#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92643	uniprotkb:O43292	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873359|imex:IM-28798-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	glutathione s tranferase tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:Q92643	uniprotkb:Q9H490	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-11290294|uniprotkb:Q7Z489|uniprotkb:Q8N2F2|ensembl:ENSP00000217446	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigu_human(display_long)|uniprotkb:PIGU(gene name)|psi-mi:PIGU(display_short)|uniprotkb:CDC91L1(gene name synonym)|uniprotkb:Cell division cycle protein 91-like 1(gene name synonym)|uniprotkb:GPI transamidase component PIG-U(gene name synonym)|uniprotkb:PSEC0205(orf name)|uniprotkb:UNQ3055/PRO9875(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873359|imex:IM-28798-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_536724.1|ensembl:ENSG00000101464(gene)|ensembl:ENST00000217446(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|interpro:IPR009600(GPI transamidase subunit PIG-U)|reactome:R-HSA-162791	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:mIQ3RyNGs+D8Tov04aSq1zWT5Uk9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	glutathione s tranferase tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:Q92643	uniprotkb:Q96S52	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873359|imex:IM-28798-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	glutathione s tranferase tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:Q92643	uniprotkb:Q969N2	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873359|imex:IM-28798-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	glutathione s tranferase tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:Q96S52	uniprotkb:Q92643	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873405|imex:IM-28798-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	ha tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:O43292	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873405|imex:IM-28798-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	ha tag:?-?	tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q9H490	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-11290294|uniprotkb:Q7Z489|uniprotkb:Q8N2F2|ensembl:ENSP00000217446	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:pigu_human(display_long)|uniprotkb:PIGU(gene name)|psi-mi:PIGU(display_short)|uniprotkb:CDC91L1(gene name synonym)|uniprotkb:Cell division cycle protein 91-like 1(gene name synonym)|uniprotkb:GPI transamidase component PIG-U(gene name synonym)|uniprotkb:PSEC0205(orf name)|uniprotkb:UNQ3055/PRO9875(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873405|imex:IM-28798-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_536724.1|ensembl:ENSG00000101464(gene)|ensembl:ENST00000217446(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|interpro:IPR009600(GPI transamidase subunit PIG-U)|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:mIQ3RyNGs+D8Tov04aSq1zWT5Uk9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	ha tag:?-?	flag tag:?-?|mutation with no effect:274-275	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q969N2	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873405|imex:IM-28798-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:K3DnBd8kItPBWOLJ8yAasMXb0n4	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q92643	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873548|imex:IM-28798-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	ha tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:O43292	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873548|imex:IM-28798-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	ha tag:?-?	tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q969N2	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hong et al. (2003)	imex:IM-28798|pubmed:12802054	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873548|imex:IM-28798-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7B, 9D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)