)|psi-mi:Zfp111(display_short) psi-mi:nr1h3_mouse(display_long)|uniprotkb:Nr1h3(gene name)|psi-mi:Nr1h3(display_short)|uniprotkb:Lxra(gene name synonym)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679619|imex:IM-28774-757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000087598(gene)|ensembl:ENSMUST00000056683(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001297599.1|refseq:NP_064324.2|entrezgene/locuslink:56707(identity) refseq:NP_001171201.1|refseq:NP_038867.2|refseq:XP_006499229.1|refseq:XP_006499230.1|refseq:XP_006499231.1|dip:DIP-62095N|rcsb pdb:3FAL|rcsb pdb:3FC6|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-8866427|reactome:R-MMU-9029569|reactome:R-MMU-9623433|ensembl:ENSMUSG00000002108(gene)|ensembl:ENSMUST00000002177(transcript)|ensembl:ENSMUST00000111354(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|ensembl:ENSMUST00000111356(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|rcsb pdb:2ACL|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:22259(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qypxkZCg7xd/MVMbuWUVqTm9Afc10090 rogid:plRi02INEW/CTelVP1it9J2FWAE10090 rigid:CwVkzgdzLNLP1CbYMvlIPXc9SQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R164 uniprotkb:Q07279 intact:EBI-26679575|ensembl:ENSMUSP00000129484 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:q9r164_mouse(display_long)|uniprotkb:Zfp111(gene name)|psi-mi:Zfp111(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679611|imex:IM-28774-2573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000087598(gene)|ensembl:ENSMUST00000056683(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001297599.1|refseq:NP_064324.2|entrezgene/locuslink:56707(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qypxkZCg7xd/MVMbuWUVqTm9Afc10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:L10rCZ3NMWFyb80iAF9W6dmD4YY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R164 uniprotkb:Q61545 intact:EBI-26679575|ensembl:ENSMUSP00000129484 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:q9r164_mouse(display_long)|uniprotkb:Zfp111(gene name)|psi-mi:Zfp111(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679603|imex:IM-28774-2141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000087598(gene)|ensembl:ENSMUST00000056683(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001297599.1|refseq:NP_064324.2|entrezgene/locuslink:56707(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qypxkZCg7xd/MVMbuWUVqTm9Afc10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:guBBnq3AfsAahmdZc9TmO348adk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R164 uniprotkb:P43136 intact:EBI-26679575|ensembl:ENSMUSP00000129484 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 psi-mi:q9r164_mouse(display_long)|uniprotkb:Zfp111(gene name)|psi-mi:Zfp111(display_short) psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679595|imex:IM-28774-2571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000087598(gene)|ensembl:ENSMUST00000056683(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|refseq:NP_001297599.1|refseq:NP_064324.2|entrezgene/locuslink:56707(identity) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:13864(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qypxkZCg7xd/MVMbuWUVqTm9Afc10090 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rigid:bG3D+hVMnseSTwneImAHppoUA38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WVP6 uniprotkb:P15806 intact:EBI-7842113|uniprotkb:Q9R1R3|intact:MINT-6167909 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:papob_mouse(display_long)|uniprotkb:Papolb(gene name)|psi-mi:Papolb(display_short)|uniprotkb:Papt(gene name synonym)|uniprotkb:Tpap(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase beta(gene name synonym)|uniprotkb:"Testis-specific poly(A) polymerase"(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679567|imex:IM-28774-2569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0046872"(metal ion binding)|mint:Q9WVP6|interpro:IPR043519|refseq:NP_064327.1|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR002934(Nucleotidyltransferase)|entrezgene/locuslink:56522(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UEeSyKz/SSxA85L6ctA0NUuGhHw10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:g5YCM1O5d6fp6kt88NxG9JkY/ss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60122 uniprotkb:Q9WTM5 intact:EBI-1634999|uniprotkb:O35753|ensembl:ENSMUSP00000032165 intact:EBI-2549911|ensembl:ENSMUSP00000103400|ensembl:ENSMUSP00000147502 psi-mi:ruvb1_mouse(display_long)|uniprotkb:Ruvbl1(gene name)|psi-mi:Ruvbl1(display_short)|uniprotkb:Tip49(gene name synonym)|uniprotkb:Tip49a(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:DNA helicase p50(gene name synonym) psi-mi:ruvb2_mouse(display_long)|uniprotkb:Ruvbl2(gene name)|psi-mi:Ruvbl2(display_short)|uniprotkb:p47 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679559|imex:IM-28774-2567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062659.1|ensembl:ENSMUSG00000030079(gene)|ensembl:ENSMUST00000032165(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:P60122|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5696394|reactome:R-MMU-606279|entrezgene/locuslink:56505(identity) ensembl:ENSMUSG00000003868(gene)|ensembl:ENSMUST00000107771(transcript)|ensembl:ENSMUST00000211214(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051117"(ATPase binding)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9WTM5|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_035434.1|refseq:XP_006540785.1|refseq:XP_006540786.1|entrezgene/locuslink:20174(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fZiQ7AurvKII0LYc+haBswAXfZ410090 rogid:tHnjngaz5qWy9sPXagFLp3TRDtA10090 rigid:Rp1EsaPaZO8yKHWVZNQ5jOP5xbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:O35137 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679934|imex:IM-28774-1677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:32cpOkvHx+mvLOokbuajluNq/Zk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48380 uniprotkb:Q01844 intact:EBI-742557|uniprotkb:Q5JTL7|uniprotkb:Q5JTL8|uniprotkb:Q6NW13|uniprotkb:Q8WTU4|uniprotkb:Q95HL5|uniprotkb:Q95HL6|uniprotkb:A8K0H5|uniprotkb:D3DRH8|uniprotkb:D3DRH9|ensembl:ENSP00000371434|ensembl:ENSP00000482598 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:rfx3_human(display_long)|uniprotkb:Regulatory factor X 3(gene name synonym)|uniprotkb:RFX3(gene name)|psi-mi:RFX3(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680046|imex:IM-28774-3419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002910.1|refseq:NP_602304.1|refseq:NP_001269045.1|refseq:NP_001269046.1|ensembl:ENSG00000080298(gene)|ensembl:ENST00000382004(transcript)|ensembl:ENST00000617270(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|entrezgene/locuslink:5991(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZaJnW0P0U9zhzPKADzUpbtwJptI9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:7mN98jWUG7gLcxaCCRT1ltRSges false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HCD5 uniprotkb:Q9HCD5 intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231 intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231 psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679910|imex:IM-28774-3413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066018.1|ensembl:ENSG00000124160(gene)|ensembl:ENST00000290231(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1|entrezgene/locuslink:57727(identity) refseq:NP_066018.1|ensembl:ENSG00000124160(gene)|ensembl:ENST00000290231(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1|entrezgene/locuslink:57727(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606 rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606 rigid:cLVggkNU/0NooYIt3OgzSUjvxDA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P1Z2 uniprotkb:P61457 intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679902|imex:IM-28774-3003 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:mG5RKaRhB/7WfItcFdbdCBWVVPE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48380 uniprotkb:P16220 intact:EBI-742557|uniprotkb:Q5JTL7|uniprotkb:Q5JTL8|uniprotkb:Q6NW13|uniprotkb:Q8WTU4|uniprotkb:Q95HL5|uniprotkb:Q95HL6|uniprotkb:A8K0H5|uniprotkb:D3DRH8|uniprotkb:D3DRH9|ensembl:ENSP00000371434|ensembl:ENSP00000482598 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:rfx3_human(display_long)|uniprotkb:Regulatory factor X 3(gene name synonym)|uniprotkb:RFX3(gene name)|psi-mi:RFX3(display_short) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680038|imex:IM-28774-2147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002910.1|refseq:NP_602304.1|refseq:NP_001269045.1|refseq:NP_001269046.1|ensembl:ENSG00000080298(gene)|ensembl:ENST00000382004(transcript)|ensembl:ENST00000617270(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|entrezgene/locuslink:5991(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZaJnW0P0U9zhzPKADzUpbtwJptI9606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:4q7r06atOOs/+WUpmawu17vNXkA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14373 uniprotkb:P35269 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680030|imex:IM-28774-765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N|entrezgene/locuslink:2962(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rigid:rTonB1qyIIyriyh3yCvk3v0wUy0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08999 uniprotkb:P61457 intact:EBI-971439|ensembl:ENSP00000262133|uniprotkb:Q15073|uniprotkb:Q16084|uniprotkb:Q92812|uniprotkb:B7Z913|uniprotkb:Q8NE70 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:rbl2_human(display_long)|uniprotkb:RBL2(gene name)|psi-mi:RBL2(display_short)|uniprotkb:RB2(gene name synonym)|uniprotkb:Retinoblastoma-related protein 2(gene name synonym)|uniprotkb:130 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:pRb2(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680022|imex:IM-28774-3417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103479(gene)|ensembl:ENST00000262133(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028308|interpro:IPR028309|interpro:IPR036915|mint:Q08999|rcsb pdb:4XI9|rcsb pdb:5C1D|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-9617828|refseq:NP_005602.3|refseq:NP_001310537.1|dip:DIP-425N|entrezgene/locuslink:5934(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2/u/ejPv7UkPWeZYyfJpZXf9Roc9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:fCe3jnnCPCU9mSvo8U5s6fBPujc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10826 uniprotkb:P23771 intact:EBI-2568838|uniprotkb:P12891|uniprotkb:Q00989|uniprotkb:Q15298|uniprotkb:Q9UN48 intact:EBI-6664760|ensembl:ENSP00000341619|uniprotkb:Q5VWG7|uniprotkb:Q5VWG8|uniprotkb:Q96J16 psi-mi:rarb_human(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym) psi-mi:gata3_human(display_long)|uniprotkb:GATA3(gene name)|psi-mi:GATA3(display_short)|uniprotkb:GATA-binding factor 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680014|imex:IM-28774-1259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000956.2|refseq:NP_057236.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0007165"(signal transduction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1HRA|rcsb pdb:1XAP|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:5UAN|rcsb pdb:6SSQ|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-5617472|refseq:NP_001277195.1|refseq:NP_001277205.1|refseq:NP_001277145.1|refseq:NP_001277146.1|interpro:IPR035500|mint:P10826|entrezgene/locuslink:5915(identity) ensembl:ENSG00000107485(gene)|ensembl:ENST00000346208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001764"(neuron migration)|go:"GO:0001806"(type IV hypersensitivity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002520"(immune system development)|go:"GO:0002572"(pro-T cell differentiation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009615"(response to virus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0031929"(TOR signaling)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035799"(ureter maturation)|go:"GO:0035898"(parathyroid hormone secretion)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045061"(thymic T cell selection)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072676"(lymphocyte migration)|go:"GO:0090102"(cochlea development)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000607"(negative regulation of cell proliferation involved in mesonephros development)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:2000703"(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation)|go:"GO:2000734"(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029521|interpro:IPR039355|rcsb pdb:4HC7|rcsb pdb:4HC9|rcsb pdb:4HCA|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-983231|go:"GO:2000683"(regulation of cellular response to X-ray)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060374"(mast cell differentiation)|go:"GO:0060676"(ureteric bud formation)|go:"GO:0061085"(regulation of histone H3-K27 methylation)|go:"GO:0061290"(canonical Wnt signaling pathway involved in metanephric kidney development)|go:"GO:0070888"(E-box binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0071599"(otic vesicle development)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0048589"(developmental growth)|refseq:XP_005252499.1|refseq:XP_005252500.1|refseq:NP_001002295.1|refseq:NP_002042.1|dip:DIP-61302N|entrezgene/locuslink:2625(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GviMMhEdTqNBuvQ8p2XTKxllgdc9606 rogid:CHTPVKH4qSR/pDIf/vMr+kChpzc9606 rigid:E372Ay0PI59vNWSuYzqSuL2p6Uk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86VK4 uniprotkb:Q9H2G9 intact:EBI-720304|uniprotkb:O00153|uniprotkb:Q9BQ19|ensembl:ENSP00000451763|uniprotkb:B4DR78|uniprotkb:B4DDV5 intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4 psi-mi:zn410_human(display_long)|uniprotkb:Zinc finger protein APA-1(gene name synonym)|uniprotkb:Another partner for ARF 1(gene name synonym)|uniprotkb:ZNF410(gene name)|psi-mi:ZNF410(display_short)|uniprotkb:APA1(gene name synonym) psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680006|imex:IM-28774-2145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229856.1|ensembl:ENSG00000119725(gene)|ensembl:ENST00000555044(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:6WMI|refseq:NP_001229855.1|refseq:NP_067011.1|refseq:NP_001229853.1|entrezgene/locuslink:57862(identity) refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oe1n/awl/uodcjNUOgHoix5bp9Y9606 rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606 rigid:aXIc+Fk6/lWSydEMq6eq0tl6JKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HCC6 uniprotkb:P61457 intact:EBI-2680288|uniprotkb:Q5SVA5|ensembl:ENSP00000304595 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:hes4_human(display_long)|uniprotkb:BHLHB42(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:Hairy and enhancer of split 4(gene name synonym)|uniprotkb:bHLH factor Hes4(gene name synonym)|uniprotkb:HES4(gene name)|psi-mi:HES4(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679998|imex:IM-28774-1257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135939.1|refseq:NP_066993.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000188290(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|ensembl:ENST00000304952(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0000785"(chromatin)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|entrezgene/locuslink:57801(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OHv5KLK08PgjwZIwpFRchPSBdAA9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:8ulyfGr4B8LSyLna/SKKiPTq63A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WUU5 uniprotkb:O75177 intact:EBI-3916882|uniprotkb:D6W5Q5|uniprotkb:Q9H689|uniprotkb:Q8N5Y5|uniprotkb:Q99995|uniprotkb:B2RE37|ensembl:ENSP00000287957 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:gatd1_human(display_long)|uniprotkb:GATAD1(gene name)|psi-mi:GATAD1(display_short)|uniprotkb:ODAG(gene name synonym)|uniprotkb:Ocular development-associated gene protein(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679990|imex:IM-28774-1681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066990.3|ensembl:ENSG00000157259(gene)|ensembl:ENST00000287957(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039050|mint:Q8WUU5|entrezgene/locuslink:57798(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mwq5yOlZTelKYR0VGr822k9K0Nk9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:Rka98v2zjKSTmB4i3Hk/wQLrRRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:O55144 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679982|imex:IM-28774-1255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:SCFE5ZLEvZmQoGM30T3SmxSWoIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:Q62296 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-9253444|uniprotkb:A2BDD5|uniprotkb:P70282|uniprotkb:Q61174|uniprotkb:Q61175|uniprotkb:Q62298|ensembl:ENSMUSP00000006311 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:tead4_mouse(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679974|imex:IM-28774-763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) refseq:NP_001074448.2|refseq:NP_035697.3|dip:DIP-59847N|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001825"(blastocyst formation)|go:"GO:0001830"(trophectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007566"(embryo implantation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027255|interpro:IPR038096|interpro:IPR041086|rcsb pdb:3JUA|rcsb pdb:4LN0|rcsb pdb:5GN0|rcsb pdb:5XJD|rcsb pdb:5Z2Q|rcsb pdb:6L9F|rcsb pdb:6SBA|reactome:R-MMU-2032785|reactome:R-MMU-8951671|entrezgene/locuslink:21679(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:6qqoXqstu1BjLsbgcHHoX0bJMgE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:P47242 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-3865062|ensembl:ENSMUSP00000001538|ensembl:ENSMUSP00000117928 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:pax9_mouse(display_long)|uniprotkb:Pax9(gene name)|psi-mi:Pax9(display_short)|uniprotkb:Pax-9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679966|imex:IM-28774-3415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) refseq:NP_035171.1|refseq:XP_006515642.1|refseq:XP_006515643.1|refseq:XP_006515644.1|ensembl:ENSMUSG00000001497(gene)|ensembl:ENSMUST00000001538(transcript)|ensembl:ENSMUST00000153250(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042481"(regulation of odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|refseq:XP_017170480.1|entrezgene/locuslink:18511(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:9DTnU8hPiIIyHwJfWxR0pQBwqSA10090 rigid:mhTrAxv1/NaV9+GWG+wlx5RKDRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:Q02591 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-7457485|intact:MINT-4998459|ensembl:ENSMUSP00000021513 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:gsc_mouse(display_long)|uniprotkb:Gsc(gene name)|psi-mi:Gsc(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679958|imex:IM-28774-3005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) refseq:NP_034481.1|ensembl:ENSMUSG00000021095(gene)|ensembl:ENSMUST00000021513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014036"(neural crest cell fate specification)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q02591|entrezgene/locuslink:14836(identity) - - comment:mint|function:Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like activity when transplanted into Xenopus embryos figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:JP8dHDpRfNvyjVVZh5foSMbWxyg10090 rigid:gDEASEpBWlzxYegQ3cb4zj5mt2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:Q64317 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-26668417|ensembl:ENSMUSP00000042413 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:dlx1_mouse(display_long)|uniprotkb:Dlx1(gene name)|psi-mi:Dlx1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679950|imex:IM-28774-1679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) ensembl:ENSMUSG00000041911(gene)|ensembl:ENSMUST00000037119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021544"(subpallium development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021893"(cerebral cortex GABAergic interneuron fate commitment)|go:"GO:0030154"(cell differentiation)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:1902871"(positive regulation of amacrine cell differentiation)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034183.1|refseq:XP_006498734.1|refseq:XP_006498735.1|refseq:XP_006498736.1|refseq:XP_017170794.1|refseq:XP_017170796.1|refseq:XP_017170800.1|entrezgene/locuslink:13390(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:HP0JcwmCXCeMu02tYenBudBF7gg10090 rigid:tZ/EZKVYP2lPAZ7GKGYzb6gtUhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKD8 uniprotkb:O35137 intact:EBI-3863870|uniprotkb:Q9R0A6|uniprotkb:Q3U150|ensembl:ENSMUSP00000001484 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:tbx21_mouse(display_long)|uniprotkb:Tbx21(gene name)|psi-mi:Tbx21(display_short)|uniprotkb:Tbet(gene name synonym)|uniprotkb:Tblym(gene name synonym)|uniprotkb:T-cell-specific T-box transcription factor T-bet(gene name synonym)|uniprotkb:Transcription factor TBLYM(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679942|imex:IM-28774-1253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062380.2|ensembl:ENSMUSG00000001444(gene)|ensembl:ENSMUST00000001484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030217"(T cell differentiation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0072676"(lymphocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:5T1J|entrezgene/locuslink:57765(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:v/+4VGXyQSObqpx7YheLLJNVS3s10090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:32cpOkvHx+mvLOokbuajluNq/Zk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96KN3 uniprotkb:P40424 intact:EBI-2692890|uniprotkb:Q63HL6|uniprotkb:Q86XD1|uniprotkb:B7Z5I5|uniprotkb:F5GZ15|ensembl:ENSP00000298282 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 psi-mi:pknx2_human(display_long)|uniprotkb:PREP2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym)|uniprotkb:PKNOX2(gene name)|psi-mi:PKNOX2(display_short) psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680294|imex:IM-28774-2587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071345.2|refseq:XP_011541246.1|refseq:XP_011541247.1|ensembl:ENSP00000298282|refseq:XP_005271699.1|ensembl:ENSG00000165495(gene)|ensembl:ENST00000298282(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:XP_016873599.1|entrezgene/locuslink:63876(identity) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xeaCbYA1G3WgDVcHtnhzgoSe/FI9606 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rigid:0eGrkV3DlpfqZcAlLVCwK6e9Zx4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48443 uniprotkb:P10826 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 intact:EBI-2568838|uniprotkb:P12891|uniprotkb:Q00989|uniprotkb:Q15298|uniprotkb:Q9UN48 psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:rarb_human(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680286|imex:IM-28774-2163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) refseq:NP_000956.2|refseq:NP_057236.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0007165"(signal transduction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1HRA|rcsb pdb:1XAP|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:5UAN|rcsb pdb:6SSQ|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-5617472|refseq:NP_001277195.1|refseq:NP_001277205.1|refseq:NP_001277145.1|refseq:NP_001277146.1|interpro:IPR035500|mint:P10826|entrezgene/locuslink:5915(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rogid:GviMMhEdTqNBuvQ8p2XTKxllgdc9606 rigid:ehk1AqZYYBXGhgS21/3lkrXCvpw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48443 uniprotkb:P10276 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680278|imex:IM-28774-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|entrezgene/locuslink:5914(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rigid:L1AH6hY08mVK37c4H7pLUwTTFEg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48443 uniprotkb:P37231 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680270|imex:IM-28774-1689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:+Xug1rCGsMRdH2PPi+Kr9VmVKXk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48443 uniprotkb:P37231 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680262|imex:IM-28774-3009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:+Xug1rCGsMRdH2PPi+Kr9VmVKXk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48443 uniprotkb:P09016 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680254|imex:IM-28774-1687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:J4w1erDpuIGW/G3/kWpgrHFEkSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28702 uniprotkb:P10826 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 intact:EBI-2568838|uniprotkb:P12891|uniprotkb:Q00989|uniprotkb:Q15298|uniprotkb:Q9UN48 psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:rarb_human(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680246|imex:IM-28774-779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) refseq:NP_000956.2|refseq:NP_057236.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0021756"(striatum development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0007165"(signal transduction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|rcsb pdb:1HRA|rcsb pdb:1XAP|rcsb pdb:4DM6|rcsb pdb:4DM8|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:5UAN|rcsb pdb:6SSQ|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-5617472|refseq:NP_001277195.1|refseq:NP_001277205.1|refseq:NP_001277145.1|refseq:NP_001277146.1|interpro:IPR035500|mint:P10826|entrezgene/locuslink:5915(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rogid:GviMMhEdTqNBuvQ8p2XTKxllgdc9606 rigid:fPU5id4btadev1bwA56lOxxksz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28702 uniprotkb:P10276 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680238|imex:IM-28774-3007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|entrezgene/locuslink:5914(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rigid:HluQs5cAaosDIvLgC0qv5DrjuiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28702 uniprotkb:P37231 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680230|imex:IM-28774-777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:pZTE4AQtemXgnjnnnnR7+ln1Q9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28702 uniprotkb:P37231 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680222|imex:IM-28774-2161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:pZTE4AQtemXgnjnnnnR7+ln1Q9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28702 uniprotkb:P43354 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 intact:EBI-2681738|uniprotkb:Q6NXU0|uniprotkb:Q16311|uniprotkb:Q53RZ2|ensembl:ENSP00000344479|ensembl:ENSP00000386747 psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:nr4a2_human(display_long)|uniprotkb:NOT(gene name synonym)|uniprotkb:NURR1(gene name synonym)|uniprotkb:TINUR(gene name synonym)|uniprotkb:Immediate-early response protein NOT(gene name synonym)|uniprotkb:Orphan nuclear receptor NURR1(gene name synonym)|uniprotkb:Transcriptionally-inducible nuclear receptor(gene name synonym)|uniprotkb:NR4A2(gene name)|psi-mi:NR4A2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680214|imex:IM-28774-775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) refseq:XP_005246679.1|refseq:NP_006177.1|ensembl:ENSG00000153234(gene)|ensembl:ENST00000339562(transcript)|ensembl:ENST00000409572(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016607"(nuclear speck)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0021953"(central nervous system neuron differentiation)|go:"GO:0021986"(habenula development)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042551"(neuron maturation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051866"(general adaptation syndrome)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003073(Orphan nuclear receptor, NURR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1OVL|rcsb pdb:5Y41|rcsb pdb:5YD6|rcsb pdb:6DDA|rcsb pdb:6L6L|rcsb pdb:6L6Q|reactome:R-HSA-383280|reactome:R-HSA-4090294|refseq:XP_016859708.1|entrezgene/locuslink:4929(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rogid:UfmVN3sNbuzJ5/45K3gIFICfco49606 rigid:eBg4620lcSiTdJL36vzdp1T40Fo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:P28702 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680206|imex:IM-28774-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:ShQxqW4BpaAXDi3p5nFD97G6c5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:P28702 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680198|imex:IM-28774-773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:ShQxqW4BpaAXDi3p5nFD97G6c5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19793 uniprotkb:P37231 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680190|imex:IM-28774-1685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|entrezgene/locuslink:6256(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:Afz45NigykVUd0DZqgwc+ulUMqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:Q15699 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-750671|uniprotkb:Q546C8|uniprotkb:Q96FH4|ensembl:ENSP00000315417 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:alx1_human(display_long)|uniprotkb:CART1(gene name synonym)|uniprotkb:Cartilage homeoprotein 1(gene name synonym)|uniprotkb:ALX1(gene name)|psi-mi:ALX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680182|imex:IM-28774-1263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_008913.2|ensembl:ENSG00000180318(gene)|ensembl:ENST00000316824(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016604"(nuclear body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033209|entrezgene/locuslink:8092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:nRWF8JJMf+A+8KBUi3H0AQzTqqA9606 rigid:0yAe58NZkHhssb/RXfyXVFvn4HY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:P48431 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680174|imex:IM-28774-2159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944|entrezgene/locuslink:6657(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rigid:B/2UnCHySfpFs8u72Qpwq1uqTiA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:Q9H161 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680158|imex:IM-28774-771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rigid:NrWVqNDWRz3qlSnU5BdZuGNb07g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:P31249 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680150|imex:IM-28774-3425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1|entrezgene/locuslink:3232(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606 rigid:prddCOaYf+1+BqREIDmnmDTKBho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:P17509 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-741308|ensembl:ENSP00000225648|ensembl:ENSP00000420009|uniprotkb:P09068|uniprotkb:Q9HB11|uniprotkb:Q9UGH2|uniprotkb:A8K835|uniprotkb:D3DTV5 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:hxb6_human(display_long)|uniprotkb:Homeobox protein Hox-2B(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein Hu-2(gene name synonym)|uniprotkb:HOXB6(gene name)|psi-mi:HOXB6(display_short)|uniprotkb:HOX2B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680142|imex:IM-28774-2155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P17509|ensembl:ENSG00000108511(gene)|ensembl:ENST00000225648(transcript)|ensembl:ENST00000484302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_061825.2|refseq:XP_005257340.1|refseq:XP_005257341.1|entrezgene/locuslink:3216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:5MTUEA03jhudRW4zALviuhMFPPc9606 rigid:B3J8dD+Bubrj4gGjQUbRM1mIYac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:O43365 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-8643838|ensembl:ENSP00000324884|ensembl:ENSP00000379640|ensembl:ENSP00000484411|uniprotkb:A4D181|intact:MINT-8163379 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:hxa3_human(display_long)|uniprotkb:HOXA3(gene name)|psi-mi:HOXA3(display_short)|uniprotkb:HOX1E(gene name synonym)|uniprotkb:Homeobox protein Hox-1E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680134|imex:IM-28774-2153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) ensembl:ENSG00000105997(gene)|ensembl:ENST00000317201(transcript)|ensembl:ENST00000396352(transcript)|ensembl:ENST00000612286(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0010467"(gene expression)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0048538"(thymus development)|go:"GO:0048645"(animal organ formation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0071837"(HMG box domain binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011513645.1|refseq:XP_005249787.1|refseq:XP_005249788.1|refseq:XP_005249789.1|refseq:NP_109377.1|refseq:NP_705895.1|refseq:XP_006715778.1|entrezgene/locuslink:3200(identity) - - comment:mint figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:7gP6b03wtjUhsVpcwdjdrUtQj4Y9606 rigid:t7JUaCkMsV4q9h/R5Ku3jpo8FKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:P55318 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-3910364|uniprotkb:A9LYI5|uniprotkb:Q53F16|uniprotkb:Q9UMW9|ensembl:ENSP00000304004 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:foxa3_human(display_long)|uniprotkb:FOXA3(gene name)|psi-mi:FOXA3(display_short)|uniprotkb:HNF3G(gene name synonym)|uniprotkb:TCF3G(gene name synonym)|uniprotkb:Fork head-related protein FKH H3(gene name synonym)|uniprotkb:Forkhead box protein A3(gene name synonym)|uniprotkb:Transcription factor 3G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680126|imex:IM-28774-1683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_004488.2|ensembl:ENSG00000170608(gene)|ensembl:ENST00000302177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1VTN|reactome:R-HSA-210745|entrezgene/locuslink:3171(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:n02J7Tp+VDpup25KyiVjbGur1Sg9606 rigid:+L5lCVTHeKlHxnlvMFjsBWuET9I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:P55318 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-3910364|uniprotkb:A9LYI5|uniprotkb:Q53F16|uniprotkb:Q9UMW9|ensembl:ENSP00000304004 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:foxa3_human(display_long)|uniprotkb:FOXA3(gene name)|psi-mi:FOXA3(display_short)|uniprotkb:HNF3G(gene name synonym)|uniprotkb:TCF3G(gene name synonym)|uniprotkb:Fork head-related protein FKH H3(gene name synonym)|uniprotkb:Forkhead box protein A3(gene name synonym)|uniprotkb:Transcription factor 3G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680118|imex:IM-28774-769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_004488.2|ensembl:ENSG00000170608(gene)|ensembl:ENST00000302177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1VTN|reactome:R-HSA-210745|entrezgene/locuslink:3171(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:n02J7Tp+VDpup25KyiVjbGur1Sg9606 rigid:+L5lCVTHeKlHxnlvMFjsBWuET9I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:P43694 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-7049352|uniprotkb:B7ZKZ4|ensembl:ENSP00000334458|ensembl:ENSP00000482268|ensembl:ENSP00000495511|uniprotkb:Q5IFM8|intact:MINT-3379484|uniprotkb:Q3MJ45|uniprotkb:B7ZKX0 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:gata4_human(display_long)|uniprotkb:GATA4(gene name)|psi-mi:GATA4(display_short)|uniprotkb:GATA-binding factor 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680110|imex:IM-28774-1261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_001295022.1|refseq:XP_011542119.1|refseq:XP_011542120.1|ensembl:ENSG00000136574(gene)|ensembl:ENSG00000285109(gene)|ensembl:ENST00000335135(transcript)|ensembl:ENST00000622443(transcript)|ensembl:ENST00000647274(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0033189"(response to vitamin A)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|mint:P43694|rcsb pdb:2M9W|reactome:R-HSA-2032785|reactome:R-HSA-400511|reactome:R-HSA-5578768|reactome:R-HSA-9690406|reactome:R-HSA-983231|refseq:XP_016868801.1|refseq:NP_002043.2|refseq:XP_005272442.1|refseq:XP_005272443.1|refseq:XP_006716311.1|entrezgene/locuslink:2626(identity) - - function:"Defects in GATA4 are the cause of atrial septal defect type 2 (ASD2) [MIM:607941]. ASD2 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. ASD2 patients show other heart abnormalities including ventricular and atrioventricular septal defects, pulmonary valve thickening or insufficiency of the cardiac valves. ASD2 is not associated with defects in the cardiac conduction system or non-cardiac abnormalities"|comment:mint|function:Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:lzfeBDLcKGZXrcnJzaVRQrJnfpE9606 rigid:mWQdIy0nA3rP92Hr9qAXL/fk9Sc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:Q04741 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680102|imex:IM-28774-2151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rigid:8pEMVk7AoOyVgorU47uNER/zuzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:Q15744 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680094|imex:IM-28774-767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:D6b0OmrVQFvf8c8W9yH/swb3aUQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H161 uniprotkb:Q92826 intact:EBI-11317841|uniprotkb:Q9HAY9|uniprotkb:Q9H198|uniprotkb:Q96JN7|ensembl:ENSP00000498217 intact:EBI-11317274|uniprotkb:Q96QM4|uniprotkb:Q99810|uniprotkb:B2R878|ensembl:ENSP00000290295 psi-mi:alx4_human(display_long)|uniprotkb:KIAA1788(gene name synonym)|uniprotkb:ALX4(gene name)|psi-mi:ALX4(display_short) psi-mi:hxb13_human(display_long)|uniprotkb:HOXB13(gene name)|psi-mi:HOXB13(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680086|imex:IM-28774-2585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068745.2|ensembl:ENSG00000052850(gene)|ensembl:ENST00000652299(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|rcsb pdb:2M0C|entrezgene/locuslink:60529(identity) refseq:NP_006352.2|ensembl:ENSG00000159184(gene)|ensembl:ENST00000290295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009611"(response to wounding)|go:"GO:0033574"(response to testosterone)|go:"GO:0040008"(regulation of growth)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2CRA|rcsb pdb:5EDN|rcsb pdb:5EEA|rcsb pdb:5EF6|rcsb pdb:5EG0|rcsb pdb:5EGO|rcsb pdb:5NO6|entrezgene/locuslink:10481(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DaXVOOhuuqo/UrD1vbC4d6xNYV49606 rogid:1SnzRAM4GtQSqYfsGf209weqvyw9606 rigid:ZXujt4xIbVyxWQdbmztcz9kZ2xg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZN2 uniprotkb:Q15633 intact:EBI-20862993|ensembl:ENSP00000362979|ensembl:ENSP00000362981|ensembl:ENSP00000453773|ensembl:ENSP00000481787|ensembl:ENSP00000498657|uniprotkb:B2R9U3|uniprotkb:E1P5T9|uniprotkb:H0YNI0 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:tgif2_human(display_long)|uniprotkb:5'-TG-3'-interacting factor 2(gene name synonym)|uniprotkb:TGF-beta-induced transcription factor 2(gene name synonym)|uniprotkb:TGIF2(gene name)|psi-mi:TGIF2(display_short) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680078|imex:IM-28774-3423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000118707(gene)|ensembl:ENST00000373872(transcript)|ensembl:ENST00000373874(transcript)|ensembl:ENST00000560025(transcript)|ensembl:ENST00000611732(transcript)|ensembl:ENST00000650844(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|reactome:R-HSA-2173795|reactome:R-HSA-2173796|refseq:NP_001186442.1|refseq:NP_001186443.1|refseq:NP_001186444.1|refseq:NP_068581.1|entrezgene/locuslink:60436(identity) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:zOCoCajsh2Vddz7FbfnRdxoqKng9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:2ixVdm2DRuSJT8aCi4o2FHwPjoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48380 uniprotkb:P55347 intact:EBI-742557|uniprotkb:Q5JTL7|uniprotkb:Q5JTL8|uniprotkb:Q6NW13|uniprotkb:Q8WTU4|uniprotkb:Q95HL5|uniprotkb:Q95HL6|uniprotkb:A8K0H5|uniprotkb:D3DRH8|uniprotkb:D3DRH9|ensembl:ENSP00000371434|ensembl:ENSP00000482598 intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547 psi-mi:rfx3_human(display_long)|uniprotkb:Regulatory factor X 3(gene name synonym)|uniprotkb:RFX3(gene name)|psi-mi:RFX3(display_short) psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680070|imex:IM-28774-3421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002910.1|refseq:NP_602304.1|refseq:NP_001269045.1|refseq:NP_001269046.1|ensembl:ENSG00000080298(gene)|ensembl:ENST00000382004(transcript)|ensembl:ENST00000617270(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|entrezgene/locuslink:5991(identity) refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472|entrezgene/locuslink:5316(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZaJnW0P0U9zhzPKADzUpbtwJptI9606 rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606 rigid:5xda/DzrlDimuY+f/6KH8L4vr1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48380 uniprotkb:O14896 intact:EBI-742557|uniprotkb:Q5JTL7|uniprotkb:Q5JTL8|uniprotkb:Q6NW13|uniprotkb:Q8WTU4|uniprotkb:Q95HL5|uniprotkb:Q95HL6|uniprotkb:A8K0H5|uniprotkb:D3DRH8|uniprotkb:D3DRH9|ensembl:ENSP00000371434|ensembl:ENSP00000482598 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:rfx3_human(display_long)|uniprotkb:Regulatory factor X 3(gene name synonym)|uniprotkb:RFX3(gene name)|psi-mi:RFX3(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680062|imex:IM-28774-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002910.1|refseq:NP_602304.1|refseq:NP_001269045.1|refseq:NP_001269046.1|ensembl:ENSG00000080298(gene)|ensembl:ENST00000382004(transcript)|ensembl:ENST00000617270(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|entrezgene/locuslink:5991(identity) refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|entrezgene/locuslink:3664(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZaJnW0P0U9zhzPKADzUpbtwJptI9606 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:RTEZXH4NJaBYMA1OtRJlxY2GhZU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48380 uniprotkb:O00499 intact:EBI-742557|uniprotkb:Q5JTL7|uniprotkb:Q5JTL8|uniprotkb:Q6NW13|uniprotkb:Q8WTU4|uniprotkb:Q95HL5|uniprotkb:Q95HL6|uniprotkb:A8K0H5|uniprotkb:D3DRH8|uniprotkb:D3DRH9|ensembl:ENSP00000371434|ensembl:ENSP00000482598 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:rfx3_human(display_long)|uniprotkb:Regulatory factor X 3(gene name synonym)|uniprotkb:RFX3(gene name)|psi-mi:RFX3(display_short) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680054|imex:IM-28774-2149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002910.1|refseq:NP_602304.1|refseq:NP_001269045.1|refseq:NP_001269046.1|ensembl:ENSG00000080298(gene)|ensembl:ENST00000382004(transcript)|ensembl:ENST00000617270(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|entrezgene/locuslink:5991(identity) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N|entrezgene/locuslink:274(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZaJnW0P0U9zhzPKADzUpbtwJptI9606 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:JVd8t1ex6Lv+SOTdojpLqUtfUmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96RU7 uniprotkb:P18848 intact:EBI-492476|uniprotkb:Q53GU4|uniprotkb:Q53ZW7|uniprotkb:Q6I9Y9|uniprotkb:Q8TAI6|uniprotkb:Q9H5M8|uniprotkb:Q9NUD2|ensembl:ENSP00000217233 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:trib3_human(display_long)|uniprotkb:Neuronal cell death-inducible putative kinase(gene name synonym)|uniprotkb:p65-interacting inhibitor of NF-kappa-B(gene name synonym)|uniprotkb:SINK(gene name synonym)|uniprotkb:TRIB3(gene name)|psi-mi:TRIB3(display_short)|uniprotkb:C20orf97(gene name synonym)|uniprotkb:NIPK(gene name synonym)|uniprotkb:SKIP3(gene name synonym)|uniprotkb:TRB3(gene name synonym) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26679926|imex:IM-28774-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066981.2|refseq:NP_001288117.1|refseq:NP_001288119.1|refseq:NP_001288122.1|refseq:NP_001288125.1|refseq:NP_001288130.1|ensembl:ENSG00000101255(gene)|ensembl:ENST00000217233(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0055106"(ubiquitin-protein transferase regulator activity)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024104|interpro:IPR024106|mint:Q96RU7|reactome:R-HSA-1257604|reactome:R-HSA-165158|reactome:R-HSA-1989781|reactome:R-HSA-199418|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-9633012|reactome:R-HSA-9648895|entrezgene/locuslink:57761(identity) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity) - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GdgLSuvRzwm30QECRXSbpr2IIPM9606 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:sxeaw9DygfH5dpmdtKplpibNmPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VDQ8 uniprotkb:Q05BA5 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680480|imex:IM-28774-785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:r+Oov06nZe7kild4dmNqTrAi3N0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VDQ8 uniprotkb:Q61545 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680472|imex:IM-28774-1265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:XnP9Ywzvnd+z6qClBUDkj0rEXjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ER75 uniprotkb:Q04744 intact:EBI-26680434|ensembl:ENSMUSP00000127446|uniprotkb:A1L3D2|uniprotkb:E9Q2V2 intact:EBI-26673795|ensembl:ENSMUSP00000053361|uniprotkb:G3X9A6|uniprotkb:Q80UE7 psi-mi:irx6_mouse(display_long)|uniprotkb:Homeodomain protein IRXB3(gene name synonym)|uniprotkb:Iroquois homeobox protein 6(gene name synonym)|uniprotkb:Irx6(gene name)|psi-mi:Irx6(display_short)|uniprotkb:Irxb3(gene name synonym) psi-mi:emx2_mouse(display_long)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym)|uniprotkb:Emx2(gene name)|psi-mi:Emx2(display_short)|uniprotkb:Emx-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680464|imex:IM-28774-783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031738(gene)|ensembl:ENSMUST00000167261(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009584"(detection of visible light)|go:"GO:0010842"(retina layer formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048468"(cell development)|go:"GO:0060040"(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003893(Iroquois-class homeodomain protein)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001288066.1|entrezgene/locuslink:64379(identity) ensembl:ENSMUSG00000043969(gene)|ensembl:ENSMUST00000062216(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034262.2|entrezgene/locuslink:13797(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Xr3MvFCt5YRI9l8+WvQPY20RhrY10090 rogid:K3i+Zeai93MikBwJdzf940evg0I10090 rigid:FJekySoTuSJGAVZp/VXVOoPuqlk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BYH8 uniprotkb:Q00653 intact:EBI-3939694|uniprotkb:Q8NAZ8|uniprotkb:D3DN54|uniprotkb:Q8IUL4|uniprotkb:B3KNR2|ensembl:ENSP00000325663 intact:EBI-307326|uniprotkb:Q04860|uniprotkb:Q9BU75|uniprotkb:Q9H471|uniprotkb:Q9H472|uniprotkb:D3DR83|intact:EBI-28985232|ensembl:ENSP00000358983|ensembl:ENSP00000499294|uniprotkb:A8K9D9 psi-mi:ikbz_human(display_long)|uniprotkb:NFKBIZ(gene name)|psi-mi:NFKBIZ(display_short)|uniprotkb:IKBZ(gene name synonym)|uniprotkb:INAP(gene name synonym)|uniprotkb:MAIL(gene name synonym)|uniprotkb:I-kappa-B-zeta(gene name synonym)|uniprotkb:IL-1 inducible nuclear ankyrin-repeat protein(gene name synonym)|uniprotkb:Molecule possessing ankyrin repeats induced by lipopolysaccharide(gene name synonym) psi-mi:nfkb2_human(display_long)|uniprotkb:NFKB2(gene name)|psi-mi:NFKB2(display_short)|uniprotkb:LYT10(gene name synonym)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:H2TF1(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym)|uniprotkb:Oncogene Lyt-10(gene name synonym)|uniprotkb:Lymphocyte translocation chromosome 10 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680426|imex:IM-28774-3013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144802(gene)|ensembl:ENST00000326172(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006954"(inflammatory response)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001005474.1|refseq:NP_113607.1|entrezgene/locuslink:64332(identity) refseq:NP_001070962.1|refseq:NP_002493.3|refseq:NP_001248332.1|ensembl:ENSG00000077150(gene)|ensembl:ENST00000369966(transcript)|ensembl:ENST00000661543(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|interpro:IPR020683|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q00653|rcsb pdb:1A3Q|rcsb pdb:2D96|go:"GO:0048511"(rhythmic process)|rcsb pdb:3DO7|rcsb pdb:4OT9|rcsb pdb:5ZMC|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-3214841|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-5603029|interpro:IPR002909(Cell surface receptor IPT/TIG)|reactome:R-HSA-5607761|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|reactome:R-HSA-5676590|interpro:IPR011539(Rel homology)|reactome:R-HSA-844456|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|reactome:R-HSA-933542|reactome:R-HSA-9660826|refseq:NP_001275653.1|ensembl:ENST00000189444|ensembl:ENSP00000189444|ensembl:ENSP00000358983|ensembl:ENST00000428099|ensembl:ENSP00000410256|ensembl:ENST00000652277|ensembl:ENSP00000498308|ensembl:ENSP00000499294|refseq:NP_001309863.1|refseq:NP_001309864.1|dip:DIP-24239N|dip:DIP-27535N|entrezgene/locuslink:4791(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4Q01iPxBlPYyeqt9vl5RBxiiXvs9606 rogid:bGZ4DuEhX8eCNtkuMCJnh8PCcEI9606 rigid:UlsoW0AX9O0eZ5SYrodPjY+VFvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64732 uniprotkb:Q8CB77 intact:EBI-26680374|ensembl:ENSMUSP00000096197|uniprotkb:O08753|uniprotkb:Q2M2M4 intact:EBI-6094632|uniprotkb:Q3UI38|uniprotkb:Q80VB2|uniprotkb:Q9R0Q5|ensembl:ENSMUSP00000030427 psi-mi:foxb1_mouse(display_long)|uniprotkb:Transcription factor FKH-5(gene name synonym)|uniprotkb:Foxb1(gene name)|psi-mi:Foxb1(display_short)|uniprotkb:Fkh5(gene name synonym)|uniprotkb:Foxb1a(gene name synonym)|uniprotkb:Foxb1b(gene name synonym)|uniprotkb:Mf3(gene name synonym) psi-mi:eloa1_mouse(display_long)|uniprotkb:Eloa(gene name)|psi-mi:Eloa(display_short)|uniprotkb:Elongin 110 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit A1(gene name synonym)|uniprotkb:SIII p110(gene name synonym)|uniprotkb:Tceb3(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680418|imex:IM-28774-3011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000059246(gene)|ensembl:ENSMUST00000071281(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007412"(axon target recognition)|go:"GO:0007595"(lactation)|go:"GO:0008542"(visual learning)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021510"(spinal cord development)|go:"GO:0021767"(mammillary body development)|go:"GO:0021794"(thalamus development)|go:"GO:0021855"(hypothalamus cell migration)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0033504"(floor plate development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061374"(mammillothalamic axonal tract development)|go:"GO:0061377"(mammary gland lobule development)|go:"GO:0061379"(inferior colliculus development)|go:"GO:0061381"(cell migration in diencephalon)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_071773.2|entrezgene/locuslink:64290(identity) refseq:NP_038764.2|ensembl:ENSMUSG00000028668(gene)|ensembl:ENSMUST00000030427(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0070449"(elongin complex)|go:"GO:0090734"(site of DNA damage)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR010684(RNA polymerase II transcription factor SIII, subunit A)|interpro:IPR017923|interpro:IPR035441|mint:Q8CB77|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|entrezgene/locuslink:27224(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iRyMj8cjgnXgml+BWIuPaJwaEzQ10090 rogid:kQcIpkpxBQd614FnBELoMENjOAw10090 rigid:rQQY/KE7c7aZmmPRxgy8uhjK1Hc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96LW9 uniprotkb:P35638 intact:EBI-21886306|ensembl:ENSP00000345339|ensembl:ENSP00000380050|ensembl:ENSP00000390076|ensembl:ENSP00000413705|uniprotkb:Q8WWS5|uniprotkb:Q6P178 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:zsc31_human(display_long)|uniprotkb:Zinc finger protein 323(gene name synonym)|uniprotkb:ZSCAN31(gene name)|psi-mi:ZSCAN31(display_short)|uniprotkb:ZNF310P(gene name synonym)|uniprotkb:ZNF323(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680366|imex:IM-28774-3433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|ensembl:ENST00000344279(transcript)|ensembl:ENST00000396838(transcript)|ensembl:ENST00000414429(transcript)|ensembl:ENST00000439158(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|ensembl:ENSG00000235109(gene)|refseq:NP_001128687.1|refseq:NP_001128688.1|refseq:NP_001230170.1|refseq:NP_001230171.1|refseq:NP_001230172.1|refseq:NP_001230173.1|refseq:NP_112161.3|refseq:NP_665916.1|refseq:XP_005249352.1|refseq:XP_005249353.1|refseq:XP_011513109.1|refseq:XP_011513110.1|refseq:XP_011513111.1|refseq:XP_011513113.1|refseq:XP_011513114.1|refseq:XP_011513115.1|refseq:XP_016866685.1|entrezgene/locuslink:64288(identity) refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity) - - crc64:31905293FB1FBBE2 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YT7OXWCUpQEhySjV9cajVOh0wfk9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:puuMNvEbAK5DqxnwHESf7YYi3v0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96KN3 uniprotkb:P40424 intact:EBI-2692890|uniprotkb:Q63HL6|uniprotkb:Q86XD1|uniprotkb:B7Z5I5|uniprotkb:F5GZ15|ensembl:ENSP00000298282 intact:EBI-301611|uniprotkb:Q5T488|ensembl:ENSP00000405890|uniprotkb:B4DSC1|uniprotkb:F5H4U9 psi-mi:pknx2_human(display_long)|uniprotkb:PREP2(gene name synonym)|uniprotkb:Homeobox protein PREP-2(gene name synonym)|uniprotkb:PBX/knotted homeobox 2(gene name synonym)|uniprotkb:PKNOX2(gene name)|psi-mi:PKNOX2(display_short) psi-mi:pbx1_human(display_long)|uniprotkb:PBX1(gene name)|psi-mi:PBX1(display_short)|uniprotkb:PRL(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym)|uniprotkb:Homeobox protein PRL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680302|imex:IM-28774-3427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071345.2|refseq:XP_011541246.1|refseq:XP_011541247.1|ensembl:ENSP00000298282|refseq:XP_005271699.1|ensembl:ENSG00000165495(gene)|ensembl:ENST00000298282(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051015"(actin filament binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|refseq:XP_016873599.1|entrezgene/locuslink:63876(identity) refseq:NP_001191892.1|refseq:NP_002576.1|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:1B72|go:"GO:0005634"(nucleus)|rcsb pdb:1PUF|reactome:R-HSA-452723|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|reactome:R-HSA-5617472|reactome:R-HSA-9013508|ensembl:ENSG00000185630(gene)|ensembl:ENST00000420696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|refseq:XP_005245286.1|entrezgene/locuslink:5087(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xeaCbYA1G3WgDVcHtnhzgoSe/FI9606 rogid:YViNj+q9A6e+VCAkMUQowMzvowE9606 rigid:0eGrkV3DlpfqZcAlLVCwK6e9Zx4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV8 uniprotkb:O43439 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680350|imex:IM-28774-3431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rigid:PXrCNAHlZPt1CXP32ClIpVRzdHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV8 uniprotkb:Q06455 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-743342|uniprotkb:O14784|uniprotkb:Q06456|uniprotkb:Q14873|uniprotkb:Q16239|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q6IBL1|uniprotkb:Q92479|uniprotkb:Q9BRZ0|ensembl:ENSP00000265814|ensembl:ENSP00000428543|ensembl:ENSP00000481112|ensembl:ENSP00000481315|ensembl:ENSP00000481799|uniprotkb:B7Z4P4|uniprotkb:E7EPN4|uniprotkb:Q6NXH1|uniprotkb:Q7Z4J5 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:mtg8_human(display_long)|uniprotkb:Protein MTG8(gene name synonym)|uniprotkb:Protein ETO(gene name synonym)|uniprotkb:Eight twenty one protein(gene name synonym)|uniprotkb:Cyclin-D-related protein(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 2(gene name synonym)|uniprotkb:RUNX1T1(gene name)|psi-mi:RUNX1T1(display_short)|uniprotkb:AML1T1(gene name synonym)|uniprotkb:CBFA2T1(gene name synonym)|uniprotkb:CDR(gene name synonym)|uniprotkb:ETO(gene name synonym)|uniprotkb:MTG8(gene name synonym)|uniprotkb:ZMYND2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680342|imex:IM-28774-3429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) refseq:NP_001185554.1|refseq:NP_001185555.1|refseq:NP_001185556.1|refseq:NP_001185557.1|refseq:NP_001185558.1|refseq:NP_001185559.1|refseq:NP_001185560.1|refseq:NP_001185561.1|refseq:NP_004340.1|refseq:NP_783552.1|refseq:NP_783553.1|refseq:NP_783554.1|ensembl:ENSG00000079102(gene)|ensembl:ENST00000265814(transcript)|ensembl:ENST00000523629(transcript)|ensembl:ENST00000613302(transcript)|ensembl:ENST00000614812(transcript)|ensembl:ENST00000617740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|refseq:XP_011515653.1|refseq:XP_011515654.1|refseq:XP_011515655.1|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:Q06455|rcsb pdb:1WQ6|rcsb pdb:2DJ8|rcsb pdb:2H7B|rcsb pdb:2KNH|rcsb pdb:2KYG|rcsb pdb:2OD1|rcsb pdb:2ODD|rcsb pdb:2PP4|rcsb pdb:4JOL|refseq:NP_001185563.1|refseq:NP_001185562.1|refseq:NP_001185608.1|refseq:XP_006716739.1|refseq:XP_016869420.1|refseq:XP_016869421.1|refseq:XP_016869422.1|refseq:XP_016869423.1|refseq:XP_016869424.1|refseq:XP_016869425.1|refseq:XP_016869426.1|dip:DIP-29401N|entrezgene/locuslink:862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:SMomKOZSbtqhKiAkkUkabKbC8/09606 rigid:xiYOpDR2zhd9TNYIzf3RWC8Vjxw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV8 uniprotkb:Q06455 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-743342|uniprotkb:O14784|uniprotkb:Q06456|uniprotkb:Q14873|uniprotkb:Q16239|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q6IBL1|uniprotkb:Q92479|uniprotkb:Q9BRZ0|ensembl:ENSP00000265814|ensembl:ENSP00000428543|ensembl:ENSP00000481112|ensembl:ENSP00000481315|ensembl:ENSP00000481799|uniprotkb:B7Z4P4|uniprotkb:E7EPN4|uniprotkb:Q6NXH1|uniprotkb:Q7Z4J5 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:mtg8_human(display_long)|uniprotkb:Protein MTG8(gene name synonym)|uniprotkb:Protein ETO(gene name synonym)|uniprotkb:Eight twenty one protein(gene name synonym)|uniprotkb:Cyclin-D-related protein(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 2(gene name synonym)|uniprotkb:RUNX1T1(gene name)|psi-mi:RUNX1T1(display_short)|uniprotkb:AML1T1(gene name synonym)|uniprotkb:CBFA2T1(gene name synonym)|uniprotkb:CDR(gene name synonym)|uniprotkb:ETO(gene name synonym)|uniprotkb:MTG8(gene name synonym)|uniprotkb:ZMYND2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680334|imex:IM-28774-2167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) refseq:NP_001185554.1|refseq:NP_001185555.1|refseq:NP_001185556.1|refseq:NP_001185557.1|refseq:NP_001185558.1|refseq:NP_001185559.1|refseq:NP_001185560.1|refseq:NP_001185561.1|refseq:NP_004340.1|refseq:NP_783552.1|refseq:NP_783553.1|refseq:NP_783554.1|ensembl:ENSG00000079102(gene)|ensembl:ENST00000265814(transcript)|ensembl:ENST00000523629(transcript)|ensembl:ENST00000613302(transcript)|ensembl:ENST00000614812(transcript)|ensembl:ENST00000617740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|refseq:XP_011515653.1|refseq:XP_011515654.1|refseq:XP_011515655.1|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:Q06455|rcsb pdb:1WQ6|rcsb pdb:2DJ8|rcsb pdb:2H7B|rcsb pdb:2KNH|rcsb pdb:2KYG|rcsb pdb:2OD1|rcsb pdb:2ODD|rcsb pdb:2PP4|rcsb pdb:4JOL|refseq:NP_001185563.1|refseq:NP_001185562.1|refseq:NP_001185608.1|refseq:XP_006716739.1|refseq:XP_016869420.1|refseq:XP_016869421.1|refseq:XP_016869422.1|refseq:XP_016869423.1|refseq:XP_016869424.1|refseq:XP_016869425.1|refseq:XP_016869426.1|dip:DIP-29401N|entrezgene/locuslink:862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:SMomKOZSbtqhKiAkkUkabKbC8/09606 rigid:xiYOpDR2zhd9TNYIzf3RWC8Vjxw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV8 uniprotkb:Q02535 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680326|imex:IM-28774-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rigid:HsRGXQz3etikMrwMkr4xR0BshIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00978 uniprotkb:Q8IXT2 intact:EBI-626526|ensembl:ENSP00000380073|ensembl:ENSP00000494792|uniprotkb:D3DS61 intact:EBI-3921202|ensembl:ENSP00000269945|uniprotkb:Q96M39|uniprotkb:Q96SD4|uniprotkb:Q8N6Q2 psi-mi:irf9_human(display_long)|uniprotkb:Transcriptional regulator ISGF3 subunit gamma(gene name synonym)|uniprotkb:IFN-alpha-responsive transcription factor subunit(gene name synonym)|uniprotkb:Interferon-stimulated gene factor 3 gamma(gene name synonym)|uniprotkb:ISGF3 p48 subunit(gene name synonym)|uniprotkb:IRF9(gene name)|psi-mi:IRF9(display_short)|uniprotkb:ISGF3G(gene name synonym) psi-mi:dmrtd_human(display_long)|uniprotkb:DMRTC2(gene name)|psi-mi:DMRTC2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680318|imex:IM-28774-781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000213928(gene)|ensembl:ENSG00000285048(gene)|ensembl:ENST00000396864(transcript)|ensembl:ENST00000646071(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|refseq:NP_006075.3|entrezgene/locuslink:10379(identity) ensembl:ENSG00000142025(gene)|ensembl:ENST00000269945(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|refseq:NP_001035373.1|entrezgene/locuslink:63946(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8FfmT/MiSW3eIxCL2ip5OSXyKyE9606 rogid:qE8QmzO1f6C8daX9E6vxN7zfC8w9606 rigid:OmWeZSNPhpQBpqLMExq2u4QhV+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NU02 uniprotkb:Q9BWW4 intact:EBI-8464238|uniprotkb:B3KUQ0|intact:MINT-8417601|uniprotkb:Q9H6Y9|ensembl:ENSP00000367644|ensembl:ENSP00000367631 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 psi-mi:anke1_human(display_long)|uniprotkb:ANKEF1(gene name)|psi-mi:ANKEF1(display_short)|uniprotkb:ANKRD5(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 5(gene name synonym) psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680310|imex:IM-28774-2165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290401.1|refseq:NP_942093.1|refseq:NP_071379.3|ensembl:ENST00000378380(transcript)|ensembl:ENST00000378392(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002110(Ankyrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR020683|interpro:IPR036770|mint:Q9NU02|ensembl:ENSG00000132623(gene)|entrezgene/locuslink:63926(identity) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4|entrezgene/locuslink:23648(identity) - comment:mint|comment:homomint crc64:DBBB169D4EE10536 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8itXXhb3BHe7mX9ll6kIt7Wacso9606 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rigid:2jil0IsHBvAcDfeMVbHfUBBQ0BI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZV8 uniprotkb:O43439 intact:EBI-3957793|ensembl:ENSP00000276594|uniprotkb:Q86UX9 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 psi-mi:prd14_human(display_long)|uniprotkb:PRDM14(gene name)|psi-mi:PRDM14(display_short)|uniprotkb:PR domain-containing protein 14(gene name synonym) psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680358|imex:IM-28774-2589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147596(gene)|ensembl:ENST00000276594(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001708"(cell fate specification)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034972"(histone H3-R26 methylation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0060817"(inactivation of paternal X chromosome)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044408|reactome:R-HSA-452723|go:"GO:0044030"(regulation of DNA methylation)|refseq:NP_078780.1|dip:DIP-58143N|entrezgene/locuslink:63978(identity) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:b2ZxgQD3iSt29oDadwHRce+Cnz09606 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rigid:PXrCNAHlZPt1CXP32ClIpVRzdHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05423 uniprotkb:P27695 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979 psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680703|imex:IM-28774-793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N|entrezgene/locuslink:328(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606 rigid:D4lzSRO3wpxFnPvBfHqCdsCjsCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05423 uniprotkb:P18847 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680711|imex:IM-28774-2593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N|entrezgene/locuslink:467(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rigid:c/AFuOBVOZkmeB9TlSMZaRcXXH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BV97 uniprotkb:Q9UMX1 intact:EBI-4395497|uniprotkb:A8K827|uniprotkb:B7WNU3|uniprotkb:Q59FB4|uniprotkb:Q96NW0|ensembl:ENSP00000252799 intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918 psi-mi:zn747_human(display_long)|uniprotkb:ZNF747(gene name)|psi-mi:ZNF747(display_short) psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680687|imex:IM-28774-1271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076420.1|refseq:NP_001291947.1|refseq:NP_001291948.1|refseq:NP_001291949.1|ensembl:ENSG00000169955(gene)|ensembl:ENST00000252799(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR036051|reactome:R-HSA-212436|entrezgene/locuslink:65988(identity) refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|entrezgene/locuslink:51684(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4ZgUM0HpTJgcARQfmBh37KdS33E9606 rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606 rigid:uR1k0o5VxTJqAHut+28LsJAM74E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TBC5 uniprotkb:P09016 intact:EBI-3919096|intact:EBI-28972493|uniprotkb:Q9H9A0|uniprotkb:Q9BRK7|uniprotkb:B4DG23|uniprotkb:E9PBI0|ensembl:ENSP00000240727|ensembl:ENSP00000468934 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:zsc18_human(display_long)|uniprotkb:ZSCAN18(gene name)|psi-mi:ZSCAN18(display_short)|uniprotkb:ZNF447(gene name synonym)|uniprotkb:Zinc finger protein 447(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680679|imex:IM-28774-3021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000240727|ensembl:ENST00000421612|ensembl:ENSP00000392653|ensembl:ENST00000600404|ensembl:ENSP00000470123|ensembl:ENSP00000468934|refseq:XP_011525540.1|refseq:XP_011525541.1|refseq:NP_001139014.1|refseq:NP_001139015.1|refseq:NP_001139016.1|refseq:NP_076415.3|refseq:XP_006723398.1|refseq:XP_005259231.1|refseq:XP_016882658.1|refseq:XP_016882659.1|refseq:XP_016882660.1|ensembl:ENSG00000121413(gene)|ensembl:ENST00000240727(transcript)|ensembl:ENST00000601144(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|entrezgene/locuslink:65982(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cks+MzbAAvR9z3Ui9+ZctUGpbMM9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:CIJBd5ba8OB/1r5Iold7E2QvQzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14527 uniprotkb:Q01844 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680671|imex:IM-28774-3019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654|entrezgene/locuslink:6596(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:54yLavYDdEjj3sKOBpFbLDA4boE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q9WV72 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-26680645|ensembl:ENSMUSP00000020551|uniprotkb:Q5SSV5 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:asb3_mouse(display_long)|uniprotkb:Asb3(gene name)|psi-mi:Asb3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680663|imex:IM-28774-1697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000020305(gene)|ensembl:ENSMUST00000020551(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037329|refseq:NP_076395.2|refseq:XP_006514834.1|entrezgene/locuslink:65257(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:nZHvNvcF7FjMLl+UCtrdn5ijQQQ10090 rigid:GkJJUbSuE9BQlrT67p6dYsBMkI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WV74 uniprotkb:Q07279 intact:EBI-26680608|ensembl:ENSMUSP00000084054 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:asb1_mouse(display_long)|uniprotkb:Asb1(gene name)|psi-mi:Asb1(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680637|imex:IM-28774-1695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026311(gene)|ensembl:ENSMUST00000086843(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030539"(male genitalia development)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037331|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001034215.1|entrezgene/locuslink:65247(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+DneGFaC9eo1z8z4vTjMr6Nr+ws10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:+teghto2mBGoFEEYxFFwN4P9zrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WV74 uniprotkb:P09632 intact:EBI-26680608|ensembl:ENSMUSP00000084054 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:asb1_mouse(display_long)|uniprotkb:Asb1(gene name)|psi-mi:Asb1(display_short) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680629|imex:IM-28774-3017 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026311(gene)|ensembl:ENSMUST00000086843(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030539"(male genitalia development)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037331|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001034215.1|entrezgene/locuslink:65247(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+DneGFaC9eo1z8z4vTjMr6Nr+ws10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:3d1JVvFntXJtUOqIFSmjeq6AdrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53LP3 uniprotkb:P61457 intact:EBI-8832449|uniprotkb:Q9H6U1|uniprotkb:Q8NE15|intact:EBI-28984067|ensembl:ENSP00000365830 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:swahc_human(display_long)|uniprotkb:ANKRD57(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 57(gene name synonym)|uniprotkb:C2orf26(gene name synonym)|uniprotkb:Protein sosondowah homolog C(gene name synonym)|uniprotkb:SOWAHC(gene name)|psi-mi:SOWAHC(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680600|imex:IM-28774-2169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000365830|refseq:NP_075392.2|ensembl:ENSG00000198142(gene)|interpro:IPR002110(Ankyrin)|ensembl:ENST00000356454(transcript)|interpro:IPR036770|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9035034|interpro:IPR020683|entrezgene/locuslink:65124(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vS+1x75B0YAYo5vOoD/ztQm2pLE9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:x74eL/ZppznntKvbunDMgjUC3Yk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q923B3 uniprotkb:Q9JL10 intact:EBI-26680552|uniprotkb:Q8BS00|uniprotkb:Q9D6I6|uniprotkb:Q9QZ07 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 psi-mi:nrif1_mouse(display_long)|uniprotkb:Neurotrophin receptor-interacting factor(gene name synonym)|uniprotkb:Zinc finger protein 110(gene name synonym)|uniprotkb:Nrif1(gene name)|psi-mi:Nrif1(display_short)|uniprotkb:Nrif(gene name synonym)|uniprotkb:Zfp110(gene name synonym) psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680592|imex:IM-28774-3015 