#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43292	uniprotkb:Q92643	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873010|imex:IM-28800-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	-	flag tag:c-c|glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:O43292	uniprotkb:Q96S52	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873010|imex:IM-28800-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	-	-	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:O43292	uniprotkb:Q969N2	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873010|imex:IM-28800-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	-	-	-	-	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0039"(edman degradation)
uniprotkb:Q92643	uniprotkb:Q969N2	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873028|imex:IM-28800-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	glutathione s tranferase tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q96S52	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873028|imex:IM-28800-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	glutathione s tranferase tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:O43292	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873028|imex:IM-28800-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	glutathione s tranferase tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q92643	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873046|imex:IM-28800-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	flag tag:n-n	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q969N2	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873046|imex:IM-28800-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	flag tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q96S52	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873046|imex:IM-28800-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	flag tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q92643	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873060|imex:IM-28800-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	ha tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q969N2	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873060|imex:IM-28800-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:O43292	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873060|imex:IM-28800-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	ha tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q92643	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873074|imex:IM-28800-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	myc tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q96S52	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873074|imex:IM-28800-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:O43292	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873074|imex:IM-28800-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:qHg8g9tylu6nH+YKkBjTp+0x/jU	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q969N2	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873088|imex:IM-28800-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|comment:Interaction observed in GPAA1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:8I+Z9cKWKBjYPbMeZUsCPLj8OSQ	false	glutathione s tranferase tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q96S52	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873088|imex:IM-28800-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|comment:Interaction observed in GPAA1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:8I+Z9cKWKBjYPbMeZUsCPLj8OSQ	false	glutathione s tranferase tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q92643	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873100|imex:IM-28800-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|comment:Interaction observed in GPAA1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:8I+Z9cKWKBjYPbMeZUsCPLj8OSQ	false	ha tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q969N2	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873100|imex:IM-28800-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in GPAA1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:8I+Z9cKWKBjYPbMeZUsCPLj8OSQ	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q92643	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873112|imex:IM-28800-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|comment:Interaction observed in GPAA1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:8I+Z9cKWKBjYPbMeZUsCPLj8OSQ	false	myc tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q96S52	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873112|imex:IM-28800-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in GPAA1 -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:8I+Z9cKWKBjYPbMeZUsCPLj8OSQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q92643	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873124|imex:IM-28800-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|comment:Interaction observed in PIGS -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:veX3xEd7dAhhzR5RRX0HI1oXkMQ	false	flag tag:n-n	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q969N2	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873124|imex:IM-28800-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGS -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:veX3xEd7dAhhzR5RRX0HI1oXkMQ	false	flag tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q969N2	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873136|imex:IM-28800-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|comment:Interaction observed in PIGS -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:veX3xEd7dAhhzR5RRX0HI1oXkMQ	false	glutathione s tranferase tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:O43292	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873136|imex:IM-28800-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|comment:Interaction observed in PIGS -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:veX3xEd7dAhhzR5RRX0HI1oXkMQ	false	glutathione s tranferase tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q92643	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873148|imex:IM-28800-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|comment:Interaction observed in PIGS -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:veX3xEd7dAhhzR5RRX0HI1oXkMQ	false	myc tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:O43292	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873148|imex:IM-28800-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGS -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:veX3xEd7dAhhzR5RRX0HI1oXkMQ	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q969N2	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873160|imex:IM-28800-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGK -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	flag tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q96S52	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873160|imex:IM-28800-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGK -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	flag tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q969N2	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873172|imex:IM-28800-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGK -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:O43292	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873172|imex:IM-28800-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGK -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	ha tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q96S52	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873184|imex:IM-28800-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:O43292	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873184|imex:IM-28800-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q92643	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873203|imex:IM-28800-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|comment:Interaction observed in PIGT-/- cells, expression of FLAG- GAA1 and GST–GPI8 was markedly decreased|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:Tjtl1vEsBTFqCO56cG3pEUQp5+4	false	flag tag:n-n	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O43292	uniprotkb:Q96S52	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873203|imex:IM-28800-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGT-/- cells, expression of FLAG- GAA1 and GST–GPI8 was markedly decreased|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:Tjtl1vEsBTFqCO56cG3pEUQp5+4	false	flag tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q96S52	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873214|imex:IM-28800-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|comment:Interaction observed in PIGT-/- cells, expression of FLAG- GAA1 and GST–GPI8 was markedly decreased|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:Tjtl1vEsBTFqCO56cG3pEUQp5+4	false	glutathione s tranferase tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:O43292	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873214|imex:IM-28800-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7A|comment:Interaction observed in PIGT-/- cells, expression of FLAG- GAA1 and GST–GPI8 was markedly decreased|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:Tjtl1vEsBTFqCO56cG3pEUQp5+4	false	glutathione s tranferase tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:Q92643	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873228|imex:IM-28800-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	-	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	figure legend:Fig. 7A|comment:Interaction observed in PIGT-/- cells, expression of FLAG- GAA1 and GST–GPI8 was markedly decreased|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rigid:Tjtl1vEsBTFqCO56cG3pEUQp5+4	false	ha tag:?-?	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96S52	uniprotkb:O43292	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873228|imex:IM-28800-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGT-/- cells, expression of FLAG- GAA1 and GST–GPI8 was markedly decreased|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:Tjtl1vEsBTFqCO56cG3pEUQp5+4	false	ha tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:O43292	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873262|imex:IM-28800-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:EZ+U4QZXV7e0Mx8Jd+TboXgVfGQ	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q969N2	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873271|imex:IM-28800-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:Gl9UVK/5htXGgtdG/W2gOLLfgrA	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q96S52	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873280|imex:IM-28800-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:qr4r2Xp/5cX974OpaYHFY4X8Wlw	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q96S52	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26873289|imex:IM-28800-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/09	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:qr4r2Xp/5cX974OpaYHFY4X8Wlw	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:Q96S52	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26874258|imex:IM-28800-42	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGK -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/11	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:O43292	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26874258|imex:IM-28800-42	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7A|comment:Interaction observed in PIGK -/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/11	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:3eECiERCil6Gs7l+UUw0DamgGEs	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q969N2	uniprotkb:O43292	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26874270|imex:IM-28800-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791	-	-	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/11	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606	rigid:EZ+U4QZXV7e0Mx8Jd+TboXgVfGQ	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92643	uniprotkb:Q969N2	intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ohishi et al. (2001)	pubmed:11483512|imex:IM-28800	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26874278|imex:IM-28800-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	-	function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2021/03/09	2021/03/11	rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:Gl9UVK/5htXGgtdG/W2gOLLfgrA	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)