#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UMF0	uniprotkb:P20701	intact:EBI-6398041|ensembl:ENSP00000221980|uniprotkb:Q9Y6F3	intact:EBI-961214|ensembl:ENSP00000349252|uniprotkb:O43746|uniprotkb:Q45H73|uniprotkb:Q9UBC8|intact:EBI-3962403|uniprotkb:Q96HB1	psi-mi:icam5_human(display_long)|uniprotkb:ICAM5(gene name)|psi-mi:ICAM5(display_short)|uniprotkb:TLCN(gene name synonym)|uniprotkb:TLN(gene name synonym)|uniprotkb:Telencephalin(gene name synonym)	psi-mi:ital_human(display_long)|uniprotkb:ITGAL(gene name)|psi-mi:ITGAL(display_short)|uniprotkb:CD11A(gene name synonym)|uniprotkb:Leukocyte adhesion glycoprotein LFA-1 alpha chain(gene name synonym)|uniprotkb:Leukocyte function-associated molecule 1 alpha chain(gene name synonym)|uniprotkb:CD11 antigen-like family member A(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Zhang et al. (2008)	imex:IM-28963|pubmed:18691975	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26959603|imex:IM-28963-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011526531.1|ensembl:ENSG00000105376(gene)|ensembl:ENST00000221980(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:3BN3|rcsb pdb:4OI9|rcsb pdb:4OIA|rcsb pdb:4OIB|reactome:R-HSA-198933|reactome:R-HSA-216083|interpro:IPR036179|refseq:NP_003250.3	refseq:NP_002200.2|ensembl:ENSG00000005844(gene)|ensembl:ENST00000356798(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035683"(memory T cell extravasation)|go:"GO:0043113"(receptor clustering)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|rcsb pdb:1CQP|rcsb pdb:1DGQ|rcsb pdb:1IJ4|rcsb pdb:1LFA|rcsb pdb:1MJN|rcsb pdb:1MQ8|rcsb pdb:1MQ9|rcsb pdb:1MQA|rcsb pdb:1RD4|rcsb pdb:1T0P|rcsb pdb:1XDD|rcsb pdb:1XDG|rcsb pdb:1XUO|rcsb pdb:1ZON|rcsb pdb:1ZOO|rcsb pdb:1ZOP|rcsb pdb:2ICA|rcsb pdb:2K8O|rcsb pdb:2M3E|rcsb pdb:2O7N|rcsb pdb:3BN3|rcsb pdb:3BQM|rcsb pdb:3BQN|rcsb pdb:3E2M|rcsb pdb:3EOA|rcsb pdb:3EOB|rcsb pdb:3F74|rcsb pdb:3HI6|rcsb pdb:3F78|rcsb pdb:3M6F|rcsb pdb:3TCX|rcsb pdb:4IXD|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:6BXB|rcsb pdb:6BXF|rcsb pdb:6BXJ|rcsb pdb:6CKB|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6798695|reactome:R-HSA-8949275|refseq:NP_001107852.1|dip:DIP-623N	pdbe:3bn3	-	-	figure legend:Fig.1, Table 1|3d-resolution:Resolution=2.1A|3d-r-factors:Rwork=1.91  Rfree=2.35|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/04/21	2021/05/10	rogid:rL67QmGOsnIz99HXTOYoxzE1bWU9606	rogid:JeiBJZbkw8mtrE7WrFlkepPiAOY9606	-	false	sufficient binding region:32-227|mono-N-acetylaminoglucosylated residue:74-74	variant:214-214(rs1064524)|mutation:290-290|mutation:317-317|sufficient binding region:154-332	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:18420"	uniprotkb:Q9UMF0	intact:EBI-967760	intact:EBI-6398041|ensembl:ENSP00000221980|uniprotkb:Q9Y6F3	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:icam5_human(display_long)|uniprotkb:ICAM5(gene name)|psi-mi:ICAM5(display_short)|uniprotkb:TLCN(gene name synonym)|uniprotkb:TLN(gene name synonym)|uniprotkb:Telencephalin(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Zhang et al. (2008)	imex:IM-28963|pubmed:18691975	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26959603|imex:IM-28963-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011526531.1|ensembl:ENSG00000105376(gene)|ensembl:ENST00000221980(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003988(Intercellular adhesion molecule)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:3BN3|rcsb pdb:4OI9|rcsb pdb:4OIA|rcsb pdb:4OIB|reactome:R-HSA-198933|reactome:R-HSA-216083|interpro:IPR036179|refseq:NP_003250.3	pdbe:3bn3	-	-	figure legend:Fig.1, Table 1|3d-resolution:Resolution=2.1A|3d-r-factors:Rwork=1.91  Rfree=2.35|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/04/21	2021/05/10	-	rogid:rL67QmGOsnIz99HXTOYoxzE1bWU9606	-	false	-	sufficient binding region:32-227|mono-N-acetylaminoglucosylated residue:74-74	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)