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005166"(neurotrophin p75 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1990009"(retinal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-MMU-212436|refseq:NP_075357.4|refseq:XP_006540338.1|interpro:IPR001909(Krueppel-associated box)|interpro:IPR036051|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:65020(identity) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Cl1syYT79gR+R+wjSF4i4CwcPrc10090 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rigid:DbDoRsRAB5iHs6hdg2Or4wqr7t8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q923B3 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-26680552|uniprotkb:Q8BS00|uniprotkb:Q9D6I6|uniprotkb:Q9QZ07 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:nrif1_mouse(display_long)|uniprotkb:Neurotrophin receptor-interacting factor(gene name synonym)|uniprotkb:Zinc finger protein 110(gene name synonym)|uniprotkb:Nrif1(gene name)|psi-mi:Nrif1(display_short)|uniprotkb:Nrif(gene name synonym)|uniprotkb:Zfp110(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680584|imex:IM-28774-1693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005166"(neurotrophin p75 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1990009"(retinal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-MMU-212436|refseq:NP_075357.4|refseq:XP_006540338.1|interpro:IPR001909(Krueppel-associated box)|interpro:IPR036051|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:65020(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:Cl1syYT79gR+R+wjSF4i4CwcPrc10090 rigid:/pbHVa7BlMpo1iszhVs6hyC3TwA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15475 uniprotkb:O00167 intact:EBI-743675|uniprotkb:Q96H64|uniprotkb:Q53Y16|ensembl:ENSP00000494686 intact:EBI-750211|uniprotkb:Q86U84|uniprotkb:Q5JSW8|uniprotkb:Q96CV6|uniprotkb:Q96H97|uniprotkb:Q99503|uniprotkb:Q99812|uniprotkb:Q9BWF6|uniprotkb:Q9H4S3|uniprotkb:Q9H4S9|uniprotkb:Q9NPZ4|uniprotkb:Q9UIX7|intact:EBI-28973816|ensembl:ENSP00000333640 psi-mi:six1_human(display_long)|uniprotkb:Sine oculis homeobox homolog 1(gene name synonym)|uniprotkb:SIX1(gene name)|psi-mi:SIX1(display_short) psi-mi:eya2_human(display_long)|uniprotkb:EYA2(gene name)|psi-mi:EYA2(display_short)|uniprotkb:EAB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680544|imex:IM-28774-789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005973.1|ensembl:ENSG00000126778(gene)|ensembl:ENST00000645694(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001822"(kidney development)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014857"(regulation of skeletal muscle cell proliferation)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048538"(thymus development)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048699"(generation of neurons)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048839"(inner ear development)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051451"(myoblast migration)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0061055"(myotome development)|go:"GO:0061197"(fungiform papilla morphogenesis)|go:"GO:0061551"(trigeminal ganglion development)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072075"(metanephric mesenchyme development)|interpro:IPR031278|interpro:IPR031701|go:"GO:0072095"(regulation of branch elongation involved in ureteric bud branching)|mint:Q15475|rcsb pdb:4EGC|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:0072172"(mesonephric tubule formation)|go:"GO:0072193"(ureter smooth muscle cell differentiation)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000729"(positive regulation of mesenchymal cell proliferation involved in ureter development)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|dip:DIP-34448N|entrezgene/locuslink:6495(identity) ensembl:ENSP00000333640|ensembl:ENST00000357410|ensembl:ENSP00000349986|ensembl:ENST00000497062|ensembl:ENSP00000417105|refseq:NP_005235.3|refseq:NP_742108.2|dip:DIP-40707N|ensembl:ENSG00000064655(gene)|ensembl:ENST00000327619(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0048856"(anatomical structure development)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR028473|interpro:IPR036412|interpro:IPR038102|interpro:IPR042577|mint:O00167|rcsb pdb:3GEB|rcsb pdb:3HB0|rcsb pdb:3HB1|rcsb pdb:4EGC|rcsb pdb:5ZMA|reactome:R-HSA-5693565|entrezgene/locuslink:2139(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CDsvqBP4KDSbYoxt3Qi/sdP9ivo9606 rogid:GzEF57gMLHQVYIXIpdcf3XffCS49606 rigid:Lf5CTq5OtZmBoIhmmfzcmNXbpLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15475 uniprotkb:O00167 intact:EBI-743675|uniprotkb:Q96H64|uniprotkb:Q53Y16|ensembl:ENSP00000494686 intact:EBI-750211|uniprotkb:Q86U84|uniprotkb:Q5JSW8|uniprotkb:Q96CV6|uniprotkb:Q96H97|uniprotkb:Q99503|uniprotkb:Q99812|uniprotkb:Q9BWF6|uniprotkb:Q9H4S3|uniprotkb:Q9H4S9|uniprotkb:Q9NPZ4|uniprotkb:Q9UIX7|intact:EBI-28973816|ensembl:ENSP00000333640 psi-mi:six1_human(display_long)|uniprotkb:Sine oculis homeobox homolog 1(gene name synonym)|uniprotkb:SIX1(gene name)|psi-mi:SIX1(display_short) psi-mi:eya2_human(display_long)|uniprotkb:EYA2(gene name)|psi-mi:EYA2(display_short)|uniprotkb:EAB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680536|imex:IM-28774-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005973.1|ensembl:ENSG00000126778(gene)|ensembl:ENST00000645694(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001822"(kidney development)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014857"(regulation of skeletal muscle cell proliferation)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048538"(thymus development)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048699"(generation of neurons)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048839"(inner ear development)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0051451"(myoblast migration)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0061055"(myotome development)|go:"GO:0061197"(fungiform papilla morphogenesis)|go:"GO:0061551"(trigeminal ganglion development)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072075"(metanephric mesenchyme development)|interpro:IPR031278|interpro:IPR031701|go:"GO:0072095"(regulation of branch elongation involved in ureteric bud branching)|mint:Q15475|rcsb pdb:4EGC|go:"GO:0072107"(positive regulation of ureteric bud formation)|go:"GO:0072172"(mesonephric tubule formation)|go:"GO:0072193"(ureter smooth muscle cell differentiation)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000729"(positive regulation of mesenchymal cell proliferation involved in ureter development)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|dip:DIP-34448N|entrezgene/locuslink:6495(identity) ensembl:ENSP00000333640|ensembl:ENST00000357410|ensembl:ENSP00000349986|ensembl:ENST00000497062|ensembl:ENSP00000417105|refseq:NP_005235.3|refseq:NP_742108.2|dip:DIP-40707N|ensembl:ENSG00000064655(gene)|ensembl:ENST00000327619(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0048856"(anatomical structure development)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR006545(EYA)|interpro:IPR028472|interpro:IPR028473|interpro:IPR036412|interpro:IPR038102|interpro:IPR042577|mint:O00167|rcsb pdb:3GEB|rcsb pdb:3HB0|rcsb pdb:3HB1|rcsb pdb:4EGC|rcsb pdb:5ZMA|reactome:R-HSA-5693565|entrezgene/locuslink:2139(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CDsvqBP4KDSbYoxt3Qi/sdP9ivo9606 rogid:GzEF57gMLHQVYIXIpdcf3XffCS49606 rigid:Lf5CTq5OtZmBoIhmmfzcmNXbpLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWT3 uniprotkb:Q8N653 intact:EBI-11060140|uniprotkb:Q9H8L2|uniprotkb:Q969N1|uniprotkb:Q59G05|uniprotkb:B2RBH4|uniprotkb:Q9HAD0|ensembl:ENSP00000238714 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:papog_human(display_long)|uniprotkb:PAPOLG(gene name)|psi-mi:PAPOLG(display_short)|uniprotkb:"Neo-poly(A) polymerase"(gene name synonym)|uniprotkb:PAP2(gene name synonym)|uniprotkb:PAPG(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase gamma(gene name synonym)|uniprotkb:SRP RNA 3'-adenylating enzyme(gene name synonym)|uniprotkb:Signal recognition particle RNA-adenylating enzyme(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680528|imex:IM-28774-2591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075045.2|refseq:XP_005264557.1|ensembl:ENSG00000115421(gene)|ensembl:ENST00000238714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR043519|rcsb pdb:4LT6|entrezgene/locuslink:64895(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T753BGfFCqeiN8vUSvhKUH5k2/Y9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:i77M1pWzRGqEU9Tkxpni6k2ycYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWT3 uniprotkb:P61457 intact:EBI-11060140|uniprotkb:Q9H8L2|uniprotkb:Q969N1|uniprotkb:Q59G05|uniprotkb:B2RBH4|uniprotkb:Q9HAD0|ensembl:ENSP00000238714 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:papog_human(display_long)|uniprotkb:PAPOLG(gene name)|psi-mi:PAPOLG(display_short)|uniprotkb:"Neo-poly(A) polymerase"(gene name synonym)|uniprotkb:PAP2(gene name synonym)|uniprotkb:PAPG(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase gamma(gene name synonym)|uniprotkb:SRP RNA 3'-adenylating enzyme(gene name synonym)|uniprotkb:Signal recognition particle RNA-adenylating enzyme(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680520|imex:IM-28774-787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075045.2|refseq:XP_005264557.1|ensembl:ENSG00000115421(gene)|ensembl:ENST00000238714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR043519|rcsb pdb:4LT6|entrezgene/locuslink:64895(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T753BGfFCqeiN8vUSvhKUH5k2/Y9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:CGW/0r2kRBQRJjwdIVKNiYHGoL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BWT3 uniprotkb:P23511 intact:EBI-11060140|uniprotkb:Q9H8L2|uniprotkb:Q969N1|uniprotkb:Q59G05|uniprotkb:B2RBH4|uniprotkb:Q9HAD0|ensembl:ENSP00000238714 intact:EBI-389739|uniprotkb:Q8IXU0|ensembl:ENSP00000345702 psi-mi:papog_human(display_long)|uniprotkb:PAPOLG(gene name)|psi-mi:PAPOLG(display_short)|uniprotkb:"Neo-poly(A) polymerase"(gene name synonym)|uniprotkb:PAP2(gene name synonym)|uniprotkb:PAPG(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase gamma(gene name synonym)|uniprotkb:SRP RNA 3'-adenylating enzyme(gene name synonym)|uniprotkb:Signal recognition particle RNA-adenylating enzyme(gene name synonym) psi-mi:nfya_human(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680512|imex:IM-28774-1691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075045.2|refseq:XP_005264557.1|ensembl:ENSG00000115421(gene)|ensembl:ENST00000238714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR043519|rcsb pdb:4LT6|entrezgene/locuslink:64895(identity) refseq:NP_002496.1|refseq:NP_068351.1|ensembl:ENSG00000001167(gene)|ensembl:ENST00000341376(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001289(CCAAT-binding transcription factor, subunit B)|interpro:IPR018362|rcsb pdb:4AWL|rcsb pdb:6QMP|rcsb pdb:6QMQ|rcsb pdb:6QMS|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|entrezgene/locuslink:4800(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:T753BGfFCqeiN8vUSvhKUH5k2/Y9606 rogid:ZzEyS17rD3653YFSvnBoGdl1T3s9606 rigid:u6r33S1Vk79qJMKPl/SAmdlK0ow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VDQ8 uniprotkb:Q9JL10 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680504|imex:IM-28774-1269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rigid:YIa1qe+u8YsP2vfCYIPBVB2WABM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VDQ8 uniprotkb:O55144 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680496|imex:IM-28774-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:609C1sX1/bt0f/CMtvEZUdHxfRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VDQ8 uniprotkb:Q07279 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680488|imex:IM-28774-1267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:0WGmZgd68iIVfvXl7WTY00ZP36M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:P70662 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680866|imex:IM-28774-3439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:P4A3KOHOuV9LGrJ/1AE5CAi2hno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:P70662 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680858|imex:IM-28774-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:P4A3KOHOuV9LGrJ/1AE5CAi2hno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61372 uniprotkb:Q9CYZ8 intact:EBI-7988215|uniprotkb:P47894|uniprotkb:Q812D8|uniprotkb:P20663|intact:MINT-4594016|ensembl:ENSMUSP00000044879 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:isl1_mouse(display_long)|uniprotkb:Isl1(gene name)|psi-mi:Isl1(display_short) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680850|imex:IM-28774-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067434.3|refseq:XP_006517596.1|ensembl:ENSMUSG00000042258(gene)|ensembl:ENSMUST00000036060(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0048880"(sensory system development)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0007409"(axonogenesis)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0007507"(heart development)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|mint:P61372|rcsb pdb:2RGT|rcsb pdb:4JCJ|interpro:IPR017970|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|entrezgene/locuslink:16392(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - function:Binds to one of the cis-acting domain of the insulin gene enhancer|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd010090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:XYLazKj+KI0xP/TBXecBoHJCNo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:O70220 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-26680815|ensembl:ENSMUSP00000036952|uniprotkb:Q9JJ18 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:foxq1_mouse(display_long)|uniprotkb:HFH-1l(gene name synonym)|uniprotkb:HNF-3/forkhead-like protein 1(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 1(gene name synonym)|uniprotkb:Foxq1(gene name)|psi-mi:Foxq1(display_short)|uniprotkb:Hfh1(gene name synonym)|uniprotkb:Hfh1l(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680842|imex:IM-28774-2599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000038415(gene)|ensembl:ENSMUST00000042118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_032265.3|entrezgene/locuslink:15220(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:5hw+BoKHYlaFQ3k9Z94TikdHwB410090 rigid:FpXuVwXdEnW61+B16+cplOR/c+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01892 uniprotkb:Q15306 intact:EBI-2800992|uniprotkb:Q15359|uniprotkb:A8K9C9|uniprotkb:B4DUG6|ensembl:ENSP00000471921 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 psi-mi:spib_human(display_long)|uniprotkb:SPIB(gene name)|psi-mi:SPIB(display_short) psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680807|imex:IM-28774-2597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000270632|ensembl:ENST00000270632|ensembl:ENSP00000391877|ensembl:ENSP00000471921|ensembl:ENST00000439922|refseq:NP_003112.2|refseq:NP_001230928.1|refseq:NP_001230929.1|refseq:NP_001230927.1|ensembl:ENSG00000269404(gene)|ensembl:ENST00000595883(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036390|interpro:IPR036388|entrezgene/locuslink:6689(identity) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EiWsB4rAy9HjTBy2oDde3sqeviY9606 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rigid:f4XgV7vDvnrWgXKjWUmLFW9rCns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01892 uniprotkb:Q15306 intact:EBI-2800992|uniprotkb:Q15359|uniprotkb:A8K9C9|uniprotkb:B4DUG6|ensembl:ENSP00000471921 intact:EBI-751345|uniprotkb:Q5VUI7|uniprotkb:Q99660|intact:EBI-28969842|ensembl:ENSP00000370343 psi-mi:spib_human(display_long)|uniprotkb:SPIB(gene name)|psi-mi:SPIB(display_short) psi-mi:irf4_human(display_long)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:Multiple myeloma oncogene 1(gene name synonym)|uniprotkb:IRF4(gene name)|psi-mi:IRF4(display_short)|uniprotkb:MUM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680799|imex:IM-28774-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000270632|ensembl:ENST00000270632|ensembl:ENSP00000391877|ensembl:ENSP00000471921|ensembl:ENST00000439922|refseq:NP_003112.2|refseq:NP_001230928.1|refseq:NP_001230929.1|refseq:NP_001230927.1|ensembl:ENSG00000269404(gene)|ensembl:ENST00000595883(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036390|interpro:IPR036388|entrezgene/locuslink:6689(identity) refseq:NP_001182215.1|refseq:NP_002451.2|ensembl:ENSP00000370343|ensembl:ENSG00000137265(gene)|ensembl:ENST00000380956(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DLL|rcsb pdb:6TD4|rcsb pdb:7JM4|rcsb pdb:7O56|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-909733|interpro:IPR001346(Interferon regulatory factor)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|entrezgene/locuslink:3662(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EiWsB4rAy9HjTBy2oDde3sqeviY9606 rogid:32kCHCtSe1riCkTgTnnr5gMipfs9606 rigid:f4XgV7vDvnrWgXKjWUmLFW9rCns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23497 uniprotkb:P10242 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680791|imex:IM-28774-3027 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE|entrezgene/locuslink:6672(identity) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N|entrezgene/locuslink:4602(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rigid:CEq1k6R0L0frgO8TrH0+z8MSvMQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08047 uniprotkb:P08047 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680775|imex:IM-28774-1275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|entrezgene/locuslink:6667(identity) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|entrezgene/locuslink:6667(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 rigid:U24bngjmftrJfGtZqGB0uFW56M8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08047 uniprotkb:O43248 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680767|imex:IM-28774-1699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|entrezgene/locuslink:6667(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:QpTIK+LABXb6OOQe+7797GInFV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60248 uniprotkb:P17482 intact:EBI-5452954|uniprotkb:D3DTQ0|uniprotkb:P35717|uniprotkb:Q9Y6W7|uniprotkb:B4DWU7|ensembl:ENSP00000439311|ensembl:ENSP00000355354 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:sox15_human(display_long)|uniprotkb:SOX15(gene name)|psi-mi:SOX15(display_short)|uniprotkb:SOX12(gene name synonym)|uniprotkb:SOX20(gene name synonym)|uniprotkb:SOX26(gene name synonym)|uniprotkb:SOX27(gene name synonym)|uniprotkb:Protein SOX-12(gene name synonym)|uniprotkb:Protein SOX-20(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680759|imex:IM-28774-1273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008873.1|ensembl:ENSP00000355354|ensembl:ENSP00000439311|ensembl:ENST00000570788|ensembl:ENSP00000458286|ensembl:ENSG00000129194(gene)|ensembl:ENST00000250055(transcript)|ensembl:ENST00000538513(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008584"(male gonad development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014718"(positive regulation of satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030154"(cell differentiation)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048627"(myoblast development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031269|interpro:IPR036910|entrezgene/locuslink:6665(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:uZ6DNBbVJt+YhV4Bun7H+dI/Ac49606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:PxslcmWWaLiwfMM9iP/OKgwIQl4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R5C8 uniprotkb:Q04207 intact:EBI-647813|uniprotkb:Q8C155|uniprotkb:G5E8Q2|ensembl:ENSMUSP00000106264|ensembl:ENSMUSP00000106266 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:zmy11_mouse(display_long)|uniprotkb:Zmynd11(gene name)|psi-mi:Zmynd11(display_short) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680751|imex:IM-28774-3437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006516569.1|refseq:NP_001186070.1|refseq:NP_001334403.1|refseq:NP_001334405.1|dip:DIP-49596N|ensembl:ENSMUSG00000021156(gene)|ensembl:ENSMUST00000110634(transcript)|ensembl:ENSMUST00000110636(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q8R5C8|rcsb pdb:4N4G|rcsb pdb:4N4H|rcsb pdb:4N4I|entrezgene/locuslink:66505(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xxSgkZdMc1DQrhsIcIT6vnKBaFQ10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:Agcp+SEBC/q0vNlSAVpbHDVeN2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q80UW8 uniprotkb:Q60953 intact:EBI-6094615|ensembl:ENSMUSP00000004786 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:rpab1_mouse(display_long)|uniprotkb:Polr2e(gene name)|psi-mi:Polr2e(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680743|imex:IM-28774-3023 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079830.2|ensembl:ENSMUSG00000004667(gene)|ensembl:ENSMUST00000004786(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:66420(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NKA6+5grFwQn41K1TqXFHmmyXcs10090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:v8ORggoLOEohUbjyFioG+luXbFU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R2X8 uniprotkb:Q60862 intact:EBI-2364712|uniprotkb:Q3TJC4|uniprotkb:Q8C0U6|uniprotkb:Q9DAV7|ensembl:ENSMUSP00000083196|ensembl:ENSMUSP00000113479 intact:EBI-457142|ensembl:ENSMUSP00000027198 psi-mi:go45_mouse(display_long)|uniprotkb:Blzf1(gene name)|psi-mi:Blzf1(display_short)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym) psi-mi:orc2_mouse(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:Orc2l(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680735|imex:IM-28774-3435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153680.1|refseq:NP_001153681.1|refseq:NP_079781.2|ensembl:ENSMUSG00000026577(gene)|ensembl:ENSMUST00000086032(transcript)|ensembl:ENSMUST00000120447(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q8R2X8|rcsb pdb:5H3J|reactome:R-MMU-162658|entrezgene/locuslink:66352(identity) refseq:NP_032791.1|ensembl:ENSMUSG00000026037(gene)|ensembl:ENSMUST00000027198(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000808"(origin recognition complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005813"(centrosome)|go:"GO:0006260"(DNA replication)|interpro:IPR007220(Origin recognition complex subunit 2)|reactome:R-MMU-176187|reactome:R-MMU-68616|reactome:R-MMU-68689|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|refseq:NP_001258455.1|entrezgene/locuslink:18393(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:uKlwREE2gcEIp+l1JRlfHGzZY0c10090 rogid:mG5foO+hpAPT/3BIw9jDTSVR5p010090 rigid:FLuE7AdiY91tPzJE2PpPAI9bPx4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16533 uniprotkb:P31260 intact:EBI-11915024|ensembl:ENSP00000216294 intact:EBI-2293516|uniprotkb:O43370|uniprotkb:O43605|uniprotkb:Q15949|uniprotkb:Q504T1|ensembl:ENSP00000283921 psi-mi:snpc1_human(display_long)|uniprotkb:SNAPC1(gene name)|psi-mi:SNAPC1(display_short)|uniprotkb:Proximal sequence element-binding transcription factor subunit gamma(gene name synonym)|uniprotkb:SNAP43(gene name synonym)|uniprotkb:Small nuclear RNA-activating complex polypeptide 1(gene name synonym)|uniprotkb:snRNA-activating protein complex 43 kDa subunit(gene name synonym) psi-mi:hxa10_human(display_long)|uniprotkb:HOXA10(gene name)|psi-mi:HOXA10(display_short)|uniprotkb:HOX1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym)|uniprotkb:PL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680727|imex:IM-28774-2171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000023608(gene)|ensembl:ENST00000216294(transcript)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR019188|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|refseq:NP_003073.1|dip:DIP-504N|entrezgene/locuslink:6617(identity) refseq:NP_061824.3|ensembl:ENSG00000253293(gene)|ensembl:ENST00000283921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:3206(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xXCySYpmgoo2VmzFtT1iRFFUkj49606 rogid:MLQBPBS4U2GIsWQyBQ/oZlwQLkY9606 rigid:K/Bn09QLzJBL0bac8Phb+fneFRY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95863 uniprotkb:P09016 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680719|imex:IM-28774-2595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N|entrezgene/locuslink:6615(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:evixttwm5EqtqETozp4r2h8QNJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GM5 uniprotkb:P61457 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680695|imex:IM-28774-791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N|entrezgene/locuslink:6602(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:9VMAmqTd0OxssW48M8YJpsWUw9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04211 uniprotkb:Q9D8X5 intact:EBI-7847081|ensembl:ENSMUSP00000020692|intact:MINT-1517995 intact:EBI-16204625|ensembl:ENSMUSP00000020822|ensembl:ENSMUSP00000104471|uniprotkb:Q3U532 psi-mi:btg2_mouse(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Tis21(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible protein TIS21(gene name synonym) psi-mi:cnot8_mouse(display_long)|uniprotkb:Cnot8(gene name)|psi-mi:Cnot8(display_short)|uniprotkb:CCR4-associated factor 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681459|imex:IM-28774-1711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020423(gene)|ensembl:ENSMUST00000020692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|mint:Q04211|rcsb pdb:3DJN|go:"GO:0017148"(negative regulation of translation)|reactome:R-MMU-6804115|refseq:NP_031596.1|dip:DIP-41601N|entrezgene/locuslink:12227(identity) ensembl:ENSMUSG00000020515(gene)|ensembl:ENSMUST00000020822(transcript)|ensembl:ENSMUST00000108843(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|reactome:R-MMU-429947|reactome:R-MMU-6804115|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|refseq:NP_081225.1|refseq:XP_006534165.1|refseq:XP_006534166.1|refseq:XP_006534167.1|refseq:XP_006534168.1|refseq:XP_006534169.1|dip:DIP-61988N|entrezgene/locuslink:69125(identity) - comment:mint|function:Anti-proliferative protein. Modulates transcription regulation mediated by ESR1 - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7BocM19zCEv3H2oW41XX6DMgaTY10090 rogid:g5iKAkqD6ea+Pn/e/tXlXeIJ97U10090 rigid:AJEC+qFtsKAG989h7nzMPGw7oqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:O55203 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680874|imex:IM-28774-1277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:G4Vum2CWUpo3b9MYB7P5QHmbPug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D8X5 uniprotkb:P62325 intact:EBI-16204625|ensembl:ENSMUSP00000020822|ensembl:ENSMUSP00000104471|uniprotkb:Q3U532 intact:EBI-26671626|ensembl:ENSMUSP00000038863|uniprotkb:P31607 psi-mi:cnot8_mouse(display_long)|uniprotkb:Cnot8(gene name)|psi-mi:Cnot8(display_short)|uniprotkb:CCR4-associated factor 8(gene name synonym) psi-mi:btg1_mouse(display_long)|uniprotkb:B-cell translocation gene 1 protein(gene name synonym)|uniprotkb:Btg1(gene name)|psi-mi:Btg1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681443|imex:IM-28774-1707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020515(gene)|ensembl:ENSMUST00000020822(transcript)|ensembl:ENSMUST00000108843(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|reactome:R-MMU-429947|reactome:R-MMU-6804115|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|refseq:NP_081225.1|refseq:XP_006534165.1|refseq:XP_006534166.1|refseq:XP_006534167.1|refseq:XP_006534168.1|refseq:XP_006534169.1|dip:DIP-61988N|entrezgene/locuslink:69125(identity) ensembl:ENSMUSG00000036478(gene)|ensembl:ENSMUST00000038377(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033330|interpro:IPR033332|interpro:IPR036054|refseq:NP_031595.1|entrezgene/locuslink:12226(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:g5iKAkqD6ea+Pn/e/tXlXeIJ97U10090 rogid:+XRny4AEbQHi+qxKV1Qsf9bOFG010090 rigid:hk+BGaYhQUhRZSOANrUWfjggA4I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13207 uniprotkb:Q15744 intact:EBI-2853051|uniprotkb:Q16424|uniprotkb:Q7Z647|ensembl:ENSP00000240328 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:tbx2_human(display_long)|uniprotkb:TBX2(gene name)|psi-mi:TBX2(display_short) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681435|imex:IM-28774-2613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005985.3|ensembl:ENSG00000121068(gene)|ensembl:ENST00000240328(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007569"(cell aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060465"(pharynx development)|go:"GO:0060560"(developmental growth involved in morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0060596"(mammary placode formation)|go:"GO:0072105"(ureteric peristalsis)|go:"GO:0090398"(cellular senescence)|go:"GO:1901208"(negative regulation of heart looping)|go:"GO:1901211"(negative regulation of cardiac chamber formation)|go:"GO:1905222"(atrioventricular canal morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR022582|interpro:IPR036960|go:"GO:1905072"(cardiac jelly development)|entrezgene/locuslink:6909(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:r5HgwtlqAyKL7wBI2lrjj/uhqMo9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:j0U/z0CLRtvD6t3faWT8PpHuOQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15633 uniprotkb:Q15633 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681419|imex:IM-28774-3033 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:oNtQ23qX36sbSjgYaaiIixHSEhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15633 uniprotkb:Q92886 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 intact:EBI-10279647|uniprotkb:Q96HE1|uniprotkb:Q5U0Q9|ensembl:ENSP00000317580 psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:ngn1_human(display_long)|uniprotkb:NEUROG1(gene name)|psi-mi:NEUROG1(display_short)|uniprotkb:BHLHA6(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 6(gene name synonym)|uniprotkb:NEUROD3(gene name synonym)|uniprotkb:NGN(gene name synonym)|uniprotkb:NGN1(gene name synonym)|uniprotkb:Neurogenic basic-helix-loop-helix protein(gene name synonym)|uniprotkb:Neurogenic differentiation factor 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681411|imex:IM-28774-2179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) refseq:NP_006152.2|ensembl:ENSG00000181965(gene)|ensembl:ENST00000314744(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0007399"(nervous system development)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032653|interpro:IPR036638|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:4762(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rogid:kz1JEusy5ubX6GwV80OmH4UQFEQ9606 rigid:yXmbbFyuEK8QXxjUEDc1hB0+du4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16559 uniprotkb:Q06455 intact:EBI-10237959|uniprotkb:A0AVI7|ensembl:ENSP00000334547 intact:EBI-743342|uniprotkb:O14784|uniprotkb:Q06456|uniprotkb:Q14873|uniprotkb:Q16239|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q6IBL1|uniprotkb:Q92479|uniprotkb:Q9BRZ0|ensembl:ENSP00000265814|ensembl:ENSP00000428543|ensembl:ENSP00000481112|ensembl:ENSP00000481315|ensembl:ENSP00000481799|uniprotkb:B7Z4P4|uniprotkb:E7EPN4|uniprotkb:Q6NXH1|uniprotkb:Q7Z4J5 psi-mi:tal2_human(display_long)|uniprotkb:TAL2(gene name)|psi-mi:TAL2(display_short)|uniprotkb:BHLHA19(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 19(gene name synonym) psi-mi:mtg8_human(display_long)|uniprotkb:Protein MTG8(gene name synonym)|uniprotkb:Protein ETO(gene name synonym)|uniprotkb:Eight twenty one protein(gene name synonym)|uniprotkb:Cyclin-D-related protein(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 2(gene name synonym)|uniprotkb:RUNX1T1(gene name)|psi-mi:RUNX1T1(display_short)|uniprotkb:AML1T1(gene name synonym)|uniprotkb:CBFA2T1(gene name synonym)|uniprotkb:CDR(gene name synonym)|uniprotkb:ETO(gene name synonym)|uniprotkb:MTG8(gene name synonym)|uniprotkb:ZMYND2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681403|imex:IM-28774-1297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005412.1|ensembl:ENSG00000186051(gene)|ensembl:ENST00000334077(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|entrezgene/locuslink:6887(identity) refseq:NP_001185554.1|refseq:NP_001185555.1|refseq:NP_001185556.1|refseq:NP_001185557.1|refseq:NP_001185558.1|refseq:NP_001185559.1|refseq:NP_001185560.1|refseq:NP_001185561.1|refseq:NP_004340.1|refseq:NP_783552.1|refseq:NP_783553.1|refseq:NP_783554.1|ensembl:ENSG00000079102(gene)|ensembl:ENST00000265814(transcript)|ensembl:ENST00000523629(transcript)|ensembl:ENST00000613302(transcript)|ensembl:ENST00000614812(transcript)|ensembl:ENST00000617740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|refseq:XP_011515653.1|refseq:XP_011515654.1|refseq:XP_011515655.1|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:Q06455|rcsb pdb:1WQ6|rcsb pdb:2DJ8|rcsb pdb:2H7B|rcsb pdb:2KNH|rcsb pdb:2KYG|rcsb pdb:2OD1|rcsb pdb:2ODD|rcsb pdb:2PP4|rcsb pdb:4JOL|refseq:NP_001185563.1|refseq:NP_001185562.1|refseq:NP_001185608.1|refseq:XP_006716739.1|refseq:XP_016869420.1|refseq:XP_016869421.1|refseq:XP_016869422.1|refseq:XP_016869423.1|refseq:XP_016869424.1|refseq:XP_016869425.1|refseq:XP_016869426.1|dip:DIP-29401N|entrezgene/locuslink:862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JgO8ZFHP9X70qLk3jzH1SbU+xiU9606 rogid:SMomKOZSbtqhKiAkkUkabKbC8/09606 rigid:mSYw7yip/9+Iqd2CD1EEr5N77kU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16559 uniprotkb:P25791 intact:EBI-10237959|uniprotkb:A0AVI7|ensembl:ENSP00000334547 intact:EBI-739696|uniprotkb:Q9HD58|ensembl:ENSP00000379175 psi-mi:tal2_human(display_long)|uniprotkb:TAL2(gene name)|psi-mi:TAL2(display_short)|uniprotkb:BHLHA19(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 19(gene name synonym) psi-mi:rbtn2_human(display_long)|uniprotkb:LMO2(gene name)|psi-mi:LMO2(display_short)|uniprotkb:RBTN2(gene name synonym)|uniprotkb:RHOM2(gene name synonym)|uniprotkb:TTG2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym)|uniprotkb:RBTNL1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681395|imex:IM-28774-1705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005412.1|ensembl:ENSG00000186051(gene)|ensembl:ENST00000334077(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|entrezgene/locuslink:6887(identity) refseq:NP_001135787.1|refseq:NP_001135788.1|refseq:NP_005565.2|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:4KFZ|reactome:R-HSA-8939236|ensembl:ENSG00000135363(gene)|ensembl:ENST00000395833(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|refseq:XP_005252978.1|refseq:XP_016873216.1|refseq:XP_016873217.1|refseq:XP_016873218.1|refseq:XP_016873219.1|refseq:XP_016873220.1|refseq:XP_016873221.1|refseq:XP_016873222.1|entrezgene/locuslink:4005(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:JgO8ZFHP9X70qLk3jzH1SbU+xiU9606 rogid:o3vD6A43ue8k3BhmFh/mgyYvhsw9606 rigid:P96XLzIbtIBPYRKigu+NRB2OoWY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15545 uniprotkb:P15976 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681387|imex:IM-28774-3459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:6879(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:/oJ7KxhtAO0SzvHs4i85ZpC8oA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PE2 uniprotkb:Q61545 intact:EBI-26681354|ensembl:ENSMUSP00000022164 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:anra2_mouse(display_long)|uniprotkb:RFXANK-like protein 2(gene name synonym)|uniprotkb:Ankra2(gene name)|psi-mi:Ankra2(display_short)|uniprotkb:Ankra(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681379|imex:IM-28774-1703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021661(gene)|ensembl:ENSMUST00000022164(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1990393"(3M complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_075961.1|entrezgene/locuslink:68558(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:P9tJCRYEUkXcphySGig/su7NzjY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:hNPSaEIQjDWnR5QwakpDgfGRT+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00267 uniprotkb:P61457 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681346|imex:IM-28774-3457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:oNO+SVaqQ1gi29VT1Ci6g02RHEY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00267 uniprotkb:P32780 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681338|imex:IM-28774-3031 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N|entrezgene/locuslink:2965(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:l+zgtas9MPOHPDfFr62PZN5Ss3E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63272 uniprotkb:Q01844 intact:EBI-727250|uniprotkb:Q16550|uniprotkb:Q62387|uniprotkb:Q6ZP89|uniprotkb:B2R4X8|uniprotkb:D3DTZ4|ensembl:ENSP00000225504|ensembl:ENSP00000462670 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:spt4h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 14 kDa subunit(gene name synonym)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:SPT4H(gene name synonym)|uniprotkb:SUPT4H(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681330|imex:IM-28774-2177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003159.1|ensembl:ENSG00000213246(gene)|ensembl:ENST00000225504(transcript)|ensembl:ENST00000580947(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|mint:P63272|rcsb pdb:3H7H|rcsb pdb:5OIK|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|dip:DIP-40644N|entrezgene/locuslink:6827(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:s/sTjdU4ssKTbUI/q/l9JsmkxZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CQZ1 uniprotkb:O55144 intact:EBI-26681299|ensembl:ENSMUSP00000034300|ensembl:ENSMUSP00000148390|uniprotkb:Q3UKN1 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:hsbp1_mouse(display_long)|uniprotkb:Hsbp1(gene name)|psi-mi:Hsbp1(display_short) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681322|imex:IM-28774-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031839(gene)|ensembl:ENSMUST00000034300(transcript)|ensembl:ENSMUST00000212468(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR009643(Heat shock factor binding 1)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|refseq:NP_077181.1|entrezgene/locuslink:68196(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3gfNSmRtug6jxHUB+UV7iKWf0sw10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:lYFYML0ErN+wKKQzsyBNm8/RWC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D902 uniprotkb:O55144 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681291|imex:IM-28774-3029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:/1ZfxI5Qpo1kqWKIITqN9+bB5p4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D902 uniprotkb:Q9DCP9 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 intact:EBI-26681261|ensembl:ENSMUSP00000000356|uniprotkb:O88675|uniprotkb:Q3UVI4 psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:dazp2_mouse(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:Proline-rich protein expressed in brain(gene name synonym)|uniprotkb:Dazap2(gene name)|psi-mi:Dazap2(display_short)|uniprotkb:Prtb(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681283|imex:IM-28774-3455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) ensembl:ENSMUSG00000000346(gene)|ensembl:ENSMUST00000000356(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR022730|refseq:NP_036003.2|entrezgene/locuslink:23994(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rogid:MUKun3YQDzpPb4Bkt/xIChXIMsA10090 rigid:ZEd8+YXid/xG1oaJ+x0aeg2HZlg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D902 uniprotkb:Q60749 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 intact:EBI-519077|uniprotkb:A2ACH3|uniprotkb:Q7M4N5|uniprotkb:Q3U8T3|uniprotkb:Q60735|uniprotkb:Q99M33|ensembl:ENSMUSP00000066516|ensembl:ENSMUSP00000115402|uniprotkb:B2KG38 psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:khdr1_mouse(display_long)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:Khdrbs1(gene name)|psi-mi:Khdrbs1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681253|imex:IM-28774-1295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) ensembl:ENSMUSG00000028790(gene)|ensembl:ENSMUST00000066257(transcript)|ensembl:ENSMUST00000129342(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q60749|reactome:R-MMU-8849468|refseq:NP_035447.3|dip:DIP-2861N|entrezgene/locuslink:20218(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rogid:FtKudvPZeoFATHi0fUbnPsJgons10090 rigid:Lld+tflG80QdNSWgc+vH1vASguI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D902 uniprotkb:Q60953 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681245|imex:IM-28774-2175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:oOyXMQbrNE7vkAIdKTjngm0wb9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D902 uniprotkb:Q07279 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681237|imex:IM-28774-801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:EEf03IpXOLXJ7OXfGp/vmEgbhfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41778 uniprotkb:Q9DB42 intact:EBI-6996259|ensembl:ENSMUSP00000135516|intact:MINT-96519 intact:EBI-26681199|ensembl:ENSMUSP00000030644|uniprotkb:Q3UZX2|uniprotkb:Q99J54 psi-mi:pbx1_mouse(display_long)|uniprotkb:Pbx1(gene name)|psi-mi:Pbx1(display_short)|uniprotkb:Pbx-1(gene name synonym)|uniprotkb:Homeobox protein PBX1(gene name synonym) psi-mi:zn593_mouse(display_long)|uniprotkb:Zinc finger protein T86(gene name synonym)|uniprotkb:Znf593(gene name)|psi-mi:Znf593(display_short)|uniprotkb:Zfp593(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681229|imex:IM-28774-2173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278437.1|ensembl:ENSMUSG00000052534(gene)|ensembl:ENSMUST00000176540(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007548"(sex differentiation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P41778|rcsb pdb:1DU6|rcsb pdb:1LFU|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_032809.1|refseq:NP_899198.1|dip:DIP-6107N|entrezgene/locuslink:18514(identity) ensembl:ENSMUSG00000028840(gene)|ensembl:ENSMUST00000030644(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|refseq:NP_077177.2|entrezgene/locuslink:68040(identity) - comment:mint|function:"Plays a role in the cAMP-dependent regulation of CYP17 gene expression via its cAMP-regulatory sequence (CRS1) 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. May have a role in steroidogenesis and, subsequently, sexual development and differentiation" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YViNj+q9A6e+VCAkMUQowMzvowE10090 rogid:DUb6YNU3ZXvRcP4U9d0AALNMdWY10090 rigid:LMt9koJfUZBo1sO96Kd002/d93Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9DB42 uniprotkb:P70662 intact:EBI-26681199|ensembl:ENSMUSP00000030644|uniprotkb:Q3UZX2|uniprotkb:Q99J54 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:zn593_mouse(display_long)|uniprotkb:Zinc finger protein T86(gene name synonym)|uniprotkb:Znf593(gene name)|psi-mi:Znf593(display_short)|uniprotkb:Zfp593(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681221|imex:IM-28774-1293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000028840(gene)|ensembl:ENSMUST00000030644(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|refseq:NP_077177.2|entrezgene/locuslink:68040(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:DUb6YNU3ZXvRcP4U9d0AALNMdWY10090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:Iju4eutDixwOQJ+aMnk7jTC6u3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42226 uniprotkb:P40763 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681191|imex:IM-28774-1291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|entrezgene/locuslink:6774(identity) - - crc64:6C00632211C8012D figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:Q0nAESFUSeCXpgQK4/cOcsdlcN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40763 uniprotkb:O43248 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 intact:EBI-2652631|uniprotkb:A8K7D1|uniprotkb:Q96DH2|ensembl:ENSP00000446680 psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:hxc11_human(display_long)|uniprotkb:HOXC11(gene name)|psi-mi:HOXC11(display_short)|uniprotkb:HOX3H(gene name synonym)|uniprotkb:Homeobox protein Hox-3H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681183|imex:IM-28774-3453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|entrezgene/locuslink:6774(identity) refseq:NP_055027.1|ensembl:ENSG00000123388(gene)|ensembl:ENST00000546378(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:3227(identity) - crc64:6C00632211C8012D - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rogid:G3nt4+imve6xwS8vB4oTwzFv4MA9606 rigid:QcAXqcsgYixm3E4nrtuiap12DGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62869 uniprotkb:P31310 intact:EBI-2659323|uniprotkb:Q80W20|uniprotkb:Q63529|ensembl:ENSMUSP00000066210 intact:EBI-446033|uniprotkb:Q80Y22|ensembl:ENSMUSP00000120276 psi-mi:elob_mouse(display_long)|uniprotkb:Elob(gene name)|psi-mi:Elob(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:Tceb2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:hxa10_mouse(display_long)|uniprotkb:Hoxa10(gene name)|psi-mi:Hoxa10(display_short)|uniprotkb:Hox-1.8(gene name synonym)|uniprotkb:Hoxa-10(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681175|imex:IM-28774-799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080581.1|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|go:"GO:0030891"(VCB complex)|interpro:IPR039049|mint:P62869|rcsb pdb:2FNJ|rcsb pdb:4JGH|reactome:R-MMU-112382|reactome:R-MMU-1234176|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-75955|reactome:R-MMU-8951664|reactome:R-MMU-9705462|reactome:R-MMU-983168|ensembl:ENSMUSG00000055839(gene)|ensembl:ENSMUST00000069579(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|entrezgene/locuslink:67673(identity) refseq:NP_001116422.1|refseq:NP_032289.2|ensembl:ENSMUSG00000000938(gene)|ensembl:ENSMUST00000125581(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0010468"(regulation of gene expression)|entrezgene/locuslink:15395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7W4I9AcvS1GK89dMmBOImMYNgLY10090 rogid:vWwVapO3YyVd8TG6MbGvBHZHOMo10090 rigid:+hC9QUEyPQIVAlik9FZHMjlhaJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60224 uniprotkb:P55771 intact:EBI-745513|uniprotkb:Q5JQZ0|uniprotkb:Q9UJU9|uniprotkb:B2RPE3|ensembl:ENSP00000469011|ensembl:ENSP00000469394|uniprotkb:A8MYD4|uniprotkb:Q3SYD4 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:ssx4_human(display_long)|uniprotkb:Cancer/testis antigen 5.4(gene name synonym)|uniprotkb:SSX4(gene name)|psi-mi:SSX4(display_short)|uniprotkb:SSX4B(gene name)|psi-mi:SSX4B(display_short)|uniprotkb:SSX4A(gene name synonym) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681167|imex:IM-28774-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030004.1|refseq:NP_005627.1|refseq:NP_783856.1|ensembl:ENSG00000268009(gene)|ensembl:ENSG00000269791(gene)|ensembl:ENST00000595235(transcript)|ensembl:ENST00000595689(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|refseq:NP_001035702.1|refseq:XP_016885102.1|refseq:XP_016885248.1|entrezgene/locuslink:6759(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XHHJJoIvvSIjm/AO1gB1lYvXlHE9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:2aCW2etaft3mYUIz3LjGXCOj+qY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60225 uniprotkb:Q16621 intact:EBI-10186198|uniprotkb:Q5JQ59|uniprotkb:Q96AW3|uniprotkb:Q5JQ60|ensembl:ENSP00000290558 intact:EBI-726369|uniprotkb:Q07720|uniprotkb:Q6ICV9|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558 psi-mi:ssx5_human(display_long)|uniprotkb:SSX5(gene name)|psi-mi:SSX5(display_short) psi-mi:nfe2_human(display_long)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:NFE2(gene name)|psi-mi:NFE2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681159|imex:IM-28774-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066295.3|refseq:NP_783729.1|refseq:XP_016885247.1|refseq:XP_011542251.1|ensembl:ENSG00000165583(gene)|ensembl:ENST00000347757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:6758(identity) refseq:NP_001248390.1|refseq:NP_001129495.1|refseq:NP_006154.1|ensembl:ENSP00000312436|ensembl:ENSP00000397185|ensembl:ENSP00000439120|ensembl:ENSP00000447558|refseq:XP_005268963.1|ensembl:ENSG00000123405(gene)|ensembl:ENST00000312156(transcript)|ensembl:ENST00000435572(transcript)|ensembl:ENST00000540264(transcript)|ensembl:ENST00000553070(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007599"(hemostasis)|go:"GO:0016605"(PML body)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|rcsb pdb:1LVX|rcsb pdb:2KZ5|reactome:R-HSA-8936459|reactome:R-HSA-983231|dip:DIP-57844N|entrezgene/locuslink:4778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:sVINA7fZyttxJg58NXmqzVL9PAc9606 rogid:Y8uGUXDj1DbJnvZT2aZ5suX/yDE9606 rigid:S7lsB0WRpfhm2HGBQmfhCQz2838 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9DCD2 uniprotkb:Q61545 intact:EBI-8458194|uniprotkb:Q9CVD8|intact:MINT-4140395|uniprotkb:Q8VDT5|ensembl:ENSMUSP00000019614 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:syf1_mouse(display_long)|uniprotkb:Xab2(gene name)|psi-mi:Xab2(display_short)|uniprotkb:Syf1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681151|imex:IM-28774-2609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080432.1|ensembl:ENSMUSG00000019470(gene)|ensembl:ENSMUST00000019614(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9DCD2|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-72163|entrezgene/locuslink:67439(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - comment:mint|function:"Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WJm4k7rkK9zKpEkQeqVlQhe3iB810090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:HBA/mxFmNrO7MG81hS9d5F9d3EQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXU1 uniprotkb:P63157 intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157 intact:EBI-26681110|ensembl:ENSMUSP00000053147|ensembl:ENSMUSP00000109478|ensembl:ENSMUSP00000109480|uniprotkb:Q9JK26 psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:barh1_mouse(display_long)|uniprotkb:Bar-class homeodomain protein MBH2(gene name synonym)|uniprotkb:BarH-related homeobox protein 1(gene name synonym)|uniprotkb:Barhl1(gene name)|psi-mi:Barhl1(display_short)|uniprotkb:Bhx1(gene name synonym)|uniprotkb:Mbh2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681143|imex:IM-28774-3451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436|entrezgene/locuslink:67279(identity) ensembl:ENSMUSG00000026805(gene)|ensembl:ENSMUST00000050776(transcript)|ensembl:ENSMUST00000113847(transcript)|ensembl:ENSMUST00000113849(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030901"(midbrain development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR001356(Homeobox)|refseq:NP_001157658.1|refseq:NP_062319.1|refseq:XP_006498245.1|refseq:XP_006498246.1|refseq:XP_011237440.1|entrezgene/locuslink:54422(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090 rogid:KNqv1fU+PSWeMxt9yR3hNanXBns10090 rigid:QlrEleqcbQUZkUOSeEh96BbsXfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXU1 uniprotkb:O55144 intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681102|imex:IM-28774-3449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436|entrezgene/locuslink:67279(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:RdptOVxjgZIiUY+qKBF+4W3qYOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D6J1 uniprotkb:Q9JKN5 intact:EBI-26681065|ensembl:ENSMUSP00000008350|uniprotkb:Q8BZA6|uniprotkb:Q8C151|uniprotkb:Q9CX09 intact:EBI-1213712|ensembl:ENSMUSP00000061408 psi-mi:cers4_mouse(display_long)|uniprotkb:LAG1 longevity assurance homolog 4(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS4(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 1(gene name synonym)|uniprotkb:Cers4(gene name)|psi-mi:Cers4(display_short)|uniprotkb:Lass4(gene name synonym)|uniprotkb:Trh1(gene name synonym) psi-mi:olig1_mouse(display_long)|uniprotkb:Olig1(gene name)|psi-mi:Olig1(display_short)|uniprotkb:Oligodendrocyte-specific bHLH transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681094|imex:IM-28774-1289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000008206(gene)|ensembl:ENSMUST00000008350(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-MMU-1660661|interpro:IPR001356(Homeobox)|refseq:NP_080334.3|refseq:XP_006508924.1|refseq:XP_006508925.1|refseq:XP_006508926.1|entrezgene/locuslink:67260(identity) refseq:NP_058664.2|ensembl:ENSMUSG00000046160(gene)|ensembl:ENSMUST00000056882(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q9JKN5|entrezgene/locuslink:50914(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WXdg4AUzrAxTv5NpIJXmy+Nu2Ow10090 rogid:1R93ekMg/uZq5unF9PJGlf/iiJ810090 rigid:rXm8tc6Uxp/cUL2IuAKxAOpRS/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CPV7 uniprotkb:Q9JL60 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 intact:EBI-26679699|ensembl:ENSMUSP00000030733|ensembl:ENSMUSP00000101584|ensembl:ENSMUSP00000101585|ensembl:ENSMUSP00000131331|uniprotkb:Q80Y88 psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:gmeb1_mouse(display_long)|uniprotkb:Gmeb1(gene name)|psi-mi:Gmeb1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681057|imex:IM-28774-1701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) ensembl:ENSMUSG00000028901(gene)|ensembl:ENSMUST00000030733(transcript)|ensembl:ENSMUST00000105964(transcript)|ensembl:ENSMUST00000105965(transcript)|ensembl:ENSMUST00000168553(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051008"(Hsp27 protein binding)|interpro:IPR000770(SAND)|interpro:IPR010919(SAND-like)|interpro:IPR024830|refseq:NP_001116464.1|refseq:NP_064669.2|refseq:XP_006539141.1|refseq:XP_006539142.1|refseq:XP_006539143.1|refseq:XP_017175821.1|entrezgene/locuslink:56809(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rogid:YIdkBFnwCIT+NYGvVCNFEwlr2e410090 rigid:obNNcFeTze0GcfIsDEYqzFSzXSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CPV7 uniprotkb:Q9WUL8 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681049|imex:IM-28774-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:LBDH3tyiqVKxEdaao+Be0Ib8GHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CPV7 uniprotkb:P15806 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681041|imex:IM-28774-1287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:h1l9J9S3pSApJmOVb/QzqFMExxE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CPV7 uniprotkb:Q07279 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681033|imex:IM-28774-3447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:4p7/ow1jscFwN8CKKlan/5XJ/l0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CPV7 uniprotkb:P31245 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681025|imex:IM-28774-1285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:ub4mEzNlr3HzkzOUNZjKprxn1NI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CPV7 uniprotkb:Q61545 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681017|imex:IM-28774-3445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:1VXofufz8eYMRm4GTLhN8U6lH0Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q9CYZ8 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680962|imex:IM-28774-797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:eAWmEUHD1SVupteGZnGAfi42/94 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q60769 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-646595|uniprotkb:Q3U968|ensembl:ENSMUSP00000019997|ensembl:ENSMUSP00000101167 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:tnap3_mouse(display_long)|uniprotkb:Putative DNA-binding protein A20(gene name synonym)|uniprotkb:Zinc finger protein A20(gene name synonym)|uniprotkb:Tnfaip3(gene name)|psi-mi:Tnfaip3(display_short)|uniprotkb:Tnfip3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680954|imex:IM-28774-2607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) refseq:NP_033423.3|dip:DIP-41120N|refseq:XP_006512765.1|ensembl:ENSMUSG00000019850(gene)|ensembl:ENSMUST00000019997(transcript)|ensembl:ENSMUST00000105527(transcript)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002632"(negative regulation of granuloma formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019900"(kinase binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034148"(negative regulation of toll-like receptor 5 signaling pathway)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070429"(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0072573"(tolerance induction to lipopolysaccharide)|go:"GO:0072666"(establishment of protein localization to vacuole)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1990168"(protein K33-linked deubiquitination)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR033478|mint:Q60769|rcsb pdb:5DQ6|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689896|reactome:R-MMU-936440|entrezgene/locuslink:21929(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:hFNjd3fxx9grjtEq3kAdU0fiFh010090 rigid:IuQ0YvzWIdmEayRPa98GkOZf/Vc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q61751 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-26673380|ensembl:ENSMUSP00000020628|ensembl:ENSMUSP00000099827|uniprotkb:Q9QXU0 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:z354a_mouse(display_long)|uniprotkb:Kidney, ischemia, and developmentally-regulated protein 1(gene name synonym)|uniprotkb:Renal transcription factor Kid-1(gene name synonym)|uniprotkb:Transcription factor 17(gene name synonym)|uniprotkb:Znf354a(gene name)|psi-mi:Znf354a(display_short)|uniprotkb:Kid1(gene name synonym)|uniprotkb:Tcf17(gene name synonym)|uniprotkb:Zfp354a(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680946|imex:IM-28774-2605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000020364(gene)|ensembl:ENSMUST00000020628(transcript)|ensembl:ENSMUST00000102766(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007576"(nucleolar fragmentation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR041697|reactome:R-MMU-212436|refseq:NP_001313495.1|refseq:NP_033355.2|refseq:XP_006532853.1|entrezgene/locuslink:21408(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:bDgnQBZ5YOloFmDhpNOZdE25SXQ10090 rigid:q4R4JjSB4t1TYvEFxodCygOlJZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:O88609 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-13951208|uniprotkb:Q0VEN6 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680938|imex:IM-28774-795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rigid:W7fYkBg+aq0vmP/oe8qC9Tg4tdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:O88609 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-13951208|uniprotkb:Q0VEN6 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680930|imex:IM-28774-3443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rigid:W7fYkBg+aq0vmP/oe8qC9Tg4tdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:P61969 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-26669746|ensembl:ENSMUSP00000113513|ensembl:ENSMUSP00000113840|ensembl:ENSMUSP00000113865|uniprotkb:O00158|uniprotkb:O88894 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lmo4_mouse(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:Lmo4(gene name)|psi-mi:Lmo4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680922|imex:IM-28774-1283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000028266(gene)|ensembl:ENSMUST00000120539(transcript)|ensembl:ENSMUST00000121112(transcript)|ensembl:ENSMUST00000121796(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0050865"(regulation of cell activation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2DFY|rcsb pdb:2MBV|refseq:NP_001155241.1|refseq:NP_001155242.1|refseq:NP_034853.1|entrezgene/locuslink:16911(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE10090 rigid:YZVsDdzWF21MzdE08x8hvnc6/OQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q9WUH2 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680914|imex:IM-28774-3441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rigid:f3a3l+1IjYbi72fpkygqDWX3Yec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q9WUH2 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680906|imex:IM-28774-2603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rigid:f3a3l+1IjYbi72fpkygqDWX3Yec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q9Z0S2 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-26669558|ensembl:ENSMUSP00000000253 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680898|imex:IM-28774-2601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rigid:cIDeusgeuHs1rCaEZSlWFTUivTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:Q9Z0S2 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-26669558|ensembl:ENSMUSP00000000253 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680890|imex:IM-28774-1281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rigid:cIDeusgeuHs1rCaEZSlWFTUivTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CYZ8 uniprotkb:O55203 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26680882|imex:IM-28774-1279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:G4Vum2CWUpo3b9MYB7P5QHmbPug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D8X5 uniprotkb:P62325 intact:EBI-16204625|ensembl:ENSMUSP00000020822|ensembl:ENSMUSP00000104471|uniprotkb:Q3U532 intact:EBI-26671626|ensembl:ENSMUSP00000038863|uniprotkb:P31607 psi-mi:cnot8_mouse(display_long)|uniprotkb:Cnot8(gene name)|psi-mi:Cnot8(display_short)|uniprotkb:CCR4-associated factor 8(gene name synonym) psi-mi:btg1_mouse(display_long)|uniprotkb:B-cell translocation gene 1 protein(gene name synonym)|uniprotkb:Btg1(gene name)|psi-mi:Btg1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681451|imex:IM-28774-1709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020515(gene)|ensembl:ENSMUST00000020822(transcript)|ensembl:ENSMUST00000108843(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|reactome:R-MMU-429947|reactome:R-MMU-6804115|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|refseq:NP_081225.1|refseq:XP_006534165.1|refseq:XP_006534166.1|refseq:XP_006534167.1|refseq:XP_006534168.1|refseq:XP_006534169.1|dip:DIP-61988N|entrezgene/locuslink:69125(identity) ensembl:ENSMUSG00000036478(gene)|ensembl:ENSMUST00000038377(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033330|interpro:IPR033332|interpro:IPR036054|refseq:NP_031595.1|entrezgene/locuslink:12226(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:g5iKAkqD6ea+Pn/e/tXlXeIJ97U10090 rogid:+XRny4AEbQHi+qxKV1Qsf9bOFG010090 rigid:hk+BGaYhQUhRZSOANrUWfjggA4I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15370 uniprotkb:Q15369 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681499|imex:IM-28774-2183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N|entrezgene/locuslink:6923(identity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N|entrezgene/locuslink:6921(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:ChwdlwnjrWMP/3O5qvrcyJG5Ytw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D7M8 uniprotkb:Q07279 intact:EBI-8339168|intact:MINT-4133085|uniprotkb:Q78KE6|uniprotkb:Q6ZWW0|ensembl:ENSMUSP00000025106 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:rpb4_mouse(display_long)|uniprotkb:Polr2d(gene name)|psi-mi:Polr2d(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681507|imex:IM-28774-2615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081278.1|refseq:NP_081377.1|ensembl:ENSMUSG00000024258(gene)|ensembl:ENSMUST00000025106(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:Q9D7M8|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69241(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm8810090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:FRwaPfxlKhei/q3KqJojkuNxllE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15370 uniprotkb:Q15744 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681483|imex:IM-28774-2181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N|entrezgene/locuslink:6923(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:3BcfVULVbwDfJGohM4+2aV8iuNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D8X5 uniprotkb:O55144 intact:EBI-16204625|ensembl:ENSMUSP00000020822|ensembl:ENSMUSP00000104471|uniprotkb:Q3U532 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:cnot8_mouse(display_long)|uniprotkb:Cnot8(gene name)|psi-mi:Cnot8(display_short)|uniprotkb:CCR4-associated factor 8(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681475|imex:IM-28774-1715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020515(gene)|ensembl:ENSMUST00000020822(transcript)|ensembl:ENSMUST00000108843(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|reactome:R-MMU-429947|reactome:R-MMU-6804115|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|refseq:NP_081225.1|refseq:XP_006534165.1|refseq:XP_006534166.1|refseq:XP_006534167.1|refseq:XP_006534168.1|refseq:XP_006534169.1|dip:DIP-61988N|entrezgene/locuslink:69125(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:g5iKAkqD6ea+Pn/e/tXlXeIJ97U10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:/09iZxUv/2NJgpKpN1JIzHVi6PA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04211 uniprotkb:Q9D8X5 intact:EBI-7847081|ensembl:ENSMUSP00000020692|intact:MINT-1517995 intact:EBI-16204625|ensembl:ENSMUSP00000020822|ensembl:ENSMUSP00000104471|uniprotkb:Q3U532 psi-mi:btg2_mouse(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Tis21(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible protein TIS21(gene name synonym) psi-mi:cnot8_mouse(display_long)|uniprotkb:Cnot8(gene name)|psi-mi:Cnot8(display_short)|uniprotkb:CCR4-associated factor 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681467|imex:IM-28774-1713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020423(gene)|ensembl:ENSMUST00000020692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|mint:Q04211|rcsb pdb:3DJN|go:"GO:0017148"(negative regulation of translation)|reactome:R-MMU-6804115|refseq:NP_031596.1|dip:DIP-41601N|entrezgene/locuslink:12227(identity) ensembl:ENSMUSG00000020515(gene)|ensembl:ENSMUST00000020822(transcript)|ensembl:ENSMUST00000108843(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|reactome:R-MMU-429947|reactome:R-MMU-6804115|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|refseq:NP_081225.1|refseq:XP_006534165.1|refseq:XP_006534166.1|refseq:XP_006534167.1|refseq:XP_006534168.1|refseq:XP_006534169.1|dip:DIP-61988N|entrezgene/locuslink:69125(identity) - comment:mint|function:Anti-proliferative protein. Modulates transcription regulation mediated by ESR1 - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7BocM19zCEv3H2oW41XX6DMgaTY10090 rogid:g5iKAkqD6ea+Pn/e/tXlXeIJ97U10090 rigid:AJEC+qFtsKAG989h7nzMPGw7oqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14186 uniprotkb:Q14209 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-718476|uniprotkb:Q7Z6H1|uniprotkb:B2R9W1|ensembl:ENSP00000355249|ensembl:ENSP00000489612 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f2_human(display_long)|uniprotkb:E2F2(gene name)|psi-mi:E2F2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681675|imex:IM-28774-1305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|entrezgene/locuslink:7027(identity) refseq:NP_004082.1|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q14209|rcsb pdb:1N4M|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-69231|reactome:R-HSA-9661069|ensembl:ENSG00000007968(gene)|ensembl:ENSG00000282899(gene)|ensembl:ENST00000361729(transcript)|ensembl:ENST00000634683(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-258N|entrezgene/locuslink:1870(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:mTyyEcashAWBpjb0viYJv5OiREY9606 rigid:TXOXULIYXzxmx/W3fvFsbMkiw9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14186 uniprotkb:Q01094 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-448924|uniprotkb:Q13143|uniprotkb:Q92768|ensembl:ENSP00000345571 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f1_human(display_long)|uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)|uniprotkb:PBR3(gene name synonym)|uniprotkb:E2F1(gene name)|psi-mi:E2F1(display_short)|uniprotkb:RBBP3(gene name synonym)|uniprotkb:pRB-binding protein E2F-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681667|imex:IM-28774-1725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|entrezgene/locuslink:7027(identity) refseq:NP_005216.1|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048255"(mRNA stabilization)|ensembl:ENSG00000101412(gene)|ensembl:ENST00000343380(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804116|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q01094|rcsb pdb:1H24|rcsb pdb:1O9K|rcsb pdb:2AZE|rcsb pdb:5M9N|rcsb pdb:5M9O|rcsb pdb:6G0P|rcsb pdb:6ULS|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|dip:DIP-24227N|entrezgene/locuslink:1869(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:vPNenpmxyXpHjMzUID54cwMFk+Y9606 rigid:IUXL+zpGZ3zjL29C+3orkMH0lUc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P28357 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-26671369|ensembl:ENSMUSP00000058490|uniprotkb:A2ASM9|uniprotkb:Q3UMQ3|uniprotkb:Q3UYS2 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxd9_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.4(gene name synonym)|uniprotkb:Homeobox protein Hox-5.2(gene name synonym)|uniprotkb:Hoxd9(gene name)|psi-mi:Hoxd9(display_short)|uniprotkb:Hox-4.4(gene name synonym)|uniprotkb:Hoxd-9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681659|imex:IM-28774-3465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) ensembl:ENSMUSG00000043342(gene)|ensembl:ENSMUST00000059272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_038583.1|entrezgene/locuslink:15438(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:yAO/qVdMO1kp4tqqEXeQlloLpOU10090 rigid:oacVddRi64P5vCZDWJWr4pKkwIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P10628 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-26671059|ensembl:ENSMUSP00000047949|ensembl:ENSMUSP00000107611|uniprotkb:A2ASN3|uniprotkb:P97451|uniprotkb:Q3UXL6 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxd4_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.2(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym)|uniprotkb:Hoxd4(gene name)|psi-mi:Hoxd4(display_short)|uniprotkb:Hox-4.2(gene name synonym)|uniprotkb:Hoxd-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681651|imex:IM-28774-809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) ensembl:ENSMUST00000047904(transcript)|ensembl:ENSMUST00000111980(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|ensembl:ENSMUSG00000101174(gene)|refseq:NP_034599.2|entrezgene/locuslink:15436(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:ZxWKuuDpzZjmGsfihJsfPo0M42Q10090 rigid:Bbrh2pbHbK2Gb3Nh8K4O7B8CzFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P23812 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681643|imex:IM-28774-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:iFHDfc80Cx9NTepoRs9WeuVv4wI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P32043 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-26671019|ensembl:ENSMUSP00000001709|uniprotkb:Q8BJW4 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxc5_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.4(gene name synonym)|uniprotkb:Homeobox protein Hox-6.2(gene name synonym)|uniprotkb:Hoxc5(gene name)|psi-mi:Hoxc5(display_short)|uniprotkb:Hox-3.4(gene name synonym)|uniprotkb:Hoxc-5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681635|imex:IM-28774-807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) ensembl:ENSMUSG00000022485(gene)|ensembl:ENSMUST00000001709(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_783857.1|entrezgene/locuslink:15424(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:4uFRMqqb32OVMPfabQFEoqe9KFk10090 rigid:ZoyeY4Vh57oVHCLlcLZVJTy7vcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P09632 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681627|imex:IM-28774-3037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:ZdPpoAaTl9gpI4gNT98dHxWG74Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P09631 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681619|imex:IM-28774-3035 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:xKoOEdzEJVKWPd0kSfl4qIWh/Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P09092 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-26668838|ensembl:ENSMUSP00000058755|uniprotkb:Q9JI98 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxa6_mouse(display_long)|uniprotkb:Homeobox protein Hox-1.2(gene name synonym)|uniprotkb:Homeobox protein M5-4(gene name synonym)|uniprotkb:Hoxa6(gene name)|psi-mi:Hoxa6(display_short)|uniprotkb:Hox-1.2(gene name synonym)|uniprotkb:Hoxa-6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681611|imex:IM-28774-1303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) ensembl:ENSMUSG00000043219(gene)|ensembl:ENSMUST00000062829(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_034584.1|entrezgene/locuslink:15403(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:h4344WEVFSGp7m6UWPSAQn7hIVU10090 rigid:bfQm0n+YOyriiZWPHhRz1JVpnxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P31311 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-445941|uniprotkb:Q3V026|ensembl:ENSMUSP00000040920 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:hxa11_mouse(display_long)|uniprotkb:Hoxa11(gene name)|psi-mi:Hoxa11(display_short)|uniprotkb:Hox-1.9(gene name synonym)|uniprotkb:Hoxa-11(gene name synonym)|uniprotkb:Homeobox protein Hox-1.9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681603|imex:IM-28774-2619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) refseq:NP_034580.1|ensembl:ENSMUSG00000038210(gene)|ensembl:ENSMUST00000048026(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010720"(positive regulation of cell development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048589"(developmental growth)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060065"(uterus development)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR021918|entrezgene/locuslink:15396(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:xmuaYwHq6mzn6Qbx/zJIcMkoNsk10090 rigid:v1O8IZ5jxfq1zLdltE3BfccQEsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6IQX8 uniprotkb:Q07279 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681595|imex:IM-28774-805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1|entrezgene/locuslink:69890(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:R3my1wVwm+zJ/PBBXnGaH5rg7mo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UA06 uniprotkb:Q3UA06 intact:EBI-308990|uniprotkb:A0JNT8|uniprotkb:Q05CL4|uniprotkb:Q3UQG6|uniprotkb:Q9CWW8|ensembl:ENSMUSP00000022053 intact:EBI-308990|uniprotkb:A0JNT8|uniprotkb:Q05CL4|uniprotkb:Q3UQG6|uniprotkb:Q9CWW8|ensembl:ENSMUSP00000022053 psi-mi:pch2_mouse(display_long)|uniprotkb:Trip13(gene name)|psi-mi:Trip13(display_short)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Pch2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym) psi-mi:pch2_mouse(display_long)|uniprotkb:Trip13(gene name)|psi-mi:Trip13(display_short)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Pch2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681579|imex:IM-28774-1723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081458.1|ensembl:ENSMUSG00000021569(gene)|ensembl:ENSMUST00000022053(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|entrezgene/locuslink:69716(identity) refseq:NP_081458.1|ensembl:ENSMUSG00000021569(gene)|ensembl:ENSMUST00000022053(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|entrezgene/locuslink:69716(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VyTQoaPmHJT2nvfJdg00WZVnhkI10090 rogid:VyTQoaPmHJT2nvfJdg00WZVnhkI10090 rigid:at3Vn4CbnjQ4r+edqJmP9WVAbiA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UA06 uniprotkb:Q9WUQ2 intact:EBI-308990|uniprotkb:A0JNT8|uniprotkb:Q05CL4|uniprotkb:Q3UQG6|uniprotkb:Q9CWW8|ensembl:ENSMUSP00000022053 intact:EBI-2553903|uniprotkb:Q9QZ99|ensembl:ENSMUSP00000074387 psi-mi:pch2_mouse(display_long)|uniprotkb:Trip13(gene name)|psi-mi:Trip13(display_short)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Pch2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym) psi-mi:preb_mouse(display_long)|uniprotkb:Sec12(gene name synonym)|uniprotkb:Mammalian guanine nucleotide exchange factor mSec12(gene name synonym)|uniprotkb:Preb(gene name)|psi-mi:Preb(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681571|imex:IM-28774-1721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081458.1|ensembl:ENSMUSG00000021569(gene)|ensembl:ENSMUST00000022053(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|entrezgene/locuslink:69716(identity) refseq:NP_057912.2|ensembl:ENSMUSG00000045302(gene)|ensembl:ENSMUST00000074840(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0009306"(protein secretion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051020"(GTPase binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|mint:Q9WUQ2|reactome:R-MMU-204005|reactome:R-MMU-5694530|entrezgene/locuslink:50907(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VyTQoaPmHJT2nvfJdg00WZVnhkI10090 rogid:jqksMFrLiRmK02t/KLC4ng11UGU10090 rigid:1Inoht2Rqq5xSJOxx8u5YlEDcZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43680 uniprotkb:P27695 intact:EBI-723267|uniprotkb:O43545|uniprotkb:Q9BZ14|ensembl:ENSP00000237316|ensembl:ENSP00000356857|uniprotkb:Q6ICV0|uniprotkb:E1P581 intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979 psi-mi:tcf21_human(display_long)|uniprotkb:Podocyte-expressed 1(gene name synonym)|uniprotkb:Epicardin(gene name synonym)|uniprotkb:Capsulin(gene name synonym)|uniprotkb:TCF21(gene name)|psi-mi:TCF21(display_short)|uniprotkb:POD1(gene name synonym)|uniprotkb:BHLHA23(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 23(gene name synonym) psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681563|imex:IM-28774-1719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003197.2|refseq:NP_938206.1|ensembl:ENSG00000118526(gene)|ensembl:ENST00000237316(transcript)|ensembl:ENST00000367882(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032502"(developmental process)|go:"GO:0032835"(glomerulus development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048536"(spleen development)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060426"(lung vasculature development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060539"(diaphragm development)|go:"GO:0060541"(respiratory system development)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070888"(E-box binding)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072277"(metanephric glomerular capillary formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|entrezgene/locuslink:6943(identity) refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N|entrezgene/locuslink:328(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HM3PKV+KjNvRwhNPBsE5jsuyqd09606 rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606 rigid:Ayqvs32zqK3jitehrBaawcn9E3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43680 uniprotkb:P17509 intact:EBI-723267|uniprotkb:O43545|uniprotkb:Q9BZ14|ensembl:ENSP00000237316|ensembl:ENSP00000356857|uniprotkb:Q6ICV0|uniprotkb:E1P581 intact:EBI-741308|ensembl:ENSP00000225648|ensembl:ENSP00000420009|uniprotkb:P09068|uniprotkb:Q9HB11|uniprotkb:Q9UGH2|uniprotkb:A8K835|uniprotkb:D3DTV5 psi-mi:tcf21_human(display_long)|uniprotkb:Podocyte-expressed 1(gene name synonym)|uniprotkb:Epicardin(gene name synonym)|uniprotkb:Capsulin(gene name synonym)|uniprotkb:TCF21(gene name)|psi-mi:TCF21(display_short)|uniprotkb:POD1(gene name synonym)|uniprotkb:BHLHA23(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 23(gene name synonym) psi-mi:hxb6_human(display_long)|uniprotkb:Homeobox protein Hox-2B(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein Hu-2(gene name synonym)|uniprotkb:HOXB6(gene name)|psi-mi:HOXB6(display_short)|uniprotkb:HOX2B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681555|imex:IM-28774-3463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003197.2|refseq:NP_938206.1|ensembl:ENSG00000118526(gene)|ensembl:ENST00000237316(transcript)|ensembl:ENST00000367882(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032502"(developmental process)|go:"GO:0032835"(glomerulus development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048536"(spleen development)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060426"(lung vasculature development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060539"(diaphragm development)|go:"GO:0060541"(respiratory system development)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070888"(E-box binding)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072277"(metanephric glomerular capillary formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|entrezgene/locuslink:6943(identity) go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P17509|ensembl:ENSG00000108511(gene)|ensembl:ENST00000225648(transcript)|ensembl:ENST00000484302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_061825.2|refseq:XP_005257340.1|refseq:XP_005257341.1|entrezgene/locuslink:3216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HM3PKV+KjNvRwhNPBsE5jsuyqd09606 rogid:5MTUEA03jhudRW4zALviuhMFPPc9606 rigid:lZepA+9jVVEwm0r723zIqKuU6Mk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99081 uniprotkb:Q16559 intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1 intact:EBI-10237959|uniprotkb:A0AVI7|ensembl:ENSP00000334547 psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym) psi-mi:tal2_human(display_long)|uniprotkb:TAL2(gene name)|psi-mi:TAL2(display_short)|uniprotkb:BHLHA19(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681547|imex:IM-28774-1717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628|entrezgene/locuslink:6938(identity) refseq:NP_005412.1|ensembl:ENSG00000186051(gene)|ensembl:ENST00000334077(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|entrezgene/locuslink:6887(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606 rogid:JgO8ZFHP9X70qLk3jzH1SbU+xiU9606 rigid:/a6ceEWjcZK6WGf60eI0jV1OVV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99081 uniprotkb:Q02535 intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681539|imex:IM-28774-803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628|entrezgene/locuslink:6938(identity) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rigid:C1kreqPLLJLPJXkztHdD0XCocrc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99081 uniprotkb:P41134 intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1 intact:EBI-1215527|uniprotkb:O00651|uniprotkb:O00652|uniprotkb:Q16371|uniprotkb:Q16377|uniprotkb:Q5TE66|uniprotkb:Q5TE67|uniprotkb:Q969Z7|uniprotkb:Q9H0Z5|uniprotkb:Q9H109|uniprotkb:A8K537|uniprotkb:E1P5L4|ensembl:ENSP00000365280 psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym) psi-mi:id1_human(display_long)|uniprotkb:ID1(gene name)|psi-mi:ID1(display_short)|uniprotkb:ID(gene name synonym)|uniprotkb:Inhibitor of DNA binding 1(gene name synonym)|uniprotkb:BHLHB24(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 24(gene name synonym)|uniprotkb:Inhibitor of differentiation 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681531|imex:IM-28774-3461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628|entrezgene/locuslink:6938(identity) refseq:NP_002156.2|refseq:NP_851998.1|dip:DIP-38112N|ensembl:ENSG00000125968(gene)|ensembl:ENST00000376112(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036164"(cell-abiotic substrate adhesion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070628"(proteasome binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901342"(regulation of vasculature development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:P41134|reactome:R-HSA-2559585|reactome:R-HSA-9031628|entrezgene/locuslink:3397(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606 rogid:IVXAJsAnQLB8hVutO0qX4bS8gXM9606 rigid:4p0iTjYWCAfzTXD1vEgStRsWT5M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35680 uniprotkb:P61457 intact:EBI-2798841|uniprotkb:B4DKM3|uniprotkb:E0YMJ9|ensembl:ENSP00000480291|ensembl:ENSP00000484591 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:hnf1b_human(display_long)|uniprotkb:TCF2(gene name synonym)|uniprotkb:Homeoprotein LFB3(gene name synonym)|uniprotkb:Transcription factor 2(gene name synonym)|uniprotkb:Variant hepatic nuclear factor 1(gene name synonym)|uniprotkb:HNF1B(gene name)|psi-mi:HNF1B(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681523|imex:IM-28774-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001291215.1|refseq:NP_000449.1|refseq:NP_001159395.1|ensembl:ENSP00000484591|ensembl:ENSP00000480291|ensembl:ENST00000621123|ensembl:ENSP00000482711|ensembl:ENST00000633792|ensembl:ENSP00000488080|rcsb pdb:2H8R|rcsb pdb:5K9S|reactome:R-HSA-210744|reactome:R-HSA-210747|interpro:IPR023219|interpro:IPR039066|rcsb pdb:2DA6|ensembl:ENSG00000275410(gene)|ensembl:ENSG00000276194(gene)|ensembl:ENST00000610754(transcript)|ensembl:ENST00000617811(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030073"(insulin secretion)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035565"(regulation of pronephros size)|go:"GO:0039020"(pronephric nephron tubule development)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048793"(pronephros development)|go:"GO:0048806"(genitalia development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070365"(hepatocyte differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|entrezgene/locuslink:6928(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:t3hSeH5ghgGhsxteLE9W7hBZZrU9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:67e/YStn0aJyd9ynQaovWv6aiCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35680 uniprotkb:P61457 intact:EBI-2798841|uniprotkb:B4DKM3|uniprotkb:E0YMJ9|ensembl:ENSP00000480291|ensembl:ENSP00000484591 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:hnf1b_human(display_long)|uniprotkb:TCF2(gene name synonym)|uniprotkb:Homeoprotein LFB3(gene name synonym)|uniprotkb:Transcription factor 2(gene name synonym)|uniprotkb:Variant hepatic nuclear factor 1(gene name synonym)|uniprotkb:HNF1B(gene name)|psi-mi:HNF1B(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681515|imex:IM-28774-1301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001291215.1|refseq:NP_000449.1|refseq:NP_001159395.1|ensembl:ENSP00000484591|ensembl:ENSP00000480291|ensembl:ENST00000621123|ensembl:ENSP00000482711|ensembl:ENST00000633792|ensembl:ENSP00000488080|rcsb pdb:2H8R|rcsb pdb:5K9S|reactome:R-HSA-210744|reactome:R-HSA-210747|interpro:IPR023219|interpro:IPR039066|rcsb pdb:2DA6|ensembl:ENSG00000275410(gene)|ensembl:ENSG00000276194(gene)|ensembl:ENST00000610754(transcript)|ensembl:ENST00000617811(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030073"(insulin secretion)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035565"(regulation of pronephros size)|go:"GO:0039020"(pronephric nephron tubule development)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048793"(pronephros development)|go:"GO:0048806"(genitalia development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070365"(hepatocyte differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|entrezgene/locuslink:6928(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:t3hSeH5ghgGhsxteLE9W7hBZZrU9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:67e/YStn0aJyd9ynQaovWv6aiCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15370 uniprotkb:Q15369 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681491|imex:IM-28774-1299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N|entrezgene/locuslink:6923(identity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N|entrezgene/locuslink:6921(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:ChwdlwnjrWMP/3O5qvrcyJG5Ytw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CGW9 uniprotkb:Q8R0B5 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 intact:EBI-26670824|ensembl:ENSMUSP00000112532 psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681954|imex:IM-28774-1733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rigid:NuH+IDRwQBUZyCCteS47Fw4BH2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14186 uniprotkb:O75461 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681683|imex:IM-28774-1307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|entrezgene/locuslink:7027(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|entrezgene/locuslink:1876(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:RzW5rWBfoDIXYPuez3Gyh0kR+ig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06537 uniprotkb:Q8CGW9 intact:EBI-492753|uniprotkb:Q61628|uniprotkb:Q61629|ensembl:ENSMUSP00000025300|ensembl:ENSMUSP00000095199|ensembl:ENSMUSP00000111229|ensembl:ENSMUSP00000111233|intact:EBI-26668912|uniprotkb:E9PUR6|uniprotkb:E0ZPU5|uniprotkb:Q06VW2|uniprotkb:Q3U126|uniprotkb:Q3U2M7|uniprotkb:E9PYV1 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 psi-mi:gcr_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym)|uniprotkb:Grl1(gene name synonym) psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681938|imex:IM-28774-819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024431(gene)|ensembl:ENSMUST00000025300(transcript)|ensembl:ENSMUST00000097592(transcript)|ensembl:ENSMUST00000115567(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|ensembl:ENSMUST00000115571(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|reactome:R-MMU-3371497|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048096"|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P06537|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|refseq:NP_032199.3|refseq:XP_006525721.1|refseq:XP_006525722.1|refseq:XP_006525723.1|refseq:XP_006525724.1|refseq:XP_006525725.1|refseq:XP_006525726.1|refseq:XP_006525727.1|refseq:XP_006525728.1|refseq:XP_006525729.1|refseq:XP_017173324.1|refseq:XP_017173325.1|refseq:XP_017173326.1|refseq:XP_017173327.1|dip:DIP-11N|entrezgene/locuslink:14815(identity) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/11/30 rogid:BGeJbz2zNEPZBn4cdswdbgRBif410090 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rigid:FNOvjels/S+0Mi4l9tIkbE4pXeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TNK1 uniprotkb:P15806 intact:EBI-26681892|ensembl:ENSMUSP00000051107|uniprotkb:B2RS52|uniprotkb:Q3V158|uniprotkb:Q76KT2|uniprotkb:Q8HWA6|uniprotkb:Q9D453 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:rfx4_mouse(display_long)|uniprotkb:Regulatory factor X 4(gene name synonym)|uniprotkb:Rfx4(gene name)|psi-mi:Rfx4(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681930|imex:IM-28774-1311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020037(gene)|ensembl:ENSMUST00000060397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021537"(telencephalon development)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|refseq:NP_001020089.1|refseq:NP_081965.2|entrezgene/locuslink:71137(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8V+H6zUYVwJumq/V+zqYJLQevb410090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:/ZMzzFkcQhxHZlkZw5bjeCgxKsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04725 uniprotkb:P55771 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681884|imex:IM-28774-1309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:ezVcqJKXnMq1vdpwtBjWNmzOOwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35548 uniprotkb:Q04725 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681876|imex:IM-28774-2625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rigid:fREFGBRl4SSBFhLdOeHvZAPmX0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04725 uniprotkb:P28360 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-3919342|ensembl:ENSP00000372170|uniprotkb:Q96NY4|uniprotkb:A0SZU5|uniprotkb:A8K3M1 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:msx1_human(display_long)|uniprotkb:MSX1(gene name)|psi-mi:MSX1(display_short)|uniprotkb:HOX7(gene name synonym)|uniprotkb:Homeobox protein Hox-7(gene name synonym)|uniprotkb:Msh homeobox 1-like protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681868|imex:IM-28774-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001055"(positive regulation of mesenchymal cell apoptotic process)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|ensembl:ENSG00000163132(gene)|ensembl:ENST00000382723(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010463"(mesenchymal cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035880"(embryonic nail plate morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042481"(regulation of odontogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0061312"(BMP signaling pathway involved in heart development)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090427"(activation of meiosis)|go:"GO:0030308"(negative regulation of cell growth)|refseq:NP_002439.2|entrezgene/locuslink:4487(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:moD9wVPS7gbE9d0VPHu/atQijKs9606 rigid:IAOUpCFdfhovg0DF2L27Ko4oeAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04725 uniprotkb:P55318 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-3910364|uniprotkb:A9LYI5|uniprotkb:Q53F16|uniprotkb:Q9UMW9|ensembl:ENSP00000304004 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:foxa3_human(display_long)|uniprotkb:FOXA3(gene name)|psi-mi:FOXA3(display_short)|uniprotkb:HNF3G(gene name synonym)|uniprotkb:TCF3G(gene name synonym)|uniprotkb:Fork head-related protein FKH H3(gene name synonym)|uniprotkb:Forkhead box protein A3(gene name synonym)|uniprotkb:Transcription factor 3G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681860|imex:IM-28774-3041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) refseq:NP_004488.2|ensembl:ENSG00000170608(gene)|ensembl:ENST00000302177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1VTN|reactome:R-HSA-210745|entrezgene/locuslink:3171(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:n02J7Tp+VDpup25KyiVjbGur1Sg9606 rigid:cPIk2Qz4Dv0ZTfZ9j+bpZlZfs5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04725 uniprotkb:Q04743 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-399831|uniprotkb:Q96NN8|uniprotkb:Q9BQF4|uniprotkb:G3V305|ensembl:ENSP00000450962 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:emx2_human(display_long)|uniprotkb:EMX2(gene name)|psi-mi:EMX2(display_short)|uniprotkb:Empty spiracles homolog 2(gene name synonym)|uniprotkb:Empty spiracles-like protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681852|imex:IM-28774-1731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|entrezgene/locuslink:7089(identity) refseq:NP_001159396.1|refseq:NP_004089.1|ensembl:ENSG00000170370(gene)|ensembl:ENST00000553456(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021885"(forebrain cell migration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0072197"(ureter morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:2018(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:+b7ChE+6RlzUb0sr/8vnDFtFy2c9606 rigid:UUgWtGcp2z8Bgi2nN4ktfrEuGho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04724 uniprotkb:P55771 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681844|imex:IM-28774-817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:UHQLau+AfPbgY5/qMJp8DBT7R3s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35548 uniprotkb:Q04724 intact:EBI-6447480|ensembl:ENSP00000239243|uniprotkb:Q9UD60|uniprotkb:D3DQN1|uniprotkb:Q53XM4 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:msx2_human(display_long)|uniprotkb:HOX8(gene name synonym)|uniprotkb:Homeobox protein Hox-8(gene name synonym)|uniprotkb:MSX2(gene name)|psi-mi:MSX2(display_short) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681836|imex:IM-28774-815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120149(gene)|ensembl:ENST00000239243(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|reactome:R-HSA-8939902|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_002440.2|entrezgene/locuslink:4488(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:CwJv3r6WEjsntzZp0tQCVwG3nkw9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:v21EXhIrCcrUYSa+z4sZ1VqfLmk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04724 uniprotkb:O43763 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681828|imex:IM-28774-1729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:wHEyxr/vbfmzA1nQHWjHA22vGyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04724 uniprotkb:P55318 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 intact:EBI-3910364|uniprotkb:A9LYI5|uniprotkb:Q53F16|uniprotkb:Q9UMW9|ensembl:ENSP00000304004 psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:foxa3_human(display_long)|uniprotkb:FOXA3(gene name)|psi-mi:FOXA3(display_short)|uniprotkb:HNF3G(gene name synonym)|uniprotkb:TCF3G(gene name synonym)|uniprotkb:Fork head-related protein FKH H3(gene name synonym)|uniprotkb:Forkhead box protein A3(gene name synonym)|uniprotkb:Transcription factor 3G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681820|imex:IM-28774-3039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) refseq:NP_004488.2|ensembl:ENSG00000170608(gene)|ensembl:ENST00000302177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1VTN|reactome:R-HSA-210745|entrezgene/locuslink:3171(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rogid:n02J7Tp+VDpup25KyiVjbGur1Sg9606 rigid:ni05YAT3g75h6gjsItluV3yUWKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y261 uniprotkb:Q04724 intact:EBI-7255248|ensembl:ENSP00000366319|uniprotkb:Q8WUW4|uniprotkb:Q96DF7|intact:MINT-6610868 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:foxa2_human(display_long)|uniprotkb:FOXA2(gene name)|psi-mi:FOXA2(display_short)|uniprotkb:HNF3B(gene name synonym)|uniprotkb:TCF3B(gene name synonym)|uniprotkb:Forkhead box protein A2(gene name synonym)|uniprotkb:Transcription factor 3B(gene name synonym) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681812|imex:IM-28774-2185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125798(gene)|ensembl:ENST00000377115(transcript)|go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061987"(negative regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000971"(negative regulation of detection of glucose)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR018533|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:Q9Y261|rcsb pdb:5X07|reactome:R-HSA-210745|refseq:NP_710141.1|refseq:NP_068556.2|entrezgene/locuslink:3170(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - comment:mint|function:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4vF1YSzaAH8U/smjaLjSC3MS2sQ9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:hiqiB8OPFzcwkSzTNCF0hselZ9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04724 uniprotkb:P55317 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 intact:EBI-3918034|uniprotkb:Q9H2A0|uniprotkb:B2R9H6|ensembl:ENSP00000250448|uniprotkb:B7ZAP5 psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:foxa1_human(display_long)|uniprotkb:FOXA1(gene name)|psi-mi:FOXA1(display_short)|uniprotkb:HNF3A(gene name synonym)|uniprotkb:TCF3A(gene name synonym)|uniprotkb:Forkhead box protein A1(gene name synonym)|uniprotkb:Transcription factor 3A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681804|imex:IM-28774-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) refseq:NP_004487.2|ensembl:ENSG00000129514(gene)|ensembl:ENST00000250448(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030154"(cell differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060738"(epithelial-mesenchymal signaling involved in prostate gland development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060741"(prostate gland stromal morphogenesis)|go:"GO:0060743"(epithelial cell maturation involved in prostate gland development)|go:"GO:0061144"(alveolar secondary septum development)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1902691"(respiratory basal cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR018533|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:P55317|reactome:R-HSA-9018519|refseq:XP_016876735.1|dip:DIP-57138N|entrezgene/locuslink:3169(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rogid:RX9LFKwRrO2a2X9hXpHbZdcMpZE9606 rigid:FPMMslA0MevPDv8PYjlmudU2OoE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04724 uniprotkb:P52952 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 intact:EBI-936601|uniprotkb:A8K3K0|uniprotkb:B4DNB6|uniprotkb:E9PBU6|ensembl:ENSP00000327758 psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:nkx25_human(display_long)|uniprotkb:NKX2-5(gene name)|psi-mi:NKX2-5(display_short)|uniprotkb:CSX(gene name synonym)|uniprotkb:NKX2.5(gene name synonym)|uniprotkb:NKX2E(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog E(gene name synonym)|uniprotkb:Cardiac-specific homeobox(gene name synonym)|uniprotkb:Homeobox protein CSX(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681796|imex:IM-28774-813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) refseq:NP_001159647.1|refseq:NP_001159648.1|refseq:NP_004378.1|ensembl:ENSG00000183072(gene)|ensembl:ENST00000329198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003166"(bundle of His development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003221"(right ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003228"(atrial cardiac muscle tissue development)|go:"GO:0003285"(septum secundum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007512"(adult heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033629|rcsb pdb:3RKQ|rcsb pdb:4S0H|rcsb pdb:6WC2|rcsb pdb:6WC5|reactome:R-HSA-2032785|reactome:R-HSA-5578768|entrezgene/locuslink:1482(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rogid:wLSYYxUoPmhRfcbEfCdGPPv4qCQ9606 rigid:2W0wJ8UHgWnAaQaaqJzpSuC40BM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CXE0 uniprotkb:P25425 intact:EBI-26681756|ensembl:ENSMUSP00000031976|uniprotkb:B2RSK8 intact:EBI-16577687|uniprotkb:Q61994|uniprotkb:Q63891|uniprotkb:Q6Y681|uniprotkb:Q7TSD0|uniprotkb:Q8BT04|uniprotkb:Q8K570|uniprotkb:Q99JH0|uniprotkb:Q9WTZ4|uniprotkb:Q9WTZ5|uniprotkb:Q9WTZ6 psi-mi:prdm5_mouse(display_long)|uniprotkb:PR domain-containing protein 5(gene name synonym)|uniprotkb:Prdm5(gene name)|psi-mi:Prdm5(display_short) psi-mi:po2f1_mouse(display_long)|uniprotkb:Pou2f1(gene name)|psi-mi:Pou2f1(display_short)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:Oct-1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:Otf-1(gene name synonym)|uniprotkb:Otf1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681788|imex:IM-28774-811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029913(gene)|ensembl:ENSMUST00000031976(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017125(PR-domain zinc finger protein PRDM5)|interpro:IPR036236|interpro:IPR044415|refseq:NP_081823.2|entrezgene/locuslink:70779(identity) reactome:R-MMU-9018519|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000327(POU-specific)|interpro:IPR000972(Octamer-binding transcription factor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR017970|reactome:R-MMU-6807505|reactome:R-MMU-76071|refseq:NP_035267.2|refseq:NP_945151.2|refseq:XP_006496767.1|refseq:XP_011237069.1|refseq:XP_011237071.1|refseq:XP_017174849.1|entrezgene/locuslink:18986(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:c2232NI15L7Mvl+1ojFnJEHQMfc10090 rogid:IMDuy3TILCw6JtyVfthlE0e4Xrw10090 rigid:mDnvaE+DTYNsRvurNycpulpDZnw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921X6 uniprotkb:Q9WUL8 intact:EBI-26681707|ensembl:ENSMUSP00000028914|uniprotkb:Q544K6 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:rpc6_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase III subunit F(gene name synonym)|uniprotkb:Polr3f(gene name)|psi-mi:Polr3f(display_short) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681748|imex:IM-28774-1727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027427(gene)|ensembl:ENSMUST00000028914(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007832(RNA polymerase Rpc34)|interpro:IPR016049(RNA polymerase Rpc34-like)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DK8|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|refseq:NP_084039.2|entrezgene/locuslink:70408(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nLMn1tl/eZWzexeEKuAvu+Q0mgI10090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:KbZA/QTOi6EGvr6V4+5i2AMEA0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921X6 uniprotkb:Q05BA5 intact:EBI-26681707|ensembl:ENSMUSP00000028914|uniprotkb:Q544K6 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:rpc6_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase III subunit F(gene name synonym)|uniprotkb:Polr3f(gene name)|psi-mi:Polr3f(display_short) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681740|imex:IM-28774-2623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027427(gene)|ensembl:ENSMUST00000028914(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007832(RNA polymerase Rpc34)|interpro:IPR016049(RNA polymerase Rpc34-like)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DK8|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|refseq:NP_084039.2|entrezgene/locuslink:70408(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nLMn1tl/eZWzexeEKuAvu+Q0mgI10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:QYYqhr/i+ZDN6U/LOzoNIYzHKV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q921X6 uniprotkb:Q61545 intact:EBI-26681707|ensembl:ENSMUSP00000028914|uniprotkb:Q544K6 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rpc6_mouse(display_long)|uniprotkb:DNA-directed RNA polymerase III subunit F(gene name synonym)|uniprotkb:Polr3f(gene name)|psi-mi:Polr3f(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681732|imex:IM-28774-3469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027427(gene)|ensembl:ENSMUST00000028914(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007832(RNA polymerase Rpc34)|interpro:IPR016049(RNA polymerase Rpc34-like)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2DK8|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|refseq:NP_084039.2|entrezgene/locuslink:70408(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nLMn1tl/eZWzexeEKuAvu+Q0mgI10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:MbiTlDG85GgFN9z+Z/FyX9NCwNw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D738 uniprotkb:Q07279 intact:EBI-26673456|ensembl:ENSMUSP00000033549 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:asb12_mouse(display_long)|uniprotkb:Asb12(gene name)|psi-mi:Asb12(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681699|imex:IM-28774-3467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031204(gene)|ensembl:ENSMUST00000033549(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001300672.1|refseq:NP_543134.1|refseq:XP_011245976.1|entrezgene/locuslink:70392(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mChKqzsKJHIjzxkuW5hR0ISRT1g10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:IidQ2CcQbs4Rx18Q1sR99Sg5agk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D738 uniprotkb:P31245 intact:EBI-26673456|ensembl:ENSMUSP00000033549 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:asb12_mouse(display_long)|uniprotkb:Asb12(gene name)|psi-mi:Asb12(display_short) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681691|imex:IM-28774-2621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031204(gene)|ensembl:ENSMUST00000033549(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_001300672.1|refseq:NP_543134.1|refseq:XP_011245976.1|entrezgene/locuslink:70392(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:mChKqzsKJHIjzxkuW5hR0ISRT1g10090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:xwaglmuVuKcifn7pT3JroZnyyGk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CGW9 uniprotkb:P97311 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 intact:EBI-457132|uniprotkb:Q80YQ7|ensembl:ENSMUSP00000027601 psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:mcm6_mouse(display_long)|uniprotkb:Mis5 homolog(gene name synonym)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:Mcmd6(gene name synonym)|uniprotkb:Mis5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681946|imex:IM-28774-3471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) refseq:NP_032593.1|ensembl:ENSMUSG00000026355(gene)|ensembl:ENSMUST00000027601(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|mint:P97311|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052|entrezgene/locuslink:17219(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rogid:JwuQj25XyutAyROxAkOr/NyIjCA10090 rigid:OeSzUeeu0wGh4PO3blqCu8KQAdg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q8CFD5 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682183|imex:IM-28774-1735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rigid:GC5z0nQBIm/zGNmfRDAk0TFNf2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CGW9 uniprotkb:Q3U1N2 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 intact:EBI-645275|uniprotkb:Q9ESZ4|uniprotkb:Q925C2|ensembl:ENSMUSP00000023100 psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:srbp2_mouse(display_long)|uniprotkb:Sterol regulatory element-binding transcription factor 2(gene name synonym)|uniprotkb:Srebf2(gene name)|psi-mi:Srebf2(display_short)|uniprotkb:Srebp2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681963|imex:IM-28774-2627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) refseq:NP_150087.1|ensembl:ENSMUSG00000022463(gene)|ensembl:ENSMUST00000023100(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009725"(response to hormone)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-MMU-1655829|go:"GO:0008593"(regulation of Notch signaling pathway)|entrezgene/locuslink:20788(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rogid:uDjwj6tUHAmJizC11vcpYHK/sUc10090 rigid:M8eh4BsjKbAtayN5V3L6xO4uoJ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0P5 uniprotkb:O55203 intact:EBI-8607760|ensembl:ENSMUSP00000044368|intact:MINT-8177753 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:pygo1_mouse(display_long)|uniprotkb:Pygo1(gene name)|psi-mi:Pygo1(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682257|imex:IM-28774-1321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034910(gene)|ensembl:ENSMUST00000038489(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|rcsb pdb:2DX8|rcsb pdb:2YYR|reactome:R-MMU-201722|interpro:IPR019786|refseq:NP_082392.1|entrezgene/locuslink:72135(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - comment:mint "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcuyU94M5VkU3ooZ8t9278flbd410090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:ru+s1Os1aFGCotPZk1jC+6JabTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0P5 uniprotkb:P70662 intact:EBI-8607760|ensembl:ENSMUSP00000044368|intact:MINT-8177753 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:pygo1_mouse(display_long)|uniprotkb:Pygo1(gene name)|psi-mi:Pygo1(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682249|imex:IM-28774-2191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034910(gene)|ensembl:ENSMUST00000038489(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|rcsb pdb:2DX8|rcsb pdb:2YYR|reactome:R-MMU-201722|interpro:IPR019786|refseq:NP_082392.1|entrezgene/locuslink:72135(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcuyU94M5VkU3ooZ8t9278flbd410090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:KMwVxCM5lTQXpGgGq/oCWuuuUzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFD5 uniprotkb:P15806 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682232|imex:IM-28774-1737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:bqbJzqm3VAVxlPZYMxsdn038/PA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFD5 uniprotkb:Q07279 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682215|imex:IM-28774-2631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:Xx+CzqOYKgbA2DYSiZhIYy7pfsY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFD5 uniprotkb:Q05BA5 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682207|imex:IM-28774-1319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:kL/nZh+FJKIoL/tYB5ScNjULjZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFD5 uniprotkb:P31245 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682199|imex:IM-28774-823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:XTAfeew0eBUlPVsUiJu5Sq811wI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFD5 uniprotkb:Q61545 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682191|imex:IM-28774-2189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:gZSAuOoxavzUAZ1slxKP1jWdILc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0P5 uniprotkb:Q9CYZ8 intact:EBI-8607760|ensembl:ENSMUSP00000044368|intact:MINT-8177753 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:pygo1_mouse(display_long)|uniprotkb:Pygo1(gene name)|psi-mi:Pygo1(display_short) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682273|imex:IM-28774-3479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034910(gene)|ensembl:ENSMUST00000038489(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|rcsb pdb:2DX8|rcsb pdb:2YYR|reactome:R-MMU-201722|interpro:IPR019786|refseq:NP_082392.1|entrezgene/locuslink:72135(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcuyU94M5VkU3ooZ8t9278flbd410090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:z+5+oIVntkHapiFh6kosjaHbHaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CFD5 uniprotkb:O35137 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-26667512|ensembl:ENSMUSP00000047962 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:alx4_mouse(display_long)|uniprotkb:ALX-4(gene name synonym)|uniprotkb:Alx4(gene name)|psi-mi:Alx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682166|imex:IM-28774-1317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033203|go:"GO:0071837"(HMG box domain binding)|ensembl:ENSMUSG00000040310(gene)|ensembl:ENSMUST00000042078(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|refseq:NP_031468.1|entrezgene/locuslink:11695(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:H7gqCBduD2/fBe3foPUlAfmYCHk10090 rigid:l7QisaIjusrJFY+G4h/35FvY1EY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D6K9 uniprotkb:Q9JL10 intact:EBI-26682068|ensembl:ENSMUSP00000023762|uniprotkb:Q3UL17|uniprotkb:Q80YB2|uniprotkb:Q8BPH6|uniprotkb:Q921T8|uniprotkb:Q924Z3 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 psi-mi:cers5_mouse(display_long)|uniprotkb:LAG1 longevity assurance homolog 5(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS5(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 4(gene name synonym)|uniprotkb:Cers5(gene name)|psi-mi:Cers5(display_short)|uniprotkb:Lass5(gene name synonym)|uniprotkb:Trh4(gene name synonym)|uniprotkb:Sphingoid base N-palmitoyltransferase CERS5(gene name synonym) psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682110|imex:IM-28774-1315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000023021(gene)|ensembl:ENSMUST00000023762(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|rcsb pdb:2CQX|rcsb pdb:5E8N|rcsb pdb:5E8O|rcsb pdb:5E8P|reactome:R-MMU-1660661|refseq:NP_082291.1|entrezgene/locuslink:71949(identity) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:z4swZkbMyG1m6bkAxAl2SaXnrEA10090 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rigid:t4rzDLcpFtf+3OSeWXU8KvPDS/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D6K9 uniprotkb:Q61545 intact:EBI-26682068|ensembl:ENSMUSP00000023762|uniprotkb:Q3UL17|uniprotkb:Q80YB2|uniprotkb:Q8BPH6|uniprotkb:Q921T8|uniprotkb:Q924Z3 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:cers5_mouse(display_long)|uniprotkb:LAG1 longevity assurance homolog 5(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS5(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 4(gene name synonym)|uniprotkb:Cers5(gene name)|psi-mi:Cers5(display_short)|uniprotkb:Lass5(gene name synonym)|uniprotkb:Trh4(gene name synonym)|uniprotkb:Sphingoid base N-palmitoyltransferase CERS5(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682102|imex:IM-28774-821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000023021(gene)|ensembl:ENSMUST00000023762(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|rcsb pdb:2CQX|rcsb pdb:5E8N|rcsb pdb:5E8O|rcsb pdb:5E8P|reactome:R-MMU-1660661|refseq:NP_082291.1|entrezgene/locuslink:71949(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:z4swZkbMyG1m6bkAxAl2SaXnrEA10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:yN7gjNtbST6Cfym2/yGc4zt2TMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:Q9QZ28 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-348987|uniprotkb:O88423|ensembl:ENSMUSP00000021519 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:six6_mouse(display_long)|uniprotkb:Six6(gene name)|psi-mi:Six6(display_short)|uniprotkb:Optx2(gene name synonym)|uniprotkb:Six9(gene name synonym)|uniprotkb:Sine oculis homeobox homolog 6(gene name synonym)|uniprotkb:Optic homeobox 2(gene name synonym)|uniprotkb:Six9 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682060|imex:IM-28774-1313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) refseq:NP_035514.1|ensembl:ENSMUSG00000021099(gene)|ensembl:ENSMUST00000021519(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR031701|interpro:IPR032947|entrezgene/locuslink:20476(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:LE6vGckqrqLOASpqOf6dhsyntYI10090 rigid:RWFAf1QnAlcbmOt4A5FEUq/OIG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:P23812 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682052|imex:IM-28774-2187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:AlKkpWGTVYjbE5jDQPFd3glOmMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:P09632 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-925374|ensembl:ENSMUSP00000052496|ensembl:ENSMUSP00000128136 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hxb8_mouse(display_long)|uniprotkb:Hoxb8(gene name)|psi-mi:Hoxb8(display_short)|uniprotkb:Hox-2.4(gene name synonym)|uniprotkb:Hoxb-8(gene name synonym)|uniprotkb:Homeobox protein Hox-2.4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682044|imex:IM-28774-3475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) refseq:NP_034591.1|refseq:XP_017169784.1|refseq:XP_017169785.1|refseq:XP_017169786.1|dip:DIP-35618N|ensembl:ENSMUSG00000056648(gene)|ensembl:ENSMUST00000052650(transcript)|ensembl:ENSMUST00000168043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007625"(grooming behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15416(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:8LDO2u1q6tdrQsFLAfruV6oK7CE10090 rigid:tpsLW29Rgch5zNuZLgZk+h8lHgU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:P09631 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-925334|uniprotkb:O70154|uniprotkb:O70155|ensembl:ENSMUSP00000046939 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hxa9_mouse(display_long)|uniprotkb:Hoxa9(gene name)|psi-mi:Hoxa9(display_short)|uniprotkb:Hox-1.7(gene name synonym)|uniprotkb:Hoxa-9(gene name synonym)|uniprotkb:Homeobox protein Hox-1.7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682036|imex:IM-28774-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) refseq:NP_034586.1|dip:DIP-35619N|ensembl:ENSMUSG00000038227(gene)|ensembl:ENSMUST00000048680(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1PUF|entrezgene/locuslink:15405(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:OjGwxaxJEuDgDykwUs76pvyWuvU10090 rigid:APBiecmKAH4oAPhL6BmWAJtWbmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:P43120 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-26669953|ensembl:ENSMUSP00000025944|uniprotkb:Q544N6|uniprotkb:Q9CRV1|uniprotkb:Q9R1X2 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:hhex_mouse(display_long)|uniprotkb:Homeobox protein PRH(gene name synonym)|uniprotkb:Hhex(gene name)|psi-mi:Hhex(display_short)|uniprotkb:Prh(gene name synonym)|uniprotkb:Prhx(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682028|imex:IM-28774-3473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) ensembl:ENSMUSG00000024986(gene)|ensembl:ENSMUST00000025944(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007492"(endoderm development)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0060431"(primary lung bud formation)|go:"GO:0061009"(common bile duct development)|go:"GO:0061010"(gall bladder development)|go:"GO:0061011"(hepatic duct development)|go:"GO:0061017"(hepatoblast differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070663"(regulation of leukocyte proliferation)|go:"GO:0071103"(DNA conformation change)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_032271.1|entrezgene/locuslink:15242(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:CFFMI2L8Rr327CW687XQBaotsDQ10090 rigid:Vm+6NdH2Av5Kq7diYRLkXRV7170 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:Q04742 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682020|imex:IM-28774-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:8y9mFZmwNIpx6vKoAPc8xTy9coQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8R4I4 uniprotkb:Q07424 intact:EBI-7640206|ensembl:ENSMUSP00000024970|uniprotkb:Q9DAF4|uniprotkb:Q99PM2|intact:MINT-1348145 intact:EBI-26668214|ensembl:ENSMUSP00000033689 psi-mi:tf2ay_mouse(display_long)|uniprotkb:Alf(gene name synonym)|uniprotkb:Gtf2a1lf(gene name synonym)|uniprotkb:Gtf2a1l(gene name)|psi-mi:Gtf2a1l(display_short)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:cdx4_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 4(gene name synonym)|uniprotkb:Cdx4(gene name)|psi-mi:Cdx4(display_short)|uniprotkb:Cdx-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682012|imex:IM-28774-3045 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024154(gene)|ensembl:ENSMUST00000024970(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|refseq:NP_076119.2|entrezgene/locuslink:71828(identity) ensembl:ENSMUSG00000031326(gene)|ensembl:ENSMUST00000033689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001890"(placenta development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_031700.1|entrezgene/locuslink:12592(identity) - comment:mint|function:"May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yo2Cl+ui7HGZ09BQs7fvPzwQt9w10090 rogid:ZygM/NoxCumicSJlDzHtwO/L33410090 rigid:N0d+8gjedplri02Oyjfd8i3reYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924A2 uniprotkb:G3X904 intact:EBI-8412165|uniprotkb:Q8CGE4|uniprotkb:Q3UH79|uniprotkb:Q6PDJ8|uniprotkb:Q3UHP4|intact:MINT-4122947|uniprotkb:Q8CHH0|uniprotkb:Q9CW61|ensembl:ENSMUSP00000132351 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:cic_mouse(display_long)|uniprotkb:Cic(gene name)|psi-mi:Cic(display_short)|uniprotkb:Kiaa0306(gene name synonym) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682004|imex:IM-28774-2629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289740.1|refseq:NP_082158.2|dip:DIP-60650N|ensembl:ENSMUSG00000005442(gene)|ensembl:ENSMUST00000169266(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035176"(social behavior)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048286"(lung alveolus development)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR032147|interpro:IPR036910|mint:Q924A2|entrezgene/locuslink:71722(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - comment:mint|function:"Transcriptional repressor which may play a role in development of the central nervous system (CNS)" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:j6hI3ZjbB9tv3vrtJvgl6IEIs6410090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:8J+CgD6C8UIVblSe1TLiQ9tQR1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CGW9 uniprotkb:Q925T4 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 intact:EBI-26681971|ensembl:ENSMUSP00000055709|ensembl:ENSMUSP00000105419 psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:q925t4_mouse(display_long)|uniprotkb:Plagl2(gene name)|psi-mi:Plagl2(display_short)|uniprotkb:plagl2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26681996|imex:IM-28774-3043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) ensembl:ENSMUSG00000051413(gene)|ensembl:ENSMUST00000056924(transcript)|ensembl:ENSMUST00000109795(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027765|interpro:IPR036236|refseq:NP_061277.2|entrezgene/locuslink:54711(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rogid:sfId+X6xShRQ1fhdpThnckJUkT010090 rigid:9uAJG3EMusjApe6I/G9zp3gjj9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0P5 uniprotkb:Q9WUH2 intact:EBI-8607760|ensembl:ENSMUSP00000044368|intact:MINT-8177753 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 psi-mi:pygo1_mouse(display_long)|uniprotkb:Pygo1(gene name)|psi-mi:Pygo1(display_short) psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682265|imex:IM-28774-3477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034910(gene)|ensembl:ENSMUST00000038489(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|rcsb pdb:2DX8|rcsb pdb:2YYR|reactome:R-MMU-201722|interpro:IPR019786|refseq:NP_082392.1|entrezgene/locuslink:72135(identity) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcuyU94M5VkU3ooZ8t9278flbd410090 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rigid:P+IgQQ1z+cCCkZQ/tcGJ5amhHQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91ZU1 uniprotkb:Q61545 intact:EBI-26682355|ensembl:ENSMUSP00000043462|uniprotkb:Q8VEC6 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:asb6_mouse(display_long)|uniprotkb:Asb6(gene name)|psi-mi:Asb6(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682375|imex:IM-28774-2635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039483(gene)|ensembl:ENSMUST00000041726(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036036|interpro:IPR036770|interpro:IPR037327|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_579924.1|entrezgene/locuslink:72323(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:40MEhpjj3BvFvKVZzfiNapZ2JYo10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:FuKqT4bYT7rTTJEJwSv/Ubp4fzc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91ZU1 uniprotkb:Q9JL10 intact:EBI-26682355|ensembl:ENSMUSP00000043462|uniprotkb:Q8VEC6 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 psi-mi:asb6_mouse(display_long)|uniprotkb:Asb6(gene name)|psi-mi:Asb6(display_short) psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682383|imex:IM-28774-825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039483(gene)|ensembl:ENSMUST00000041726(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR036036|interpro:IPR036770|interpro:IPR037327|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_579924.1|entrezgene/locuslink:72323(identity) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:40MEhpjj3BvFvKVZzfiNapZ2JYo10090 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rigid:mqpj673e/HZyt5VX3DErGUAmKyE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VE28 uniprotkb:Q61545 intact:EBI-1538490|uniprotkb:Q3TYU5|uniprotkb:Q3UM34|uniprotkb:Q8C4J8|uniprotkb:Q91Y45|uniprotkb:Q9D7U9|ensembl:ENSMUSP00000022051 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:nkd2_mouse(display_long)|uniprotkb:Nkd2(gene name)|psi-mi:Nkd2(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682339|imex:IM-28774-1323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082462.3|refseq:NP_001334464.1|ensembl:ENSMUSG00000021567(gene)|ensembl:ENSMUST00000022051(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140|entrezgene/locuslink:72293(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YahIfIwWuxWNCTmkeFs9nSf8UWc10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:civSpidJw9FkssNTz19h/iSSnnk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D071 uniprotkb:Q07279 intact:EBI-4283533|uniprotkb:Q925N8|uniprotkb:Q9CWX3|uniprotkb:F8WHX3|ensembl:ENSMUSP00000130900 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:mms19_mouse(display_long)|uniprotkb:Mms19(gene name)|psi-mi:Mms19(display_short)|uniprotkb:Mms19l(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682331|imex:IM-28774-2195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082428.1|ensembl:ENSMUSG00000025159(gene)|ensembl:ENSMUST00000171561(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|rcsb pdb:6TBL|rcsb pdb:6TC0|entrezgene/locuslink:72199(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S24j+ddJAniA1XEtuEoZvrT6K7s10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:q6QhtRHdry4U/EHHfbgXW3a6sLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D071 uniprotkb:O54791 intact:EBI-4283533|uniprotkb:Q925N8|uniprotkb:Q9CWX3|uniprotkb:F8WHX3|ensembl:ENSMUSP00000130900 intact:EBI-26682289|ensembl:ENSMUSP00000094076|ensembl:ENSMUSP00000131628|ensembl:ENSMUSP00000154850 psi-mi:mms19_mouse(display_long)|uniprotkb:Mms19(gene name)|psi-mi:Mms19(display_short)|uniprotkb:Mms19l(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym) psi-mi:maff_mouse(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog F(gene name synonym)|uniprotkb:Maff(gene name)|psi-mi:Maff(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682323|imex:IM-28774-2193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082428.1|ensembl:ENSMUSG00000025159(gene)|ensembl:ENSMUST00000171561(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|rcsb pdb:6TBL|rcsb pdb:6TC0|entrezgene/locuslink:72199(identity) ensembl:ENSMUSG00000042622(gene)|ensembl:ENSMUST00000096350(transcript)|ensembl:ENSMUST00000163691(transcript)|ensembl:ENSMUST00000229130(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR033531|reactome:R-MMU-983231|refseq:NP_001291759.1|refseq:NP_034885.1|refseq:XP_006520609.2|refseq:XP_006520613.1|refseq:XP_011243786.1|entrezgene/locuslink:17133(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S24j+ddJAniA1XEtuEoZvrT6K7s10090 rogid:zrmh35o8q9ytxsY/iTU1oRFCfNA10090 rigid:aTCm8i+GAVByL9cROwL2+8LExjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D071 uniprotkb:Q61545 intact:EBI-4283533|uniprotkb:Q925N8|uniprotkb:Q9CWX3|uniprotkb:F8WHX3|ensembl:ENSMUSP00000130900 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:mms19_mouse(display_long)|uniprotkb:Mms19(gene name)|psi-mi:Mms19(display_short)|uniprotkb:Mms19l(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682281|imex:IM-28774-3047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082428.1|ensembl:ENSMUSG00000025159(gene)|ensembl:ENSMUST00000171561(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|rcsb pdb:6TBL|rcsb pdb:6TC0|entrezgene/locuslink:72199(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:S24j+ddJAniA1XEtuEoZvrT6K7s10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:pasZMQVvC7FmdYmSf8AYpglH8Fw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZI7 uniprotkb:Q12800 intact:EBI-2795133|uniprotkb:Q68CT0|uniprotkb:Q86Y57|uniprotkb:Q9H8V0|uniprotkb:Q9UD76|uniprotkb:Q9UD78|ensembl:ENSP00000283628|ensembl:ENSP00000283629 intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915 psi-mi:ubip1_human(display_long)|uniprotkb:UBP1(gene name)|psi-mi:UBP1(display_short)|uniprotkb:LBP1(gene name synonym)|uniprotkb:Transcription factor LBP-1(gene name synonym) psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682519|imex:IM-28774-1743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121632.1|refseq:NP_001121633.1|refseq:NP_055332.3|ensembl:ENSG00000153560(gene)|ensembl:ENST00000283628(transcript)|ensembl:ENST00000283629(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q9NZI7|go:"GO:0032897"(negative regulation of viral transcription)|entrezgene/locuslink:7342(identity) refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aMcHSKF2w0CPIYmoyowV2a3I9Tk9606 rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606 rigid:vzy9pSykpfg98JW0yCDhszIvK58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8CFD5 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682511|imex:IM-28774-3485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rigid:FomgNmN5ja5dJN1If83pj+jG8Ro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q7TNK1 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26681892|ensembl:ENSMUSP00000051107|uniprotkb:B2RS52|uniprotkb:Q3V158|uniprotkb:Q76KT2|uniprotkb:Q8HWA6|uniprotkb:Q9D453 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:rfx4_mouse(display_long)|uniprotkb:Regulatory factor X 4(gene name synonym)|uniprotkb:Rfx4(gene name)|psi-mi:Rfx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682503|imex:IM-28774-3053 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000020037(gene)|ensembl:ENSMUST00000060397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021537"(telencephalon development)|go:"GO:0021914"(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|refseq:NP_001020089.1|refseq:NP_081965.2|entrezgene/locuslink:71137(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:8V+H6zUYVwJumq/V+zqYJLQevb410090 rigid:TKMlrqZ1YLuBEEoerjzE6hzgADU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9CPV7 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682495|imex:IM-28774-2199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rigid:82z04/E1i3KE9TCq7NvvjC4lySc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9CYZ8 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682487|imex:IM-28774-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:wly/WK9yohrXX7xsgW3KZHgHFrc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9WV72 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26680645|ensembl:ENSMUSP00000020551|uniprotkb:Q5SSV5 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:asb3_mouse(display_long)|uniprotkb:Asb3(gene name)|psi-mi:Asb3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682479|imex:IM-28774-3051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000020305(gene)|ensembl:ENSMUST00000020551(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037329|refseq:NP_076395.2|refseq:XP_006514834.1|entrezgene/locuslink:65257(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:nZHvNvcF7FjMLl+UCtrdn5ijQQQ10090 rigid:6sHLN0vumuzKRxXsc+ylHZQj83Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8VDQ8 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682471|imex:IM-28774-2639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rigid:JjXANMCCK9plxBs6HEDyWJsTDpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9JHE6 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26679232|ensembl:ENSMUSP00000084062|uniprotkb:Q3U2D7 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:hes6_mouse(display_long)|uniprotkb:Hairy and enhancer of split 6(gene name synonym)|uniprotkb:Hes6(gene name)|psi-mi:Hes6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682463|imex:IM-28774-1741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000067071(gene)|ensembl:ENSMUST00000086851(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_062352.1|entrezgene/locuslink:55927(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:8Rl2iUFTAf9Tc8GEFc1uduxDVXw10090 rigid:XwN5Y2Cyn39nyPlIrxJAlze0wRA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:P70271 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-7288319|intact:MINT-4106929|uniprotkb:Q5SWV2|uniprotkb:Q8K0W4|ensembl:ENSMUSP00000018755 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:pdli4_mouse(display_long)|uniprotkb:Pdlim4(gene name)|psi-mi:Pdlim4(display_short)|uniprotkb:Ril(gene name synonym)|uniprotkb:LIM protein RIL(gene name synonym)|uniprotkb:Reversion-induced LIM protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682455|imex:IM-28774-3049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_062290.2|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0031941"(filamentous actin)|go:"GO:0034777"(recycling endosome lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0043197"(dendritic spine)|ensembl:ENSMUSG00000020388(gene)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061061"(muscle structure development)|go:"GO:0098976"(excitatory chemical synaptic transmission)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|mint:P70271|ensembl:ENSMUST00000018755(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|entrezgene/locuslink:30794(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" comment:mint|comment:homomint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:0p7CYiGd3Vpz5qQL07CNcRse+NQ10090 rigid:kKGyafThpezMv1CgnSU/hjKcSco false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q60769 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-646595|uniprotkb:Q3U968|ensembl:ENSMUSP00000019997|ensembl:ENSMUSP00000101167 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:tnap3_mouse(display_long)|uniprotkb:Putative DNA-binding protein A20(gene name synonym)|uniprotkb:Zinc finger protein A20(gene name synonym)|uniprotkb:Tnfaip3(gene name)|psi-mi:Tnfaip3(display_short)|uniprotkb:Tnfip3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682447|imex:IM-28774-3483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_033423.3|dip:DIP-41120N|refseq:XP_006512765.1|ensembl:ENSMUSG00000019850(gene)|ensembl:ENSMUST00000019997(transcript)|ensembl:ENSMUST00000105527(transcript)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002632"(negative regulation of granuloma formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019900"(kinase binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034148"(negative regulation of toll-like receptor 5 signaling pathway)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070429"(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0072573"(tolerance induction to lipopolysaccharide)|go:"GO:0072666"(establishment of protein localization to vacuole)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1990168"(protein K33-linked deubiquitination)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR033478|mint:Q60769|rcsb pdb:5DQ6|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689896|reactome:R-MMU-936440|entrezgene/locuslink:21929(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:hFNjd3fxx9grjtEq3kAdU0fiFh010090 rigid:gls8riMd7ZoAto+zfr/5j1q7Qbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:O88609 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-13951208|uniprotkb:Q0VEN6 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682439|imex:IM-28774-2197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rigid:LGxxd/Frxyg0pMpMw8AoCjDB0tI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9WUH2 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682431|imex:IM-28774-1739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rigid:5EOodlfv1fL6ameLsRorsg9cH30 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9Z0S2 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26669558|ensembl:ENSMUSP00000000253 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:lhx2_mouse(display_long)|uniprotkb:Lhx2(gene name)|psi-mi:Lhx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682423|imex:IM-28774-1325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021537"(telencephalon development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001942"(hair follicle development)|ensembl:ENSMUSG00000000247(gene)|ensembl:ENSMUST00000000253(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|refseq:NP_034840.1|entrezgene/locuslink:16870(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:i7zOD6AqZ0xIqLJT/dO+vdEeGf410090 rigid:+4W7xyo1CouqwSSnTvLoFlzrWlM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:O55203 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682415|imex:IM-28774-827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:N6pmCarc0xaTyYfpXJixFASEyYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:P70662 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682407|imex:IM-28774-2637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:eTxNPExKxsiuVOljzDlsR5+01gU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:O70220 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26680815|ensembl:ENSMUSP00000036952|uniprotkb:Q9JJ18 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:foxq1_mouse(display_long)|uniprotkb:HFH-1l(gene name synonym)|uniprotkb:HNF-3/forkhead-like protein 1(gene name synonym)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 1(gene name synonym)|uniprotkb:Foxq1(gene name)|psi-mi:Foxq1(display_short)|uniprotkb:Hfh1(gene name synonym)|uniprotkb:Hfh1l(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682399|imex:IM-28774-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000038415(gene)|ensembl:ENSMUST00000042118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_032265.3|entrezgene/locuslink:15220(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:5hw+BoKHYlaFQ3k9Z94TikdHwB410090 rigid:m3PQKJ2o9c5nHt2VnSy8XEOXPMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:P79621 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682391|imex:IM-28774-3481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:IEgGQNSFFFpuqEgrI7E0G/UBbPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VE28 uniprotkb:Q07230 intact:EBI-1538490|uniprotkb:Q3TYU5|uniprotkb:Q3UM34|uniprotkb:Q8C4J8|uniprotkb:Q91Y45|uniprotkb:Q9D7U9|ensembl:ENSMUSP00000022051 intact:EBI-26665895|ensembl:ENSMUSP00000042321 psi-mi:nkd2_mouse(display_long)|uniprotkb:Nkd2(gene name)|psi-mi:Nkd2(display_short) psi-mi:zsca2_mouse(display_long)|uniprotkb:Zinc finger protein 29(gene name synonym)|uniprotkb:Zscan2(gene name)|psi-mi:Zscan2(display_short)|uniprotkb:Zfp-29(gene name synonym)|uniprotkb:Zfp29(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682347|imex:IM-28774-2633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082462.3|refseq:NP_001334464.1|ensembl:ENSMUSG00000021567(gene)|ensembl:ENSMUST00000022051(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140|entrezgene/locuslink:72293(identity) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|rcsb pdb:2I13|ensembl:ENSMUSG00000038797(gene)|ensembl:ENSMUST00000044115(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|refseq:NP_033579.1|refseq:XP_006540868.1|refseq:XP_006540869.1|refseq:XP_006540870.1|refseq:XP_006540871.1|refseq:XP_006540872.1|refseq:XP_006540873.1|refseq:XP_006540874.1|refseq:XP_006540875.1|entrezgene/locuslink:22691(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YahIfIwWuxWNCTmkeFs9nSf8UWc10090 rogid:TKkA1qeOjBvBBvqNNMoIA8zG87w10090 rigid:nCN1l4jL6wmPw/Yx+N5dRbTADr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:P18111 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-21005290|ensembl:ENSMUSP00000025521|uniprotkb:Q8VCF7 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:cdx1_mouse(display_long)|uniprotkb:Caudal-type homeobox protein 1(gene name synonym)|uniprotkb:Cdx1(gene name)|psi-mi:Cdx1(display_short)|uniprotkb:Cdx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682617|imex:IM-28774-1749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) go:"GO:0007389"(pattern specification process)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060349"(bone morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR006820(Caudal-like activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSMUSG00000024619(gene)|ensembl:ENSMUST00000025521(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|refseq:NP_034010.3|entrezgene/locuslink:12590(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:Rzc2qIxNozTifZX/rvuUx8uc6lU10090 rigid:A2KpPGw4QUgAA0Xvy/v3aXIiR9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ESG8 uniprotkb:P31245 intact:EBI-26682584|ensembl:ENSMUSP00000026154|uniprotkb:Q3TI22|uniprotkb:Q3UA59|uniprotkb:Q91XC5 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:zdh16_mouse(display_long)|uniprotkb:Abl-philin 2(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 16(gene name synonym)|uniprotkb:Zdhhc16(gene name)|psi-mi:Zdhhc16(display_short)|uniprotkb:Aph2(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682609|imex:IM-28774-833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025157(gene)|ensembl:ENSMUST00000026154(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007507"(heart development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0021537"(telencephalon development)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR039859|refseq:NP_076229.2|entrezgene/locuslink:74168(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OoHMkPfej5bW2ZM/Zf6vG1kypL810090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:MWHFUDroX6lmNDhEUrCFdGQ5Vt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CF60 uniprotkb:P97334 intact:EBI-16726479|ensembl:ENSMUSP00000023176|uniprotkb:E9PXW0|uniprotkb:Q7TMI6|uniprotkb:Q8K439 intact:EBI-26670620|ensembl:ENSMUSP00000050933|uniprotkb:Q9QZ60|uniprotkb:Q9WV67 psi-mi:zn263_mouse(display_long)|uniprotkb:Znf263(gene name)|psi-mi:Znf263(display_short)|uniprotkb:FPM315(gene name synonym)|uniprotkb:ZKSCAN12(gene name synonym)|uniprotkb:Zfp263(gene name synonym)|uniprotkb:Zinc finger protein FPM315(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 12(gene name synonym) psi-mi:nkx23_mouse(display_long)|uniprotkb:Homeobox protein NK-2 homolog 3(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog C(gene name synonym)|uniprotkb:Nkx2-C(gene name synonym)|uniprotkb:Nkx2-3(gene name)|psi-mi:Nkx2-3(display_short)|uniprotkb:Nkx-2.3(gene name synonym)|uniprotkb:Nkx2c(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682576|imex:IM-28774-1747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022529(gene)|ensembl:ENSMUST00000023176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030752|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_683726.2|entrezgene/locuslink:74120(identity) ensembl:ENSMUSG00000044220(gene)|ensembl:ENSMUST00000057178(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048565"(digestive tract development)|go:"GO:0048621"(post-embryonic digestive tract morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0022612"(gland morphogenesis)|refseq:NP_032725.1|entrezgene/locuslink:18089(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:psPERDxBYR4ymhFeKtm03GkxOzg10090 rogid:bLGV6jFbwIJSrV3mhxasbc8RPBc10090 rigid:+Sbdz/6/Vyi3ZM8mrUVm1S+kCGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8CF60 uniprotkb:P70436 intact:EBI-16726479|ensembl:ENSMUSP00000023176|uniprotkb:E9PXW0|uniprotkb:Q7TMI6|uniprotkb:Q8K439 intact:EBI-1801333|uniprotkb:Q3UM51|uniprotkb:Q8R4I3|ensembl:ENSMUSP00000021241 psi-mi:zn263_mouse(display_long)|uniprotkb:Znf263(gene name)|psi-mi:Znf263(display_short)|uniprotkb:FPM315(gene name synonym)|uniprotkb:ZKSCAN12(gene name synonym)|uniprotkb:Zfp263(gene name synonym)|uniprotkb:Zinc finger protein FPM315(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 12(gene name synonym) psi-mi:dlx4_mouse(display_long)|uniprotkb:Dlx4(gene name)|psi-mi:Dlx4(display_short)|uniprotkb:Dlx7(gene name synonym)|uniprotkb:Homeobox protein DLX-7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682568|imex:IM-28774-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022529(gene)|ensembl:ENSMUST00000023176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030752|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-MMU-212436|refseq:NP_683726.2|entrezgene/locuslink:74120(identity) refseq:NP_031893.3|ensembl:ENSMUSG00000020871(gene)|ensembl:ENSMUST00000021241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:13394(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:psPERDxBYR4ymhFeKtm03GkxOzg10090 rogid:qdYVFVDe+39K0nv/Gz2X5WexmHg10090 rigid:GkSgB79ijizSptB9wuiAhKNKnbI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55055 uniprotkb:P19793 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682528|imex:IM-28774-1745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N|entrezgene/locuslink:7376(identity) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|entrezgene/locuslink:6256(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rigid:DX/Gxbnrq2hnyOIlkP3GH09AxIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55055 uniprotkb:P48443 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682552|imex:IM-28774-3055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N|entrezgene/locuslink:7376(identity) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rigid:uzUOTo0pRlWvWp9OFrTx2s0jbfw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55055 uniprotkb:P28702 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682544|imex:IM-28774-831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N|entrezgene/locuslink:7376(identity) refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|entrezgene/locuslink:6257(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:63pJ6HNyL3L1nqpwdCgIkmdAO3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55055 uniprotkb:P19793 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682536|imex:IM-28774-829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N|entrezgene/locuslink:7376(identity) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|entrezgene/locuslink:6256(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rigid:DX/Gxbnrq2hnyOIlkP3GH09AxIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55055 uniprotkb:P48443 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682560|imex:IM-28774-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N|entrezgene/locuslink:7376(identity) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rigid:uzUOTo0pRlWvWp9OFrTx2s0jbfw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPZ6 uniprotkb:O55144 intact:EBI-26682960 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:tbx18_mouse(display_long)|uniprotkb:Tbx18(gene name)|psi-mi:Tbx18(display_short) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682998|imex:IM-28774-1765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003163"(sinoatrial node development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0060829"(negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation)|go:"GO:0060930"(sinoatrial node cell fate commitment)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072189"(ureter development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000729"(positive regulation of mesenchymal cell proliferation involved in ureter development)|refseq:NP_076303.3|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR036960|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR018186|entrezgene/locuslink:76365(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ocGIFnI99s9E5iqH8V5eE8dcBdo10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:7ZYIh9bjGvgx2sB2KvatrdA48uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q8VCD7 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-11580493|uniprotkb:Q3UNP7|uniprotkb:Q69ZZ5|uniprotkb:Q8BUY6|uniprotkb:Q8BWA1|ensembl:ENSMUSP00000030102|ensembl:ENSMUSP00000077017 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:kdm4c_mouse(display_long)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:Kdm4c(gene name)|psi-mi:Kdm4c(display_short)|uniprotkb:Jhdm3c(gene name synonym)|uniprotkb:Jmjd2c(gene name synonym)|uniprotkb:Kiaa0780(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683006|imex:IM-28774-3495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_001165566.1|refseq:NP_659036.1|refseq:XP_006538415.1|ensembl:ENSMUST00000077851(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|reactome:R-MMU-3214842|reactome:R-MMU-5625886|ensembl:ENSMUSG00000028397(gene)|ensembl:ENSMUST00000030102(transcript)|entrezgene/locuslink:76804(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:tFdMzJVdBk+JwOhSmol2i85MLJI10090 rigid:hRpqsjxkCBJe/eVYE+QxA5J5ieE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24278 uniprotkb:P61457 intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682936|imex:IM-28774-1763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:2HLv5mVwjmytvOnp9XlqeRGuNec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24278 uniprotkb:P14317 intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746 intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176 psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym) psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682928|imex:IM-28774-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity) ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606 rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606 rigid:Q7vJiAbE20W5w/5I1dNS78BZRLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13682 uniprotkb:Q99459 intact:EBI-11041653|uniprotkb:Q96D01|uniprotkb:Q53Y54|uniprotkb:B2RBU6|ensembl:ENSP00000379368|ensembl:ENSP00000486354 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 psi-mi:znf35_human(display_long)|uniprotkb:ZNF35(gene name)|psi-mi:ZNF35(display_short)|uniprotkb:Zinc finger protein HF.10(gene name synonym) psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682920|imex:IM-28774-1761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003411.3|ensembl:ENSG00000169981(gene)|ensembl:ENSG00000281306(gene)|ensembl:ENST00000396056(transcript)|ensembl:ENST00000625394(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_016862618.1|refseq:XP_016862619.1|refseq:XP_016862620.1|entrezgene/locuslink:7584(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|entrezgene/locuslink:988(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Qs+B3EB5t18vwnkjGDODPsP2IVg9606 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 rigid:ylRKlFnsz33O0uYH8CVUwUXMPT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13682 uniprotkb:P16220 intact:EBI-11041653|uniprotkb:Q96D01|uniprotkb:Q53Y54|uniprotkb:B2RBU6|ensembl:ENSP00000379368|ensembl:ENSP00000486354 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:znf35_human(display_long)|uniprotkb:ZNF35(gene name)|psi-mi:ZNF35(display_short)|uniprotkb:Zinc finger protein HF.10(gene name synonym) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682912|imex:IM-28774-3493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003411.3|ensembl:ENSG00000169981(gene)|ensembl:ENSG00000281306(gene)|ensembl:ENST00000396056(transcript)|ensembl:ENST00000625394(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:XP_016862618.1|refseq:XP_016862619.1|refseq:XP_016862620.1|entrezgene/locuslink:7584(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Qs+B3EB5t18vwnkjGDODPsP2IVg9606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:NL68V29yjCiCcYtGr5Lc/hW6g1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17027 uniprotkb:P61457 intact:EBI-5657766|uniprotkb:Q8NDP5|uniprotkb:Q96IT3|uniprotkb:Q9UG42|ensembl:ENSP00000349796|ensembl:ENSP00000377171|ensembl:ENSP00000387673 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:znf23_human(display_long)|uniprotkb:KOX16(gene name synonym)|uniprotkb:ZNF359(gene name synonym)|uniprotkb:ZNF612(gene name synonym)|uniprotkb:Zinc finger protein 359(gene name synonym)|uniprotkb:Zinc finger protein 612(gene name synonym)|uniprotkb:Zinc finger protein KOX16(gene name synonym)|uniprotkb:ZNF23(gene name)|psi-mi:ZNF23(display_short) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682904|imex:IM-28774-1759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001291421.1|refseq:NP_001291422.1|refseq:NP_001291423.1|refseq:NP_666016.1|ensembl:ENSG00000167377(gene)|ensembl:ENST00000357254(transcript)|ensembl:ENST00000393539(transcript)|ensembl:ENST00000428724(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P17027|reactome:R-HSA-212436|entrezgene/locuslink:7571(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:N5hIISReQVVo0kOTNVvoUS59+fk9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:Z1xEedW1bjRQclksPr4p54VTNlo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D032 uniprotkb:Q9EP71 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682896|imex:IM-28774-3491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71|entrezgene/locuslink:75646(identity) - comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 rigid:4drAoB45JRcoL7U86OSkfwOmohQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EP71 uniprotkb:Q9WUL8 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682888|imex:IM-28774-3489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71|entrezgene/locuslink:75646(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:hfLyAx6CRsQKb7PW2sz5wvrdOto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EP71 uniprotkb:P15806 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682880|imex:IM-28774-845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71|entrezgene/locuslink:75646(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:fFgqYZ1RrWLr50jGdrycDQ+Vhbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EP71 uniprotkb:P31245 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682872|imex:IM-28774-1757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71|entrezgene/locuslink:75646(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:lI8XHbyiaERecRSFZOaM25bBBS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EP71 uniprotkb:Q61545 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682864|imex:IM-28774-1331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71|entrezgene/locuslink:75646(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:gcj7lheG6m+mtD6rVgarJ14FtWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26651 uniprotkb:P31274 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682856|imex:IM-28774-2647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N|entrezgene/locuslink:7538(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:qxwoMpIJA/6EaAL74K2L5ZmTn7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91X45 uniprotkb:Q8VDQ8 intact:EBI-26682795|ensembl:ENSMUSP00000127746|uniprotkb:Q3UQP3|uniprotkb:Q8BIJ4 intact:EBI-911012|uniprotkb:Q9CXS5|uniprotkb:Q9EQ18|uniprotkb:Q9ERJ9|uniprotkb:E9PXF5|uniprotkb:U5TP50|ensembl:ENSMUSP00000072732 psi-mi:zbtb3_mouse(display_long)|uniprotkb:Zbtb3(gene name)|psi-mi:Zbtb3(display_short) psi-mi:sir2_mouse(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682848|imex:IM-28774-843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071661(gene)|ensembl:ENSMUST00000172175(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001091707.1|refseq:NP_598520.1|refseq:XP_006527482.1|entrezgene/locuslink:75291(identity) refseq:NP_001116237.1|refseq:NP_001116238.1|refseq:NP_071877.3|ensembl:ENSMUSG00000015149(gene)|ensembl:ENSMUST00000072965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8VDQ8|reactome:R-MMU-2995383|entrezgene/locuslink:64383(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d2o0F75J5RWiKxWofBPvTEkuCcE10090 rogid:dyZrcj6ZdRM0ec1bEqdoqsOTIgg10090 rigid:G8qLrOK5qqye7QC8akwhqFAdoyk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91X45 uniprotkb:Q9CZT4 intact:EBI-26682795|ensembl:ENSMUSP00000127746|uniprotkb:Q3UQP3|uniprotkb:Q8BIJ4 intact:EBI-26677825|ensembl:ENSMUSP00000033173|ensembl:ENSMUSP00000102092|uniprotkb:Q8CI35|uniprotkb:Q9DBD1 psi-mi:zbtb3_mouse(display_long)|uniprotkb:Zbtb3(gene name)|psi-mi:Zbtb3(display_short) psi-mi:rpc5_mouse(display_long)|uniprotkb:Sex-lethal interactor homolog(gene name synonym)|uniprotkb:Polr3e(gene name)|psi-mi:Polr3e(display_short)|uniprotkb:Sin(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682840|imex:IM-28774-1329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071661(gene)|ensembl:ENSMUST00000172175(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001091707.1|refseq:NP_598520.1|refseq:XP_006527482.1|entrezgene/locuslink:75291(identity) ensembl:ENSMUSG00000030880(gene)|ensembl:ENSMUST00000033173(transcript)|ensembl:ENSMUST00000106483(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR006886(Sin-like protein conserved region)|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|refseq:NP_001157568.1|refseq:NP_079574.2|entrezgene/locuslink:26939(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d2o0F75J5RWiKxWofBPvTEkuCcE10090 rogid:0JD6k+Kwr+i6mwVzjlATHbG2HM810090 rigid:JppCCcETor7x3aafp/Os8H8Nclc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91X45 uniprotkb:Q811S7 intact:EBI-26682795|ensembl:ENSMUSP00000127746|uniprotkb:Q3UQP3|uniprotkb:Q8BIJ4 intact:EBI-5710174|uniprotkb:A4QPG4|uniprotkb:Q3UPR3|uniprotkb:Q3US11|uniprotkb:Q60786|uniprotkb:Q8C514|ensembl:ENSMUSP00000081946|ensembl:ENSMUSP00000150023 psi-mi:zbtb3_mouse(display_long)|uniprotkb:Zbtb3(gene name)|psi-mi:Zbtb3(display_short) psi-mi:ubip1_mouse(display_long)|uniprotkb:Ubp1(gene name)|psi-mi:Ubp1(display_short)|uniprotkb:Cp2b(gene name synonym)|uniprotkb:Nf2d9(gene name synonym)|uniprotkb:Nuclear factor 2d9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682832|imex:IM-28774-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071661(gene)|ensembl:ENSMUST00000172175(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001091707.1|refseq:NP_598520.1|refseq:XP_006527482.1|entrezgene/locuslink:75291(identity) refseq:NP_001076788.1|refseq:NP_038727.1|refseq:XP_006512114.2|refseq:XP_006512117.2|ensembl:ENSMUSG00000009741(gene)|ensembl:ENSMUST00000084885(transcript)|ensembl:ENSMUST00000216558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037600|interpro:IPR041418|mint:Q811S7|entrezgene/locuslink:22221(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d2o0F75J5RWiKxWofBPvTEkuCcE10090 rogid:Nt11E5Wv/MovMgjsl1GUvjXxz8Y10090 rigid:oW/rh3YHTsibIy/PgkD1JkSdAdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91X45 uniprotkb:Q8R0B5 intact:EBI-26682795|ensembl:ENSMUSP00000127746|uniprotkb:Q3UQP3|uniprotkb:Q8BIJ4 intact:EBI-26670824|ensembl:ENSMUSP00000112532 psi-mi:zbtb3_mouse(display_long)|uniprotkb:Zbtb3(gene name)|psi-mi:Zbtb3(display_short) psi-mi:q8r0b5_mouse(display_long)|uniprotkb:Otx2(gene name)|psi-mi:Otx2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682824|imex:IM-28774-841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071661(gene)|ensembl:ENSMUST00000172175(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001091707.1|refseq:NP_598520.1|refseq:XP_006527482.1|entrezgene/locuslink:75291(identity) ensembl:ENSMUSG00000021848(gene)|ensembl:ENSMUST00000119070(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0030426"(growth cone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR003022(Transcription factor Otx2)|interpro:IPR003025(Transcription factor Otx)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|refseq:NP_001273410.1|refseq:XP_011243290.1|refseq:XP_017171402.1|refseq:XP_017171403.1|refseq:XP_017171404.1|refseq:XP_017171405.1|entrezgene/locuslink:18424(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:d2o0F75J5RWiKxWofBPvTEkuCcE10090 rogid:qKlhFtipAkQaTNnkfkJ8eJCQACY10090 rigid:I+81pfcjyhMH7Jnd2NLSVQF7Ycg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54826 uniprotkb:Q91X45 intact:EBI-8459555|uniprotkb:Q6NS43|intact:MINT-4087317|ensembl:ENSMUSP00000028076|ensembl:ENSMUSP00000110328 intact:EBI-26682795|ensembl:ENSMUSP00000127746|uniprotkb:Q3UQP3|uniprotkb:Q8BIJ4 psi-mi:af10_mouse(display_long)|uniprotkb:Mllt10(gene name)|psi-mi:Mllt10(display_short)|uniprotkb:Af10(gene name synonym) psi-mi:zbtb3_mouse(display_long)|uniprotkb:Zbtb3(gene name)|psi-mi:Zbtb3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682816|imex:IM-28774-2645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001239489.1|refseq:NP_034934.2|refseq:XP_006497440.2|dip:DIP-58954N|ensembl:ENSMUSG00000026743(gene)|ensembl:ENSMUST00000028076(transcript)|ensembl:ENSMUST00000114680(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O54826|entrezgene/locuslink:17354(identity) ensembl:ENSMUSG00000071661(gene)|ensembl:ENSMUST00000172175(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001091707.1|refseq:NP_598520.1|refseq:XP_006527482.1|entrezgene/locuslink:75291(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:GtuZGrk+mN3Rrx1+4h10iHG05Us10090 rogid:d2o0F75J5RWiKxWofBPvTEkuCcE10090 rigid:WhZHRJaw4qETSzsimoQ+yR4BKug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D504 uniprotkb:Q04207 intact:EBI-26682761|ensembl:ENSMUSP00000031489|uniprotkb:Q810N2|uniprotkb:Q8BVP4 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:ankr7_mouse(display_long)|uniprotkb:Ankrd7(gene name)|psi-mi:Ankrd7(display_short) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682787|imex:IM-28774-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029517(gene)|ensembl:ENSMUST00000031489(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001161229.1|refseq:NP_083478.2|entrezgene/locuslink:75196(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Umj6z9xHiWYccNguta8eM00/ro410090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:+JHtK5bKbMpD0a99lzoPs5/Zbz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D504 uniprotkb:Q61545 intact:EBI-26682761|ensembl:ENSMUSP00000031489|uniprotkb:Q810N2|uniprotkb:Q8BVP4 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:ankr7_mouse(display_long)|uniprotkb:Ankrd7(gene name)|psi-mi:Ankrd7(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682779|imex:IM-28774-839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029517(gene)|ensembl:ENSMUST00000031489(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001161229.1|refseq:NP_083478.2|entrezgene/locuslink:75196(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Umj6z9xHiWYccNguta8eM00/ro410090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:R4BFUBMotYCSihng1Wjft7YOwMk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:O60224 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-745513|uniprotkb:Q5JQZ0|uniprotkb:Q9UJU9|uniprotkb:B2RPE3|ensembl:ENSP00000469011|ensembl:ENSP00000469394|uniprotkb:A8MYD4|uniprotkb:Q3SYD4 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:ssx4_human(display_long)|uniprotkb:Cancer/testis antigen 5.4(gene name synonym)|uniprotkb:SSX4(gene name)|psi-mi:SSX4(display_short)|uniprotkb:SSX4B(gene name)|psi-mi:SSX4B(display_short)|uniprotkb:SSX4A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682753|imex:IM-28774-1755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_001030004.1|refseq:NP_005627.1|refseq:NP_783856.1|ensembl:ENSG00000268009(gene)|ensembl:ENSG00000269791(gene)|ensembl:ENST00000595235(transcript)|ensembl:ENST00000595689(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|refseq:NP_001035702.1|refseq:XP_016885102.1|refseq:XP_016885248.1|entrezgene/locuslink:6759(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:XHHJJoIvvSIjm/AO1gB1lYvXlHE9606 rigid:ABsniRm6lVjctxYW4ZrrWYExO5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q07955 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682745|imex:IM-28774-2207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A|entrezgene/locuslink:6426(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:sP97Lmns8zbnGqeK/Kz+BvJ1Kws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q08999 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-971439|ensembl:ENSP00000262133|uniprotkb:Q15073|uniprotkb:Q16084|uniprotkb:Q92812|uniprotkb:B7Z913|uniprotkb:Q8NE70 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:rbl2_human(display_long)|uniprotkb:RBL2(gene name)|psi-mi:RBL2(display_short)|uniprotkb:RB2(gene name synonym)|uniprotkb:Retinoblastoma-related protein 2(gene name synonym)|uniprotkb:130 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:pRb2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682737|imex:IM-28774-837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) ensembl:ENSG00000103479(gene)|ensembl:ENST00000262133(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028308|interpro:IPR028309|interpro:IPR036915|mint:Q08999|rcsb pdb:4XI9|rcsb pdb:5C1D|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-9617828|refseq:NP_005602.3|refseq:NP_001310537.1|dip:DIP-425N|entrezgene/locuslink:5934(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:2/u/ejPv7UkPWeZYyfJpZXf9Roc9606 rigid:GDpiEjDDVUuyJ1AZh11ndwfIxDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:P51858 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-3910118|uniprotkb:Q5SZ09|uniprotkb:D3DVC9|uniprotkb:Q5SZ07|uniprotkb:B3KU21|uniprotkb:Q5SZ08|ensembl:ENSP00000349878|ensembl:ENSP00000443120 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:hdgf_human(display_long)|uniprotkb:HDGF(gene name)|psi-mi:HDGF(display_short)|uniprotkb:HMG1L2(gene name synonym)|uniprotkb:High mobility group protein 1-like 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682729|imex:IM-28774-2205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_001119522.1|refseq:NP_001119523.1|refseq:NP_004485.1|refseq:NP_001306115.1|refseq:NP_001306116.1|refseq:NP_001306117.1|ensembl:ENSG00000143321(gene)|ensembl:ENST00000357325(transcript)|ensembl:ENST00000537739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000313(PWWP)|interpro:IPR035496|mint:P51858|rcsb pdb:1RI0|rcsb pdb:2NLU|reactome:R-HSA-381038|entrezgene/locuslink:3068(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:72uY+spcb4la5tJDUhHHtOn/Zrs9606 rigid:Ky95/zNbnWjxbUM3E1oTBH0+Ugg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:P07305 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682721|imex:IM-28774-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N|entrezgene/locuslink:3005(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606 rigid:aJ02mnu7gimdS1+wGBjVjCo2/jE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:P08151 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682713|imex:IM-28774-2203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N|entrezgene/locuslink:2735(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 rigid:4U03BP5Lr87+iM6TikotyIq6suw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G3X8Y3 uniprotkb:Q61545 intact:EBI-11027950|ensembl:ENSMUSP00000029303 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:g3x8y3_mouse(display_long)|uniprotkb:Naa15(gene name)|psi-mi:Naa15(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682705|imex:IM-28774-3059 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444319.3|ensembl:ENSMUSG00000063273(gene)|ensembl:ENSMUST00000029303(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|entrezgene/locuslink:74838(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Qmtk8YBGa66vFWkMV3xr1vzD+Iw10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:Gb3LHj1UgcGHEqk8VxMERssSN6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9CWW7 uniprotkb:Q04207 intact:EBI-11057018|ensembl:ENSMUSP00000025444 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:cxxc1_mouse(display_long)|uniprotkb:Cxxc1(gene name)|psi-mi:Cxxc1(display_short)|uniprotkb:Cgbp(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:Pccx1(gene name synonym) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682697|imex:IM-28774-2643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083144.1|ensembl:ENSMUSG00000024560(gene)|ensembl:ENSMUST00000025444(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR022056|interpro:IPR037869|entrezgene/locuslink:74322(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:F8l4yKXUMeRz4IzsTFgLRlA3I7E10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:bl7yShJaxP/iHsvUENMrih5zsKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11473 uniprotkb:P48443 intact:EBI-286357|uniprotkb:Q5PSV3|uniprotkb:B2R5Q1|uniprotkb:G3V1V9|ensembl:ENSP00000378734|ensembl:ENSP00000449573 intact:EBI-712405|uniprotkb:A6NIP1|uniprotkb:Q6IBU7|ensembl:ENSP00000352900 psi-mi:vdr_human(display_long)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym)|uniprotkb:VDR(gene name)|psi-mi:VDR(display_short)|uniprotkb:NR1I1(gene name synonym) psi-mi:rxrg_human(display_long)|uniprotkb:Retinoid X receptor gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 3(gene name synonym)|uniprotkb:RXRG(gene name)|psi-mi:RXRG(display_short)|uniprotkb:NR2B3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682689|imex:IM-28774-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000367.1|refseq:NP_001017535.1|refseq:NP_001017536.1|refseq:XP_006719650.1|refseq:XP_011537022.1|dip:DIP-32624N|ensembl:ENSG00000111424(gene)|ensembl:ENST00000395324(transcript)|ensembl:ENST00000549336(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P11473|rcsb pdb:1DB1|rcsb pdb:1IE8|rcsb pdb:1IE9|rcsb pdb:1KB2|rcsb pdb:1KB4|rcsb pdb:1KB6|rcsb pdb:1S0Z|rcsb pdb:1S19|rcsb pdb:1TXI|rcsb pdb:1YNW|rcsb pdb:2HAM|rcsb pdb:2HAR|rcsb pdb:2HAS|rcsb pdb:2HB7|rcsb pdb:2HB8|rcsb pdb:3A2I|rcsb pdb:3A2J|rcsb pdb:3A3Z|rcsb pdb:3A40|rcsb pdb:3A78|rcsb pdb:3AUQ|rcsb pdb:3AUR|rcsb pdb:3AX8|rcsb pdb:3AZ1|rcsb pdb:3AZ2|rcsb pdb:3AZ3|rcsb pdb:3B0T|rcsb pdb:3CS4|rcsb pdb:3CS6|rcsb pdb:3KPZ|rcsb pdb:3M7R|rcsb pdb:3OGT|rcsb pdb:3P8X|rcsb pdb:3TKC|rcsb pdb:3VHW|rcsb pdb:3W0A|rcsb pdb:3W0C|rcsb pdb:3W0Y|rcsb pdb:3WGP|rcsb pdb:3WWR|rcsb pdb:3X31|rcsb pdb:3X36|rcsb pdb:4G2I|rcsb pdb:4ITE|rcsb pdb:4ITF|rcsb pdb:5GT4|rcsb pdb:5V39|rcsb pdb:5YSY|rcsb pdb:5YT2|reactome:R-HSA-196791|reactome:R-HSA-383280|reactome:R-HSA-4090294|entrezgene/locuslink:7421(identity) ensembl:ENSG00000143171(gene)|ensembl:ENST00000359842(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P48443|rcsb pdb:2GL8|reactome:R-HSA-383280|reactome:R-HSA-5362517|rcsb pdb:7A79|refseq:NP_008848.1|refseq:NP_001243500.1|dip:DIP-56220N|entrezgene/locuslink:6258(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7j3KKs/nPSWIKLnb2SZqA+UAysM9606 rogid:JyDC15QTaxG7uPzgOPnh8fP+2no9606 rigid:yh0ypKavEel3oO0CofeKSRGOG9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q9DAI4 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-3043997|ensembl:ENSMUSP00000028125 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:zbt43_mouse(display_long)|uniprotkb:Zbtb43(gene name)|psi-mi:Zbtb43(display_short)|uniprotkb:Kiaa0414(gene name synonym)|uniprotkb:Zfp297b(gene name synonym)|uniprotkb:Znf297b(gene name synonym)|uniprotkb:Zinc finger protein 297B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682681|imex:IM-28774-1753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) ensembl:ENSMUSG00000026788(gene)|ensembl:ENSMUST00000028125(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001020765.1|refseq:NP_082223.2|refseq:XP_006498411.1|refseq:XP_006498412.1|entrezgene/locuslink:71834(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:030jfmiLnu9yNDqjpY1VFYE1qRk10090 rigid:ht85p20DGD81AiIvN84lxKil91U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q9D902 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682673|imex:IM-28774-1751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rigid:tblSdjshsdWVNE/FU/xaauqEUcA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q9D902 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-309435|uniprotkb:Q3U5Y7|uniprotkb:Q8BTZ2|uniprotkb:Q8VE14|ensembl:ENSMUSP00000126284|ensembl:ENSMUSP00000129834|ensembl:ENSMUSP00000132287 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:t2eb_mouse(display_long)|uniprotkb:Gtf2e2(gene name)|psi-mi:Gtf2e2(display_short)|uniprotkb:Transcription initiation factor IIE subunit beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682665|imex:IM-28774-2201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) dip:DIP-49546N|refseq:NP_001161393.1|refseq:NP_001161394.1|refseq:NP_080860.3|refseq:XP_006509249.1|refseq:XP_006509250.1|refseq:XP_006509251.1|ensembl:ENSMUSG00000031585(gene)|ensembl:ENSMUST00000167264(transcript)|ensembl:ENSMUST00000170705(transcript)|ensembl:ENSMUST00000171010(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:Q9D902|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:68153(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:EODfoQNfoUeYFU67UZPql9HzCB410090 rigid:tblSdjshsdWVNE/FU/xaauqEUcA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q9JKN5 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-1213712|ensembl:ENSMUSP00000061408 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:olig1_mouse(display_long)|uniprotkb:Olig1(gene name)|psi-mi:Olig1(display_short)|uniprotkb:Oligodendrocyte-specific bHLH transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682657|imex:IM-28774-835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) refseq:NP_058664.2|ensembl:ENSMUSG00000046160(gene)|ensembl:ENSMUST00000056882(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q9JKN5|entrezgene/locuslink:50914(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:1R93ekMg/uZq5unF9PJGlf/iiJ810090 rigid:umEyZOEydYj/0MTIG5IMpWoIeBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q9WUI0 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-13637214|ensembl:ENSMUSP00000027778|uniprotkb:Q9QZ61 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:mixl1_mouse(display_long)|uniprotkb:Homeodomain protein MIX(gene name synonym)|uniprotkb:MIX1 homeobox-like protein 1(gene name synonym)|uniprotkb:Mix.1 homeobox-like protein(gene name synonym)|uniprotkb:Mixl1(gene name)|psi-mi:Mixl1(display_short)|uniprotkb:Mix(gene name synonym)|uniprotkb:Mml(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682649|imex:IM-28774-3057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) ensembl:ENSMUSG00000026497(gene)|ensembl:ENSMUST00000027778(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001706"(endoderm formation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042917|go:"GO:2000382"(positive regulation of mesoderm development)|refseq:NP_038757.1|refseq:XP_006496934.1|entrezgene/locuslink:27217(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:pI6ood5ZYYkD/PilkNv8nV9DbBs10090 rigid:XV247AQsmZt9cEd2cthtefYBBCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q60953 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-3895605|uniprotkb:Q8CEJ1|uniprotkb:Q8VCC4|ensembl:ENSMUSP00000082816 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:pml_mouse(display_long)|uniprotkb:Pml(gene name)|psi-mi:Pml(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682641|imex:IM-28774-3487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) refseq:NP_032910.3|refseq:NP_835188.2|dip:DIP-29279N|refseq:NP_001298017.1|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR021978|mint:Q60953|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-6804758|reactome:R-MMU-8934593|reactome:R-MMU-8948747|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|ensembl:ENSMUSG00000036986(gene)|ensembl:ENSMUST00000085673(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|entrezgene/locuslink:18854(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:A1IYoBcjvvc01u8zfXWPo7ANLSo10090 rigid:4RGQG0UOftaMFt0WNEez5V7QDn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q07279 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682633|imex:IM-28774-1327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:e/SICM5W/K5CfSSUwkR8xh2r4H8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D0D5 uniprotkb:Q05BA5 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682625|imex:IM-28774-2641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:74197(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:nbp7mnOoXS7QKrZAT5QG68HCh1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P97769 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26683022|ensembl:ENSMUSP00000051789|ensembl:ENSMUSP00000098890 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:cite1_mouse(display_long)|uniprotkb:Melanocyte-specific protein 1(gene name synonym)|uniprotkb:Cited1(gene name)|psi-mi:Cited1(display_short)|uniprotkb:Msg1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683084|imex:IM-28774-3061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000051159(gene)|ensembl:ENSMUST00000050551(transcript)|ensembl:ENSMUST00000101336(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001890"(placenta development)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032868"(response to insulin)|go:"GO:0034097"(response to cytokine)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043473"(pigmentation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070669"(response to interleukin-2)|go:"GO:0070670"(response to interleukin-4)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071104"(response to interleukin-9)|go:"GO:0071105"(response to interleukin-11)|go:"GO:0071107"(response to parathyroid hormone)|go:"GO:0071559"(response to transforming growth factor beta)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|reactome:R-MMU-9018519|refseq:NP_001263395.1|refseq:NP_001263402.1|refseq:NP_001263403.1|refseq:NP_031735.1|entrezgene/locuslink:12705(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:V9x2gtKnL1lGUTiNAeWT74TMyhk10090 rigid:1v076f3FNfrw7J+5cRMyItBHmH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q00322 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-15611593|ensembl:ENSMUSP00000148145|uniprotkb:Q3U937|uniprotkb:Q8BW92 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:cebpd_mouse(display_long)|uniprotkb:C/EBP-related protein 3(gene name synonym)|uniprotkb:Cebpd(gene name)|psi-mi:Cebpd(display_short)|uniprotkb:Crp3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683014|imex:IM-28774-847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000071637(gene)|ensembl:ENSMUST00000096232(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|refseq:NP_031705.3|dip:DIP-41645N|entrezgene/locuslink:12609(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:aCmCPifzzDnsat5YKja5onlnM6E10090 rigid:IDFmsUBvvvY/5FCv8V0RdosYxy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24278 uniprotkb:P24278 intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746 intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746 psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym) psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682944|imex:IM-28774-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity) refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606 rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606 rigid:/M75J5l6OdLRKyIqw9+bCqylk00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:Q9WUQ2 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-2553903|uniprotkb:Q9QZ99|ensembl:ENSMUSP00000074387 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:preb_mouse(display_long)|uniprotkb:Sec12(gene name synonym)|uniprotkb:Mammalian guanine nucleotide exchange factor mSec12(gene name synonym)|uniprotkb:Preb(gene name)|psi-mi:Preb(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683421|imex:IM-28774-2653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) refseq:NP_057912.2|ensembl:ENSMUSG00000045302(gene)|ensembl:ENSMUST00000074840(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0009306"(protein secretion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051020"(GTPase binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|mint:Q9WUQ2|reactome:R-MMU-204005|reactome:R-MMU-5694530|entrezgene/locuslink:50907(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:jqksMFrLiRmK02t/KLC4ng11UGU10090 rigid:IjuE94YaFVSzDGhgxwMvxHHNrFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:F8VPR5 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-10989694|ensembl:ENSMUSP00000023165 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:f8vpr5_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683092|imex:IM-28774-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_001020603.1|ensembl:ENSMUSG00000022521(gene)|ensembl:ENSMUST00000023165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|go:"GO:0005737"(cytoplasm)|entrezgene/locuslink:12914(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:9K1igrA8QbILB/vG1/XLKh9kzJM10090 rigid:QZt6u89qgWn1EJxa8krwmaJer38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:A4QPD3 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-26676726|ensembl:ENSMUSP00000099928 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:a4qpd3_mouse(display_long)|uniprotkb:Rel(gene name)|psi-mi:Rel(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683405|imex:IM-28774-1773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) ensembl:ENSMUSG00000020275(gene)|ensembl:ENSMUST00000102864(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030505|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|interpro:IPR042845|refseq:NP_033070.2|entrezgene/locuslink:19696(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:+ZOsI/t9cx8uPhk6I1RZy7AyBRc10090 rigid:HqinsIXy4w97ZaPpaY9eYiHmKYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:O88609 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-13951208|uniprotkb:Q0VEN6 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:lmx1b_mouse(display_long)|uniprotkb:Lmx1b(gene name)|psi-mi:Lmx1b(display_short)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683397|imex:IM-28774-3067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0021587"(cerebellum morphogenesis)|refseq:NP_034855.2|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035265"(organ growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050808"(synapse organization)|go:"GO:0071542"(dopaminergic neuron differentiation)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|entrezgene/locuslink:16917(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:cuCwa39MvAWc7sWkxjHWeNZSKns10090 rigid:Ru7ISmtdF0SSWzV0XKl5VR7ztNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:Q9WUH2 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-309943|uniprotkb:Q9QYQ5|uniprotkb:Q9QYQ6|uniprotkb:Q9QZ00|uniprotkb:Q9WU44|uniprotkb:Q6GQU4|ensembl:ENSMUSP00000107657 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:lhx9_mouse(display_long)|uniprotkb:Lhx9(gene name)|psi-mi:Lhx9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683389|imex:IM-28774-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) refseq:NP_001020736.1|refseq:NP_001036042.1|refseq:NP_034844.1|refseq:XP_006529234.1|refseq:XP_006529235.1|refseq:XP_006529236.1|ensembl:ENSMUSG00000019230(gene)|ensembl:ENSMUST00000112026(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097380"(dorsal spinal cord interneuron anterior axon guidance)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR017970|refseq:XP_017174117.1|refseq:XP_017174126.1|entrezgene/locuslink:16876(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:s4c7v6ly14ws4h5AZTQnly7AGgc10090 rigid:CvtQTihq8fmCTqsLQ0Rj2lqrU6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:O55203 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-15657830|ensembl:ENSMUSP00000067737|uniprotkb:O55205|uniprotkb:Q3UHY1|uniprotkb:Q6AXE6 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:ldb2_mouse(display_long)|uniprotkb:Ldb2(gene name)|psi-mi:Ldb2(display_short)|uniprotkb:Clim1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683381|imex:IM-28774-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) ensembl:ENSMUSG00000039706(gene)|ensembl:ENSMUST00000070748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|refseq:NP_001070866.1|refseq:NP_001273277.1|refseq:NP_034828.3|refseq:XP_006503817.1|refseq:XP_006503819.1|dip:DIP-46444N|entrezgene/locuslink:16826(identity) - - "mimix:comment":not sure if in every case the origin is the same figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:BGyRj6BxhHIZzkK7TNBi769iu4U10090 rigid:0MC9mmamZMXX7M46ClwaD1E6NPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:P70662 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-6272082|ensembl:ENSMUSP00000118546|ensembl:ENSMUSP00000139562|uniprotkb:O55204|uniprotkb:Q1EQX2|uniprotkb:Q71V68 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:ldb1_mouse(display_long)|uniprotkb:Ldb1(gene name)|psi-mi:Ldb1(display_short)|uniprotkb:Nli(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683373|imex:IM-28774-3065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) ensembl:ENSMUSG00000025223(gene)|ensembl:ENSMUST00000156585(transcript)|ensembl:ENSMUST00000185355(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060319"(primitive erythrocyte differentiation)|go:"GO:0060322"(head development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|rcsb pdb:4JCJ|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6PTL|reactome:R-MMU-8939236|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:P70662|rcsb pdb:1J2O|rcsb pdb:1M3V|rcsb pdb:1RUT|rcsb pdb:2JTN|rcsb pdb:2L6Y|rcsb pdb:2L6Z|rcsb pdb:2LXD|refseq:XP_011245459.1|refseq:NP_001106879.1|refseq:NP_034827.1|dip:DIP-42842N|entrezgene/locuslink:16825(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:TWjht9b9thCYJCr+CPgcUWJ4GN810090 rigid:ZOAEOWQ0KW38OIxD1//qoFaEx9I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:P79621 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683365|imex:IM-28774-2213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rigid:ek5sCegAQuKmddLNJXB6Z2b43IY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9D032 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-8006619|intact:MINT-2568056|uniprotkb:Q9EQP3|uniprotkb:Q99LC6|ensembl:ENSMUSP00000030367 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:ssbp3_mouse(display_long)|uniprotkb:Ssbp3(gene name)|psi-mi:Ssbp3(display_short)|uniprotkb:Last(gene name synonym)|uniprotkb:Ssdp1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym)|uniprotkb:Lck-associated signal transducer(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683357|imex:IM-28774-855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_940840.1|refseq:NP_076161.2|dip:DIP-42843N|ensembl:ENSMUSG00000061887(gene)|ensembl:ENSMUST00000030367(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0021501"(prechordal plate formation)|go:"GO:0021547"(midbrain-hindbrain boundary initiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0060322"(head development)|go:"GO:0060323"(head morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:2000744"(positive regulation of anterior head development)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9D032|entrezgene/locuslink:72475(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis comment:mint|function:"May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region" figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f410090 rigid:SMd6zbR8iBUYOgomLGmnzgtri0E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9D0P5 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-8607760|ensembl:ENSMUSP00000044368|intact:MINT-8177753 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:pygo1_mouse(display_long)|uniprotkb:Pygo1(gene name)|psi-mi:Pygo1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683349|imex:IM-28774-853 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000034910(gene)|ensembl:ENSMUST00000038489(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|rcsb pdb:2DX8|rcsb pdb:2YYR|reactome:R-MMU-201722|interpro:IPR019786|refseq:NP_082392.1|entrezgene/locuslink:72135(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:VcuyU94M5VkU3ooZ8t9278flbd410090 rigid:yPMbfHbrt5oY7kj4ij5B/HYtDds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9CYZ8 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683341|imex:IM-28774-3507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:wFVABx00cd8fbampTJy6V97b84U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9ES18 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26683305|ensembl:ENSMUSP00000003238|ensembl:ENSMUSP00000137645 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:foxj2_mouse(display_long)|uniprotkb:Fork head homologous X(gene name synonym)|uniprotkb:Foxj2(gene name)|psi-mi:Foxj2(display_short)|uniprotkb:Fhx(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683333|imex:IM-28774-3505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000003154(gene)|ensembl:ENSMUST00000003238(transcript)|ensembl:ENSMUST00000177927(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0110059"(negative regulation of blood vessel endothelial cell differentiation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_068699.1|entrezgene/locuslink:60611(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:dTCxDpS4XIhmZ9BQymYiN2D2AYw10090 rigid:p8Pm2501WETvH6AVwskmTDQ5keE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9JJG5 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26683270|ensembl:ENSMUSP00000090981|ensembl:ENSMUSP00000105214|ensembl:ENSMUSP00000105215|uniprotkb:Q8C609|uniprotkb:Q91WL3|uniprotkb:Q925E5 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:srtd2_mouse(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 2(gene name synonym)|uniprotkb:MNCb-1504(orf name)|uniprotkb:Sertad2(gene name)|psi-mi:Sertad2(display_short)|uniprotkb:Kiaa0127(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683297|imex:IM-28774-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000049800(gene)|ensembl:ENSMUST00000093292(transcript)|ensembl:ENSMUST00000109585(transcript)|ensembl:ENSMUST00000109586(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_001033714.1|refseq:NP_067347.2|refseq:XP_006514829.1|entrezgene/locuslink:58172(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:8LPkpBT1bp0sXQb7BYTftHHeBy010090 rigid:cORDjciESwZgqImx8T0FGzYG/PM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9WUL8 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683262|imex:IM-28774-3503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:1JVxN+yZLeIBpLvTfGum+cOiBHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9JL10 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26670122|ensembl:ENSMUSP00000008528|uniprotkb:Q925E6|uniprotkb:Q9D888 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:srtd1_mouse(display_long)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:Sertad1(gene name)|psi-mi:Sertad1(display_short)|uniprotkb:Sei1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683254|imex:IM-28774-1771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000008384(gene)|ensembl:ENSMUST00000008528(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|refseq:NP_061290.1|refseq:XP_006540280.1|entrezgene/locuslink:55942(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:6Sea4kPF+OhIUq18vLzpcRQ5eBU10090 rigid:PuJyJltNXO6KqvWPKhgcj2CBXSk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:G3X904 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683246|imex:IM-28774-3501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:NQPsTgQVWtjqCNT2CsVUSFw5oRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P15037 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-15859370|ensembl:ENSMUSP00000023612 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:ets2_mouse(display_long)|uniprotkb:Ets2(gene name)|psi-mi:Ets2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683238|imex:IM-28774-2651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR027276|interpro:IPR036388|interpro:IPR036390|reactome:R-MMU-2559585|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUSG00000022895(gene)|ensembl:ENSMUST00000023612(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_035939.3|dip:DIP-41847N|entrezgene/locuslink:23872(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:UQRN54oBxO1GUy/4QqUeTBVogXg10090 rigid:EWjfPLuGH374IMgY5sw0PG8LtcU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P15806 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683230|imex:IM-28774-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:Q8WpYzqQ9Wvt4GYRpUVNO2lQ97o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q04207 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683222|imex:IM-28774-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:K4vIEb8L8z7Es8cFAGs/0pv5Reg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P03966 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-647752|uniprotkb:Q61978|ensembl:ENSMUSP00000045993|ensembl:ENSMUSP00000114225 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:mycn_mouse(display_long)|uniprotkb:Mycn(gene name)|psi-mi:Mycn(display_short)|uniprotkb:Nmyc(gene name synonym)|uniprotkb:Nmyc1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683214|imex:IM-28774-2649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_032735.3|dip:DIP-49592N|ensembl:ENSMUSG00000037169(gene)|ensembl:ENSMUST00000043396(transcript)|ensembl:ENSMUST00000130990(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019900"(kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|entrezgene/locuslink:18109(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:J+RjU57FyHczGnzHYpNaUKOiw6k10090 rigid:6/74jCdeA1jb5eNVAMWypj04V1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q60795 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-642563|uniprotkb:Q3UQK0|ensembl:ENSMUSP00000099733 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:nf2l2_mouse(display_long)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)|uniprotkb:Nfe2l2(gene name)|psi-mi:Nfe2l2(display_short)|uniprotkb:Nrf2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683206|imex:IM-28774-3499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_035032.1|ensembl:ENSMUSG00000015839(gene)|ensembl:ENSMUST00000102672(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035690"|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046223"(aflatoxin catabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029845|rcsb pdb:1X2R|rcsb pdb:2DYH|rcsb pdb:3WN7|reactome:R-MMU-8932339|dip:DIP-49666N|entrezgene/locuslink:18024(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:flFH5+oCBXzNgfBzUiwuHtDQla810090 rigid:kttsUjlkjhbGVaLcnyyu+VBjqyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q05BA5 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683198|imex:IM-28774-2211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:xQnx+AbeIPeddiVCtdS35w6Pgp8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q07243 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26670765|ensembl:ENSMUSP00000030723|ensembl:ENSMUSP00000101799|uniprotkb:Q9JJW8 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:mtf1_mouse(display_long)|uniprotkb:MRE-binding transcription factor(gene name synonym)|uniprotkb:Transcription factor MTF-1(gene name synonym)|uniprotkb:Mtf1(gene name)|psi-mi:Mtf1(display_short)|uniprotkb:Mtf-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683190|imex:IM-28774-1769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000028890(gene)|ensembl:ENSMUST00000030723(transcript)|ensembl:ENSMUST00000106193(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:1990079"(cartilage homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029796|interpro:IPR036236|refseq:NP_032662.3|entrezgene/locuslink:17764(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:3a3aJs0bsRGzr9qHPcpSo5BxmBQ10090 rigid:pLD38wYDMhH0pgd8hYgaIGHoPxE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P09027 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26667584|ensembl:ENSMUSP00000044809|ensembl:ENSMUSP00000107613|ensembl:ENSMUSP00000107614|uniprotkb:Q3UUD3 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:hxd3_mouse(display_long)|uniprotkb:Homeobox protein Hox-4.1(gene name synonym)|uniprotkb:Homeobox protein MH-19(gene name synonym)|uniprotkb:Hoxd3(gene name)|psi-mi:Hoxd3(display_short)|uniprotkb:Hox-4.1(gene name synonym)|uniprotkb:Hoxd-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683182|imex:IM-28774-1335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000079277(gene)|ensembl:ENSMUST00000047830(transcript)|ensembl:ENSMUST00000111982(transcript)|ensembl:ENSMUST00000111983(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|go:"GO:0051216"(cartilage development)|refseq:NP_034598.2|entrezgene/locuslink:15434(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:o47Zd1IWzICvHRhhGN4cN2AQ+r010090 rigid:p3viZvV4wrqsKz1k39T0/M5KC8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P17919 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26683140|ensembl:ENSMUSP00000019117|uniprotkb:Q3ZAY6|uniprotkb:Q9CYH3 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:hxb1_mouse(display_long)|uniprotkb:Homeobox protein Hox-2.9(gene name synonym)|uniprotkb:Hoxb1(gene name)|psi-mi:Hoxb1(display_short)|uniprotkb:Hox-2.9(gene name synonym)|uniprotkb:Hoxb-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683174|imex:IM-28774-1767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000018973(gene)|ensembl:ENSMUST00000019117(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021546"(rhombomere development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_032292.3|entrezgene/locuslink:15407(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:a/QkzQGALd4g80HkFKZVR0wLmk010090 rigid:eQw4CoXESFd1s1kOp141XU+G79Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P31245 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-925434|ensembl:ENSMUSP00000014848|uniprotkb:Q149U3|uniprotkb:Q920T8 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:hxa2_mouse(display_long)|uniprotkb:Hoxa2(gene name)|psi-mi:Hoxa2(display_short)|uniprotkb:Hox-1.11(gene name synonym)|uniprotkb:Hoxa-2(gene name synonym)|uniprotkb:Homeobox protein Hox-1.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683132|imex:IM-28774-3063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000014704(gene)|ensembl:ENSMUST00000014848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0002076"(osteoblast development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007389"(pattern specification process)|refseq:NP_034581.1|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021568"(rhombomere 2 development)|go:"GO:0021569"(rhombomere 3 development)|go:"GO:0021658"(rhombomere 3 morphogenesis)|go:"GO:0035284"(brain segmentation)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15399(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:LWy5pZgpXhleM1hjwfSuftEtamE10090 rigid:5o7RlYPrkDr25bekx0aRd71pCSw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:B9EHK7 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26670915|ensembl:ENSMUSP00000000964 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:b9ehk7_mouse(display_long)|uniprotkb:Hoxa1(gene name)|psi-mi:Hoxa1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683124|imex:IM-28774-2209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000029844(gene)|ensembl:ENSMUST00000000964(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_034579.3|refseq:XP_006505670.1|entrezgene/locuslink:15394(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:LqWHYSQkWiAjpRFKLxRNNiC49DA10090 rigid:ACupHD3mvvtFrRCbRpd+kSkqgqc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q61545 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683116|imex:IM-28774-851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:LwMXCtBOVptilOTo0xiG71KwEOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P35639 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-10636142|uniprotkb:Q91YW9|ensembl:ENSMUSP00000026475 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:ddit3_mouse(display_long)|uniprotkb:Ddit3(gene name)|psi-mi:Ddit3(display_short)|uniprotkb:Chop(gene name synonym)|uniprotkb:Chop10(gene name synonym)|uniprotkb:Gadd153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA-damage-inducible protein GADD153(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683108|imex:IM-28774-3497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_001277112.1|refseq:NP_031863.3|refseq:XP_006513260.1|ensembl:ENSMUSG00000025408(gene)|ensembl:ENSMUST00000026475(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001955"(blood vessel maturation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|dip:DIP-60705N|entrezgene/locuslink:13198(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:ltrRdLwc8dwkKYkmxIAmq4iuFfA10090 rigid:J4qYusca/NkSjLpaPWz7O05CH7o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:P61458 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683100|imex:IM-28774-849 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rigid:pAwHoci6hJs1BysEZs/UP9jcG/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:P34056 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-11291520|uniprotkb:Q60740|uniprotkb:Q60741|uniprotkb:Q60742|uniprotkb:Q60743|uniprotkb:Q62067|uniprotkb:Q62068|uniprotkb:Q62069|uniprotkb:Q91VX0|uniprotkb:Q9CRY4 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:ap2a_mouse(display_long)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym)|uniprotkb:Tfap2a(gene name)|psi-mi:Tfap2a(display_short)|uniprotkb:Ap2tf(gene name synonym)|uniprotkb:Tcfap2a(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683413|imex:IM-28774-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001288603.1|refseq:NP_035677.2|reactome:R-MMU-8864260|reactome:R-MMU-8866904|reactome:R-MMU-8866907|reactome:R-MMU-8869496|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014032"(neural crest cell development)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043588"(skin development)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072210"(metanephric nephron development)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:0060235"(lens induction in camera-type eye)|entrezgene/locuslink:21418(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:wtUWkjAbUkwg6v86hs6AT0Lcjhs10090 rigid:3R3MWaZ7ICexbwBVl11nIT56Ea0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNY5 uniprotkb:P25490 intact:EBI-749023|ensembl:ENSP00000250076 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:zn232_human(display_long)|uniprotkb:Zinc finger and SCAN domain-containing protein 11(gene name synonym)|uniprotkb:ZNF232(gene name)|psi-mi:ZNF232(display_short)|uniprotkb:ZSCAN11(gene name synonym) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683573|imex:IM-28774-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055334.2|refseq:NP_001307882.1|refseq:NP_001307883.1|ensembl:ENSG00000167840(gene)|ensembl:ENST00000250076(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016880510.1|entrezgene/locuslink:7775(identity) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|entrezgene/locuslink:7528(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:18jIzxhG0JCfrQpWx8F7FkmYnQ09606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rigid:iT9+91+kcdoIMUio1FG7AuikpQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NYT6 uniprotkb:P18848 intact:EBI-20834409|ensembl:ENSP00000336719|ensembl:ENSP00000393265|ensembl:ENSP00000465121|uniprotkb:Q8WWE6|uniprotkb:Q96TE6|uniprotkb:Q9NS44 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:zn226_human(display_long)|uniprotkb:ZNF226(gene name)|psi-mi:ZNF226(display_short) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683565|imex:IM-28774-3515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000167380(gene)|ensembl:ENST00000337433(transcript)|ensembl:ENST00000454662(transcript)|ensembl:ENST00000590089(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001027544.1|refseq:NP_001027545.1|refseq:NP_001027546.1|refseq:NP_001139692.1|refseq:NP_001306017.1|refseq:NP_001306018.1|refseq:NP_001306019.1|refseq:NP_057003.2|refseq:NP_057528.2|refseq:XP_005259284.1|refseq:XP_006723430.1|refseq:XP_006723431.1|refseq:XP_006723432.1|refseq:XP_016882751.1|refseq:XP_016882754.1|entrezgene/locuslink:7769(identity) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity) - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:PUSlyfOnd/7j0DGp8yS+nRNrQVY9606 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:FRPq+zOkl42SBb2z+s4uSDCjjQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95125 uniprotkb:P61457 intact:EBI-751960|uniprotkb:Q4JG21|uniprotkb:Q9H1B9|uniprotkb:Q9NSM4|uniprotkb:B0LPH9|ensembl:ENSP00000337724|ensembl:ENSP00000432504|ensembl:ENSP00000433881 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zn202_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 10(gene name synonym)|uniprotkb:ZNF202(gene name)|psi-mi:ZNF202(display_short)|uniprotkb:ZKSCAN10(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683557|imex:IM-28774-861 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003446.2|refseq:XP_011541274.1|refseq:XP_011541275.1|refseq:XP_011541277.1|refseq:XP_011541278.1|refseq:XP_006718964.1|refseq:NP_001288708.1|refseq:NP_001288709.1|refseq:NP_001288748.1|refseq:XP_005271716.1|refseq:XP_005271717.1|refseq:XP_005271718.1|refseq:XP_005271721.1|refseq:XP_016873757.1|ensembl:ENSG00000166261(gene)|ensembl:ENST00000336139(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENST00000529691(transcript)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|ensembl:ENST00000530393(transcript)|entrezgene/locuslink:7753(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FXrtMKvDgz/dl5LmowdFVgYi65w9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:gWG6MFhck3IcddOQo/N+Yo9R5SU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14628 uniprotkb:P61457 intact:EBI-4395540|uniprotkb:A8K234|uniprotkb:B3KTK2|uniprotkb:B4DEL0|uniprotkb:Q0VAJ6|uniprotkb:Q658N8|uniprotkb:Q6ZNA9|uniprotkb:C9JLY9|uniprotkb:L7MNK2|ensembl:ENSP00000382511 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:zn195_human(display_long)|uniprotkb:ZNF195(gene name)|psi-mi:ZNF195(display_short)|uniprotkb:ZNFP104(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683549|imex:IM-28774-2663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123991.1|refseq:NP_001123992.1|refseq:NP_001229770.1|refseq:NP_001229771.1|refseq:NP_009083.2|refseq:NP_001229772.1|refseq:XP_016873752.1|refseq:NP_001243754.1|refseq:NP_001243752.1|refseq:NP_001243753.1|ensembl:ENSG00000005801(gene)|ensembl:ENST00000399602(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:7748(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:L28vWHahr3yXs1aXKhaHk2vsuFc9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:sqjsbtHEV6vU0NAZyrVXhL5Fd1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15535 uniprotkb:Q9HB58 intact:EBI-751531|uniprotkb:Q2TTR1|uniprotkb:B4E1W6|uniprotkb:E7EVQ2|ensembl:ENSP00000252207|ensembl:ENSP00000433402 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 psi-mi:zsc9_human(display_long)|uniprotkb:ZSCAN9(gene name)|psi-mi:ZSCAN9(display_short)|uniprotkb:Cell proliferation-inducing gene 12 protein(gene name synonym)|uniprotkb:PRD51(gene name synonym)|uniprotkb:ZNF193(gene name synonym)|uniprotkb:Zinc finger protein 193(gene name synonym)|uniprotkb:PIG12(orf name) psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683541|imex:IM-28774-2661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186409.1|refseq:NP_006290.1|refseq:NP_001186408.1|refseq:XP_016866756.1|ensembl:ENSG00000137185(gene)|ensembl:ENST00000252207(transcript)|ensembl:ENST00000531979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:O15535|entrezgene/locuslink:7746(identity) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|entrezgene/locuslink:3431(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NpEnjqbpSwof7YWBbMvQlSvkdeM9606 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rigid:6WFt5SrFt74GayeQL5Sq1ryVl/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99676 uniprotkb:Q01844 intact:EBI-3907489|uniprotkb:Q8TBA9|uniprotkb:B2R715|uniprotkb:O60792|ensembl:ENSP00000211936|ensembl:ENSP00000366636|ensembl:ENSP00000508298 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:zn184_human(display_long)|uniprotkb:ZNF184(gene name)|psi-mi:ZNF184(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683533|imex:IM-28774-3513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001334761.1|refseq:NP_009080.2|ensembl:ENSG00000096654(gene)|ensembl:ENST00000211936(transcript)|ensembl:ENST00000377419(transcript)|ensembl:ENST00000683788(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001305822.1|refseq:NP_001305820.1|refseq:NP_001305821.1|entrezgene/locuslink:7738(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/bpaBOHIfPjISqTOtI8PTNd9gPE9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:t3dfdkuT7ElBhbx26Wo/1xPLvSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BY02 uniprotkb:Q61545 intact:EBI-11519422|uniprotkb:A2A3V7|uniprotkb:Q8BJU5|uniprotkb:Q9CRL2|ensembl:ENSMUSP00000061546 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:nkrf_mouse(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Nkrf(gene name)|psi-mi:Nkrf(display_short)|uniprotkb:Nrf(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683525|imex:IM-28774-2659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084167.2|ensembl:ENSMUSG00000044149(gene)|ensembl:ENSMUST00000057093(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR034071|interpro:IPR036867|entrezgene/locuslink:77286(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EB0tfW7WDTGNkyHp9fMgZcVALJ410090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:v9X0mOsjcqylXmcOK+F+XM/lCfY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15697 uniprotkb:Q15697 intact:EBI-1210452|uniprotkb:Q9BQ34|uniprotkb:Q53Y68|ensembl:ENSP00000268655|ensembl:ENSP00000460397 intact:EBI-1210452|uniprotkb:Q9BQ34|uniprotkb:Q53Y68|ensembl:ENSP00000268655|ensembl:ENSP00000460397 psi-mi:zn174_human(display_long)|uniprotkb:ZNF174(gene name)|psi-mi:ZNF174(display_short)|uniprotkb:ZSCAN8(gene name synonym)|uniprotkb:AW-1(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 8(gene name synonym) psi-mi:zn174_human(display_long)|uniprotkb:ZNF174(gene name)|psi-mi:ZNF174(display_short)|uniprotkb:ZSCAN8(gene name synonym)|uniprotkb:AW-1(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 8(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683509|imex:IM-28774-1775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027463.1|refseq:NP_003441.1|refseq:NP_001334797.1|interpro:IPR038269|rcsb pdb:1Y7Q|ensembl:ENSG00000103343(gene)|ensembl:ENST00000268655(transcript)|ensembl:ENST00000571936(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027778|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|entrezgene/locuslink:7727(identity) refseq:NP_001027463.1|refseq:NP_003441.1|refseq:NP_001334797.1|interpro:IPR038269|rcsb pdb:1Y7Q|ensembl:ENSG00000103343(gene)|ensembl:ENST00000268655(transcript)|ensembl:ENST00000571936(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027778|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|entrezgene/locuslink:7727(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OotqJnbHr1LkdIoAnKfK0GrXhKo9606 rogid:OotqJnbHr1LkdIoAnKfK0GrXhKo9606 rigid:F6C94E2g/faNfJKs/OjsOFsCoUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14258 uniprotkb:P17028 intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym) psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683501|imex:IM-28774-859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|entrezgene/locuslink:7706(identity) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|entrezgene/locuslink:7572(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rigid:8JRTgF3o1EjhRmCLlk09Yyw025o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14258 uniprotkb:Q99697 intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961 intact:EBI-1175211|uniprotkb:O60578|uniprotkb:O60579|uniprotkb:O60580|uniprotkb:Q9BY17|ensembl:ENSP00000347004|ensembl:ENSP00000378095|ensembl:ENSP00000481951|ensembl:ENSP00000484763|uniprotkb:B2RA02|uniprotkb:B3KXS0|uniprotkb:Q3KQX9|uniprotkb:A8K6C6 psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym) psi-mi:pitx2_human(display_long)|uniprotkb:RIEG bicoid-related homeobox transcription factor(gene name synonym)|uniprotkb:Solurshin(gene name synonym)|uniprotkb:ALL1-responsive protein ARP1(gene name synonym)|uniprotkb:PITX2(gene name)|psi-mi:PITX2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:RGS(gene name synonym)|uniprotkb:RIEG(gene name synonym)|uniprotkb:RIEG1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 2(gene name synonym)|uniprotkb:Homeobox protein PITX2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683493|imex:IM-28774-3069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|entrezgene/locuslink:7706(identity) ensembl:ENSG00000164093(gene)|ensembl:ENST00000354925(transcript)|ensembl:ENST00000394595(transcript)|ensembl:ENST00000613094(transcript)|ensembl:ENST00000614423(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_000316.2|refseq:NP_001191326.1|refseq:NP_001191327.1|refseq:NP_001191328.1|refseq:NP_700475.1|refseq:NP_700476.1|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035993"(deltoid tuberosity development)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060127"(prolactin secreting cell differentiation)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061325"(cell proliferation involved in outflow tract morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070986"(left/right axis specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|mint:Q99697|rcsb pdb:2L7F|rcsb pdb:2L7M|rcsb pdb:2LKX|reactome:R-HSA-8866906|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:XP_011530329.1|entrezgene/locuslink:5308(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606 rogid:JWKFsTNDJOefVhq9VKgHa4A1C8g9606 rigid:smH+h3qWD1Q/Z6UHtDUjti3m5Os false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14258 uniprotkb:O14770 intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683485|imex:IM-28774-1339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|entrezgene/locuslink:7706(identity) ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N|entrezgene/locuslink:4212(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 rigid:GhdzWa+/IURXnpPBONzXB6wSLVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14258 uniprotkb:P15976 intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683477|imex:IM-28774-3511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|entrezgene/locuslink:7706(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:wAUcD8T5kRUJW1+8x52sYAfa78k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05516 uniprotkb:P08047 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683469|imex:IM-28774-2657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N|entrezgene/locuslink:7704(identity) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|entrezgene/locuslink:6667(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 rigid:0HX55+/f7TCa0c/mMrV6vcWid1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35227 uniprotkb:P31274 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683461|imex:IM-28774-857 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|entrezgene/locuslink:7703(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:4iEPltVmidcToTVx9AIiH4iMTVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q3U4B1 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683453|imex:IM-28774-3509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:xSx4sW1/ahZjJXsHK9nRcpU+jGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:Q9EP71 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-647227|uniprotkb:Q3URT3|uniprotkb:Q6ZPT6|ensembl:ENSMUSP00000087815|ensembl:ENSMUSP00000126325 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:rai14_mouse(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:Rai14(gene name)|psi-mi:Rai14(display_short)|uniprotkb:Kiaa1334(gene name synonym)|uniprotkb:Norpeg(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683445|imex:IM-28774-2655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) refseq:NP_001159880.1|refseq:NP_109615.1|refseq:XP_006520250.1|refseq:XP_006520251.1|refseq:XP_017172264.1|ensembl:ENSMUSG00000022246(gene)|ensembl:ENSMUST00000090339(transcript)|ensembl:ENSMUST00000169385(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9EP71|entrezgene/locuslink:75646(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:GjfwtzE2xp21+izEovwOKoUAlFY10090 rigid:OGy0YSKC0l/2XCd40hFD1nh9v9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:Q8CFD5 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683437|imex:IM-28774-2215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rigid:q+0Bkfp0w06fskfq7wS3LBWTxWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3U4B1 uniprotkb:Q9CPV7 intact:EBI-26666280|ensembl:ENSMUSP00000059039 intact:EBI-26680978|ensembl:ENSMUSP00000076157|ensembl:ENSMUSP00000153014|ensembl:ENSMUSP00000153404|uniprotkb:Q3U3I8|uniprotkb:Q3UT70|uniprotkb:Q544H1 psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:zdhc6_mouse(display_long)|uniprotkb:Stearoyltransferase ZDHHC6(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 6(gene name synonym)|uniprotkb:Zdhhc6(gene name)|psi-mi:Zdhhc6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683429|imex:IM-28774-1337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) go:"GO:0043543"(protein acylation)|go:"GO:0140439"(protein-cysteine S-stearoyltransferase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR036028|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000024982(gene)|ensembl:ENSMUST00000076891(transcript)|ensembl:ENSMUST00000224897(transcript)|ensembl:ENSMUST00000226103(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|refseq:NP_001028745.1|refseq:NP_080159.3|refseq:XP_006527331.1|refseq:XP_011245618.1|entrezgene/locuslink:66980(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rogid:S92KtJQU1Il4Lfq5Za4zTKPjoP010090 rigid:yPhaWNe1LXPFe8XBKSj9Kmc5+mA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06710 uniprotkb:Q16633 intact:EBI-2683132|uniprotkb:Q16339|uniprotkb:Q4ZG35|uniprotkb:Q96J49|uniprotkb:Q09155|uniprotkb:Q16337|uniprotkb:Q16338|ensembl:ENSP00000263334|ensembl:ENSP00000395498 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 psi-mi:pax8_human(display_long)|uniprotkb:PAX8(gene name)|psi-mi:PAX8(display_short) psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683581|imex:IM-28774-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003457.1|refseq:NP_039246.1|refseq:NP_039247.1|refseq:NP_054698.1|ensembl:ENSG00000125618(gene)|ensembl:ENST00000263334(transcript)|ensembl:ENST00000429538(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004996"(thyroid-stimulating hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|rcsb pdb:2K27|entrezgene/locuslink:7849(identity) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:57nZUvDfXt4KAf9YaCllERkaf3c9606 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rigid:VPXihbl6+fAIuIILuAjd1RyY/mM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20719 uniprotkb:Q9H9D4 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683731|imex:IM-28774-2221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719|entrezgene/locuslink:3202(identity) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412|entrezgene/locuslink:79797(identity) - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rigid:ZJIDheVTM2WoHckhviOu9Gezfoc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:P17482 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683739|imex:IM-28774-2223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412|entrezgene/locuslink:79797(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:81VwYSr+Y+5OSybCLR5badF8Z8s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0AVK6 uniprotkb:Q01844 intact:EBI-7779316|ensembl:ENSP00000250024|ensembl:ENSP00000434199|ensembl:ENSP00000481103|uniprotkb:Q8N340|uniprotkb:Q5BKY4|intact:MINT-6541611|uniprotkb:Q9H5M0|uniprotkb:Q3C1U6|uniprotkb:Q2VPJ3|uniprotkb:A8K9H3 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:e2f8_human(display_long)|uniprotkb:E2F8(gene name)|psi-mi:E2F8(display_short) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683715|imex:IM-28774-3071 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|mint:A0AVK6|rcsb pdb:4YO2|reactome:R-HSA-6804116|go:"GO:0070365"(hepatocyte differentiation)|ensembl:ENSG00000129173(gene)|ensembl:ENST00000250024(transcript)|ensembl:ENST00000527884(transcript)|ensembl:ENST00000620009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|refseq:NP_001243301.1|refseq:NP_001243300.1|refseq:NP_078956.2|entrezgene/locuslink:79733(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - function:Inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Modulates the activity of other E2F proteins, such as E2F1, probably by competing or displacing activating E2Fs from promoter binding|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8RCzz+HuzFPNJ4soR6lxKkq17BU9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:M7e+hZXT2qDS5rHVdF3zZ4sQfjA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5H4 uniprotkb:Q9NRM2 intact:EBI-1210580|uniprotkb:Q569L7|uniprotkb:Q96CX4|ensembl:ENSP00000369777 intact:EBI-949305|ensembl:ENSP00000354501|uniprotkb:Q75MZ2|uniprotkb:Q75MZ3|uniprotkb:Q8WY14 psi-mi:zn768_human(display_long)|uniprotkb:ZNF768(gene name)|psi-mi:ZNF768(display_short) psi-mi:zn277_human(display_long)|uniprotkb:ZNF277(gene name)|psi-mi:ZNF277(display_short)|uniprotkb:ZNF277P(gene name synonym)|uniprotkb:NRIF4(gene name synonym)|uniprotkb:Nuclear receptor-interacting factor 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683707|imex:IM-28774-2219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078947.3|ensembl:ENSG00000169957(gene)|ensembl:ENST00000380412(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H5H4|entrezgene/locuslink:79724(identity) ensembl:ENSG00000198839(gene)|ensembl:ENST00000361822(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR040048|interpro:IPR041661|refseq:NP_068834.2|entrezgene/locuslink:11179(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:kQWxrEzummMO3IQ8wdpnXWFJn1o9606 rogid:LH60QmqqTZD5rgMq1hXWbyCO09s9606 rigid:vSzltM+1jOdy0QUCQYdkt1BF2m8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D2H6 uniprotkb:Q9D2H6 intact:EBI-26674949|uniprotkb:Q6A0E1 intact:EBI-26674949|uniprotkb:Q6A0E1 psi-mi:sp2_mouse(display_long)|uniprotkb:Sp2(gene name)|psi-mi:Sp2(display_short)|uniprotkb:Kiaa0048(gene name synonym) psi-mi:sp2_mouse(display_long)|uniprotkb:Sp2(gene name)|psi-mi:Sp2(display_short)|uniprotkb:Kiaa0048(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683691|imex:IM-28774-2667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072359"(circulatory system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_001074433.1|refseq:NP_084496.2|interpro:IPR030451|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:78912(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072359"(circulatory system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_001074433.1|refseq:NP_084496.2|interpro:IPR030451|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:78912(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:UcPZ7bur3a/CDkDAeAP1GvD5Pvg10090 rogid:UcPZ7bur3a/CDkDAeAP1GvD5Pvg10090 rigid:VDU4R4VOKLFhvwJnZtTJlWek74M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VHS6 uniprotkb:G3X904 intact:EBI-26675998|ensembl:ENSMUSP00000031696|ensembl:ENSMUSP00000112965|uniprotkb:Q8CDP8 intact:EBI-26667657|ensembl:ENSMUSP00000033731 psi-mi:asb15_mouse(display_long)|uniprotkb:Asb15(gene name)|psi-mi:Asb15(display_short) psi-mi:g3x904_mouse(display_long)|uniprotkb:Zfp275(gene name)|psi-mi:Zfp275(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683683|imex:IM-28774-2217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029685(gene)|ensembl:ENSMUST00000031696(transcript)|ensembl:ENSMUST00000117688(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|refseq:NP_543123.2|refseq:XP_011239391.1|entrezgene/locuslink:78910(identity) ensembl:ENSMUSG00000031365(gene)|ensembl:ENSMUST00000033731(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_113682.2|entrezgene/locuslink:27081(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:k90YXTebsFC0kF2V8wAQe54DFVM10090 rogid:eml4+oyM/jTl1Pygxts2pHhHsK810090 rigid:udIEE6ZnWnquvQ/KM2c29OfJpPU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:Q8VHS6 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-26675998|ensembl:ENSMUSP00000031696|ensembl:ENSMUSP00000112965|uniprotkb:Q8CDP8 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:asb15_mouse(display_long)|uniprotkb:Asb15(gene name)|psi-mi:Asb15(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683666|imex:IM-28774-1779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000029685(gene)|ensembl:ENSMUST00000031696(transcript)|ensembl:ENSMUST00000117688(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|refseq:NP_543123.2|refseq:XP_011239391.1|entrezgene/locuslink:78910(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:k90YXTebsFC0kF2V8wAQe54DFVM10090 rigid:zyyf6sJZZbuF+5eHunIsTIt8UIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EQN3 uniprotkb:O55144 intact:EBI-7821198|ensembl:ENSMUSP00000098107|intact:UNK-5545632|uniprotkb:Q99PD5|uniprotkb:Q9D2V9 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:t22d4_mouse(display_long)|uniprotkb:Thg-1pit(gene name synonym)|uniprotkb:Thg1pit(gene name synonym)|uniprotkb:Tsc22d4(gene name)|psi-mi:Tsc22d4(display_short)|uniprotkb:Tilz2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683658|imex:IM-28774-865 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029723(gene)|ensembl:ENSMUST00000100539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|refseq:NP_076399.4|entrezgene/locuslink:78829(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - comment:mint|function:Transcriptional repressor|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BzEbOgzNJndbsPWXDDG9/TFIHBY10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:L+lY3syYosmO4ACsMl99U1soyCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:B2RRD7 uniprotkb:Q04207 intact:EBI-26683597|ensembl:ENSMUSP00000108747 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:brpf1_mouse(display_long)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Brpf1(gene name)|psi-mi:Brpf1(display_short) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683650|imex:IM-28774-2665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000001632(gene)|ensembl:ENSMUST00000113122(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|reactome:R-MMU-3214847|reactome:R-MMU-6804758|refseq:NP_001269056.1|refseq:XP_006506851.1|entrezgene/locuslink:78783(identity) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|entrezgene/locuslink:19697(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HFRSwqkAq5mb93TT+7f4yUrkiE810090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rigid:LI0e60pU7HYp/F268s2ErqX5hHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61458 uniprotkb:B2RRD7 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 intact:EBI-26683597|ensembl:ENSMUSP00000108747 psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:brpf1_mouse(display_long)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Brpf1(gene name)|psi-mi:Brpf1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683642|imex:IM-28774-3517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1|entrezgene/locuslink:13180(identity) ensembl:ENSMUSG00000001632(gene)|ensembl:ENSMUST00000113122(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|reactome:R-MMU-3214847|reactome:R-MMU-6804758|refseq:NP_001269056.1|refseq:XP_006506851.1|entrezgene/locuslink:78783(identity) - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 rogid:HFRSwqkAq5mb93TT+7f4yUrkiE810090 rigid:la3zPcgSlSdtWw9sClp+PU+gQzs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55201 uniprotkb:P32780 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683589|imex:IM-28774-863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N|entrezgene/locuslink:7862(identity) refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N|entrezgene/locuslink:2965(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:zGCN6v33sL2fJECYUftHkIUopQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:Q3U4B1 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684038|imex:IM-28774-3525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:zC0y5El0/TGEp3T6XReGyx1nlQw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:P15806 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-81370|uniprotkb:Q3U153|uniprotkb:Q8CAH9|uniprotkb:Q8VCY4|uniprotkb:Q922S2|uniprotkb:Q99MB8|uniprotkb:Q9CYJ4|ensembl:ENSMUSP00000100983 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:tfe2_mouse(display_long)|uniprotkb:Tcf3(gene name)|psi-mi:Tcf3(display_short)|uniprotkb:Alf2(gene name synonym)|uniprotkb:Me2(gene name synonym)|uniprotkb:Tcfe2a(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Transcription factor A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684030|imex:IM-28774-1347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) rcsb pdb:2QL2|reactome:R-MMU-525793|reactome:R-MMU-8939236|refseq:NP_001157620.1|refseq:NP_001157621.1|refseq:NP_001157623.1|refseq:NP_035678.3|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048468"(cell development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15806|ensembl:ENSMUSG00000020167(gene)|ensembl:ENSMUST00000105346(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-30940N|entrezgene/locuslink:21423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:aMvLmcfudacIqIAxOSmbNPNjsc810090 rigid:L12JkkPXJzigI+mhaz0IGY2wpQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:Q3TYI2 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-26672300 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:q3tyi2_mouse(display_long)|uniprotkb:Polr2j(gene name)|psi-mi:Polr2j(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684022|imex:IM-28774-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_035423.2|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|entrezgene/locuslink:20022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:lVeRAU7ZwTpO9drt04ywfrfbUA410090 rigid:GQfU0QZu5dWJJYitru2knItQZYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:Q3TYI2 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-26672300 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:q3tyi2_mouse(display_long)|uniprotkb:Polr2j(gene name)|psi-mi:Polr2j(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684014|imex:IM-28774-1795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0046983"(protein dimerization activity)|refseq:NP_035423.2|interpro:IPR037685|interpro:IPR036603|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|entrezgene/locuslink:20022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:lVeRAU7ZwTpO9drt04ywfrfbUA410090 rigid:GQfU0QZu5dWJJYitru2knItQZYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:Q07279 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684006|imex:IM-28774-879 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:f81PPDilf0LGlqY2XMnUn62Zk6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:P97368 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-925694|uniprotkb:Q149R5|uniprotkb:Q99L81|ensembl:ENSMUSP00000002495 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:meis3_mouse(display_long)|uniprotkb:Meis3(gene name)|psi-mi:Meis3(display_short)|uniprotkb:Mrg2(gene name synonym)|uniprotkb:Meis1-related protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683998|imex:IM-28774-1345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) refseq:NP_032653.2|refseq:NP_001289401.1|refseq:XP_006539666.1|refseq:NP_001264917.1|refseq:NP_001264918.1|ensembl:ENSMUSG00000041420(gene)|ensembl:ENSMUST00000002495(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17537(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:Yu1LnYMFa21iCQS6XzlUkJQYkAM10090 rigid:EC41tljMZ8Y650GVh7+A/CP5uhc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:P97367 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-925634|uniprotkb:O35676|uniprotkb:O35677|uniprotkb:P97403|uniprotkb:P97404|ensembl:ENSMUSP00000028639 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:meis2_mouse(display_long)|uniprotkb:Meis2(gene name)|psi-mi:Meis2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Stra10(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683990|imex:IM-28774-2233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) refseq:NP_001129544.1|refseq:NP_001153039.1|refseq:NP_001153040.1|refseq:NP_034955.1|ensembl:ENSMUSG00000027210(gene)|ensembl:ENSMUST00000028639(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17536(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:yJ9cUK38d7spHi/8UAQZQfVFZ/810090 rigid:aa4ORTo/B3yjI5RuJTpA8TAz5o0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99NE9 uniprotkb:Q60954 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 intact:EBI-445706|uniprotkb:B1ARH5|uniprotkb:Q60955|uniprotkb:Q8CIL0|uniprotkb:Q5SVC8|ensembl:ENSMUSP00000069277 psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:meis1_mouse(display_long)|uniprotkb:Myeloid ecotropic viral integration site 1(gene name synonym)|uniprotkb:Meis1(gene name)|psi-mi:Meis1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683982|imex:IM-28774-1793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) refseq:NP_001180200.1|refseq:NP_034919.1|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:Q60954|ensembl:ENSMUSG00000020160(gene)|ensembl:ENSMUST00000068264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001654"(eye development)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0043565"(sequence-specific DNA binding)|entrezgene/locuslink:17268(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rogid:RGSZw4Y6pNk7d/7zSj0rItFpMGc10090 rigid:ZjQ/9sFwNt7nyNTUv/kLRIVnsxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99LJ2 uniprotkb:Q8CGW9 intact:EBI-26683939|uniprotkb:Q8C2K7|uniprotkb:Q91XU4 intact:EBI-26667902|ensembl:ENSMUSP00000011493|uniprotkb:A6H6T0 psi-mi:abtb1_mouse(display_long)|uniprotkb:Abtb1(gene name)|psi-mi:Abtb1(display_short)|uniprotkb:Bpoz(gene name synonym) psi-mi:dmrtd_mouse(display_long)|uniprotkb:Doublesex- and mab-3-related transcription factor 7(gene name synonym)|uniprotkb:Dmrtc2(gene name)|psi-mi:Dmrtc2(display_short)|uniprotkb:Dmrt7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683974|imex:IM-28774-1343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR044515|refseq:NP_084527.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:80283(identity) go:"GO:0007548"(sex differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR031577|interpro:IPR036407|ensembl:ENSMUSG00000011349(gene)|ensembl:ENSMUST00000011493(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007141"(male meiosis I)|go:"GO:0007281"(germ cell development)|go:"GO:0007290"(spermatid nucleus elongation)|refseq:NP_082008.1|refseq:XP_006540422.1|entrezgene/locuslink:71241(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9/LUxirBm93cS+dlsTNHo2HEEOA10090 rogid:hRSPMVHJPYWX1lpYdvQQTrb7dgg10090 rigid:k8Wy0cOQo+ESS9I06FokdmoG9gU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99LJ2 uniprotkb:O55144 intact:EBI-26683939|uniprotkb:Q8C2K7|uniprotkb:Q91XU4 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:abtb1_mouse(display_long)|uniprotkb:Abtb1(gene name)|psi-mi:Abtb1(display_short)|uniprotkb:Bpoz(gene name synonym) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683966|imex:IM-28774-2669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR044515|refseq:NP_084527.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:80283(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9/LUxirBm93cS+dlsTNHo2HEEOA10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:VO8ziZZdEB752RK7JB9z36jaWto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99LJ2 uniprotkb:Q61545 intact:EBI-26683939|uniprotkb:Q8C2K7|uniprotkb:Q91XU4 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:abtb1_mouse(display_long)|uniprotkb:Abtb1(gene name)|psi-mi:Abtb1(display_short)|uniprotkb:Bpoz(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683958|imex:IM-28774-1791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR044515|refseq:NP_084527.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:80283(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9/LUxirBm93cS+dlsTNHo2HEEOA10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:rXzJ9oz1AdUGO6uHWPbw6dKUJEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZN57 uniprotkb:Q15744 intact:EBI-7236323|uniprotkb:A5PLN5|uniprotkb:B7ZM23|intact:MINT-1199669|uniprotkb:Q9H6Z6|ensembl:ENSP00000354453|ensembl:ENSP00000430531|ensembl:ENSP00000430980 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:zfp2_human(display_long)|uniprotkb:ZFP2(gene name)|psi-mi:ZFP2(display_short)|uniprotkb:ZNF751(gene name synonym)|uniprotkb:Zinc finger protein 751(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683931|imex:IM-28774-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085116.2|ensembl:ENSG00000198939(gene)|ensembl:ENST00000361362(transcript)|ensembl:ENST00000520301(transcript)|ensembl:ENST00000523286(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:80108(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - comment:mint|comment:homomint|function:Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:IpvoJkjjdMAy1IBCicP3URazNpg9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:DM+ly8fcogZTGpjpZmKWT9XnuEc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9HAH1 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-21784179|uniprotkb:Q96GM3|ensembl:ENSP00000302603 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:zn556_human(display_long)|uniprotkb:ZNF556(gene name)|psi-mi:ZNF556(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683923|imex:IM-28774-1789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001287772.1|refseq:NP_079243.1|ensembl:ENSG00000172000(gene)|ensembl:ENST00000307635(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:80032(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:slcCwLRUiVbXurXA8y+ChhrWHIA9606 rigid:UUySQ0Y78gcN4+J5XbBKV/Z/x9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N9V6 uniprotkb:Q8N653 intact:EBI-13628901|ensembl:ENSP00000353796|uniprotkb:Q8IYP8 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:anr53_human(display_long)|uniprotkb:ANKRD53(gene name)|psi-mi:ANKRD53(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683915|imex:IM-28774-3077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144031(gene)|ensembl:ENST00000360589(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:1902412"(regulation of mitotic cytokinesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042335|refseq:NP_001108588.1|refseq:NP_079209.3|entrezgene/locuslink:79998(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W09QRqS3g+cxv4JH88LiBotM0sE9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:PpKcBrCHMZ4Sev/CSEOnKuPA2fQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:O60841 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-928530|uniprotkb:O95805|uniprotkb:Q9UF81|uniprotkb:Q9UMN7|uniprotkb:Q53RV7|uniprotkb:Q53SI8|ensembl:ENSP00000289371 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:if2p_human(display_long)|uniprotkb:EIF5B(gene name)|psi-mi:EIF5B(display_short)|uniprotkb:IF2(gene name synonym)|uniprotkb:KIAA0741(gene name synonym)|uniprotkb:Translation initiation factor IF-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683907|imex:IM-28774-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_056988.3|ensembl:ENSG00000158417(gene)|ensembl:ENST00000289371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|mint:O60841|reactome:R-HSA-72706|entrezgene/locuslink:9669(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:5rLXO0ZcDcwLGOM4ZGA4fvQJ33U9606 rigid:WWwakvCknwfPWuL4C+0CLQlIC3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9Y6K9 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683899|imex:IM-28774-2231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:KEf7okI2/TKGqz7XWg8xqjKuers false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9UBW7 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683891|imex:IM-28774-1787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1|entrezgene/locuslink:7750(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 rigid:C3J7e6U6SH7VwQlkqrVHeaI64qY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:P10827 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-286285|uniprotkb:P21205|uniprotkb:Q8N6A1|uniprotkb:Q96H73|uniprotkb:A8K3B5|ensembl:ENSP00000264637|ensembl:ENSP00000377679 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:tha_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:EAR7(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:ERBA1(gene name synonym)|uniprotkb:NR1A1(gene name synonym)|uniprotkb:THRA1(gene name synonym)|uniprotkb:THRA2(gene name synonym)|uniprotkb:V-erbA-related protein 7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683883|imex:IM-28774-1341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001177847.1|refseq:NP_001177848.1|refseq:NP_003241.2|refseq:NP_955366.1|dip:DIP-31452N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1NAV|rcsb pdb:2H77|rcsb pdb:2H79|rcsb pdb:3HZF|rcsb pdb:3ILZ|rcsb pdb:3JZB|rcsb pdb:4LNW|rcsb pdb:4LNX|reactome:R-HSA-383280|reactome:R-HSA-4090294|ensembl:ENSG00000126351(gene)|ensembl:ENST00000264637(transcript)|ensembl:ENST00000394121(transcript)|entrezgene/locuslink:7067(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:u1B3u6XbEyC3OKOWr25s9qZYe4o9606 rigid:HcBkKJ3H+fi9pkmR56q5m72afyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:O00267 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683875|imex:IM-28774-877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:mHwWcNzMaurkFrRWrPXLaOQpaDE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q92786 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-3912635|uniprotkb:Q8TB91|uniprotkb:A6NK29|uniprotkb:Q5SW76|uniprotkb:A8K2B1|ensembl:ENSP00000261454|ensembl:ENSP00000355925|ensembl:ENSP00000400694|ensembl:ENSP00000420283 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:prox1_human(display_long)|uniprotkb:PROX1(gene name)|psi-mi:PROX1(display_short)|uniprotkb:Homeobox prospero-like protein PROX1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683867|imex:IM-28774-3075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_002754.2|refseq:NP_001257545.1|ensembl:ENSG00000117707(gene)|ensembl:ENST00000261454(transcript)|ensembl:ENST00000366958(transcript)|ensembl:ENST00000435016(transcript)|ensembl:ENST00000498508(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002194"(hepatocyte cell migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030324"(lung development)|go:"GO:0030910"(olfactory placode formation)|go:"GO:0031016"(pancreas development)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043049"(otic placode formation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046619"(lens placode formation involved in camera-type eye formation)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0055005"(ventricular cardiac myofibril assembly)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060214"(endocardium formation)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060836"(lymphatic endothelial cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|go:"GO:0061114"(branching involved in pancreas morphogenesis)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070858"(negative regulation of bile acid biosynthetic process)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090425"(acinar cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1901978"(positive regulation of cell cycle checkpoint)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000979"(positive regulation of forebrain neuron differentiation)|interpro:IPR007738(Homeobox prospero-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR023082|interpro:IPR037131|interpro:IPR039350|mint:Q92786|rcsb pdb:2LMD|refseq:XP_016857322.1|entrezgene/locuslink:5629(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:80GpGEDggRkdm+tl6WhIz3FDfos9606 rigid:8JCMCcSnTjN4DD9wsLTfyeMq96M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:P37231 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683859|imex:IM-28774-2229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:h3f1lEwuLN7w8cRqyYyWA62c/mA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:P55347 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683851|imex:IM-28774-2227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472|entrezgene/locuslink:5316(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606 rigid:cLFyU6VkDQ8J0XG0UtZL77YTsJ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9UJU2 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-926131|uniprotkb:B4DG38|uniprotkb:Q3ZCU4|uniprotkb:Q9HAZ0|uniprotkb:B7Z8E2|uniprotkb:E9PDK3|ensembl:ENSP00000265165 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:lef1_human(display_long)|uniprotkb:LEF1(gene name)|psi-mi:LEF1(display_short)|uniprotkb:T cell-specific transcription factor 1-alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683843|imex:IM-28774-3523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001124185.1|refseq:NP_001124186.1|refseq:NP_001159591.1|refseq:NP_057353.1|ensembl:ENSG00000138795(gene)|ensembl:ENST00000265165(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0021873"(forebrain neuroblast division)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|dip:DIP-29946N|go:"GO:0030879"(mammary gland development)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0042100"(B cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0060033"(anatomical structure regression)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0061153"(trachea gland development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR028769|interpro:IPR036910|mint:Q9UJU2|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-8853884|reactome:R-HSA-8951430|reactome:R-HSA-9616222|go:"GO:0140416"(transcription regulator inhibitor activity)|entrezgene/locuslink:51176(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:UWp+cETOgprhC0+wuj8BYycu2vU9606 rigid:+621oDKYUKZH4UtPfPeYs8xz0cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:P84022 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683835|imex:IM-28774-875 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828|entrezgene/locuslink:4088(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:kqocJKEXeeQOfNJBN+mOZmZRtz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:O14896 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-6115643|uniprotkb:B4DLE2|uniprotkb:F5GWX8|uniprotkb:D3DT90|uniprotkb:G0ZTL0|ensembl:ENSP00000355988 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:irf6_human(display_long)|uniprotkb:IRF6(gene name)|psi-mi:IRF6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683827|imex:IM-28774-1785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_006138.1|refseq:NP_001193625.1|ensembl:ENSG00000117595(gene)|ensembl:ENST00000367021(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-877300|reactome:R-HSA-909733|entrezgene/locuslink:3664(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:JYC5lgxa30lVPAoMBZEpRItqo089606 rigid:rIuVj9rKylT0dWQ8tPG3m+Xii0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q9H5J0 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683819|imex:IM-28774-3521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) - - function:May be involved in transcriptional regulation|comment:mint|comment:homomint figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rigid:xWXSfsPMWvbhXrojbPjcXRjQW/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:O00499 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683811|imex:IM-28774-873 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N|entrezgene/locuslink:274(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:2zmefbTvonpE9KW+tpzejL1RXjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9GZV1 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-12111292|ensembl:ENSP00000306163|uniprotkb:Q3B778|uniprotkb:Q5T456|uniprotkb:Q70EZ9|uniprotkb:Q8WUD7|uniprotkb:Q96MG0|uniprotkb:Q9NQC9 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:ankr2_human(display_long)|uniprotkb:ANKRD2(gene name)|psi-mi:ANKRD2(display_short)|uniprotkb:ARPP(gene name synonym)|uniprotkb:Skeletal muscle ankyrin repeat protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683803|imex:IM-28774-1783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) ensembl:ENSG00000165887(gene)|ensembl:ENST00000307518(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016605"(PML body)|go:"GO:0031674"(I band)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR036770|refseq:NP_001333726.1|refseq:NP_001123453.1|refseq:NP_001278147.1|refseq:NP_065082.2|refseq:NP_001278148.2|entrezgene/locuslink:26287(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:XKdt7K4PJe3I+OhZuEz9turolqI9606 rigid:BbyIRj7BIUSaB98Ugo4Bhgn8DY0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:P43694 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-7049352|uniprotkb:B7ZKZ4|ensembl:ENSP00000334458|ensembl:ENSP00000482268|ensembl:ENSP00000495511|uniprotkb:Q5IFM8|intact:MINT-3379484|uniprotkb:Q3MJ45|uniprotkb:B7ZKX0 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:gata4_human(display_long)|uniprotkb:GATA4(gene name)|psi-mi:GATA4(display_short)|uniprotkb:GATA-binding factor 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683795|imex:IM-28774-3073 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001295022.1|refseq:XP_011542119.1|refseq:XP_011542120.1|ensembl:ENSG00000136574(gene)|ensembl:ENSG00000285109(gene)|ensembl:ENST00000335135(transcript)|ensembl:ENST00000622443(transcript)|ensembl:ENST00000647274(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0033189"(response to vitamin A)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|mint:P43694|rcsb pdb:2M9W|reactome:R-HSA-2032785|reactome:R-HSA-400511|reactome:R-HSA-5578768|reactome:R-HSA-9690406|reactome:R-HSA-983231|refseq:XP_016868801.1|refseq:NP_002043.2|refseq:XP_005272442.1|refseq:XP_005272443.1|refseq:XP_006716311.1|entrezgene/locuslink:2626(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint function:"Defects in GATA4 are the cause of atrial septal defect type 2 (ASD2) [MIM:607941]. ASD2 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. ASD2 patients show other heart abnormalities including ventricular and atrioventricular septal defects, pulmonary valve thickening or insufficiency of the cardiac valves. ASD2 is not associated with defects in the cardiac conduction system or non-cardiac abnormalities"|comment:mint|function:Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:lzfeBDLcKGZXrcnJzaVRQrJnfpE9606 rigid:6LlS+ARfvrSu2oeupGDfjgSaPq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9NQC1 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q6IE80|uniprotkb:Q96GQ6|ensembl:ENSP00000378451 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683787|imex:IM-28774-1781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|mint:Q9NQC1|reactome:R-HSA-3214847|entrezgene/locuslink:23338(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 rigid:mlqgeB2XmnfUZ2JYLk547v2j6jU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q08050 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-866480|uniprotkb:O43258|uniprotkb:O43259|uniprotkb:O43260|uniprotkb:Q4ZGG7|uniprotkb:Q9BRL2|ensembl:ENSP00000352901 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:foxm1_human(display_long)|uniprotkb:Hepatocyte nuclear factor 3 forkhead homolog 11(gene name synonym)|uniprotkb:Winged-helix factor from INS-1 cells(gene name synonym)|uniprotkb:M-phase phosphoprotein 2(gene name synonym)|uniprotkb:MPM-2 reactive phosphoprotein 2(gene name synonym)|uniprotkb:Transcription factor Trident(gene name synonym)|uniprotkb:Forkhead-related protein FKHL16(gene name synonym)|uniprotkb:WIN(gene name synonym)|uniprotkb:FOXM1(gene name)|psi-mi:FOXM1(display_short)|uniprotkb:FKHL16(gene name synonym)|uniprotkb:HFH11(gene name synonym)|uniprotkb:MPP2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683779|imex:IM-28774-2225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_068772.2|refseq:NP_973731.1|refseq:NP_973732.1|refseq:NP_001230017.1|refseq:NP_001230018.1|dip:DIP-36754N|ensembl:ENSG00000111206(gene)|ensembl:ENST00000359843(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|interpro:IPR042839|rcsb pdb:3G73|reactome:R-HSA-156711|reactome:R-HSA-69273|entrezgene/locuslink:2305(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:u1jKIeT/XYuwT7KzYJbwdQXq7hM9606 rigid:6MLNxU5o7WvAuvJhovMCdxm67qA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q9UNN4 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-10229384|uniprotkb:Q53FD9|uniprotkb:Q5D050|uniprotkb:B4DY14|ensembl:ENSP00000384597 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:tf2ay_human(display_long)|uniprotkb:GTF2A1L(gene name)|psi-mi:GTF2A1L(display_short)|uniprotkb:ALF(gene name synonym)|uniprotkb:GTF2A1LF(gene name synonym)|uniprotkb:General transcription factor II A, 1-like factor(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683771|imex:IM-28774-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_001180416.1|refseq:NP_006863.2|ensembl:ENSG00000242441(gene)|ensembl:ENST00000403751(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0050890"(cognition)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|entrezgene/locuslink:11036(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:1uaon8Xsix/TU/vi5ByqfUbYI249606 rigid:3IoLjWlf7Dk8/v0Jq2yz9AI8Y7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H5J0 uniprotkb:Q99909 intact:EBI-7229473|intact:MINT-1197980|ensembl:ENSP00000501025 intact:EBI-10295431|uniprotkb:O60223|uniprotkb:Q9BRW7|uniprotkb:Q5JQZ3|ensembl:ENSP00000298396 psi-mi:zbtb3_human(display_long)|uniprotkb:ZBTB3(gene name)|psi-mi:ZBTB3(display_short) psi-mi:ssx3_human(display_long)|uniprotkb:SSX3(gene name)|psi-mi:SSX3(display_short)|uniprotkb:Cancer/testis antigen 5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683763|imex:IM-28774-871 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079060.1|ensembl:ENSG00000185670(gene)|ensembl:ENST00000673933(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|entrezgene/locuslink:79842(identity) refseq:NP_066294.1|refseq:XP_011542187.1|ensembl:ENSG00000165584(gene)|ensembl:ENST00000298396(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:10214(identity) - function:May be involved in transcriptional regulation|comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5Fayrr9LFS1Yw1QZ0q94xYz12c89606 rogid:jSB31TCCfnAP7jshF00a7bTb/sA9606 rigid:BgtMSdoU8UXzFDarShkN71sbzk4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9B1 uniprotkb:Q8N653 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683755|imex:IM-28774-3519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|entrezgene/locuslink:79813(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:jIcM1um3TQicJ3Y0ystwxxhD6aw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9B1 uniprotkb:P61457 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683747|imex:IM-28774-869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|entrezgene/locuslink:79813(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:a84cAWOk1NGtHP74pTr4e/aR8ls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A0AVK6 uniprotkb:Q8N653 intact:EBI-7779316|ensembl:ENSP00000250024|ensembl:ENSP00000434199|ensembl:ENSP00000481103|uniprotkb:Q8N340|uniprotkb:Q5BKY4|intact:MINT-6541611|uniprotkb:Q9H5M0|uniprotkb:Q3C1U6|uniprotkb:Q2VPJ3|uniprotkb:A8K9H3 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:e2f8_human(display_long)|uniprotkb:E2F8(gene name)|psi-mi:E2F8(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683723|imex:IM-28774-867 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|mint:A0AVK6|rcsb pdb:4YO2|reactome:R-HSA-6804116|go:"GO:0070365"(hepatocyte differentiation)|ensembl:ENSG00000129173(gene)|ensembl:ENST00000250024(transcript)|ensembl:ENST00000527884(transcript)|ensembl:ENST00000620009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|refseq:NP_001243301.1|refseq:NP_001243300.1|refseq:NP_078956.2|entrezgene/locuslink:79733(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - function:Inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Modulates the activity of other E2F proteins, such as E2F1, probably by competing or displacing activating E2Fs from promoter binding|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8RCzz+HuzFPNJ4soR6lxKkq17BU9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:CCOoMHguTLUjMPY/E+tNt3IKUGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60898 uniprotkb:P97875 intact:EBI-8458873|intact:MINT-4428023|ensembl:ENSMUSP00000019882 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 psi-mi:rpb9_mouse(display_long)|uniprotkb:Polr2i(gene name)|psi-mi:Polr2i(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684308|imex:IM-28774-885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081535.1|ensembl:ENSMUSG00000019738(gene)|ensembl:ENSMUST00000019882(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P60898|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:69920(identity) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) - comment:mint|function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA10090 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rigid:eqVGkdjs8fTpIEDQbL6gRrteuhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y242 uniprotkb:Q8N653 intact:EBI-7413767|intact:MINT-8162425|uniprotkb:Q9UBH7|uniprotkb:Q0EFA8|uniprotkb:B0UY11|uniprotkb:Q5SQ89|uniprotkb:Q5STD6|intact:MINT-8247619|uniprotkb:Q9BUM2|uniprotkb:Q5STF5|uniprotkb:Q15967|uniprotkb:Q13176|uniprotkb:A6NCT8|ensembl:ENSP00000365431|ensembl:ENSP00000365433 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:tcf19_human(display_long)|uniprotkb:TCF19(gene name)|psi-mi:TCF19(display_short)|uniprotkb:SC1(gene name synonym)|uniprotkb:Transcription factor SC1(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684460|imex:IM-28774-899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305837.1|refseq:NP_009040.2|refseq:NP_001070979.1|ensembl:ENSG00000137310(gene)|ensembl:ENST00000376255(transcript)|ensembl:ENST00000376257(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0046872"(metal ion binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR039095|interpro:IPR042803|entrezgene/locuslink:6941(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:h+iBC3ckn1akJJ2QSTF+0iVceHo9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:UUx/XVHJt6mH+JDnqpbzAuJN6+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:P70396 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-1801294|uniprotkb:O54876|uniprotkb:O54877|uniprotkb:O54878|uniprotkb:Q9JJ45|ensembl:ENSMUSP00000052559 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:dlx5_mouse(display_long)|uniprotkb:Dlx5(gene name)|psi-mi:Dlx5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684292|imex:IM-28774-1801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) refseq:NP_034186.2|refseq:NP_942151.1|ensembl:ENSMUSG00000029755(gene)|ensembl:ENSMUST00000052609(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043583"(ear development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060322"(head development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097376"(interneuron axon guidance)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR022135|entrezgene/locuslink:13395(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:kSp3Apm9yjs2wBtkVT3nQB3RPNU10090 rigid:kPyWv8zevjCZ5+8ed9iRj46XHwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:Q60925 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-26673677|ensembl:ENSMUSP00000079693|uniprotkb:Q8VCX3 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:dbp_mouse(display_long)|uniprotkb:Albumin D box-binding protein(gene name synonym)|uniprotkb:Albumin D-element-binding protein(gene name synonym)|uniprotkb:Dbp(gene name)|psi-mi:Dbp(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684284|imex:IM-28774-1799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) ensembl:ENSMUSG00000059824(gene)|ensembl:ENSMUST00000080885(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007623"(circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029830|interpro:IPR040223|refseq:NP_058670.2|entrezgene/locuslink:13170(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:lcwsGCIxlexVpSuZTjEuZDgymlA10090 rigid:TUimAXMRMVvGpcPO/968iV4Oyrk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:P53568 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-26666537|ensembl:ENSMUSP00000064963|ensembl:ENSMUSP00000118588 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:cebpg_mouse(display_long)|uniprotkb:Granulocyte colony-stimulating factor promoter element 1-binding protein(gene name synonym)|uniprotkb:Immunoglobulin enhancer-binding protein 1(gene name synonym)|uniprotkb:Cebpg(gene name)|psi-mi:Cebpg(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684276|imex:IM-28774-1797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSMUSG00000056216(gene)|ensembl:ENSMUST00000070191(transcript)|ensembl:ENSMUST00000130491(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_034014.1|entrezgene/locuslink:12611(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:Kl4vhpKHcGIVXh3W05HrerMTCs010090 rigid:HnmPFCKqkHxNUoARYSpR5zBPDIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:P53566 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-2644207|uniprotkb:Q91XB6|ensembl:ENSMUSP00000096129 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:cebpa_mouse(display_long)|uniprotkb:Cebpa(gene name)|psi-mi:Cebpa(display_short)|uniprotkb:Cebp(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684268|imex:IM-28774-883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) refseq:NP_031704.2|refseq:NP_001274443.1|refseq:NP_001274444.1|refseq:NP_001274450.1|ensembl:ENSMUSG00000034957(gene)|ensembl:ENSMUST00000042985(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P53566|reactome:R-MMU-9616222|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|dip:DIP-44054N|entrezgene/locuslink:12606(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:pGJ6XTpLySPEYPc9uYgeawD6WTk10090 rigid:3DYakG3bD5zxayfo/bP0wCTJEHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q13207 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-2853051|uniprotkb:Q16424|uniprotkb:Q7Z647|ensembl:ENSP00000240328 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:tbx2_human(display_long)|uniprotkb:TBX2(gene name)|psi-mi:TBX2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684452|imex:IM-28774-3535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_005985.3|ensembl:ENSG00000121068(gene)|ensembl:ENST00000240328(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007569"(cell aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060465"(pharynx development)|go:"GO:0060560"(developmental growth involved in morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0060596"(mammary placode formation)|go:"GO:0072105"(ureteric peristalsis)|go:"GO:0090398"(cellular senescence)|go:"GO:1901208"(negative regulation of heart looping)|go:"GO:1901211"(negative regulation of cardiac chamber formation)|go:"GO:1905222"(atrioventricular canal morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR002070(Transcription factor, Brachyury)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR022582|interpro:IPR036960|go:"GO:1905072"(cardiac jelly development)|entrezgene/locuslink:6909(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:r5HgwtlqAyKL7wBI2lrjj/uhqMo9606 rigid:Mn4+KCcNq0Q5lBkMdfak2jt1is0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q15544 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-1027005|uniprotkb:Q9UHS0|uniprotkb:B2R8R3|ensembl:ENSP00000354633|uniprotkb:B4DY18 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:taf11_human(display_long)|uniprotkb:TAF11(gene name)|psi-mi:TAF11(display_short)|uniprotkb:TAF2I(gene name synonym)|uniprotkb:PRO2134(orf name)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit(gene name synonym)|uniprotkb:TFIID subunit p30-beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684444|imex:IM-28774-2241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_005634.1|ensembl:ENSG00000064995(gene)|ensembl:ENST00000361288(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|rcsb pdb:1BH8|rcsb pdb:1BH9|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|refseq:NP_001257417.1|dip:DIP-495N|entrezgene/locuslink:6882(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:bpvaKWTrUJbJ/klBA/j4DHYRbMg9606 rigid:klpgaB/E7ikEPwb3dXBgS2oXZMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P42224 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684436|imex:IM-28774-897 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N|entrezgene/locuslink:6772(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:EW8+RAfBdeBZCyiEsAp7L8E9j8I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:O60224 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-745513|uniprotkb:Q5JQZ0|uniprotkb:Q9UJU9|uniprotkb:B2RPE3|ensembl:ENSP00000469011|ensembl:ENSP00000469394|uniprotkb:A8MYD4|uniprotkb:Q3SYD4 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:ssx4_human(display_long)|uniprotkb:Cancer/testis antigen 5.4(gene name synonym)|uniprotkb:SSX4(gene name)|psi-mi:SSX4(display_short)|uniprotkb:SSX4B(gene name)|psi-mi:SSX4B(display_short)|uniprotkb:SSX4A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684428|imex:IM-28774-895 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_001030004.1|refseq:NP_005627.1|refseq:NP_783856.1|ensembl:ENSG00000268009(gene)|ensembl:ENSG00000269791(gene)|ensembl:ENST00000595235(transcript)|ensembl:ENST00000595689(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|refseq:NP_001035702.1|refseq:XP_016885102.1|refseq:XP_016885248.1|entrezgene/locuslink:6759(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:XHHJJoIvvSIjm/AO1gB1lYvXlHE9606 rigid:cLC1F43oj6qLE0jxUaO5a6WeYrA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q12772 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-465059|uniprotkb:Q86V36|uniprotkb:Q6GTH7|uniprotkb:Q9UH04|ensembl:ENSP00000354476|uniprotkb:Q05BD5 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:srbp2_human(display_long)|uniprotkb:SREBF2(gene name)|psi-mi:SREBF2(display_short)|uniprotkb:SREBP2(gene name synonym)|uniprotkb:Sterol regulatory element-binding transcription factor 2(gene name synonym)|uniprotkb:BHLHD2(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684420|imex:IM-28774-1807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) ensembl:ENSG00000198911(gene)|ensembl:ENST00000361204(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005829"(cytosol)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1UKL|reactome:R-HSA-1655829|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-9619665|refseq:NP_004590.2|dip:DIP-263N|entrezgene/locuslink:6721(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:OkTB/ZjBgPVLKu333KVw2AKrE5M9606 rigid:fa3u7JvzwnTTB/8IcWNZVnBota8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P23497 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684412|imex:IM-28774-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE|entrezgene/locuslink:6672(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rigid:adAUi0R0lCVjE2pUy+nmWC6IWxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P19388 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684404|imex:IM-28774-1353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N|entrezgene/locuslink:5434(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:TD/xQ5Qkon9ucliyh5eb6LqU4Wg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P30876 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684396|imex:IM-28774-1351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N|entrezgene/locuslink:5431(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:fms3BOz2ONVhtj6sAtDQRFnxG3g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q9P2R6 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-948076|uniprotkb:O43393|uniprotkb:O75046|uniprotkb:O75359|uniprotkb:Q5VXL9|uniprotkb:Q6P6B9|uniprotkb:Q9Y2W4|ensembl:ENSP00000338629|ensembl:ENSP00000383700 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:rere_human(display_long)|uniprotkb:Atrophin-1-related protein(gene name synonym)|uniprotkb:Atrophin-1-like protein(gene name synonym)|uniprotkb:RERE(gene name)|psi-mi:RERE(display_short)|uniprotkb:ARG(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:ATN1L(gene name synonym)|uniprotkb:KIAA0458(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684388|imex:IM-28774-893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_001036146.1|refseq:NP_001036147.1|refseq:NP_036234.3|refseq:XP_005263521.1|refseq:XP_016856847.1|refseq:XP_016856848.1|dip:DIP-47606N|ensembl:ENSG00000142599(gene)|ensembl:ENST00000337907(transcript)|ensembl:ENST00000400908(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|mint:Q9P2R6|rcsb pdb:2YQK|entrezgene/locuslink:473(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:fryo3nxpHdcexG2dqy00t0n4Nlw9606 rigid:+8lUMvgEITBa0yFO2scTl8jmebM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q9P2R6 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-948076|uniprotkb:O43393|uniprotkb:O75046|uniprotkb:O75359|uniprotkb:Q5VXL9|uniprotkb:Q6P6B9|uniprotkb:Q9Y2W4|ensembl:ENSP00000338629|ensembl:ENSP00000383700 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:rere_human(display_long)|uniprotkb:Atrophin-1-related protein(gene name synonym)|uniprotkb:Atrophin-1-like protein(gene name synonym)|uniprotkb:RERE(gene name)|psi-mi:RERE(display_short)|uniprotkb:ARG(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:ATN1L(gene name synonym)|uniprotkb:KIAA0458(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684380|imex:IM-28774-891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_001036146.1|refseq:NP_001036147.1|refseq:NP_036234.3|refseq:XP_005263521.1|refseq:XP_016856847.1|refseq:XP_016856848.1|dip:DIP-47606N|ensembl:ENSG00000142599(gene)|ensembl:ENST00000337907(transcript)|ensembl:ENST00000400908(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|mint:Q9P2R6|rcsb pdb:2YQK|entrezgene/locuslink:473(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:fryo3nxpHdcexG2dqy00t0n4Nlw9606 rigid:+8lUMvgEITBa0yFO2scTl8jmebM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P10244 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-1389468|uniprotkb:B2RBS5|uniprotkb:B7Z8D9|uniprotkb:F8W6N6|uniprotkb:Q53F07|ensembl:ENSP00000217026 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:mybb_human(display_long)|uniprotkb:Myb-like protein 2(gene name synonym)|uniprotkb:MYBL2(gene name)|psi-mi:MYBL2(display_short)|uniprotkb:BMYB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684372|imex:IM-28774-1805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_001265539.1|refseq:NP_002457.1|ensembl:ENSG00000101057(gene)|ensembl:ENST00000217026(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|mint:P10244|rcsb pdb:6C48|reactome:R-HSA-1362300|reactome:R-HSA-156711|reactome:R-HSA-8869496|entrezgene/locuslink:4605(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:2ldntN2B+u1fHcK4WPkL9UZYbzs9606 rigid:96FXUnvZFlw5nREGmp1UlKd982w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P25205 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684364|imex:IM-28774-2675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N|entrezgene/locuslink:4172(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:GYNLeqa2/l7D5xKk+VhED2j1gK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P14317 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684356|imex:IM-28774-1349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606 rigid:qF8gHSIKoLrdIdzji+OTTbyNiSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:P09874 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684348|imex:IM-28774-889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N|entrezgene/locuslink:142(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rigid:k+8qnvlke+EaiIPsvVDXUlN6NL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48552 uniprotkb:P10827 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 intact:EBI-286285|uniprotkb:P21205|uniprotkb:Q8N6A1|uniprotkb:Q96H73|uniprotkb:A8K3B5|ensembl:ENSP00000264637|ensembl:ENSP00000377679 psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:tha_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:EAR7(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:ERBA1(gene name synonym)|uniprotkb:NR1A1(gene name synonym)|uniprotkb:THRA1(gene name synonym)|uniprotkb:THRA2(gene name synonym)|uniprotkb:V-erbA-related protein 7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684340|imex:IM-28774-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N|entrezgene/locuslink:8204(identity) refseq:NP_001177847.1|refseq:NP_001177848.1|refseq:NP_003241.2|refseq:NP_955366.1|dip:DIP-31452N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1NAV|rcsb pdb:2H77|rcsb pdb:2H79|rcsb pdb:3HZF|rcsb pdb:3ILZ|rcsb pdb:3JZB|rcsb pdb:4LNW|rcsb pdb:4LNX|reactome:R-HSA-383280|reactome:R-HSA-4090294|ensembl:ENSG00000126351(gene)|ensembl:ENST00000264637(transcript)|ensembl:ENST00000394121(transcript)|entrezgene/locuslink:7067(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rogid:u1B3u6XbEyC3OKOWr25s9qZYe4o9606 rigid:gQ5fKPaqzIgjgAoFXO+2pvuRBSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:P48552 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684332|imex:IM-28774-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N|entrezgene/locuslink:8204(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rigid:/1ne/KhBTaQgsvoaSGo7TaMQO+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3UNW5 uniprotkb:Q9ERA0 intact:EBI-5691372|uniprotkb:Q99PF2|uniprotkb:Q14AW3|ensembl:ENSMUSP00000027629 intact:EBI-5717242|uniprotkb:Q3UGJ4|uniprotkb:Q8VC13|ensembl:ENSMUSP00000155683 psi-mi:tf2l1_mouse(display_long)|uniprotkb:Tfcp2l1(gene name)|psi-mi:Tfcp2l1(display_short)|uniprotkb:CP2-related transcriptional repressor 1(gene name synonym)|uniprotkb:Crtr1(gene name synonym)|uniprotkb:Tcfcp2l1(gene name synonym) psi-mi:tfcp2_mouse(display_long)|uniprotkb:Tfcp2(gene name)|psi-mi:Tfcp2(display_short)|uniprotkb:Tcfcp2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684324|imex:IM-28774-887 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076244.2|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007431"(salivary gland development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0045927"(positive regulation of growth)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037598|interpro:IPR041418|mint:Q3UNW5|ensembl:ENSMUSG00000026380(gene)|ensembl:ENSMUST00000027629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|entrezgene/locuslink:81879(identity) refseq:NP_258437.1|refseq:NP_001276532.1|ensembl:ENSMUSG00000009733(gene)|ensembl:ENSMUST00000229696(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|entrezgene/locuslink:21422(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:QtzNiWQU27XK2s0idF91/IAVi0E10090 rogid:j4vZiWTHCBOSFrA13f9zwO7bwuE10090 rigid:f9CdDdE0oCKlE5fqd+oEx57vRfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:Q99NE9 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-26672772|ensembl:ENSMUSP00000080219|uniprotkb:Q8CFL2|uniprotkb:Q99NE8 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:pbx4_mouse(display_long)|uniprotkb:Homeobox protein PBX4(gene name synonym)|uniprotkb:Pbx4(gene name)|psi-mi:Pbx4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684316|imex:IM-28774-3079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) ensembl:ENSMUSG00000031860(gene)|ensembl:ENSMUST00000081503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|refseq:NP_001020125.1|refseq:XP_006509865.1|refseq:XP_006509866.1|entrezgene/locuslink:80720(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:Ej1TAvVGooiYRb2qw+k+/ej1GQ810090 rigid:ZG+Q71crsHVksPtJRKSFUhXMc1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:O70137 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-26684233|ensembl:ENSMUSP00000014747 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:alx3_mouse(display_long)|uniprotkb:Proline-rich transcription factor ALX3(gene name synonym)|uniprotkb:Alx3(gene name)|psi-mi:Alx3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684260|imex:IM-28774-881 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) ensembl:ENSMUSG00000014603(gene)|ensembl:ENSMUST00000014747(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR033211|refseq:NP_031467.1|entrezgene/locuslink:11694(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:QK1opoUJyBXs+tyjHvBxhSgaiYs10090 rigid:+Dh8XZUzSRuj70byx9YxEMnKVi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0G7 uniprotkb:Q9Z0G7 intact:EBI-16732462|ensembl:ENSMUSP00000057466 intact:EBI-16732462|ensembl:ENSMUSP00000057466 psi-mi:zbt22_mouse(display_long)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Zbtb22(gene name)|psi-mi:Zbtb22(display_short)|uniprotkb:Bing1(gene name synonym)|uniprotkb:Zfp297(gene name synonym)|uniprotkb:Znf297(gene name synonym) psi-mi:zbt22_mouse(display_long)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Zbtb22(gene name)|psi-mi:Zbtb22(display_short)|uniprotkb:Bing1(gene name synonym)|uniprotkb:Zfp297(gene name synonym)|uniprotkb:Znf297(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684217|imex:IM-28774-3531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000051390(gene)|ensembl:ENSMUST00000053429(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|refseq:NP_065650.1|entrezgene/locuslink:81630(identity) ensembl:ENSMUSG00000051390(gene)|ensembl:ENSMUST00000053429(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|interpro:IPR000210(BTB/POZ-like)|refseq:NP_065650.1|entrezgene/locuslink:81630(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZUg4jLqKYHyBigBV0SXAd5XM6YY10090 rogid:ZUg4jLqKYHyBigBV0SXAd5XM6YY10090 rigid:2COlUBHb9bmP7VGrc7yy6I27sto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EST8 uniprotkb:Q9WTK5 intact:EBI-10107924|uniprotkb:Q3TVL7|uniprotkb:Q3TWK9|uniprotkb:Q3U8Y9|uniprotkb:Q3UCI2|uniprotkb:Q3URP0|uniprotkb:Q3UW99|uniprotkb:Q5NT97|uniprotkb:Q99NA4|ensembl:ENSMUSP00000041173|ensembl:ENSMUSP00000110102 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 psi-mi:ikbz_mouse(display_long)|uniprotkb:Nfkbiz(gene name)|psi-mi:Nfkbiz(display_short)|uniprotkb:Inap(gene name synonym)|uniprotkb:Mail(gene name synonym)|uniprotkb:I-kappa-B-zeta(gene name synonym)|uniprotkb:IL-1 inducible nuclear ankyrin-repeat protein(gene name synonym)|uniprotkb:Molecule possessing ankyrin repeats induced by lipopolysaccharide(gene name synonym) psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684209|imex:IM-28774-3529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152866.1|refseq:NP_001152867.1|refseq:NP_085115.1|ensembl:ENSMUSG00000035356(gene)|ensembl:ENSMUST00000036273(transcript)|ensembl:ENSMUST00000114458(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006954"(inflammatory response)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|entrezgene/locuslink:80859(identity) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6|entrezgene/locuslink:18034(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bIB4d6wCJvSWQ3hMLYfaKVlxCKQ10090 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 rigid:S0aGgMBmY6P528k9cjZFHM2AQMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EST8 uniprotkb:P25799 intact:EBI-10107924|uniprotkb:Q3TVL7|uniprotkb:Q3TWK9|uniprotkb:Q3U8Y9|uniprotkb:Q3UCI2|uniprotkb:Q3URP0|uniprotkb:Q3UW99|uniprotkb:Q5NT97|uniprotkb:Q99NA4|ensembl:ENSMUSP00000041173|ensembl:ENSMUSP00000110102 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:ikbz_mouse(display_long)|uniprotkb:Nfkbiz(gene name)|psi-mi:Nfkbiz(display_short)|uniprotkb:Inap(gene name synonym)|uniprotkb:Mail(gene name synonym)|uniprotkb:I-kappa-B-zeta(gene name synonym)|uniprotkb:IL-1 inducible nuclear ankyrin-repeat protein(gene name synonym)|uniprotkb:Molecule possessing ankyrin repeats induced by lipopolysaccharide(gene name synonym) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684201|imex:IM-28774-2673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152866.1|refseq:NP_001152867.1|refseq:NP_085115.1|ensembl:ENSMUSG00000035356(gene)|ensembl:ENSMUST00000036273(transcript)|ensembl:ENSMUST00000114458(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006954"(inflammatory response)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|entrezgene/locuslink:80859(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|entrezgene/locuslink:18033(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bIB4d6wCJvSWQ3hMLYfaKVlxCKQ10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 rigid:kZLkpQTg3Us3Z2MaJM45F/95cvk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EST8 uniprotkb:O88522 intact:EBI-10107924|uniprotkb:Q3TVL7|uniprotkb:Q3TWK9|uniprotkb:Q3U8Y9|uniprotkb:Q3UCI2|uniprotkb:Q3URP0|uniprotkb:Q3UW99|uniprotkb:Q5NT97|uniprotkb:Q99NA4|ensembl:ENSMUSP00000041173|ensembl:ENSMUSP00000110102 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 psi-mi:ikbz_mouse(display_long)|uniprotkb:Nfkbiz(gene name)|psi-mi:Nfkbiz(display_short)|uniprotkb:Inap(gene name synonym)|uniprotkb:Mail(gene name synonym)|uniprotkb:I-kappa-B-zeta(gene name synonym)|uniprotkb:IL-1 inducible nuclear ankyrin-repeat protein(gene name synonym)|uniprotkb:Molecule possessing ankyrin repeats induced by lipopolysaccharide(gene name synonym) psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684193|imex:IM-28774-2239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152866.1|refseq:NP_001152867.1|refseq:NP_085115.1|ensembl:ENSMUSG00000035356(gene)|ensembl:ENSMUST00000036273(transcript)|ensembl:ENSMUST00000114458(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006954"(inflammatory response)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|entrezgene/locuslink:80859(identity) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bIB4d6wCJvSWQ3hMLYfaKVlxCKQ10090 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rigid:ZgmsStppwFmjCk+oS3q89cXyl0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EST8 uniprotkb:Q8VDK3 intact:EBI-10107924|uniprotkb:Q3TVL7|uniprotkb:Q3TWK9|uniprotkb:Q3U8Y9|uniprotkb:Q3UCI2|uniprotkb:Q3URP0|uniprotkb:Q3UW99|uniprotkb:Q5NT97|uniprotkb:Q99NA4|ensembl:ENSMUSP00000041173|ensembl:ENSMUSP00000110102 intact:EBI-26684150|ensembl:ENSMUSP00000028609|ensembl:ENSMUSP00000126941|ensembl:ENSMUSP00000131940|uniprotkb:Q921H5|uniprotkb:Q9Z2K6 psi-mi:ikbz_mouse(display_long)|uniprotkb:Nfkbiz(gene name)|psi-mi:Nfkbiz(display_short)|uniprotkb:Inap(gene name synonym)|uniprotkb:Mail(gene name synonym)|uniprotkb:I-kappa-B-zeta(gene name synonym)|uniprotkb:IL-1 inducible nuclear ankyrin-repeat protein(gene name synonym)|uniprotkb:Molecule possessing ankyrin repeats induced by lipopolysaccharide(gene name synonym) psi-mi:elf5_mouse(display_long)|uniprotkb:E74-like factor 5(gene name synonym)|uniprotkb:Elf5(gene name)|psi-mi:Elf5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684185|imex:IM-28774-2671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152866.1|refseq:NP_001152867.1|refseq:NP_085115.1|ensembl:ENSMUSG00000035356(gene)|ensembl:ENSMUST00000036273(transcript)|ensembl:ENSMUST00000114458(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006954"(inflammatory response)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|entrezgene/locuslink:80859(identity) ensembl:ENSMUSG00000027186(gene)|ensembl:ENSMUST00000028609(transcript)|ensembl:ENSMUST00000164172(transcript)|ensembl:ENSMUST00000171693(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007398"(ectoderm development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033069|interpro:IPR036388|interpro:IPR036390|refseq:NP_001139285.1|refseq:NP_034255.2|refseq:XP_006498768.1|entrezgene/locuslink:13711(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bIB4d6wCJvSWQ3hMLYfaKVlxCKQ10090 rogid:N7BsFPqKqtcRRv9NTCaZBE+yns010090 rigid:eaWf+LUqJOKHzEGRKdez07vwJBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EST8 uniprotkb:O70273 intact:EBI-10107924|uniprotkb:Q3TVL7|uniprotkb:Q3TWK9|uniprotkb:Q3U8Y9|uniprotkb:Q3UCI2|uniprotkb:Q3URP0|uniprotkb:Q3UW99|uniprotkb:Q5NT97|uniprotkb:Q99NA4|ensembl:ENSMUSP00000041173|ensembl:ENSMUSP00000110102 intact:EBI-26684102|ensembl:ENSMUSP00000087961|ensembl:ENSMUSP00000106805|uniprotkb:Q922E8|uniprotkb:Q922T6|uniprotkb:Q99K12 psi-mi:ikbz_mouse(display_long)|uniprotkb:Nfkbiz(gene name)|psi-mi:Nfkbiz(display_short)|uniprotkb:Inap(gene name synonym)|uniprotkb:Mail(gene name synonym)|uniprotkb:I-kappa-B-zeta(gene name synonym)|uniprotkb:IL-1 inducible nuclear ankyrin-repeat protein(gene name synonym)|uniprotkb:Molecule possessing ankyrin repeats induced by lipopolysaccharide(gene name synonym) psi-mi:ehf_mouse(display_long)|uniprotkb:ETS domain-containing transcription factor(gene name synonym)|uniprotkb:Ehf(gene name)|psi-mi:Ehf(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684142|imex:IM-28774-3527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152866.1|refseq:NP_001152867.1|refseq:NP_085115.1|ensembl:ENSMUSG00000035356(gene)|ensembl:ENSMUST00000036273(transcript)|ensembl:ENSMUST00000114458(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006954"(inflammatory response)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:2000321"(positive regulation of T-helper 17 cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|entrezgene/locuslink:80859(identity) ensembl:ENSMUSG00000012350(gene)|ensembl:ENSMUST00000090475(transcript)|ensembl:ENSMUST00000111174(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050673"(epithelial cell proliferation)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033071|interpro:IPR036388|interpro:IPR036390|refseq:NP_031940.1|refseq:XP_006498760.1|refseq:XP_006498761.1|refseq:XP_006498762.1|refseq:XP_006498763.1|refseq:XP_006498764.1|refseq:XP_006498765.1|entrezgene/locuslink:13661(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:bIB4d6wCJvSWQ3hMLYfaKVlxCKQ10090 rogid:XQMuKmdGtwNj/fjgVKNHo2CY4KQ10090 rigid:Xer9O/ghALMltV0uPjHIsnRkuaI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C0F3 uniprotkb:P16220 intact:EBI-8489702|uniprotkb:Q658I9|intact:MINT-8417741|intact:EBI-28979269|ensembl:ENSP00000313582|ensembl:ENSP00000363736|ensembl:ENSP00000489127|ensembl:ENSP00000489469 intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963 psi-mi:zn436_human(display_long)|uniprotkb:ZNF436(gene name)|psi-mi:ZNF436(display_short)|uniprotkb:KIAA1710(gene name synonym) psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684094|imex:IM-28774-2237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000313582|ensembl:ENSP00000363736|ensembl:ENSP00000489127|ensembl:ENSP00000489469|refseq:NP_085137.1|refseq:NP_001070663.1|ensembl:ENSG00000125945(gene)|ensembl:ENSG00000283009(gene)|ensembl:ENST00000314011(transcript)|ensembl:ENST00000374608(transcript)|ensembl:ENST00000635349(transcript)|ensembl:ENST00000635400(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9C0F3|reactome:R-HSA-212436|entrezgene/locuslink:80818(identity) go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|entrezgene/locuslink:1385(identity) - comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:5JtFfuD2eB5eIPCz0ykuQllFr4s9606 rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606 rigid:SkPbHWLtNacSOJIR3Ng5saZw1BI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BT49 uniprotkb:P51610 intact:EBI-741350|ensembl:ENSP00000215742|ensembl:ENSP00000382084|uniprotkb:B2RD97|uniprotkb:D3DX40 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:thap7_human(display_long)|uniprotkb:THAP7(gene name)|psi-mi:THAP7(display_short) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684086|imex:IM-28774-2235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008695.1|refseq:NP_085050.2|ensembl:ENSG00000184436(gene)|ensembl:ENST00000215742(transcript)|ensembl:ENST00000399133(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0106153"(phosphorylated histone binding)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026519|entrezgene/locuslink:80764(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|entrezgene/locuslink:3054(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4efYWbkvlRsynamdao3y6gVxhtA9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:1Z2gWX4gMHiiJLWGxorEE56I10g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99MD8 uniprotkb:P48379 intact:EBI-26684046|ensembl:ENSMUSP00000141951|uniprotkb:Q6P1G7|uniprotkb:Q8BT55|uniprotkb:Q922I4|uniprotkb:Q9CSA0|uniprotkb:Q9CXJ8 intact:EBI-3043952|ensembl:ENSMUSP00000002444|uniprotkb:Q8BXR3 psi-mi:mynn_mouse(display_long)|uniprotkb:Mynn(gene name)|psi-mi:Mynn(display_short) psi-mi:rfx2_mouse(display_long)|uniprotkb:Rfx2(gene name)|psi-mi:Rfx2(display_short)|uniprotkb:Regulatory factor X 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684078|imex:IM-28774-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000037730(gene)|ensembl:ENSMUST00000192715(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001276550.1|refseq:NP_001276551.1|refseq:NP_001276552.1|refseq:NP_085034.2|entrezgene/locuslink:80732(identity) ensembl:ENSMUSG00000024206(gene)|ensembl:ENSMUST00000002444(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001675"(acrosome assembly)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|refseq:NP_033082.1|refseq:NP_082063.1|entrezgene/locuslink:19725(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9EuCysx57GuGNCRQ32wfB1f83DE10090 rogid:1pdvERwU8gFjVZXQmwVm3HYiG0010090 rigid:cnBMYZCoX1aSmA1WJRVvL8LK2YA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99877 uniprotkb:Q01844 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684500|imex:IM-28774-1355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|entrezgene/locuslink:8341(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nGZETothwO57PuE11M5ogikaZkM9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:oSOEvJeJsj2PtpneEUJ0cCDsFp0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q8N653 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684484|imex:IM-28774-1809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:O0kA6mGL2I0DTm90hN3lmqr00Vs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q9Y473 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-3438881|uniprotkb:A8K9H2|ensembl:ENSP00000262259 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:zn175_human(display_long)|uniprotkb:ZNF175(gene name)|psi-mi:ZNF175(display_short)|uniprotkb:Zinc finger protein OTK18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684476|imex:IM-28774-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_009078.1|ensembl:ENSG00000105497(gene)|ensembl:ENST00000262259(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|entrezgene/locuslink:7728(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:gX8TOVK1IXy/kyXo2P6F9J6yqKU9606 rigid:khd5yVWVN6F5ZX0E2Xn7IAWbj8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q92481 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-725275|uniprotkb:Q5JYX6|uniprotkb:Q9NQ63|uniprotkb:Q9NU99|uniprotkb:Q9UJI7|uniprotkb:Q9Y214|uniprotkb:Q9Y3K3|ensembl:ENSP00000377265 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:ap2b_human(display_long)|uniprotkb:Activating enhancer-binding protein 2-beta(gene name synonym)|uniprotkb:TFAP2B(gene name)|psi-mi:TFAP2B(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684468|imex:IM-28774-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) refseq:NP_003212.2|refseq:XP_011513139.1|ensembl:ENST00000393655(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0097276"(cellular creatinine homeostasis)|go:"GO:0097277"(cellular urea homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008122(Transcription factor AP-2 beta, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|reactome:R-HSA-3232118|reactome:R-HSA-8866904|reactome:R-HSA-8866907|reactome:R-HSA-8866910|go:"GO:0010842"(retina layer formation)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043588"(skin development)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055062"(phosphate ion homeostasis)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072210"(metanephric nephron development)|go:"GO:0097070"(ductus arteriosus closure)|go:"GO:0097275"(cellular ammonium homeostasis)|ensembl:ENSG00000008196(gene)|entrezgene/locuslink:7021(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:nD3C+YodBUsGSz1Ggw2nVaQMsJQ9606 rigid:uY7mzk4hHz2LknrjgiTYPz1mZYI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97875 uniprotkb:P97368 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 intact:EBI-925694|uniprotkb:Q149R5|uniprotkb:Q99L81|ensembl:ENSMUSP00000002495 psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:meis3_mouse(display_long)|uniprotkb:Meis3(gene name)|psi-mi:Meis3(display_short)|uniprotkb:Mrg2(gene name synonym)|uniprotkb:Meis1-related protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684300|imex:IM-28774-1803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) refseq:NP_032653.2|refseq:NP_001289401.1|refseq:XP_006539666.1|refseq:NP_001264917.1|refseq:NP_001264918.1|ensembl:ENSMUSG00000041420(gene)|ensembl:ENSMUST00000002495(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|entrezgene/locuslink:17537(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rogid:Yu1LnYMFa21iCQS6XzlUkJQYkAM10090 rigid:XIpn/U1EQj+/JPxspClzros/mfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:Q9JKN5 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-1213712|ensembl:ENSMUSP00000061408 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:olig1_mouse(display_long)|uniprotkb:Olig1(gene name)|psi-mi:Olig1(display_short)|uniprotkb:Oligodendrocyte-specific bHLH transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684572|imex:IM-28774-3539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) refseq:NP_058664.2|ensembl:ENSMUSG00000046160(gene)|ensembl:ENSMUST00000056882(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q9JKN5|entrezgene/locuslink:50914(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:1R93ekMg/uZq5unF9PJGlf/iiJ810090 rigid:z+z/jMOfkbiMcr4LnsvGGAnE29w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:Q9QXV3 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-17168105|uniprotkb:B2RWH0|uniprotkb:Q9QUP8|uniprotkb:Q9QXV4|uniprotkb:Q9QZX3|ensembl:ENSMUSP00000062593 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:ing1_mouse(display_long)|uniprotkb:Ing1(gene name)|psi-mi:Ing1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684564|imex:IM-28774-1811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) refseq:NP_001289386.1|refseq:NP_001289387.1|refseq:NP_001289388.1|refseq:NP_001289389.1|refseq:NP_036049.2|ensembl:ENSMUSG00000045969(gene)|ensembl:ENSMUST00000054399(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010941"(regulation of cell death)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028643|interpro:IPR028651|entrezgene/locuslink:26356(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:3aDQK3WQG3fc2NbP/mjWCtg5fFk10090 rigid:UWxnpVdQCM8ogZcN7mv/750Dwog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:Q9WTP9 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-26674907|ensembl:ENSMUSP00000035976 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:vax2_mouse(display_long)|uniprotkb:Ventral retina homeodomain protein(gene name synonym)|uniprotkb:Vax2(gene name)|psi-mi:Vax2(display_short)|uniprotkb:Vex(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684556|imex:IM-28774-1357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) ensembl:ENSMUSG00000034777(gene)|ensembl:ENSMUST00000037807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033021|go:"GO:0043010"(camera-type eye development)|refseq:NP_036042.1|entrezgene/locuslink:24113(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:gyaEel7JgrCB8jlzkvFdzD+fZBU10090 rigid:AcTSq/scf7cCivzk7jUBgX/sHMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:A2AQR4 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-26673603|ensembl:ENSMUSP00000085285 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:a2aqr4_mouse(display_long)|uniprotkb:Zfp64(gene name)|psi-mi:Zfp64(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684548|imex:IM-28774-2245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) ensembl:ENSMUSG00000027551(gene)|ensembl:ENSMUST00000087971(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_033590.2|entrezgene/locuslink:22722(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:zzFaR9hgXdPiH+QNw8QFmUi0A9s10090 rigid:3WeRvagoAKqSItDcsp160Fk1zn0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:Q04742 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-26668713|ensembl:ENSMUSP00000046026|uniprotkb:Q3SXG0 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:emx1_mouse(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:Emx1(gene name)|psi-mi:Emx1(display_short)|uniprotkb:Emx-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684508|imex:IM-28774-3537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) ensembl:ENSMUSG00000033726(gene)|ensembl:ENSMUST00000045942(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021537"(telencephalon development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_034261.1|entrezgene/locuslink:13796(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:LMDuhE7sn1jB0oE9LCCdJxgL2l410090 rigid:XG8ZzLcsS3eE2QRAFavSL0ec+n0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:O54943 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-1266779|uniprotkb:O54954 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684532|imex:IM-28774-2243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H|entrezgene/locuslink:18627(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 rigid:B12qrdJIatLkQVApZ0MyJNXnu1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:O88621 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-7457430|intact:MINT-4998752|uniprotkb:Q9QZL5|uniprotkb:Q9R241|ensembl:ENSMUSP00000036591 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:foxh1_mouse(display_long)|uniprotkb:Foxh1(gene name)|psi-mi:Foxh1(display_short)|uniprotkb:Fast1(gene name synonym)|uniprotkb:Fast2(gene name synonym)|uniprotkb:Forkhead activin signal transducer 1(gene name synonym)|uniprotkb:Forkhead activin signal transducer 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684524|imex:IM-28774-3081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) refseq:NP_032015.1|refseq:XP_006520499.1|ensembl:ENSMUSG00000033837(gene)|ensembl:ENSMUST00000037824(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:O88621|reactome:R-MMU-1181150|reactome:R-MMU-1502540|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048318"(axial mesoderm development)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|entrezgene/locuslink:14106(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint function:"Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element)"|comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:/wralkUfGdtYTuVGaOKelphRTTc10090 rigid:OggYPZOUhnlnt/la/2F3F+IxH2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:P43136 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-4319956|uniprotkb:Q61504|uniprotkb:Q922G8|ensembl:ENSMUSP00000002466 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:nr2f6_mouse(display_long)|uniprotkb:Nr2f6(gene name)|psi-mi:Nr2f6(display_short)|uniprotkb:Ear-2(gene name synonym)|uniprotkb:Ear2(gene name synonym)|uniprotkb:Erbal2(gene name synonym)|uniprotkb:COUP transcription factor 3(gene name synonym)|uniprotkb:V-erbA-related protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684516|imex:IM-28774-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) refseq:NP_034280.2|ensembl:ENSMUSG00000002393(gene)|ensembl:ENSMUST00000002466(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048666"(neuron development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|reactome:R-MMU-383280|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:13864(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:6DWUUJLWerd0u2lgGNGhP32T1gQ10090 rigid:wUeMFFmoI6f8EqSESG2NBFIZbSw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:P22361 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-5272860|uniprotkb:E9QP86|ensembl:ENSMUSP00000031535 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:hnf1a_mouse(display_long)|uniprotkb:Hnf1a(gene name)|psi-mi:Hnf1a(display_short)|uniprotkb:Hnf-1(gene name synonym)|uniprotkb:Hnf-1a(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:Liver-specific transcription factor LF-B1(gene name synonym)|uniprotkb:Transcription factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684540|imex:IM-28774-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) refseq:NP_033353.2|ensembl:ENSMUSG00000029556(gene)|ensembl:ENSMUST00000031535(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001824"(blastocyst development)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008104"(protein localization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016573"(histone acetylation)|go:"GO:0030073"(insulin secretion)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035623"(renal glucose absorption)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045453"(bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048608"(reproductive structure development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR001356(Homeobox)|interpro:IPR006897(Hepatocyte nuclear factor 1, beta isoform, C-terminal)|interpro:IPR006898(Hepatocyte nuclear factor 1, alpha isoform C-terminal)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR023219|interpro:IPR039066|mint:P22361|rcsb pdb:1F93|rcsb pdb:1G2Y|rcsb pdb:1G2Z|rcsb pdb:1G39|rcsb pdb:1JB6|go:"GO:0045120"(pronucleus)|entrezgene/locuslink:21405(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:RU8cTEgDUX13LBGIHa7hxUIkojc10090 rigid:jHsSsT8xm5mSeRs0vDT5BtdCpy0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:O43251 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684933|imex:IM-28774-2685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:1ZcMBTN6FQ7YD+cPS3zxOX+ax34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:P63157 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-26681110|ensembl:ENSMUSP00000053147|ensembl:ENSMUSP00000109478|ensembl:ENSMUSP00000109480|uniprotkb:Q9JK26 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:barh1_mouse(display_long)|uniprotkb:Bar-class homeodomain protein MBH2(gene name synonym)|uniprotkb:BarH-related homeobox protein 1(gene name synonym)|uniprotkb:Barhl1(gene name)|psi-mi:Barhl1(display_short)|uniprotkb:Bhx1(gene name synonym)|uniprotkb:Mbh2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684581|imex:IM-28774-3083 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) ensembl:ENSMUSG00000026805(gene)|ensembl:ENSMUST00000050776(transcript)|ensembl:ENSMUST00000113847(transcript)|ensembl:ENSMUST00000113849(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030901"(midbrain development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR001356(Homeobox)|refseq:NP_001157658.1|refseq:NP_062319.1|refseq:XP_006498245.1|refseq:XP_006498246.1|refseq:XP_011237440.1|entrezgene/locuslink:54422(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:KNqv1fU+PSWeMxt9yR3hNanXBns10090 rigid:UYsE4UzkmtMqHpn6CWse/cr810Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BPY8 uniprotkb:P17482 intact:EBI-10295883|uniprotkb:Q96CI1|uniprotkb:A8K0Z2|uniprotkb:G3V294|uniprotkb:E9PB55|uniprotkb:Q8N0V6|ensembl:ENSP00000315198|ensembl:ENSP00000337330|ensembl:ENSP00000370654|ensembl:ENSP00000422175|ensembl:ENSP00000424101|ensembl:ENSP00000451794|ensembl:ENSP00000452003|ensembl:ENSP00000452098|ensembl:ENSP00000452340 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:hop_human(display_long)|uniprotkb:HOPX(gene name)|psi-mi:HOPX(display_short)|uniprotkb:HOD(gene name synonym)|uniprotkb:HOP(gene name synonym)|uniprotkb:LAGY(gene name synonym)|uniprotkb:Lung cancer-associated Y protein(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Not expressed in choriocarcinoma protein 1(gene name synonym)|uniprotkb:OB1(gene name synonym)|uniprotkb:Odd homeobox protein 1(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684917|imex:IM-28774-1377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138931.1|refseq:NP_001138932.1|refseq:NP_115884.4|refseq:NP_631957.1|refseq:NP_631958.1|ensembl:ENSG00000171476(gene)|ensembl:ENST00000317745(transcript)|ensembl:ENST00000337881(transcript)|ensembl:ENST00000381255(transcript)|ensembl:ENST00000503639(transcript)|ensembl:ENST00000508121(transcript)|ensembl:ENST00000553379(transcript)|ensembl:ENST00000555760(transcript)|ensembl:ENST00000556376(transcript)|ensembl:ENST00000556614(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003166"(bundle of His development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016575"(histone deacetylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039162|refseq:XP_016864218.1|refseq:XP_016864219.1|refseq:XP_016864220.1|refseq:XP_016864221.1|refseq:XP_016864222.1|refseq:XP_016864223.1|entrezgene/locuslink:84525(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/gi1nxWJWDhu+a3Lsjs+SORvACM9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:JpqFvZTcLJMdfbeiU0LTxxki3xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BPY8 uniprotkb:O43711 intact:EBI-10295883|uniprotkb:Q96CI1|uniprotkb:A8K0Z2|uniprotkb:G3V294|uniprotkb:E9PB55|uniprotkb:Q8N0V6|ensembl:ENSP00000315198|ensembl:ENSP00000337330|ensembl:ENSP00000370654|ensembl:ENSP00000422175|ensembl:ENSP00000424101|ensembl:ENSP00000451794|ensembl:ENSP00000452003|ensembl:ENSP00000452098|ensembl:ENSP00000452340 intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921 psi-mi:hop_human(display_long)|uniprotkb:HOPX(gene name)|psi-mi:HOPX(display_short)|uniprotkb:HOD(gene name synonym)|uniprotkb:HOP(gene name synonym)|uniprotkb:LAGY(gene name synonym)|uniprotkb:Lung cancer-associated Y protein(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Not expressed in choriocarcinoma protein 1(gene name synonym)|uniprotkb:OB1(gene name synonym)|uniprotkb:Odd homeobox protein 1(gene name synonym) psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684909|imex:IM-28774-3549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138931.1|refseq:NP_001138932.1|refseq:NP_115884.4|refseq:NP_631957.1|refseq:NP_631958.1|ensembl:ENSG00000171476(gene)|ensembl:ENST00000317745(transcript)|ensembl:ENST00000337881(transcript)|ensembl:ENST00000381255(transcript)|ensembl:ENST00000503639(transcript)|ensembl:ENST00000508121(transcript)|ensembl:ENST00000553379(transcript)|ensembl:ENST00000555760(transcript)|ensembl:ENST00000556376(transcript)|ensembl:ENST00000556614(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003166"(bundle of His development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016575"(histone deacetylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039162|refseq:XP_016864218.1|refseq:XP_016864219.1|refseq:XP_016864220.1|refseq:XP_016864221.1|refseq:XP_016864222.1|refseq:XP_016864223.1|entrezgene/locuslink:84525(identity) ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2|entrezgene/locuslink:30012(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/gi1nxWJWDhu+a3Lsjs+SORvACM9606 rogid:TTCEjERZEVADujEiNmARHuHEle49606 rigid:GN/hU/U1vP+BzuUAEgQquCcP2p0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JN0 uniprotkb:Q13363 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684901|imex:IM-28774-2255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|entrezgene/locuslink:84458(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|entrezgene/locuslink:1487(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:NUxKoTMXKKFOuwVXM6n7rGOcoYc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96JM7 uniprotkb:Q8N653 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684893|imex:IM-28774-911 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|entrezgene/locuslink:84456(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:IJycKLALuxJ5B/dRExnQ2HVmpJs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q15466 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-3910729|uniprotkb:Q5QP36|ensembl:ENSP00000254227|uniprotkb:F1D8P5 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:nr0b2_human(display_long)|uniprotkb:NR0B2(gene name)|psi-mi:NR0B2(display_short)|uniprotkb:SHP(gene name synonym)|uniprotkb:Orphan nuclear receptor SHP(gene name synonym)|uniprotkb:Small heterodimer partner(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684885|imex:IM-28774-909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_068804.1|ensembl:ENSG00000131910(gene)|ensembl:ENST00000254227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR033544|interpro:IPR035500|rcsb pdb:1YUC|rcsb pdb:2Q3Y|rcsb pdb:2Z4J|rcsb pdb:4DOR|rcsb pdb:4ONI|rcsb pdb:5UFS|rcsb pdb:6W9M|reactome:R-HSA-383280|dip:DIP-46313N|entrezgene/locuslink:8431(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:8ZFtFlZ1C0MKqn8Nyx9zMcOzH/g9606 rigid:6HteIZTs3lcQlhjsmofW1+EvWBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15466 uniprotkb:P55771 intact:EBI-3910729|uniprotkb:Q5QP36|ensembl:ENSP00000254227|uniprotkb:F1D8P5 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:nr0b2_human(display_long)|uniprotkb:NR0B2(gene name)|psi-mi:NR0B2(display_short)|uniprotkb:SHP(gene name synonym)|uniprotkb:Orphan nuclear receptor SHP(gene name synonym)|uniprotkb:Small heterodimer partner(gene name synonym) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684877|imex:IM-28774-2683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068804.1|ensembl:ENSG00000131910(gene)|ensembl:ENST00000254227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR033544|interpro:IPR035500|rcsb pdb:1YUC|rcsb pdb:2Q3Y|rcsb pdb:2Z4J|rcsb pdb:4DOR|rcsb pdb:4ONI|rcsb pdb:5UFS|rcsb pdb:6W9M|reactome:R-HSA-383280|dip:DIP-46313N|entrezgene/locuslink:8431(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:8ZFtFlZ1C0MKqn8Nyx9zMcOzH/g9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:WZTTtux2F0zQDbAHt891Uw8LIug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NF99 uniprotkb:Q9NWS9 intact:EBI-10213894|uniprotkb:Q9BRM2|ensembl:ENSP00000331577 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 psi-mi:zn397_human(display_long)|uniprotkb:ZNF397(gene name)|psi-mi:ZNF397(display_short)|uniprotkb:ZNF47(gene name synonym)|uniprotkb:ZSCAN15(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 47(gene name synonym) psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684869|imex:IM-28774-907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128650.1|refseq:NP_115723.1|refseq:XP_011524533.1|ensembl:ENSG00000186812(gene)|ensembl:ENST00000330501(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016881531.1|entrezgene/locuslink:84307(identity) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX7xHkDe7vA0VsT2f+MnIivEXU9606 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rigid:Ul4vgC+vV3vhQelvAcd9220jFoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NF99 uniprotkb:Q9NWS9 intact:EBI-10213894|uniprotkb:Q9BRM2|ensembl:ENSP00000331577 intact:EBI-3925851|ensembl:ENSP00000472802|uniprotkb:Q96AF5|intact:EBI-11955977 psi-mi:zn397_human(display_long)|uniprotkb:ZNF397(gene name)|psi-mi:ZNF397(display_short)|uniprotkb:ZNF47(gene name synonym)|uniprotkb:ZSCAN15(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 47(gene name synonym) psi-mi:zn446_human(display_long)|uniprotkb:ZNF446(gene name)|psi-mi:ZNF446(display_short)|uniprotkb:ZKSCAN20(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 20(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684861|imex:IM-28774-2681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128650.1|refseq:NP_115723.1|refseq:XP_011524533.1|ensembl:ENSG00000186812(gene)|ensembl:ENST00000330501(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016881531.1|entrezgene/locuslink:84307(identity) refseq:NP_060378.1|ensembl:ENSG00000083838(gene)|ensembl:ENST00000594369(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027768|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_005259109.1|entrezgene/locuslink:55663(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX7xHkDe7vA0VsT2f+MnIivEXU9606 rogid:OmdWsFX7XvcMP2KC6KCLCyUuTe89606 rigid:Ul4vgC+vV3vhQelvAcd9220jFoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NF99 uniprotkb:P57086 intact:EBI-10213894|uniprotkb:Q9BRM2|ensembl:ENSP00000331577 intact:EBI-745846|uniprotkb:Q6IAG7|ensembl:ENSP00000301995|ensembl:ENSP00000363103|ensembl:ENSP00000481289 psi-mi:zn397_human(display_long)|uniprotkb:ZNF397(gene name)|psi-mi:ZNF397(display_short)|uniprotkb:ZNF47(gene name synonym)|uniprotkb:ZSCAN15(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 47(gene name synonym) psi-mi:scnd1_human(display_long)|uniprotkb:SCAND1(gene name)|psi-mi:SCAND1(display_short)|uniprotkb:SDP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684853|imex:IM-28774-2253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128650.1|refseq:NP_115723.1|refseq:XP_011524533.1|ensembl:ENSG00000186812(gene)|ensembl:ENST00000330501(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_016881531.1|entrezgene/locuslink:84307(identity) refseq:NP_057642.1|ensembl:ENSG00000171222(gene)|ensembl:ENST00000305978(transcript)|ensembl:ENST00000373991(transcript)|ensembl:ENST00000615116(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269|refseq:NP_361012.2|entrezgene/locuslink:51282(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4VX7xHkDe7vA0VsT2f+MnIivEXU9606 rogid:PYwugMdd/3klI5aAelQle8pGoMQ9606 rigid:ykNKEVsZsnB9st4kgevJNoQPuY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9Y6 uniprotkb:Q8N653 intact:EBI-355441|uniprotkb:Q6ZRR2|uniprotkb:Q9H9D3|uniprotkb:Q585T5|uniprotkb:B7Z6Y7|uniprotkb:B7Z823|uniprotkb:F5GZX4|uniprotkb:F8W898|uniprotkb:Q2TAM4|ensembl:ENSP00000263331 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:rpa2_human(display_long)|uniprotkb:POLR1B(gene name)|psi-mi:POLR1B(display_short)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684845|imex:IM-28774-3547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001131076.1|refseq:NP_061887.2|refseq:NP_001269703.1|refseq:NP_001269705.1|refseq:NP_001269706.1|refseq:NP_001269708.1|refseq:NP_001269701.1|dip:DIP-27538N|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q9H9Y6|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|ensembl:ENSG00000125630(gene)|ensembl:ENST00000263331(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0007566"(embryo implantation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0014029"(neural crest formation)|go:"GO:0017126"(nucleologenesis)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|entrezgene/locuslink:84172(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:enAJckjxEU6bE3J3OA5pFREXC3U9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:BS1BxH2xGNUYkAB7OiBBTGrtHZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H1I8 uniprotkb:Q9H0N5 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684837|imex:IM-28774-905 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1|entrezgene/locuslink:84164(identity) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rigid:ZM60RFnHvqJLIT+Krl3/hm69VQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BYE7 uniprotkb:O75177 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684829|imex:IM-28774-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|entrezgene/locuslink:84108(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:96Me+UYiKHaiYj0TbUjpRor4sM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q99459 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684821|imex:IM-28774-3099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N|entrezgene/locuslink:988(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 rigid:xl2znTKl0PlqnhrZdFXfhWy/A90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:O94880 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-2680164|uniprotkb:B4DI82|uniprotkb:A7MCZ3|ensembl:ENSP00000385795 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:phf14_human(display_long)|uniprotkb:KIAA0783(gene name synonym)|uniprotkb:PHF14(gene name)|psi-mi:PHF14(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684813|imex:IM-28774-3097 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_055475.2|ensembl:ENSG00000106443(gene)|ensembl:ENST00000403050(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O94880|entrezgene/locuslink:9678(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:5x6w7H9UP9mf4xk3lXYfAHaIo2Q9606 rigid:9oJkd78zppOefxL5ZID0UpBS3NQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:O43513 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684805|imex:IM-28774-3545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:AqvdUYnpoynScATva8GCUngxv88 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q13503 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684797|imex:IM-28774-3095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N|entrezgene/locuslink:9412(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rigid:wMxZ9yuweBBR6xSQ/dSBJq1xAUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q06455 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-743342|uniprotkb:O14784|uniprotkb:Q06456|uniprotkb:Q14873|uniprotkb:Q16239|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q6IBL1|uniprotkb:Q92479|uniprotkb:Q9BRZ0|ensembl:ENSP00000265814|ensembl:ENSP00000428543|ensembl:ENSP00000481112|ensembl:ENSP00000481315|ensembl:ENSP00000481799|uniprotkb:B7Z4P4|uniprotkb:E7EPN4|uniprotkb:Q6NXH1|uniprotkb:Q7Z4J5 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:mtg8_human(display_long)|uniprotkb:Protein MTG8(gene name synonym)|uniprotkb:Protein ETO(gene name synonym)|uniprotkb:Eight twenty one protein(gene name synonym)|uniprotkb:Cyclin-D-related protein(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 2(gene name synonym)|uniprotkb:RUNX1T1(gene name)|psi-mi:RUNX1T1(display_short)|uniprotkb:AML1T1(gene name synonym)|uniprotkb:CBFA2T1(gene name synonym)|uniprotkb:CDR(gene name synonym)|uniprotkb:ETO(gene name synonym)|uniprotkb:MTG8(gene name synonym)|uniprotkb:ZMYND2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684789|imex:IM-28774-2251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_001185554.1|refseq:NP_001185555.1|refseq:NP_001185556.1|refseq:NP_001185557.1|refseq:NP_001185558.1|refseq:NP_001185559.1|refseq:NP_001185560.1|refseq:NP_001185561.1|refseq:NP_004340.1|refseq:NP_783552.1|refseq:NP_783553.1|refseq:NP_783554.1|ensembl:ENSG00000079102(gene)|ensembl:ENST00000265814(transcript)|ensembl:ENST00000523629(transcript)|ensembl:ENST00000613302(transcript)|ensembl:ENST00000614812(transcript)|ensembl:ENST00000617740(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|refseq:XP_011515653.1|refseq:XP_011515654.1|refseq:XP_011515655.1|interpro:IPR013290("Myeloid transforming gene on chromosome 8 (MTG8)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|mint:Q06455|rcsb pdb:1WQ6|rcsb pdb:2DJ8|rcsb pdb:2H7B|rcsb pdb:2KNH|rcsb pdb:2KYG|rcsb pdb:2OD1|rcsb pdb:2ODD|rcsb pdb:2PP4|rcsb pdb:4JOL|refseq:NP_001185563.1|refseq:NP_001185562.1|refseq:NP_001185608.1|refseq:XP_006716739.1|refseq:XP_016869420.1|refseq:XP_016869421.1|refseq:XP_016869422.1|refseq:XP_016869423.1|refseq:XP_016869424.1|refseq:XP_016869425.1|refseq:XP_016869426.1|dip:DIP-29401N|entrezgene/locuslink:862(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:SMomKOZSbtqhKiAkkUkabKbC8/09606 rigid:1/BMFhEcsR5eIQXfQiey6Kc7V7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q9H0N5 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684781|imex:IM-28774-1375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rigid:QyLwarfrJoXIQPRFMtCjJMq/xBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q16559 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-10237959|uniprotkb:A0AVI7|ensembl:ENSP00000334547 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:tal2_human(display_long)|uniprotkb:TAL2(gene name)|psi-mi:TAL2(display_short)|uniprotkb:BHLHA19(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684773|imex:IM-28774-1373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_005412.1|ensembl:ENSG00000186051(gene)|ensembl:ENST00000334077(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|entrezgene/locuslink:6887(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:JgO8ZFHP9X70qLk3jzH1SbU+xiU9606 rigid:uwRXmOwmeWUFPBmBBnzqQ2zozkI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:P40763 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684765|imex:IM-28774-1371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N|entrezgene/locuslink:6774(identity) - - crc64:6C00632211C8012D figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:5BNgYnoU0ECA0N13TBVwzkn51+g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:O60225 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-10186198|uniprotkb:Q5JQ59|uniprotkb:Q96AW3|uniprotkb:Q5JQ60|ensembl:ENSP00000290558 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:ssx5_human(display_long)|uniprotkb:SSX5(gene name)|psi-mi:SSX5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684757|imex:IM-28774-1369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_066295.3|refseq:NP_783729.1|refseq:XP_016885247.1|refseq:XP_011542251.1|ensembl:ENSG00000165583(gene)|ensembl:ENST00000347757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:6758(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:sVINA7fZyttxJg58NXmqzVL9PAc9606 rigid:23/7CqvyBMlzHMth7BYbzgIocRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q9BS16 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-6871750|ensembl:ENSP00000242872|ensembl:ENSP00000379911|ensembl:ENSP00000422421|uniprotkb:Q9H4L0 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:cenpk_human(display_long)|uniprotkb:Protein AF-5alpha(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:FKSG14(orf name)|uniprotkb:ICEN37(gene name synonym)|uniprotkb:Interphase centromere complex protein 37(gene name synonym)|uniprotkb:CENPK(gene name)|psi-mi:CENPK(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684749|imex:IM-28774-903 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:XP_011541838.1|refseq:XP_016865179.1|refseq:XP_016865180.1|refseq:XP_016865181.1|ensembl:ENSG00000123219(gene)|ensembl:ENST00000242872(transcript)|ensembl:ENST00000396679(transcript)|ensembl:ENST00000514814(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR020993|mint:Q9BS16|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001253967.1|refseq:NP_071428.2|entrezgene/locuslink:64105(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:853vdRxBjPdA2x4j4UKmZjBYhVY9606 rigid:yRwPqM2Ts8A+3rjSaJBigKS+GxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q9HCC6 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-2680288|uniprotkb:Q5SVA5|ensembl:ENSP00000304595 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:hes4_human(display_long)|uniprotkb:BHLHB42(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:Hairy and enhancer of split 4(gene name synonym)|uniprotkb:bHLH factor Hes4(gene name synonym)|uniprotkb:HES4(gene name)|psi-mi:HES4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684741|imex:IM-28774-1819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_001135939.1|refseq:NP_066993.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000188290(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|ensembl:ENST00000304952(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0000785"(chromatin)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|entrezgene/locuslink:57801(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:OHv5KLK08PgjwZIwpFRchPSBdAA9606 rigid:FcCEOw1YJa1MCioSSbzHdUeBmao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q96AQ6 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684733|imex:IM-28774-3093 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N|entrezgene/locuslink:57326(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 rigid:lFSdIYbkxACSZTJASkOHWia5LCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:P29590 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684725|imex:IM-28774-3091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:GDPZmzhMwANpj04yVArNkKan5AU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:P61457 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684717|imex:IM-28774-3089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:rbyB4Yl95FLss/aK5rca9KlCr3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:P61457 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684709|imex:IM-28774-2679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:rbyB4Yl95FLss/aK5rca9KlCr3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q9Y2W7 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684701|imex:IM-28774-1367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894|entrezgene/locuslink:30818(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606 rigid:GUOJkM7JS/bp+0gRAZeWAtfy0+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q92994 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-949861|ensembl:ENSP00000448387|uniprotkb:Q13223|uniprotkb:Q5PR24|uniprotkb:Q6IQ02|uniprotkb:Q9HCW6|uniprotkb:Q9HCW7|uniprotkb:Q9HCW8|uniprotkb:Q3SYD9|uniprotkb:Q96KX3|uniprotkb:B4DIG5|uniprotkb:B3KU36|uniprotkb:B7Z2N3|uniprotkb:F5H5Z7|uniprotkb:F8WA46 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:tf3b_human(display_long)|uniprotkb:B-related factor 1(gene name synonym)|uniprotkb:TATA box-binding protein-associated factor, RNA polymerase III, subunit 2(gene name synonym)|uniprotkb:BRF1(gene name)|psi-mi:BRF1(display_short)|uniprotkb:BRF(gene name synonym)|uniprotkb:GTF3B(gene name synonym)|uniprotkb:TAF3B2(gene name synonym)|uniprotkb:TAF3C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684693|imex:IM-28774-1817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) go:"GO:0005654"(nucleoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009304"(tRNA transcription)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046872"(metal ion binding)|go:"GO:0070897"(transcription preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR011665(Brf1-like TBP-binding)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR029529|interpro:IPR036915|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|ensembl:ENSG00000185024(gene)|ensembl:ENST00000547530(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_001229715.1|refseq:NP_001229716.1|refseq:NP_001229717.1|refseq:NP_001229718.1|refseq:NP_001510.2|refseq:NP_663718.1|refseq:NP_001229719.1|refseq:XP_005267620.1|entrezgene/locuslink:2972(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:89DaAP5RNWeXBVWz3IGSJjm+Txo9606 rigid:siy+zWxx7ql15xt+KKoeWfoqDZk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:P29083 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684685|imex:IM-28774-3543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:ZUf517JWWTH6mEmTUwe0Z1REjSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q9NPJ6 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684677|imex:IM-28774-901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:4EIZV1k76yICAag0mnQTiLSDURU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q9NY61 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684669|imex:IM-28774-3087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|entrezgene/locuslink:26574(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:ce3+abL0jNelmaj2pLpXr4xI4so false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q8IU81 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-6115514|uniprotkb:Q53EL7|uniprotkb:Q6DC95|uniprotkb:Q9BRZ9|uniprotkb:Q9Y4P4|ensembl:ENSP00000307265 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:i2bp1_human(display_long)|uniprotkb:IRF2BP1(gene name)|psi-mi:IRF2BP1(display_short)|uniprotkb:Probable E3 ubiquitin-protein ligase IRF2BP1(gene name synonym)|uniprotkb:Probable RING-type E3 ubiquitin transferase IRF2BP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684661|imex:IM-28774-1815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_056464.1|ensembl:ENSG00000170604(gene)|ensembl:ENST00000302165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR018957|interpro:IPR022750|interpro:IPR044882|mint:Q8IU81|entrezgene/locuslink:26145(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:0ooWsKsxvLQtWbTA3FsVfO+6TBA9606 rigid:7oymjhXapAP3OmiyVaSd4ygeoSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q8IYH5 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684653|imex:IM-28774-1365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:4AR8F5uxWpFUCtOWIklwmzfAhc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q13573 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684645|imex:IM-28774-2249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N|entrezgene/locuslink:22938(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 rigid:UdFwddiq8RyLMtwDYatF2ow28WE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13901 uniprotkb:Q9H0N5 intact:EBI-3844053|uniprotkb:A8K336|uniprotkb:D6W5F8|uniprotkb:Q05D64|ensembl:ENSP00000348107|ensembl:ENSP00000386468|ensembl:ENSP00000386779 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 psi-mi:c1d_human(display_long)|uniprotkb:C1D(gene name)|psi-mi:C1D(display_short) psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684637|imex:IM-28774-1363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177192.1|refseq:NP_001177194.1|refseq:NP_006324.1|refseq:NP_775269.1|ensembl:ENSG00000197223(gene)|ensembl:ENST00000355848(transcript)|ensembl:ENST00000409302(transcript)|ensembl:ENST00000410067(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|mint:Q13901|reactome:R-HSA-6791226|entrezgene/locuslink:10438(identity) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HewHUZfde5bSlgFrz+EdepfFCgk9606 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rigid:B88CJ5xP1eqXyrxX7NYp8iUJJ9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q99909 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-10295431|uniprotkb:O60223|uniprotkb:Q9BRW7|uniprotkb:Q5JQZ3|ensembl:ENSP00000298396 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:ssx3_human(display_long)|uniprotkb:SSX3(gene name)|psi-mi:SSX3(display_short)|uniprotkb:Cancer/testis antigen 5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684629|imex:IM-28774-3085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_066294.1|refseq:XP_011542187.1|ensembl:ENSG00000165584(gene)|ensembl:ENST00000298396(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:10214(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:jSB31TCCfnAP7jshF00a7bTb/sA9606 rigid:T0lncUhe3yJ3U4XU4ppsmi+7ayA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0N5 uniprotkb:Q13111 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684621|imex:IM-28774-3541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|entrezgene/locuslink:10036(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:uGLNJoAU7UlvCDgGqMtDL+4lIls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:V9GX74 uniprotkb:O55144 intact:EBI-26678042|ensembl:ENSMUSP00000139017 intact:EBI-26667147|ensembl:ENSMUSP00000047457|uniprotkb:Q5SQB4 psi-mi:v9gx74_mouse(display_long)|uniprotkb:Trps1(gene name)|psi-mi:Trps1(display_short) psi-mi:tlx3_mouse(display_long)|uniprotkb:Homeobox TLX-3(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)|uniprotkb:Respiratory neuron homeobox protein(gene name synonym)|uniprotkb:Tlx3(gene name)|psi-mi:Tlx3(display_short)|uniprotkb:Hox11l2(gene name synonym)|uniprotkb:Rnx(gene name synonym)|uniprotkb:Tlx1l2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684613|imex:IM-28774-1361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038679(gene)|ensembl:ENSMUST00000183757(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028440|interpro:IPR036236|refseq:NP_001297410.1|entrezgene/locuslink:83925(identity) ensembl:ENSMUSG00000040610(gene)|ensembl:ENSMUST00000037746(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|go:"GO:0007417"(central nervous system development)|refseq:NP_064300.2|entrezgene/locuslink:27140(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Q9XRWPP7QOn3QLX9iIQaJc4uejE10090 rogid:d/V6L0gHTUP1gzLNuKrEJzwE4w810090 rigid:NPLh31JG13/JGHmxroK0w/uwr0w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:V9GX74 uniprotkb:Q05BA5 intact:EBI-26678042|ensembl:ENSMUSP00000139017 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:v9gx74_mouse(display_long)|uniprotkb:Trps1(gene name)|psi-mi:Trps1(display_short) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684605|imex:IM-28774-1813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038679(gene)|ensembl:ENSMUST00000183757(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028440|interpro:IPR036236|refseq:NP_001297410.1|entrezgene/locuslink:83925(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Q9XRWPP7QOn3QLX9iIQaJc4uejE10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:lBJI7wTL1QcoenFBslhHDj5YFHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:V9GX74 uniprotkb:Q61545 intact:EBI-26678042|ensembl:ENSMUSP00000139017 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:v9gx74_mouse(display_long)|uniprotkb:Trps1(gene name)|psi-mi:Trps1(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684597|imex:IM-28774-2247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038679(gene)|ensembl:ENSMUST00000183757(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028440|interpro:IPR036236|refseq:NP_001297410.1|entrezgene/locuslink:83925(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Q9XRWPP7QOn3QLX9iIQaJc4uejE10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:YSAiDz7X4XgysAOHktkvzdmOHBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99PM3 uniprotkb:Q9D2H6 intact:EBI-7640185|ensembl:ENSMUSP00000021345|uniprotkb:Q8C812|intact:MINT-1348159 intact:EBI-26674949|uniprotkb:Q6A0E1 psi-mi:tf2aa_mouse(display_long)|uniprotkb:Gtf2a1(gene name)|psi-mi:Gtf2a1(display_short)|uniprotkb:General transcription factor IIA subunit 1(gene name synonym) psi-mi:sp2_mouse(display_long)|uniprotkb:Sp2(gene name)|psi-mi:Sp2(display_short)|uniprotkb:Kiaa0048(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684589|imex:IM-28774-1359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020962(gene)|ensembl:ENSMUST00000021345(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-9018519|refseq:NP_113568.2|refseq:NP_780544.1|entrezgene/locuslink:83602(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0072359"(circulatory system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:NP_001074433.1|refseq:NP_084496.2|interpro:IPR030451|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|entrezgene/locuslink:78912(identity) - function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity|comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:1XALkG2DyhbEvv9NPBHJqlfg+b010090 rogid:UcPZ7bur3a/CDkDAeAP1GvD5Pvg10090 rigid:7jvEe/A2Ng56eXwJFdigppu5+ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:O43251 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684925|imex:IM-28774-2257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1|entrezgene/locuslink:23543(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:1ZcMBTN6FQ7YD+cPS3zxOX+ax34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:Q16533 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-11915024|ensembl:ENSP00000216294 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:snpc1_human(display_long)|uniprotkb:SNAPC1(gene name)|psi-mi:SNAPC1(display_short)|uniprotkb:Proximal sequence element-binding transcription factor subunit gamma(gene name synonym)|uniprotkb:SNAP43(gene name synonym)|uniprotkb:Small nuclear RNA-activating complex polypeptide 1(gene name synonym)|uniprotkb:snRNA-activating protein complex 43 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684973|imex:IM-28774-3551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) ensembl:ENSG00000023608(gene)|ensembl:ENST00000216294(transcript)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019185"(snRNA-activating protein complex)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR019188|reactome:R-HSA-6807505|reactome:R-HSA-749476|reactome:R-HSA-76071|refseq:NP_003073.1|dip:DIP-504N|entrezgene/locuslink:6617(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:xXCySYpmgoo2VmzFtT1iRFFUkj49606 rigid:KqDV+Il9HRIJgylGbBQUe4YTX8Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:P05423 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684965|imex:IM-28774-2689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:LGjc6x7tpa2iM0u2BUJgKgkEjCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:Q9Y2Y4 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-954098|ensembl:ENSP00000376035|ensembl:ENSP00000262630|uniprotkb:Q8WVP2 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:zbt32_human(display_long)|uniprotkb:Fanconi anemia zinc finger protein(gene name synonym)|uniprotkb:Testis zinc finger protein(gene name synonym)|uniprotkb:FANCC-interacting protein(gene name synonym)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)|uniprotkb:FAZF(gene name synonym)|uniprotkb:TZFP(gene name synonym)|uniprotkb:ZNF538(gene name synonym)|uniprotkb:Zinc finger protein 538(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684941|imex:IM-28774-2259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) ensembl:ENST00000262630(transcript)|ensembl:ENST00000392197(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:3M5B|ensembl:ENSG00000011590(gene)|refseq:NP_055198.1|refseq:NP_001303831.1|refseq:NP_001303832.1|refseq:XP_011525020.1|refseq:XP_016882078.1|entrezgene/locuslink:27033(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:gAas4U/RF96mVnqIK9dlhZ55zEY9606 rigid:lWw9vDfoPok+QM4ZDnnsNiN1+9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:P31276 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-2293590|uniprotkb:Q5BL02|uniprotkb:Q96J32|uniprotkb:Q9NR24|uniprotkb:Q9NYD5|ensembl:ENSP00000243056 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:hxc13_human(display_long)|uniprotkb:HOXC13(gene name)|psi-mi:HOXC13(display_short)|uniprotkb:HOX3G(gene name synonym)|uniprotkb:Homeobox protein Hox-3G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684949|imex:IM-28774-913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) refseq:NP_059106.2|ensembl:ENSG00000123364(gene)|ensembl:ENST00000243056(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|entrezgene/locuslink:3229(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:sGnVE8V9ZSPBuUnE8vdLLosrIa49606 rigid:VSaqOZOt5e3+h7Z/w/nTDYevGh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:Q16633 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-943588|uniprotkb:Q14983|uniprotkb:B2R8Z9|ensembl:ENSP00000376786 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:obf1_human(display_long)|uniprotkb:POU2AF1(gene name)|psi-mi:POU2AF1(display_short)|uniprotkb:OBF1(gene name synonym)|uniprotkb:B-cell-specific coactivator OBF-1(gene name synonym)|uniprotkb:OCT-binding factor 1(gene name synonym)|uniprotkb:BOB-1(gene name synonym)|uniprotkb:OCA-B(gene name synonym)|uniprotkb:BOB1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684957|imex:IM-28774-2687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) refseq:NP_006226.2|ensembl:ENSG00000110777(gene)|ensembl:ENST00000393067(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006959"(humoral immune response)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098586"(cellular response to virus)|interpro:IPR015389(POU, class 2, associating factor 1)|rcsb pdb:1CQT|entrezgene/locuslink:5450(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:HWFixMtrq10Dfpmkh86TqryeWjc9606 rigid:9KruW88jGlNbaraP4+aBKVGmKEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P78317 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-2340927|uniprotkb:Q49AR8|uniprotkb:B2R6D6|uniprotkb:D6RF58|intact:EBI-28970119|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:rnf4_human(display_long)|uniprotkb:SNURF(gene name synonym)|uniprotkb:RING finger protein 4(gene name synonym)|uniprotkb:Small nuclear ring finger protein(gene name synonym)|uniprotkb:RNF4(gene name)|psi-mi:RNF4(display_short)|uniprotkb:RES4-26(orf name)|uniprotkb:RING-type E3 ubiquitin transferase RNF4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685181|imex:IM-28774-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_001171938.1|refseq:NP_001171939.1|refseq:NP_002929.1|ensembl:ENSP00000315212|ensembl:ENSP00000424076|ensembl:ENSP00000426503|ensembl:ENST00000511859|ensembl:ENSP00000426615|ensembl:ENST00000541204|ensembl:ENSP00000446369|ensembl:ENSG00000063978(gene)|ensembl:ENST00000314289(transcript)|ensembl:ENST00000506706(transcript)|ensembl:ENST00000511600(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090234"(regulation of kinetochore assembly)|go:"GO:1990752"(microtubule end)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR043295|mint:P78317|rcsb pdb:2EA6|rcsb pdb:2XEU|rcsb pdb:4PPE|reactome:R-HSA-5693607|reactome:R-HSA-983168|entrezgene/locuslink:6047(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:Yhu2iAaNQYcfGdYohDPBdhMFEpc9606 rigid:78taBudszIsgO8l672Wjlhz2H/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:Q9BQY4 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684989|imex:IM-28774-1821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rigid:mFb26oxetsHw6ehJX48dHIUS+T4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:O43513 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685005|imex:IM-28774-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:Z6Sw9r2x87j1DXeil93o16eXyKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75446 uniprotkb:P61457 intact:EBI-632609|uniprotkb:D3DP38|ensembl:ENSP00000296504 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:sap30_human(display_long)|uniprotkb:30 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30(gene name synonym)|uniprotkb:SAP30(gene name)|psi-mi:SAP30(display_short)|uniprotkb:Sin3-associated polypeptide p30(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685349|imex:IM-28774-3109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003855.1|ensembl:ENSG00000164105(gene)|ensembl:ENST00000296504(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|mint:O75446|rcsb pdb:2KDP|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|dip:DIP-33328N|entrezgene/locuslink:8819(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:w113AyekZAZr9VOJWcWEFIhqBYA9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:guP46hopLW5Ol3CVbf8FMK4d1Wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75446 uniprotkb:Q02535 intact:EBI-632609|uniprotkb:D3DP38|ensembl:ENSP00000296504 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:sap30_human(display_long)|uniprotkb:30 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30(gene name synonym)|uniprotkb:SAP30(gene name)|psi-mi:SAP30(display_short)|uniprotkb:Sin3-associated polypeptide p30(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685341|imex:IM-28774-1385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003855.1|ensembl:ENSG00000164105(gene)|ensembl:ENST00000296504(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|mint:O75446|rcsb pdb:2KDP|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|dip:DIP-33328N|entrezgene/locuslink:8819(identity) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:w113AyekZAZr9VOJWcWEFIhqBYA9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rigid:K+X8oD52JyU1wBJ/dhE+60d2ae0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15164 uniprotkb:P15407 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685333|imex:IM-28774-3557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|entrezgene/locuslink:8805(identity) refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N|entrezgene/locuslink:8061(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606 rigid:WK6rYUqqUQdYzkmkkuDeQ/U3Sm4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15164 uniprotkb:P42226 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685325|imex:IM-28774-2277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|entrezgene/locuslink:8805(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:MIrXAt0i5D8hYvhMOIMoMRFixt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15164 uniprotkb:Q16236 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2007911|uniprotkb:Q53RW6|uniprotkb:Q59HH2|uniprotkb:Q96F71|uniprotkb:B2RBU2|uniprotkb:B4E338|uniprotkb:E9PGJ7|intact:EBI-28978278|ensembl:ENSP00000380252 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:nf2l2_human(display_long)|uniprotkb:NFE2L2(gene name)|psi-mi:NFE2L2(display_short)|uniprotkb:NRF2(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)|uniprotkb:HEBP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685317|imex:IM-28774-2275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|entrezgene/locuslink:8805(identity) ensembl:ENSP00000380252|ensembl:ENST00000397063|ensembl:ENSP00000380253|ensembl:ENST00000446151|ensembl:ENSP00000411575|ensembl:ENST00000464747|ensembl:ENSP00000467401|refseq:NP_001300829.1|refseq:NP_001300830.1|refseq:NP_001138884.1|refseq:NP_006155.2|refseq:NP_001138885.1|dip:DIP-29971N|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029845|mint:Q16236|rcsb pdb:2FLU|rcsb pdb:2LZ1|rcsb pdb:3ZGC|rcsb pdb:4IFL|rcsb pdb:5WFV|rcsb pdb:6T7V|reactome:R-HSA-8932339|reactome:R-HSA-9707587|reactome:R-HSA-9707616|ensembl:ENSG00000116044(gene)|ensembl:ENST00000397062(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035690"|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046223"(aflatoxin catabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|entrezgene/locuslink:4780(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:EjSeL1dJClhC2vIPip6QDc8QAUk9606 rigid:BuCM1oYvt9LCeyrwQYg1bszAYfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15164 uniprotkb:P18848 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685309|imex:IM-28774-1845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|entrezgene/locuslink:8805(identity) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity) - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rigid:Nc18F5LukTeJoyM4aOzfXL1Tp78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75530 uniprotkb:Q92800 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685301|imex:IM-28774-1843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|entrezgene/locuslink:8726(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|entrezgene/locuslink:2145(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rigid:Co7RV4siZu0LJ14GZZRJwZlISNg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H3D4 uniprotkb:Q04741 intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731 intact:EBI-26568770|ensembl:ENSP00000258106|uniprotkb:Q0D2P0|uniprotkb:Q53T30|uniprotkb:Q86XB0 psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym) psi-mi:emx1_human(display_long)|uniprotkb:Empty spiracles homolog 1(gene name synonym)|uniprotkb:Empty spiracles-like protein 1(gene name synonym)|uniprotkb:EMX1(gene name)|psi-mi:EMX1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685293|imex:IM-28774-2273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|entrezgene/locuslink:8626(identity) ensembl:ENSG00000135638(gene)|ensembl:ENST00000258106(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042493"|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|mint:Q04741|refseq:NP_004088.2|refseq:XP_011530999.1|entrezgene/locuslink:2016(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/06/18 rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606 rogid:1JOu5FpZmRUuMUKzFVgHWAPd4Ns9606 rigid:S5L0pZhJh39krGGx0J03wKVp93k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14593 uniprotkb:P48382 intact:EBI-1057665|uniprotkb:O95839|uniprotkb:Q6FGA8|uniprotkb:Q24JQ1|ensembl:ENSP00000305071|ensembl:ENSP00000384572 intact:EBI-923266|uniprotkb:Q5VWC3|uniprotkb:D3DV19|uniprotkb:B7Z848|uniprotkb:E9PFU4|ensembl:ENSP00000290524|ensembl:ENSP00000357864|ensembl:ENSP00000389130 psi-mi:rfxk_human(display_long)|uniprotkb:RFXANK(gene name)|psi-mi:RFXANK(display_short)|uniprotkb:ANKRA1(gene name synonym)|uniprotkb:RFXB(gene name synonym)|uniprotkb:Regulatory factor X subunit B(gene name synonym)|uniprotkb:Regulatory factor X-associated ankyrin-containing protein(gene name synonym)|uniprotkb:Ankyrin repeat family A protein 1(gene name synonym) psi-mi:rfx5_human(display_long)|uniprotkb:RFX5(gene name)|psi-mi:RFX5(display_short)|uniprotkb:Regulatory factor X 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685285|imex:IM-28774-3555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003712.1|refseq:NP_604389.1|refseq:NP_001265656.1|refseq:NP_001265657.1|refseq:XP_005260191.1|refseq:XP_005260192.1|refseq:XP_016882904.1|refseq:XP_016882905.1|ensembl:ENSG00000064490(gene)|ensembl:ENST00000303088(transcript)|ensembl:ENST00000407360(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017362(DNA-binding, RFXANK)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:3UXG|rcsb pdb:3V30|rcsb pdb:6MEW|entrezgene/locuslink:8625(identity) refseq:NP_000440.1|refseq:NP_001020774.1|refseq:XP_005245462.1|refseq:XP_005245463.1|refseq:XP_011508149.1|refseq:XP_011508150.1|refseq:XP_011508151.1|refseq:XP_011508152.1|ensembl:ENSG00000143390(gene)|ensembl:ENST00000290524(transcript)|ensembl:ENST00000368870(transcript)|ensembl:ENST00000452671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR029298|interpro:IPR033486|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|interpro:IPR040889|mint:P48382|rcsb pdb:2KW3|rcsb pdb:3V30|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|entrezgene/locuslink:5993(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:MepZW2vO+tBA4f1UGh979gzgY9g9606 rogid:kElLakR+ct4K8Mw6q91im3K8Zh89606 rigid:4PIgjt48I+cZcgvx13rmIf0q4pk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y265 uniprotkb:Q8N653 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685277|imex:IM-28774-1383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N|entrezgene/locuslink:8607(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:h5mM0IJLJDlpULT7bUdButTx1Lw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H2G9 uniprotkb:P14317 intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4 intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176 psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym) psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685269|imex:IM-28774-1381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity) ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606 rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606 rigid:I3aXe/O6woCaBX38rAC8UF6AP9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H2G9 uniprotkb:Q01844 intact:EBI-2548012|intact:EBI-28986503|ensembl:ENSP00000327541|ensembl:ENSP00000356782|uniprotkb:O15298|uniprotkb:Q5T531|uniprotkb:Q5T533|uniprotkb:Q9GZX4 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:go45_human(display_long)|uniprotkb:BLZF1(gene name)|psi-mi:BLZF1(display_short)|uniprotkb:JEM1(gene name synonym)|uniprotkb:Basic leucine zipper nuclear factor 1(gene name synonym)|uniprotkb:JEM-1(gene name synonym)|uniprotkb:p45 basic leucine-zipper nuclear factor(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685261|imex:IM-28774-1841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508394.1|ensembl:ENSG00000117475(gene)|ensembl:ENST00000329281(transcript)|ensembl:ENST00000367808(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR013183(Protein of unknown function DUF1721, fungi)|interpro:IPR027095|mint:Q9H2G9|reactome:R-HSA-162658|refseq:NP_003657.1|ensembl:ENSP00000327541|ensembl:ENST00000367807|ensembl:ENSP00000356781|ensembl:ENSP00000356782|refseq:NP_001307901.1|refseq:NP_001307902.1|entrezgene/locuslink:8548(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:FqMAghbeSRbqLmtaKELM5JZ+H3s9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:KAMDF+WyMKo77Yd2Xddndp5XaKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C035 uniprotkb:Q8N653 intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685253|imex:IM-28774-1839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300|entrezgene/locuslink:85363(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:NM4063xYzinwbRJd/xscOcD3wu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C035 uniprotkb:P61457 intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685245|imex:IM-28774-2271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300|entrezgene/locuslink:85363(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:bjPLUHsGEcmaPdy0heWYc/JV4io false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C035 uniprotkb:Q01844 intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685237|imex:IM-28774-2697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300|entrezgene/locuslink:85363(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:7D+ZDKAL908yVIjAHmr5iLXFj+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:Q9Y6K9 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685221|imex:IM-28774-2269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:Q4o2oSR5VutLcccePiBjDSERIpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:Q8N653 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685213|imex:IM-28774-3105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:koSM7YZIn90YwEvPnxmYUnyExBc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:Q15633 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685205|imex:IM-28774-1837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:YQ/0fygFrJK0pi+l6opRgboBIPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:Q15545 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685197|imex:IM-28774-3103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:6879(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rigid:RcTLkk60N1RiyyyEVBMdciqDrWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:O00267 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685189|imex:IM-28774-2267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:zajr9J7e8fBww6kOlJfxm67D9xM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQY4 uniprotkb:Q9H9S0 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 intact:EBI-20993792|ensembl:ENSP00000229307|uniprotkb:D3DUU4|uniprotkb:Q2TTG0|uniprotkb:Q6JZS5 psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:nanog_human(display_long)|uniprotkb:Homeobox transcription factor Nanog(gene name synonym)|uniprotkb:NANOG(gene name)|psi-mi:NANOG(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26684981|imex:IM-28774-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity) ensembl:ENSG00000111704(gene)|ensembl:ENST00000229307(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|rcsb pdb:2KT0|rcsb pdb:4RBO|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-452723|reactome:R-HSA-6785807|refseq:NP_001284627.1|refseq:NP_079141.2|entrezgene/locuslink:79923(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 rogid:S0YYjHcs+NsYDWsoTGakgFOWaxk9606 rigid:XvicyoRW5imGFrK7N1cCZYBUMEM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P19388 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685173|imex:IM-28774-1835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N|entrezgene/locuslink:5434(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:XJ3cf5LPoH/rwkaw5f/1HJVHA0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:O15514 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685165|imex:IM-28774-917 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N|entrezgene/locuslink:5433(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:EsfFPkS0ihKoqwUwDNW84CU3WZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P30876 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685157|imex:IM-28774-2695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N|entrezgene/locuslink:5431(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:hSb+gxuaM9SpCfjZegD+UwJVFTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQ80 uniprotkb:Q9Y6K9 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685149|imex:IM-28774-1833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349|entrezgene/locuslink:5036(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:7atBPwDeivTvSeEa/hQGWe6j0kE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:O14920 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-81266|uniprotkb:O75327|uniprotkb:B4E0U4|uniprotkb:B4DZ30|ensembl:ENSP00000430684 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:ikkb_human(display_long)|uniprotkb:IKBKB(gene name)|psi-mi:IKBKB(display_short)|uniprotkb:IKKB(gene name synonym)|uniprotkb:I-kappa-B kinase 2(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)|uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685141|imex:IM-28774-1831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_001177649.1|refseq:NP_001547.1|interpro:IPR000626(Ubiquitin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022007|interpro:IPR029071|interpro:IPR041185|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1990459"(transferrin receptor binding)|mint:O14920|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:4E3C|rcsb pdb:4KIK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209543|reactome:R-HSA-209560|ensembl:ENSG00000104365(gene)|ensembl:ENST00000520810(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|reactome:R-HSA-2871837|go:"GO:0019901"(protein kinase binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903140"(regulation of establishment of endothelial barrier)|refseq:NP_001229707.1|dip:DIP-27527N|entrezgene/locuslink:3551(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:Za/bWjmPFaKOGVvQ00rtBfikvhI9606 rigid:tV5LYXqK+3qJiubBkulfZGLpSG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:Q02535 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685133|imex:IM-28774-1829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rigid:Tzj4/cswX4qukMEdY+Wy68lhOZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P41134 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-1215527|uniprotkb:O00651|uniprotkb:O00652|uniprotkb:Q16371|uniprotkb:Q16377|uniprotkb:Q5TE66|uniprotkb:Q5TE67|uniprotkb:Q969Z7|uniprotkb:Q9H0Z5|uniprotkb:Q9H109|uniprotkb:A8K537|uniprotkb:E1P5L4|ensembl:ENSP00000365280 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:id1_human(display_long)|uniprotkb:ID1(gene name)|psi-mi:ID1(display_short)|uniprotkb:ID(gene name synonym)|uniprotkb:Inhibitor of DNA binding 1(gene name synonym)|uniprotkb:BHLHB24(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 24(gene name synonym)|uniprotkb:Inhibitor of differentiation 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685125|imex:IM-28774-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:NP_002156.2|refseq:NP_851998.1|dip:DIP-38112N|ensembl:ENSG00000125968(gene)|ensembl:ENST00000376112(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036164"(cell-abiotic substrate adhesion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070628"(proteasome binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901342"(regulation of vasculature development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:P41134|reactome:R-HSA-2559585|reactome:R-HSA-9031628|entrezgene/locuslink:3397(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:IVXAJsAnQLB8hVutO0qX4bS8gXM9606 rigid:cTPRpd0cApMHTBU1ntxTUyj8sBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P14317 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685117|imex:IM-28774-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606 rigid:lK0ADAZBzvEoSrKXMQO+9FD8nxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P29083 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685109|imex:IM-28774-1827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:tirhdOoblBsAZ90QQRdOgqsU3AQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y6K9 uniprotkb:P68104 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685101|imex:IM-28774-1379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|entrezgene/locuslink:1915(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:ttwkILHaNUGG4yjdJKDfOYtDFNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:O00267 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685093|imex:IM-28774-1825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N|entrezgene/locuslink:6829(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:tZJPKVqVZ2TqMfQMC81PF3nFy8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:P05423 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685085|imex:IM-28774-2265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N|entrezgene/locuslink:661(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:tlJn18uQtifpOy0gHiLaNAEkCEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:P37231 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685077|imex:IM-28774-2693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:Xl0pxj9VjX+dlhuiL94u7VjiNC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q96IT1 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685069|imex:IM-28774-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|entrezgene/locuslink:2908(identity) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rigid:n5qhyP2tL6pV9MnFsltpdD4dv9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:Q8IYH5 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685061|imex:IM-28774-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|entrezgene/locuslink:26009(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:kIYKv81th3pwdGqCBPoNmN/XzfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:Q9NQC1 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q6IE80|uniprotkb:Q96GQ6|ensembl:ENSP00000378451 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685053|imex:IM-28774-3553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|mint:Q9NQC1|reactome:R-HSA-3214847|entrezgene/locuslink:23338(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 rigid:d6KfPmh0nw5Rkiq6avGWaq4rEPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:Q7Z5J4 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685045|imex:IM-28774-1823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616|entrezgene/locuslink:10743(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 rigid:a091ZHJVqivQ+oMWwVSILhv+mhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96IT1 uniprotkb:Q99909 intact:EBI-743906|uniprotkb:Q8TBS2|ensembl:ENSP00000294753|ensembl:ENSP00000507236 intact:EBI-10295431|uniprotkb:O60223|uniprotkb:Q9BRW7|uniprotkb:Q5JQZ3|ensembl:ENSP00000298396 psi-mi:zn496_human(display_long)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 17(gene name synonym)|uniprotkb:ZNF496(gene name)|psi-mi:ZNF496(display_short)|uniprotkb:ZKSCAN17(gene name synonym) psi-mi:ssx3_human(display_long)|uniprotkb:SSX3(gene name)|psi-mi:SSX3(display_short)|uniprotkb:Cancer/testis antigen 5.3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685037|imex:IM-28774-915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116141.1|refseq:XP_005273385.1|ensembl:ENSG00000162714(gene)|ensembl:ENST00000294753(transcript)|ensembl:ENST00000682384(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027767|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|entrezgene/locuslink:84838(identity) refseq:NP_066294.1|refseq:XP_011542187.1|ensembl:ENSG00000165584(gene)|ensembl:ENST00000298396(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:10214(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:rc+LTwSYrhXPLq9te9gIOqj2XnY9606 rogid:jSB31TCCfnAP7jshF00a7bTb/sA9606 rigid:srD5a6TBRIxN4smAhTyRx8vJAL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHM5 uniprotkb:Q8N653 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685029|imex:IM-28774-2263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|entrezgene/locuslink:84678(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:5MaD6tF5qhrDhiybMFeHNtCdNBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHM5 uniprotkb:Q15744 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-3907048|uniprotkb:Q15745|uniprotkb:Q8IYI2|uniprotkb:Q99803|ensembl:ENSP00000206513 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:cebpe_human(display_long)|uniprotkb:CEBPE(gene name)|psi-mi:CEBPE(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685021|imex:IM-28774-2261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|entrezgene/locuslink:84678(identity) refseq:NP_001796.2|ensembl:ENSG00000092067(gene)|ensembl:ENST00000206513(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0006952"(defense response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:Q15744|rcsb pdb:3T92|reactome:R-HSA-9616222|entrezgene/locuslink:1053(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:utgZ/VFoYiiVekpXZDV+X8Xuj2s9606 rigid:DsQL+lbzUSCx3hZE5dm2EmA0QXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BXG8 uniprotkb:P17482 intact:EBI-8483734|intact:MINT-8417723|uniprotkb:Q8N7E9|uniprotkb:B2RA21|uniprotkb:Q8N4P1|ensembl:ENSP00000369611 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:spz1_human(display_long)|uniprotkb:SPZ1(gene name)|psi-mi:SPZ1(display_short)|uniprotkb:TSP1(gene name synonym)|uniprotkb:Testis-specific protein 1(gene name synonym)|uniprotkb:Testis-specific protein NYD-TSP1(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685013|imex:IM-28774-3101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115956.3|ensembl:ENSG00000164299(gene)|ensembl:ENST00000296739(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR042961|mint:Q9BXG8|entrezgene/locuslink:84654(identity) refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482|entrezgene/locuslink:3219(identity) - comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:h4CRsSUnYWDNdn2+ZMeO50NkKcc9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:5G8mO3izqfQ67ACN/Qsf9O+Rr/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UBX0 uniprotkb:Q99743 intact:EBI-8470369|intact:MINT-8417673|uniprotkb:Q99667|uniprotkb:Q52LC5|ensembl:ENSP00000295934|ensembl:ENSP00000498190 intact:EBI-3932727|uniprotkb:Q86V96|uniprotkb:Q4ZFV9|uniprotkb:Q99629|uniprotkb:Q53SQ3|ensembl:ENSP00000338283 psi-mi:hesx1_human(display_long)|uniprotkb:HESX1(gene name)|psi-mi:HESX1(display_short)|uniprotkb:HANF(gene name synonym)|uniprotkb:Homeobox protein ANF(gene name synonym) psi-mi:npas2_human(display_long)|uniprotkb:NPAS2(gene name)|psi-mi:NPAS2(display_short)|uniprotkb:BHLHE9(gene name synonym)|uniprotkb:MOP4(gene name synonym)|uniprotkb:PASD4(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP4(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 9(gene name synonym)|uniprotkb:Member of PAS protein 4(gene name synonym)|uniprotkb:PAS domain-containing protein 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685357|imex:IM-28774-3111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532506.1|refseq:XP_011532507.1|refseq:NP_003856.1|refseq:XP_005265583.1|refseq:XP_006713442.1|refseq:XP_016862910.1|ensembl:ENSG00000163666(gene)|ensembl:ENST00000295934(transcript)|ensembl:ENST00000647958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0010467"(gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR043402|mint:Q9UBX0|rcsb pdb:2K40|entrezgene/locuslink:8820(identity) ensembl:ENSG00000170485(gene)|ensembl:ENST00000335681(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007417"(central nervous system development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042493"|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-400253|reactome:R-HSA-9707616|refseq:NP_002509.2|dip:DIP-60821N|entrezgene/locuslink:4862(identity) - comment:mint|comment:homomint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ZnU6Y5Ypmp2rPpmN9ONoyIJgGhg9606 rogid:XeKPOy2H9eb+ZoZvP64cuSIxZUg9606 rigid:6XNTSIn4CVmPHy0k+X+AL8SLDGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15379 uniprotkb:Q01844 intact:EBI-607682|uniprotkb:O43268|uniprotkb:Q9UEI5|uniprotkb:Q9UEV0|uniprotkb:D3DQE1|ensembl:ENSP00000302967 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:hdac3_human(display_long)|uniprotkb:HDAC3(gene name)|psi-mi:HDAC3(display_short)|uniprotkb:RPD3-2(gene name synonym)|uniprotkb:SMAP45(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685365|imex:IM-28774-1387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003874.2|dip:DIP-24253N|ensembl:ENSG00000171720(gene)|ensembl:ENST00000305264(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O15379|rcsb pdb:4A69|reactome:R-HSA-1368071|reactome:R-HSA-193670|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-390471|reactome:R-HSA-400206|reactome:R-HSA-5617472|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-400253|entrezgene/locuslink:8841(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:X5pnE98s15eXKev3nauN7ri5kqg9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:Ff3W7DTeZlYp7pIZ4mxeYRzsWdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86U70 uniprotkb:P61371 intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277 intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658 psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym) psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685373|imex:IM-28774-3559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106878.1|refseq:NP_003884.1|dip:DIP-31826N|ensembl:ENSG00000198728(gene)|ensembl:ENST00000673968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|reactome:R-HSA-8939236|reactome:R-HSA-9010553|entrezgene/locuslink:8861(identity) refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606 rigid:6yTQlgK0DBgAPbZXwk6SvdyzMOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HR3 uniprotkb:O75177 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685509|imex:IM-28774-2709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|entrezgene/locuslink:90390(identity) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1|entrezgene/locuslink:26039(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:g0RWWY/4jHDHMv0CVAVnPHRY6G4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q969G2 uniprotkb:P61371 intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726 intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658 psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short) psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685501|imex:IM-28774-2285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553|entrezgene/locuslink:89884(identity) refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity) - crc64:6499F38E78B79FD1 - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606 rigid:f5SmlL+6DqqvbCyYC1owURRacxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:O43513 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685493|imex:IM-28774-1393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:WczJxoyp+87ULQzEjIrsU7QMTPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:Q9C019 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685477|imex:IM-28774-2283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rigid:HMBZIJ4PWe7CHtNjmmX4a5wxOGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:Q9H9B1 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685469|imex:IM-28774-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|entrezgene/locuslink:79813(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 rigid:XrFJwdJGK2fubK4gogMYFDQ0sW0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:Q9HBM6 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-751601|uniprotkb:Q9Y2S3|uniprotkb:B2RUZ9|ensembl:ENSP00000339917 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:taf9b_human(display_long)|uniprotkb:Transcription initiation factor TFIID subunit 9-like(gene name synonym)|uniprotkb:Transcription-associated factor TAFII31L(gene name synonym)|uniprotkb:Neuronal cell death-related protein 7(gene name synonym)|uniprotkb:TAF9B(gene name)|psi-mi:TAF9B(display_short)|uniprotkb:TAF9L(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685461|imex:IM-28774-2281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:NP_057059.2|ensembl:ENSG00000187325(gene)|ensembl:ENST00000341864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q9HBM6|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:51616(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:8+i5lmcx4OcgCEbk2F9MS8bYhos9606 rigid:/xvuyoBdNtbIxOJVxrhnvMJHl+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:P10244 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-1389468|uniprotkb:B2RBS5|uniprotkb:B7Z8D9|uniprotkb:F8W6N6|uniprotkb:Q53F07|ensembl:ENSP00000217026 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:mybb_human(display_long)|uniprotkb:Myb-like protein 2(gene name synonym)|uniprotkb:MYBL2(gene name)|psi-mi:MYBL2(display_short)|uniprotkb:BMYB(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685453|imex:IM-28774-1847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:NP_001265539.1|refseq:NP_002457.1|ensembl:ENSG00000101057(gene)|ensembl:ENST00000217026(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|mint:P10244|rcsb pdb:6C48|reactome:R-HSA-1362300|reactome:R-HSA-156711|reactome:R-HSA-8869496|entrezgene/locuslink:4605(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:2ldntN2B+u1fHcK4WPkL9UZYbzs9606 rigid:Iwo3/orYIANAx9M2sdBdkUgYW+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:Q13568 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685445|imex:IM-28774-2707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1|entrezgene/locuslink:3663(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606 rigid:x3cGEniLgsu9Xz7j4pjoPvjjkM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:P29083 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685437|imex:IM-28774-2705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:WTvArSgJipXRSCHWck6nuvcLYSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C019 uniprotkb:Q13573 intact:EBI-2342111|uniprotkb:Q9C018|uniprotkb:O95604|uniprotkb:Q8IUX9|uniprotkb:A2BEC9|ensembl:ENSP00000259930|ensembl:ENSP00000365884|ensembl:ENSP00000403221|ensembl:ENSP00000411683|ensembl:ENSP00000413961|ensembl:ENSP00000415480 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:tri15_human(display_long)|uniprotkb:TRIM15(gene name)|psi-mi:TRIM15(display_short)|uniprotkb:RNF93(gene name synonym)|uniprotkb:ZNF178(gene name synonym)|uniprotkb:ZNFB7(gene name synonym)|uniprotkb:Zinc finger protein B7(gene name synonym)|uniprotkb:RING finger protein 93(gene name synonym)|uniprotkb:Zinc finger protein 178(gene name synonym) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685429|imex:IM-28774-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_150232.2|ensembl:ENSG00000137384(gene)|ensembl:ENSG00000204610(gene)|ensembl:ENSG00000227147(gene)|ensembl:ENSG00000233599(gene)|ensembl:ENSG00000235259(gene)|ensembl:ENSG00000235960(gene)|ensembl:ENST00000259930(transcript)|ensembl:ENST00000376694(transcript)|ensembl:ENST00000414873(transcript)|ensembl:ENST00000421984(transcript)|ensembl:ENST00000427091(transcript)|ensembl:ENST00000431059(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR018957|interpro:IPR043136|entrezgene/locuslink:89870(identity) refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N|entrezgene/locuslink:22938(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:W8K5SsgQmtSbl6MPUPA4bF4nd6k9606 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 rigid:zuAyDZE2Aml/sU8Aq9ena/Jqfxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q92522 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685421|imex:IM-28774-1391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63|entrezgene/locuslink:8971(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 rigid:p68C4wjUNewpZURgZ3Jsh6PKLV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q96I24 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685413|imex:IM-28774-3113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N|entrezgene/locuslink:8939(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:QwpeFdcFuh0uA7+RZxHcRiAvhDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96I24 uniprotkb:Q16384 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 intact:EBI-10237585|uniprotkb:A3KN76|uniprotkb:Q5JQ64|uniprotkb:Q08AJ2|ensembl:ENSP00000366118 psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:ssx1_human(display_long)|uniprotkb:SSX1(gene name)|psi-mi:SSX1(display_short)|uniprotkb:Cancer/testis antigen 5.1(gene name synonym)|uniprotkb:Synovial sarcoma, X breakpoint 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685405|imex:IM-28774-919 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N|entrezgene/locuslink:8939(identity) refseq:NP_001265620.1|refseq:NP_005626.1|ensembl:ENSG00000126752(gene)|ensembl:ENST00000376919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR028804|interpro:IPR036051|entrezgene/locuslink:6756(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rogid:Sr2H4AP0aOUyEOnG6tdL1ZY2dPI9606 rigid:/X4xYHFZj6JZUsGQ4QESHlTKZno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96I24 uniprotkb:P55771 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685397|imex:IM-28774-2699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N|entrezgene/locuslink:8939(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:lO5JXtVEnz+rgxK4v0D5n64K8bA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UNS1 uniprotkb:P61457 intact:EBI-2212315|intact:EBI-2561400|uniprotkb:B2ZAV0|uniprotkb:O94802|uniprotkb:Q86VM1|uniprotkb:Q8IWH3|ensembl:ENSP00000450607 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:tim_human(display_long)|uniprotkb:TIMELESS(gene name)|psi-mi:TIMELESS(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:TIM1(gene name synonym)|uniprotkb:TIMELESS1(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685389|imex:IM-28774-2279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003911.2|refseq:NP_001317224.1|dip:DIP-47395N|ensembl:ENSG00000111602(gene)|ensembl:ENST00000553532(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009582"(detection of abiotic stimulus)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043111"(replication fork arrest)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:1904976"(cellular response to bleomycin)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR006906(Timeless protein)|interpro:IPR007725(Timeless C-terminal)|rcsb pdb:4XHT|rcsb pdb:4XHU|rcsb pdb:4XHW|rcsb pdb:5MQI|rcsb pdb:6T9Q|rcsb pdb:6TAZ|reactome:R-HSA-5693607|entrezgene/locuslink:8914(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:lFzdtUFz91sT6BcYbkFDEmPU3KU9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:4oihD5vQga68nJqpfdcKk6LvNmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86U70 uniprotkb:O60663 intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277 intact:EBI-296386|uniprotkb:O75463|uniprotkb:Q5JU95|uniprotkb:Q6ISC9|ensembl:ENSP00000362573|uniprotkb:F8W7W6 psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym) psi-mi:lmx1b_human(display_long)|uniprotkb:LMX1B(gene name)|psi-mi:LMX1B(display_short)|uniprotkb:LIM/homeobox protein LMX1B(gene name synonym)|uniprotkb:LIM/homeobox protein 1.2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685381|imex:IM-28774-1389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106878.1|refseq:NP_003884.1|dip:DIP-31826N|ensembl:ENSG00000198728(gene)|ensembl:ENST00000673968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|reactome:R-HSA-8939236|reactome:R-HSA-9010553|entrezgene/locuslink:8861(identity) go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000136944(gene)|ensembl:ENST00000373474(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|go:"GO:0001701"(in utero embryonic development)|refseq:NP_001167618.1|refseq:NP_002307.2|entrezgene/locuslink:4010(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606 rogid:ERk5ljL48TxeUJQiYNxmIRYKNI89606 rigid:6PVvpF82PlmhNmMpOvIxUBpIgi8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TBZ5 uniprotkb:O43763 intact:EBI-10273699|ensembl:ENSP00000296091|ensembl:ENSP00000397390|ensembl:ENSP00000406469|ensembl:ENSP00000485847|ensembl:ENSP00000486576|ensembl:ENSP00000487139 intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48 psi-mi:zn502_human(display_long)|uniprotkb:ZNF502(gene name)|psi-mi:ZNF502(display_short) psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685621|imex:IM-28774-3561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127912.1|refseq:NP_001127913.1|refseq:NP_001127914.1|refseq:NP_001269809.1|refseq:NP_149987.2|ensembl:ENSG00000196653(gene)|ensembl:ENSG00000281448(gene)|ensembl:ENST00000296091(transcript)|ensembl:ENST00000436624(transcript)|ensembl:ENST00000449836(transcript)|ensembl:ENST00000626630(transcript)|ensembl:ENST00000628995(transcript)|ensembl:ENST00000630464(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_016862929.1|entrezgene/locuslink:91392(identity) ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1|entrezgene/locuslink:3196(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:B6gDYEuaVp0HNm61iXXEVTi47Xc9606 rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606 rigid:JdN/I8Cw+N0FFEbEH6Ztn4O2eBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43439 uniprotkb:Q16559 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-10237959|uniprotkb:A0AVI7|ensembl:ENSP00000334547 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:tal2_human(display_long)|uniprotkb:TAL2(gene name)|psi-mi:TAL2(display_short)|uniprotkb:BHLHA19(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685613|imex:IM-28774-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) refseq:NP_005412.1|ensembl:ENSG00000186051(gene)|ensembl:ENST00000334077(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021794"(thalamus development)|go:"GO:0030901"(midbrain development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040238|entrezgene/locuslink:6887(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:JgO8ZFHP9X70qLk3jzH1SbU+xiU9606 rigid:+gXE+2Obm5EULntG47EQwLVr4Mo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43439 uniprotkb:Q92886 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-10279647|uniprotkb:Q96HE1|uniprotkb:Q5U0Q9|ensembl:ENSP00000317580 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:ngn1_human(display_long)|uniprotkb:NEUROG1(gene name)|psi-mi:NEUROG1(display_short)|uniprotkb:BHLHA6(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 6(gene name synonym)|uniprotkb:NEUROD3(gene name synonym)|uniprotkb:NGN(gene name synonym)|uniprotkb:NGN1(gene name synonym)|uniprotkb:Neurogenic basic-helix-loop-helix protein(gene name synonym)|uniprotkb:Neurogenic differentiation factor 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685605|imex:IM-28774-1395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) refseq:NP_006152.2|ensembl:ENSG00000181965(gene)|ensembl:ENST00000314744(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0007399"(nervous system development)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032653|interpro:IPR036638|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|entrezgene/locuslink:4762(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:kz1JEusy5ubX6GwV80OmH4UQFEQ9606 rigid:zMSxH6t8myI3xrnex5Vx0zz3ews false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43439 uniprotkb:Q02535 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685597|imex:IM-28774-925 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628|entrezgene/locuslink:3399(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rigid:Po0KF4ZzyIQnQ0PKBDM6aUMMWyQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43439 uniprotkb:P29083 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-5462215|uniprotkb:Q16103|ensembl:ENSP00000283875 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:t2ea_human(display_long)|uniprotkb:GTF2E1(gene name)|psi-mi:GTF2E1(display_short)|uniprotkb:TF2E1(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685589|imex:IM-28774-2287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N|entrezgene/locuslink:9139(identity) refseq:XP_011511046.1|refseq:XP_011511047.1|refseq:NP_005504.2|dip:DIP-717N|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:P29083|rcsb pdb:1VD4|rcsb pdb:2JTX|rcsb pdb:2RNQ|rcsb pdb:2RNR|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|reactome:R-HSA-6807505|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|ensembl:ENSG00000153767(gene)|ensembl:ENST00000283875(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|entrezgene/locuslink:2960(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:rk6cZKAzOOFGD4hwuTjVAB1gvEg9606 rigid:enWaD0MtckmxZwK8Fv5VWgffJoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13287 uniprotkb:P42226 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685581|imex:IM-28774-1857 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1|entrezgene/locuslink:9111(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:Am7FDUDZ4pa6DXyqZ3JMJRIO2fU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13287 uniprotkb:P31274 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 intact:EBI-1779423|uniprotkb:Q9H1I0|uniprotkb:B2RCN7|ensembl:ENSP00000302836|ensembl:ENSP00000423861 psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:hxc9_human(display_long)|uniprotkb:HOXC9(gene name)|psi-mi:HOXC9(display_short)|uniprotkb:HOX3B(gene name synonym)|uniprotkb:Homeobox protein Hox-3B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685573|imex:IM-28774-3117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1|entrezgene/locuslink:9111(identity) refseq:NP_008828.1|ensembl:ENSG00000180806(gene)|ensembl:ENST00000303450(transcript)|ensembl:ENST00000508190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016235"(aggresome)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:2LP0|rcsb pdb:2MSY|entrezgene/locuslink:3225(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 rogid:lzgtm1kSHg9rIAgONAjCEdZfrXE9606 rigid:qBrVgobt77fFnh+W9QpVIlvRQH8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43679 uniprotkb:P61968 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|uniprotkb:D3DT23|ensembl:ENSP00000359573|ensembl:ENSP00000359575 psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685565|imex:IM-28774-1855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|entrezgene/locuslink:9079(identity) refseq:NP_006760.1|refseq:XP_005271348.1|ensembl:ENSG00000143013(gene)|ensembl:ENST00000370542(transcript)|ensembl:ENST00000370544(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P61968|go:"GO:0050865"(regulation of cell activation)|rcsb pdb:2L4Z|dip:DIP-41414N|entrezgene/locuslink:8543(identity) - crc64:E86387BA027F383A crc64:C8AC295144AD7787 figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606 rigid:pqhqoZe+3OzbDWAjQ/vzZOcb8mI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43679 uniprotkb:P61371 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658 psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685557|imex:IM-28774-1853 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|entrezgene/locuslink:9079(identity) refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity) - crc64:E86387BA027F383A - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606 rigid:UXaIAjz9xKttbAbZzWXMUrLPCqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43679 uniprotkb:P61371 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658 psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685549|imex:IM-28774-1851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363|entrezgene/locuslink:9079(identity) refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity) - crc64:E86387BA027F383A - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606 rigid:UXaIAjz9xKttbAbZzWXMUrLPCqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUE0 uniprotkb:Q9H0N5 intact:EBI-8063723|intact:MINT-7899478|uniprotkb:A2VCU1|ensembl:ENSP00000318502|ensembl:ENSP00000453750 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 psi-mi:tf2ly_human(display_long)|uniprotkb:TGIF2LY(gene name)|psi-mi:TGIF2LY(display_short)|uniprotkb:TGIF-like on the Y(gene name synonym)|uniprotkb:TGF-beta-induced transcription factor 2-like protein(gene name synonym)|uniprotkb:TGFB-induced factor 2-like protein, Y-linked(gene name synonym)|uniprotkb:TGIFLY(gene name synonym) psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685541|imex:IM-28774-923 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_631960.1|ensembl:ENSG00000176679(gene)|ensembl:ENST00000321217(transcript)|ensembl:ENST00000559055(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|mint:Q8IUE0|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|entrezgene/locuslink:90655(identity) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) - comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:VecFL7eXpB0tEjIXE7oNDLXyjJY9606 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rigid:4lIkkf2q4c3iz9fJNXxx9XzmCvk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00170 uniprotkb:Q9Y6K9 intact:EBI-704197|uniprotkb:Q2M3Q2|uniprotkb:Q99606|uniprotkb:A0SZW3|uniprotkb:A0SZW4|uniprotkb:A0SZW5|uniprotkb:A0SZW6|ensembl:ENSP00000279146 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:aip_human(display_long)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym)|uniprotkb:Immunophilin homolog ARA9(gene name synonym)|uniprotkb:HBV X-associated protein 2(gene name synonym)|uniprotkb:AIP(gene name)|psi-mi:AIP(display_short)|uniprotkb:XAP2(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685533|imex:IM-28774-1849 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003968.3|refseq:NP_001289888.1|refseq:NP_001289889.1|dip:DIP-34068N|ensembl:ENSG00000110711(gene)|ensembl:ENST00000279146(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036004"(GAF domain binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031208|interpro:IPR039663|mint:O00170|rcsb pdb:2LKN|rcsb pdb:4AIF|rcsb pdb:4APO|reactome:R-HSA-8937144|reactome:R-HSA-8950505|entrezgene/locuslink:9049(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:uCcvOG+bNnmT2zzm58nXhAzKbWo9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:VX6T041dCWg1KFK6UX89MAWbZgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HR3 uniprotkb:O94776 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685525|imex:IM-28774-921 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|entrezgene/locuslink:90390(identity) refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|entrezgene/locuslink:9219(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 rigid:Q+52qQEC8cJN5R/QAuCulyN4HCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HR3 uniprotkb:Q9H0N5 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-634289|uniprotkb:Q8TD40|ensembl:ENSP00000254908|ensembl:ENSP00000421544 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:phs2_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase 2(gene name synonym)|uniprotkb:DcoH-like protein DCoHm(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1 from muscle(gene name synonym)|uniprotkb:HNF-1-alpha dimerization cofactor(gene name synonym)|uniprotkb:PCBD2(gene name)|psi-mi:PCBD2(display_short)|uniprotkb:DCOH2(gene name synonym)|uniprotkb:DCOHM(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685517|imex:IM-28774-2711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|entrezgene/locuslink:90390(identity) refseq:NP_115527.3|ensembl:ENSG00000132570(gene)|ensembl:ENST00000254908(transcript)|ensembl:ENST00000512783(transcript)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|rcsb pdb:4C45|entrezgene/locuslink:84105(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:pFuv42zNbVBtFSZ8duBoohlDJGY9606 rigid:8T7tjYbD9rowAKUxNH3MPulRmno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75618 uniprotkb:P09016 intact:EBI-1043164|uniprotkb:O60737|ensembl:ENSP00000356985|ensembl:ENSP00000414821|ensembl:ENSP00000445835|ensembl:ENSP00000476946|uniprotkb:D3DVF5 intact:EBI-12822515|ensembl:ENSP00000302548|uniprotkb:B2R9R3|uniprotkb:Q96AU0 psi-mi:dedd_human(display_long)|uniprotkb:DEDPro1(gene name synonym)|uniprotkb:Death effector domain-containing testicular molecule(gene name synonym)|uniprotkb:FLDED-1(gene name synonym)|uniprotkb:DEDD(gene name)|psi-mi:DEDD(display_short)|uniprotkb:DEDPRO1(gene name synonym)|uniprotkb:DEFT(gene name synonym)|uniprotkb:KE05(orf name) psi-mi:hxd4_human(display_long)|uniprotkb:HOXD4(gene name)|psi-mi:HOXD4(display_short)|uniprotkb:HOX4B(gene name synonym)|uniprotkb:Homeobox protein HHO.C13(gene name synonym)|uniprotkb:Homeobox protein Hox-4B(gene name synonym)|uniprotkb:Homeobox protein Hox-5.1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685637|imex:IM-28774-2289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046697"(decidualization)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR038856|mint:O75618|ensembl:ENSG00000158796(gene)|ensembl:ENST00000368006(transcript)|ensembl:ENST00000458050(transcript)|ensembl:ENST00000490843(transcript)|ensembl:ENST00000545495(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001034800.1|refseq:NP_001034801.1|refseq:NP_127491.1|refseq:XP_016858291.1|dip:DIP-41944N|entrezgene/locuslink:9191(identity) ensembl:ENSG00000170166(gene)|ensembl:ENST00000306324(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030054"(cell junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|reactome:R-HSA-5617472|refseq:NP_055436.2|entrezgene/locuslink:3233(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:wcUMlOrbLzoDvmFg6ZjigXLSB1Y9606 rogid:VbQRgZOke/MUwpPupAQ0R3veQWY9606 rigid:WOiKTRIsn/85dqGNCciVXCdEE+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WUH1 uniprotkb:Q9UHV2 intact:EBI-11156883|ensembl:ENSP00000448050|ensembl:ENSP00000450165|ensembl:ENSP00000475473|uniprotkb:G3V214|uniprotkb:G3V1X3|uniprotkb:Q9H3K7|uniprotkb:B3KQ81 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 psi-mi:chur_human(display_long)|uniprotkb:CHURC1(gene name)|psi-mi:CHURC1(display_short)|uniprotkb:C14orf52(gene name synonym)|uniprotkb:CHCH(gene name synonym)|uniprotkb:My015(orf name) psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685629|imex:IM-28774-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190992.1|refseq:NP_001190993.1|refseq:NP_660148.3|ensembl:ENSG00000258289(gene)|ensembl:ENST00000548752(transcript)|ensembl:ENST00000549115(transcript)|ensembl:ENST00000607599(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009508(Churchill)|interpro:IPR038543|mint:Q8WUH1|rcsb pdb:2JOX|entrezgene/locuslink:91612(identity) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:WKqPPbQGe0cMce6ZEUDae229/jU9606 rogid:40dvjniwxY/UQiyoVREicctpWe09606 rigid:/MTGxpbW0WytGouIjf0elfgTuSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TC84 uniprotkb:Q8N653 intact:EBI-21975404|uniprotkb:Q6UXY9|uniprotkb:Q6X7T6|ensembl:ENSP00000357682 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:fank1_human(display_long)|uniprotkb:FANK1(gene name)|psi-mi:FANK1(display_short)|uniprotkb:HSD13(orf name)|uniprotkb:UNQ6504/PRO21382(orf name) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685653|imex:IM-28774-3119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_660278.3|refseq:XP_011538652.1|ensembl:ENSG00000203780(gene)|ensembl:ENST00000368693(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0097546"(ciliary base)|interpro:IPR002110(Ankyrin)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020683|interpro:IPR036116|interpro:IPR036770|entrezgene/locuslink:92565(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pRpoTkcIFF7QAo2XBmAYZHeJi3Q9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:Mv55epbnBxOr+m1qcqNNnceCxFA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15209 uniprotkb:P15976 intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007 intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858 psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym) psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685661|imex:IM-28774-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N|entrezgene/locuslink:9278(identity) refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N|entrezgene/locuslink:2623(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606 rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606 rigid:zEdZ/RQW8ry6oUe3iSSFogApJsM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15650 uniprotkb:P55771 intact:EBI-2800143|uniprotkb:Q96ED7|uniprotkb:Q9UKH0|uniprotkb:B2RAS0|ensembl:ENSP00000261884 intact:EBI-12111000|ensembl:ENSP00000355245|ensembl:ENSP00000384817|uniprotkb:Q99582|uniprotkb:Q9UQR4 psi-mi:trip4_human(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:TRIP4(gene name)|psi-mi:TRIP4(display_short)|uniprotkb:RQT4(gene name synonym) psi-mi:pax9_human(display_long)|uniprotkb:PAX9(gene name)|psi-mi:PAX9(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685669|imex:IM-28774-3121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057297.2|refseq:NP_001308853.1|ensembl:ENSG00000103671(gene)|ensembl:ENST00000261884(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|rcsb pdb:2E5O|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:9325(identity) ensembl:ENSG00000198807(gene)|ensembl:ENST00000361487(transcript)|ensembl:ENST00000402703(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0042476"(odontogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033204|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|go:"GO:0042481"(regulation of odontogenesis)|refseq:NP_006185.1|entrezgene/locuslink:5083(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fecS9E0obnl+xsx/r9OrmToZEbs9606 rogid:YCvZIY7nOXCJJnZCn9UYVzppeBw9606 rigid:Ps0LC+1fnQDgAR66uHBZlvpN5Tk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15650 uniprotkb:P24468 intact:EBI-2800143|uniprotkb:Q96ED7|uniprotkb:Q9UKH0|uniprotkb:B2RAS0|ensembl:ENSP00000261884 intact:EBI-2795198|uniprotkb:B6ZGU1|uniprotkb:Q03754|uniprotkb:B4DQJ2|uniprotkb:Q3KQR7|ensembl:ENSP00000377721 psi-mi:trip4_human(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:TRIP4(gene name)|psi-mi:TRIP4(display_short)|uniprotkb:RQT4(gene name synonym) psi-mi:cot2_human(display_long)|uniprotkb:NR2F2(gene name)|psi-mi:NR2F2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:TFCOUP2(gene name synonym)|uniprotkb:COUP transcription factor II(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group F member 2(gene name synonym)|uniprotkb:Apolipoprotein A-I regulatory protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685677|imex:IM-28774-3565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057297.2|refseq:NP_001308853.1|ensembl:ENSG00000103671(gene)|ensembl:ENST00000261884(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|rcsb pdb:2E5O|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:9325(identity) refseq:NP_066285.1|refseq:NP_001138627.1|refseq:NP_001138628.1|refseq:NP_001138629.1|ensembl:ENSG00000185551(gene)|ensembl:ENST00000394166(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0009956"(radial pattern formation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032355"(response to estradiol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060173"(limb development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3CJW|reactome:R-HSA-381340|dip:DIP-29713N|entrezgene/locuslink:7026(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:fecS9E0obnl+xsx/r9OrmToZEbs9606 rogid:XsZyqUr06sQQaD3oXAA3IEa6Dug9606 rigid:JrwbWBdRgKdnWO4AfoDl5luONls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17861 uniprotkb:Q15650 intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6 intact:EBI-2800143|uniprotkb:Q96ED7|uniprotkb:Q9UKH0|uniprotkb:B2RAS0|ensembl:ENSP00000261884 psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym) psi-mi:trip4_human(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:TRIP4(gene name)|psi-mi:TRIP4(display_short)|uniprotkb:RQT4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685685|imex:IM-28774-3123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|entrezgene/locuslink:7494(identity) refseq:NP_057297.2|refseq:NP_001308853.1|ensembl:ENSG00000103671(gene)|ensembl:ENST00000261884(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|rcsb pdb:2E5O|go:"GO:0005815"(microtubule organizing center)|entrezgene/locuslink:9325(identity) - function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606 rogid:fecS9E0obnl+xsx/r9OrmToZEbs9606 rigid:ROaHTOqxMfpPInLllL8CLMiZG8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15649 uniprotkb:O14770 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685693|imex:IM-28774-1859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1|entrezgene/locuslink:9326(identity) ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N|entrezgene/locuslink:4212(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 rigid:ZqpjqOcVvV8/Ly5f0JMgErLBJcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15649 uniprotkb:P40426 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 intact:EBI-6390275|ensembl:ENSP00000362588|uniprotkb:E9PB27|uniprotkb:Q5JSA0|uniprotkb:Q5JSA1|uniprotkb:Q5VXL3|uniprotkb:Q96PF9|uniprotkb:Q96PG0 psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:pbx3_human(display_long)|uniprotkb:PBX3(gene name)|psi-mi:PBX3(display_short)|uniprotkb:Homeobox protein PBX3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685701|imex:IM-28774-1397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1|entrezgene/locuslink:9326(identity) go:"GO:0007388"(posterior compartment specification)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000167081(gene)|ensembl:ENST00000373489(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007387"(anterior compartment pattern formation)|refseq:NP_001317711.1|refseq:NP_001128250.1|refseq:NP_006186.1|entrezgene/locuslink:5090(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rogid:rNcJlzEcD3iy96im+EIHO+mOfqU9606 rigid:w6kNqY4tukwR8CNnqWgABcxgXyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15649 uniprotkb:Q99697 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 intact:EBI-1175211|uniprotkb:O60578|uniprotkb:O60579|uniprotkb:O60580|uniprotkb:Q9BY17|ensembl:ENSP00000347004|ensembl:ENSP00000378095|ensembl:ENSP00000481951|ensembl:ENSP00000484763|uniprotkb:B2RA02|uniprotkb:B3KXS0|uniprotkb:Q3KQX9|uniprotkb:A8K6C6 psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:pitx2_human(display_long)|uniprotkb:RIEG bicoid-related homeobox transcription factor(gene name synonym)|uniprotkb:Solurshin(gene name synonym)|uniprotkb:ALL1-responsive protein ARP1(gene name synonym)|uniprotkb:PITX2(gene name)|psi-mi:PITX2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:RGS(gene name synonym)|uniprotkb:RIEG(gene name synonym)|uniprotkb:RIEG1(gene name synonym)|uniprotkb:Paired-like homeodomain transcription factor 2(gene name synonym)|uniprotkb:Homeobox protein PITX2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685709|imex:IM-28774-1867 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1|entrezgene/locuslink:9326(identity) ensembl:ENSG00000164093(gene)|ensembl:ENST00000354925(transcript)|ensembl:ENST00000394595(transcript)|ensembl:ENST00000613094(transcript)|ensembl:ENST00000614423(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_000316.2|refseq:NP_001191326.1|refseq:NP_001191327.1|refseq:NP_001191328.1|refseq:NP_700475.1|refseq:NP_700476.1|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035993"(deltoid tuberosity development)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060127"(prolactin secreting cell differentiation)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061325"(cell proliferation involved in outflow tract morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070986"(left/right axis specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003654(Paired-like homeodomain protein, OAR)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016233(Homeobox Pitx/unc30)|interpro:IPR017970|mint:Q99697|rcsb pdb:2L7F|rcsb pdb:2L7M|rcsb pdb:2LKX|reactome:R-HSA-8866906|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|refseq:XP_011530329.1|entrezgene/locuslink:5308(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rogid:JWKFsTNDJOefVhq9VKgHa4A1C8g9606 rigid:tccHBTtDrHRGQnLh/7zRuQopMU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15649 uniprotkb:O43542 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 intact:EBI-2849976|uniprotkb:Q9BU18|uniprotkb:O43568|ensembl:ENSP00000343392|ensembl:ENSP00000451362|ensembl:ENSP00000451974|ensembl:ENSP00000452598 psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:xrcc3_human(display_long)|uniprotkb:XRCC3(gene name)|psi-mi:XRCC3(display_short)|uniprotkb:X-ray repair cross-complementing protein 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685717|imex:IM-28774-3125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1|entrezgene/locuslink:9326(identity) refseq:XP_011535440.1|refseq:NP_001093588.1|refseq:NP_001093589.1|refseq:NP_005423.1|refseq:XP_005268103.1|dip:DIP-42016N|ensembl:ENSG00000126215(gene)|ensembl:ENST00000352127(transcript)|ensembl:ENST00000553264(transcript)|ensembl:ENST00000554913(transcript)|ensembl:ENST00000555055(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010033"(response to organic substance)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0033065"(Rad51C-XRCC3 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071140"(resolution of mitotic recombination intermediates)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090656"(t-circle formation)|go:"GO:0090657"(telomeric loop disassembly)|go:"GO:0090737"(telomere maintenance via telomere trimming)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0005524"(ATP binding)|entrezgene/locuslink:7517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rogid:3vDLDeKRnmV6Wg9dK2yMbIRqzVk9606 rigid:ARxqneqVS/x29kixj+JIatAMfsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15649 uniprotkb:P17028 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685725|imex:IM-28774-3567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1|entrezgene/locuslink:9326(identity) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR|entrezgene/locuslink:7572(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rigid:Vq8/bz9PVHawtuuPGyAbj2kyrdM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15649 uniprotkb:O60667 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 intact:EBI-2809270|ensembl:ENSP00000356058|uniprotkb:A8K7J2|uniprotkb:B7Z6Z0|uniprotkb:D9MWM3 psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:faim3_human(display_long)|uniprotkb:FCMR(gene name)|psi-mi:FCMR(display_short)|uniprotkb:FAIM3(gene name synonym)|uniprotkb:IgM Fc fragment receptor(gene name synonym)|uniprotkb:Regulator of Fas-induced apoptosis Toso(gene name synonym)|uniprotkb:TOSO(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685733|imex:IM-28774-2291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1|entrezgene/locuslink:9326(identity) ensembl:ENSG00000162894(gene)|ensembl:ENST00000367091(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_001135945.1|refseq:NP_001180267.1|refseq:NP_005440.1|entrezgene/locuslink:9214(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rogid:Yt3zQ0fOJl3PACiIx5FPWFC6eQI9606 rigid:zZmG9Dstt0edJfznaIDnN3pt3vs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q8 uniprotkb:P15884 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 intact:EBI-533224|uniprotkb:Q08AP3|uniprotkb:Q08AP2|uniprotkb:Q15440|uniprotkb:Q15441|uniprotkb:Q15439|uniprotkb:B4DT37|ensembl:ENSP00000348374|ensembl:ENSP00000457649|uniprotkb:G0LNT9|uniprotkb:G0LNU0|uniprotkb:G0LNU1|uniprotkb:G0LNU2|uniprotkb:G0LNU8|uniprotkb:G0LNU9|uniprotkb:G0LNV0|uniprotkb:G0LNV1|uniprotkb:B3KT62|uniprotkb:B3KUC0|uniprotkb:B4DUG3|uniprotkb:B7Z5M6|uniprotkb:G0LNU5|uniprotkb:H3BPQ1|uniprotkb:B7Z6Y1|uniprotkb:G0LNU4|uniprotkb:G0LNV2 psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:itf2_human(display_long)|uniprotkb:Immunoglobulin transcription factor 2(gene name synonym)|uniprotkb:SL3-3 enhancer factor 2(gene name synonym)|uniprotkb:ITF2(gene name synonym)|uniprotkb:SEF2(gene name synonym)|uniprotkb:TCF4(gene name)|psi-mi:TCF4(display_short)|uniprotkb:BHLHB19(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685741|imex:IM-28774-3569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N|entrezgene/locuslink:9328(identity) refseq:NP_001230155.2|refseq:NP_001077431.1|refseq:NP_001230163.1|refseq:NP_003190.1|refseq:XP_005266796.2|ensembl:ENSG00000196628(gene)|ensembl:ENST00000356073(transcript)|ensembl:ENST00000564999(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070888"(E-box binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P15884|rcsb pdb:2KWF|rcsb pdb:6OD3|rcsb pdb:6OD4|rcsb pdb:6OD5|reactome:R-HSA-525793|refseq:NP_001335140.1|refseq:NP_001335141.1|refseq:NP_001335142.1|refseq:NP_001335143.1|refseq:NP_001335144.1|refseq:NP_001335145.1|refseq:NP_001335146.1|refseq:NP_001335147.1|refseq:NP_001335148.1|refseq:NP_001335149.1|refseq:NP_001293136.1|refseq:NP_001293137.1|refseq:NP_001230164.1|refseq:NP_001230165.1|refseq:NP_001230160.1|refseq:NP_001230161.1|refseq:NP_001230162.1|refseq:XP_006722599.1|refseq:XP_006722600.1|refseq:NP_001230156.1|refseq:NP_001230157.1|refseq:NP_001230159.1|refseq:XP_016881425.1|refseq:XP_016881429.1|refseq:XP_016881430.1|refseq:XP_016881435.1|refseq:XP_016881445.1|dip:DIP-163N|entrezgene/locuslink:6925(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 rogid:5ofdcOZrL/NXfVfFMVO8GMyh+ZY9606 rigid:MwvqRDHKylnin6zIBDdNmN9+PTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q8 uniprotkb:O43680 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 intact:EBI-723267|uniprotkb:O43545|uniprotkb:Q9BZ14|ensembl:ENSP00000237316|ensembl:ENSP00000356857|uniprotkb:Q6ICV0|uniprotkb:E1P581 psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:tcf21_human(display_long)|uniprotkb:Podocyte-expressed 1(gene name synonym)|uniprotkb:Epicardin(gene name synonym)|uniprotkb:Capsulin(gene name synonym)|uniprotkb:TCF21(gene name)|psi-mi:TCF21(display_short)|uniprotkb:POD1(gene name synonym)|uniprotkb:BHLHA23(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685749|imex:IM-28774-1869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N|entrezgene/locuslink:9328(identity) refseq:NP_003197.2|refseq:NP_938206.1|ensembl:ENSG00000118526(gene)|ensembl:ENST00000237316(transcript)|ensembl:ENST00000367882(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007530"(sex determination)|go:"GO:0014707"(branchiomeric skeletal muscle development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032502"(developmental process)|go:"GO:0032835"(glomerulus development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048536"(spleen development)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060426"(lung vasculature development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060539"(diaphragm development)|go:"GO:0060541"(respiratory system development)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070888"(E-box binding)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072277"(metanephric glomerular capillary formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|entrezgene/locuslink:6943(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 rogid:HM3PKV+KjNvRwhNPBsE5jsuyqd09606 rigid:65fsy62SSECD65DXyEWxzaX+l0E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q9 uniprotkb:P61457 intact:EBI-1054873|uniprotkb:Q4ZG48|uniprotkb:Q86XJ8|uniprotkb:Q8WX84|uniprotkb:Q96B44|uniprotkb:Q9H5I8|uniprotkb:Q9NT97|intact:EBI-1237212|ensembl:ENSP00000263956 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:tf3c3_human(display_long)|uniprotkb:GTF3C3(gene name)|psi-mi:GTF3C3(display_short)|uniprotkb:Transcription factor IIIC subunit gamma(gene name synonym)|uniprotkb:Transcription factor IIIC 102 kDa subunit(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685757|imex:IM-28774-3127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193703.1|refseq:NP_036218.1|ensembl:ENSG00000119041(gene)|ensembl:ENST00000263956(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039340|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|entrezgene/locuslink:9330(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:cF53nd62xSXQfZerd7bdfB2KUgk9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:NDgMko0ODEPauUG86vfTDC1dmto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UFF9 uniprotkb:P62324 intact:EBI-742299|uniprotkb:O95709|uniprotkb:Q7Z521|uniprotkb:Q9H6Y1|uniprotkb:D3DQI8|uniprotkb:B2RAR8|intact:EBI-10979182|uniprotkb:B0AZS3|uniprotkb:B7Z8R1|ensembl:ENSP00000285896|ensembl:ENSP00000384747|ensembl:ENSP00000430493 intact:EBI-742279|uniprotkb:P31607|ensembl:ENSP00000256015 psi-mi:cnot8_human(display_long)|uniprotkb:CNOT8(gene name)|psi-mi:CNOT8(display_short)|uniprotkb:CALIF(gene name synonym)|uniprotkb:POP2(gene name synonym)|uniprotkb:CCR4-associated factor 8(gene name synonym)|uniprotkb:CAF1-like protein(gene name synonym)|uniprotkb:CAF2(gene name synonym)|uniprotkb:Caf1b(gene name synonym) psi-mi:btg1_human(display_long)|uniprotkb:BTG1(gene name)|psi-mi:BTG1(display_short)|uniprotkb:B-cell translocation gene 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685765|imex:IM-28774-2713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004770.4|refseq:XP_005268584.1|refseq:NP_001288002.1|refseq:NP_001288003.1|refseq:NP_001288004.1|refseq:NP_001288006.1|refseq:NP_001288009.1|refseq:NP_001288011.1|refseq:NP_001288012.1|refseq:NP_001288015.1|refseq:XP_011536008.1|refseq:XP_011536010.1|refseq:XP_016865537.1|refseq:XP_016865538.1|refseq:XP_016865539.1|refseq:XP_016865540.1|refseq:XP_016865541.1|refseq:XP_016865542.1|refseq:XP_016865543.1|refseq:XP_016865544.1|refseq:XP_016865545.1|refseq:XP_016865546.1|ensembl:ENSG00000155508(gene)|ensembl:ENST00000285896(transcript)|ensembl:ENST00000403027(transcript)|ensembl:ENST00000517876(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|mint:Q9UFF9|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-29084N|entrezgene/locuslink:9337(identity) refseq:NP_001722.1|ensembl:ENSG00000133639(gene)|ensembl:ENST00000256015(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006479"(protein methylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033330|interpro:IPR033332|interpro:IPR036054|reactome:R-HSA-9617828|go:"GO:0008285"(negative regulation of cell population proliferation)|entrezgene/locuslink:694(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:pjaQYzYBGJWC7z5R5s8Te+v2sRA9606 rogid:+XRny4AEbQHi+qxKV1Qsf9bOFG09606 rigid:5FqIRBPOcKY3NpkLcNl/0h+5hHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15170 uniprotkb:P17509 intact:EBI-2511314|uniprotkb:Q9UJQ9|intact:EBI-11156070 intact:EBI-741308|ensembl:ENSP00000225648|ensembl:ENSP00000420009|uniprotkb:P09068|uniprotkb:Q9HB11|uniprotkb:Q9UGH2|uniprotkb:A8K835|uniprotkb:D3DTV5 psi-mi:tcal1_human(display_long)|uniprotkb:TCEAL1(gene name)|psi-mi:TCEAL1(display_short)|uniprotkb:SIIR(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein-like 1(gene name synonym)|uniprotkb:Nuclear phosphoprotein p21/SIIR(gene name synonym) psi-mi:hxb6_human(display_long)|uniprotkb:Homeobox protein Hox-2B(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein Hu-2(gene name synonym)|uniprotkb:HOXB6(gene name)|psi-mi:HOXB6(display_short)|uniprotkb:HOX2B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685773|imex:IM-28774-927 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR021156|interpro:IPR010370(Transcription elongation factor A, SII-related)|mint:Q15170|entrezgene/locuslink:9338(identity) go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P17509|ensembl:ENSG00000108511(gene)|ensembl:ENST00000225648(transcript)|ensembl:ENST00000484302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_061825.2|refseq:XP_005257340.1|refseq:XP_005257341.1|entrezgene/locuslink:3216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/11/30 rogid:QGQDFZmacLSo79K+UBfW/ulS32E9606 rogid:5MTUEA03jhudRW4zALviuhMFPPc9606 rigid:qQqOyxRRt7S21NgAUQEj6933ZMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60667 uniprotkb:P28356 intact:EBI-2809270|ensembl:ENSP00000356058|uniprotkb:A8K7J2|uniprotkb:B7Z6Z0|uniprotkb:D9MWM3 intact:EBI-3908736|uniprotkb:Q86ST1|ensembl:ENSP00000249499 psi-mi:faim3_human(display_long)|uniprotkb:FCMR(gene name)|psi-mi:FCMR(display_short)|uniprotkb:FAIM3(gene name synonym)|uniprotkb:IgM Fc fragment receptor(gene name synonym)|uniprotkb:Regulator of Fas-induced apoptosis Toso(gene name synonym)|uniprotkb:TOSO(gene name synonym) psi-mi:hxd9_human(display_long)|uniprotkb:HOXD9(gene name)|psi-mi:HOXD9(display_short)|uniprotkb:HOX4C(gene name synonym)|uniprotkb:Homeobox protein Hox-4C(gene name synonym)|uniprotkb:Homeobox protein Hox-5.2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685645|imex:IM-28774-3563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162894(gene)|ensembl:ENST00000367091(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_001135945.1|refseq:NP_001180267.1|refseq:NP_005440.1|entrezgene/locuslink:9214(identity) refseq:NP_055028.3|ensembl:ENSG00000128709(gene)|ensembl:ENST00000249499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007338"(single fertilization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:3235(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:Yt3zQ0fOJl3PACiIx5FPWFC6eQI9606 rogid:UF3kiWYuTF7+5KyF+u+RuUNSGrY9606 rigid:QVHsejQNLyAt7BjZHlvkRLXrK8c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43513 uniprotkb:P29590 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685869|imex:IM-28774-933 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N|entrezgene/locuslink:5371(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:loWSf951XwPIqzlOCsE3yslU8FI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50458 uniprotkb:Q86U70 intact:EBI-12179869|ensembl:ENSP00000362717|uniprotkb:O95860|uniprotkb:Q52M57|uniprotkb:Q8N1Z3 intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277 psi-mi:lhx2_human(display_long)|uniprotkb:LHX2(gene name)|psi-mi:LHX2(display_short)|uniprotkb:LH2(gene name synonym) psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685781|imex:IM-28774-929 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106689(gene)|ensembl:ENST00000373615(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P50458|reactome:R-HSA-9010553|refseq:NP_004780.3|entrezgene/locuslink:9355(identity) refseq:NP_001106878.1|refseq:NP_003884.1|dip:DIP-31826N|ensembl:ENSG00000198728(gene)|ensembl:ENST00000673968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|reactome:R-HSA-8939236|reactome:R-HSA-9010553|entrezgene/locuslink:8861(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:LgQI6F9VG7krrf3LhrsNGkRkKBc9606 rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606 rigid:Qm23+s70y2LnQBJ1YzszckRZOMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BP71 uniprotkb:Q8BP71 intact:EBI-8821142|ensembl:ENSMUSP00000130739|uniprotkb:Q0R5Z7|uniprotkb:Q0R5Z8|uniprotkb:Q0VH84|uniprotkb:Q537D4|uniprotkb:Q537D5|uniprotkb:Q8BRG0|uniprotkb:Q8R2T5|uniprotkb:Q8VI62|uniprotkb:Q923W8 intact:EBI-8821142|ensembl:ENSMUSP00000130739|uniprotkb:Q0R5Z7|uniprotkb:Q0R5Z8|uniprotkb:Q0VH84|uniprotkb:Q537D4|uniprotkb:Q537D5|uniprotkb:Q8BRG0|uniprotkb:Q8R2T5|uniprotkb:Q8VI62|uniprotkb:Q923W8 psi-mi:rfox2_mouse(display_long)|uniprotkb:Rbfox2(gene name)|psi-mi:Rbfox2(display_short)|uniprotkb:Fox2(gene name synonym)|uniprotkb:Fxh(gene name synonym)|uniprotkb:Hrnbp2(gene name synonym)|uniprotkb:Rbm9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Fox-1 homolog Fxh(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:rfox2_mouse(display_long)|uniprotkb:Rbfox2(gene name)|psi-mi:Rbfox2(display_short)|uniprotkb:Fox2(gene name synonym)|uniprotkb:Fxh(gene name synonym)|uniprotkb:Hrnbp2(gene name synonym)|uniprotkb:Rbm9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Fox-1 homolog Fxh(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685789|imex:IM-28774-2715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273346.1|refseq:NP_001273347.1|refseq:NP_001273348.1|ensembl:ENSMUSG00000033565(gene)|ensembl:ENSMUST00000171751(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR025670|interpro:IPR034237|interpro:IPR035979|mint:Q8BP71|reactome:R-MMU-6803529|refseq:NP_001104297.1|refseq:NP_001104298.1|refseq:NP_001104299.1|refseq:NP_001104300.1|refseq:NP_444334.3|refseq:NP_780596.1|entrezgene/locuslink:93686(identity) refseq:NP_001273346.1|refseq:NP_001273347.1|refseq:NP_001273348.1|ensembl:ENSMUSG00000033565(gene)|ensembl:ENSMUST00000171751(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR025670|interpro:IPR034237|interpro:IPR035979|mint:Q8BP71|reactome:R-MMU-6803529|refseq:NP_001104297.1|refseq:NP_001104298.1|refseq:NP_001104299.1|refseq:NP_001104300.1|refseq:NP_444334.3|refseq:NP_780596.1|entrezgene/locuslink:93686(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:HRi3RnK49EYIZ7cCYmfqcmsudow10090 rogid:HRi3RnK49EYIZ7cCYmfqcmsudow10090 rigid:kaZkLkGh/pAEnvKyVReE8A/8UwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q923E4 uniprotkb:P17919 intact:EBI-1802585|uniprotkb:Q9QXG8|ensembl:ENSMUSP00000020257|ensembl:ENSMUSP00000112595 intact:EBI-26683140|ensembl:ENSMUSP00000019117|uniprotkb:Q3ZAY6|uniprotkb:Q9CYH3 psi-mi:sir1_mouse(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Sir2l1(gene name synonym)|uniprotkb:SIR2alpha(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:hxb1_mouse(display_long)|uniprotkb:Homeobox protein Hox-2.9(gene name synonym)|uniprotkb:Hoxb1(gene name)|psi-mi:Hoxb1(display_short)|uniprotkb:Hox-2.9(gene name synonym)|uniprotkb:Hoxb-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685805|imex:IM-28774-931 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062786.1|dip:DIP-47052N|ensembl:ENSMUSG00000020063(gene)|ensembl:ENSMUST00000020257(transcript)|ensembl:ENSMUST00000120239(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014858"(positive regulation of skeletal muscle cell proliferation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044321"(response to leptin)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0006325"(chromatin organization)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000614"(positive regulation of thyroid-stimulating hormone secretion)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-MMU-3371453|reactome:R-MMU-427359|reactome:R-MMU-9617629|entrezgene/locuslink:93759(identity) ensembl:ENSMUSG00000018973(gene)|ensembl:ENSMUST00000019117(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021546"(rhombomere development)|go:"GO:0021570"(rhombomere 4 development)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021754"(facial nucleus development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|refseq:NP_032292.3|entrezgene/locuslink:15407(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oMEdQHMy6vybdgCwbHeo3au9YHc10090 rogid:a/QkzQGALd4g80HkFKZVR0wLmk010090 rigid:ZYtxNuyXw9fo0xXGMrAcomz2N08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q923E4 uniprotkb:Q05BA5 intact:EBI-1802585|uniprotkb:Q9QXG8|ensembl:ENSMUSP00000020257|ensembl:ENSMUSP00000112595 intact:EBI-5745783|ensembl:ENSMUSP00000085416 psi-mi:sir1_mouse(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Sir2l1(gene name synonym)|uniprotkb:SIR2alpha(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:q05ba5_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685813|imex:IM-28774-1399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062786.1|dip:DIP-47052N|ensembl:ENSMUSG00000020063(gene)|ensembl:ENSMUST00000020257(transcript)|ensembl:ENSMUST00000120239(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014858"(positive regulation of skeletal muscle cell proliferation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044321"(response to leptin)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0006325"(chromatin organization)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000614"(positive regulation of thyroid-stimulating hormone secretion)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-MMU-3371453|reactome:R-MMU-427359|reactome:R-MMU-9617629|entrezgene/locuslink:93759(identity) refseq:NP_032705.2|ensembl:ENSMUSG00000027678(gene)|ensembl:ENSMUST00000088095(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|entrezgene/locuslink:17979(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oMEdQHMy6vybdgCwbHeo3au9YHc10090 rogid:yJS7nFeki1XQGX6CzreuAFSGOxw10090 rigid:+BoBQtabjo5PHonW0RBiizIytko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q923E4 uniprotkb:Q07279 intact:EBI-1802585|uniprotkb:Q9QXG8|ensembl:ENSMUSP00000020257|ensembl:ENSMUSP00000112595 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:sir1_mouse(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Sir2l1(gene name synonym)|uniprotkb:SIR2alpha(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685821|imex:IM-28774-1871 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062786.1|dip:DIP-47052N|ensembl:ENSMUSG00000020063(gene)|ensembl:ENSMUST00000020257(transcript)|ensembl:ENSMUST00000120239(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014858"(positive regulation of skeletal muscle cell proliferation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044321"(response to leptin)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0006325"(chromatin organization)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000614"(positive regulation of thyroid-stimulating hormone secretion)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-MMU-3371453|reactome:R-MMU-427359|reactome:R-MMU-9617629|entrezgene/locuslink:93759(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oMEdQHMy6vybdgCwbHeo3au9YHc10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:nOqPFpn47iV3czRFycRwZWFAIBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q923E4 uniprotkb:Q9WUL8 intact:EBI-1802585|uniprotkb:Q9QXG8|ensembl:ENSMUSP00000020257|ensembl:ENSMUSP00000112595 intact:EBI-26667695|ensembl:ENSMUSP00000092408|uniprotkb:Q66JX0|uniprotkb:Q8R176|uniprotkb:Q9CZV4 psi-mi:sir1_mouse(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:Sirt1(gene name)|psi-mi:Sirt1(display_short)|uniprotkb:Sir2l1(gene name synonym)|uniprotkb:SIR2alpha(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:cite4_mouse(display_long)|uniprotkb:MSG1-related protein 2(gene name synonym)|uniprotkb:Cited4(gene name)|psi-mi:Cited4(display_short)|uniprotkb:Mrg2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685829|imex:IM-28774-3571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062786.1|dip:DIP-47052N|ensembl:ENSMUSG00000020063(gene)|ensembl:ENSMUST00000020257(transcript)|ensembl:ENSMUST00000120239(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014858"(positive regulation of skeletal muscle cell proliferation)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042311"(vasodilation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044321"(response to leptin)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0006325"(chromatin organization)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000614"(positive regulation of thyroid-stimulating hormone secretion)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|reactome:R-MMU-3371453|reactome:R-MMU-427359|reactome:R-MMU-9617629|entrezgene/locuslink:93759(identity) ensembl:ENSMUSG00000070803(gene)|ensembl:ENSMUST00000094814(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007576(CITED)|reactome:R-MMU-8866907|refseq:NP_062509.1|entrezgene/locuslink:56222(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oMEdQHMy6vybdgCwbHeo3au9YHc10090 rogid:0SvgzF+J0ScrJ6drg5QZ4bLEDVc10090 rigid:QAjWGX4EDIGxOXlFv2gBkDV+8hI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PGB8 uniprotkb:Q61545 intact:EBI-11786213|uniprotkb:B1AUP6|uniprotkb:B1AUP7|uniprotkb:Q8BSS1|uniprotkb:Q91Y58|ensembl:ENSMUSP00000076769|ensembl:ENSMUSP00000086366 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:smca1_mouse(display_long)|uniprotkb:Smarca1(gene name)|psi-mi:Smarca1(display_short)|uniprotkb:Snf2l(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:DNA-dependent ATPase SNF2L(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685837|imex:IM-28774-3129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277637.1|refseq:NP_444353.3|ensembl:ENSMUSG00000031099(gene)|ensembl:ENSMUST00000077569(transcript)|ensembl:ENSMUST00000088973(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007420"(brain development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090537"(CERF complex)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|go:"GO:0070615"|entrezgene/locuslink:93761(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:l5sQ6pnpV9qrjwDLn2ttgTgqodk10090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:F7Qn8lSxIFDeIlDHmjDc958cJBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91ZW3 uniprotkb:P50540 intact:EBI-927547|uniprotkb:Q8C791|uniprotkb:Q8CA22|uniprotkb:Q8VDG1|uniprotkb:Q925M9|ensembl:ENSMUSP00000044361 intact:EBI-2942734|ensembl:ENSMUSP00000107366 psi-mi:smca5_mouse(display_long)|uniprotkb:Smarca5(gene name)|psi-mi:Smarca5(display_short)|uniprotkb:Snf2h(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:mxi1_mouse(display_long)|uniprotkb:Mxi1(gene name)|psi-mi:Mxi1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685845|imex:IM-28774-2717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444354.2|dip:DIP-36073N|ensembl:ENSMUSG00000031715(gene)|ensembl:ENSMUST00000043359(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:Q91ZW3|reactome:R-MMU-5250924|reactome:R-MMU-5693565|reactome:R-MMU-606279|entrezgene/locuslink:93762(identity) ensembl:ENSMUSG00000025025(gene)|ensembl:ENSMUST00000111737(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001008543.1|refseq:NP_034977.1|refseq:XP_006526801.1|refseq:XP_006526802.1|refseq:XP_006526803.1|dip:DIP-489N|entrezgene/locuslink:17859(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:+HXPfdDGqKssFXooxGP7gM+u8Oc10090 rogid:u+6aVUTmurbc29xWDImnklKUIrg10090 rigid:EVBG3ekGTK3pFgj+xNuqu4UEc8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13503 uniprotkb:P14373 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685853|imex:IM-28774-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N|entrezgene/locuslink:9412(identity) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rigid:8rSGXT9ZVU+YQo37D8mCUN3nSto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13503 uniprotkb:Q15633 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685861|imex:IM-28774-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N|entrezgene/locuslink:9412(identity) ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N|entrezgene/locuslink:6895(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:KaC7IMZtxybv2TM13M4QQ6hQsW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43513 uniprotkb:Q8N653 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685877|imex:IM-28774-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:MghRPH1Y4Z84/Hd63p81YuH7ol0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43513 uniprotkb:Q9Y6K9 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685885|imex:IM-28774-3131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|entrezgene/locuslink:9443(identity) refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 rigid:uFCKER7DnkLadkZjbYqa3+SQQrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:Q01844 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685893|imex:IM-28774-2293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity) refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N|entrezgene/locuslink:2130(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:JpshEg2nZFneviZzug6aEGFerYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:P61457 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685901|imex:IM-28774-3133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity) refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:WdJZf9rU/V3FEooIlOHEbdeJCvY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:Q3USK5 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-26685909|ensembl:ENSMUSP00000159359 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:q3usk5_mouse(display_long)|uniprotkb:Tead1(gene name)|psi-mi:Tead1(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685928|imex:IM-28774-3135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) ensembl:ENSMUSG00000055320(gene)|ensembl:ENSMUST00000239442(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0035329"(hippo signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR038096|interpro:IPR041086|refseq:NP_001160056.1|refseq:NP_001160057.1|refseq:NP_033372.1|entrezgene/locuslink:21676(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:rfJG/u0cg6mizjDdRjbl9H7+i7c10090 rigid:V10+XxeDF+YmudH9eKxxJkrtaYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:P48301 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-26685936|ensembl:ENSMUSP00000033060|ensembl:ENSMUSP00000103431|uniprotkb:Q62297 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:tead2_mouse(display_long)|uniprotkb:ETEF-1(gene name synonym)|uniprotkb:Embryonic TEA domain-containing factor(gene name synonym)|uniprotkb:TEA domain family member 2(gene name synonym)|uniprotkb:Tead2(gene name)|psi-mi:Tead2(display_short)|uniprotkb:Etdf(gene name synonym)|uniprotkb:Etf(gene name synonym)|uniprotkb:Tef4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26685986|imex:IM-28774-2295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) ensembl:ENSMUSG00000030796(gene)|ensembl:ENSMUST00000033060(transcript)|ensembl:ENSMUST00000107801(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030903"(notochord development)|go:"GO:0035329"(hippo signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR038096|interpro:IPR041086|reactome:R-MMU-2032785|reactome:R-MMU-8951671|refseq:NP_001272427.1|refseq:NP_035695.1|refseq:XP_006540840.1|entrezgene/locuslink:21677(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:oHSMV1vEXWl/Wonm38UY8sfyRPU10090 rigid:Td5rkSOlprRMjLMya7KdGD/NDdo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:P70210 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-26685994|ensembl:ENSMUSP00000115443|ensembl:ENSMUSP00000118582|uniprotkb:O08516|uniprotkb:O70623|uniprotkb:P70209 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:tead3_mouse(display_long)|uniprotkb:DTEF-1(gene name synonym)|uniprotkb:ETF-related factor 1(gene name synonym)|uniprotkb:TEA domain family member 3(gene name synonym)|uniprotkb:Tead3(gene name)|psi-mi:Tead3(display_short)|uniprotkb:Tcf13r2(gene name synonym)|uniprotkb:Tef5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686025|imex:IM-28774-2297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) ensembl:ENSMUSG00000002249(gene)|ensembl:ENSMUST00000154873(transcript)|ensembl:ENSMUST00000156862(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035329"(hippo signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027253|interpro:IPR038096|interpro:IPR041086|reactome:R-MMU-2032785|reactome:R-MMU-8951671|refseq:NP_001091696.2|refseq:NP_001191085.1|refseq:NP_035696.3|entrezgene/locuslink:21678(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:me5udduXCbmlJQOejH0w0wfJl6810090 rigid:w6dVoM+JxC+e8UnMMcypTjfjfjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61216 uniprotkb:Q99JX1 intact:EBI-309424|uniprotkb:Q3TVE8|ensembl:ENSMUSP00000121346 intact:EBI-309427|uniprotkb:Q3UZH1|uniprotkb:Q9CT98|ensembl:ENSMUSP00000025057|ensembl:ENSMUSP00000110498 psi-mi:taf13_mouse(display_long)|uniprotkb:Taf13(gene name)|psi-mi:Taf13(display_short)|uniprotkb:Taf2k(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 18 kDa subunit(gene name synonym) psi-mi:taf11_mouse(display_long)|uniprotkb:Taf11(gene name)|psi-mi:Taf11(display_short)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit(gene name synonym)|uniprotkb:TFIID subunit p30-beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686201|imex:IM-28774-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079720.1|ensembl:ENSMUSG00000048100(gene)|ensembl:ENSMUST00000143054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:99730(identity) refseq:NP_081112.1|refseq:XP_006524924.1|refseq:XP_006524925.1|ensembl:ENSMUSG00000024218(gene)|ensembl:ENSMUST00000025057(transcript)|ensembl:ENSMUST00000114848(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|refseq:XP_011244890.1|entrezgene/locuslink:68776(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7pXO1SLH76kWulpTOtxekJGU8ac10090 rogid:havjjYpTtTuEpGBSTQr76x7j6TY10090 rigid:UamWLfiu/HIK6RkzvC/GewE9PfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:Q8CFD5 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686049|imex:IM-28774-3573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rigid:F90ZqGQbSn89mPqxzLkR3qADE2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q3 uniprotkb:Q16531 intact:EBI-3649340|uniprotkb:B3KNE1|uniprotkb:Q9H1F1|ensembl:ENSP00000362410 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:mafb_human(display_long)|uniprotkb:MAFB(gene name)|psi-mi:MAFB(display_short)|uniprotkb:KRML(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686137|imex:IM-28774-1875 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005452.2|ensembl:ENSP00000362410|ensembl:ENSG00000204103(gene)|ensembl:ENST00000373313(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|mint:Q9Y5Q3|reactome:R-HSA-5617472|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007423"(sensory organ development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:9935(identity) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N|entrezgene/locuslink:1642(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0TC5DeljJqY/ClydzzdvMScyhzI9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:b9/7Y0iRgvqWd2pWZMZpaK6U8bo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKV0 uniprotkb:Q06413 intact:EBI-765444|uniprotkb:O94845|uniprotkb:O95028|uniprotkb:Q2M2R6|uniprotkb:Q86SL1|uniprotkb:Q86US3|uniprotkb:A7E2F3|uniprotkb:B7Z917|uniprotkb:B7Z4I4|uniprotkb:B7Z928|uniprotkb:B7Z940|uniprotkb:C9JS87|uniprotkb:E7EX34|uniprotkb:F8W9E0|intact:EBI-28970749|ensembl:ENSP00000410337 intact:EBI-2684075|uniprotkb:D7F7N5|uniprotkb:F8W7V7|uniprotkb:C9JMZ0|ensembl:ENSP00000396219|ensembl:ENSP00000421925|ensembl:ENSP00000490473 psi-mi:hdac9_human(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:HDAC9(gene name)|psi-mi:HDAC9(display_short)|uniprotkb:HDAC7(gene name synonym)|uniprotkb:HDAC7B(gene name synonym)|uniprotkb:KIAA0744(gene name synonym)|uniprotkb:HDRP(gene name synonym)|uniprotkb:MITR(gene name synonym) psi-mi:mef2c_human(display_long)|uniprotkb:MEF2C(gene name)|psi-mi:MEF2C(display_short)|uniprotkb:Myocyte enhancer factor 2C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686065|imex:IM-28774-3575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308818.1|ensembl:ENST00000441542|ensembl:ENSP00000408617|ensembl:ENST00000456174|ensembl:ENSP00000388568|ensembl:ENST00000524023|ensembl:ENSP00000430036|ensembl:ENST00000401921|ensembl:ENSP00000383912|ensembl:ENST00000405010|ensembl:ENSP00000384382|ensembl:ENST00000406451|ensembl:ENSP00000384657|ensembl:ENST00000417496|ensembl:ENSP00000401669|ensembl:ENST00000428307|ensembl:ENSP00000395655|ensembl:ENSP00000410337|refseq:NP_848510.1|refseq:NP_848512.1|refseq:NP_001191073.1|refseq:NP_001191074.1|refseq:NP_001191075.1|refseq:NP_001191076.1|refseq:NP_001191077.1|refseq:NP_055522.1|refseq:NP_478056.1|refseq:XP_016868315.1|refseq:XP_016868317.1|refseq:XP_011513940.1|refseq:XP_011513941.1|refseq:NP_001308797.1|refseq:NP_001308798.1|refseq:NP_001308799.1|refseq:NP_001308800.1|refseq:NP_001308801.1|refseq:NP_001308802.1|refseq:NP_001308803.1|refseq:NP_001308804.1|refseq:NP_001308805.1|refseq:NP_001308806.1|refseq:NP_001308807.1|refseq:NP_001308808.1|refseq:NP_001308813.1|refseq:NP_001308814.1|refseq:NP_001308815.1|refseq:NP_001308816.1|refseq:NP_001308817.1|refseq:NP_001308819.1|refseq:NP_001308820.1|refseq:NP_001308822.1|refseq:NP_001308823.1|refseq:NP_001308824.1|refseq:NP_001308825.1|refseq:NP_001308826.1|refseq:NP_001308827.1|refseq:NP_001308828.1|refseq:NP_001308829.1|refseq:NP_001308830.1|refseq:NP_001308831.1|dip:DIP-39904N|ensembl:ENSG00000048052(gene)|ensembl:ENST00000432645(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|mint:Q9UKV0|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|entrezgene/locuslink:9734(identity) refseq:XP_011541702.1|refseq:XP_011541698.1|refseq:NP_001294931.1|refseq:NP_001124477.1|refseq:NP_001180276.1|refseq:NP_001180277.1|refseq:NP_001180278.1|refseq:NP_001180279.1|refseq:NP_002388.2|refseq:XP_005248568.1|refseq:XP_006714682.1|refseq:XP_006714688.1|refseq:XP_016864967.1|refseq:XP_016864968.1|refseq:XP_016864969.1|refseq:XP_016864970.1|dip:DIP-40857N|refseq:XP_016864965.1|refseq:XP_016864966.1|ensembl:ENSG00000081189(gene)|ensembl:ENST00000437473(transcript)|ensembl:ENST00000504921(transcript)|ensembl:ENST00000636294(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003185"(sinoatrial valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048666"(neuron development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007611"(learning or memory)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q06413|reactome:R-HSA-198753|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9022707|reactome:R-HSA-9707616|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|entrezgene/locuslink:4208(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oFAc6CP+RY58lEB4qPxWnM90ecg9606 rogid:vZxaYdzMYwHDAZZItu8N7SWZPic9606 rigid:LOZ4SrKk53+RGSRA4Q5yJG9PV4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61216 uniprotkb:Q99JX1 intact:EBI-309424|uniprotkb:Q3TVE8|ensembl:ENSMUSP00000121346 intact:EBI-309427|uniprotkb:Q3UZH1|uniprotkb:Q9CT98|ensembl:ENSMUSP00000025057|ensembl:ENSMUSP00000110498 psi-mi:taf13_mouse(display_long)|uniprotkb:Taf13(gene name)|psi-mi:Taf13(display_short)|uniprotkb:Taf2k(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 18 kDa subunit(gene name synonym) psi-mi:taf11_mouse(display_long)|uniprotkb:Taf11(gene name)|psi-mi:Taf11(display_short)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit(gene name synonym)|uniprotkb:TFIID subunit p30-beta(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686193|imex:IM-28774-1419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079720.1|ensembl:ENSMUSG00000048100(gene)|ensembl:ENSMUST00000143054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:99730(identity) refseq:NP_081112.1|refseq:XP_006524924.1|refseq:XP_006524925.1|ensembl:ENSMUSG00000024218(gene)|ensembl:ENSMUST00000025057(transcript)|ensembl:ENSMUST00000114848(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|refseq:XP_011244890.1|entrezgene/locuslink:68776(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7pXO1SLH76kWulpTOtxekJGU8ac10090 rogid:havjjYpTtTuEpGBSTQr76x7j6TY10090 rigid:UamWLfiu/HIK6RkzvC/GewE9PfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61216 uniprotkb:P29037 intact:EBI-309424|uniprotkb:Q3TVE8|ensembl:ENSMUSP00000121346 intact:EBI-4399956|uniprotkb:O09169|uniprotkb:Q80UL8|uniprotkb:Q8C3S1|ensembl:ENSMUSP00000014911|ensembl:ENSMUSP00000112794|ensembl:ENSMUSP00000124317 psi-mi:taf13_mouse(display_long)|uniprotkb:Taf13(gene name)|psi-mi:Taf13(display_short)|uniprotkb:Taf2k(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 18 kDa subunit(gene name synonym) psi-mi:tbp_mouse(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:Tfiid(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686185|imex:IM-28774-1879 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079720.1|ensembl:ENSMUSG00000048100(gene)|ensembl:ENSMUST00000143054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:99730(identity) refseq:NP_038712.3|dip:DIP-24197N|ensembl:ENSMUSG00000014767(gene)|ensembl:ENSMUST00000014911(transcript)|ensembl:ENSMUST00000117593(transcript)|ensembl:ENSMUST00000162505(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045120"(pronucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-MMU-5250924|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-9018519|entrezgene/locuslink:21374(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7pXO1SLH76kWulpTOtxekJGU8ac10090 rogid:Rv5vNIOGEhlaWS1woZqBFiuf5pg10090 rigid:9B18ISr9yJGcgEIf+51kMrVn62w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61216 uniprotkb:P23812 intact:EBI-309424|uniprotkb:Q3TVE8|ensembl:ENSMUSP00000121346 intact:EBI-925295|uniprotkb:Q8BSN0|ensembl:ENSMUSP00000001878 psi-mi:taf13_mouse(display_long)|uniprotkb:Taf13(gene name)|psi-mi:Taf13(display_short)|uniprotkb:Taf2k(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 18 kDa subunit(gene name synonym) psi-mi:hxd12_mouse(display_long)|uniprotkb:Hoxd12(gene name)|psi-mi:Hoxd12(display_short)|uniprotkb:Hox-4.7(gene name synonym)|uniprotkb:Hoxd-12(gene name synonym)|uniprotkb:Homeobox protein Hox-4.7(gene name synonym)|uniprotkb:Homeobox protein Hox-5.6(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686177|imex:IM-28774-2719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079720.1|ensembl:ENSMUSG00000048100(gene)|ensembl:ENSMUST00000143054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:99730(identity) refseq:NP_032300.2|ensembl:ENSMUSG00000001823(gene)|ensembl:ENSMUST00000001878(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007389"(pattern specification process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|entrezgene/locuslink:15432(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7pXO1SLH76kWulpTOtxekJGU8ac10090 rogid:9sYNBvbWXP/t58XCNKhh0VCRxQY10090 rigid:XAFCJYXBzAnK5aKOsCxEnWmi1Fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BX22 uniprotkb:Q9QY14 intact:EBI-2312582|uniprotkb:A2AV00|uniprotkb:Q6S7E8|uniprotkb:Q6S7E9|uniprotkb:Q7TST6|ensembl:ENSMUSP00000029061 intact:EBI-26677604|ensembl:ENSMUSP00000050445 psi-mi:sall4_mouse(display_long)|uniprotkb:Sall4(gene name)|psi-mi:Sall4(display_short)|uniprotkb:Zinc finger protein SALL4(gene name synonym) psi-mi:foxe3_mouse(display_long)|uniprotkb:Foxe3(gene name)|psi-mi:Foxe3(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686169|imex:IM-28774-3157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_780512.2|refseq:NP_958797.2|refseq:NP_958798.2|dip:DIP-29926N|ensembl:ENSMUSG00000027547(gene)|ensembl:ENSMUST00000029061(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009888"(tissue development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021915"(neural tube development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BX22|reactome:R-MMU-8943724|entrezgene/locuslink:99377(identity) ensembl:ENSMUSG00000044518(gene)|ensembl:ENSMUST00000050940(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002930"(trabecular meshwork development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048468"(cell development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:2001111"(positive regulation of lens epithelial cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_056573.1|entrezgene/locuslink:30923(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:84RTcgupqeb0ypojGiwpAezUWVw10090 rogid:IPEp/88wZJBwBcPmnFjAJzkpGSU10090 rigid:hiz+Lre3S9slmpHgWp+aHR7s8Js false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BX22 uniprotkb:Q08624 intact:EBI-2312582|uniprotkb:A2AV00|uniprotkb:Q6S7E8|uniprotkb:Q6S7E9|uniprotkb:Q7TST6|ensembl:ENSMUSP00000029061 intact:EBI-26668976|ensembl:ENSMUSP00000097740 psi-mi:sall4_mouse(display_long)|uniprotkb:Sall4(gene name)|psi-mi:Sall4(display_short)|uniprotkb:Zinc finger protein SALL4(gene name synonym) psi-mi:hxc4_mouse(display_long)|uniprotkb:Homeobox protein Hox-3.5(gene name synonym)|uniprotkb:Hoxc4(gene name)|psi-mi:Hoxc4(display_short)|uniprotkb:Hox-3.5(gene name synonym)|uniprotkb:Hoxc-4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686161|imex:IM-28774-1877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_780512.2|refseq:NP_958797.2|refseq:NP_958798.2|dip:DIP-29926N|ensembl:ENSMUSG00000027547(gene)|ensembl:ENSMUST00000029061(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009888"(tissue development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021915"(neural tube development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BX22|reactome:R-MMU-8943724|entrezgene/locuslink:99377(identity) ensembl:ENSMUSG00000075394(gene)|ensembl:ENSMUST00000100164(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1904840"(positive regulation of male germ-line stem cell asymmetric division)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|refseq:NP_038581.2|refseq:XP_006520524.1|refseq:XP_006520525.1|refseq:XP_006520526.1|refseq:XP_011243762.1|entrezgene/locuslink:15423(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:84RTcgupqeb0ypojGiwpAezUWVw10090 rogid:ghNLyc14ASxPaO2NvU1XetoiRU410090 rigid:lQ/ZbT5dNZTzmVbd/jg/J3pRkSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5Q3 uniprotkb:Q9Y5Q3 intact:EBI-3649340|uniprotkb:B3KNE1|uniprotkb:Q9H1F1|ensembl:ENSP00000362410 intact:EBI-3649340|uniprotkb:B3KNE1|uniprotkb:Q9H1F1|ensembl:ENSP00000362410 psi-mi:mafb_human(display_long)|uniprotkb:MAFB(gene name)|psi-mi:MAFB(display_short)|uniprotkb:KRML(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:mafb_human(display_long)|uniprotkb:MAFB(gene name)|psi-mi:MAFB(display_short)|uniprotkb:KRML(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686145|imex:IM-28774-3139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005452.2|ensembl:ENSP00000362410|ensembl:ENSG00000204103(gene)|ensembl:ENST00000373313(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|mint:Q9Y5Q3|reactome:R-HSA-5617472|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007423"(sensory organ development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:9935(identity) refseq:NP_005452.2|ensembl:ENSP00000362410|ensembl:ENSG00000204103(gene)|ensembl:ENST00000373313(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|mint:Q9Y5Q3|reactome:R-HSA-5617472|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007423"(sensory organ development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:9935(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:0TC5DeljJqY/ClydzzdvMScyhzI9606 rogid:0TC5DeljJqY/ClydzzdvMScyhzI9606 rigid:UPDpr9cIkZTLV5xFFNqeYMUfVjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15062 uniprotkb:P37231 intact:EBI-722671|ensembl:ENSP00000307604 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:zbtb5_human(display_long)|uniprotkb:ZBTB5(gene name)|psi-mi:ZBTB5(display_short)|uniprotkb:KIAA0354(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686129|imex:IM-28774-2319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055687.1|refseq:XP_005251691.1|dip:DIP-41566N|ensembl:ENSG00000168795(gene)|ensembl:ENST00000307750(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O15062|entrezgene/locuslink:9925(identity) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707|entrezgene/locuslink:5468(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:snw/pD42fIJp5zlezPU76fP1jZc9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rigid:EPE3ZiuvR0QF1DRxBZAX1OHoZsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q924Z4 uniprotkb:Q9EPK5 intact:EBI-8369833|uniprotkb:Q3TXC5|uniprotkb:Q9DCN6|intact:MINT-1851988|ensembl:ENSMUSP00000015858 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 psi-mi:cers2_mouse(display_long)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 3(gene name synonym)|uniprotkb:Trh3(gene name synonym)|uniprotkb:Cers2(gene name)|psi-mi:Cers2(display_short)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Lass2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym) psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686057|imex:IM-28774-1873 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084065.1|refseq:XP_006502323.1|refseq:NP_001307421.1|ensembl:ENSMUSG00000015714(gene)|ensembl:ENSMUST00000015858(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q924Z4|reactome:R-MMU-1660661|entrezgene/locuslink:76893(identity) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) - comment:mint|function:Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:13Sv+4Gn8ItMCO9eykQGyy3C8NY10090 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rigid:QjmYs3/VQPcrCaoxd3WtipiUclk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HBZ2 uniprotkb:Q99814 intact:EBI-765971|uniprotkb:O15024|uniprotkb:Q8IYC2|uniprotkb:B4DIS7|ensembl:ENSP00000307479 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 psi-mi:arnt2_human(display_long)|uniprotkb:ARNT2(gene name)|psi-mi:ARNT2(display_short)|uniprotkb:KIAA0307(gene name synonym)|uniprotkb:BHLHE1(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 1(gene name synonym) psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686121|imex:IM-28774-3579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055677.3|ensembl:ENSG00000172379(gene)|ensembl:ENST00000303329(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR035965|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR036638|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|entrezgene/locuslink:9915(identity) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|entrezgene/locuslink:2034(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:nXUG8CAT3vm2UZictlc3M86O/Uw9606 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rigid:bx1Aen42VL7ws36S3Gh/ojEZ1g0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3THK3 uniprotkb:Q00322 intact:EBI-8391657|intact:MINT-4119252|uniprotkb:Q8R5B7|ensembl:ENSMUSP00000002733 intact:EBI-15611593|ensembl:ENSMUSP00000148145|uniprotkb:Q3U937|uniprotkb:Q8BW92 psi-mi:t2fa_mouse(display_long)|uniprotkb:Gtf2f1(gene name)|psi-mi:Gtf2f1(display_short)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym) psi-mi:cebpd_mouse(display_long)|uniprotkb:C/EBP-related protein 3(gene name synonym)|uniprotkb:Cebpd(gene name)|psi-mi:Cebpd(display_short)|uniprotkb:Crp3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686113|imex:IM-28774-3137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_598562.1|ensembl:ENSMUSG00000002658(gene)|ensembl:ENSMUST00000002733(transcript)|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:Q3THK3|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|entrezgene/locuslink:98053(identity) ensembl:ENSMUSG00000071637(gene)|ensembl:ENSMUST00000096232(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|refseq:NP_031705.3|dip:DIP-41645N|entrezgene/locuslink:12609(identity) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:vdOcr1HiWr0f2e3FJyT2bhyG6SA10090 rogid:aCmCPifzzDnsat5YKja5onlnM6E10090 rigid:0QQFD8KZUPXGtYc/3u+x3UWiG3w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q04724 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686105|imex:IM-28774-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N|entrezgene/locuslink:7088(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:89p4aZnun0KY8mkguEOPQMBivw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:P42226 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-1186478|uniprotkb:Q5FBW5|uniprotkb:Q71UP4|uniprotkb:A8K316|uniprotkb:B7ZA27|uniprotkb:F5GXI9|intact:EBI-28971408|ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENSP00000438451|ensembl:ENSP00000451742 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:stat6_human(display_long)|uniprotkb:IL-4 Stat(gene name synonym)|uniprotkb:STAT6(gene name)|psi-mi:STAT6(display_short) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686097|imex:IM-28774-937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity) ensembl:ENSP00000300134|ensembl:ENSP00000401486|ensembl:ENST00000537215|ensembl:ENSP00000444530|ensembl:ENST00000538913|ensembl:ENSP00000445409|ensembl:ENSP00000438451|ensembl:ENSP00000451742|refseq:NP_001171549.1|refseq:NP_001171550.1|refseq:NP_003144.3|refseq:XP_006719638.1|refseq:NP_001171551.1|ensembl:ENSG00000166888(gene)|ensembl:ENST00000300134(transcript)|ensembl:ENST00000454075(transcript)|ensembl:ENST00000543873(transcript)|ensembl:ENST00000556155(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060443"(mammary gland morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR028187|interpro:IPR035857|interpro:IPR036535|interpro:IPR036860|mint:P42226|rcsb pdb:1OJ5|rcsb pdb:4Y5U|rcsb pdb:4Y5W|rcsb pdb:5D39|rcsb pdb:5NWM|rcsb pdb:5NWX|reactome:R-HSA-186763|reactome:R-HSA-3249367|reactome:R-HSA-6785807|dip:DIP-39855N|entrezgene/locuslink:6778(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:BuSBP6PMmA3hcOmnaH3/r4XoiVw9606 rigid:ncbWdnmI7wU+g6k7kBissMaEL5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P56524 uniprotkb:Q8N653 intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686089|imex:IM-28774-3577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|entrezgene/locuslink:9759(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EJhE8LikofmF9H8ubNsola4pSpc9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:EZW8lSCMB3EUJMKM72vpcAT4iAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P56524 uniprotkb:Q8N653 intact:EBI-308629|uniprotkb:Q9UND6|uniprotkb:E9PGB9|uniprotkb:F5GX36|uniprotkb:Q86YH7|intact:EBI-28970476|ensembl:ENSP00000264606 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 psi-mi:hdac4_human(display_long)|uniprotkb:HDAC4(gene name)|psi-mi:HDAC4(display_short)|uniprotkb:KIAA0288(gene name synonym) psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686081|imex:IM-28774-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264606|ensembl:ENSG00000068024(gene)|ensembl:ENST00000345617(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031672"(A band)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042113"(B cell activation)|go:"GO:0042493"|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR033660|interpro:IPR037138|mint:P56524|rcsb pdb:2H8N|rcsb pdb:2O94|rcsb pdb:2VQJ|rcsb pdb:2VQM|rcsb pdb:2VQO|rcsb pdb:2VQQ|rcsb pdb:2VQV|rcsb pdb:2VQW|rcsb pdb:3UXG|rcsb pdb:3UZD|rcsb pdb:3V31|rcsb pdb:4CBT|rcsb pdb:4CBY|rcsb pdb:5A2S|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6FYZ|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-8941284|reactome:R-HSA-8951936|refseq:NP_006028.2|dip:DIP-34565N|entrezgene/locuslink:9759(identity) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|entrezgene/locuslink:8216(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:EJhE8LikofmF9H8ubNsola4pSpc9606 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rigid:EZW8lSCMB3EUJMKM72vpcAT4iAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKV0 uniprotkb:Q06413 intact:EBI-765444|uniprotkb:O94845|uniprotkb:O95028|uniprotkb:Q2M2R6|uniprotkb:Q86SL1|uniprotkb:Q86US3|uniprotkb:A7E2F3|uniprotkb:B7Z917|uniprotkb:B7Z4I4|uniprotkb:B7Z928|uniprotkb:B7Z940|uniprotkb:C9JS87|uniprotkb:E7EX34|uniprotkb:F8W9E0|intact:EBI-28970749|ensembl:ENSP00000410337 intact:EBI-2684075|uniprotkb:D7F7N5|uniprotkb:F8W7V7|uniprotkb:C9JMZ0|ensembl:ENSP00000396219|ensembl:ENSP00000421925|ensembl:ENSP00000490473 psi-mi:hdac9_human(display_long)|uniprotkb:Histone deacetylase 7B(gene name synonym)|uniprotkb:Histone deacetylase-related protein(gene name synonym)|uniprotkb:MEF2-interacting transcription repressor MITR(gene name synonym)|uniprotkb:HDAC9(gene name)|psi-mi:HDAC9(display_short)|uniprotkb:HDAC7(gene name synonym)|uniprotkb:HDAC7B(gene name synonym)|uniprotkb:KIAA0744(gene name synonym)|uniprotkb:HDRP(gene name synonym)|uniprotkb:MITR(gene name synonym) psi-mi:mef2c_human(display_long)|uniprotkb:MEF2C(gene name)|psi-mi:MEF2C(display_short)|uniprotkb:Myocyte enhancer factor 2C(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686073|imex:IM-28774-1417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308818.1|ensembl:ENST00000441542|ensembl:ENSP00000408617|ensembl:ENST00000456174|ensembl:ENSP00000388568|ensembl:ENST00000524023|ensembl:ENSP00000430036|ensembl:ENST00000401921|ensembl:ENSP00000383912|ensembl:ENST00000405010|ensembl:ENSP00000384382|ensembl:ENST00000406451|ensembl:ENSP00000384657|ensembl:ENST00000417496|ensembl:ENSP00000401669|ensembl:ENST00000428307|ensembl:ENSP00000395655|ensembl:ENSP00000410337|refseq:NP_848510.1|refseq:NP_848512.1|refseq:NP_001191073.1|refseq:NP_001191074.1|refseq:NP_001191075.1|refseq:NP_001191076.1|refseq:NP_001191077.1|refseq:NP_055522.1|refseq:NP_478056.1|refseq:XP_016868315.1|refseq:XP_016868317.1|refseq:XP_011513940.1|refseq:XP_011513941.1|refseq:NP_001308797.1|refseq:NP_001308798.1|refseq:NP_001308799.1|refseq:NP_001308800.1|refseq:NP_001308801.1|refseq:NP_001308802.1|refseq:NP_001308803.1|refseq:NP_001308804.1|refseq:NP_001308805.1|refseq:NP_001308806.1|refseq:NP_001308807.1|refseq:NP_001308808.1|refseq:NP_001308813.1|refseq:NP_001308814.1|refseq:NP_001308815.1|refseq:NP_001308816.1|refseq:NP_001308817.1|refseq:NP_001308819.1|refseq:NP_001308820.1|refseq:NP_001308822.1|refseq:NP_001308823.1|refseq:NP_001308824.1|refseq:NP_001308825.1|refseq:NP_001308826.1|refseq:NP_001308827.1|refseq:NP_001308828.1|refseq:NP_001308829.1|refseq:NP_001308830.1|refseq:NP_001308831.1|dip:DIP-39904N|ensembl:ENSG00000048052(gene)|ensembl:ENST00000432645(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042113"(B cell activation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0051153"(regulation of striated muscle cell differentiation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990678"(histone H4-K16 deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017320(Histone deacetylase class II, eukaryotic)|interpro:IPR023696|interpro:IPR023801|interpro:IPR024643|interpro:IPR037138|mint:Q9UKV0|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|entrezgene/locuslink:9734(identity) refseq:XP_011541702.1|refseq:XP_011541698.1|refseq:NP_001294931.1|refseq:NP_001124477.1|refseq:NP_001180276.1|refseq:NP_001180277.1|refseq:NP_001180278.1|refseq:NP_001180279.1|refseq:NP_002388.2|refseq:XP_005248568.1|refseq:XP_006714682.1|refseq:XP_006714688.1|refseq:XP_016864967.1|refseq:XP_016864968.1|refseq:XP_016864969.1|refseq:XP_016864970.1|dip:DIP-40857N|refseq:XP_016864965.1|refseq:XP_016864966.1|ensembl:ENSG00000081189(gene)|ensembl:ENST00000437473(transcript)|ensembl:ENST00000504921(transcript)|ensembl:ENST00000636294(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003185"(sinoatrial valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035690"|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048666"(neuron development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0007611"(learning or memory)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000987"(positive regulation of behavioral fear response)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|mint:Q06413|reactome:R-HSA-198753|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-525793|reactome:R-HSA-9022707|reactome:R-HSA-9707616|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|entrezgene/locuslink:4208(identity) - - - figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:oFAc6CP+RY58lEB4qPxWnM90ecg9606 rogid:vZxaYdzMYwHDAZZItu8N7SWZPic9606 rigid:LOZ4SrKk53+RGSRA4Q5yJG9PV4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:Q62296 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-9253444|uniprotkb:A2BDD5|uniprotkb:P70282|uniprotkb:Q61174|uniprotkb:Q61175|uniprotkb:Q62298|ensembl:ENSMUSP00000006311 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:tead4_mouse(display_long)|uniprotkb:Tead4(gene name)|psi-mi:Tead4(display_short)|uniprotkb:Tcf13r1(gene name synonym)|uniprotkb:Tef3(gene name synonym)|uniprotkb:Tefr1(gene name synonym)|uniprotkb:ETF-related factor 2(gene name synonym)|uniprotkb:TEA domain family member 4(gene name synonym)|uniprotkb:TEF-1-related factor 1(gene name synonym)|uniprotkb:TEF-1-related factor FR-19(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686033|imex:IM-28774-2299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) refseq:NP_001074448.2|refseq:NP_035697.3|dip:DIP-59847N|ensembl:ENSMUSG00000030353(gene)|ensembl:ENSMUST00000006311(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001825"(blastocyst formation)|go:"GO:0001830"(trophectodermal cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007566"(embryo implantation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR027255|interpro:IPR038096|interpro:IPR041086|rcsb pdb:3JUA|rcsb pdb:4LN0|rcsb pdb:5GN0|rcsb pdb:5XJD|rcsb pdb:5Z2Q|rcsb pdb:6L9F|rcsb pdb:6SBA|reactome:R-MMU-2032785|reactome:R-MMU-8951671|entrezgene/locuslink:21679(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:AsL1gpxJ7abeFVwJyF1xUkc8Q2c10090 rigid:L9oSWVdY7hzes7QC8LR2FV6adtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:Q9D6K9 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-26682068|ensembl:ENSMUSP00000023762|uniprotkb:Q3UL17|uniprotkb:Q80YB2|uniprotkb:Q8BPH6|uniprotkb:Q921T8|uniprotkb:Q924Z3 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:cers5_mouse(display_long)|uniprotkb:LAG1 longevity assurance homolog 5(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS5(gene name synonym)|uniprotkb:Translocating chain-associating membrane protein homolog 4(gene name synonym)|uniprotkb:Cers5(gene name)|psi-mi:Cers5(display_short)|uniprotkb:Lass5(gene name synonym)|uniprotkb:Trh4(gene name synonym)|uniprotkb:Sphingoid base N-palmitoyltransferase CERS5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686041|imex:IM-28774-935 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|entrezgene/locuslink:97064(identity) ensembl:ENSMUSG00000023021(gene)|ensembl:ENSMUST00000023762(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|rcsb pdb:2CQX|rcsb pdb:5E8N|rcsb pdb:5E8O|rcsb pdb:5E8P|reactome:R-MMU-1660661|refseq:NP_082291.1|entrezgene/locuslink:71949(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:z4swZkbMyG1m6bkAxAl2SaXnrEA10090 rigid:K9/QLZYFHtAowOTvwenfeOE9lYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61216 uniprotkb:P97875 intact:EBI-309424|uniprotkb:Q3TVE8|ensembl:ENSMUSP00000121346 intact:EBI-11515786|ensembl:ENSMUSP00000059724|ensembl:ENSMUSP00000129985|ensembl:ENSMUSP00000136823 psi-mi:taf13_mouse(display_long)|uniprotkb:Taf13(gene name)|psi-mi:Taf13(display_short)|uniprotkb:Taf2k(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 18 kDa subunit(gene name synonym) psi-mi:jdp2_mouse(display_long)|uniprotkb:Jdp2(gene name)|psi-mi:Jdp2(display_short)|uniprotkb:Jundm2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26686209|imex:IM-28774-3159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079720.1|ensembl:ENSMUSG00000048100(gene)|ensembl:ENSMUST00000143054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|entrezgene/locuslink:99730(identity) refseq:NP_001191981.1|refseq:NP_001191982.1|refseq:NP_112149.2|ensembl:ENSMUSG00000034271(gene)|ensembl:ENSMUST00000050687(transcript)|ensembl:ENSMUST00000177587(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029819|ensembl:ENSMUST00000171754(transcript)|entrezgene/locuslink:81703(identity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho_k1)|taxid:10029(Cricetulus griseus ovary K1) - 2021/02/23 2021/02/23 rogid:7pXO1SLH76kWulpTOtxekJGU8ac10090 rogid:7YlPLGPS9c3SwluhhdJbEc1XD+010090 rigid:dMK/A27TeOd8Q0us1AuNohj9HBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04211 uniprotkb:Q9D8X5 intact:EBI-7847081|ensembl:ENSMUSP00000020692|intact:MINT-1517995 intact:EBI-16204625|ensembl:ENSMUSP00000020822|ensembl:ENSMUSP00000104471|uniprotkb:Q3U532 psi-mi:btg2_mouse(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Tis21(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible protein TIS21(gene name synonym) psi-mi:cnot8_mouse(display_long)|uniprotkb:Cnot8(gene name)|psi-mi:Cnot8(display_short)|uniprotkb:CCR4-associated factor 8(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668004|imex:IM-28774-957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020423(gene)|ensembl:ENSMUST00000020692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|mint:Q04211|rcsb pdb:3DJN|go:"GO:0017148"(negative regulation of translation)|reactome:R-MMU-6804115|refseq:NP_031596.1|dip:DIP-41601N|entrezgene/locuslink:12227(identity) ensembl:ENSMUSG00000020515(gene)|ensembl:ENSMUST00000020822(transcript)|ensembl:ENSMUST00000108843(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|reactome:R-MMU-429947|reactome:R-MMU-6804115|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|refseq:NP_081225.1|refseq:XP_006534165.1|refseq:XP_006534166.1|refseq:XP_006534167.1|refseq:XP_006534168.1|refseq:XP_006534169.1|dip:DIP-61988N|entrezgene/locuslink:69125(identity) - comment:mint|function:Anti-proliferative protein. Modulates transcription regulation mediated by ESR1 - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:7BocM19zCEv3H2oW41XX6DMgaTY10090 rogid:g5iKAkqD6ea+Pn/e/tXlXeIJ97U10090 rigid:AJEC+qFtsKAG989h7nzMPGw7oqg false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q60765 uniprotkb:P05627 intact:EBI-26667953|ensembl:ENSMUSP00000027941|ensembl:ENSMUSP00000141492 intact:EBI-764369|ensembl:ENSMUSP00000102711 psi-mi:atf3_mouse(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:Transcription factor LRG-21(gene name synonym)|uniprotkb:Atf3(gene name)|psi-mi:Atf3(display_short) psi-mi:jun_mouse(display_long)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:AH119(gene name synonym)|uniprotkb:Jun(gene name)|psi-mi:Jun(display_short) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26667995|imex:IM-28774-3155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|ensembl:ENSMUST00000027941(transcript)|ensembl:ENSMUST00000195117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|ensembl:ENSMUSG00000026628(gene)|refseq:NP_031524.2|entrezgene/locuslink:11910(identity) refseq:NP_034721.1|dip:DIP-1068N|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009987"(cellular process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031103"(axon regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0003682"(chromatin binding)|ensembl:ENSMUSG00000052684(gene)|ensembl:ENSMUST00000107094(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05627|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450341|reactome:R-MMU-9018519|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|entrezgene/locuslink:16476(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:XVPcwGRqHiIDNpcxrj7rpMXeNqs10090 rogid:uEOUeeaXEsnmO+XuqF1WfIF96go10090 rigid:FPd1Eb0+2YxNM5lJU3ikcfM0HX8 false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P79621 uniprotkb:Q07279 intact:EBI-26668013|ensembl:ENSMUSP00000155517|uniprotkb:O46787|uniprotkb:O78036|uniprotkb:O78109|uniprotkb:Q31115|uniprotkb:Q9TPP1 intact:EBI-6554737|uniprotkb:Q6P6K5 psi-mi:c2ta_mouse(display_long)|uniprotkb:Ciita(gene name)|psi-mi:Ciita(display_short)|uniprotkb:C2ta(gene name synonym)|uniprotkb:Mhc2ta(gene name synonym) psi-mi:nfe2_mouse(display_long)|uniprotkb:Nfe2(gene name)|psi-mi:Nfe2(display_short)|uniprotkb:Leucine zipper protein NF-E2(gene name synonym)|uniprotkb:Nuclear factor, erythroid-derived 2 45 kDa subunit(gene name synonym)|uniprotkb:p45 NF-E2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26668069|imex:IM-28774-2317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000022504(gene)|ensembl:ENSMUST00000230395(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR027417|interpro:IPR032675|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|refseq:NP_001230690.1|refseq:NP_001289547.1|refseq:NP_001289548.1|refseq:NP_031601.1|refseq:XP_006521788.1|refseq:XP_011244112.1|entrezgene/locuslink:12265(identity) refseq:NP_001289267.1|refseq:NP_001289268.1|refseq:NP_001289269.1|refseq:NP_001289270.1|refseq:NP_001289272.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034242"(negative regulation of syncytium formation by plasma membrane fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050699"(WW domain binding)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029853|refseq:XP_006520636.1|refseq:NP_032711.2|dip:DIP-44849N|reactome:R-MMU-983231|entrezgene/locuslink:18022(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:WJmZ1q1pl0loWdMtkwaWPePErZU10090 rogid:tH9KjHPHKGuyGZE6Klvu6fHqrbY10090 rigid:FWjPJ0e6Y/OCoZeykeQlxwrfWOY false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:O88522 uniprotkb:O88351 intact:EBI-998011|uniprotkb:Q924H4|ensembl:ENSMUSP00000109762|ensembl:ENSMUSP00000109763|ensembl:ENSMUSP00000109768|ensembl:ENSMUSP00000126770 intact:EBI-447960|uniprotkb:Q9R1J6 psi-mi:nemo_mouse(display_long)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:Ikbkg(gene name)|psi-mi:Ikbkg(display_short)|uniprotkb:Nemo(gene name synonym) psi-mi:ikkb_mouse(display_long)|uniprotkb:I-kappa-B kinase 2(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)|uniprotkb:Ikbkb(gene name)|psi-mi:Ikbkb(display_short)|uniprotkb:Ikkb(gene name synonym)|uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26669210|imex:IM-28774-1865 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:O88522|rcsb pdb:2V4H|rcsb pdb:2ZVN|rcsb pdb:2ZVO|rcsb pdb:3F89|rcsb pdb:3JSV|rcsb pdb:4OWF|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-4755510|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-9020702|reactome:R-MMU-933542|reactome:R-MMU-937039|reactome:R-MMU-937041|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-975144|ensembl:ENSMUSG00000004221(gene)|ensembl:ENSMUST00000114127(transcript)|ensembl:ENSMUST00000114128(transcript)|ensembl:ENSMUST00000114133(transcript)|ensembl:ENSMUST00000164101(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|refseq:XP_011245829.1|refseq:NP_001154895.1|refseq:NP_034677.2|refseq:XP_006527913.1|refseq:XP_006527914.1|refseq:XP_006527915.1|dip:DIP-29811N|entrezgene/locuslink:16151(identity) refseq:NP_034676.1|dip:DIP-29813N|mint:O88351|go:"GO:0001782"(B cell homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022007|interpro:IPR041185|reactome:R-MMU-1169091|reactome:R-MMU-168638|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5607764|reactome:R-MMU-5684264|reactome:R-MMU-9020702|reactome:R-MMU-933542|go:"GO:0005829"(cytosol)|reactome:R-MMU-937039|reactome:R-MMU-937041|reactome:R-MMU-975144|entrezgene/locuslink:16150(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:xdq9J5m7CDC1X/4TfHZVGSYKq8U10090 rogid:hpX+Y9AKB4hMKVP4cnfMfvIlPKw10090 rigid:2zyrTVF3L6+LN3C8ep/CHA8OHfg false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:O35317 uniprotkb:P09079 intact:EBI-26671189|ensembl:ENSMUSP00000045281|uniprotkb:Q925W2 intact:EBI-26671239|ensembl:ENSMUSP00000035423|uniprotkb:Q3ZAY8 psi-mi:pbx3_mouse(display_long)|uniprotkb:Homeobox protein PBX3(gene name synonym)|uniprotkb:Pbx3(gene name)|psi-mi:Pbx3(display_short) psi-mi:hxb5_mouse(display_long)|uniprotkb:Homeobox protein H24.1(gene name synonym)|uniprotkb:Homeobox protein Hox-2.1(gene name synonym)|uniprotkb:Homeobox protein Mu-1(gene name synonym)|uniprotkb:Hoxb5(gene name)|psi-mi:Hoxb5(display_short)|uniprotkb:Hox-2.1(gene name synonym)|uniprotkb:Hoxb-5(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26671280|imex:IM-28774-959 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038718(gene)|ensembl:ENSMUST00000040638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021516"(dorsal spinal cord development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048666"(neuron development)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001277505.1|refseq:NP_058048.1|entrezgene/locuslink:18516(identity) ensembl:ENSMUSG00000038700(gene)|ensembl:ENSMUST00000049272(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017995|interpro:IPR020479|interpro:IPR017970|refseq:NP_032294.2|entrezgene/locuslink:15413(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:fi8dSLtqlkzrh42CuyAhsM6EDqY10090 rogid:s8SXxXXrPmirctRlLvsBnwGqa/w10090 rigid:hpK1krsYm3DfnRX8cL6UklJNZe8 false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q8C7B8 uniprotkb:Q61545 intact:EBI-26673088|ensembl:ENSMUSP00000040078|uniprotkb:Q8BPN9 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:zswm4_mouse(display_long)|uniprotkb:Zswim4(gene name)|psi-mi:Zswim4(display_short) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673110|imex:IM-28774-3581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000035671(gene)|ensembl:ENSMUST00000039480(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR007527(Zinc finger, SWIM-type)|refseq:NP_766091.2|entrezgene/locuslink:212168(identity) refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript)|entrezgene/locuslink:14030(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:RkRkScsaRBPtD5FjSOBpBdu2DM010090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 rigid:44ufBWzgXimQLVeBznEQJOqxBow false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q60769 uniprotkb:Q9CYZ8 intact:EBI-646595|uniprotkb:Q3U968|ensembl:ENSMUSP00000019997|ensembl:ENSMUSP00000101167 intact:EBI-309962|uniprotkb:Q99LX9|uniprotkb:B1B188|ensembl:ENSMUSP00000004094 psi-mi:tnap3_mouse(display_long)|uniprotkb:Putative DNA-binding protein A20(gene name synonym)|uniprotkb:Zinc finger protein A20(gene name synonym)|uniprotkb:Tnfaip3(gene name)|psi-mi:Tnfaip3(display_short)|uniprotkb:Tnfip3(gene name synonym) psi-mi:ssbp2_mouse(display_long)|uniprotkb:Ssbp2(gene name)|psi-mi:Ssbp2(display_short)|uniprotkb:Ssdp2(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26673951|imex:IM-28774-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033423.3|dip:DIP-41120N|refseq:XP_006512765.1|ensembl:ENSMUSG00000019850(gene)|ensembl:ENSMUST00000019997(transcript)|ensembl:ENSMUST00000105527(transcript)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002632"(negative regulation of granuloma formation)|go:"GO:0002634"(regulation of germinal center formation)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002677"(negative regulation of chronic inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019900"(kinase binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034148"(negative regulation of toll-like receptor 5 signaling pathway)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070429"(negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0072573"(tolerance induction to lipopolysaccharide)|go:"GO:0072666"(establishment of protein localization to vacuole)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1990168"(protein K33-linked deubiquitination)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000349"(negative regulation of CD40 signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR033478|mint:Q60769|rcsb pdb:5DQ6|reactome:R-MMU-168638|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5689896|reactome:R-MMU-936440|entrezgene/locuslink:21929(identity) refseq:NP_077148.1|refseq:NP_077234.2|ensembl:ENSMUSG00000003992(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSMUST00000004094(transcript)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9CYZ8|entrezgene/locuslink:66970(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:hFNjd3fxx9grjtEq3kAdU0fiFh010090 rogid:YUUExLJthieChUovaHvCaOJJZac10090 rigid:IuQ0YvzWIdmEayRPa98GkOZf/Vc false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q8CFD5 uniprotkb:Q61473 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-9106822|uniprotkb:Q61472|uniprotkb:Q62248|ensembl:ENSMUSP00000027035|ensembl:ENSMUSP00000112351 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:sox17_mouse(display_long)|uniprotkb:Sox17(gene name)|psi-mi:Sox17(display_short)|uniprotkb:Sox-17(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682223|imex:IM-28774-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) refseq:XP_011236666.1|refseq:NP_035571.1|refseq:XP_006495537.1|refseq:XP_006495538.1|refseq:NP_001276393.1|refseq:NP_001276394.1|refseq:NP_001276396.1|ensembl:ENSMUSG00000025902(gene)|ensembl:ENSMUST00000027035(transcript)|ensembl:ENSMUST00000116652(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001656"(metanephros development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001828"(inner cell mass cellular morphogenesis)|go:"GO:0001947"(heart looping)|go:"GO:0003142"(cardiogenic plate morphogenesis)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003308"(negative regulation of Wnt signaling pathway involved in heart development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007369"(gastrulation)|go:"GO:0007492"(endoderm development)|go:"GO:0007493"(endodermal cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031648"(protein destabilization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050821"(protein stabilization)|go:"GO:0060214"(endocardium formation)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061009"(common bile duct development)|go:"GO:0061010"(gall bladder development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000043"(regulation of cardiac cell fate specification)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR021934|interpro:IPR033392|interpro:IPR036910|rcsb pdb:3F27|rcsb pdb:6L6Y|reactome:R-MMU-3769402|entrezgene/locuslink:20671(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:FDK0NpFrGw9qcDFSiFKSvlRxEAI10090 rigid:JqzSgaWc8RPPp2KtUO23XB1+vsA false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q8CFD5 uniprotkb:Q06507 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-77383|uniprotkb:Q5U4B2|uniprotkb:Q61906|ensembl:ENSMUSP00000105234 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:atf4_mouse(display_long)|uniprotkb:Atf4(gene name)|psi-mi:Atf4(display_short)|uniprotkb:C/EBP-related ATF(gene name synonym)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:Creb2(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682174|imex:IM-28774-2701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) refseq:NP_033846.2|refseq:NP_001274109.1|dip:DIP-30969N|ensembl:ENSMUSG00000042406(gene)|ensembl:ENSMUST00000109605(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|interpro:IPR029811|rcsb pdb:6IRR|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|entrezgene/locuslink:11911(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:tNLuKEB2zKt5bpWuvhOVWJkkWNw10090 rigid:iT+mLQNVxCGf4svM66ca577XqFg false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q8CFD5 uniprotkb:Q3U4B1 intact:EBI-26682118|ensembl:ENSMUSP00000059211|uniprotkb:Q3U066|uniprotkb:Q8VDC4|uniprotkb:Q9CWK7 intact:EBI-26666280|ensembl:ENSMUSP00000059039 psi-mi:ercc8_mouse(display_long)|uniprotkb:Cockayne syndrome WD repeat protein CSA homolog(gene name synonym)|uniprotkb:Ercc8(gene name)|psi-mi:Ercc8(display_short)|uniprotkb:Ckn1(gene name synonym)|uniprotkb:Csa(gene name synonym) psi-mi:q3u4b1_mouse(display_long)|uniprotkb:Ssbp4(gene name)|psi-mi:Ssbp4(display_short) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26682240|imex:IM-28774-3583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021694(gene)|ensembl:ENSMUST00000054835(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010165"(response to X-ray)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042238|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-8951664|refseq:NP_082318.2|entrezgene/locuslink:71991(identity) ensembl:ENSMUSG00000070003(gene)|ensembl:ENSMUST00000049908(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|refseq:NP_598533.2|entrezgene/locuslink:76900(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:1OlObmoMEXm31TvVpE231gS8lx410090 rogid:Ch7ZraKBOxvhVXq1mMDdJ/1FLf410090 rigid:q+0Bkfp0w06fskfq7wS3LBWTxWg false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q8VHS6 uniprotkb:Q80W03 intact:EBI-26675998|ensembl:ENSMUSP00000031696|ensembl:ENSMUSP00000112965|uniprotkb:Q8CDP8 intact:EBI-26675915|ensembl:ENSMUSP00000105250|uniprotkb:Q8BIV8 psi-mi:asb15_mouse(display_long)|uniprotkb:Asb15(gene name)|psi-mi:Asb15(display_short) psi-mi:tox3_mouse(display_long)|uniprotkb:Trinucleotide repeat-containing gene 9 protein(gene name synonym)|uniprotkb:Tox3(gene name)|psi-mi:Tox3(display_short)|uniprotkb:Tnrc9(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26683674|imex:IM-28774-2703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029685(gene)|ensembl:ENSMUST00000031696(transcript)|ensembl:ENSMUST00000117688(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|refseq:NP_543123.2|refseq:XP_011239391.1|entrezgene/locuslink:78910(identity) ensembl:ENSMUSG00000043668(gene)|ensembl:ENSMUST00000109621(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_766501.2|entrezgene/locuslink:244579(identity) - - - figure legend:Table S4|caution:Participant experimental roles were not specified in this experiment. The bait is biotinylated and the prey labeled with 35S, but we cannot tell which one is which.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:k90YXTebsFC0kF2V8wAQe54DFVM10090 rogid:jovO+VOsVtKETxrcmpw8SGacl6o10090 rigid:y8X7ZngT0aKyJMglKMqweBVHikw false - - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P04150 uniprotkb:P28702 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854620|imex:IM-28774-3584 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development) - - - figure legend:4Bi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:ShQxqW4BpaAXDi3p5nFD97G6c5w false biotin tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P04150 uniprotkb:P28702 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854649|imex:IM-28774-3586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development) - - - figure legend:4Bii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:ShQxqW4BpaAXDi3p5nFD97G6c5w false 35s radiolabel:?-? biotin tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P37231 uniprotkb:P28702 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854666|imex:IM-28774-3588 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development) - - - figure legend:4Biii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:pZTE4AQtemXgnjnnnnR7+ln1Q9c false biotin tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P37231 uniprotkb:P28702 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 intact:EBI-748576|uniprotkb:P28703|uniprotkb:Q59G65|uniprotkb:Q5JP92|uniprotkb:Q5STQ1|ensembl:ENSP00000363812|ensembl:ENSP00000372704|ensembl:ENSP00000402506|ensembl:ENSP00000410468|ensembl:ENSP00000411238|ensembl:ENSP00000415199 psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:rxrb_human(display_long)|uniprotkb:Retinoid X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 2(gene name synonym)|uniprotkb:RXRB(gene name)|psi-mi:RXRB(display_short)|uniprotkb:NR2B2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854713|imex:IM-28774-3590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 refseq:NP_068811.1|refseq:NP_001257330.1|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1H9U|rcsb pdb:1UHL|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5KYA|rcsb pdb:5KYJ|rcsb pdb:7A78|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-5362517|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974|ensembl:ENSG00000204231(gene)|ensembl:ENSG00000206289(gene)|ensembl:ENSG00000227322(gene)|ensembl:ENSG00000228333(gene)|ensembl:ENSG00000231321(gene)|ensembl:ENSG00000235712(gene)|ensembl:ENST00000374680(transcript)|ensembl:ENST00000383217(transcript)|ensembl:ENST00000415157(transcript)|ensembl:ENST00000415909(transcript)|ensembl:ENST00000431820(transcript)|ensembl:ENST00000436753(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development) - - - figure legend:4Biv|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rogid:i5hD8MMgynw4AEw2nJBHjevjDQ89606 rigid:pZTE4AQtemXgnjnnnnR7+ln1Q9c false 35s radiolabel:?-? biotin tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q13485 uniprotkb:P23769 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854726|imex:IM-28774-3592 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) - - - figure legend:4Bv|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:mPu190hmySGV54KAtldys/IHuo89606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 rigid:3pHAGk6pMHVRa25Httc5nyegQ6g false 35s radiolabel:?-? biotin tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q13485 uniprotkb:P23769 intact:EBI-347263|uniprotkb:A8K405|ensembl:ENSP00000341551|ensembl:ENSP00000381452 intact:EBI-2806671|uniprotkb:Q96BH0|uniprotkb:Q9BUJ6|uniprotkb:Q53YE0|uniprotkb:D3DNB3|uniprotkb:Q96BH8|ensembl:ENSP00000345681|ensembl:ENSP00000417074 psi-mi:smad4_human(display_long)|uniprotkb:SMAD4(gene name)|psi-mi:SMAD4(display_short)|uniprotkb:DPC4(gene name synonym)|uniprotkb:MADH4(gene name synonym)|uniprotkb:SMAD family member 4(gene name synonym)|uniprotkb:Deletion target in pancreatic carcinoma 4(gene name synonym) psi-mi:gata2_human(display_long)|uniprotkb:GATA-binding protein 2(gene name synonym)|uniprotkb:GATA2(gene name)|psi-mi:GATA2(display_short) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854743|imex:IM-28774-3594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141646(gene)|refseq:NP_005350.1|ensembl:ENST00000398417(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003148"(outflow tract septum morphogenesis)|ensembl:ENST00000342988(transcript)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003251"(positive regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003360"(brainstem development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0033686"(positive regulation of luteinizing hormone secretion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046881"(positive regulation of follicle-stimulating hormone secretion)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048589"(developmental growth)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048859"(formation of anatomical boundary)|go:"GO:0051098"(regulation of binding)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051797"(regulation of hair follicle development)|go:"GO:0060065"(uterus development)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0061040"(female gonad morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062009"(secondary palate development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0072133"(metanephric mesenchyme morphogenesis)|go:"GO:0072134"(nephrogenic mesenchyme morphogenesis)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1905305"(negative regulation of cardiac myofibril assembly)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|mint:Q13485|rcsb pdb:1DD1|rcsb pdb:1G88|rcsb pdb:1MR1|rcsb pdb:1U7F|rcsb pdb:1U7V|rcsb pdb:1YGS|rcsb pdb:5C4V|rcsb pdb:5MEY|rcsb pdb:5MEZ|rcsb pdb:5MF0|rcsb pdb:5UWU|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-201451|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-8941326|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9615017|reactome:R-HSA-9617828|dip:DIP-31512N refseq:NP_001139133.1|refseq:NP_001139134.1|refseq:NP_116027.2|dip:DIP-29711N|go:"GO:0001764"(neuron migration)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006909"(phagocytosis)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001709"(cell fate determination)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0033993"(response to lipid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060872"(semicircular canal development)|go:"GO:0061042"(vascular wound healing)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097154"(GABAergic neuron differentiation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000977"(regulation of forebrain neuron differentiation)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016374(Transcription factor, GATA-1/2/3)|interpro:IPR029522|interpro:IPR039355|rcsb pdb:5O9B|rcsb pdb:6ZFV|reactome:R-HSA-8939236|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000179348(gene)|ensembl:ENST00000341105(transcript)|ensembl:ENST00000487848(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development) - - - figure legend:4Bvi|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:mPu190hmySGV54KAtldys/IHuo89606 rogid:tQNHxMqtJhW3+fsILE9055QZoWc9606 rigid:3pHAGk6pMHVRa25Httc5nyegQ6g false biotin tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q01543 uniprotkb:P84022 intact:EBI-2271018|uniprotkb:B4DFV4|uniprotkb:Q14319|uniprotkb:Q92480|uniprotkb:Q9UE07|uniprotkb:B2R8H2|uniprotkb:B4DTC6|uniprotkb:G3V183|ensembl:ENSP00000433488 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:fli1_human(display_long)|uniprotkb:FLI1(gene name)|psi-mi:FLI1(display_short)|uniprotkb:Proto-oncogene Fli-1(gene name synonym)|uniprotkb:Transcription factor ERGB(gene name synonym) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854758|imex:IM-28774-3596 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002008.2|refseq:NP_001161153.1|refseq:NP_001257939.1|refseq:NP_001257941.1|go:"GO:0030154"(cell differentiation)|go:"GO:0035855"(megakaryocyte development)|ensembl:ENSG00000151702(gene)|ensembl:ENST00000527786(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007599"(hemostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016604"(nuclear body)|refseq:XP_011541003.1|refseq:XP_016872894.1|refseq:XP_016872895.1|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035573|interpro:IPR035575|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1FLI|rcsb pdb:1X66|rcsb pdb:2YTU|rcsb pdb:5E8G|rcsb pdb:5E8I|rcsb pdb:5JVT|rcsb pdb:6VG2|rcsb pdb:6VG8|rcsb pdb:6VGD|reactome:R-HSA-9616222 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - - - figure legend:4Bvii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:WCQw202NBbJxHliWsFCoYNv45WM9606 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:RfCYWlWP9Df3mX3Hn981T8fTNf8 false biotin tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q01543 uniprotkb:P84022 intact:EBI-2271018|uniprotkb:B4DFV4|uniprotkb:Q14319|uniprotkb:Q92480|uniprotkb:Q9UE07|uniprotkb:B2R8H2|uniprotkb:B4DTC6|uniprotkb:G3V183|ensembl:ENSP00000433488 intact:EBI-347161|intact:EBI-1760241|uniprotkb:O09064|uniprotkb:O09144|uniprotkb:O14510|uniprotkb:O35273|uniprotkb:Q92940|uniprotkb:Q93002|uniprotkb:Q9GKR4|intact:EBI-1965323|uniprotkb:A8K4B6|uniprotkb:B7Z9Q2|uniprotkb:B7Z4Z5|uniprotkb:B7Z6M9|uniprotkb:F5H383|ensembl:ENSP00000332973 psi-mi:fli1_human(display_long)|uniprotkb:FLI1(gene name)|psi-mi:FLI1(display_short)|uniprotkb:Proto-oncogene Fli-1(gene name synonym)|uniprotkb:Transcription factor ERGB(gene name synonym) psi-mi:smad3_human(display_long)|uniprotkb:SMAD3(gene name)|psi-mi:SMAD3(display_short)|uniprotkb:MADH3(gene name synonym)|uniprotkb:SMAD family member 3(gene name synonym)|uniprotkb:JV15-2(gene name synonym) psi-mi:"MI:0096"(pull down) Ravasi et al. (2010) pubmed:20211142|doi:10.1016/j.cell.2010.01.044|imex:IM-28774 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26854779|imex:IM-28774-3598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002008.2|refseq:NP_001161153.1|refseq:NP_001257939.1|refseq:NP_001257941.1|go:"GO:0030154"(cell differentiation)|go:"GO:0035855"(megakaryocyte development)|ensembl:ENSG00000151702(gene)|ensembl:ENST00000527786(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007599"(hemostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016604"(nuclear body)|refseq:XP_011541003.1|refseq:XP_016872894.1|refseq:XP_016872895.1|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035573|interpro:IPR035575|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1FLI|rcsb pdb:1X66|rcsb pdb:2YTU|rcsb pdb:5E8G|rcsb pdb:5E8I|rcsb pdb:5JVT|rcsb pdb:6VG2|rcsb pdb:6VG8|rcsb pdb:6VGD|reactome:R-HSA-9616222 refseq:NP_001138574.1|refseq:NP_001138575.1|refseq:NP_005893.1|refseq:NP_001138576.1|dip:DIP-29720N|ensembl:ENSG00000166949(gene)|ensembl:ENST00000327367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002076"(osteoblast development)|go:"GO:0002520"(immune system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031962"(mineralocorticoid receptor binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042110"(T cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051098"(regulation of binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060039"(pericardium development)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061767"(negative regulation of lung blood pressure)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:1901203"(positive regulation of extracellular matrix assembly)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:P84022|rcsb pdb:1MHD|rcsb pdb:1MJS|rcsb pdb:1MK2|rcsb pdb:1OZJ|rcsb pdb:1U7F|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:5OD6|rcsb pdb:5ODG|rcsb pdb:5XOC|rcsb pdb:6ZMN|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-5689880|reactome:R-HSA-8941855|reactome:R-HSA-8952158|reactome:R-HSA-9008059|reactome:R-HSA-9013695|reactome:R-HSA-9615017|reactome:R-HSA-9617828 - - - figure legend:4Bviii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/23 2021/03/01 rogid:WCQw202NBbJxHliWsFCoYNv45WM9606 rogid:47/62Iz3MOJAyDNCYtisL+unRDg9606 rigid:RfCYWlWP9Df3mX3Hn981T8fTNf8 false 35s radiolabel:?-? biotin tag:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)